LOCUS       CP052429                6890 bp    DNA     circular BCT 04-MAY-2020
DEFINITION  Klebsiella pneumoniae strain C16KP0129 plasmid pC16KP0129-2,
            complete sequence.
ACCESSION   CP052429
VERSION     CP052429.1
DBLINK      BioProject: PRJNA625837
            BioSample: SAMN14609892
KEYWORDS    .
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 6890)
  AUTHORS   Yoon,E.-J., Gwon,B., Liu,C., Kim,D., Won,D., Park,S.G., Choi,J.R.
            and Jeong,S.H.
  TITLE     Built-in CTX-M extended-spectrum beta-lactamase gene in Klebsiella
            pneumoniae ensuring stable propagation of the multidrug-resistant
            pathogen in clinical settings
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6890)
  AUTHORS   Yoon,E.-J., Gwon,B., Liu,C., Kim,D., Won,D., Park,S.G., Choi,J.R.
            and Jeong,S.H.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-APR-2020) Research Institute of Bacterial Resistance,
            Yonsei University College of Medicine, 211, Eonjuro, Gangnam-Gu,
            Seoul 06273, Korea, Republic of
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.13.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100x
            Sequencing Technology             :: Oxford Nanopore and Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 04/27/2020 20:38:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 4.11
            Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region
            Genes (total)                     :: 5,290
            CDSs (total)                      :: 5,168
            Genes (coding)                    :: 5,049
            CDSs (with protein)               :: 5,049
            Genes (RNA)                       :: 122
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 84
            ncRNAs                            :: 13
            Pseudo Genes (total)              :: 119
            CDSs (without protein)            :: 119
            Pseudo Genes (ambiguous residues) :: 0 of 119
            Pseudo Genes (frameshifted)       :: 86 of 119
            Pseudo Genes (incomplete)         :: 23 of 119
            Pseudo Genes (internal stop)      :: 17 of 119
            Pseudo Genes (multiple problems)  :: 6 of 119
            ##Genome-Annotation-Data-END##
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..6890
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="C16KP0129"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="pC16KP0129-2"
                     /geo_loc_name="South Korea: Gangwon"
                     /lat_lon="37.82 N 128.16 E"
                     /collection_date="2016"
                     /collected_by="Kor-GLASS"
     gene            complement(join(6753..6890,1..321))
                     /gene="traD"
                     /locus_tag="HJX04_26415"
     CDS             complement(join(6753..6890,1..321))
                     /gene="traD"
                     /locus_tag="HJX04_26415"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraD"
                     /protein_id="QJK99757.1"
                     /translation="MHENEWLEKRLAYIRGLNAPNEQQRLLLMLAQLSQPTPNDRRKLG
                     VLIRAEKAAERALKARADAAKVLNAERRAVRKARDHELYKAAGLMGVAGVVDRETGRLN
                     VDAGLLVGLLMELAAGTLPENLHQEALKSRGDAAIAAREKKNKTNQAG"
                     /name="traD"
     gene            495..1934
                     /locus_tag="HJX04_26420"
     CDS             495..1934
