LOCUS       CP052361                6912 bp    DNA     circular BCT 04-MAY-2020
DEFINITION  Klebsiella pneumoniae strain D16KP0144 plasmid pD16KP0144-5,
            complete sequence.
ACCESSION   CP052361
VERSION     CP052361.1
DBLINK      BioProject: PRJNA625837
            BioSample: SAMN14609913
KEYWORDS    .
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 6912)
  AUTHORS   Yoon,E.-J., Gwon,B., Liu,C., Kim,D., Won,D., Park,S.G., Choi,J.R.
            and Jeong,S.H.
  TITLE     Built-in CTX-M extended-spectrum beta-lactamase gene in Klebsiella
            pneumoniae ensuring stable propagation of the multidrug-resistant
            pathogen in clinical settings
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6912)
  AUTHORS   Yoon,E.-J., Gwon,B., Liu,C., Kim,D., Won,D., Park,S.G., Choi,J.R.
            and Jeong,S.H.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-APR-2020) Research Institute of Bacterial Resistance,
            Yonsei University College of Medicine, 211, Eonjuro, Gangnam-Gu,
            Seoul 06273, Korea, Republic of
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.13.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100x
            Sequencing Technology             :: Oxford Nanopore and Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 04/27/2020 21:06:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 4.11
            Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region
            Genes (total)                     :: 5,610
            CDSs (total)                      :: 5,484
            Genes (coding)                    :: 5,312
            CDSs (with protein)               :: 5,312
            Genes (RNA)                       :: 126
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 15
            Pseudo Genes (total)              :: 172
            CDSs (without protein)            :: 172
            Pseudo Genes (ambiguous residues) :: 0 of 172
            Pseudo Genes (frameshifted)       :: 82 of 172
            Pseudo Genes (incomplete)         :: 82 of 172
            Pseudo Genes (internal stop)      :: 33 of 172
            Pseudo Genes (multiple problems)  :: 23 of 172
            ##Genome-Annotation-Data-END##
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..6912
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="D16KP0144"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="pD16KP0144-5"
                     /geo_loc_name="South Korea: Chungbuk"
                     /lat_lon="36.80 N 127.70 E"
                     /collection_date="2016"
                     /collected_by="Kor-GLASS"
     gene            complement(join(5242..6912,1..435))
                     /locus_tag="HJX25_28015"
     CDS             complement(join(5242..6912,1..435))
                     /locus_tag="HJX25_28015"
                     /inference="COORDINATES: protein motif:HMM:NF024108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="QJJ93997.1"
                     /translation="MKKLSLNWSGNVSQSIEKARTLAAEYSRRDVPDNAPSDLRDSASQ
                     GLETSKGFALSGRLLQSELVYGSDVPLAQFGTVLIPLVLAFTTLLLYWLPAWLAFIPSV
                     LWALFAIMTGGFTLGWFAGVLALLLLWGSDISLFSMGGTAQMLQFGTGMTLTLISLAAL
                     PLCHLLRRAERFTIINDDAKAGAIILSASRQAKAREKQTERAARDTSPLIWLGEAQGVT
                     WEKGDIMAPDPASRVALSAADLSTGLLVLGGTGTGKTSGVFRPVIRQWCEHNCGGLLLM
                     DGKGQLPAELAESNRGITLLTPDNPETPVPLIDGLNAEEVAAVLVSVSGKGNDKGSDWT
