LOCUS       CP061219                7135 bp    DNA     circular BCT 13-JAN-2022
DEFINITION  Escherichia coli strain STEC405 plasmid pSTEC405_2, complete
            sequence.
ACCESSION   CP061219
VERSION     CP061219.1
DBLINK      BioProject: PRJNA655129
            BioSample: SAMN15748006
KEYWORDS    .
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7135)
  AUTHORS   Pan,Y., Xiong,Y. and Yang,X.
  TITLE     Genomic characteristics of Shiga toxin-producing Escherichia coli
            (STEC)
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7135)
  AUTHORS   Pan,Y., Xiong,Y. and Yang,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (31-AUG-2020) National Institute for Communicable Disease
            Control and Prevention, Chinese Center for Disease Control and
            Prevention, No. 155, Changbai Rd, Beijing 102200, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. v. 4
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 09/02/2020 11:53:03
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 4.12
            Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region
            Genes (total)                     :: 5,109
            CDSs (total)                      :: 4,986
            Genes (coding)                    :: 4,847
            CDSs (with protein)               :: 4,847
            Genes (RNA)                       :: 123
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 91
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 58 of 139
            Pseudo Genes (incomplete)         :: 67 of 139
            Pseudo Genes (internal stop)      :: 41 of 139
            Pseudo Genes (multiple problems)  :: 23 of 139
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..7135
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /strain="STEC405"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /plasmid="pSTEC405_2"
                     /geo_loc_name="China: Henan"
                     /collection_date="2013"
     gene            complement(join(6199..7135,1..563))
                     /gene="csa"
                     /locus_tag="H6S19_25495"
     CDS             complement(join(6199..7135,1..563))
                     /gene="csa"
                     /locus_tag="H6S19_25495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_104355618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pore-forming bacteriocin colicin S4"
                     /protein_id="UIV09032.1"
                     /translation="MAKELSGYGPTAGESMGGTGANLNQQGGNNNSNSGVHWGGGSGSG
                     NGGREHGSQTGWGWSKTNNPDVPPYVDDNGQVRITITNGLVKTPVYGVPGAGGNSDVQG
                     GYIPENPNDEVARKWDKNNLPREIDVSIDGFKYRVTLNDNGRAIGILRTGVRPYVGSEK
                     AKAGIMEKINHKTPEEIYEALGFNKDESQRQEKAKQQAEDAWDRLPPNVRKFDVDVEQF
                     HYLVVLDDYGNVLSVTRTAVRPYVGSEKAKAGIMDKVDHKTPEEIYEALGFNNEEPQRQ
                     DQAKKAAYDVFYSFSMNRDRIQSDVLNKAAEVISDIGNKVGDYLGDDYKSLAREIADDV
                     KNFQGKTIRSYDDAMASLNKVLSNPGFKFNRADSDALANVWRSIDAQDMANKLGNISKA
                     FKFADVVMKVEKVREKSIEGYETGNWGPLMLEVESWVLSGIASAVALGVFSATLGAYAL
                     SLGAPAIAVGIVGILLAAVVGALIDDKFADALNKEIIKPAH"
                     /name="csa"
     gene            802..1092
                     /locus_tag="H6S19_25500"
     CDS             802..1092
                     /locus_tag="H6S19_25500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001672407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UIV09033.1"
                     /translation="MSKSPRHKLNKTDKRLLDTLVAAGYEHDKARDLIQKQVYTLTLAD
                     QRHVVSEISNGVNPTQAYSAVYQARRIRLARKYLNGKKVMEETGENTPPST"
                     /name="hypothetical protein"
