LOCUS       CP053635               25430 bp    DNA     circular BCT 09-JUN-2020
DEFINITION  Staphylococcus aureus strain 14638 plasmid unnamed, complete
            sequence.
ACCESSION   CP053635
VERSION     CP053635.1
DBLINK      BioProject: PRJNA612497
            BioSample: SAMN14375130
KEYWORDS    .
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 25430)
  AUTHORS   Tickler,I.A., Goering,R.V., Dewell,S., Le,V.M., Johar,L.,
            Obradovich,A.E. and Tenover,F.C.
  TITLE     Mobile genetic elements responsible for discordant Staphylococcus
            aureus phenotypes and genotypes in the same blood culture bottle
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 25430)
  AUTHORS   Tickler,I.A., Goering,R.V., Dewell,S., Le,V.M., Johar,L.,
            Obradovich,A.E. and Tenover,F.C.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2020) Healthcare Associated Infections, Cepheid,
            904 Caribbean Drive, Sunnyvale, CA 94089, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.6
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 1.00X
            Sequencing Technology :: Illumina Miseq/Oxford Nanopore MiniION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/20/2020 14:00:22
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 4.11
            Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region
            Genes (total)                     :: 2,742
            CDSs (total)                      :: 2,663
            Genes (coding)                    :: 2,595
            CDSs (with protein)               :: 2,595
            Genes (RNA)                       :: 79
            rRNAs                             :: 6, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 41 of 68
            Pseudo Genes (incomplete)         :: 23 of 68
            Pseudo Genes (internal stop)      :: 21 of 68
            Pseudo Genes (multiple problems)  :: 17 of 68
            ##Genome-Annotation-Data-END##
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..25430
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="14638"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="unnamed"
                     /geo_loc_name="USA"
                     /collection_date="2016"
                     /note="isolate 2 from Case 2"
     gene            complement(join(24703..25430,1..10))
                     /locus_tag="HA038_13560"
     CDS             complement(join(24703..25430,1..10))
                     /locus_tag="HA038_13560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000369394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="QKL36671.1"
                     /translation="MDNLLRTEFIKLKRSYMFLISILGTCVAPFMVVVASFISMRTKVP
                     TPNIVFKQLFEEVSLYHMLIIGPPLYGVIIAYLFGREYIEDTLKNLLIIPISRESFLVS
                     KIILLFLWIQTLSVIAWLLTLMLGMLLHFQGLSQSLIIDSFFTFVIGGVLLWILSPPII
                     ILSIYFKNYVPTIVLTIIITLINLMTANSEHRGLFPWAAVGDISRGTLPNTYPFLLSLI
                     IIIVTSIFSVIILFSYFKKTDIS"
                     /name="ABC transporter permease"
     gene            complement(3..932)
                     /locus_tag="HA038_13565"
     CDS             complement(3..932)
                     /locus_tag="HA038_13565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000074567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="QKL36672.1"
                     /translation="MKNLNNIIEINNLTKQYGSQIAVNNLSITVESGQIYGFLGRNGAG
                     KTTTIRMLLGLIKPTKGNIKIFEKEFESNKTEILKNIGAMVETPGFYSNLTAKENLTIN
                     AKILGIQKENAIEEVLEIVGLASEKVKLFKNYSLGMKQRLGIARALLHNPELLILDEPT
                     NGLDPIGIKEIRKLIKDLAQSRNITILISSHILSEIEQLVDKVGIIHNGVLLEEIMYED
                     LKKKNRQFISISVSDEEKVACLLETNFGIYDYKIKENGEFKIYSHIDRQQEINRLLVLN
                     NIDVFQMRVIEDNLETYFEDLVGGGTIG"
                     /name="ABC transporter ATP-binding protein"
     gene            complement(1048..1929)
                     /locus_tag="HA038_13570"
                     /pseudo=""
     CDS             complement(1048..1929)
                     /locus_tag="HA038_13570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501406.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /name="sensor histidine kinase"
     gene            complement(1926..2303)
                     /locus_tag="HA038_13575"
                     /pseudo=""
     CDS             complement(1926..2303)
                     /locus_tag="HA038_13575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866106.1"
                     /note="incomplete; partial on complete genome; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /name="response regulator transcription factor"
     gene            complement(2361..3035)
                     /locus_tag="HA038_13580"
     CDS             complement(2361..3035)
                     /locus_tag="HA038_13580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="QKL36648.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            3509..4975
                     /gene="msr(A)"
                     /locus_tag="HA038_13585"
     ARG             3510..4972
                     /name="msr(A)"
                     /gene="msr(A)"
                     /gene_name="ABC-F type ribosomal protection protein Msr(A)"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            5074..5973
                     /gene="mph(C)"
                     /locus_tag="HA038_13590"
     ARG             5075..5970
                     /name="mph(C)"
                     /gene="mph(C)"
                     /gene_name="Mph(C) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(6442..7185)
                     /locus_tag="HA038_13595"
     CDS             complement(6442..7185)
                     /locus_tag="HA038_13595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002508633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="QKL36651.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     gene            7611..8594
