LOCUS       CP052014               28778 bp    DNA     circular BCT 24-SEP-2020
DEFINITION  Staphylococcus aureus strain ER06206.3 plasmid pER06206.3A.2,
            complete sequence.
ACCESSION   CP052014
VERSION     CP052014.1
DBLINK      BioProject: PRJNA470993
            BioSample: SAMN14669386
KEYWORDS    .
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 28778)
  AUTHORS   Caban,A.B., Pak,T., Kumaresh,A., Dupper,A., Chacko,K.,
            Sullivan,M.J., Altman,D.R. and van Bakel,H.
  TITLE     PathoSPOT genomic surveillance reveals prolonged under the radar
            outbreaks of nosocomial methicillin resistant S. aureus bloodstream
            infections
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 28778)
  AUTHORS   Caban,A.B., Pak,T., Kumaresh,A., Dupper,A., Chacko,K.,
            Sullivan,M.J., Altman,D.R. and van Bakel,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-APR-2020) Genetics and Genomic Sciences, Icahn School
            of Medicine, One Gustave L. Levy Place Box 1498, New York, NY 10029,
            USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.3.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 465.995174734356x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 04/23/2020 11:05:26
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 4.11
            Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region
            Genes (total)                     :: 2,971
            CDSs (total)                      :: 2,889
            Genes (coding)                    :: 2,821
            CDSs (with protein)               :: 2,821
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 42 of 68
            Pseudo Genes (incomplete)         :: 26 of 68
            Pseudo Genes (internal stop)      :: 15 of 68
            Pseudo Genes (multiple problems)  :: 15 of 68
            ##Genome-Annotation-Data-END##
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..28778
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="ER06206.3"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="pER06206.3A.2"
                     /geo_loc_name="USA:New York City"
                     /lat_lon="40.7903114 N 73.9528738 W"
                     /collection_date="2016"
                     /collected_by="Mount Sinai Hospital"
     gene            join(28778,1..1040)
                     /locus_tag="HIK46_14695"
     CDS             join(28778,1..1040)
                     /locus_tag="HIK46_14695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="parM protein"
                     /protein_id="QOC01620.1"
                     /translation="MSEIYVMALDFGNGFVKGKINDETFVVKSRIGKKTNSDSQLKGFV
                     ENKLDVSEFIINGNNDEILLFGKDLDKVTNNGKDTASTNDRYNYQSFKDLVECSIGLLA
                     REVPDEVVNVVIATGMPSNEIGTEKQKKFEKILNKNRLIEVDGISKTINVKGIKVIAQP
                     MGTLLDLHMDNGKVFKRFTEGKYSVLDFGSGTTIIDTYQNMKRVGEESFVINKGMIDFY
                     KRIATHVQRKAGGTPVTPRQIEEGLELMQCKVSARETIDFREDFYNEQDNVTQEVLSKF
                     ETVVGNFNSIDRIVVTGGGANIYFDVLSHYYPNVFEKTEESQLSNVRGYEKLGDLLRQK
                     VENEGK"
                     /name="parM protein"
     gene            1043..1399
                     /locus_tag="HIK46_14700"
     CDS             1043..1399
                     /locus_tag="HIK46_14700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid segregation protein ParR"
                     /protein_id="QOC01621.1"
                     /translation="MKKKETQHLLKIKKEDYPQIFDFLEGLPRGTKTAHIREALLRYIA
                     DEGENPRIPTKSRKNSVYVRSEQNDDYNVTSKTKESYHDYMKRQQLTNISDSINDTDSN
                     KKDEEFVNINIDDL"
                     /name="plasmid segregation protein ParR"
     gene            complement(1402..1662)
                     /locus_tag="HIK46_14705"
     CDS             complement(1402..1662)
                     /locus_tag="HIK46_14705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="QOC01622.1"
                     /translation="MNDYDVNQLYRYICLEIKNQRQMLNKRQEEVAFDLNMSAGYLSRI
                     ENGKIKKLSLYTLLLLSDYYGIPFEKVVRNAKYKLELDEEM"
                     /name="helix-turn-helix transcriptional regulator"
     gene            2028..3005
                     /locus_tag="HIK46_14710"
     CDS             2028..3005
                     /locus_tag="HIK46_14710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002471380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="QOC01650.1"
                     /translation="MMSTKFYIQENFRERFYQLPKVFFTNPNYQKLSNDAKIAYAILRD
                     RLELSIKNNWIDEENAIFFIYTNENLMSILNLGKNKVINVKKELEEVNLLEQKRQGLNK
                     PNKLYLMKPIITEKDIYTIKNEETANETSNDREVYNSNFQRFAKQTSRSCSNKPQEVAQ
                     INSSDTDISDTDISDTDISDMNYMHDNYDTEVNNYNSHSNHSNNFHQKQFDIDSVKELE
                     LQEFPEYLKSYLLNFDLDDLKHIKNIILKAKKSFNNRVGQEGYHYMLEDIEAELVSVLK
                     RLKGYMVRKNEKVEDMQSYLMRSIINEIEDYHSLNLRREAFNHF"
                     /name="replication initiator protein A"
     gene            complement(3099..3278)
                     /locus_tag="HIK46_14715"
     CDS             complement(3099..3278)
                     /locus_tag="HIK46_14715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="regulator"
                     /protein_id="QOC01623.1"
                     /translation="MTLNYNQSKVNKTSLHLLVDPDIKKRIAQIANKGEFDNISQAGRY
                     ILKKGLEVVEKENI"
                     /name="regulator"
     gene            3422..4390
                     /locus_tag="HIK46_14720"
     CDS             3422..4390
                     /locus_tag="HIK46_14720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transfer complex protein TraA"
                     /protein_id="QOC01624.1"
                     /translation="MDNVAMRYRIEKYRKKEEYSKKNQQNYKTNFGIKDNETSTFNVKG
                     IATDRKENKLILAEDKQDNQKLLMYANKNNDLYYLNSGSSYKEAVQNTFGKKVNYEVIE
                     DELFIYNSKNKSLNNYEQLNNYHLNDKQIEYDKPLEEERKRRLTDEHKISSQAKEDLAI
                     SLGLSATAFKNDSNITDIEKVTDNESMITIENEINGKTEHLISNFKDDFVSNVKEKLNV
                     SPSVRLGFEELKNASMQIAMGFTEFYGARYDESTLERDPKVVLTEKGYSLSTFDKNGNK
                     KEITTADTFEEAVKLSKEMKNDNSIELKSNELEQELQRNKG"
                     /name="transfer complex protein TraA"
     gene            4407..4721
                     /locus_tag="HIK46_14725"
     CDS             4407..4721
                     /locus_tag="HIK46_14725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017466649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QOC01625.1"
                     /translation="MFKKFSISALYITFLSYVLTSDVLGANPGAKIEQGLQKVQTFLTG
