LOCUS       CP063564               17093 bp    DNA     circular BCT 04-APR-2022
DEFINITION  Enterococcus faecium strain ICU-3-1 plasmid pZA3-1_02, complete
            sequence.
ACCESSION   CP063564
VERSION     CP063564.1
DBLINK      BioProject: PRJNA669626
            BioSample: SAMN16483163
KEYWORDS    .
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17093)
  AUTHORS   Both,A., Kruse,F., Mirwald,N., Franke,G., Christner,M., Huang,J.,
            Hansen,J.L., Kroger,N., Berneking,L., Lellek,H., Aepfelbacher,M. and
            Rohde,H.
  TITLE     Population dynamics in colonizing vancomycin-resistant Enterococcus
            faecium isolated from immunosuppressed patients
  JOURNAL   J Glob Antimicrob Resist 28, 267-273 (2022)
   PUBMED   35134550
REFERENCE   2  (bases 1 to 17093)
  AUTHORS   Both,A., Kruse,F., Christner,M., Huang,J., Mirwald,N., Franke,G. and
            Rohde,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-OCT-2020) Institute of Medical Microbiology, Virology
            and Hygiene, University Medical Center Hamburg-Eppendorf,
            Martinistr. 52, Hamburg, Hamburg 20246, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Trycycler v. v0.3.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 648.2x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 10/27/2020 16:23:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 4.13
            Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region
            Genes (total)                     :: 3,201
            CDSs (total)                      :: 3,108
            Genes (coding)                    :: 2,984
            CDSs (with protein)               :: 2,984
            Genes (RNA)                       :: 93
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 124
            CDSs (without protein)            :: 124
            Pseudo Genes (ambiguous residues) :: 0 of 124
            Pseudo Genes (frameshifted)       :: 49 of 124
            Pseudo Genes (incomplete)         :: 64 of 124
            Pseudo Genes (internal stop)      :: 20 of 124
            Pseudo Genes (multiple problems)  :: 8 of 124
            ##Genome-Annotation-Data-END##
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..17093
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /strain="ICU-3-1"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /plasmid="pZA3-1_02"
                     /geo_loc_name="Germany: Hamburg"
                     /lat_lon="53.33 N 10.1 E"
                     /collection_date="2019-03-01"
                     /collected_by="Institute of Medical Microbiology, Virology
                     and Hygiene, University Medical Center Hamburg-Eppendorf"
     gene            complement(join(15998..17093,1..398))
                     /locus_tag="IQN15_15715"
     CDS             complement(join(15998..17093,1..398))
                     /locus_tag="IQN15_15715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="UOE03103.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSKQ
                     LMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINTFV
                     VDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVIDVA
                     KKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSMKLES
                     DQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTLSLAYY
                     SSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELCQQWVSP
                     TLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLNLSKKELA
                     SQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLSKEKRLDYS
                     TRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
                     /name="primase C-terminal domain-containing protein"
     gene            1010..1963
                     /locus_tag="IQN15_15720"
     CDS             1010..1963
                     /locus_tag="IQN15_15720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="UOE03104.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLFE
                     KDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGSPG
                     SEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAADYII
                     AMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQKTID
                     KYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYYEQHGD
                     IEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
                     /name="ParA family protein"
     gene            1935..2210
                     /locus_tag="IQN15_15725"
     CDS             1935..2210