     gene            complement(1084..1362)
                     /locus_tag="H6S19_25505"
     CDS             complement(1084..1362)
                     /locus_tag="H6S19_25505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UIV09034.1"
                     /translation="MKKCVPVLLFSVLSASVASHADSNVFQQKAEKTKNGIVADVNARQ
                     KMFSNRLKIQLQIDELRAELAGTRDAQKREDLRKKLESLERQKKSLR"
                     /name="hypothetical protein"
     gene            1484..1906
                     /gene="exc2"
                     /locus_tag="H6S19_25510"
     CDS             1484..1906
                     /gene="exc2"
                     /locus_tag="H6S19_25510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001255518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Exc2 family lipoprotein"
                     /protein_id="UIV09035.1"
                     /translation="MRSAATRLLLIPLITATIALTGCTPKTSLERHTRHYVYASDDGFD
                     PNFYTQKADTIRMMLPFFQQFRDMGMKDKAAGVSAETAQQRAKEFHSEKFFHSLQSTTT
                     FAGRKYTNSDMPSLKKMKLMADTISAVYLDGYEGRQ"
                     /name="exc2"
     gene            complement(2389..2622)
                     /gene="mbeD"
                     /locus_tag="H6S19_25515"
     CDS             complement(2389..2622)
                     /gene="mbeD"
                     /locus_tag="H6S19_25515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeD family mobilization/exclusion protein"
                     /protein_id="UIV09036.1"
                     /translation="MTELEMHLLNALEQLQQDYTQRLKDWESAFTDLQHMFELTRQENG
                     QLREQCDDLSQQVQRLAGQVDRLSRLFITNSR"
                     /name="mbeD"
     gene            complement(2629..3189)
                     /locus_tag="H6S19_25520"
     CDS             complement(2629..3189)
                     /locus_tag="H6S19_25520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeB family mobilization protein"
                     /protein_id="UIV09037.1"
                     /translation="MSNLLQMGTDFEKKLKERAVSTENMLNSEFRKLEASVDRELNLNG
                     QKIRDAISAHTAAVKEQLETLNSAVNAQFSATENELARRQEELLWKLIKGRILYPSLTA
                     LCVTGGIFLASWGLIQWQESRIAANILAIRDQEETLAKLREKTWGVTYHEGRNGKFLVL
                     PSGVKGENNWTVEKKNAVRLVRE"
                     /name="MbeB family mobilization protein"
     gene            complement(3161..3904)
                     /locus_tag="H6S19_25525"
                     /pseudo=""
     CDS             complement(3161..3904)
                     /locus_tag="H6S19_25525"
                     /inference="COORDINATES: protein motif:HMM:NF015397.1"
                     /note="incomplete; partial on complete genome; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /name="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            complement(3867..4190)
                     /locus_tag="H6S19_25530"
     CDS             complement(3867..4190)
                     /locus_tag="H6S19_25530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="UIV09028.1"
                     /translation="MLTIRVTDEEHARLLARCEGKQLASWMRKVCLGAPPSKTSGLPTL
                     APPLLRQFASVGNNLNQIARKINSGQWSGHDRVHVVAALMAIGRELSELRDEVRKQGER
                     DDS"
                     /name="MobC family plasmid mobilization relaxosome protein"
     gene            4258..4449
                     /locus_tag="H6S19_25535"
     CDS             4258..4449
                     /locus_tag="H6S19_25535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="UIV09029.1"
                     /translation="MTKQEKTALNMARFIRSQTLTLLEKLNELDVDDQADICEALHDHA
                     DELYRSCLAHFGDDGENL"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            complement(5447..5602)