                     /locus_tag="HA038_13600"
     CDS             7611..8594
                     /locus_tag="HA038_13600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="QKL36652.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNK
                     PNILYLMKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSKIERPEVRK
                     SNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNQFTHNFDDKEMLLQEFPE
                     QLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHD
                     RGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication initiator protein A"
     gene            8587..8903
                     /locus_tag="HA038_13605"
                     /pseudo=""
     CDS             8587..8903
                     /locus_tag="HA038_13605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002483623.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            9450..9599
                     /locus_tag="HA038_13610"
     CDS             9450..9599
                     /locus_tag="HA038_13610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QKL36653.1"
                     /translation="MKIKTFATFTHRQLDKQVNRFLKNDIHVLEIQTHSNWLYISAIVF
                     YEDK"
                     /name="hypothetical protein"
     gene            complement(9767..10459)
                     /locus_tag="HA038_13615"
     CDS             complement(9767..10459)
                     /locus_tag="HA038_13615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QKL36654.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVE
                     YKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTA
                     FAAGCSVG"
                     /name="hypothetical protein"
     gene            10569..10763
                     /locus_tag="HA038_13620"
     CDS             10569..10763
                     /locus_tag="HA038_13620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QKL36655.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     gene            11879..12496
                     /gene="cadD"
                     /locus_tag="HA038_13625"
     ARG             11880..12493
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            12515..12862
                     /locus_tag="HA038_13630"
     CDS             12515..12862
                     /locus_tag="HA038_13630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="QKL36657.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="helix-turn-helix transcriptional regulator"
     gene            13019..13111
                     /locus_tag="HA038_13635"
     CDS             13019..13111
                     /locus_tag="HA038_13635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="QKL36658.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(13283..14254)
                     /locus_tag="HA038_13640"
     CDS             complement(13283..14254)
                     /locus_tag="HA038_13640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="QKL36659.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFEEFYKTIDQLLKGQHLGRTILKV"
                     /name="oxidoreductase"
     gene            14378..14797
                     /locus_tag="HA038_13645"
     CDS             14378..14797
                     /locus_tag="HA038_13645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="QKL36660.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            complement(15311..16156)
                     /gene="blaZ"
                     /locus_tag="HA038_13650"
     ARG             complement(15315..16156)
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.29"
                     /coverage="100.0"
     gene            16263..18020
                     /gene="blaR1"
                     /locus_tag="HA038_13655"
     ARG             16264..18017
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="98.8"
                     /coverage="100.0"
     gene            18010..18390
                     /gene="blaI"
                     /locus_tag="HA038_13660"
     ARG             18011..18387
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.21"
                     /coverage="100.0"
     gene            18654..19232
                     /locus_tag="HA038_13665"
     CDS             18654..19232
                     /locus_tag="HA038_13665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="QKL36664.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEAKENKNK"
                     /name="recombinase family protein"
     gene            complement(19455..19640)
                     /locus_tag="HA038_13670"
     CDS             complement(19455..19640)
                     /locus_tag="HA038_13670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QKL36665.1"
                     /translation="MNKLEKWSLVFIIFTFLSSLALLYFKYNFSSVMPVLSLSILTILI
                     LLTSIITVVSVNDEDT"
                     /name="hypothetical protein"
     gene            19902..20576
                     /locus_tag="HA038_13675"
     CDS             19902..20576
                     /locus_tag="HA038_13675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="QKL36666.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(20745..21316)
                     /locus_tag="HA038_13680"
                     /pseudo=""
     CDS             complement(20745..21316)
                     /locus_tag="HA038_13680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /name="HTH domain-containing protein"
     gene            21296..21484
                     /locus_tag="HA038_13685"
                     /pseudo=""
     CDS             21296..21484
                     /locus_tag="HA038_13685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913594.1"
                     /note="incomplete; partial on complete genome; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            complement(21592..22386)
                     /gene="aph(3')-IIIa"