                     /locus_tag="HJX04_26420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011382089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="QJK99750.1"
                     /translation="MAIARLSMKAGMKGRGADHSAYISREGKYANRLERGERLEATDHG
                     NMPEWAKDNPQQFWLAADAYERKNGTSYREMEIALPRELDSEQREALVRDWTEQELGDK
                     HAYQWAIHVPTAADGGEQPHVHLMFSERQRDGIERDPEQYFKRYNSRNPEAGGSRKGYG
                     EHGGQPRTLEQRREELVALRGRWEAKANEHLERAGQRERIDMRSYTAQGKDAIPEKKQL
                     PSEWRDERKRAEILDFRAAKAEQEQAQKDAGKVLYEHNSAVEHYRGVVAAVPEHRLKNS
                     SPDSIALDLREKLVGQRVDSDPAVLAAREQEEKTGKALENARQERDKTRQEAEQQRQEQ
                     QRWEEENRMRRWLHDKGIKKDERYTGLQQQREKSEQQAQAAVQKEQQAEMQHRQAVTAR
                     EETETDVRQQANEKWFEHHHTAVKEAAAERQRELERQEREQQQAKQAEYQQLIAQQQRQ
                     REQEKEQEHTPERQHGRGMSM"
                     /name="MobA/MobL family protein"
     gene            complement(1961..4066)
                     /locus_tag="HJX04_26425"
     CDS             complement(1961..4066)
                     /locus_tag="HJX04_26425"
                     /inference="COORDINATES: protein motif:HMM:NF024108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="QJK99751.1"
                     /translation="MKKLSLNWSGNVSQSIEKARTLAAEYSRRDVPDNAPSDLRDSASQ
                     GLETSKGFALSGRLLQSELVYGSDVPLAQFGTVLIPLVLAFTTLLLYWLPAWLAFIPSV
                     LWALFAIMTGGFTLGWFAGVLALLLLWGSDISLFSMGGTAQMLQFGTGMTLTLISLAAL
                     PLCHLLRRAERFTIINDDAKAGAIILSASRQAKAREKQTERAARDTSPLIWLGEAQGVT
                     WEKGDIMAPDPASRVALSAADLSTGLLVLGGTGTGKTSGVFRPVIRQWCEHNCGGLLLM
                     DGKGQLPAELAESNRGITLLTPDNPETPVPLIDGLNAEEVAAVLVSVSGKGNDKGSDWT
                     FAAEKQFRFSALLVELAVSVQAAPWTLATIARCVSDTAFRDTLIEAVSARTETLSPELT
                     TAALDFWLKEYPELAKAEGYTSSVQGIVTAWLSPLVGHRKMHGWINAAGGVNPSDVLRG
                     ARYGIGIDSSVYGELCTAAVNGFIKKRLYNEATRRGDNWKADSTNTAAMIVMDEADVLL
                     DETDAGILPRGRSLGLNFVVGLQAVEQAEAAFGGTQNAPKALAMLAQLRSVVALSSTHH
                     TAQYVSDRVGFGLPLEPVSLSTVPDMRYTVLQRAAASPFNDEENEFRSSITLDIPHVIS
                     HTVGKMMDHKNAAGERLQLAKEPKPWISPQECNMLTATEGVAVVVLNRAGAPRRDAIEL
                     VPEYRAG"
                     /name="TraM recognition domain-containing protein"
     gene            complement(4078..4467)
                     /locus_tag="HJX04_26430"
     CDS             complement(4078..4467)
                     /locus_tag="HJX04_26430"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QJK99752.1"
                     /translation="MKKLSVYSRLSRKAGAKIYPNSNPDVHLHKADRIIPVRQEYAGAA
                     AATAGRIAVEVERQTLRSMTYKRLYPWVLALSVLCLLPPFASMGVDMFHAKQAQAEMQR
                     QQKQQLEEMNRRQQERINRLRSGIY"
                     /name="hypothetical protein"
     gene            4516..4677
                     /locus_tag="HJX04_26435"
     CDS             4516..4677
                     /locus_tag="HJX04_26435"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QJK99753.1"
                     /translation="MTEKKQSANARRQAAFKARQREAGRTQRVLWLTDEEVNAVKALLD
                     KMRGDERP"
                     /name="hypothetical protein"
     gene            complement(4685..4984)
                     /locus_tag="HJX04_26440"
     CDS             complement(4685..4984)
                     /locus_tag="HJX04_26440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010848978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="QJK99754.1"