                     /gene="csl"
                     /locus_tag="H6S19_25540"
     CDS             complement(5447..5602)
                     /gene="csl"
                     /locus_tag="H6S19_25540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_071703583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin S4 system lysis protein"
                     /protein_id="UIV09030.1"
                     /translation="MKKIIICAISLGIMLLAACQVNNVRDTGGGAVSPSSTVTGVSMGS
                     GGSGSL"
                     /name="csl"
     gene            5632..6171
                     /gene="csi"
                     /locus_tag="H6S19_25545"
     CDS             5632..6171
                     /gene="csi"
                     /locus_tag="H6S19_25545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_104355619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin S4 immunity protein"
                     /protein_id="UIV09031.1"
                     /translation="MMIDEHSIDIDNRKANNLLYLFMVIGVIPLLCILAVYYTNPDNLF
                     LHTIATSTENIPSITSAYNPLMTKVMDIYCKTAPSLALILFILTFKTRKLIKKTNRNAV
                     LRSCLLSPFVCAVFLYLLCFRNLELTTAGRPARLMTNNDATLLLFYIGLYLIIFFISYF
                     TLFTPVTTFKLLKERQ"
                     /name="csi"
     Typing          complement(4536..4622)
                     /name="MOBP"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="98.864"
                     /coverage="99.0"
                     /evalue="1.15e-36"
     Typing          4646..5190
                     /name="rep_cluster_2350"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.796"
                     /coverage="99.0"
                     /evalue="0.0"
     Typing          complement(2283..3877)
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="99.248"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(4250..4452)
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="86.765"
                     /coverage="100.0"
                     /evalue="1.39e-10"
ORIGIN
        1 ttattaaaac ctaacgcctc atatatctcc tcaggagttt tatgattgat tttttccata
       61 atacccgcct tagctttttc actccctacg taaggacgga cacctgttcg aagaataccg
      121 atagctctac cattatcatt aagcgttaca cgatatttaa aaccatcgat actcacatca
      181 atctctcgcg gtaagttgtt tttatcccac ttacgagcaa cttcatcatt aggattttca
      241 gggatatagc ccccctgaac atcactattt ccgccagccc caggaactcc atatacaggc
      301 gtttttacca gaccatttgt gatggtaatg cgcacctgcc cattatcatc aacataaggc
      361 ggcacatccg gattattggt tttactccat ccccaccccg tctgacttcc atgttcacga
      421 cctccattac cagagcctga accaccaccc cagtgaaccc cactattact attattattt
      481 ccaccttgct gattcagatt cgcccctgtt ccccccatag actcaccagc agttgggcca
      541 tatccactta gttctttagc cataaattcc tctttgataa ttaaaacaat aaattaaaaa
      601 cagtatactg tacatataac cactggtttt atgtacagca aaacctacta ctcaccattg
      661 tccatgtcaa gagcatggat tttcattttt gctataagga tcacgctatg gggaggcagg
      721 cattgagaac gtcgaaacag aacaccggag caaatcagga tgagatataa aactgttgga
      781 tcatgaaaaa cggagaacga tgtgagcaaa tcaccccgcc ataaactgaa caaaacagac
      841 aaacgacttc tcgacaccct tgttgctgcc ggatatgagc atgacaaagc ccgtgacctc
      901 atccagaaac aggtttacac gctgacactg gctgatcagc gtcatgtggt cagtgaaatc
      961 agtaatggtg tgaatcccac ccaggcttac tcggcggtat accaggcaag acgcattcgc
     1021 ctcgcccgta aatatctgaa cggtaaaaag gttatggaag aaaccgggga aaatacgccc
     1081 ccatcaacgt aaggatttct tttgccgctc cagagactcc agttttttac gcaaatcctc
     1141 tcttttttgg gcatctctgg tgccagccag ctctgctctc aactcatcga tctgaagttg
     1201 tatcttcagt ctgttactga acattttctg tctggcatta acatccgcaa caatgccgtt
     1261 ttttgtcttc tcggcctttt gttgaaaaac attgctgtcc gcatgactgg caaccgaagc