                     FAAEKQFRFSALLVELAVSVQAAPWTLATIARCVSDTAFRDTLIEAVSARTETLSPELT
                     TAALDFWLKEYPELAKAEGYTSSVQGIVTAWLSPLVGHRKMHGWINAAGGVNPSDVLRG
                     ARYGIGIDSSVYGELCTAAVNGFIKKRLYNEATRRGDNWKADSTNTAAMIVMDEADVLL
                     DETDAGILPRGRSLGLNFVVGLQAVEQAEAAFGGTQNAPKALAMLAQLRSVVALSSTHH
                     TAQYVSDRVGFGLPLEPVSLSTVPDMRYTVLQRAAASPFNDEENEFRSSITLDIPHVIS
                     HTVGKMMDHKNAAGERLQLAKEPKPWISPQECNMLTATEGVAVVVLNRAGAPRRDAIEL
                     VPEYRAG"
                     /name="TraM recognition domain-containing protein"
     gene            complement(447..836)
                     /locus_tag="HJX25_28020"
     CDS             complement(447..836)
                     /locus_tag="HJX25_28020"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QJJ93990.1"
                     /translation="MKKLSVYSRLSRKAGAKIYPNSNPDVHLHKADRIIPVRQEYAGAA
                     AATAGRIAVEVERQTLRSMTYKRLYPWVLALSVLCLLPPFASMGVDMFHAKQAQAEMQR
                     QQKQQLEEMNRRQQERINRLRSGIY"
                     /name="hypothetical protein"
     gene            885..1046
                     /locus_tag="HJX25_28025"
     CDS             885..1046
                     /locus_tag="HJX25_28025"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QJJ93991.1"
                     /translation="MTEKKQSANARRQAAFKARQREAGRTQRVLWLTDEEVNAVKALLD
                     KMRGDERP"
                     /name="hypothetical protein"
     gene            complement(1054..1353)
                     /locus_tag="HJX25_28030"
     CDS             complement(1054..1353)
                     /locus_tag="HJX25_28030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010848978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="QJJ93992.1"
                     /translation="MTYEIDWRPGAVEDMAALFEYLAENASLWDARNVTDRLIAATERL
                     EDYPRLYETDERYGEGVRRISLLGQHVLYEVNDELRRVNILAVVGQRQNPLSVR"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(1343..1606)
                     /locus_tag="HJX25_28035"
     CDS             complement(1343..1606)
                     /locus_tag="HJX25_28035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein"
                     /protein_id="QJJ93993.1"
                     /translation="MNSTTHYENANFLRELAESLPRILPDGGADKAALLQRLANEELAQ
                     AEYDERVRAKVAAARADKRPGMSTAQLRQQLQGRYQELSNDL"
                     /name="plasmid stabilization protein"
     gene            complement(1743..2444)
                     /locus_tag="HJX25_28040"
     CDS             complement(1743..2444)
                     /locus_tag="HJX25_28040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001281396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="QJJ93994.1"
                     /translation="MSDLIAYKSNALIEASYKLTLQEQRFLLVCISRLKSGEDAPSPDE
                     QKTMTITAAEFHDAFPDMGRQHAEAKLKEAIDRLWDRSVIIKNEEKREEFRWVQYRAQY
                     LKGEAKVEITFSDAIMPYLTQLKGQFTRVVVKNVSSLSSTYSIRIYELLQQFRSTGDRT
                     ISLDDFRSILELEDKYSDFKILNRDLIKPAIAELNEKSDLAVTVETVKKGRTVVALRFR
                     FKEDKQIKMAV"
                     /name="replication initiation protein"
     gene            complement(3144..3602)
                     /gene="traD"
                     /locus_tag="HJX25_28045"
     CDS             complement(3144..3602)
                     /gene="traD"
                     /locus_tag="HJX25_28045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011382088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraD"
