LOCUS       CP061252                7135 bp    DNA     circular BCT 13-JAN-2022
DEFINITION  Escherichia coli strain STEC399 plasmid pSTEC399_2, complete
            sequence.
ACCESSION   CP061252
VERSION     CP061252.1
DBLINK      BioProject: PRJNA655129
            BioSample: SAMN15748002
KEYWORDS    .
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7135)
  AUTHORS   Pan,Y., Xiong,Y. and Yang,X.
  TITLE     Genomic characteristics of Shiga toxin-producing Escherichia coli
            (STEC)
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7135)
  AUTHORS   Pan,Y., Xiong,Y. and Yang,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2020) National Institute for Communicable Disease
            Control and Prevention, Chinese Center for Disease Control and
            Prevention, No. 155, Changbai Rd, Beijing 102200, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. v. 4
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 09/02/2020 12:37:58
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 4.12
            Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,036
            Genes (coding)                    :: 3,925
            CDSs (with protein)               :: 3,925
            Genes (RNA)                       :: 123
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 91
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 1,111
            CDSs (without protein)            :: 1,111
            Pseudo Genes (ambiguous residues) :: 0 of 1,111
            Pseudo Genes (frameshifted)       :: 1,022 of 1,111
            Pseudo Genes (incomplete)         :: 103 of 1,111
            Pseudo Genes (internal stop)      :: 65 of 1,111
            Pseudo Genes (multiple problems)  :: 74 of 1,111
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..7135
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="STEC399"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /plasmid="pSTEC399_2"
                     /geo_loc_name="China: Henan"
                     /collection_date="2013"
     gene            complement(join(7027..7135,1..1383))
                     /gene="csa"
                     /locus_tag="H6S15_25745"
                     /pseudo=""
     CDS             complement(join(7027..7135,1..1383))
                     /gene="csa"
                     /locus_tag="H6S15_25745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_104355618.1"
                     /note="frameshifted; incomplete; partial on complete
                     genome; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="pore-forming bacteriocin colicin S4"
                     /name="csa"
     gene            1622..1912
                     /locus_tag="H6S15_25750"
     CDS             1622..1912
                     /locus_tag="H6S15_25750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001672407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UIV26898.1"
                     /translation="MSKSPRHKLNKTDKRLLDTLVAAGYEHDKARDLIQKQVYTLTLAD
                     QRHVVSEISNGVNPTQAYSAVYQARRIRLARKYLNGKKVMEETGENTPPST"
                     /name="hypothetical protein"
     gene            complement(1904..2182)
                     /locus_tag="H6S15_25755"
     CDS             complement(1904..2182)
                     /locus_tag="H6S15_25755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UIV26899.1"
                     /translation="MKKCVPVLLFSVLSASVASHADSNVFQQKAEKTKNGIVADVNARQ
                     KMFSNRLKIQLQIDELRAELAGTRDAQKREDLRKKLESLERQKKSLR"
                     /name="hypothetical protein"