     1321 agaaagaaca ctaaaaagca ggactggcac acattttttc acgggattat tcctgactca
     1381 ttgaccatca aatcacattg ggagtaaacc gacgtatgat aagagatact cttcggagat
     1441 ataactccct gagtatcaag attaaaaacg caaggagatg tttatgagat ctgccgctac
     1501 caggctgctt ctgatacctc tgataacagc aacaatagct cttacaggat gcaccccaaa
     1561 gaccagcctg gaacgacata cccgacatta tgtttatgct tcagatgatg gatttgatcc
     1621 taacttctat acccagaaag cagacaccat acgtatgatg ctcccgttct ttcagcagtt
     1681 ccgggatatg gggatgaaag acaaagcagc cggagtatca gcagaaacgg cacagcaacg
     1741 tgcaaaagaa ttccactcag aaaaattttt tcactcactc cagagcacaa caacctttgc
     1801 tggcagaaaa tacacaaaca gcgatatgcc ttcgctgaaa aaaatgaaac taatggcaga
     1861 caccatttct gcggtttatc tcgatggata cgagggcaga cagtaaggga tttaccataa
     1921 tcccttaatt gtacgcaccg ctgaaatgcg ttcagcgcga tcacggctgc tgacaggtaa
     1981 aaatggcaac aaaccacccg aaaagctgcc gcgatcgcac ctgataaatt ttaaccgtat
     2041 gcatagctat tcagccatgt gaataacgct ggttttgcct gcgtaaacct catgacactg
     2101 tttttttcca tcttttcagt tgatgacata cgcagacatc gcgggatgag gctgaggaat
     2161 gagcgcgatc tggcaaagag gcaaaacaca gcaacaaaaa cgacactcca gaatcgcgcc
     2221 cggatgcgtt tttaacgcgt tccggtacca tctggcaacc tcccggaaca actcaccgtc
     2281 acatccccat tgacgggcca cgccataccc gtgcttcccg ttcctgctct tcatgccagg
     2341 accgcgcacg ctcccgttcc aggcgtgcct gcctttcctg ttcatccctt atctgctgtt
     2401 cgtgataaat aaccgactca agcggtccac ctgcccggct aatctctgca cctgctgact
     2461 caagtcgtcg cactgttccc tcagttgccc gttctcctgt cgtgtcagct cgaacatatg
     2521 ctgcaaatcc gtgaaggcgc tctcccagtc tttcagccgc tgcgtatagt cctgctgcaa
     2581 ttgctctaag gcgttcagta agtgcatttc cagctctgtc atactcactt actccctgac
     2641 cagtcttact gcgttcttct tctccaccgt ccagttgttt tcccccttca ccccggacgg
     2701 cagcaccaga aatttcccgt tcctgccctc gtgatacgtc acaccccatg ttttttcccg
     2761 gagtttcgcc agcgtctctt cctggtccct gatagccagg atgttcgccg caatccggct
     2821 ttcctgccac tgaatcagcc cccatgacgc cagaaaaatc ccgcccgtga cgcaaagcgc
     2881 cgtcagcgac gggtacagta tccgcccttt gatcagcttc cagagcagct cttcctgccg
     2941 ccgggccagt tcgttctctg tggcgctgaa ctgcgcgttc acggcactgt tcagcgtctc
     3001 cagttgttct ttcaccgctg ctgtgtgtgc gctgatagcg tctctgattt tctgcccgtt
     3061 taagttcagt tccctgtcta cagacgcttc gagcttcctg aactcgctgt tcagcatgtt
     3121 ctctgtagag acggcacgct ctttcagttt cttctcgaag tctgtcccca tttgtaaaag
     3181 attgctcata cagcgcccct ttcagcctga gattacgccc gccctccggg tcggcgatac
     3241 tgatactgct cctggttgtc ctcacaacct caaaacctgc cgctgtaagc gcctcagtga
     3301 catcctgacg cgtttttagc gctccggcat ggtaaagagc ctccagtccc ctcgtaatcg
     3361 cttctgcggc ctcctgtttc gctttcggca gattattcgg ggtgacaagt gtccgcctgt
     3421 tctccggtgc gttcgggtcg tgcagcccgt aatggtgatt caccagtgtc tgccaggcat
     3481 tgattcgcgg acggtccgcc cggtcgtaat agggctggag ccgttttccg ctcgccagct
     3541 ccatattcgg gatgacaaaa ttcagctcaa gacgcccctt gtcctggtgc tccacccaca
     3601 ggatgctgta ctgatttttt tcaagaccgg gcatcagtac ccgctcaaag ctctccatca
     3661 ccctttcacg ctctcccggt ggcagggtct gctctgcaaa agacagaacc cccgaggtgt
     3721 attttttcgc aaacggcgtg gcatcgatga gttcccgtac ctcttcggga gcaccccgca
     3781 gaactctcac cccttcccgg ttacgctccc ggcccagcag gtaatcaacc ggaccactgc
     3841 caccgccttt tcccctggca tgaaacttaa ctatcatccc gttctccctg tttacggacc
     3901 tcatccctaa gctcactcag ttcacgtccg atggccatca gtgcagccac cacatgaacc
     3961 cggtcatgcc ccgaccactg tccgctgttt atcttccggg ctatctgatt caggttattg
     4021 ccgaccgaag cgaactggcg caacagcggc ggtgccagtg tcggaagacc tgacgttttc
     4081 gatggcggtg cccccaggca gaccttacgc atccatgacg caagttgttt tccctcacaa
     4141 cgtgccagca gccgcgcatg ttcctcatcc gtgacccgta tcgtgagcat cctttcgcgt