                     /protein_id="QJJ93995.1"
                     /translation="MHENEWLEKRLAYIRGLNAPNEQQRLLLMLAQLSQPTPNDRRKLG
                     VLIRAEKAAERALKARADAAKVLNAERRAVRKARDHELYKAAGLMGVAGVVDRETGRLN
                     VDAGLLVGLLMELAAGTLPENLHQEALKSRGDAAIAAREKKNKTNQAG"
                     /name="traD"
     gene            3776..5215
                     /locus_tag="HJX25_28050"
     CDS             3776..5215
                     /locus_tag="HJX25_28050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011382089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="QJJ93996.1"
                     /translation="MAIARLSMKAGMKGRGADHSAYISREGKYANRLERGERLEATDHG
                     NMPEWAKDNPQQFWLAADAYERKNGTSYREMEIALPRELDSEQREALVRDWTEQELGDK
                     HAYQWAIHVPTAADGGEQPHVHLMFSERQRDGIERDPEQYFKRYNSRNPEAGGSRKGYG
                     EHGGQPRTLEQRREELVALRGRWEAKANEHLERAGQRERIDMRSYTAQGKDAIPEKKQL
                     PSEWRDERKRAEILDFRAAKAEQEQAQKDAGKVLYEHNSAVEHYRGVVAAVPEHRLKNS
                     SPDSIALDLREKLVGQRVDSDPAVLAAREQEEKTGKALENARQERDKTRQEAEQQRQEQ
                     QRWEEENRMRRWLHDKGIKKDERYTGLQQQREKSEQQAQAAVQKEQQAEMQHRQAVTAR
                     EETETDVRQQANEKWFEHHHTAVKEAAAERQRELERQEREQQQAKQAEYQQLIAQQQRQ
                     REQEKEQEHTPERQHGRGMSM"
                     /name="MobA/MobL family protein"
     Typing          complement(1744..2444)
                     /name="rep_cluster_1778"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="98.006"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          3777..5212
                     /name="MOBQ"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="98.539"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 ctgcgctgtc ccgcccatcg aaaacagcga aatatcagat ccccagagca ggagcagcgc
       61 cagaacgccg gcaaaccagc ccagcgtaaa accaccggtc atgatggcaa acagcgccca
      121 taagacggac ggaatgaatg ccagccatgc cgggagccag tacagaagca gggttgtgaa
      181 cgccagtacc agcgggatca gcacagtgcc gaactgcgcc agcggcacat ctgaaccgta
      241 gaccagttcg ctttgcagca gacggccaga caacgcaaac cccttgctcg tttccagtcc
      301 ctgactggcc gagtcgcgca gatcggacgg tgcgttgtcg ggtacatcac ggcgggagta
      361 ttcggcggcc agtgtgcggg ctttttcgat ggactgactc acattgccag accagttaag
      421 tgacagtttt ttcatgttct gatccctcag taaatgccgc tgcgcaggcg attaattctt
      481 tcctgctgcc ggcgattcat ctcttccagc tgttgtttct gctggcgctg catttccgcc
      541 tgcgcctgtt ttgcatggaa catatcgacc cccatcgagg caaacggcgg gagcaggcag
      601 agaacggaca gcgccagcac ccacggatac aggcgcttat aggtcatgct gcgcagcgtc
      661 tggcgctcaa cttccacagc aatgcggcca gccgttgcgg cggccgcgcc ggcatactcc
      721 tggcgcacgg ggataatgcg atctgcttta tgcaggtgaa catcggggtt actgttaggg
      781 tatattttcg cgccggcttt ccggctaaga cgtgaataaa cagacagttt tttcatcaga
      841 aaccactcct taagcgttac tagtaacgca tcggatagta acgaatgaca gagaaaaagc
      901 aatcagcaaa tgccaggcgt caggcggcgt ttaaggccag acagagagaa gccggccgca
      961 ctcagcgggt gctgtggctg accgatgaag aggtgaacgc cgtcaaggcg ttactggata
     1021 aaatgcgggg ggatgaacgt ccgtaaggcg ttttcagcgt accgataagg ggttctgacg
     1081 ctgaccgacc acggccagaa tgtttacccg ccgtaactcg tcgttcacct catacagcac
     1141 atgctggccg agcaggctga tacgccggac gccctcgccg tatcgctcgt cggtctcgta
     1201 caaacgggga taatcttcca gtcgttcagt ggcggctatc aggcggtctg tcacgtttct
     1261 ggcgtcccat agcgaggcat tttcggccag atactcaaac agggcggcca tatcttcaac
     1321 cgcccccggc cgccagtcga tttcataggt cattgctcag ttcctgatag cgtccctgta