                     IIVAVGICAGVWIVIKKLPGIDDPMVKNEMFRGVGMVLAGVGVGAALVWLVPWVYNLFQ
                     "
                     /name="hypothetical protein"
     gene            4780..5184
                     /locus_tag="HIK46_14730"
     CDS             4780..5184
                     /locus_tag="HIK46_14730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000110157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1097 domain-containing protein"
                     /protein_id="QOC01626.1"
                     /translation="MATEQDVKDVLLDMLGEEKKVKTNKIPRNVDASYKVALGLNLKEL
                     AISVIPPVIFMAIGFIAIALMNLLTIFMGFTVFITGLVIFLTIYALLAMRPIPSKENIR
                     MIDHVKQQQNFTKRQKVFFYGRKEEGVDDV"
                     /name="DUF1097 domain-containing protein"
     gene            5177..5848
                     /locus_tag="HIK46_14735"
     CDS             5177..5848
                     /locus_tag="HIK46_14735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="traD"
                     /protein_id="QOC01627.1"
                     /translation="MFKKKKKQRNEQSFEIINRYIKGDGKNQTIQEDSLIAGFYKDYVV
                     TKDGYISGGLNISGVNTELLTKFEQNDLLEEYSSYISNSIYDEPMFKTITEPVNIQNYI
                     KLLYREVILDMKEHDNKPSRRGQLIASRILFLQEKLSKGEMSTKKHYVFMKEKITENTV
                     AQLDHAVNRLHEKLNINKEAIKQAFSHYGLEVRPIYQQEYLNQFYALYDYKSYNEYHLS
                     N"
                     /name="traD"
     gene            5865..7877
                     /locus_tag="HIK46_14740"
     CDS             5865..7877
                     /locus_tag="HIK46_14740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000874919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="QOC01628.1"
                     /translation="MLGFTNKKQKQEKSKVNNEAFEKLTEVLDTDSIDSIYPFSWIEKK
                     SHIETGENFFKNLLVVDYPDSAKGTYLSNLLKKNGNVEITQFIRPANIDRMIDHLNNSI
                     KNKRAERLRTTDPKRNATIKREIDSSEKQLDKFLDEKTNFMYMYIYITLKADSYEKIQA
                     LEKDIKRTLTRLRLKTHTPTNAMRESFHTVLPINRNFLAPFTQQNMDTATAGHFFMFDD
                     SEIIDLSPNTSVFGINKNTDSLVAVDFNNKEKTLNKNMTIIGTSGVGKSTLNMRIILDN
                     IKKKIRQFIIDPEDEFSAITKYYGGTVVNISTSSNIKINPFEIFSEEVFEKEDESDNET
                     KSDVLTDSSEEENYIDTIVRSKIGKLKTFFRVLKDEISQTEISVLSSTLRKLYQKKGFT
                     GNAKLSDFTSKDYPTLTELYNELKNLDKEKYEILKDLTLIIEDYTIEHGTTTIFDGYTN
                     IKLDNDIITFNLKPLQTEKDVQSAAYLNIFSFLWDEITKDRTTETVLMTDELHFLATNE
                     YSLDFYYQAYKRIRKYSGGAIASTQQIKDILRTSREIGSAIIENSHTKFFFGMDNVGVE
                     DVVDKLGLKFSKQEISHLTKKKKGEALLLYGTQRAFIKIELDKEEIRLWNNDLYEKTYN
                     ESASIEPNYVEQLGLSDIDLAELEEELRQYEMIYE"
                     /name="DUF87 domain-containing protein"
     gene            7895..9172
                     /locus_tag="HIK46_14745"
     CDS             7895..9172
                     /locus_tag="HIK46_14745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QOC01629.1"
                     /translation="MNIRNFNEGSLVGKHNHLEYIVNVDLCHISDIEEIRHDLTKPDNL
                     FFDVKNMNKEGDYFHITYNIDDEYKSFLSAKKESKALKLALMDYVLKVNPLKNNITYLH
                     PANIYFKNIENIKIGFKGHEYLPQPKINALEQYKLLVMSTLSKFTYDKYYRNKFEALSK
                     EKDDFLYRVNNAESFEKLKDIVREELREVQTNHLLNEEKRKKEFRKKYIRNLAIGFIVI
                     LLITSLFAFMITNSKTQKLDQEIANAKNEQQKSKVYENLYNGDVDEAIKGMKQDKNFNK
                     KDLEKTLKKEKKYAQLISLNSKHTPYVIEKLYDNHDESEIRELAFKFENNDTLDLEKKI
                     IDKDGSAFTTGQEGYYKEQNKRLALTSAKEGYIENAEEINKKLKDDDIEKEIEKAKIKE
                     LKDEKDKTKDKDKKKELEKKIDKLEK"
                     /name="hypothetical protein"
     gene            9195..10270
                     /locus_tag="HIK46_14750"
                     /pseudo=""
     CDS             9195..10270
                     /locus_tag="HIK46_14750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000269385.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /name="CHAP domain-containing protein"
     gene            10284..10784
                     /locus_tag="HIK46_14755"
     CDS             10284..10784
                     /locus_tag="HIK46_14755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraH"
                     /protein_id="QOC01630.1"
                     /translation="MKKILLILVAFVVVLTGCNQKESENHKNTEKQATEESEQTGNTKN
                     EMIKGLIEYGYKNDSYKGYEDMKNILSKKMVKQSDVQNQSAKTGNIEKEARDIKLYKDV
                     DDNNNLIYTVKVGITNKKTKKSDYSIRYGKIEMKNEDGKEKIDNITELTKTNIPSMTED
                     VDY"
                     /name="conjugal transfer protein TraH"
     gene            10800..12905
                     /gene="topB"
                     /locus_tag="HIK46_14760"
     CDS             10800..12905
                     /gene="topB"
                     /locus_tag="HIK46_14760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001094110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="QOC01631.1"
                     /translation="MKSLILCEKPSQAMDIANVFEKRTKKNGYIEVVDSDLHINGFLTW
                     GIGHLVELQEPKEYDVRYKNFKEYPIFLERKDFKFKVSEDTKDQYNNIEKIFKNNTIDE
                     VIIATDPAREGENIAYKILNQLEVTDKVVIKRLWLTSKVESSVRKAFKNLLPKEKTIGF
                     YKEGRARELSDWLVGINLTRHFTNVARQFGNEGIIHVGRVSSPTLNMVYVRENNIKNFN
                     SKKYYQVGAKVIKQENVFKTLLKNKFDKEDELHEFLFENDITDLEQTGYVENIEKDKGY
                     SMPPKFYDLSALQEDMNDKYKFSAKQTLKIAQNLYEKKLITYPRTDSRYITDDEKNMLL
                     SNLDYISKNTDMKLNEELTNTALVNPSKIDDHYAILITGNDYKTLNLSNQEEKVYVSIL
                     RNIAKNFMNKEIYETTKIDINVKNLIFILKGKTIIDEGFTALNKNEGINSDQNLPIFQK
                     DEKVKVSLDILSKETTPPKRYTEKTLLKAMANPIETLEDEGLKSTIKEAKGLGTPATRA
                     DIIENLKNNKYIQVQQNKIYITKNGILACKLLEGNLLSKPDLTGQWENYLSSISKGEKD
                     GDSFVSTINKMIEKTIKEEIENSDEIKQLAKEKVKSNNIAKCPVCDKGYLVDRKNFYGC
                     TEHKNGCNFTIPKKMLEKNIPPTVVKMLCEKGETNKLKGFKSKKSGKSFDCKLKLNDNN
                     EIAFNFK"
                     /name="topB"
     gene            12918..13361
                     /locus_tag="HIK46_14765"
     CDS             12918..13361
                     /locus_tag="HIK46_14765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000715270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QOC01632.1"
                     /translation="MKKGIYFLVGVVWSLLIYLVQIIAYALSILSSNQDKQKIFNDPSQ
                     LFLPPATHPLASIIKLVSDKNGIFFILVGVVTLLCIYLLLKQLFEQKDGNENNQDYKIA
                     KHGSHGSARFAKDSELFGEGHYKKLKEKDVVNYVYQSLDENKM"
                     /name="hypothetical protein"
     gene            13379..14995
                     /locus_tag="HIK46_14770"