     gene            2304..2726
                     /gene="exc2"
                     /locus_tag="H6S15_25760"
     CDS             2304..2726
                     /gene="exc2"
                     /locus_tag="H6S15_25760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001255518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Exc2 family lipoprotein"
                     /protein_id="UIV26900.1"
                     /translation="MRSAATRLLLIPLITATIALTGCTPKTSLERHTRHYVYASDDGFD
                     PNFYTQKADTIRMMLPFFQQFRDMGMKDKAAGVSAETAQQRAKEFHSEKFFHSLQSTTT
                     FAGRKYTNSDMPSLKKMKLMADTISAVYLDGYEGRQ"
                     /name="exc2"
     gene            complement(3209..3442)
                     /gene="mbeD"
                     /locus_tag="H6S15_25765"
     CDS             complement(3209..3442)
                     /gene="mbeD"
                     /locus_tag="H6S15_25765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeD family mobilization/exclusion protein"
                     /protein_id="UIV26901.1"
                     /translation="MTELEMHLLNALEQLQQDYTQRLKDWESAFTDLQHMFELTRQENG
                     QLREQCDDLSQQVQRLAGQVDRLSRLFITNSR"
                     /name="mbeD"
     gene            complement(3449..4009)
                     /locus_tag="H6S15_25770"
     CDS             complement(3449..4009)
                     /locus_tag="H6S15_25770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeB family mobilization protein"
                     /protein_id="UIV26902.1"
                     /translation="MSNLLQMGTDFEKKLKERAVSTENMLNSEFRKLEASVDRELNLNG
                     QKIRDAISAHTAAVKEQLETLNSAVNAQFSATENELARRQEELLWKLIKGRILYPSLTA
                     LCVTGGIFLASWGLIQWQESRIAANILAIRDQEETLAKLREKTWGVTYHEGRNGKFLVL
                     PSGVKGENNWTVEKKNAVRLVRE"
                     /name="MbeB family mobilization protein"
     gene            complement(3981..4724)
                     /locus_tag="H6S15_25775"
                     /pseudo=""
     CDS             complement(3981..4724)
                     /locus_tag="H6S15_25775"
                     /inference="COORDINATES: protein motif:HMM:NF015397.1"
                     /note="incomplete; partial on complete genome; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /name="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            complement(4687..5010)
                     /locus_tag="H6S15_25780"
     CDS             complement(4687..5010)
                     /locus_tag="H6S15_25780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="UIV26903.1"
                     /translation="MLTIRVTDEEHARLLARCEGKQLASWMRKVCLGAPPSKTSGLPTL
                     APPLLRQFASVGNNLNQIARKINSGQWSGHDRVHVVAALMAIGRELSELRDEVRKQGER
                     DDS"
                     /name="MobC family plasmid mobilization relaxosome protein"
     gene            5078..5269
                     /locus_tag="H6S15_25785"
     CDS             5078..5269
                     /locus_tag="H6S15_25785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="UIV26895.1"
                     /translation="MTKQEKTALNMARFIRSQTLTLLEKLNELDVDDQADICEALHDHA
                     DELYRSCLAHFGDDGENL"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            complement(6267..6422)
                     /gene="csl"
                     /locus_tag="H6S15_25790"
     CDS             complement(6267..6422)
                     /gene="csl"
                     /locus_tag="H6S15_25790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_071703583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin S4 system lysis protein"