                     /translation="MTYEIDWRPGAVEDMAALFEYLAENASLWDARNVTDRLIAATERL
                     EDYPRLYETDERYGEGVRRISLLGQHVLYEVNDELRRVNILAVVGQRQNPLSVR"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(4974..5237)
                     /locus_tag="HJX04_26445"
     CDS             complement(4974..5237)
                     /locus_tag="HJX04_26445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein"
                     /protein_id="QJK99755.1"
                     /translation="MNSTTHYENANFLRELAESLPRILPDGGADKAALLQRLANEELAQ
                     AEYDERVRAKVAAARADKRPGMSTAQLRQQLQGRYQELSNDL"
                     /name="plasmid stabilization protein"
     gene            complement(5374..6075)
                     /locus_tag="HJX04_26450"
     CDS             complement(5374..6075)
                     /locus_tag="HJX04_26450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001281396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="QJK99756.1"
                     /translation="MSDLIAYKSNALIEASYKLTLQEQRFLLVCISRLKSGEDAPSPDE
                     QKTMTITAAEFHDAFPDMGRQHAEAKLKEAIDRLWDRSVIIKNEEKREEFRWVQYRAQY
                     LKGEAKVEITFSDAIMPYLTQLKGQFTRVVVKNVSSLSSTYSIRIYELLQQFRSTGDRT
                     ISLDDFRSILELEDKYSDFKILNRDLIKPAIAELNEKSDLAVTVETVKKGRTVVALRFR
                     FKEDKQIKMAV"
                     /name="replication initiation protein"
     Typing          complement(5375..6075)
                     /name="rep_cluster_1778"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="98.006"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          496..1931
                     /name="MOBQ"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="98.539"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 ggcatccaca ttgagccgcc cggtttcacg gtcaaccacg ccggccacgc ccatcagacc
       61 agccgccttg tagagttcgt ggtcacgcgc tttgcggacg gcgcgacgtt cggcattcag
      121 cactttagcg gcatcagcgc gagcctttag cgccctctct gcggcttttt cagcacgaat
      181 gagtactccc agcttgcggc ggtcattcgg tgttggctgg gacaactgcg ccagcatcag
      241 caaaaggcgc tgctgttcgt tcggtgcgtt cagtccgcga atatatgcga gccgtttctc
      301 cagccattca ttttcgtgca ttttttcccc cgctgttcgt ttcgtgcctg cataaaacta
      361 ccacagttgc ggcggagggt gtatccttct cggaaatctt cgattttcgg aaggcgcgct
      421 tagtagtttc tccccttcgg tgagaaactg cgcggtgggg caagccccac accccaaatt
      481 tacagggtaa agaaatggcg attgcaagac tcagcatgaa agcgggaatg aaaggccgtg
      541 gcgcagacca ctcggcctac atttcccgtg agggcaagta tgcaaatcgt ctggaacggg
      601 gagagcgtct ggaggccacc gaccacggca atatgccgga gtgggcgaag gacaatccgc
      661 aacagttctg gctggccgcc gatgcgtatg agcgcaagaa cggcacctca taccgtgaga
      721 tggaaatcgc cctgcctcgt gagctggaca gcgaacagcg tgaggcgctt gtcagggact
      781 ggacggagca ggagctgggc gacaaacacg cttatcagtg ggctatccac gttcccaccg
      841 ccgctgacgg aggtgagcag ccacacgtac acctgatgtt ctccgaacgg cagcgggacg
      901 ggattgagcg cgatccagag cagtatttca aacgctataa cagccggaac ccggaagcag
      961 gcgggtcgcg gaaggggtac ggtgagcatg gcggccagcc gcgcacgctg gagcagcggc
     1021 gcgaggaact tgtcgccctg cgcggccgtt gggaggccaa agctaacgaa catcttgagc
     1081 gagccggcca gcgcgaacgt atcgacatgc gcagctatac agcgcagggc aaggacgcca
     1141 ttcctgaaaa aaagcagcta ccgagtgaat ggcgcgacga gcggaagcgt gcagaaatac
     1201 tggatttccg cgctgcaaaa gccgagcagg aacaggcaca gaaagacgcc ggcaaggttc
     1261 tttatgagca caatagcgcg gtagagcact atcgcggcgt tgtggccgcg gtgccggagc
     1321 accggctgaa aaactcctca ccggacagca tcgctctgga tttgcgagaa aaactcgtcg