                     /pseudo=""
     CDS             13379..14995
                     /locus_tag="HIK46_14770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000209435.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA transfer
                     family protein"
                     /name="type IV secretory system conjugative DNA transfer
                     family protein"
     gene            15080..15997
                     /locus_tag="HIK46_14775"
     CDS             15080..15997
                     /locus_tag="HIK46_14775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000383805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QOC01633.1"
                     /translation="MGWIKDAVDKLTDGIAQGMMDFIFNFLYTLFYEPLKFFIWLLDKI
                     LIDPNSITSDYVQNASVLVNSLISSVAVCIFAFKMIQVIKMNTEGNAESPGYYVAQLLP
                     SAMLVGVLPWLVDIMTKISFEATRAFMNVGKTSYLKTIKEWSSLKKGTAGFKEMLGSMG
                     TMAGSQIMFILFILLILIFTIVFIFQFVSRIADLVIMKVVAPLIAVSLLADENNYVSIW
                     WRELLAISLQLPLQVFTFFGGLNLFFGAKLDVGTLLLGIGFFIITVKSPSFIRSMVYST
                     GSGRMATGMAGSSAKLLVRQLLTR"
                     /name="hypothetical protein"
     gene            16015..16392
                     /locus_tag="HIK46_14780"
     CDS             16015..16392
                     /locus_tag="HIK46_14780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000482522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="QOC01634.1"
                     /translation="MLNRVVYCGRIATELNVRKSKNNKSFLFFNLAVPRQNDDKTDFIN
                     CVVFNNKAENLVKYQSKGNLIIIEGSTETYKKDNINMSRCLVDRITYLENKKEDSIQSV
                     IDSEEDKHENYDIISGEDLPF"
                     /name="single-stranded DNA-binding protein"
     gene            16417..16866
                     /locus_tag="HIK46_14785"
     CDS             16417..16866
                     /locus_tag="HIK46_14785"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QOC01635.1"
                     /translation="METILGLIIFGVFGFIIYNSNQKHYRRYQSKINDYIPSLKEDIQV
                     GKINSIATDEQNRDEVVFDWGFSTSVTNKNVMFVESLEEEKIEFQIPNAKSMDKHYKKT
                     FSFVNVTDKDFEKYLYKYVLVLGIKLYITRESYEKLKRNRIITAK"
                     /name="hypothetical protein"
     gene            16994..17203
                     /locus_tag="HIK46_14790"
     CDS             16994..17203
                     /locus_tag="HIK46_14790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QOC01636.1"
                     /translation="MNKNYYFEANGKDYCLSVSKDVFGCSGVAIKENGCYIGMIDCADE
                     EDYLRIENIVKQDIESIINSEIYC"
                     /name="hypothetical protein"
     gene            17306..17518
                     /locus_tag="HIK46_14795"
     CDS             17306..17518
                     /locus_tag="HIK46_14795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QOC01637.1"
                     /translation="MEEKNSMSKKYVSPSHKKRRSVHIYKNVDDLANELKFDLRLNSKQ
                     EVYTKAIENLYKEVHGKSISLDQNE"
                     /name="hypothetical protein"
     gene            17543..18484
                     /locus_tag="HIK46_14800"
     CDS             17543..18484
                     /locus_tag="HIK46_14800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000277143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="QOC01638.1"
                     /translation="MYKKILASGLTVSMLLVGLNNANAEENQITEKTLTEGADLNQQQE
                     KQTRDLFDVNSNVRTYKVDSEDVQHYTGKWYDTIYSSTYIEPKKFRHGVDVEIVTPDNI
                     TDVSKEQYRNAAITAGIQDANIKVGAVVETLGYGALSGIYKAYEKEGSALNEQDIKNAD
                     DEMKELSSISKNNNEEEFSDEALNNSVAEMKQEIAKEKANDNNLSRQDVENIVDDKLKE
                     NGLNKVLSDNQINSIYNIMNNVSNSKVLNQDPKAYEQQAKKLSSDIKDKAGGLIEKAKG
                     LNTEENRNILQKIWDAIVDFVNWLVNLIKSLF"
                     /name="DUF1002 domain-containing protein"
     gene            18629..18781
                     /locus_tag="HIK46_14805"
     CDS             18629..18781
                     /locus_tag="HIK46_14805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QOC01639.1"
                     /translation="MNKETLVSLIDVMIGLTDSEKQKLLKMDKRKVEFRYKMALTEKTD
                     ELFAE"
                     /name="hypothetical protein"
     gene            18799..19527
                     /locus_tag="HIK46_14810"
     CDS             18799..19527
                     /locus_tag="HIK46_14810"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QOC01640.1"
                     /translation="MDKKQATQIIQNLVIIHRNIHWGSIKSSPTSSWDRYSINYSKEEF
                     IFYYQAFSEYACDLDNYMTSAMGEGVPESDLPEFESNVRIAIERMIEYIEGYNINLYAK
                     ENFIERSGISDVFKILDIDLDSILKRINDNHTSLIKECKNNYLSFYDQKINCTLSSINN
                     DINSNKKFNKHLFIRLEAMKNLKKLAEKDRKIEDVTHKIDTAIFDKLVPESIYHLALTK
                     EIELLKKDKKKEKVRKIFKI"
                     /name="hypothetical protein"
     gene            19564..20019
                     /locus_tag="HIK46_14815"
     CDS             19564..20019
                     /locus_tag="HIK46_14815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001632017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="QOC01641.1"
                     /translation="MKKVYIDNIKDYIIIDDEDYNSINKYKWHINDYYGTTRALAFING
                     KKVALPYFITGVVNAYQKNKNLDFRKQNIGIDQHKHRYRKPQRNASSKYKGVRRAKLRS
                     NIRYISSIKLEDKSKHLGCFISEKEAARAYNEAVVEYWGGNGYLNDI"
                     /name="AP2 domain-containing protein"
     gene            20067..20288
                     /locus_tag="HIK46_14820"
     CDS             20067..20288
                     /locus_tag="HIK46_14820"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QOC01642.1"
                     /translation="MKSNNNLIINIIGVVATYFYIIAFNIVILWFLLYLFHNHFKGIEM
                     FFSILLTVITLIVAIGMNKIFYRINMKH"
                     /name="hypothetical protein"
     gene            20592..21149
                     /locus_tag="HIK46_14825"
     CDS             20592..21149
                     /locus_tag="HIK46_14825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002487748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="QOC01643.1"
                     /translation="MANIGYARVSTKDQSLDSQIDILKEYGCTKIFSEKISGRKYQRNE
                     LDKCLEYLRSGDTLVIYKLDRLGRTVKQLVELAQWFEENGIELEIISMNINTKDPMGRM
                     FFTISSAYAELEADLLSQRTKAGLESARARGRLGGRPPIPEHKRREVCYLYNEQKMTVS
                     DISKNTMVSKASIYRIVRENKH"
                     /name="recombinase family protein"
     gene            21428..22201
                     /locus_tag="HIK46_14830"
     CDS             21428..22201