                     /locus_tag="HA038_13690"
     ARG             complement(21596..22386)
                     /name="aph(3')-IIIa"
                     /gene="aph(3')-IIIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(22479..23009)
                     /gene="sat4"
                     /locus_tag="HA038_13695"
     ARG             complement(22483..23009)
                     /name="sat4"
                     /gene="sat4"
                     /gene_name="streptothricin N-acetyltransferase Sat4"
                     /tool="amrfinderplus"
                     /drug_class="STREPTOTHRICIN"
                     /identity="97.78"
                     /coverage="100.0"
     gene            complement(23006..23641)
                     /locus_tag="HA038_13700"
                     /pseudo=""
     CDS             complement(23006..23641)
                     /locus_tag="HA038_13700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="internal stop; incomplete; partial on complete
                     genome; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /name="aminoglycoside 6-adenylyltransferase"
     gene            complement(23782..24456)
                     /locus_tag="HA038_13705"
     CDS             complement(23782..24456)
                     /locus_tag="HA038_13705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="QKL36669.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            complement(24486..24689)
                     /locus_tag="HA038_13710"
     CDS             complement(24486..24689)
                     /locus_tag="HA038_13710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008406263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QKL36670.1"
                     /translation="MGFIEQIKAFILGVVEGLTEFAPVSSTGHMIIVDDMWLNTADDLG
                     SASATTFKVVIQLGGSVAKLNL"
                     /name="hypothetical protein"
     ARG             3510..4975
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="98.36"
                     /coverage="100.0"
     ARG             5075..5973
                     /name="mphC"
                     /gene="mphC"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="98.66"
                     /coverage="100.0"
     ARG             complement(22480..22997)
                     /name="SAT-4"
                     /gene="SAT-4"
                     /gene_name="streptothricin acetyltransferase (SAT)"
                     /tool="rgi"
                     /drug_class="nucleoside antibiotic"
                     /identity="97.16"
                     /coverage="95.56"
     ARG             complement(15312..16156)
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="95.37"
                     /coverage="100.0"
     ARG             complement(23304..23605)
                     /name="aad(6)"
                     /gene="aad(6)"
                     /gene_name="ANT(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="99.0"
                     /coverage="36.23"
     Typing          8960..9107
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          complement(6443..7185)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          7612..8594
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.593"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          8726..8895
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.605"
                     /coverage="91.0"
                     /evalue="1.04e-65"
ORIGIN
        1 gattatccaa ttgtgccacc tcctactaag tcttcgaaat aagtttctag attatcttct
       61 atcactctca tctggaaaac atcaatattg tttaatacta ataatctatt aatttcttgt
      121 tgtctatcaa tatgtgaata aattttaaat tcgccatttt ctttaatttt atagtcataa
      181 attccgaagt tagtttccaa caaacatgca actttttctt catctgatac tgatatactt
      241 ataaattgtc tgttcttttt ttttaaatct tcatacataa tttcttctaa caaaactccg
      301 ttatgaataa tacccacctt gtctactaac tgctctattt ctgacaatat atgacttgaa
      361 attaaaatgg ttatatttct agattgagcc agatccttaa tcaactttct aatttctttt
      421 atgccaatag gatctaatcc attcgtcggc tcatcaagta tcaataattc gggattgtgc
      481 aataaagctc tcgcaatccc taaacgttgc ttcataccta aagaataatt tttaaacaat
      541 tttacttttt cagaagctag tcctactatt tctaacactt cttcaattgc attttctttt
      601 tgtataccta atattttagc atttatagtt aagttctctt tagctgtcaa attactataa
      661 aaacctggcg tttcaaccat agcaccaata ttttttaaaa tttcagtttt attactttcg
      721 aactcttttt caaatatttt aatattacct ttcgtaggtt taattaagcc taaaagcatt
      781 cttatagtag ttgttttgcc tgcaccattt cttcctaaaa aaccataaat ttgtccactt
      841 tcaacagtta tactcaaatt attaactgct atctgacttc catattgctt tgttaagtta
      901 tttatttcaa ttatattatt caaatttttc acctctggca cctttcttag tttgttgtta
      961 cctttatctt acgcgcgatt agaaaaggct gcctttatct attcttacaa aaacagccgc
     1021 taatcttaca aaaatgaaag attggagtta tttaaattga atggtgaata ttgaaccatc
     1081 gtttaatgta gatgtagcac ttactttatg gcctaagcgc tttgagattg tgctgacaat
     1141 atataaacca ataccgcttg atttctcact tattctaccg ttatagcccg agaaaccttt
     1201 atcaaagatt ttcggtaaat cactcgcatt aatgccgata ccgttatctc ggattgataa
     1261 tttctttgta ttttcgtcaa acgtaatcca cacatctttg ccacgtgcat attttaatgc
     1321 attgtttaat atttgctcaa tcataattga tgcccatttg gcatctgtta atataaccgc
     1381 ttcacttttc tcataatgca actttgtttg atgatgaata aactgtatcg cataacgttt
     1441 aatcagtggt cgaattaatt catctacact cacttccata aagaccatgt atgtcttttg
     1501 gttcatgagt ttcaaatagt tcagtgcaag attcgtgtaa ttatcaattt gtaagacttc
     1561 attacgcacg ttagaaatca cgtgttcatc aggatcttca agcagtaact ttgatgctgt
     1621 aatcggtgtc ttgatttgat gcacccacat taaaaaatat gactctaact cactttggta
     1681 gttaataaag tcattacgaa gtttatggtt ttcgattctt aaatcttcgt tctgttcctg
     1741 tagtgtttat tcttttttaa agttcatgta atggataccc cagtaaatca ttgaaacaaa
     1801 caatacaata cctagaccaa tcatatatgc ttgcatcggc acattataca tgaataatat
     1861 aaagtagaat aaagcacaag taaggatgac aatataaatt tcacgttgga ttgatttcaa
     1921 gaaattcata cgtcacctac acgatatccg acatttttct tcgtttcgat aaaatctgta