     1381 ggcagcgcgt tgacagcgat ccggccgtac tggccgcacg ggagcaggaa gaaaaaaccg
     1441 gtaaggcgct ggagaatgcg cggcaggaac gggacaaaac ccggcaggaa gccgagcagc
     1501 agcggcagga gcagcaacga tgggaagaag aaaaccggat gcgccgctgg ctccatgaca
     1561 agggcatcaa aaaggacgag cgttataccg gactgcaaca gcaacgggaa aaatcagagc
     1621 agcaggcaca ggccgccgtg cagaaggagc aacaggcaga aatgcagcac cggcaggccg
     1681 tcactgcgcg ggaagaaacc gaaactgatg tccgtcagca ggccaatgaa aaatggttcg
     1741 agcatcatca tacggccgtg aaagaggctg ccgccgaacg ccagcgggaa cttgagcggc
     1801 aggagcggga gcagcagcag gcaaaacagg ctgaatatca gcagttgatc gcccagcaac
     1861 agcggcaacg tgagcaggaa aaagagcagg agcacacacc ggaacggcag cacgggcgcg
     1921 gaatgagcat gtaaaaaagg caccttgcgg tgcctttttt tcagccggcg cggtattcgg
     1981 gaaccagctc tatcgcatcg cggcggggag cgccggcgcg gttgagaacc acaacggcca
     2041 cgccctccgt cgccgtcagc atgttgcatt cctgcggtga gatccacggc ttaggctctt
     2101 ttgccagctg gagacgttcg ccggcagcat ttttgtgatc catcattttg ccaaccgtat
     2161 gactaatcac atgcggaata tcgagcgtta tcgagctgcg gaactcgttt tcctcgtcgt
     2221 taaacggtga ggccgccgcc cgttgcagta cggtatagcg catgtccggc acggtggaga
     2281 gcgataccgg ctccagtggc agcccgaacc ccacacgatc ggagacatac tgcgcggtgt
     2341 gatgggttga tgacagcgcg acaacggagc gcagctgtgc cagcatcgcc agggcttttg
     2401 gcgcgttctg cgtcccgccg aaagcggctt ccgcctgttc cactgcctgc aagccaacca
     2461 cgaaattcag ccccagtgag cgcccacgcg gcagaatgcc ggcatcggtt tcatcgagca
     2521 gcacatcagc ttcatccatc acaatcatgg ccgctgtatt tgtgctgtcc gctttccagt
     2581 tatcaccgcg ccgcgttgcc tcgttgtaca gccgtttttt gatgaacccg ttaaccgctg
     2641 cggtgcagag ttcgccatat accgatgaat caatccctat gccgtaccgc gccccgcgca
     2701 ggacatcaga agggtttacc cctccggcgg cattaatcca gccgtgcatt ttcctgtgac
     2761 cgaccagcgg agaaagccac gcggtcacaa tcccctgcac agaactggta tacccttcgg
     2821 cttttgccag ttccgggtat tccttgagcc agaaatccag tgcggccgtg gtcagttcag
     2881 gtgacagtgt ttctgtacgg gcgcttacag cctcaatcag cgtgtccctg aatgccgtat
     2941 ctgacacgca gcgggcaata gtggccagcg tccacggtgc ggcctgaacg ctgacggcca
     3001 gctcaacgag cagggcagaa aaacggaact gtttttcggc cgcaaatgtc cagtcagagc
     3061 ctttatcatt ccccttgccg gagacagaaa ccagcacggc ggccacttct tcggcattca
     3121 ggccatcgat cagcgggaca ggcgtttccg ggttatccgg ggtcagcagc gttattcccc
     3181 tgttgctttc ggccagttcg gccggtaact gtccctttcc gtccatcaga agcaggccac
     3241 cgcaattgtg ctcacaccac tgacggataa ccggcctgaa cacgccggac gttttgccgg
     3301 tgccggtgcc accgagaaca agcaatcccg tggacaggtc agcggccgac agggcaacgc
     3361 gtgacgccgg atcgggcgcc ataatatccc ccttctccca tgtcacgccc tgcgcctcac
     3421 ccagccagat cagcggcgag gtgtcgcgtg cggctcgttc tgtctgtttt tcgcgggctt
     3481 ttgcctgacg tgaggcggac agaatgattg cgccggcttt agcgtcatcg ttgatgatgg
     3541 taaagcgctc ggcgcggcgc agaaggtgac agagcggcag agcggccagc gaaatcagcg
     3601 tcagcgtcat accggtgcca aactggagca tctgcgctgt cccgcccatc gaaaacagcg
     3661 aaatatcaga tccccagagc aggagcagcg ccagaacgcc ggcaaaccag cccagcgtaa
     3721 aaccaccggt catgatggca aacagcgccc ataagacgga cggaatgaat gccagccatg
     3781 ccgggagcca gtacagaagc agggttgtga acgccagtac cagcgggatc agcacagtgc
     3841 cgaactgcgc cagcggcaca tctgaaccgt agaccagttc gctttgcagc agacggccag
     3901 acaacgcaaa ccccttgctc gtttccagtc cctgactggc cgagtcgcgc agatcggacg
     3961 gtgcgttgtc gggtacatca cggcgggagt attcggcggc cagtgtgcgg gctttttcga
     4021 tggactgact cacattgcca gaccagttaa gtgacagttt tttcatgttc tgatccctca
     4081 gtaaatgccg ctgcgcaggc gattaattct ttcctgctgc cggcgattca tctcttccag