                     /locus_tag="HIK46_14830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QOC01644.1"
                     /translation="MEVIRLNQQLFNSNKFNKNEIEDNKNGKRPYFYSFKRNNHRICIP
                     LRTNTRSVPERYKLKLNQVQPHKPNSALDTTKSLVIDENTYKANKQKTSLHSSVYNYIK
                     NNRDSLENKFDVLTKDYVNAKGKMADIPLTKYSTLQYFHDELNLQPIIDNKLLKNCVKE
                     LNDNGYTNKYENLKTEIPNLSETIESYEILNEFKKLSNYPSKLVNDDIKNPVLEIVKDN
                     NKFSLTSNNITENPEKHMKNFLDYDPKDRENNLDL"
                     /name="hypothetical protein"
     gene            22274..23902
                     /locus_tag="HIK46_14835"
     CDS             22274..23902
                     /locus_tag="HIK46_14835"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QOC01645.1"
                     /translation="MAFEERYFFETNMDLDITSIQLGSSITYAPAPKNQQDLTNRNIVG
                     NLIFKHNYYNDVLSMPIYEKENNNYKIPIVYEKEGRFSKNDNDNFYIDNADFYFTLNTA
                     HKGYEKLVNAIENNEKVEFSQNQNQLDDFSQLGEYSNYSYDNLYNSLVKNINYYNEVFS
                     QYREPEINDIEKMTVNNFDYEVKFNPETQHIYINNIPTHSVNEQHEIRVLNDNLSKNIE
                     KDYFNKDYKFSYNDYKTLEDNSYTYIDLNEYTDSNNKFIKNLIEDVPPNELLVDSIKQR
                     INYVDQQINFRDINVLKNDLNNFAEINNLTDLDEVNYLNNSYDDYLNIISTNIENDIEK
                     DGLKNRFMYLDEPFHLMKTTTYTLYDNIENDIRNISALDRNKRSDLREVLTYLHDSKNN
                     IGNLISKHETSKSSMISQNSLSILDNEKFKLTNQDFHTQKEQIKAESFYEGMKASTLPI
                     NQITPQEYKNRENDIEIISEFIKYAKSEVNNIDLKPDFINNKLHSNNNSIDFDSILIGS
                     EEQHDVFLENLKEESLKTKEKSLDI"
                     /name="hypothetical protein"
     gene            23913..24092
                     /locus_tag="HIK46_14840"
     CDS             23913..24092
                     /locus_tag="HIK46_14840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000921495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QOC01646.1"
                     /translation="MLKTYTEILGSELPIYTSKPNDDIYVFNDEKKENCEYELIGYYLY
                     DTENDLYKDLFILV"
                     /name="hypothetical protein"
     gene            24108..25826
                     /locus_tag="HIK46_14845"
     CDS             24108..25826
                     /locus_tag="HIK46_14845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LtrC"
                     /protein_id="QOC01647.1"
                     /translation="MAYSKENFKKKKIDSIVENLNKKLDDFRNNDDMYKEFLDTTSKFH
                     NYSINNILLIADQKSDATAVAGYKAWKNKFDRQVQKGAKGINIIAPIIKKREVEMKDEN
                     GNVIRDINGNPKTERKPAITGYRAHNVFDISDTKGKPLITAKDLIKTEFENSNDYKDLY
                     NEFKDYLNKELRVSVEERMFMEDSNLGENTKGYYSPNNDEIIIADDNSYDLKFKTLIHE
                     YAHSQLHGDQEIFNESTEKQRALRELEAESSAYIVANYYGLDTSDYSLGYISGWAKDLD
                     DDTIKNHIKNVHSFAQTTIEEINNLPQFSQYIDKKLESEFNKDMYNDLNKMIDTNLKNG
                     FDKVTIIEGNLENKFDMKKVTDNTFENDKFKVTLDYKGFNINNLQDNCKIKLENKLDNT
                     LNKNFDYTQTYSKNLINNTSTIYVTDNNMEENKVYRHNRDIEGNVLKEKSEQSPSSELI
                     TFEKFVNKSVEEKGILNTMTHLVQNGFNMGYEMNINENDNTDETYINMSKVEKNGFKST
                     LTSKIEHDQSNNVYVDFKMKNSSGIKNLSFKETQNEFETNKDKPLKLESKQNIDL"
                     /name="LtrC"
     gene            complement(25863..27860)
                     /locus_tag="HIK46_14850"
     CDS             complement(25863..27860)
                     /locus_tag="HIK46_14850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001585982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="QOC01648.1"
                     /translation="MAIYHFQNKIVSRGKNQSATSKSAYNSASKIYDYKEKDYKDYSNK
                     QCDYSEILLPKNAGVEYSDREFLWNKVHDVENRKDSQLAREIIIGLPTELNEENNVKLA
                     KDFSESLADEGMIVDLNIHKISSDNPHAHLLCTLRGIDENNEFEPKRKGNKFIRDWNTE
                     EKNLEWRKRWETIQNKHLKMRGFNVTVSSETYKNQNIDLEPTLKEGWKARKFEDETGIQ
                     SEVSKYNEEIKKRNQSKINNLYKDINDLKSNKLNSFSYMNNNDTKLLKNMAKDLKLFIT
                     PINMFKEKERLYDLKEKTSLISDDDTRLRKVDDIEDRETKLEKVREIFDKQSELFFNKN
                     YPKEENNFTSDEKTFITRYILNDCDQLPASTELDRIVEDKRQKEAEISLNTILGNRDIS
                     LQSIKEESNFFEGKLNNLLEKNNLSFEDIENDSYHSTNDQSKIDYYISKLERIAKAENI
                     LDDYYNFQIKDLFSDSDEYSAFNEVSSIEEKQQLIDFKSYHGVDNTLRMLDERKFIPKY
                     NNEDRTFILDKLLTLQEKEFKPNKSQYDEYVIGAVQKTLLNDFDFDCKNNNDIKHLFQE
                     TNLTNDNDNKRKIEEFYESNDVVIDKEQYNNYYASSKGYGLINASFDNFIFNFNELFRE
                     RLPKYINHQYKGKNHSKKRHEVRNKRGIHL"
                     /name="MobA/MobL family protein"
     gene            28062..28331
                     /locus_tag="HIK46_14855"
     CDS             28062..28331
                     /locus_tag="HIK46_14855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QOC01649.1"
                     /translation="MSNIDKMIEQKKKLQEKIKKEKEKEYVKFGRWFFNKLNINSSAEA
                     KKIINKDLLYKDINSNDKNEHDSNVLYEESESVKYDKFNENTSE"
                     /name="hypothetical protein"
     Typing          5866..7874
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="88.06"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          13380..14809
                     /name="MPF_T"
                     /typing="mate-pair-formation"
                     /tool="MOB-suite"
                     /identity="87.056"
                     /coverage="87.0"
                     /evalue="0.0"
ORIGIN
        1 tgagtgaaat ttatgttatg gctttagact ttggaaatgg atttgtaaaa ggaaagatta
       61 atgatgaaac ttttgtagtg aaatctcgta ttggaaagaa aacaaactct gatagtcaat
      121 taaaagggtt tgttgaaaat aaactagatg ttagtgagtt tattattaat ggcaataatg
      181 atgaaatact attatttgga aaagacttag acaaagtaac aaacaatggt aaagatacag
      241 cttcaacaaa tgacagatac aattatcagt catttaaaga cttagtagaa tgttctatag
      301 gcctactagc aagagaagtg ccagacgagg ttgtaaacgt tgttatagca actggtatgc
      361 cttctaatga gattggaact gaaaagcaaa agaagtttga aaaaatactt aataaaaatc
      421 gactaataga agtagacggt atttcaaaaa ctatcaacgt aaaaggtatt aaagttattg
      481 ctcaacctat gggaacatta cttgatttgc acatggataa tggtaaagtt ttcaaaagat
      541 ttacagaagg taaatatagc gtgttagatt tcggaagtgg tacaacaatc attgatactt
      601 atcaaaatat gaaacgagta ggagaagaaa gctttgttat aaacaaagga atgattgatt
      661 tttataaaag aatagctact cacgttcaaa gaaaagcagg tggaacacct gtaacgccta
      721 gacaaataga agaaggacta gaattaatgc aatgtaaggt ttctgcaaga gaaactattg
      781 atttcagaga agatttctac aatgaacaag acaacgtaac tcaagaagtt ttaagtaagt
      841 ttgaaaccgt agtcggcaac ttcaattcaa ttgatcgtat tgttgttact ggtggagggg
      901 ctaacattta ttttgatgtt ttaagtcact attacccaaa tgtctttgaa aaaaccgaag
      961 aaagccagtt aagtaacgta agaggttatg aaaaattggg ggatttacta agacaaaaag