                     /locus_tag="IQN15_15725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgO"
                     /protein_id="UOE03105.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVDP
                     PVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
                     /name="type III secretion system protein PrgO"
     gene            complement(3114..3284)
                     /locus_tag="IQN15_15730"
     CDS             complement(3114..3284)
                     /locus_tag="IQN15_15730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UOE03106.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAAA
                     GYHKYEYYIGY"
                     /name="hypothetical protein"
     gene            complement(3281..3631)
                     /locus_tag="IQN15_15735"
     CDS             complement(3281..3631)
                     /locus_tag="IQN15_15735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UOE03107.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEKIDADNEQRANQNLAKEQMTTEE
                     VAEVLNAAVIKNRSVCIQKEERNAEGYYPEDIVSKILGSDELGIYVGKNKVHYDEIRHI
                     EFYQDNKWGRLE"
                     /name="hypothetical protein"
     gene            complement(3624..4949)
                     /locus_tag="IQN15_15740"
     CDS             complement(3624..4949)
                     /locus_tag="IQN15_15740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="UOE03108.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRAD
                     NTGSGLILASSPAAKKKYGISNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNIFR
                     RYVADEDLLIYSIDESILKVTRSMNLFTTEGTRSQRRKKLAQMIQENIKEELGLLATVG
                     VGDNPLLAKLALDNEAKHNDGFLAEWTYQNVPDKVWNIPEMTDLWGIGSRMKKRLNQIG
                     IMSIKDLANWNPYTIKSHLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQVLPRD
                     YTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLYIGTSILETRPGFSHQMKIPITDNT
                     KELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEENLDKIIDK
                     IRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGAGGLKND"
                     /name="Y-family DNA polymerase"
     gene            5466..6281
                     /locus_tag="IQN15_15745"
     CDS             5466..6281
                     /locus_tag="IQN15_15745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UOE03109.1"
                     /translation="MVKIAGLSKGGKTVSQLYKQNYRDWRQFRKNIKDSYFILPTELEK
                     YLPNNKAINLYLYYCFKAKNEGGDSWHSVNTIAESLGVTTKTINTWNKTLVDLGMIARI
                     DDNHLSKSTILLPLSSYYKLALDSSLKDVTESTVHEIDGNLVAVYHLFEWRKNEADENY
                     NVPYNTLCCVFKRKTQKDTIYKFILVQDEKISNFELSTPSSKIYDDAYRFECQDLEALL
                     SANNLNNIEHENFVVNTRFNLVSEKDSDLLDLLIELTKNLDKKENITVL"
                     /name="hypothetical protein"
     gene            6407..6664
                     /locus_tag="IQN15_15750"
     CDS             6407..6664
                     /locus_tag="IQN15_15750"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UOE03113.1"
                     /translation="MANLYIENKGDLNAIITLIVVMVKSIGNITIGMLFIILAAVLIFM
                     IVIWFLNERSKDNQHRRDMEIKSIESIDYLSIITLKKPRS"
                     /name="hypothetical protein"
     gene            complement(6916..7488)
                     /locus_tag="IQN15_15755"
     CDS             complement(6916..7488)
                     /locus_tag="IQN15_15755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="UOE03110.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRDR
                     PKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTSMG
                     RMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELLTSG
                     KSYKEVEAITGFSRSTLFRIKKKIEES"
                     /name="recombinase family protein"
     gene            complement(7504..8109)
                     /locus_tag="IQN15_15760"
     CDS             complement(7504..8109)
                     /locus_tag="IQN15_15760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell filamentation protein"
                     /protein_id="UOE03111.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTFK
                     GLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEIIKK
                     YVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDLEIR
                     YLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
                     /name="cell filamentation protein"
     gene            complement(8510..8686)
                     /locus_tag="IQN15_15765"
                     /pseudo=""
     CDS             complement(8510..8686)