     4141 ctgttgtttc tgctggcgct gcatttccgc ctgcgcctgt tttgcatgga acatatcgac
     4201 ccccatcgag gcaaacggcg ggagcaggca gagaacggac agcgccagca cccacggata
     4261 caggcgctta taggtcatgc tgcgcagcgt ctggcgctca acttccacag caatgcggcc
     4321 agccgttgcg gcggccgcgc cggcatactc ctggcgcacg gggataatgc gatctgcttt
     4381 atgcaggtga acatcggggt tactgttagg gtatattttc gcgccggctt tccggctaag
     4441 acgtgaataa acagacagtt ttttcatcag aaaccactcc ttaagcgtta ctagtaacgc
     4501 atcggatagt aacgaatgac agagaaaaag caatcagcaa atgccaggcg tcaggcggcg
     4561 tttaaggcca gacagagaga agccggccgc actcagcggg tgctgtggct gaccgatgaa
     4621 gaggtgaacg ccgtcaaggc gttactggat aaaatgcggg gggatgaacg tccgtaaggc
     4681 gttttcagcg taccgataag gggttctgac gctgaccgac cacggccaga atgtttaccc
     4741 gccgtaactc gtcgttcacc tcatacagca catgctggcc gagcaggctg atacgccgga
     4801 cgccctcgcc gtatcgctcg tcggtctcgt acaaacgggg ataatcttcc agtcgttcag
     4861 tggcggctat caggcggtct gtcacgtttc tggcgtccca tagcgaggca ttttcggcca
     4921 gatactcaaa cagggcggcc atatcttcaa ccgcccccgg ccgccagtcg atttcatagg
     4981 tcattgctca gttcctgata gcgtccctgt aactgctggc gcagctgcgc ggtactcatg
     5041 cccggccgct tgtcagcgcg ggcggcggca acctttgcgc gaacccgttc gtcgtattca
     5101 gcctgtgcca gttcttcgtt agcgagtcgc tggagcagag cggccttatc cgcgccgcca
     5161 tctggcagaa tacggggcaa gctctcggcc agttcgcgca gaaaattggc gttttcgtag
     5221 tgggtagtgc tgttcatggt catatctcca ttcacgcgat ttcatcgccg gcagggggct
     5281 gatttaccca ctggcgatct tcatcgctca tgccggcatc gggattgcat tgtgccagaa
     5341 gttcatccag cgtcagcttt ttggtttcgt tattcatacg gccatcttga tctgcttgtc
     5401 ctctttgaac cggaaccgca acgcgacaac ggttcgcccc tttttcaccg tctcgacggt
     5461 gacggccaga tcgctttttt cgttcagctc agcgatggcc ggttttatta agtctctgtt
     5521 caatatctta aaatcagaat atttatcttc cagttccagt atggatcgga agtcatcgag
     5581 tgaaatagtt ctgtcaccgg tgctgcggaa ctgctggagc agctcgtaaa tgcggatgct
     5641 gtaggtgctg gagaggctgg agacgttctt caccactacc cgcgtaaact gccccttgag
     5701 ctgtgtcaga tagggcatga tggcatcgga gaaggtgatc tctacttttg cctcaccttt
     5761 gagatactgc gcccggtact gcacccagcg gaactcctcg cgcttctcct cgtttttgat
     5821 gatgactgac ctgtcccaga ggcgatctat cgcttccttg agcttggctt cagcgtgctg
     5881 ccgtcccata tcaggaaaag catcatgaaa ctctgcggcc gtgatggtca tggttttttg
     5941 ttcatccggc gaaggggcat cttccccgga tttcaggcgg ctgatacaga ccagcaggaa
     6001 gcgctgttcc tgcaaggtga gcttgtaact ggcctcgata agggcgttgg atttgtaggc
     6061 tatcaaatca gacatgagta atttatgttc ttatggtgag tgtttatttt gttttatcac
     6121 ccaatcaaaa ggtgatcaat attttttttt actcaccttt ttttgtggat ataacccccg
     6181 atttcctcac ctataacccc cgatttcctc acctataacc cccgatttcc tcacctatct
     6241 tgccagaacg ttattaaaat cattggctta cgagaccgaa aaaggtttta aaaaagaaga
     6301 tctaaaaaaa agatcttaaa aacttaacgg cggctctgtg gataaaacga agccacgaaa
     6361 aaaaacatca aaataaacag taggttatga atatgcctat tctgcagggc gctgaatggc
     6421 cgtaaatccc tgtgaataac gcgctatggc aggaggtagc acccgcccgg acgggcgggc
     6481 aaatcgctga aaggctgtac gtcttcgacc gtcaggatct ggtgtcgctt cactggcaga
     6541 gaaggggaaa cccggtcttt tcaggatgga ggggcggcag tcgtcacagc cgggaaccag
     6601 cactaaattg gcggatggct ctaaaacgct ctataacgca ctgtgagcgt ttttttcttt
     6661 tccatgtacg tttccctaac cgaaggcaaa aaaaagccgc aggatgattt ctgcggcttc
     6721 tcagggctat tggcaaacaa gtgtgaggtt cattagccag cctgattcgt tttatttttt
     6781 ttctcacggg cagcgatagc agcatcaccg cgagatttaa gtgcttcctg gtgcaggttt
     6841 tccggcagtg taccggcagc caactccatg agcaatccga caagcaggcc
//