     1021 ttgaaaacga aggtaaatag tcatgaaaaa aaaagaaacg caacatcttc taaaaataaa
     1081 aaaagaagat taccctcaaa tcttcgattt tttagaaggg cttcctagag gaacgaaaac
     1141 agcgcatatt agagaggcgc tgttgagata tattgctgat gaaggagaaa accctagaat
     1201 acctactaaa agccgtaaaa atagcgttta tgtacgttca gagcaaaatg atgactacaa
     1261 cgttactagt aaaacaaaag aaagctatca tgattatatg aaacgacagc aattaactaa
     1321 tataagcgat tcaataaatg atacagattc caataaaaaa gatgaagaat ttgtaaatat
     1381 aaatattgat gatttataaa tttacatttc ttcatctaat tctagtttgt actttgcatt
     1441 tctaactact ttttcaaaag gtataccgta ataatctgat aacaacaaca gggtatatag
     1501 cgacaatttt tttattttgc cattttctat tcttgataaa taaccagctg acatattgag
     1561 atcaaacgct acttcttctt gtcttttatt caacatttgt cgctggtttt taatctctaa
     1621 acatatgtat ctatataatt gattaacgtc gtagtcgttc atatttattt gcctcttaaa
     1681 tcctttttat tcaattatat tagtaaacta gttttaaata catttcacta aagtaaaaag
     1741 ttgccttata agttaagttt gtattttgaa tgtaagcgaa acagtgttat attaaatata
     1801 gaaaaagaca cctaacagca ttagcccgcg ttagatgtct aaaggtttaa ataatctatt
     1861 tttgtgattt atttacttct gttaattatg attatatatg ttttgtatgg tttttacaag
     1921 cttaatgctt acaaatacca ttaaactaaa tggaatttat aaatcagatt atacaaaaat
     1981 tattttattt aaacctctta ttctacaaat acagaaaaga ggtttttatt atgtctacta
     2041 aattttatat acaagaaaat tttagagaac gattttatca attaccaaaa gtttttttta
     2101 caaatcctaa ttaccaaaaa ctatctaatg acgcaaaaat agcgtacgct attcttcgtg
     2161 atcgtctcga gttatcaatt aaaaataact ggattgatga ggagaacgca atctttttca
     2221 tttacacaaa cgaaaatcta atgtctatct taaatttagg aaaaaataaa gtgataaatg
     2281 taaaaaaaga attagaagaa gttaatttat tggagcaaaa aaggcaaggt ttaaataaac
     2341 ctaacaaatt atatcttatg aagcctatca ttactgaaaa agatatttac acaattaaaa
     2401 atgaagaaac tgccaatgaa accagtaatg acagggaagt ttataattca aacttccaaa
     2461 ggtttgcaaa acaaacttca agaagttgct caaataaacc tcaagaagtt gctcaaataa
     2521 actctagtga tactgatatt agtgatactg atattagtga tactgatatt agtgatatga
     2581 attatatgca tgataactac gatactgaag tgaataatta taattcacat tcaaatcatt
     2641 caaataactt tcatcaaaaa caattcgata ttgattctgt taaagaatta gaattacaag
     2701 agtttccaga atacctaaaa tcttacttat tgaattttga tttagatgat ttaaaacata
     2761 ttaaaaacat aattcttaaa gctaaaaaat cgtttaataa tagagtaggg caagaagggt
     2821 atcactatat gctagaagat attgaagctg aactagtctc agttcttaaa agacttaaag
     2881 ggtacatggt tagaaaaaac gaaaaagtag aagacatgca aagttacttg atgagaagca
     2941 ttattaacga aattgaagat taccattcat tgaatttaag aagagaagct tttaatcatt
     3001 tttaaaaaca aattactaat aaaaaaataa aggattttac attttgtttt gtaaaatcct
     3061 ttataataaa tatttgagcg aggtggtaaa catgtaaatt aaatattttc tttttcgaca
     3121 acctctaacc ctttttttag tatatatctt ccagcttgag aaatattatc aaattcgcct
     3181 ttattagcaa tttgtgcaat acgtttcttt atatctggat caactaataa atgtaatgag
     3241 gttttattca ctttagattg attgtagttt aacgtcattt tcacatctcc tttttaaagg
     3301 ttttactata ttataacatg acatgacatg aaaaaaacta gtaaattttt ctacaatcac
     3361 atgacatgac atgacatgtt gtgatataat agacgtatca aataagaaag gtgggttgtc
     3421 attggataat gtagctatga gatataggat tgagaagtac cgaaaaaaag aagagtattc
     3481 taaaaaaaat caacaaaact acaaaacaaa ctttgggata aaagacaatg aaactagtac
     3541 ttttaatgtc aaaggtatag ctacagatag aaaagagaac aaactgattt tggcagaaga
     3601 caaacaagac aaccaaaaac tactaatgta tgccaataaa aataatgatt tatattattt
     3661 aaattctgga agtagttata aggaagctgt tcaaaataca ttcggaaaaa aagtgaatta
     3721 tgaggttatt gaagacgaat tatttattta caactcaaaa aacaaatcat taaataatta
     3781 tgaacagcta aataattatc atcttaacga caaacaaatt gaatatgata aacctttaga
     3841 agaagaaagg aagcgaagac ttactgacga acataaaatt tcaagccaag ctaaagaaga
     3901 tttagcaatt agtttaggcc tttcagcaac ggcttttaaa aatgatagta atataactga
     3961 cattgaaaaa gttactgata acgaaagtat gataacgatt gaaaatgaaa taaatggtaa
     4021 gacagaacat ttaatttcta attttaaaga tgactttgtt agtaatgtta aagaaaaatt
     4081 gaatgtatct ccgtcagtaa gattaggatt tgaggaattg aaaaacgcct caatgcaaat
     4141 agcaatgggc tttacagagt tttatggagc aagatatgac gaaagtacat tagaacgaga
     4201 cccaaaagtt gtacttacag aaaagggata ttctttatct acatttgata aaaatggtaa
     4261 taaaaaagaa attaccactg ctgatacttt tgaagaagca gtaaaactat caaaggaaat
     4321 gaaaaacgat aattcaatag aacttaaatc taacgaatta gaacaagagt tacaaagaaa
     4381 taagggatag aaaaggagat tataaaatgt ttaaaaaatt tagtatatca gctttatata
     4441 ttacatttct tagttacgtt ttaacatctg atgtattggg agcaaatcca ggagcaaaaa
     4501 ttgaacaggg attacaaaaa gtccaaacct tcttaacagg aattattgtt gctgttggta
     4561 tctgtgctgg tgtttggatt gtaataaaaa aattacctgg tatcgatgat ccaatggtaa
     4621 aaaacgaaat gtttagaggt gtgggaatgg tcttagcagg tgtaggagtt ggcgcagctt
     4681 tggtatggct cgttccttgg gtttacaact tattccaata aaaactaaag ctacatttta
     4741 acaatgtagc tttaatttta actaatagga ggttaaaaca tggctaccga gcaagatgtg
     4801 aaagatgtac tactggatat gctaggggaa gaaaaaaaag ttaaaacaaa taaaattcct
     4861 cgaaatgtag acgcaagcta caaagttgct ttaggactta accttaaaga acttgcaatt
     4921 tcagtaatac caccagtgat ttttatggct attggattta ttgcaatagc tcttatgaat
     4981 ttgcttacta tatttatggg atttacagtt tttataactg gattagtaat atttttaact
     5041 atttatgctt tattagctat gagacctata ccgtctaaag aaaatattag aatgatagat
     5101 cacgttaaac aacaacaaaa ttttactaaa agacaaaaag tatttttcta tggaagaaaa
     5161 gaagaaggtg tagacgatgt ttaagaaaaa gaaaaaacaa cgaaacgagc aaagtttcga
     5221 aattattaat cgttatataa aaggagacgg aaaaaatcaa actatacaag aagattctct
     5281 aatagctgga ttctataaag actacgtagt tactaaagat ggttatatta gtggaggtct
     5341 taatataagt ggtgtgaata cagaacttct aactaagttt gaacaaaacg atttattaga
     5401 agaatattct tcatatatat ctaacagtat ctatgatgag cctatgttta aaactatcac
     5461 tgaaccagtt aacattcaaa actatattaa attgctttat agagaagtta ttttagatat
     5521 gaaagaacat gataataaac cgagtaggag agggcaatta atagctagta gaattttgtt
     5581 cttacaagaa aaactatcga aaggagaaat gagtactaaa aaacattatg tttttatgaa
     5641 agaaaaaatt actgaaaata cagtagctca actagatcat gcagtaaaca gacttcatga
     5701 aaagttaaat ataaataaag aagcaataaa acaagccttt tctcattacg gtttggaagt
     5761 gagacctata tatcaacaag aatatttaaa tcagttttac gctttgtatg attataaatc
     5821 ttataatgaa taccatttaa gtaactaagg gaggaattac ttttatgcta ggatttacta
     5881 acaaaaagca gaaacaagaa aaaagcaaag ttaataatga ggcttttgaa aagttaacag
     5941 aagtattgga tacagattca atagatagta tttatccttt cagttggata gaaaaaaaat
     6001 cacacatcga aacaggagag aacttcttta aaaatttatt agtggtagac tatcccgatt
     6061 cagccaaagg aacatattta tctaatctgt taaagaaaaa tggaaatgta gaaattacac
     6121 aatttattag accagcgaat attgatagaa tgatagatca tttgaacaac tctatcaaaa