                     /protein_id="UIV26896.1"
                     /translation="MKKIIICAISLGIMLLAACQVNNVRDTGGGAVSPSSTVTGVSMGS
                     GGSGSL"
                     /name="csl"
     gene            6452..6991
                     /gene="csi"
                     /locus_tag="H6S15_25795"
     CDS             6452..6991
                     /gene="csi"
                     /locus_tag="H6S15_25795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_104355619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin S4 immunity protein"
                     /protein_id="UIV26897.1"
                     /translation="MMIDEHSIDIDNRKANNLLYLFMVIGVIPLLCILAVYYTNPDNLF
                     LHTIATSTENIPSITSAYNPLMTKVMDIYCKTAPSLALILFILTFKTRKLIKKTNRNAV
                     LRSCLLSPFVCAVFLYLLCFRNLELTTAGRPARLMTNNDATLLLFYIGLYLIIFFISYF
                     TLFTPVTTFKLLKERQ"
                     /name="csi"
     Typing          complement(5356..5442)
                     /name="MOBP"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="98.864"
                     /coverage="99.0"
                     /evalue="1.15e-36"
     Typing          5466..6010
                     /name="rep_cluster_2350"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.796"
                     /coverage="99.0"
                     /evalue="0.0"
     Typing          complement(3103..4697)
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="99.248"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(5070..5272)
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="86.765"
                     /coverage="100.0"
                     /evalue="1.39e-10"
ORIGIN
        1 ccaagagata aggcatatgc ccctaatgtg gctgaaaaaa cacccagggc cacagcagaa
       61 gcgatgccac tgagcaccca ggactccacc tccagcatca gaggtcccca gttcccggtt
      121 tcatagccct cgatgctttt ctcccggacc ttctcaacct tcatcaccac atcggcaaat
      181 ttgaaagcct tgctgatatt acccagttta tttgccatat cctgagcatc aatacttcgc
      241 cagacgttcg ccagtgcatc actgtcggcc ctgttaaatt taaaccccgg attagacaaa
      301 actttattta atgacgccat tgcatcatcg tagctacgga tagttttccc ctggaaattt
      361 ttgacatcat cagcaatttc tcttgctaac gacttataat catctccaag ataatcaccg
      421 accttattac ctatatcaga gataacttca gcggctttat taagtacatc actctgaatc
      481 cggtcacggt tcatactgaa agaataaaac acatcataag cagctttttt agcttgatcc
      541 tgtcgttgag gctcttcatt attaaatcct aatgcctcat atatctcttc cggggtctta
      601 tggtcgactt tatccataat accagcctta gctttttcac tccctacata aggacgaaca
      661 gctgttctag ttacagataa aacattacca taatcatcaa gcaccactaa atagtggaac
      721 tgttcaacat caacatcaaa ttttctcaca ttaggaggca aacgatccca cgcatcttca
      781 gcctgttgtt ttgctttttc ctgccgctga gattcatctt tattaaaacc taacgcctca
      841 tatatctcct caggagtttt atgattgatt ttttccataa tacccgcctt agctttttca
      901 ctccctacgt aaggacggac acctgttcga agaataccga tagctctacc attatcatta
      961 agcgttacac gatatttaaa accatcgata ctcacatcaa tctctcgcgg taagttgttt
     1021 tttatcccac ttacgagcaa cttcatcatt aggattttca gggatatagc ccccctgaac
     1081 atcactattt ccgccagccc caggaactcc atatacaggc gtttttacca gaccatttgt
     1141 gatggtaatg cgcacctgcc cattatcatc aacataaggc ggcacatccg gattattggt
     1201 tttactccat ccccaccccg tctgacttcc atgttcacga cctccattac cagagcctga
     1261 accaccaccc cagtgaaccc cactattact attattattt ccaccttgct gattcagatt
     1321 cgcccctgtt ccccccatag actcaccagc agttgggcca tatccactta gttctttagc
     1381 cataaattcc tctttgataa ttaaaacaat aaattaaaaa cagtatactg tacatataac
     1441 cactggtttt atgtacagca aaacctacta ctcaccattg tccatgtcaa gagcatggat