     1381 actgctggcg cagctgcgcg gtactcatgc ccggccgctt gtcagcgcgg gcggcggcaa
     1441 cctttgcgcg aacccgttcg tcgtattcag cctgtgccag ttcttcgtta gcgagtcgct
     1501 ggagcagagc ggccttatcc gcgccgccat ctggcagaat acggggcaag ctctcggcca
     1561 gttcgcgcag aaaattggcg ttttcgtagt gggtagtgct gttcatggtc atatctccat
     1621 tcacgcgatt tcatcgccgg cagggggctg atttacccac tggcgatctt catcgctcat
     1681 gccggcatcg ggattgcatt gtgccagaag ttcatccagc gtcagctttt tggtttcgtt
     1741 attcatacgg ccatcttgat ctgcttgtcc tctttgaacc ggaaccgcaa cgcgacaacg
     1801 gttcgcccct ttttcaccgt ctcgacggtg acggccagat cgcttttttc gttcagctca
     1861 gcgatggccg gttttattaa gtctctgttc aatatcttaa aatcagaata tttatcttcc
     1921 agttccagta tggatcggaa gtcatcgagt gaaatagttc tgtcaccggt gctgcggaac
     1981 tgctggagca gctcgtaaat gcggatgctg taggtgctgg agaggctgga gacgttcttc
     2041 accactaccc gcgtaaactg ccccttgagc tgtgtcagat agggcatgat ggcatcggag
     2101 aaggtgatct ctacttttgc ctcacctttg agatactgcg cccggtactg cacccagcgg
     2161 aactcctcgc gcttctcctc gtttttgatg atgactgacc tgtcccagag gcgatctatc
     2221 gcttccttga gcttggcttc agcgtgctgc cgtcccatat caggaaaagc atcatgaaac
     2281 tctgcggccg tgatggtcat ggttttttgt tcatccggcg aaggggcatc ttccccggat
     2341 ttcaggcggc tgatacagac cagcaggaag cgctgttcct gcaaggtgag cttgtaactg
     2401 gcctcgataa gggcgttgga tttgtaggct atcaaatcag acatgagtaa tttatgttct
     2461 tatggtgagt gtttattttg ttttatcacc caatcaaaag gtgatcaata ttttttttta
     2521 ctcacctttt tttgtggata taacccccga tttcctcacc tataaccccc gatttcctca
     2581 cctataaccc ccgatttcct cacctataac ccccgatttc ctcacctatc ttgccagaac
     2641 gttattaaaa tcattggctt acgagaccga aaaaggtttt aaaaaagaag atctaaaaaa
     2701 aagatcttaa aaacttaacg gcggctctgt ggataaaacg aagccacgaa aaaaaacatc
     2761 aaaataaaca gtaggttatg aatatgccta ttctgcaggg cgctgaatgg ccgtaaatcc
     2821 ctgtgaataa cgcgctatgg caggaggtag cacccgcccg gacgggcggg caaatcgctg
     2881 aaaggctgta cgtcttcgac cgtcaggatc tggtgtcgct tcactggcag agaaggggaa
     2941 acccggtctt ttcaggatgg aggggcggca gtcgtcacag ccgggaacca gcactaaatt
     3001 ggcggatggc tctaaaacgc tctataacgc actgtgagcg tttttttctt ttccctgtac
     3061 gtttccctaa ccgaaggcaa aaaaaagccg caggatgatt tctgcggctt ctcagggcta
     3121 ttggcaaaca agtgtgaggt tcattagcca gcctgattcg ttttattttt tttctcacgg
     3181 gcagcgatag cagcatcacc gcgagattta agtgcttcct ggtgcaggtt ttccggcagt
     3241 gtaccggcag ccaactccat gagcaatccg acaagcaggc cggcatccac attgagccgc
     3301 ccggtttcac ggtcaaccac gccggccacg cccatcagac cagccgcctt gtagagttcg
     3361 tggtcacgcg ctttgcggac ggcgcgacgt tcggcattca gcactttagc ggcatcagcg
     3421 cgagccttta gcgccctctc tgcggctttt tcagcacgaa tgagtactcc cagcttgcgg
     3481 cggtcattcg gtgttggctg ggacaactgc gccagcatca gcaaaaggcg ctgctgttcg
     3541 ttcggtgcgt tcagtccgcg aatatatgcg agccgtttct ccagccattc attttcgtgc
     3601 attttttccc ccgctgttcg tttcgtgcct gcataaaact accacagttg cggcggaggg
     3661 tgtatccttc tcggaaatct tcgattttcg gaaggcgcgc ttagtagttt ctccccttcg
     3721 gtgagaaact gcgcggtggg gcaagcccca caccccaaat ttacagggta aagaaatggc
     3781 gattgcaaga ctcagcatga aagcgggaat gaaaggccgt ggcgcagacc actcggccta
     3841 catttcccgt gagggcaagt atgcaaatcg tctggaacgg ggagagcgtc tggaggccac
     3901 cgaccacggc aatatgccgg agtgggcgaa ggacaatccg caacagttct ggctggccgc
     3961 cgatgcgtat gagcgcaaga acggcacctc ataccgtgag atggaaatcg ccctgcctcg
     4021 tgagctggac agcgaacagc gtgaggcgct tgtcagggac tggacggagc aggagctggg
     4081 cgacaaacac gcttatcagt gggctatcca cgttcccacc gccgctgacg gaggtgagca