     6181 ataaaagagc agaacgatta agaactacag accctaaaag aaacgctact attaaaagag
     6241 aaattgatag tagtgaaaaa caacttgata agtttttaga tgaaaaaaca aacttcatgt
     6301 atatgtatat ttatattact ttgaaagcag attcatatga aaaaattcaa gcattagaga
     6361 aagatataaa acgtacgctt acgagattaa gacttaaaac acatacaccg acaaacgcta
     6421 tgcgtgaaag ttttcatact gttttaccaa taaacagaaa ctttttagca cccttcacac
     6481 aacaaaatat ggatactgca acagctgggc atttctttat gtttgatgat tcagaaatca
     6541 ttgatttaag tccaaataca tcagtttttg ggattaataa aaacacagat tctttagtag
     6601 ctgtggactt taacaacaaa gaaaaaactc taaataaaaa tatgactatc atcggaacga
     6661 gtggcgtagg taaatccact ttaaacatga gaattatatt agataacatc aaaaaaaaga
     6721 taagacaatt tataattgat ccagaagatg agttttcggc aataactaaa tattatggtg
     6781 gtacagttgt taatatttca actagctcaa acattaaaat taatccattt gaaatttttt
     6841 cggaagaagt atttgaaaaa gaagatgaat cagataatga aactaaatca gatgttttaa
     6901 ctgattcatc agaagaagaa aactacattg atacaatagt tcgttctaaa attggtaaat
     6961 taaaaacttt ctttagagtt ctaaaagatg aaattagtca aacagaaata tcggtattat
     7021 cttcaacttt aagaaagttg tatcaaaaga aaggttttac aggtaacgca aaactatcgg
     7081 attttactag taaagattat ccaacactaa ctgaattata caatgaatta aaaaatttag
     7141 acaaagaaaa atatgaaatt ctaaaagatt taactttgat tatagaagat tacacaattg
     7201 aacatggtac aacaacgatt tttgacggtt atacaaatat caaacttgat aatgatatta
     7261 ttacttttaa tttaaaacct ttacagactg aaaaagatgt acaaagtgca gcgtatttaa
     7321 atatatttag ttttttatgg gacgaaatca ctaaagatag aactacagaa actgtactta
     7381 tgacagatga acttcacttt ttagctacaa atgagtatag tttggacttt tattatcaag
     7441 catataaacg aattagaaaa tattctgggg gagctatcgc ctcaacgcaa caaataaaag
     7501 atattttaag aacatctaga gaaattggtt cggctattat tgaaaatagt cacactaaat
     7561 ttttctttgg aatggataat gtaggagtag aagatgtggt tgataaatta ggtttgaaat
     7621 ttagtaaaca agaaatatca catcttacta aaaagaaaaa aggagaggct ttattactat
     7681 atggaactca aagagcattt ataaaaatag aactagacaa agaagaaata agattgtgga
     7741 ataacgactt atatgaaaaa acttacaatg aatcggcaag tattgaacca aattacgttg
     7801 aacaattagg attgtcggat attgacttag cagaattaga agaagaatta cgacaatatg
     7861 aaatgattta tgagtaataa agggaggtcg aattatgaac ataagaaatt tcaatgaggg
     7921 gtcattagtt ggtaaacata atcatttaga atatatagtc aatgttgatt tatgtcacat
     7981 ttcagatata gaagaaatac gccatgattt aacaaagcct gacaatctct tttttgatgt
     8041 aaaaaacatg aataaggaag gagattattt tcacatcaca tataatattg atgatgaata
     8101 taaatccttc ctttcagcca aaaaagaaag taaagcttta aaacttgcat taatggacta
     8161 tgtactaaaa gttaatccat taaagaacaa tatcacatat ctacacccag caaacatata
     8221 ttttaaaaat attgaaaata taaaaatagg atttaaagga catgaatatt taccgcaacc
     8281 taaaatcaac gctttagaac agtataaact acttgttatg agtactttat ctaaatttac
     8341 ctatgataaa tattatcgta ataaatttga agcattgtct aaagaaaaag atgactttct
     8401 ttatagagtg aacaatgccg aaagttttga aaagttgaaa gatattgtta gagaagaatt
     8461 aagagaagtt caaacaaatc atttattgaa cgaagaaaaa agaaagaaag aatttagaaa
     8521 aaaatacatt cgtaatttag caattggatt tattgtaatt cttttaatta cttctttatt
     8581 tgcttttatg ataacaaatt ctaaaacaca aaaactcgat caagaaatag ccaatgctaa
     8641 aaatgaacaa caaaaaagta aggtttatga aaatctttat aatggagatg ttgatgaagc
     8701 aattaaagga atgaaacaag ataagaattt taataagaaa gatttagaaa aaacattgaa
     8761 gaaagagaag aaatacgctc aactcatttc tttaaatagc aaacatacac cttatgtcat
     8821 tgaaaaacta tatgacaatc atgatgaaag tgagataaga gaattagctt ttaaatttga
     8881 aaataacgat accttagatt tagagaaaaa aataattgat aaagacggat cagcatttac
     8941 gacaggacaa gaaggatatt ataaagaaca aaataaaaga ttggctttaa catctgctaa
     9001 ggaaggctat attgaaaacg ccgaagaaat caataaaaaa ctgaaagacg atgatattga
     9061 aaaagaaata gaaaaagcga aaatcaaaga gttaaaagac gaaaaagata agacaaaaga
     9121 taaagataag aaaaaggaac tagaaaagaa aatagataaa ctagaaaaat aaccaaagaa
     9181 ggagaggatt ttaaatgtgg agtgctattg ctaaaggtat agttatggct ttcaaatcta
     9241 gacaatataa aaaattaata aagcctgcaa tagttattgt cgtaggtttt ttccttatga
     9301 ttttccttat ggttactttt cttgtaggtt cttttactaa ggaattaaat tcaagtgggg
     9361 agcaagcgat gaaagatgct gaaaacactt ctactggagc ttgctctggt ggaagtgtag
     9421 ataaatcagg tatttccacc tttgagcgta acgctaaagg tggtgctcta gaaggtaaag
     9481 cagataaaat gattaaaata gctaaaaaaa ataaaatacc tccaaaatta tttatggcaa
     9541 ttgtagcttc tgaatcgcaa tggggaaagg agcaaatgct acaagacaaa aaaaccctct
     9601 aagtattatg ggagcaggac ctttaaaaca ttattctaac attgaagacg gattagacgc
     9661 tggagcaaaa aatttatatg acttatatat ttcagaggga ttgaacacac ctaagaaaat
     9721 cgggccgaaa tatgcccctg taggagcgtc taacgaccct acaaatttga ataagaactg
     9781 ggttccaaca gtaactaaaa taatggattc tttcggaggg aaagacgcta aatgttcaac
     9841 ttccggtgga tcagacggag gagattttga tttaagtgga agcaagttcc ctaaaatcaa
     9901 aggttcgaaa gaatataatt tcaatcccac atatccatgg gggcaatgta catggtatgt
     9961 acatcaacgt aggcatcaaa taggaaaaga tgttcctaca actctaggta atggtggaga
    10021 ctgggcagaa aatgctaaaa atgaaggttt ttctacagga aaaaaaccaa aagagggagc
    10081 ttgtgcctct attaagccag gtgttttagg tgctggtgca ccatacggac atattatgtt
    10141 tgttgaaaaa gtcaaaaagg acgggggaat tatagtttca gaatcaaatg ttaaagggtt
    10201 aggagttatt agtaaaagag aattttctaa gtcagaagca caacaaataa cattcatata
    10261 tgataaatag gaggcgcttt caaatgaaaa aaatattatt aatattagtt gcttttgtag
    10321 tagttctaac agggtgtaat caaaaagaat ctgaaaatca taaaaataca gaaaaacaag
    10381 caacagaaga aagtgaacag acaggtaata ccaaaaatga aatgattaaa ggtttaattg
    10441 aatatggata taaaaatgat agctataaag gttatgaaga tatgaaaaac attttatcga
    10501 aaaaaatggt taagcaatca gatgtccaaa atcaatctgc gaaaactgga aatattgaaa
    10561 aagaagcaag agatattaaa ctctataaag atgtagatga taataacaat ttaatttata
    10621 cagttaaagt aggaattacg aataaaaaaa ccaaaaaatc tgattactca attagatatg
    10681 gaaaaattga aatgaagaat gaagacggaa aagaaaaaat agataatatt acagaattaa
    10741 ctaaaaccaa tatacctagc atgactgaag atgtagatta ctaataagaa ggtgtaatta
    10801 tgaaatctct aatattatgc gaaaaaccct cacaagcgat ggatattgca aacgtatttg
    10861 aaaaaagaac taaaaaaaat ggttatattg aagttgttga tagtgacctg catataaatg
    10921 gatttcttac ttgggggata ggtcatttag tagaattaca ggagcctaaa gagtatgacg
    10981 ttagatataa aaattttaaa gaatacccta tttttctaga aagaaaagat tttaagttta
    11041 aagtttccga agataccaaa gaccagtata acaatattga aaaaattttt aaaaacaata
    11101 ctatagacga agttattata gcaactgatc cagctagaga aggcgaaaat attgcttata
    11161 aaatattaaa tcaattagaa gttactgata aagtagttat taaacgtctt tggttaacat
    11221 caaaagttga atctagtgtt agaaaagcat ttaaaaattt attgccaaaa gaaaagacaa
    11281 taggttttta taaagaaggt agagcaagag aattgagtga ttggttagtg ggtataaatt
    11341 tgactagaca ttttacaaat gtagcgcgtc aatttggaaa tgaaggaatc attcatgtag