     1501 tttcattttt gctataagga tcacgctatg gggaggcagg cattgagaac gtcgaaacag
     1561 aacaccggag caaatcagga tgagatataa aactgttgga tcatgaaaaa cggagaacga
     1621 tgtgagcaaa tcaccccgcc ataaactgaa caaaacagac aaacgacttc tcgacaccct
     1681 tgttgctgcc ggatatgagc atgacaaagc ccgtgacctc atccagaaac aggtttacac
     1741 gctgacactg gctgatcagc gtcatgtggt cagtgaaatc agtaatggtg tgaatcccac
     1801 ccaggcttac tcggcggtat accaggcaag acgcattcgc ctcgcccgta aatatctgaa
     1861 cggtaaaaag gttatggaag aaaccgggga aaatacgccc ccatcaacgt aaggatttct
     1921 tttgccgctc cagagactcc agttttttac gcaaatcctc tcttttttgg gcatctctgg
     1981 tgccagccag ctctgctctc aactcatcga tctgaagttg tatcttcagt ctgttactga
     2041 acattttctg tctggcatta acatccgcaa caatgccgtt ttttgtcttc tcggcctttt
     2101 gttgaaaaac attgctgtcc gcatgactgg caaccgaagc agaaagaaca ctaaaaagca
     2161 ggactggcac acattttttc acgggattat tcctgactca ttgaccatca aatcacattg
     2221 ggagtaaacc gacgtatgat aagagatact cttcggagat ataactccct gagtatcaag
     2281 attaaaaacg caaggagatg tttatgagat ctgccgctac caggctgctt ctgatacctc
     2341 tgataacagc aacaatagct cttacaggat gcaccccaaa gaccagcctg gaacgacata
     2401 cccgacatta tgtttatgct tcagatgatg gatttgatcc taacttctat acccagaaag
     2461 cagacaccat acgtatgatg ctcccgttct ttcagcagtt ccgggatatg gggatgaaag
     2521 acaaagcagc cggagtatca gcagaaacgg cacagcaacg tgcaaaagaa ttccactcag
     2581 aaaaattttt tcactcactc cagagcacaa caacctttgc tggcagaaaa tacacaaaca
     2641 gcgatatgcc ttcgctgaaa aaaatgaaac taatggcaga caccatttct gcggtttatc
     2701 tcgatggata cgagggcaga cagtaaggga tttaccataa tcccttaatt gtacgcaccg
     2761 ctgaaatgcg ttcagcgcga tcacggctgc tgacaggtaa aaatggcaac aaaccacccg
     2821 aaaagctgcc gcgatcgcac ctgataaatt ttaaccgtat gcatagctat tcagccatgt
     2881 gaataacgct ggttttgcct gcgtaaacct catgacactg tttttttcca tcttttcagt
     2941 tgatgacata cgcagacatc gcgggatgag gctgaggaat gagcgcgatc tggcaaagag
     3001 gcaaaacaca gcaacaaaaa cgacactcca gaatcgcgcc cggatgcgtt tttaacgcgt
     3061 tccggtacca tctggcaacc tcccggaaca actcaccgtc acatccccat tgacgggcca
     3121 cgccataccc gtgcttcccg ttcctgctct tcatgccagg accgcgcacg ctcccgttcc
     3181 aggcgtgcct gcctttcctg ttcatccctt atctgctgtt cgtgataaat aaccgactca
     3241 agcggtccac ctgcccggct aatctctgca cctgctgact caagtcgtcg cactgttccc
     3301 tcagttgccc gttctcctgt cgtgtcagct cgaacatatg ctgcaaatcc gtgaaggcgc
     3361 tctcccagtc tttcagccgc tgcgtatagt cctgctgcaa ttgctctaag gcgttcagta
     3421 agtgcatttc cagctctgtc atactcactt actccctgac cagtcttact gcgttcttct
     3481 tctccaccgt ccagttgttt tcccccttca ccccggacgg cagcaccaga aatttcccgt
     3541 tcctgccctc gtgatacgtc acaccccatg ttttttcccg gagtttcgcc agcgtctctt
     3601 cctggtccct gatagccagg atgttcgccg caatccggct ttcctgccac tgaatcagcc
     3661 cccatgacgc cagaaaaatc ccgcccgtga cgcaaagcgc cgtcagcgac gggtacagta
     3721 tccgcccttt gatcagcttc cagagcagct cttcctgccg ccgggccagt tcgttctctg
     3781 tggcgctgaa ctgcgcgttc acggcactgt tcagcgtctc cagttgttct ttcaccgctg
     3841 ctgtgtgtgc gctgatagcg tctctgattt tctgcccgtt taagttcagt tccctgtcta
     3901 cagacgcttc gagcttcctg aactcgctgt tcagcatgtt ctctgtagag acggcacgct
     3961 ctttcagttt cttctcgaag tctgtcccca tttgtaaaag attgctcata cagcgcccct
     4021 ttcagcctga gattacgccc gccctccggg tcggcgatac tgatactgct cctggttgtc
     4081 ctcacaacct caaaacctgc cgctgtaagc gcctcagtga catcctgacg cgtttttagc
     4141 gctccggcat ggtaaagagc ctccagtccc ctcgtaatcg cttctgcggc ctcctgtttc
     4201 gctttcggca gattattcgg ggtgacaagt gtccgcctgt tctccggtgc gttcgggtcg
     4261 tgcagcccgt aatggtgatt caccagtgtc tgccaggcat tgattcgcgg acggtccgcc