     4201 ttcaccggta tcattaaaaa cctccgacag actccccaca catggagaaa cagaactgtg
     4261 actaaacagg aaaaaaccgc ccttaacatg gcccgcttca tcagaagcca gacgctgacc
     4321 ctgctggaaa aactgaatga actggacgtc gacgaccagg ctgacatctg cgaagcgctt
     4381 cacgaccacg ctgacgagct ttaccgcagc tgcctcgcac acttcgggga tgacggtgaa
     4441 aacctctgac acatgcagct cccggagacg gtcacagctg gcctgtgagc ggatgccggg
     4501 agcagacaag cccgtcaggg cgcgtcagcg ggtgttagcg ggtgtcgggg cgcagccatg
     4561 acccagtcac gtagcgatag cggagtgtat actggcttaa tcatgtggca tcagtgagga
     4621 ttgtatgaaa agtgcaccat gccgggtgtg aaatgccgca cagatgcgta aggagaaaat
     4681 gctcgtccgg gcacttttcc gcttcctcgc tcactgactc gctgcgctcg gtcgttcgac
     4741 tgcggcgagc ggagtctgct tgctcaaaaa cggcgatacg gttatccaca gaatcagggg
     4801 ataaggcaga aaagaacatg tgagcaaaaa ggcaaagggc aaaaaaagcc gcgtcgctgg
     4861 cgtttttcca taggctccgc ccccctgacg agcatcacaa aaatcgacgc tcaagtcaga
     4921 ggtggcgaaa cccgacagga ctataaagat accaggcgtt tccccctgga agctccctcg
     4981 tgcgctctcc tgttccgacc ctgccgctta ccggatacct gtccgccttt ctcccttcgg
     5041 gaagcgtggc gctttctcat agctcacgct gttggtatct cagttcggtg taggtcgttc
     5101 gctccaagct gggctgtgtg cacgaacccc ccgttcagcc cgaccgctgc gccttatccg
     5161 gtaactatcg tctcgagtcc accccggtaa gacacgacaa agcgccactg gcagcagcca
     5221 ttggtaactg aaaagtggat ttagatacgc agaactcttg aagttgaagc cttatagcgg
     5281 ctacactgaa aggacagcat ttggtatctg tgctccactt aagccagcta cccggttaag
     5341 cagtccccaa ctgacttaac cttcgactaa accgcctccc caggcggttt tttcgtttac
     5401 agggcaagag actacgacga tctgtaaagg atctcaagaa gatcctttac aggctaccac
     5461 taccaccact tcccatactc actccggtaa cagtggaaga tggtgaaaca gccccacctc
     5521 cagtatctct gacattgttg acttggcatg ctgcaagcag cattattcct agtgaaatgg
     5581 cacaaataat aatttttttc atatatacct ttattataat cctataggtc aatgatgatt
     5641 gatgaacatt caatagatat agacaataga aaagccaata acttattgta tttatttatg
     5701 gtaatcggag ttataccttt actctgtata ctagccgttt actatacaaa tccagacaat
     5761 ctgttcttgc acacaatagc taccagtact gaaaacatcc catcaataac ctccgcctac
     5821 aacccattaa tgacaaaggt tatggatatt tattgtaaaa cagcgccttc ccttgctttg
     5881 atattattta tcctgacatt taaaacgaga aagctaataa aaaaaacaaa ccgaaatgct
     5941 gtacttagaa gttgcttatt aagtccattt gtctgtgctg tttttttgta tttactctgt
     6001 ttccgaaacc ttgagctaac gacagcagga aggccagcca ggctaatgac caacaatgat
     6061 gcaacactat tgctatttta tattggcctg tacttaatca tttttttcat aagctatttc
     6121 acgctattca caccagttac cacgtttaaa ttattaaaag aaaggcagta accctgcctt
     6181 ccttttaccc ggtatttatt aatgcgcggg tttaatgatt tctttattta gtgcatctgc
     6241 aaacttgtca tcaattaatg cacctacaac tgctgcgagt agaataccta cgataccgac
     6301 agcaatagca ggagccccaa gagataaggc atatgcccct aatgtggctg aaaaaacacc
     6361 cagggccaca gcagaagcga tgccactgag cacccaggac tccacctcca gcatcagagg
     6421 tccccagttc ccggtttcat agccctcgat gcttttctcc cggaccttct caaccttcat
     6481 caccacatcg gcaaatttga aagccttgct gatattaccc agtttatttg ccatatcctg
     6541 agcatcaata cttcgccaga cgttcgccag tgcatcactg tcggccctgt taaatttaaa
     6601 ccccggatta gacaaaactt tatttaatga cgccattgca tcatcgtagc tacggatagt
     6661 tttcccctgg aaatttttga catcatcagc aatttctctt gctaacgact tataatcatc
     6721 tccaagataa tcaccgacct tattacctat atcagagata acttcagcgg ctttattaag
     6781 tacatcactc tgaatccggt cacggttcat actgaaagaa taaaacacat cataagcagc
     6841 ttttttagct tgatcctgtc gttgaggctc ttcattatta aatcctaatg cctcatatat
     6901 ctcttccggg gtcttatggt cgactttatc cataatacca gccttagctt tttcactccc
     6961 tacataagga cgaacagctg ttctagttac agataaaaca ttaccataat catcaagcac
     7021 cactaaatag tggaactgtt caacatcaac atcaaatttt ctcacattag gaggcaaacg
     7081 atcccacgca tcttcagcct gttgttttgc tttttcctgc cgctgagatt catct
//