                     /locus_tag="IQN15_15765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016181348.1"
                     /note="incomplete; partial on complete genome; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /name="ABC transporter permease"
     gene            complement(8742..9422)
                     /locus_tag="IQN15_15770"
     CDS             complement(8742..9422)
                     /locus_tag="IQN15_15770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="UOE03094.1"
                     /translation="MNPFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            9569..9652
                     /locus_tag="IQN15_15775"
     CDS             9569..9652
                     /locus_tag="IQN15_15775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="UOE03112.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
                     /name="23S rRNA methyltransferase attenuation leader
                     peptide"
     gene            9777..10514
                     /gene="erm(B)"
                     /locus_tag="IQN15_15780"
     ARG             9778..10511
                     /name="erm(B)"
                     /gene="erm(B)"
                     /gene_name="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /tool="amrfinderplus"
                     /drug_class="LINCOSAMIDE/MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(10776..11639)
                     /locus_tag="IQN15_15785"
     CDS             complement(10776..11639)
                     /locus_tag="IQN15_15785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="UOE03096.1"
                     /translation="MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGSG
                     KTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEALIS
                     RLSDQGYNLVIEGTGRTTDVPIQTATMLQSKGYETKIYVMAVPKIESYLGTIERYETMY
                     ADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETPSISP
                     KETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKMESLQLPTPPIPKT
                     PKLPGI"
                     /name="zeta toxin family protein"
     gene            complement(11641..11913)
                     /locus_tag="IQN15_15790"
     CDS             complement(11641..11913)
                     /locus_tag="IQN15_15790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="UOE03097.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEVN
                     LLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYSKQILNKEKVA"
                     /name="antitoxin"
     gene            complement(11930..12139)
                     /locus_tag="IQN15_15795"
     CDS             complement(11930..12139)
                     /locus_tag="IQN15_15795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="UOE03098.1"
                     /translation="MGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAKN
                     GGNVKEVMDQALEEYIRKYLPDKL"
                     /name="peptide-binding protein"
     gene            complement(12217..13113)
                     /locus_tag="IQN15_15800"
     CDS             complement(12217..13113)
                     /locus_tag="IQN15_15800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="UOE03099.1"
                     /translation="MIQYYYTKKEWGVVMEKEKLKILEELRRILNNKNEAIIILNNYFK
                     GGVGKSKLSTMFAYLTDKLNLKVLMIDKDLQATLTKDLAKTFEVELPRVNFYEGLKNGN
                     LASSIIHLTDNLDLIPGTFDLMLLPKLTRSWTFENESRLLATLLAPLKSDYDLIIIDTV
                     PTPSVYTNNAIVASDYVMIPLQAEEESTNNIQNYISYLIDLQEQFNPGLDMIGFVPYLV
                     DTDSATIKSNLEELYKEHKEDNLVFRNIIKRSNKVSTWSKNGITEHKGYDKKVLSMYEN
                     VFFEMIERIIQLENEKE"
                     /name="ParA family protein"
     gene            complement(13269..13949)
                     /locus_tag="IQN15_15805"
     CDS             complement(13269..13949)
                     /locus_tag="IQN15_15805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="UOE03100.1"
                     /translation="MNPFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
                     /name="IS6-like element IS1216 family transposase"
     gene            complement(14311..14594)
                     /locus_tag="IQN15_15810"
                     /pseudo=""
     CDS             complement(14311..14594)
                     /locus_tag="IQN15_15810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345737.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            complement(14615..15466)
                     /locus_tag="IQN15_15815"
     CDS             complement(14615..15466)
                     /locus_tag="IQN15_15815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UOE03101.1"