     1981 agtcctagtt tttgtagctt tttgcgtaaa cgtgtaatgt tgacagcaag cgtattgtca
     2041 tcaatgaagt gttctgattc ccagcatttt tcgattaacg cattacgact gacgaatttg
     2101 cccttgttct ggaataagct atgcatgatt tgcaattcag tgtgtgtcag gtctatggtt
     2161 tcttcattaa atttaagctt tgctgcatca agtagtaact cgcaatcatc tactgttaaa
     2221 ttattaactt gagtggtgaa atcatacgtg cggcgtaata gtgcttgaat cttagtaatt
     2281 gtaacagtca tattaaatgg ctggttctgt tgcaaagtaa aaaatatagc taatcactaa
     2341 tatatcatgt cagtgttcgt ttaacttgct agcatgatgc taatttcgtg gcatggggaa
     2401 aatccgtaga tctgaagaga cctacggttc tttttatata gagcgtaaat acattcaata
     2461 ccttttaaag tattctttgc cgtattgata ctttgatatc ttgtctttct tactttaata
     2521 tgacggtgat cttgctcaat gaggttattc agatatttcg atgtacaatg acagtcaggt
     2581 ttaagtttaa aagctttaat tattttagcc attgctgcct tcgttgaagg tgcctgatct
     2641 gtaactacct tttgaggctt accaaattgt ttaatgagac gtttgataaa cgcatatgct
     2701 gaatgattat ctcgttgctt acgcaaccaa atatctaatg tatgtccctc tgtatcaatg
     2761 gcacgatata aatagctcca ttttcctttt attttgatat acgtctcatc aatacgccat
     2821 ttgtaataag cttttttatg ctttttcttc caaatttgat ataaaattgg ggcatattct
     2881 tgaacccaac ggtagatcgt tgaatgatga acgtttacac cacgttctct taatatttca
     2941 gatatatcac gatagctcaa tgcatatctt agatagtagc caacggctac agtgataaca
     3001 tccttgttaa attgtttata tctgaaatag ttcatacaga agactccttt ttgttaaaat
     3061 tatattataa attcaacttt gcaacagaac cgtattttat gagtacactc taaattaagg
     3121 agatgtataa tcaatctaaa attgtatttt tatacttttg ttatataatc tttctcctta
     3181 gagatatatt gtaaaaaaac caacaaaatg ttatattaac attactattt tatcgatgaa
     3241 ggaggattaa aatgacagct tctatgagac tcaaataaac ctttttgaat acaaaactaa
     3301 attaattcaa aaaggcttgt ccgcaataca cactcatagg atgacttatg tcatttttta
     3361 tccttcgata ggaataataa acgctttcaa atactaaaac atcataataa atttttaagt
     3421 gtttgaaagt gtaatgtgaa tgagacggga gtagcctgtc tcattttttt gcgtacacgt
     3481 cctttaaata tacaaggagt gtataaatat ggaacaatat acaattaaat ttaaccaaat
     3541 caatcataaa ttgacagatt tacgatcact taacatcggt catctttacg cttaccaatt
     3601 tgaaaaaata gcacttattg ggggtaatgg tactggcaaa accacattac taaatatgat
     3661 tgctcaaaaa acaaaaccag aatctggaac agttgaaacg gttggcgaaa ttcaatattt
     3721 tgaacagctt aacatggatg tggaaaatga ttttaacacg ttagacggta gtttaatgag
     3781 tgaactccat atacctatgc atacaaccga cagtatgagt ggtggtgaaa aagcaaaata
     3841 taaattagct aatgtcatat caaattatag tccgatatta cttttagatg aacctacaaa
     3901 tcacttggat aaaattggta aagattatct gaaaaatatt ttaaaatatt actatggtac
     3961 tttaattata gtaagtcatg atagagcact tatagaccaa attgctgaca caatttggga
     4021 tatacaagaa gatggcacaa taagagtgtt taaaggtaat tacacacagt atcaaaatca
     4081 atatgaacaa gaacagttag aacaacaacg tcaatatgaa cagtatataa gtgaaaaaca
     4141 aagattgtcc caagccagta aagctaaacg aaatcaagcg caacaaatgg cacaagcatc
     4201 atcaaaacaa aaaaacaaaa gtatagcacc agatcgttta agtgcatcaa aacaaaaagg
     4261 cacggttgag aaggctgctc aaaaacaagc taagcatatt gaaaaaagaa tggaacattt
     4321 ggaagaagtt gaaaaaccac aaagttatca tgaattcaat ttcccacaaa ataaaattta
     4381 tgatatccat aataattatc caatcattgc acaaaatcta acattggtta aaggaagtca
     4441 aaaactgcta acacaagtac gattccaaat accatatggc aaaaatatag cgctcgtagg
     4501 tgcaaatggt gtaggtaaga caactttact tgaagctatt taccaccaaa tagagggaat
     4561 tgattgttct cctaaagtgc aaatggcata ctatcgtcaa cttgcttatg aagacatgcg
     4621 tgacgtttca ttattgcaat atttaatgga tgaaacggat tcatcagaat cattcagtag
     4681 agctatttta aataacttgg gtttaaatga agcacttgat cgttcttgta atgttttgag
     4741 tggtggggaa agaacgaaat tatcgttagc agtattattt tcaacgaaag cgaatatgtt
     4801 aattttggat gaaccaacta attttttaga tattaaaaca ttagaagcat tagaaatgtt
     4861 tatgaataaa tatcctggaa tcattttgtt tacatcacat gatacaaggt ttgttaaaca
     4921 tgtatcagat aaaaaatggg aattaacagg acaatctctt catgatataa cttaaaaact
     4981 atacactaat ttatattgaa tattaggttc atttatatca atataaaaaa tacgttcaca
     5041 agaaaaatat aatagaaata aggatccaat aaaatgactc gacataatga aattattaaa
     5101 tgtgcagaaa aatatcaatt acacatccaa cctcaaacaa tctcattgaa tgaatcggga
     5161 cttgattttc aagttgcatt tggaaaagat aaacatggag tagaatgggt tttgagacta
     5221 ccaagaagac ctgacgttta taaacgaaca aaacccgaaa aacaaacggt agacttctta
     5281 cagaagaatg tttcatttga aataccgaag tggaaagtac atgcaaaaga ccttattgct
     5341 tacccaaaac ttacaggtaa acccgcagcc acaatagatc cagaaataca aaattatgta
     5401 tgggaaattg aacacaaacc attaccagaa aactttatta acacattagc tgaaacactc
     5461 gtagatttac acaacatacc agaagaaaac attaacgttc agcatataaa tatcaaaacc
     5521 atacaagaaa taaaaaatga ctttcaaaga agaatgaata aagttaaaga aacttatggc
     5581 gtatcagatg aattatggaa cagatggaaa caatggttag aaaacgacga actatggcct
     5641 cgacatgcga ccatgataca tggggactta catccaggac atataatggt agataaccaa
     5701 gcaaacgtca caggtctcat agactggact gaagcaaccc actccgaccc atcaatggac
     5761 tttataggac accatcgtgt attcgacgac gaaggattag agcaacttat aacagcatac
     5821 ggtaaagctg gaggtgaaat atggccacga atgaaagagc atataataga actcaatgca
     5881 gtattcccaa tgtttatcgc tgagtttgct atggaatcag gagaatcggc gtatgaaacg
     5941 atggcattga aagagttagg tatgaaagag tagaacttat attaaaagag gcccatttta
     6001 aagacgaagg caatcctgat gaaattttaa aactgcgttt aattagtgat ggtctttggt
     6061 tttctataat gtattaaata tctggacatg gaacaaatgc aacaaatgga aagaatcgtt
     6121 ttcgaaattt ctaactcctt aaatcaggag gataaataaa cggtcatttt cattgaaagc
     6181 acttatataa atttcatcaa ttttaatacc taccgtaaat acatttcata agtattaaac
     6241 agatgattaa aatttttagt taatttaaat atttatgata gagatgacct tcaaatgaac
     6301 gtttataacg caatcatgat gagagtatta atacagttaa ttatttgaaa tactttagtt
     6361 tacataatcg atgattacca gaagttctca ctatataaaa gacactaaaa ttttataact
     6421 tttagtgcct aatcaattat tttagctacc aaacaaacga ctccaaaacc cctttttagg
     6481 ttccgtttct tcactctttt cttctatatc actatcattg tcatttagat tagctggaac
     6541 gtcttctttt tttgcttctt caccttgtgt actttcgtcg ctttgacttc cagatatatc
     6601 cttatattga atctctgttt ctttagtttc ttcctgatct ctgttaatat ttacaggatt