     4321 cggtcgtaat agggctggag ccgttttccg ctcgccagct ccatattcgg gatgacaaaa
     4381 ttcagctcaa gacgcccctt gtcctggtgc tccacccaca ggatgctgta ctgatttttt
     4441 tcaagaccgg gcatcagtac ccgctcaaag ctctccatca ccctttcacg ctctcccggt
     4501 ggcagggtct gctctgcaaa agacagaacc cccgaggtgt attttttcgc aaacggcgtg
     4561 gcatcgatga gttcccgtac ctcttcggga gcaccccgca gaactctcac cccttcccgg
     4621 ttacgctccc ggcccagcag gtaatcaacc ggaccactgc caccgccttt tcccctggca
     4681 tgaaacttaa ctatcatccc gttctccctg tttacggacc tcatccctaa gctcactcag
     4741 ttcacgtccg atggccatca gtgcagccac cacatgaacc cggtcatgcc ccgaccactg
     4801 tccgctgttt atcttccggg ctatctgatt caggttattg ccgaccgaag cgaactggcg
     4861 caacagcggc ggtgccagtg tcggaagacc tgacgttttc gatggcggtg cccccaggca
     4921 gaccttacgc atccatgacg caagttgttt tccctcacaa cgtgccagca gccgcgcatg
     4981 ttcctcatcc gtgacccgta tcgtgagcat cctttcgcgt ttcaccggta tcattaaaaa
     5041 cctccgacag actccccaca catggagaaa cagaactgtg actaaacagg aaaaaaccgc
     5101 ccttaacatg gcccgcttca tcagaagcca gacgctgacc ctgctggaaa aactgaatga
     5161 actggacgtc gacgaccagg ctgacatctg cgaagcgctt cacgaccacg ctgacgagct
     5221 ttaccgcagc tgcctcgcac acttcgggga tgacggtgaa aacctctgac acatgcagct
     5281 cccggagacg gtcacagctg gcctgtgagc ggatgccggg agcagacaag cccgtcaggg
     5341 cgcgtcagcg ggtgttagcg ggtgtcgggg cgcagccatg acccagtcac gtagcgatag
     5401 cggagtgtat actggcttaa tcatgtggca tcagtgagga ttgtatgaaa agtgcaccat
     5461 gccgggtgtg aaatgccgca cagatgcgta aggagaaaat gctcgtccgg gcacttttcc
     5521 gcttcctcgc tcactgactc gctgcgctcg gtcgttcgac tgcggcgagc ggagtctgct
     5581 tgctcaaaaa cggcgatacg gttatccaca gaatcagggg ataaggcaga aaagaacatg
     5641 tgagcaaaaa ggcaaagggc aaaaaaagcc gcgtcgctgg cgtttttcca taggctccgc
     5701 ccccctgacg agcatcacaa aaatcgacgc tcaagtcaga ggtggcgaaa cccgacagga
     5761 ctataaagat accaggcgtt tccccctgga agctccctcg tgcgctctcc tgttccgacc
     5821 ctgccgctta ccggatacct gtccgccttt ctcccttcgg gaagcgtggc gctttctcat
     5881 agctcacgct gttggtatct cagttcggtg taggtcgttc gctccaagct gggctgtgtg
     5941 cacgaacccc ccgttcagcc cgaccgctgc gccttatccg gtaactatcg tctcgagtcc
     6001 accccggtaa gacacgacaa agcgccactg gcagcagcca ttggtaactg aaaagtggat
     6061 ttagatacgc agaactcttg aagttgaagc cttatagcgg ctacactgaa aggacagcat
     6121 ttggtatctg tgctccactt aagccagcta cccggttaag cagtccccaa ctgacttaac
     6181 cttcgactaa accgcctccc caggcggttt tttcgtttac agggcaagag actacgacga
     6241 tctgtaaagg atctcaagaa gatcctttac aggctaccac taccaccact tcccatactc
     6301 actccggtaa cagtggaaga tggtgaaaca gccccacctc cagtatctct gacattgttg
     6361 acttggcatg ctgcaagcag cattattcct agtgaaatgg cacaaataat aatttttttc
     6421 atatatacct ttattataat cctataggtc aatgatgatt gatgaacatt caatagatat
     6481 agacaataga aaagccaata acttattgta tttatttatg gtaatcggag ttataccttt
     6541 actctgtata ctagccgttt actatacaaa tccagacaat ctgttcttgc acacaatagc
     6601 taccagtact gaaaacatcc catcaataac ctccgcctac aacccattaa tgacaaaggt
     6661 tatggatatt tattgtaaaa cagcgccttc ccttgctttg atattattta tcctgacatt
     6721 taaaacgaga aagctaataa aaaaaacaaa ccgaaatgct gtacttagaa gttgcttatt
     6781 aagtccattt gtctgtgctg tttttttgta tttactctgt ttccgaaacc ttgagctaac
     6841 gacagcagga aggccagcca ggctaatgac caacaatgat gcaacactat tgctatttta
     6901 tattggcctg tacttaatca tttttttcat aagctatttc acgctattca caccagttac
     6961 cacgtttaaa ttattaaaag aaaggcagta accctgcctt ccttttaccc ggtatttatt
     7021 aatgcgcggt ttaatgattt ctttatttag tgcatctgca aacttgtcat caattaatgc
     7081 acctacaact gctgcgagta gaatacctac gataccgaca gcaatagcag gagcc
//