                     /translation="MKSDDWIEHTWLPLKRNSKRKKFWVLQLWPLGKLCSYGARLILDL
                     TVYSIGVFGTAYYLINDPNRIAASDIFTVLMTLIFVMLLSIFTQLVMQFTRQKLTAGKL
                     FKSLFDLIVVNAILATLIKQIEQSGRTTKGVKDFLLTFIHFVNGHMYLFEVGIILFFVG
                     YVSTKLIKRSIEKEIEIDLIPTLLGYEYNVDFGRYDELINTDIVHTSIHESTVKGIRSI
                     LKNGQEMKAIDRRKEIYNFYEVEASLRYGIGKLWLDGSNIRQNKPYIFWNSSDLELPMK
                     DK"
                     /name="hypothetical protein"
     gene            complement(15567..15863)
                     /locus_tag="IQN15_15820"
     CDS             complement(15567..15863)
                     /locus_tag="IQN15_15820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="UOE03102.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTRE
                     KTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
                     /name="type III secretion system protein PrgN"
     ARG             9778..10514
                     /name="ErmB"
                     /gene="ErmB"
                     /gene_name="Erm 23S ribosomal RNA methyltransferase"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; lincosamide antibiotic;
                     streptogramin antibiotic; streptogramin A antibiotic;
                     streptogramin B antibiotic"
                     /identity="98.37"
                     /coverage="98.79"
     Typing          complement(15999..17093)
                     /name="rep_cluster_185"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.909"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 aaaattagcg ttggcatgta gcccacttga tctaaacagg ctaaaataat ttcgccttga
       61 tggttctctt ttgaatcgat atcaactaca aatgtgttga tttgacttaa gtttttctca
      121 gaatgacctt taaccactgt tcgataatca tccgcataag taccaaagcg ataggtatta
      181 ggtgtccaat gcgttagttt cttttcgttc tctaaaatag cttcttccga agtaatgacc
      241 ataccacgcc caacattcat taattgcttg ctacggtacg caaagatagc accactccta
      301 ctggaatcaa tatgacctgc aggtttcatg gtgctgtttc gatatttgta tgtacgtaag
      361 ccgtttttaa gaatagctga ataaatttcg ctcaacatcg attgtaacgt cctttctcaa
      421 acaaaaagag aacacagttt agctttaatc tcagccatag tatgtgttct ctcttcagtg
      481 tttaagaata tttaatttaa gtacactaaa taaacgttct tctgttgagt tgctcgcctt
      541 tttttggtag aataaaggca atcggaaaag gtatccgatc aacttttaat ataagtagtt
      601 ggtagctact tacatattct tgagacgagc gtgaacacat gtcctaacca tgtgattcag
      661 aaataattga ttctgctaaa atcaattatt tccgtctctt ttttttatgt aatttttctg
      721 tttaaagagt accactgctt ttgctacttt gtaaatagtg aattatctgt ggtttctata
      781 gaattaagtt tacctctttt cactctaaat tgtcaacgca aaacgcacaa atatattttg
      841 acattttgaa tatatctgat atactgaata tagcaaatat atttagtata tccactatat
      901 tccttataaa gtctgaattc ttatcaattt ggagtatatt agatatatcg aatatattaa
      961 gtatatgaag tatactaaat atatttagta taggaaattg gagggaacta tggaaaactt
     1021 acggactgca tttaaaacat cagataaact aggaaaagtt gtaatgctta caggtagaaa
     1081 aggcggcatt ggtaagacta cagacaatga tttattagcg attgtttcta gtcaactttt
     1141 tgaaaaagac gtgttgctaa ttgattatga ccaacaaaga aatactactt ccaacattgg
     1201 atcaacgtat caaattacta gctttgatcg atccatgtct gcagcaatca aaaaagggga
     1261 ctgggtttca ggtattactc aagtaagtcc acatttatat attatggctg gctctcctgg
     1321 atctgaagaa cttaatgaat acttgtccga aaaatatcct gatcgtcgta agagatcatt
     1381 ggccttcatt aaacctttag aagaattgag aaaaaatttc gattatatct ttatcgactg
     1441 cccaccatca acagataatg tggttcgtgc attcttaact gctgcagatt atattattgc
     1501 aatgcaagaa ttaaaacggt acgcaatgga aggaacagaa gattttatta ataaagtttt
     1561 agttccgatt gtcacgaatt ttgaagagtc tcatcttcaa atcattggaa ttttgcctgt
     1621 tcttttctca gtgcgacgtt cctctcaaca cgcaaactat caaaaaacaa ttgataagta
     1681 tggtgaatca aacattttta aaagcattgt taaaggctcg gatcggttag aaatgtatgg
     1741 tgagaatggt atccaattaa atgattatgt agatcgaaga tggtgggcta tttttgcaga
     1801 catctttaca gaattagaag aaagaattga atactatgaa caacatggtg atattgaagg
     1861 atttgattat acacctaaat atgctgactc aatggccaat catatcctac ctcttggaaa
     1921 ggagattaaa ctaaatggca ttattaccaa cgaacaaaga taagaagaaa attggtgctg
     1981 aagatatttc aattaaagat gatattaatg tcgagttagg ggaacgaaag tacactgcga
     2041 aagaaagaaa accagttcaa gtagatcctc ccgtactaaa aaccattcgg gatcttagtt
     2101 atgcaaaaga tattcctatg tatgaaatag tcaaacttgc aatggacgcc tatgttgata
     2161 ctttaaacga cgaggaacgg attatatata atagacgatc aaaagattaa aatatagtaa
     2221 gtatactaga tatagtaaat atatttagta tacttactat atttttagct ttattaatcc
     2281 taatccttca aaatatgtgt attgtttggg ggtatacaac attcacaaat tttattgttt
     2341 ctagttttta ctatactaaa tatatttaat atagtgagta tagtaaatat attggttttt