     6661 agtagtatat gttttttctt gtgcatcaac gttttgtcta gtgttagtag atgtatcaaa
     6721 gggataatta aggtgttttt ctttttctaa ttgattttct aatttttgaa tctttttatt
     6781 actctctaat gccagaactt gctgattttc aagcaatttt gatctttctt gcaactcttt
     6841 tctgtaaaat tcaattgttg tttcatgacg actttcttgt ttttcaattt gattatttaa
     6901 agtatcaatc tgatttttaa ggatttctac tatttgagca tcgcttttcg attcaaaatt
     6961 aatattatcc gacccttttt tttgtttgtc ttcagtagta ctttcaaaac catatttctt
     7021 tttattttca tttactcttt gaatgatttt ttctatatcg gtatcttctt taataaacga
     7081 agtgttttcc tgttttattg tctctatatt caatcgctta atattattaa aaatcgtttg
     7141 cttactaacc cctaattctt cactcaactt tttcacactt ttcatatcat caacccttta
     7201 taaaatgttt ataaaccctt gataaaatat tataagctta taatgcttaa taataaagtg
     7261 attaataaat aaaaataaac atccatcaac ctttttatca agggtttatg aaaggtttat
     7321 gatatttatc aagggtttat aaacccttga taaagctata ttttcccttt tataagttta
     7381 tttaaagtgc tataataaac ttaatataac aaaaacccca actactggta atagtcgggg
     7441 tttggtaata aaacgtttag aaactgttta tttatataat tttcgatact tgtattatat
     7501 aatgaataat atcttagtgc aagcacctaa atcattaaat aaatgtaaag ctaaataaaa
     7561 acgttttatt acctcttacc aaactaaaat atggaaagag gttttttgtc atgcaaaatc
     7621 aatattttac agtgcaagaa aattacaaag aaagatttta tcaaatccct aaagtattct
     7681 ttaccagtga aaattataaa aatctaacta atgatatgaa aatagcctat gctatcttac
     7741 gtgatcgctt aaatttatct attaaaaata gctgggttga tgaagatggt aacatttact
     7801 ttgtttattc aaatgaaaag ctaatggaaa tcttaaattg taaaaaagaa aagttaacaa
     7861 aaataaaaaa agggttagaa aacgatggtc tactcattca aaaacgacgt ggtttaaata
     7921 aaccaaatat tctatattta atgaaaccta ttgtcacaga acgtgatatt tacaaaatag
     7981 aaaaagaaga aaacgatgtt gaaccttacg gcgagaagga agttcgaaaa tcgaacgtcc
     8041 agaagttcga aaatcgaacg tccagaagtt cgaaaatcga acgtccagaa gttcgaaaat
     8101 cgaacactaa tgatactgac tttaatgaca ttgactttaa tgatactgag aataatgata
     8161 tgaatgactt gaatgatata aagtacaaaa atgaaattag taatcattca aatcattcaa
     8221 atcaatttac acataatttt gatgataaag aaatgctatt gcaagaattc ccagaacaac
     8281 taactaatta tttattaaaa tatgattata gagatttaga aatcataaag gctgttattc
     8341 ttaaagcaaa aaaatcattt aattcaaggc atgaagatat gcattacatg ttagaggaca
     8401 ttgaggatga aatattaact tctttaaaaa gacttaaaaa agctatacat gataggggag
     8461 ttaaaggcca aaaggaaaca atcaagtcaa tgcaagctta tttaatgcaa acaattctaa
     8521 ctgaacttga agaaacacat gccctttata tgcgccgtaa aaacatgaaa caatataata
     8581 tctttaatca ataattcaaa tgattttata acactcgaag agacatcaaa atattccgtt
     8641 aaatcatctg actttttaac tgatgacgac gaaaaaaatc aagaaattgt aagtgattta
     8701 gaaaaaggtt tgtatcgaaa acgtatgtta agttatggtg gattgcttaa acaaaagcat
     8761 aaaattttaa acttagacga tgccgaagat ggtaatttga ttaatacaag tgatgaagat
     8821 aaaacgacag acgaagaaaa aaagcacatt caattaccgc aatttggaat ttcgaaaagc
     8881 aaaattatta tttaagacat tagtgataac tgatgtcttt ttttattgtt tttctgtaaa
     8941 aaagtgctgt cttatttttg tgacaaatgc tgtatgtagt gtcacaaaag tgtgacacta
     9001 cagctttgta tgatatcact ttaaaataac ttaaaaccct tggaatgtct ggccttgcca
     9061 gatctatcat ttttgaatga tagcaaattt cccttatgct cttacggaga ttttagagtt
     9121 aaattaaaat ttctaagttt ttgataagaa aagccctgca ggaatttaga aaaacatggg
     9181 gaagttttaa agtattttat gctaattttt aaatttgcat gtaaatgggc agtatctaaa
     9241 aaattagtca ctgattttgc tgaaattttt gtttgtgaaa ttagcatata tttatttggc
     9301 tcatatttgc gttttaagag actgtataga tttttaagta caaaacctat atgatttgcc
     9361 tctaagtctt caaaatgcct cttaaaatcc aaaataaaag tgtttaatat tgtaataagg
     9421 attgctattt ttataaaagg agagatatca tgaagattaa aactttcgct acttttactc
     9481 atcgtcaatt agataaacaa gttaataggt ttttaaagaa tgatattcat gtattagaaa
     9541 ttcaaacaca cagtaattgg ttatatattt cagctattgt tttttatgag gataaataag
     9601 gaacatcgta tttatgccga aaaaatttat tgatgttgag aagaaccctt aactaaactt
     9661 gcagacgaat gtcggcatag cgtgagctat taagccgacc attcgacaag ttttgggatt
     9721 gttaagggtt ccgaggctca acgtcaataa aacaattgga ataaaatcaa cctacagagc
     9781 atccagctgc aaatgcagtt ccgcaaactg cttcacatac accgccggct attggattta
     9841 cgattgccca tactccacag tagtgagcac atgcataaag tccagccata ctacaagcga
     9901 atgctttgcc gttccatttg aatcctgcat atgttaccgg tctgttttta tcaacttttt
     9961 cagccttata ttcaacgtaa tttttgttaa taagtatttt tccctctttg ttttcagtca
    10021 tacttctttt ttcggcaatg aattttgtga tttttttgtt gtagttatca tatattgttt
    10081 cagaaactac aatttctttt gttttttcat ttttataagc gttattagct atgtagccat
    10141 atgcattttt atcatttgct tctgtagcta gatattttaa tttagaattt ttgtcttcta
    10201 gctttatttt tttaaatcct tcttttttca tttgcttttc gaatttttgc atatcttcat
    10261 ttttattttg caattgttct agaaaactta tttctttctt ggtcatttgt gatacttcga
    10321 tgtttttgct tttcaatttt tctttttgat tttctagtaa agaacttttt tgttcttcat
    10381 ttgcgtaagc attagaaaaa ttcgcgctaa ataccagtag gaacaaggaa attattgaaa
    10441 ataattttat aattttcatt tgatacctcc aagataataa gatattttaa ttgtataagt
    10501 aagcgcttta taaaatcaat atttatttta atatatttat aaacatattt ttgaaaggag
    10561 tctattttat gaatgaaaat ttagaaaaat atataaaaag tttgccactt ttaggtttgt
    10621 taattagtat tttgttaatt gttttattct tttttatttt agatgttgat gaagatttat
    10681 tcgtggtttt tttatactgt ttattgcctt tgatagttaa tttgtctatt tatggttttt
    10741 atgtttttgt taaaagaaag taagattatg aataattttg tttttaattt gtatgctttg
    10801 agggggttgg aaaacggtag gtgtatagat tagatttctt gtttttttga aacgagtgtg
    10861 aacgagtttc ttcttgtctt gatttttgat aaaaacgccc tacaggaatt tagaaaaacg
    10921 tggggaagtt ttaaagaatt ttatgctaat ttttaatttg catgtaaatg ggcagtgtct
    10981 aaaaatagtt attgtttttg ctcaaatttt tgtttttgaa aatagcatat atttatttgg
    11041 ctcatatttg cgttttaaaa gcatatataa gttttagata taaaactata tgaatcaccc
    11101 ctaaatcttt aaaatgccct cttaaaattc aaaataaggg cataaaaaat aaaagctacc
    11161 ccagataaag tgaggtagct ttttctttca tacggtctat ttatttttct ttcgacgccg
    11221 tatcgtcgat gtaattcaaa aaagttatgg gctataaatc tacatcactt tttcaagaat
    11281 gtagtagcaa tattcaacgc aaattaattt ttataactgc tcggaatatc tcaagccgtt