     4141 gccacacgta cacctgatgt tctccgaacg gcagcgggac gggattgagc gcgatccaga
     4201 gcagtatttc aaacgctata acagccggaa cccggaagca ggcgggtcgc ggaaggggta
     4261 cggtgagcat ggcggccagc cgcgcacgct ggagcagcgg cgcgaggaac ttgtcgccct
     4321 gcgcggccgt tgggaggcca aagctaacga acatcttgag cgagccggcc agcgcgaacg
     4381 tatcgacatg cgcagctata cagcgcaggg caaggacgcc attcctgaaa aaaagcagct
     4441 accgagtgaa tggcgcgacg agcggaagcg tgcagaaata ctggatttcc gcgctgcaaa
     4501 agccgagcag gaacaggcac agaaagacgc cggcaaggtt ctttatgagc acaatagcgc
     4561 ggtagagcac tatcgcggcg ttgtggccgc ggtgccggag caccggctga aaaactcctc
     4621 accggacagc atcgctctgg atttgcgaga aaaactcgtc gggcagcgcg ttgacagcga
     4681 tccggccgta ctggccgcac gggagcagga agaaaaaacc ggtaaggcgc tggagaatgc
     4741 gcggcaggaa cgggacaaaa cccggcagga agccgagcag cagcggcagg agcagcaacg
     4801 atgggaagaa gaaaaccgga tgcgccgctg gctccatgac aagggcatca aaaaggacga
     4861 gcgttatacc ggactgcaac agcaacggga aaaatcagag cagcaggcac aggccgccgt
     4921 gcagaaggag caacaggcag aaatgcagca ccggcaggcc gtcactgcgc gggaagaaac
     4981 cgaaactgat gtccgtcagc aggccaatga aaaatggttc gagcatcatc atacggccgt
     5041 gaaagaggct gccgccgaac gccagcggga acttgagcgg caggagcggg agcagcagca
     5101 ggcaaaacag gctgaatatc agcagttgat cgcccagcaa cagcggcaac gtgagcagga
     5161 aaaagagcag gagcacacac cggaacggca gcacgggcgc ggaatgagca tgtaaaaaag
     5221 gcaccttgcg gtgccttttt ttcagccggc gcggtattcg ggaaccagct ctatcgcatc
     5281 gcggcgggga gcgccggcgc ggttgagaac cacaacggcc acgccctccg tcgccgtcag
     5341 catgttgcat tcctgcggtg agatccacgg cttaggctct tttgccagct ggagacgttc
     5401 gccggcagca tttttgtgat ccatcatttt gccaaccgta tgactaatca catgcggaat
     5461 atcgagcgtt atcgagctgc ggaactcgtt ttcctcgtcg ttaaacggtg aggccgccgc
     5521 ccgttgcagt acggtatagc gcatgtccgg cacggtggag agcgataccg gctccagtgg
     5581 cagcccgaac cccacacgat cggagacata ctgcgcggtg tgatgggttg atgacagcgc
     5641 gacaacggag cgcagctgtg ccagcatcgc cagggctttt ggcgcgttct gcgtcccgcc
     5701 gaaagcggct tccgcctgtt ccactgcctg caagccaacc acgaaattca gccccagtga
     5761 gcgcccacgc ggcagaatgc cggcatcggt ttcatcgagc agcacatcag cttcatccat
     5821 cacaatcatg gccgctgtat ttgtgctgtc cgctttccag ttatcaccgc gccgcgttgc
     5881 ctcgttgtac agccgttttt tgatgaaccc gttaaccgct gcggtgcaga gttcgccata
     5941 taccgatgaa tcaatcccta tgccgtaccg cgccccgcgc aggacatcag aagggtttac
     6001 ccctccggcg gcattaatcc agccgtgcat tttcctgtga ccgaccagcg gagaaagcca
     6061 cgcggtcaca atcccctgca cagaactggt atacccttcg gcttttgcca gttccgggta
     6121 ttccttgagc cagaaatcca gtgcggccgt ggtcagttca ggtgacagtg tttctgtacg
     6181 ggcgcttaca gcctcaatca gcgtgtccct gaatgccgta tctgacacgc agcgggcaat
     6241 agtggccagc gtccacggtg cggcctgaac gctgacggcc agctcaacga gcagggcaga
     6301 aaaacggaac tgtttttcgg ccgcaaatgt ccagtcagag cctttatcat tccccttgcc
     6361 ggagacagaa accagcacgg cggccacttc ttcggcattc aggccatcga tcagcgggac
     6421 aggcgtttcc gggttatccg gggtcagcag cgttattccc ctgttgcttt cggccagttc
     6481 ggccggtaac tgtccctttc cgtccatcag aagcaggcca ccgcaattgt gctcacacca
     6541 ctgacggata accggcctga acacgccgga cgttttgccg gtgccggtgc caccgagaac
     6601 aagcaatccc gtggacaggt cagcggccga cagggcaacg cgtgacgccg gatcgggcgc
     6661 cataatatcc cccttctccc atgtcacgcc ctgcgcctca cccagccaga tcagcggcga
     6721 ggtgtcgcgt gcggctcgtt ctgtctgttt ttcgcgggct tttgcctgac gtgaggcgga
     6781 cagaatgatt gcgccggctt tagcgtcatc gttgatgatg gtaaagcgct cggcgcggcg
     6841 cagaaggtga cagagcggca gagcggccag cgaaatcagc gtcagcgtca taccggtgcc
     6901 aaactggagc at
//