     2401 atctacaggt aatggtggtt ttaacaaaca tatagttaca gttactgaag aacagtccgt
     2461 tagtcagcag gagtaagtaa taaatcgttt gtgagacact attttgattg atacgacctc
     2521 taaccatgtg tttgtttcat ttatgttata ataagaatgt aagcatatta aacagcaaac
     2581 tatcacagca gcactagact caatcaaatg aagggggatg gtgctaatga aaaaactact
     2641 agcaatttcc cttatcctaa aaaggagaat taatagtgtc aaaagaacct atgtccgcat
     2701 ggatgcagct cgctcttagc atcataaagc tgatctctaa ttttgtggct ttagacaata
     2761 gagcaaaggt tctaactacg caatgtttag taatacttac ttgtagccta ctggttgtaa
     2821 tagtatttct tttacttgcg ttattcgtag tacacctttt gtttttttaa aacaaaagaa
     2881 gcttattcaa ctatatttag ctgaataagc tggtctcaat gttaaatcaa gtttgttgga
     2941 cgggtttaac attgctttct agtgctattt tagttagctc tagtatgctt caagctagtt
     3001 acaacgtcct aaggttgtaa ctagtttttt tatatttttt aattacctat aggtaatttt
     3061 atcagaattg atacaaaatg taaaacataa aagaaatata attttattgc actttaatag
     3121 ccaatatagt attcgtattt atggtatcct gctgcagctt ctacatagaa agagaagcgt
     3181 tcaacaccaa cctcatttat caaacgctgg ccataacccc aaatctcttc tgatagctga
     3241 tcaaaggtta tatactttag ctcatattgc tggataatgt tcattctaat cgaccccatt
     3301 tattatcctg gtaaaattcg atatgacgta tttcgtcgta gtgaactttg ttttttccaa
     3361 cgtagatccc cagctcatca ctacctaaga tcttgctaac aatatcttct ggatagtatc
     3421 cttcagcgtt tcgttcttct ttttgaatac atactgatct attttttatg actgcagcgt
     3481 tcaatacttc cgcaacctct tcagtcgtca tttgttcttt tgccaaattt tgattggctc
     3541 gttgttcatt gtcggcatca attttttcag tatgatcaga taaataaaaa cctgcccact
     3601 ttaaacgtcc acgatcatta taatcaatca tttttaagcc ctcctgcgcc gcctgcatgg
     3661 ccaccaacca atgtacttct agtaatacta cgagcgcctt ctaacataga agaagcatgt
     3721 acaatcgacg taaaaccata tttttgccga atcttgtcaa taattttatc taaattttct
     3781 tcgtcaattt gcttttgtgg atcactaaat aaatccagct gaagcgaatc agtgtacaca
     3841 agcttgctat aggttattcc aacgtgcctt acttcttgtc cttcataata cttatcaaac
     3901 aagaaaagac agtaattctg caattccttt gtattatctg ttatagggat cttcatctgg
     3961 tgtgaaaaac ctggtctcgt ttctaagatc gacgtgccaa tgtataaatg gacacaacct
     4021 gttttacagt tatgttgcct gatacgaata gctacttgtt ccgccatttc ttttaccacc
     4081 agttcgattt catttctcct ggtataatct cgtggtaaca cttgtgaatt accatatgat
     4141 ttttcctttg tcggttctgg tgggatcgct atatctgttc gatcgatccc gttcgcatga
     4201 aaatacagct gtaagccaat cacacctaaa tggctcttaa tagtgtatgg attccaatta
     4261 gctaagtctt taatactcat gataccaatt tggttgagtc tttttttcat tcgagatcca
     4321 ataccccaaa ggtctgtcat ttcaggaata ttccatactt tatcaggaac attttgatac
     4381 gtccattcag caaggaatcc atcattatgt tttgcttcat tgtctaaagc aagtttagct
     4441 aataagggat tatctccgac acctactgta gcaagcaatc ctagctcttc tttaatattc
     4501 tcctggatca tttgagccag cttctttctc cgttgacttc ttgttccttc agtcgtaaaa
     4561 agattcattg atctggtcac ttttaagatc gattcatcga tcgagtaaat caataaatct
     4621 tcgtctgcta cataccttct gaaaatattg tttacctgca tatttcgctt aatatagaga
     4681 ttcatgcgtg gtggaacgac atgtaacgtt ttaggaaaag gttgcggtag atctcgtggt
     4741 cgactgacat tagaaatacc gtacttcttc tttgcagctg gtgaagaagc taaaatcaac
     4801 cctgatcctg tattatccgc tcgactcatg acgactaatt cagtcgttaa tggatctaaa
     4861 ttcctttcta tacattcgac acttgcgtaa aagcttttca tatcgatcaa aaagtaatca
     4921 tttactggct cttttgaata atccatcata aataacactc cattcttcca cattatacaa
     4981 acatacgttc gtttttgtaa agaagaatcg attaaatgta caaaaaaaga agcataggta
     5041 agttatttcc ctacttcttc tgttgatttg taaaatcaac acattgtatc actttattaa
     5101 atggatattt actattagtc ttgtgaaaat ttgaaaataa gtgtcgtatt atccagtttt
     5161 gcttagttat attagaaaaa aataagaaat tcaaaaaaga aaaaactttc cttaaaaaca
     5221 aaaaatagga gtattcagtt tcttaatagt tttgtaatag ttgtatgtag aagttttctt
     5281 aatagttttt gtaataattt attaatcgta gtttatataa cttatttgta agtgactaga
     5341 gaattaaata aaaaataatt actatctagt acgaaattaa ttacatagga taatatatta
     5401 aggtgctgga ctacaagtaa aaaatactgt atgatcatga cagattcaag aaaggagcaa
     5461 taagattggt taagatagca ggactttcta aaggtggaaa aaccgtttca caactttata
     5521 aacaaaacta cagagactgg agacagttca gaaaaaacat taaggattct tactttattc
     5581 taccaacaga acttgaaaaa tatttaccga ataacaaagc tattaattta tatctgtatt
     5641 actgttttaa ggcaaagaat gaaggcgggg attcctggca ttcggtcaat accatagcag
     5701 agtctctagg agtgacaact aaaactataa acacctggaa taaaacctta gttgatttag
     5761 gtatgattgc acgtatagac gataaccatc tcagtaaatc gacaatttta cttcctctct
     5821 ctagttacta taaattagcc cttgatagtt ctttaaagga tgttaccgag agcactgtcc
     5881 atgaaattga tggcaacttg gttgcagttt atcatttgtt tgaatggaga aaaaatgagg
     5941 ctgatgaaaa ttataacgtt ccttataaca cactctgttg tgtttttaaa agaaaaacac
     6001 aaaaagatac tatctataaa tttatcttgg tccaagatga gaaaataagt aatttcgaat