    11341 tctttaattt tgaaataaaa aaatcgacga aggtcgatta cgtttttgca catgtcgatt
    11401 tatccgacgt ataagtgcgc ccttacggga tttaactaga ttataacgac gaattttaga
    11461 cctgtaaagc aataacaatt aggtctacca ggtagataaa gtgtacaaaa tagaaccgaa
    11521 aaagttattt attttgaaga tttttcgtag atataatttg ctaataaact tcctaaaact
    11581 gaataaagaa aaatagttaa actcatgtaa tcactccata attctgaagt gtctccatgt
    11641 ctacgcatag acacgcattt atgccgaaaa aatttattga tgttgagaag aacccttaac
    11701 taaacttgca gacgaatgtc ggcatagcgt gagctattaa gccgaccatt cgacaagttt
    11761 tgggattgtt aagggttccg aggctcaacg tcaataaagc aattggaata aagcacctat
    11821 gattatttaa aaatataagt tataatacat tcaaaaatat ttttgaatga ggtgtattat
    11881 gattcaaacg gttgttgctg ctgctgttct ttatattgct acagcagttg atttattagt
    11941 aattttatta atattttttg ctagagcaaa gactagaaaa gaatatagag atatttatgt
    12001 tggtcaatat ttagggtcta ttattttaat attagttagt ttgtttttag cttttgtatt
    12061 aaattatgtt ccagaaaagt ggatattagg tttattgggt ttaataccaa tttatcttgg
    12121 aattaaagtg gctatttatg atgattgtga aggagaaaag agagctaaaa aagaattgaa
    12181 tgaaaaagga ttgtctaaat tagttggtac ggttgcaatt gttacgatag caagttgtgg
    12241 cgccgataat attggtttat ttgttccgta ttttgtgaca ttaagtgtta ctaatttatt
    12301 acttactctg tttgtctttt taattttaat tttcttcttg gtgtttactg cacaaaaatt
    12361 agctaatatt ccaggaattg gagaaattgt tgagaaattt agtcgttgga ttatggctat
    12421 tatttatata gctttaggtt tatttattat tattgaaaat gacactattc aaacaatttt
    12481 aggatttata ttttaattta gggtgtgatt ttatatgagt tatgaaaata cttgtgatgt
    12541 gatctgtgta catgaggata aagttaacaa tgctttaagt tttttagaag atgataaatc
    12601 taagaaatta cttaacattt tagaaaaaat ttgtgatgag aagaaattga aaatcatatt
    12661 atctttgatt aaagaagatg agttgtgtgt ttgtgatatt tctttgatat tgaaaatgag
    12721 tgttgcttca acttcacatc atttaaggct tttatataaa aatgaggtac ttgattttta
    12781 taaagatgga aagatggcat attattttat taaagacgat gaaataagag agtttttctc
    12841 taaaaatcat gagggttttt gaaacgagtt tcttcttgtc ttgatactat aaaaaacaaa
    12901 gttatataac ataagacgac ttatcggaag tagatatgct tgtatattca cagatggtat
    12961 aataatagag tcgcctatct ctcaggcgtc aattgacgaa gagaggaggt gcattacttt
    13021 gctaatcatt ttcgttcaca tcatagcacc agtcatcagt ggctgtgctg ttgcgtatta
    13081 tacttattgg cttagtaaac gcaacaaata attaataggc gactttataa gccagcatcg
    13141 aaaaaatccc cacactactg caatagtgtg gggattggtg cattaattgt taatcatttt
    13201 cgttatataa attataacac tggttagtag agaaatgcaa aatgattgaa ttaatagtaa
    13261 atgtattaat gaatactcac acttatactt ttaaaatagt tcttcctaaa tgttgtcctt
    13321 ttaaaagctg atctatcgtt ttatagaatt cttcaaatcc aatttcattg tatagaagtg
    13381 aatttcctat attccattca tttgctaact tactccatat atcttcacgg atattatgat
    13441 caacatatac agaatcaatg ccaattaatt taatacctct aagaataaac ggtaatatat
    13501 tagcgttaag tgaatttcct gctacatttc cacatacagt agcaacacct tgataattta
    13561 gacgttttaa accgtataat gttacattac tccccactgt atctaagaaa taatcaaaaa
    13621 tacctttttt aagcggttta ttatcatctt caattattat tacttgtttt gcacctaatt
    13681 tttttgcgat ttctatttgc ttttcttttc ttacgatagc agtgatattt tcatatccaa
    13741 ttttatgtaa aatttgtata gcaacactgc ccacaccacc tgtagcccca gacactaaaa
    13801 tttcaggttg tgatttgata ttcattccat atttttctag ttcaaaaatt gataatgctg
    13861 ccgtaaaacc ggctgtgcca tataccatag actctttaat agacatttct tggggaatag
    13921 gaacaatcca ctctccaggc acttgtgcat attctgaaaa tccacctgta tgtgtcacgc
    13981 caacatcata accagtaact aatacattat cgccttcttt aaacttatca ttcgaacttg
    14041 attcaacaat acctgcaaaa tctataccag gaatcatagg ataatctcta attacaccgc
    14101 ctttatattg taaagctagc atatccttat aatttattga agagtatacc acttttacta
    14161 atacatcacc cttcgataaa tgagattcat caactttttc tactttataa ctaacatttg
    14221 atgcactttt tctcactact accgcattga acatttatta gccttctttc acaattgttt
    14281 tgtagaagta tgtttttgtt gcaaaactat tttcctacaa aacttatcat gatatgataa
    14341 gcgagtcaat actaatgatt taagagaggt tttagttgtg gaattagata attgtataaa
    14401 ttatttgttg agtacttctc agaatagagt ttttaaacat tttaaaagtt tattaagtcc
    14461 ctataatatt actccagcag aatatggtgt tttgaattgc ttgattaata gtaatttgaa
    14521 tacacctaaa gcgattggta atactttaaa tttagaacct tcaacaatat ctggaatatt
    14581 agataagatg tccaaaaagg atctaataac acgtcaaact gataatgaaa atagaagaac
    14641 tgtgctaata aacagtacaa ataaagcaaa agacttatgg ccaacattag aaaagaaagc
    14701 ctatcaactt aataatcatt acttcgctaa tttaactaat gaagaaactg tagtgtttaa
    14761 aaagatatta ctaaagataa ataaaactac gttttaattt ttacgttata aaaaagttga
    14821 agtgcgaatt ataatcgagt aaatataaat gatagcttag cttaattata tattaaagcc
    14881 aactatactt ttattcccga aaaacctact atccaaattt ctaagatact ttagcctcta
    14941 taataaacat attgtaatat aatttatgta ttatttaggt ttaccctaat cgaacaataa
    15001 aaaatacttg taaaatgcta ttgtcacttt gcttgatata tgagaattat ttaaccttat
    15061 aaatgagaaa aaagcaacgc actttaaata agatacgttg ctttttcgat tgatgaatac
    15121 ctataattaa actattcatc tattatttat gattttttgt atatacaata tttctagttt
    15181 gttaaagaga attaagaaaa taaatatcga aaataataga gggaaaatca gtttttgata
    15241 tcaaaattat acatgtcaac gataatacaa actataagat gatatcagta tttattatgc
    15301 atttagaata ttaaaattcc ttcattacac tcttggcggt ttcacttatc aacttatcat
    15361 ttggcttatc acttttattg tctttattcg taaaaatgac taaaacaata ggttcagatt
    15421 ggcccttagg ataaacaaaa gcaacatcat ttctagaagc atatgttatt gcttgaccac
    15481 ttttatcagc aaccttacag tcttttgaaa caccgtcttt aattaaagta tctccgcttt
    15541 tattatttaa cattaaatca agtaagaatt ttttgttttc tttgcttaat tttccatttg
    15601 cgataagttt atttaaagtc ttaccgaaag cagcaggtgt tgaagtatct tttttgctct
    15661 ttggtgaata ataatttaat tctatctcat atctaactgg atttgttact ttatctccta
    15721 gtccttttag acgttgttta acttttttga tcccaccgat ctcttttata attttattgt
    15781 ttgctgtatt atcactatat gccattgaag cctcaataag ttcttttaaa gtgatatctt
    15841 ttcctacata tttttctaaa ataggagaat aagcaactat atcatctttg ttaatatgta
    15901 tttttttatt taacttatta taaggtactt gttctaacaa aatagcacta tttatcgctt
    15961 ttgaagtcga agcataggca aatctcttat ctgaattaaa ttttacttcc ttaccacttt