    11401 ggagagtatc aagtccaacc ttaaacatgg tttatgtaag ggaaaataat ataaaaaact
    11461 ttaattcaaa aaagtattat caagttggtg caaaagttat aaaacaagaa aatgttttta
    11521 aaacgctatt aaaaaacaag tttgataaag aagatgaatt gcatgaattt ttatttgaaa
    11581 atgacattac tgatttagaa caaactggtt acgttgaaaa tattgaaaag gataaaggct
    11641 attctatgcc tcctaaattt tatgatttat cagcgttgca agaagatatg aatgataaat
    11701 ataaattcag tgcaaagcaa actttaaaaa tagcacaaaa cttatatgaa aaaaagttaa
    11761 taacatatcc tagaactgat tcaagataca ttacagacga tgaaaagaac atgcttttat
    11821 ctaatttaga ttatatttct aaaaatactg acatgaaatt gaatgaagag ttaaccaaca
    11881 cagcgttggt taacccttct aaaattgatg atcactacgc tattttaatt accggtaatg
    11941 actataaaac attaaattta agcaatcaag aggaaaaagt atatgttagt atacttcgaa
    12001 atattgctaa gaatttcatg aacaaagaaa tttatgaaac tactaaaata gatattaatg
    12061 ttaaaaacct tatttttata ttaaaaggta aaactataat agacgaaggt tttacagctt
    12121 taaataaaaa tgaaggaatt aattctgatc aaaacttacc tatatttcaa aaagacgaaa
    12181 aggtaaaagt ttctttggat attctttcta aagaaacaac accaccaaaa agatatacag
    12241 agaaaacatt gttaaaagca atggctaatc ctatagaaac acttgaagat gaaggtttga
    12301 aatctaccat taaagaggct aagggattag ggacaccagc aacgagggct gacattatag
    12361 aaaatctaaa aaataataaa tatatacaag ttcaacaaaa taaaatatat attactaaga
    12421 atggtatttt agcttgtaaa ttattagaag gtaatttgtt gtctaaacca gacttaacag
    12481 gacaatggga aaactattta tccagtataa gtaaaggaga aaaagacgga gattcatttg
    12541 tttcaactat taataaaatg atagaaaaaa caattaaaga agaaatcgaa aatagtgatg
    12601 aaattaaaca gttggcaaaa gaaaaagtga aaagtaataa tattgcaaaa tgcccagtct
    12661 gtgacaaagg ctatttagta gatagaaaaa atttttatgg ttgtactgaa cataaaaatg
    12721 gttgcaattt tactatacct aagaaaatgc ttgaaaagaa tatacctcca actgtagtga
    12781 aaatgctatg tgaaaaagga gagacaaata agttaaaggg atttaagtct aaaaaaagtg
    12841 gcaagtcttt tgattgtaaa ttaaaactta atgacaataa tgaaatagca tttaatttta
    12901 aataggggga gaaacatatg aaaaaaggaa tatatttttt ggttggtgta gtgtggagcc
    12961 ttcttatata tttagttcaa ataatagctt atgctttgag tattttaagt agtaatcaag
    13021 ataagcaaaa aatctttaat gatccttcac agttattttt accaccagca acgcacccct
    13081 tagcatcaat tattaagtta gtttctgata aaaacggaat attttttatt ctagttggag
    13141 tagttacact tctttgtata tatcttttgt taaagcagtt gttcgaacaa aaagacggta
    13201 acgaaaacaa tcaagattat aaaatagcta aacatggatc tcatgggtca gcaagatttg
    13261 ctaaggatag tgaacttttt ggcgaaggac attataaaaa attaaaagaa aaagatgttg
    13321 taaattatgt ataccaaagt ttagatgaaa ataaaatgtg agaaaaggaa gggatataat
    13381 gactacaata ttaggagaat tggatactaa aaacataagt caaaagcagt tagttattca
    13441 agattttgat actaaatgtc ctaatagaaa tatatttgta gtaggagggc ctggttcatt
    13501 taaatcagca ggctatgtaa tccctaatgt aataattaaa aatcaacagt ctatagttgt
    13561 tacagacccc tctggtgaat tatatgaaaa aacagctaat attaagagaa tgcaggggta
    13621 cgatgttagg gtagtgaatt tcaagaactt tctagcgtca gatagacaaa acttttttga
    13681 ttatattgat aaagattctg atgcatctat tgttgcagaa ttaattataa aatcagcagg
    13741 cgattcaaaa ataaataaag atgtatggtt taaatcatca gtcggattat taaattcatt
    13801 gatattatac gctaaatatg aatttgagcc agaaaaaaga aacatgggaa accttattaa
    13861 atttgttcaa aataataaac ctaaaaaaga ttcagatgaa ggatcggcag agctagacaa
    13921 aaggtttgct gaactcccta aagaccaccc agcaagagaa agctacgaat ttggatttga
    13981 tgtatcagaa gacagaacac gttcaagtat tgtattaacg tttgtttcag atttaagaaa
    14041 ctatgtagat aaagaagtta gaagttatac aagtgattcg gattttgatt taaaagacgt
    14101 tggcaaacga aaaactatag tatatgttat gttgccggtt ttagggaatt ctaatcaatc
    14161 cttatcaagt cttttctttt cacaaatgtt tcagcaactc tatagattgg gtgatgataa
    14221 tggcgctaaa ctaccttatc ctgttgattt tcttttagat gagtggccga atattggtgc
    14281 tattccagac tatgaagaaa cattagctac ttgcagaaaa tatggaatag gtatatctac
    14341 aattgtacaa tctatttctc aagtggtaga taaatataat aaggataaag ctaatgcaat
    14401 aataggaaat catgcagtaa ttttatgttt gggaaatgtt aataatgata cagcgaaata
    14461 tattaaagaa gaattaggta atactactgt agaatttgaa actagtagtg aaggttcatc
    14521 aagtggaaaa gatagtagaa gtaaatcatc taataaaaac gtaagtttta ctggtagagc
    14581 tttattaaat gaagatgaaa ttagtaatat ggaacaagat aaagcagttt taatcactaa
    14641 gaatagaaac cctaaaataa taaaaaaatg tgcatatttc aaaatgtttc ctaacttaac
    14701 agaaaaatat acagcaccac aaaatgaata taaaagagtt aagaatcaaa gcatgataga
    14761 gcgtcataaa aaaatacaag aagagtggga taaaagacaa gaggaaataa aaagaagaaa
    14821 aattgaggag tataaagaac aacaaaaaca attagaaaaa gaaaaaaaat gaagaaatga
    14881 agaaaagaat agtcaattag aaaagccgga acaacaagaa caagagaaaa aaacaatgag
    14941 tgatacgaaa aaatcatttt atgataaatt aaaacaaaaa caaaaacaaa gttaaaaaaa
    15001 taaaacactt ttaccataac atgacatgac atgttatggt aaaagtgtta taattattgt
    15061 tgaaagacga ggtgttgaca tgggttggat aaaagatgca gtagataaac taactgacgg
    15121 aatagcacaa ggaatgatgg actttatttt taattttttg tatacattat tctatgagcc
    15181 tttaaaattt ttcatatggt tactagataa aatattaatt gaccctaata gtattacaag
    15241 tgattatgtt caaaatgcct ctgtattagt taacagttta attagttcgg ttgcagtttg
    15301 tatatttgct tttaaaatga tacaagtaat taagatgaat acggaaggca acgcagagag
    15361 tccaggatat tatgttgctc aattattacc aagtgccatg ttagtaggag tactaccatg
    15421 gttagttgat attatgacaa aaatttcatt tgaagcaact agggcattta tgaatgtagg
    15481 taaaacaagt tatttaaaaa ctattaaaga gtggagttct ttaaaaaaag gaactgctgg
    15541 atttaaagaa atgttaggat caatgggaac aatggcaggc tctcaaataa tgttcatact
    15601 atttatttta ctaattttga tttttacgat tgtatttatt ttccaatttg taagtagaat
    15661 tgcagattta gttattatga aagtagttgc tccgttaatt gcagtatctt tattagcaga
    15721 tgaaaataat tacgtttcta tttggtggag agaattactt gcaataagct tacaattacc
    15781 tttacaagtg tttaccttct ttggaggatt aaacttattc tttggcgcca agttagatgt
    15841 gggtacattg ttattaggaa ttggtttctt tattattact gttaaatcac cttcatttat
    15901 tcgttcaatg gtttattcaa ctggcagtgg ccgtatggct actggaatgg ctgggagttc
    15961 agctaaacta ttagtaagac aattgttaac aagataagag gaagaggtaa tattatgctt
    16021 aatagggttg tatattgtgg gagaattgct acagaattaa atgtaagaaa aagtaaaaat
    16081 aataaatcat ttttgttttt taatctagct gtacctagac aaaatgatga taaaacggat
    16141 tttattaatt gtgttgtatt taataataaa gctgaaaact tagttaagta tcaaagtaaa
    16201 ggaaatctta ttattataga aggatcaaca gaaacatata aaaaagacaa tataaatatg
    16261 agtagatgtt tagtagatag aataacttat ttagaaaata aaaaagagga tagtattcag
    16321 agtgttattg attcagaaga ggataaacac gaaaattatg acataataag tggagaagat
    16381 ttaccttttt aagtattagg aacaggagga atataagtgg aaacaatatt aggtttaata
    16441 atatttggag tttttgggtt tattatttat aactcaaatc aaaaacatta cagacgttat
    16501 caatctaaaa taaacgatta tataccttct ttaaaggaag atattcaagt cggtaaaata
    16561 aatagtattg ctacagatga acaaaataga gatgaagttg ttttcgattg ggggttttca