     6061 taagcactcc ttctagtaag atttatgacg atgcatatag atttgaatgt caagatctag
     6121 aagccctcct ttccgcaaat aatctaaaca atatagaaca tgaaaacttt gttgtaaaca
     6181 ctagatttaa tttagtttct gaaaaggact cagatttgtt agatttgctg atagagctta
     6241 ctaaaaatct agataagaaa gaaaacatta ctgtactata actagcatcg gtccatcatt
     6301 aagtttggac tattagaaca cttgctatta cagaaaaagg tatgctagcc acgcttacta
     6361 tttattggta tcaaacaagt atcttaattt gaaaggaaga tgatttatgg ctaatttata
     6421 tatagagaac aaaggagact tgaatgccat tattacttta atcgtagtta tggtaaaatc
     6481 aataggtaat atcacaatag gaatgctgtt tattatatta gcagcagtgc tgatttttat
     6541 gatagttatt tggttcttaa atgaaagatc taaagacaat caacaccgta gggatatgga
     6601 gataaaatca atagagtcaa tagattattt atcgataata acactaaaaa agccacgttc
     6661 ctaaacgtga cttacgctga acgatatgtg ttgtttggta gacgaacaaa tcgttcatta
     6721 taaatatatg atggtatcct aatatagtaa gcgtggctag cataccttta attactttac
     6781 cttttacagt taccatacac attttttgag cagaaatcaa gtaaataaaa aaatattata
     6841 tttcacaaca tgctaataga ctcatatcta gaacgcatta agtatttacc tgtctggttc
     6901 gctgagactt cttttttaac tttcttcaat tttcttcttt attctaaaaa gcgtactgcg
     6961 actgaaaccg gttatagctt caacttcctt atacgattta cctgaagtaa gcagttcata
     7021 tgcgtgcctc ttcttcggtg tgattgttgc tttcggacgt ccttctctga aattaggatt
     7081 attctttctt gcaaacattt ttccttcttg ggtacgttcc acaatcatat cacgttccat
     7141 ttctgctaca ctcaacaacg tccgtgtcac cattcgcccc atggacgtat tttcaatcgt
     7201 tcctagattc aaaaccttga tcgttacgtt atcatcgagt aaaggttcaa tgatctctaa
     7261 tgcttctctc gtgttacgag caaatcgatc aagcttcgta acaactattt catctccagg
     7321 cttcagacca gccaacagct gattgaattt tggccgatcc cgttttgtac ccgtaaattt
     7381 ttctgaaaaa atattcttct tctctacgcc gttctcaagc aactgttgaa tttgttcttt
     7441 tgtactttga gaagcggttg agacacgtgc atatccatat ttcgtcattt ggtccaccta
     7501 cttttacaaa tcatctatcg tatactcaga atacccttca tagaaatagc tgacatcgat
     7561 tcctttcata tataactcgc gatcgtcaat tttatcagtc agagcattgg aaattagata
     7621 gcgtatttcc aaatcgttta tgggacttcg ctccattgca gaaagatagt ctgctttatc
     7681 gattaagttc caatctacaa ctttttgcaa ttcttccttt aaaatgagat ccagccaaat
     7741 tctagtactt cggccatttc cttctcgaaa tgggtgagcg atattcatct ccacatattt
     7801 cttgataatc tcttcaaaag aagtttgtgg catctgatca atatgctgta acgaatgttc
     7861 taaatacata actggtgcaa atcgaaaatt tccttttgca atattgaccg atcggatttt
     7921 tccggcaaaa tcgtaaatat ccgaaaatag aaattcatga atttcagata aacctttaaa
     7981 tgtaccaact tcgatttcat ttatttttcc acaatcgtac aattctttcg ctttttgttt
     8041 actgagtttt tcttcaacct tagccaactc aacttgattg gttaatccca atttattctc
     8101 taaaatcatg cgaaatctcc ttaactttat gacataagtt tatgaaacac tctcaacccc
     8161 attatatcgc gattttgttt atgtgtcaaa aactattaag tttctgaccc ccgatagatt
     8221 tttcaagtgt ctctattttg cacagtctag ttgacctttg atacacctct atatttatag
     8281 agaatctaaa acatcaacat ggcatactca aaattctaaa tattagggat aaagaattct
     8341 cctatacaat caaaaatttc ctttatttcg aactccggtc acctaactct attgatctct
     8401 tacaagccaa agaatatctc tatactacaa agaaacaata gggtgcctgg ttggtctctt
     8461 tgtgttttat tttagaatct agaacgtaaa tattcttgtc attctgattt tatctaagaa
     8521 tatcaattaa atcttttttt gcagcctctg aagcgggcat tacagaaaag accagtccaa
     8581 taaccgaaga taccccaacc gctagtaaaa tagtaaatag atcaagtgac acgtttacct
     8641 ttatcaaaga accaacacta taagcaagag ccattcctaa taaatagggt tctgttgcaa
     8701 agttttaaat aaagaataaa atcccttacg gtatctatga tttaagctgg gattcccaat
     8761 aataccttga tttcagtaca gaccgaaaac ccgaagagag tgccttcttt tcgggttttc
     8821 ttatataatc ctcgaatggc ttccatgcct ttaatcgtgg tagaggcagt gcgtaaactt
     8881 cgatagaatt tattgcgtct ctttactgga cgatggtctt gttcaatcaa attattcagg
     8941 tatttaatgg tacgatgttc tgtcccttga taaaagccgt attcttttag tttcttaaag
     9001 gcacttgtaa tagagggggc tttatctgtg actacaacct tcggttcatc aaactgcttc
     9061 actaaccgct taagaaaagc ataggctgct tgtgtgtccc gttttttacg taaccaaata
     9121 tccaaggtta aaccatctgc atcgatggct cgatacaaat aatgccattt tcctttaatt
     9181 ttgatgtacg tttcatccat tttccatgaa taaaaggatt ttttattttt ctttttccaa
     9241 atttgataga gtagtttgcc atattcttgc acccaacgat aaatcgtcgt atgagaaacg
     9301 ttaatgccac gatcatataa gatttcttga acttcacgat agctaaggtt ataacgaaga
     9361 tagtagccca cggctacaat aatcacatcc tgctgaaatt gctttccttt aaaaggattc
     9421 atcgtcattc ctcctgctat ctttttctat tattctacct tatttgatag tagatttaaa
     9481 actttgcaac agaaccaaaa ttttgtataa taggaattga agttaaatta gatgctaaaa
     9541 atttgtaatt aagaaggagg gattcgtcat gttggtattc caaatgcgta atgtagataa
     9601 aacatctacc gttttgaaac agactaaaaa cagtgattac gcagataaat aaatacgtta
     9661 gattaattcc taccagtgac taatcttatg actttttaaa cagataacta aaattacaaa