    16021 tagtatctaa agcataaaca ccaatatgag cattatattt tttttctaaa tcatttaact
    16081 ctttggcatg tgaactgttt gaattacatg cacttaaaac taaagcaatt acaattaaaa
    16141 atattaactt tttcaaaata aaccctccga tattacagtt gtaattttta taaatcaata
    16201 atattacaat tgtaatattg atgtcaattg tttattataa atatttgaaa gaaggtgtca
    16261 aaatggctaa attactaata atgagcgtag taagcttttg ttttatattt ctattgttag
    16321 tattttttag gtacatatta aaacgctatt ttaattatag tttaaattat aaagtttggt
    16381 atctaactat gcttgctgga ttaattcctt ttatcccaat taaattctct tttataaaat
    16441 ttaataatgt gaataatcaa gcgcccacag ttgaaagtaa gtcacacgat ttgaaccata
    16501 acataaatac caccaaacct attcaagagt tcacaacaga tatccataag tttaattggg
    16561 attcaattga taatatctgc acagttattt ggatagtttt agttattatt ttaagtttta
    16621 aatttttgaa agccttatta tatcttaaat atttaaagaa acagtcactt tatctaaacg
    16681 aaaatgaaaa aaataaaata gatacgatac ttttcaacca tcaatataaa aaaaatattg
    16741 tgattcgaaa agcagaggct attcaatctc caataacttt ttggtatggg aaatatatta
    16801 ttttgattcc tagttcatat tttaaaagtg taattgataa aagactaaaa tatataatac
    16861 tgcatgaata tgctcatgct aaaaatagag atactttaca tttaattatc tttaatatct
    16921 tctctattgt tatgagttac aatccattaa tacatattgt aaaaagaaag ataattcatg
    16981 acaatgaagt agaagctgat agatttgttc ttaataatat taacaaaaat gaatttaaaa
    17041 cttatgcgga atctattatg gactccgtat taaatattcc attttttaat aaaaatatat
    17101 taagccattc atttaatggt aaaaagtcat tactcaaaag aagattaatt aatataaaag
    17161 aagccaattt gaaaaaacag tctaaattaa ttccaatttt tatttgtatt tttacttttt
    17221 tgctcatagt aattcaaagc cagtttttga tggggcaatc cataactgat tataattata
    17281 aaaagccctt acagaacgat caccaaattt tagatgaaag taaaaatttt ggttcaaata
    17341 gtggatcttt cgtcatgtac agcatgaaga aagacaaata ctatatttat aatgaaaaag
    17401 aaagtagaaa aagatattct cctgattcaa cttataaaat ttatttagcg atgtttggac
    17461 ttgaccgtca tatcataagt gataaaaatt cacgtatgtc atggaatcat aaacattatc
    17521 ctttcgagtc ttggaataag gaacaagatt taaatacagc aatgcaaaat tcagttaatt
    17581 ggtacttcga acgtattagt aatcaaatac caaagaacta tactgcggct caactcaagc
    17641 aattaaatta tggtaatgaa aatttgggaa gttataaaaa ctattggatg gaagatagtt
    17701 tgaaaatatc taatcttgaa caagtaatag tttttaaaaa tatgatggaa caaaataacc
    17761 attttagtaa aaaagcaaag aatcaattat cttcttcatt attgattaag aaaaatgaaa
    17821 agtatgaact gtatgggaaa acaggtacag gtatagtaaa cgggaagtat aataatgggt
    17881 ggtttgtagg ttacgtaatt acaaatcatg ataagtatta ttttgctaca catttatcag
    17941 atggaaaccc gtctgggaaa aatgctgaat taatcagtga aaaaatatta aaagaaatgg
    18001 gtgttttaaa tggccaataa gcaagttgaa atatctatgg ctgaatggga tgttatgaat
    18061 ataatatggg ataaaaaatc agtatcagct aatgaaattg tagttgaaat tcaaaaatat
    18121 aaagaagtta gcgataaaac aattagaaca ttaatcacaa gactatataa aaaagagatt
    18181 ataaaacgat acaaatcaga gaatatttat ttttactcat caaatattaa agaagacgat
    18241 attaaaatga aaactgctaa aacttttctt aataaactgt atggagggga catgaaaagt
    18301 ttagtgctaa attttgcgaa aaatgaagaa ttaaataaca aagaaattga agaattgcga
    18361 gacattttaa atgatattag taaaaagtaa ttagagatat gtttcaaaca ttatacatat
    18421 gtaaactata cttgactctt attaaattag ttttgttaat aacatttaaa atatattagt
    18481 aaagatgaga gtgtacataa aataaccatt ttctgtacac tctcttttta tgtctaaata
    18541 agtatgtatt acatagaatt atgtgttcaa aaacccaaca aaaaatctat gttcacaaaa
    18601 gacctcgtaa tcaagttatg gtacactaaa ggtgtatata ggaggtctgt attttgaaaa
    18661 taggttatgc aagagtttca actggattac aaaatttgaa tttacaggag gatcgattaa
    18721 atacatatgg ttgtgaaaag atatttaatg accatatgag tggttcaaaa agtaagcgac
    18781 ctggtttaga taaagcaatt gaatttgcga ggtcaggaga tacgattgtt gtttggagat
    18841 tagatagact aggacggaac atggaggatt taatcacgtt agttaatgaa cttaacgaac
    18901 gaggtgtgag ttttcatagt ttagaagaaa atataacgat ggataaatca agttctacag
    18961 gacaattatt atttcattta ttcgcagcat ttgcagagtt tgaacgtaat ttaattttag
    19021 agcgatcatc agccggtcga attgcagcac gtgctagagg ccgatatgga ggtagacctg
    19081 aaaaattaaa taaacaagat ttaaacttac ttaagacact ttatgataat ggtacgccaa
    19141 ttaaaacaat tgcagagcag tggcaagttt cacgtacaac tatttatcgt tatctcaata
    19201 aattagaggc aaaagagaat aaaaacaagt agagcaacta atctagctta ctataatgaa
    19261 tctactaaat aattttatat atcattaaca tacaaagact ttgattcaat gtcactcgat
    19321 gtaaaagaga cgttctgaca gcgtctaaaa tctcataata ttttcctgtt atgagatttt
    19381 aataataaca caagaaaaaa gcgtacaaat tcgtacgctt ttttaatata atacctgttt
    19441 cactaatgaa cgttttaagt atcttcatca ttaactgaaa ctacagtaat aatactcgtc
    19501 aacaatatta gtatagttaa aatagaaaga cttaggactg gcataaccga actaaaatta
    19561 tatttgaaat ataaaagtgc taatgaagag agaaatgtaa aaataataaa taccaaagac
    19621 catttttcta atttattcat tggcttcacc tctttgaact tttatataat cataggagat
    19681 atttttacta cgatttataa aaaataagaa gataatcatt attaaagaaa cgattaatat
    19741 aatgttgaat cctatagtat cacctaattc gtttacacct ttgcctaata tcggagatac
    19801 aaagctttgt attaataatg aaagagatgc ccatatagta aatgaggttc tgttgcaaag
    19861 ttgaatttat agtataattt taacaaaaag gagtcttctg tatgaactat ttcagatata
    19921 aacaatttaa caaggatgtt atcactgtag ctgttggcta ctatctaaga tatgcattga
    19981 gttatcgtga tatatctgaa atattaaggg aacgtggtgt aaacgttcat cattcaacgg
    20041 tctaccgttg ggttcaagaa tatgccccaa ttttatatca aatttggaag aaaaagcata
    20101 aaaaagctta ttacaaatgg cgtattgatg agacgtacat caaaataaaa ggaaaatgga
    20161 gctatttata tcgtgccatt gatgcagagg gacatacatt agatatttgg ttgcgtaagc
    20221 aacgagataa tcattcagca tatgcgttta tcaaacgtct cattaaacaa tttggtaaac
    20281 ctcaaaaggt aattacagat caggcacctt caacgaaggt agcaatggtt aaagtaatta
    20341 aagcttttaa acttaaacct gactgccatt gtacatcgaa atatctgaat aacctcattg
    20401 agcaagatca ccgtcatatt aaagtaagaa agacaaggta tcaaagtatc aatacagcaa
    20461 agaatacttt aaaaggtatt gagtgtattt acgctctata taaaaagaac cgcaggtctc
    20521 ttcagatcta cggattttcg ccatgccacg aaattagcat catgctagca agttaagcga
    20581 acactgacat gataaattag tggttagcta tattttttta ctttgcaaca gaaccagcat
    20641 ttgttttaat atttgttcca aagagccatc atggctttga cagagctctt cttctatgca
    20701 aatgctttta atccgatcca cacgaaaatt cctatattca tttcttagcc tgcaaaaccg