     9721 caaatcgttt aacttctgta tttatttata gatgtaatca cttcaggagt gattacatga
     9781 acaaaaatat aaaatattct caaaactttt taacgagtga aaaagtactc aaccaaataa
     9841 taaaacaatt gaatttaaaa gaaaccgata ccgtttacga aattggaaca ggtaaagggc
     9901 atttaacgac gaaactggct aaaataagta aacaggtaac gtctattgaa ttagacagtc
     9961 atctattcaa cttatcgtca gaaaaattaa aactgaacac tcgtgtcact ttaattcacc
    10021 aagatattct acagtttcaa ttccctaaca aacagaggta taaaattgtt gggaatattc
    10081 cttaccattt aagcacacaa attattaaaa aagtggtttt tgaaagccat gcgtctgaca
    10141 tctatctgat tgttgaagaa ggattctaca agcgtacctt ggatattcac cgaacactag
    10201 ggttgctctt gcacactcaa gtctcgattc agcaattgct taagctgcca gcggaatgct
    10261 ttcatcctaa accaaaagta aacagtgtct taataaaact tacccgccat accacagatg
    10321 ttccagataa atattggaag ctatatacgt actttgtttc aaaatgggtc aatcgagaat
    10381 atcgtcaact gtttactaaa aatcagtttc atcaagcaat gaaacacgcc aaagtaaaca
    10441 atttaagtac cgttacttat gagcaagtat tgtctatttt taatagttat ctattattta
    10501 acgggaggaa ataattctat gagtcgcttt tgtaaatttg gaaagttaca cgttactaaa
    10561 gggaatgtag ataaattatt aggtataggg cacctctaat aactaccaat taattcacct
    10621 caaaatgaaa ttagaaaaaa acagcgaaat ttttaaatct atttcttatc gatacaaatt
    10681 cctcgtaggc gctcgggacc ccaacatgag gaaatgtttt tataaaaaag agtagttacc
    10741 gttttttggt aactactctt ttcctttttt aaggtttaaa tacctggaag tttaggtgtt
    10801 ttgggtattg gtggtgtagg tagctgcaag ctttccattt tttgttgaat tgctttaaat
    10861 tcaggggttt cttggtgttg attttgaacc attttttgct ctattctctc caaagtcggt
    10921 tgaatttctt tccctgatac tttacgattt aattctcttt ctaaggtctc tttcggacta
    10981 atggaaggcg tttctaagct tgaatagagt ttcactcctt ctctattgta aagccttata
    11041 tcgctaaata agcccgtttt atgaagggtt tctaaattgg tcggtaagtt tttgacaaca
    11101 atatcatgcg cttgttttgg tgttgcccta gctgtcattg gatcatctgc atacatggtt
    11161 tcatatcgtt caatcgttcc taagtatgat tcaattttcg gtactgccat gacgtatatt
    11221 tttgtttcat aacctttaga ttgaagcatt gtggctgttt gaatgggaac gtctgttgtt
    11281 cgtcctgttc cttcaatcac taaattatag ccttgatcgc ttaaacggct aataagtgct
    11341 tctgtcatgc gattcgaata aggggtaacg tgttttacta cgtctttttc atagagtttc
    11401 actaattcgt caaaatttgg gtgctgttgt ttaaaggtat cattatcaat gacaataaca
    11461 ttcccttgtg tttcttcaaa aattgctgat cgcaaactgg ttttccctga ccctggttgc
    11521 ccaccaagta aaaaagcggt tggcgattca accgctagtc tatttttagt tagtcgttca
    11581 acattctttt ctaaacgatc ttcaaattgc ttttcggtga agtcagtaat attcgccatg
    11641 ttaagccact ttctctttat tcaaaatttg ttttgaatat tgattcattg accgccaata
    11701 ctcatgaata gcttgtaatt cttcaaatgg ttgttgaaat aaatcaactt cttgtgccac
    11761 ttctaattga tttaaaagat tcacttctag taaacgagta tttttagtat ctagttcatg
    11821 attcaaaaca taatttaata cccgattata aacacttgcc gataactcat taatgatttc
    11881 aatttcaaat gttttttcat acgtaactgc catttcattt tcactccttt taaagtttgt
    11941 caggtaaata tttccgtata tattcttcta aggcttgatc cataacttct tttacgtttc
    12001 cgccattctt tgctgtttcg atttttatga tatggtgcaa gtcggcacga acacgaaccg
    12061 tcttatcccc cattatatct ttttttgcgc tgattggcgt atcatttcgt tttgctttct
    12121 gtgcgcctaa atttcccacg atcgctcact tctttctatt tcttcttact atttatttta
    12181 tcatcaccta tcacaaatca caagtgattt gtgattctat tctttttcat tttctaattg
    12241 aatgattcgc tcaatcattt caaaaaatac gttctcatac atagacaaaa cttttttgtc
    12301 atagcctttg tgttctgtaa tgccattttt agaccaagta cttactttat tacttcgctt
    12361 gataatattt cggaaaacca aattatcctc tttatgttct ttgtacagtt cttccaggtt
    12421 tgattttatc gttgcgctgt ccgtatcaac taaataagga acaaaaccaa tcatatctag
    12481 tccagggtta aactgttctt gcaaatcaat caaataggaa atatagtttt gaatgttgtt
    12541 tgtactttct tcttctgctt gtaaagggat cataacgtaa tcactcgcca cgattgcatt
    12601 atttgtataa acgcttggcg ttggtacagt atcaataata ataagatcat agtcactttt
    12661 taaaggtgct aaaagagtag caagcaatct actttcattt tcaaacgtcc atgagcgagt
    12721 taattttggc agtaacatca aatcaaacgt gccagggatc aagtctaaat tatcagtcaa
    12781 atgaataata gaagaagcca agtttccatt tttcaagcct tcataaaaat tgacacgtgg
    12841 caattctacc tcaaaagttt ttgctaagtc ttttgtcaat gttgcctgta agtccttatc
    12901 gatcattaaa acttttaaat tcaatttgtc tgtcaagtaa gcaaacatag tcgataattt
    12961 ggactttcca acaccacctt taaagtaatt attcaagata ataattgctt catttttatt
    13021 gtttaaaata cgtcttaatt cttcaagtat ttttagtttt tccttctcca taactacgcc
    13081 ccattctttt tttgtatagt aatattgtat cattaagaat cacaaatcac aagtgatttg
    13141 tgattaatca cttgtgattt gtgataagtg atttgtgatt aatatataaa agccctcttt
    13201 aaagggcttt tataggttct gttgcaaagt tttaaataaa gaataaaatc ccttacggta
    13261 tctatgattt aagctgggat tcccaataat accttgattt cagtacagac cgaaaacccg
    13321 aagagagtgc cttcttttcg ggttttctta tataatcctc gaatggcttc catgccttta
    13381 atcgtggtag aggcagtgcg taaacttcga tagaatttat tgcgtctctt tactggacga
    13441 tggtcttgtt caatcaaatt attcaggtat ttaatggtac gatgttctgt tccttgataa
    13501 aagccgtatt cttttagttt cttaaaggca cttgtaatag agggggcttt atctgtgact
    13561 acaaccttcg gttcatcaaa ctgcttcact aaccgcttaa gaaaagcata ggctgcttgt
    13621 gtgtcccgtt ttttacgtaa ccaaatatcc aaggttaaac catctgcatc gatggctcga
    13681 tacaaataat gccattttcc tttaattttg atgtacgttt catccatttt ccatgaataa
    13741 aaggattttt tatttttctt tttccaaatt tgatagagta gtttgccata ttcttgcacc
    13801 caacgataaa tcgtcgtatg agaaacgtta atgccacgat catataagat ttcttgaact
    13861 tcacgatagc taaggttata acgaagatag tagcccacgg ctacaataat cacatcctgc
    13921 tgaaattgct ttcctttaaa aggattcatc gtcattcctc ctgctatctt tttctattat
    13981 tctaccttat ttgatagtag atttaaaact ttgcaacaga accgttcgtc acatcttcga
    14041 tcaatttctc ttacgatttt ctcatccaca tttcttattc ttacttccat attaattcct
    14101 ccaatttaaa aaggatagcg aaaaggagcc tatccttttt gctatcctac taccctcctt
    14161 ttactatcct tcactatcct ttcactatcc tatttttaaa tattttgttc ccacatttat
    14221 ttttgagaaa cgtaataggc acagcctatt ggaacacttt ttttaaaaag tgttcccacg
    14281 tttccttatg ctctttacaa ataaaggctt ttagagacgt tctggaattt tagattcctt
    14341 gaattgttcc cattcatcaa tcaattggct ataagtagcc attaattttt ttcttgctct
    14401 tgttgctttc gaatcaacaa aaaatcagtt tgattcgtta attctaaata ttctgttcgg
    14461 tattcaatgt tcatcgtacc cgttttacta catagtaact gattatgacg ttctttcact
    14521 ttgaataact gctccttctt taaggttttt aactccatgc caactataag cacaatcctg
    14581 tatagaggaa tcattttcaa acgattctcc ataattattt atctttcatt ggaagttcta
    14641 aatcactact gttccaaaaa atgtatggtt tgttttgacg aatattactt ccatctaacc
    14701 acaattttcc gatgccatat cgtaggcttg cttcgacttc ataaaaattg tagatctctt
    14761 ttcttcgatc tattgctttc atttcctggc cattttttaa aatagatctg atgcccttaa
    14821 cagtagattc atggatactc gtgtgaacga tatccgtatt gatcaattcg tcatatcttc
    14881 caaaatcaac attgtactca taaccaagaa gtgtcggaat caggtcaatt tcaatttctt
    14941 tttcaattga acgtttaata agtttcgtgg atacataccc gacaaaaaag agaataatac
    15001 ccacttcaaa caaatacatg tgtccattta caaagtgaat aaacgtcaat aaaaaatcct
    15061 tcactccttt tgttgttctt ccagattgtt caatttgttt tattaaagtc gctagaattg
    15121 catttacaac aattaaatcg aataggcttt tgaaaagttt tcctgctgtt aatttttgcc
    15181 tggtaaattg catgactaat tgagtaaaaa tagacaatag catgacaaaa atcaacgtca
    15241 ttagcactgt aaaaatgtct gatgctgcaa tcctattggg atcatttatc aagtaataag
    15301 ccgttccaaa tactccaatc gagtaaacgg ttaaatcaag aataagtcgt gccccgtaac
    15361 tacaaagttt tcctaatggc cataattgca atacccaaaa tttctttcgt ttgctatttc
    15421 ttttcagagg aagccaggtg tgttcaatcc agtcgtccga tttcatttcg atttcttccc
    15481 taaattcttt cctttaacgt tttcctttgc tactttagca gcgataggtt gctcaatgaa
    15541 ccaatttttt aagtaaataa aaactactac tggatatact tcttcctttt tcttaactcg
    15601 ttagctattt tatactcaat atactcctgc tctaacacac acaaacaatc atatacctga
    15661 tccatagtct ccccagaagc taaggacaac ccatgaagaa actcaatcgg caaagaagca
    15721 actgtttttt ccctggtaac ccaagaagac aaagtcccct gcttaaaacc ataaagctca
    15781 cagaacactt ccacagataa tcccaaacga ccaatgataa acacattaac aggatgtgaa
    15841 tagacataat tttttaacga catacaactt cctccatgat acataagact gcatacgcag
    15901 ttataagtat accacctaca cgtagctagg caaagggagc aacacctaca gaagtatcat
    15961 agatatattg tataaggcaa tttgcacctt ttatttttca acctgtatct acttcaaaaa
    16021 gattcacttc tttaagaggg ttcaaggggg ttgataattg tctaaatgtc tcttctacta
    16081 agctctcgtt gagtccaaat acctctgtga tccttgttga ataatctagt ctcttttctt
    16141 tacttagttg aataaccctc gcgaacaacg ttttgactga agcaatgatc attccgccat
    16201 ttcttcctcg tgttaccttg tagaagactt tattctcctc tcgtaactca tttaagatct
    16261 tatcaagtgt tcgcttgggc atcgttagtt gtgaagccaa ttcttttttt gacaggttca
    16321 aataaggctc actagcaaga cttttttcgc ttagataagc caatagatct tctttccatt
    16381 catttttatg actatatttt ctttgatctc gtggcttttt aaatttccac cagccacgtc
    16441 gttgaatgaa cagatcatta ttttttaagg ttggtgaaac ccattgctgg cacaattcaa
    16501 taatgaattc tctgcttgct gcttgataat taccagaata agcactacgt acaatcttta
    16561 ctaattctgc ttcagatagc ggttcctgta accgttcgtt gaatgtgaac atattgtatt
    16621 cgcaagtatc caatgcataa cctgaagagt aataagctaa agaaagcgtg aaaatcacat
    16681 tatttcgacc aagacgtcct tctccgccga cgatgtttgc tttatgaagt aacatatcga
    16741 accacggttc atctacttga cgaatttctt ttttctcagg aaagacaatt agttttcgtt
    16801 ctcgatcttc ttttgttttt tgatctgatt caagcttcat cgaccattga atccagtcag
    16861 caaaagaata ctgatagttc atttctttaa aaacaatatt attttcttgt gggaatcgag
    16921 caattccgaa gtggttacat cctagatcca ctccggacaa tttttcagcc aactgtagac
    16981 gaattgtttt tgaaattttt tttgctacat cgatcacctt gaaattgctt ttctttgtga
    17041 catagcctgg tgtctttagt acaaaataaa cttgataacc atgatctgat tct
//