    20761 attaagtacc agttctgttc ataaaacccc agtgatatag gctctatcat tctgctttcc
    20821 ggttcttgcc ctcctgatgc aggatattga attgatatta cccttttatt gcagattgca
    20881 gtctgaattg ctgcaataac gttatccgcc aatgtatttt tctgtccaga tgtgctgtac
    20941 acgttaatac tgttctccaa ctcctgtgca tagttttttt caccatgctt caaaatagat
    21001 ttgattttat acatagctga atcaaaatcc tttataaatg attcatctcc atggcaattt
    21061 aaaaatttcc ctgctgtaat caatgcaccc acttccgccg ctgtaaacat taccggcgga
    21121 agtaggaagc cctctacaag aaaatatcct tttccggcct cagatccaat tggtattccg
    21181 gcttcttcaa gtgtccggat atctctgtaa actgtcctta agcttatatt aaatcgctgt
    21241 gcaatttctt tggcaggaat tatttttttg attgcagctg aataagaata gaggttactc
    21301 tgttaatcct gttcaaattt tattcctcct ctgtgacttc cataaaaagt atatcctatg
    21361 cgttcttaag ctagctgctg ttagtgcttc tcattgcacc ctggttataa aagccatact
    21421 cacaaacctc ttcaccaaaa ctctttacat ctctaatata gaactctatc tagcgaactt
    21481 ttagaaaaga tataaaacat cagagtatgg acagttgcgg atgtacttca gaaaagatta
    21541 gatgtctaaa aagcttgtag ttaaagcttt ttagacatct aaatctaggt actaaaacaa
    21601 ttcatccagt aaaatataat attttatttt ctcccaatca ggcttgatcc ccagtaagtc
    21661 aaaaaatagc tcgacatact gttcttcccc gatatcctcc ctgatcgacc ggacgcagaa
    21721 ggcaatgtca taccacttgt ccgccctgcc gcttctccca agatcaataa agccacttac
    21781 tttgccatct ttcacaaaga tgttgctgtc tcccaggtcg ccgtgggaaa agacaagttc
    21841 ctcttcgggc ttttccgtct ttaaaaaatc atacagctcg cgcggatctt taaatggagt
    21901 gtcttcttcc cagttttcgc aatccacatc ggccagatcg ttattcagta agtaatccaa
    21961 ttcggctaag cggctgtcta agctattcgt atagggacaa tccgatatgt cgatggagtg
    22021 aaagagcctg atgcactccg catacagctc gataatcttt tcagggcttt gttcatcttc
    22081 atactcttcc gagcaaagga cgccatcggc ctcactcatg agcagattgc tccagccatc
    22141 atgccgttca aagtgcagga cctttggaac aggcagcttt ccttccagcc atagcatcat
    22201 gtccttttcc cgttccacat cataggtggt ccctttatac cggctgtccg tcatttttaa
    22261 atataggttt tcattttctc ccaccagctt atatacctta gcaggagaca ttccttccgt
    22321 atcttttacg cagcggtatt tttcgatcag ttttttcaat tccggtgata ttctcatttt
    22381 agccatttat tatttccttc ctcttttcta cagtatttaa agatacccca agaagctaat
    22441 tataacaaga cgaactccaa ttcactgttc cttgcattct aaaaccttaa ataccagaaa
    22501 acagcttttt caaagttggc gtataacata gtatcgacgg agccgatttt gaaaccacaa
    22561 ttatgataga atttacaagc tataaggtta ttgtcctggg tttcaagcat tagtccatgc
    22621 aagtttttat gctttgccca ttctatagat atattgataa gcgcgctgcc tatgccttgc
    22681 cccctgaaat ccttacatac ggcgatatct tctatataag cgtaccggtt ccaatttttt
    22741 cgcagtttaa cttttccgac gcatttatcg tcttggtagt aaagatatat tatcttatca
    22801 gtattgtcaa tatattcaag gcaatctgcc tcctcatcct cttcatcctc ttcgtcttgg
    22861 tagcttttta aatatggcgc ttcatagagt aattctgtaa aggtccaatt ctcgttttca
    22921 tacctcggta taatcttacc tatcacctca aatggttcgc tgggtttatc gatatctttc
    22981 aggtgccctg ctttcatttc tgtaatcact gttcccgcct ctcttctata tcagcggcat
    23041 atgtgctatc caggcagccg gttttaccag tgtatttttt atacatgtcc ctggtatatt
    23101 ttgttatatt cctatcatac tccggatagg cataatgaag cctttccgcc acctcaccgg
    23161 ataccgccct gaacaattga tggcatagaa ataatgcttc ccatatgttt tcataggaat
    23221 ccatccggta ggtggacaaa agtttctccc acaaatcctc ggatatatac ctttcaataa
    23281 acttatagtt cttgcctaca cttcatttaa agcctgtttc gatgccgacc ttccatgata
    23341 tcattctcag cagctcatgg cgaacaatct gattaaaatg atcaatagca aataaaattt
    23401 ccttacggca caatccttta ataacataag gtgttacatt ccaaaattca ttgcagcaat
    23461 catcatactc ccttgcgctt ggctttctta catgataatc tatatcagtc ggaactatgt
    23521 cccttttaat tctacaatct ttatcaatta gaacctttat taatttatcg ccctttaggt
    23581 aattatctaa ctcttccaag ggcaataagg taagatcaat tttattgtaa tcatcaaata
    23641 gctataatag atttagaggt aaagaaatta aatacattga agagcagaaa gattttacaa
    23701 aagagtattt taataaaaat gatggttctg ttgcaaagta aaaaatatag ctaatcacta
    23761 atatatcatg tcagtgttcg tttaacttgc tagcatgatg ctaatttcgt ggcatgggga
    23821 aaatccgtag atctgaagag acctacggtt ctttttatat agagcgtaaa tacattcaat
    23881 accttttaaa gtattctttg ccgtattgat actttgatat cttgtctttc ttactttaat
    23941 atgacggtga tcttgctcaa tgaggttatt cagatatttc gatgtacaat gacagtcagg
    24001 tttaagttta aaagctttaa ttattttagc cattgctgcc ttcgttgaag gtgcctgatc
    24061 tgtaactacc ttttgaggct taccaaattg tttaatgaga cgtttgataa acgcatatgc
    24121 tgaatgatta tctcgttgct tacgcaacca aatatctaat gtatgtccct ctgtatcaat
    24181 ggcacgatat aaatagctcc attttccttt tattttgata tacgtctcat caatacgcca
    24241 tttgtaataa gcttttttat gctttttctt ccaaatttga tataaaattg gggcatattc
    24301 ttgaacccaa cggtagatcg ttgaatgatg aacgtttaca ccacgttctc ttaatatttc
    24361 agatatatca cgatagctca atgcatatct tagatagtag ccaacggcta cagtgataac
    24421 atccttgtta aattgtttat atctgaaata gttcatacag aagactcctt tttgttaaaa
    24481 ttatattata aattcaactt tgcaacagaa cctcctaact gtattaccac cttaaaagta
    24541 gttgcagacg cacttcctaa atcgtcagca gtgtttaacc acatatcatc aacaataatc
    24601 atatgacctg ttgatgatac tggagcaaat tctgtcaacc cttcaactac acctaaaata
    24661 aatgctttaa tctgctctat aaaacccatt tttctcctcc ttttaactta tatcagtttt
    24721 tttaaagtat gagaataata taattacact gaatatagat gtaacaatta tgataattaa
    24781 agataataga aatggataag tattaggtaa tgttcctcta gatatgtctc caactgcagc
    24841 ccaaggaaat aatcctctat gttcagaatt agcagtcatt aaatttatca aagtaattat
    24901 tatggttaaa acaattgtgg gaacataatt tttaaaatat atcgacaaaa taattattgg
    24961 tggagataat atccataata acactccgcc aataacaaat gtaaagaatg aatcaattat
    25021 taaactctgg cttaaccctt gaaaatgcaa tagcatacct agcattaaag ttagcaacca
    25081 tgcaataaca gatagtgttt gaatccacaa gaataataat attattttac ttactaaaaa
    25141 actttctcta gatataggta taattaataa gttttttaaa gtatcttcta tatattctct
    25201 tccaaacaaa taggctatta taaccccata tagaggaggt ccaataatta gcatatgata
    25261 taaactgact tcttcaaata actgtttaaa tacaatatta ggagtcggta ctttcgtccg
    25321 catactaata aaagaagcta caaccaccat aaaaggtgct acgcatgtac ctaaaatact
    25381 tattagaaac atatatgatc tttttaactt aataaattct gtacggagta
//