    16621 acatctgtta caaataaaaa tgtaatgttt gttgaatctt tggaagaaga aaaaatagaa
    16681 tttcaaatcc ctaatgcaaa atctatggac aaacactata aaaaaacttt ttcatttgta
    16741 aacgttacag ataaagattt tgaaaaatac ttatataagt atgttctagt attaggaatt
    16801 aaattatata taaccagaga aagttatgaa aagctaaaac gtaatcgaat tattacagcc
    16861 aagtaagaag aaaatcccct agttaattaa attaggggaa attttttaca aacaaaaaag
    16921 ggatacctac tatacaaggg atacatgttg tgttattatg taagtatcaa gtaaaaggaa
    16981 gaaggttatt gatatgaata agaattacta ctttgaagct aatggtaaag attattgctt
    17041 atcagtttcg aaagatgtat ttggttgtag tggcgtagct attaaggaaa atgggtgtta
    17101 tattggtatg atagattgtg cagatgaaga agattactta agaattgaaa atatcgttaa
    17161 acaagatatt gaaagtatca tcaacagtga aatttattgc tagttttttt taaaattaaa
    17221 aagggctaca aaggacacct taaaagtatc ttgtagccct ttagtaccta tattataatt
    17281 agagggatga taaaggagga ttattatgga agagaaaaat agtatgagta aaaaatacgt
    17341 tagtccctca cataaaaaga gaagatcagt gcatatttat aaaaatgttg atgatttagc
    17401 taatgagctt aaatttgatt taagacttaa tagcaaacaa gaagtttata caaaggctat
    17461 tgagaacttg tataaagaag tgcatggcaa gtcaatatca ttggatcaaa atgagtaaat
    17521 acgttaaaaa aggagtttta tcatgtataa aaaaatatta gctagtggtt taactgtttc
    17581 aatgttgctt gtaggtttga ataatgctaa tgcagaagaa aatcagataa cagagaaaac
    17641 actaacagag ggcgcagacc taaatcaaca acaagaaaaa caaacacgtg atttattcga
    17701 tgttaattca aacgttagga cttataaagt tgatagtgaa gatgttcaac attatacggg
    17761 caagtggtac gatacgattt attctagtac ctacattgaa cctaaaaagt ttaggcatgg
    17821 cgttgacgtt gaaatagtaa cacccgataa cataacagat gtatctaagg aacaataccg
    17881 aaacgctgct attactgccg gtattcaaga cgcaaatata aaagttggtg cagttgttga
    17941 aacgttagga tatggagctt tgtccggaat atataaggct tatgaaaaag aaggcagtgc
    18001 actaaatgaa caagacatca aaaatgcaga tgatgaaatg aaagaattgt ctagcataag
    18061 caaaaataat aatgaggaag aattttctga cgaagcatta aataattcag tagccgaaat
    18121 gaaacaagaa atagcaaaag aaaaagctaa tgataataat ttaagtagac aagatgtaga
    18181 aaatattgtc gatgataaat taaaagaaaa tggtttgaat aaagttttat cagataatca
    18241 aatcaattct atttataaca ttatgaataa tgtttctaat tctaaagtgt tgaatcaaga
    18301 ccctaaagca tatgagcaac aagctaaaaa actttcaagc gatattaaag ataaagcagg
    18361 gggactgatt gagaaagcta aaggattgaa cactgaagaa aatcgcaaca tcttacaaaa
    18421 gatttgggac gctatagttg attttgtgaa ttggttagtt aacttaatca aatcattatt
    18481 ttagactctg agaaaagcgt ttatttgcat cgaaaaagta atttatcggg aaaaggtaag
    18541 ccaatgcaaa tagcaatact ctaatattat aacaatcatt gaatatagtg ttttttacat
    18601 gcttagcatt caataggagg catttatcat gaacaaagaa actttagtaa gtcttataga
    18661 tgtgatgata ggattaacag atagtgaaaa acaaaaacta ttaaaaatgg ataagcgtaa
    18721 agttgaattt cgctataaaa tggcattgac tgaaaaaaca gatgaattat ttgctgaata
    18781 aaaaaggggg atatatatat ggataaaaag caagcaacac aaataattca aaacttggtt
    18841 ataattcata gaaatataca ttgggggagt attaaatctt cgccaacatc tagttgggat
    18901 agatatagta ttaattactc taaagaagaa ttcatttttt attatcaagc tttctctgaa
    18961 tatgcttgtg atttagataa ttacatgact agtgccatgg gagaaggtgt tccagagagt
    19021 gacctcccag aatttgaatc aaatgtaaga atagctatcg agcgtatgat agagtatata
    19081 gaaggatata atattaactt atatgctaaa gagaatttta ttgaaaggtc tggaataagt
    19141 gatgttttta aaatattaga tatagatcta gattcaatat taaaacgcat taatgataat
    19201 cacacttctt taataaagga atgtaagaac aattatttat ctttttacga ccaaaaaatt
    19261 aattgtactt tatcttcaat taataatgac attaacagta ataagaaatt taacaagcat
    19321 ttgttcatta gactagaagc tatgaaaaat ttaaaaaaat tagcagaaaa ggatagaaaa
    19381 atagaagacg ttacacataa aatagatact gctattttcg ataaattagt tccggaaagt
    19441 atttatcatt tagctcttac taaggaaata gaactgttaa agaaagataa aaagaaagaa
    19501 aaagtgagaa aaatttttaa gatataataa atactatcct ttaaacttca ataggagatt
    19561 aaaatgaaaa aggtatatat agataacatt aaggattata tcataattga tgatgaggat
    19621 tataattcca taaataagta caaatggcat attaatgatt attatggaac aacaagagca
    19681 ttagctttca taaatggaaa aaaagtagct ttaccatact ttattacagg tgtagtaaat
    19741 gcttatcaaa aaaacaagaa tttagatttt agaaaacaaa atattggtat tgatcaacat
    19801 aaacatagat atagaaaacc tcaaagaaat gcttctagca aatataaagg ggttagacgt
    19861 gctaaattaa gatctaatat aagatatata agctctatta aattagaaga taaaagtaag
    19921 catttaggtt gttttatttc agaaaaagaa gcagcgagag cctataacga agctgtggtt
    19981 gagtactggg gaggcaatgg ttacttaaat gatatttaag gaagtatatt ataaatttaa
    20041 aaatcgtgat taacggaggt ttgattatga aaagtaataa taatttaatt attaatatta
    20101 taggtgtagt agctacatat ttttacatta ttgcgtttaa tatagttata ttatggtttt
    20161 tattatactt gtttcataat cactttaaag gtattgaaat gtttttttct attttgttaa
    20221 ctgttattac attgatagta gctattggta tgaacaaaat attctataga attaacatga
    20281 aacattaata aactaaagat agttataata aagaaagtga aatcaattag ggtctgaact
    20341 ttatagagtg atcttttctg ttatactaga aattaaataa gtatcaaaaa cgttcgtttt
    20401 tgatagtgtg gctatgctat attataagca aagtttaaat aactaaaata aaagactata
    20461 taaagcgtaa aatcagtttt tctaatgaat aatcagtttt ttaaccaact ttatcaaaac
    20521 tcataatcaa aaacaaaaaa tcaaaacatc actttatatg gtttttgaca aaaaagaagg
    20581 gagggataat aatggctaat ataggttatg ctcgtgtttc aacaaaagat caaagtttag
    20641 attctcaaat tgatattttg aaagaatatg gttgtacaaa aatatttagt gagaaaatta
    20701 gtggccgaaa atatcaaaga aatgaattag ataagtgtct tgaatatttg agaagtggag
    20761 atacattagt gatttataaa ctggatcgct taggtcgaac tgtaaaacaa ctagtagaat
    20821 tagcacagtg gtttgaagaa aatggtattg aattagaaat tattagcatg aatataaata
    20881 ctaaagatcc aatggggaga atgtttttta ctatatcgag tgcttatgca gaacttgaag
    20941 ccgatttatt aagtcaacgc acaaaagctg gtttagaatc agcaagagct agaggtcgat
    21001 tgggtggtcg ccctccgata cccgaacata agaggagaga agtttgttat ttatataacg
    21061 aacaaaaaat gactgtatca gatatatcta aaaatactat ggttagtaag gcgagtatat
    21121 atagaattgt tagagaaaat aagcattaaa agtttgagta aataggatta taaataattg
    21181 aaaattatta agaaacatga tatattatgt ttgtaaagga atcggcgttg tggcgcagat
    21241 acaaaaatta atactacaca tttaagaatc ggcgttgtgg cgcagataca aaaattaata
    21301 ctgcatattt aagaatcggc gttgtggcgc agatacaaaa attaatactg cattgaaaag
    21361 aatatattat caatctaaag ggtcgttatt gtaacgaccc tttttttaat actagtgagg
    21421 tgcttttatg gaagttattc gtttaaatca acaattattt aactcgaaca aatttaataa
    21481 gaatgaaata gaagacaata aaaatgggaa aagaccttat ttttattctt ttaaaagaaa
    21541 taatcataga atatgtatac ctttaagaac taacacaaga agcgttccag aaagatataa
    21601 attaaaacta aatcaagttc aaccacataa acccaattcg gcgctagata caacaaaatc
    21661 tttagttata gacgaaaata catacaaagc taacaaacaa aagactagtc tacattcatc
    21721 agtatataac tatattaaaa ataatagaga tagtcttgaa aataaatttg atgtacttac
    21781 taaagattat gtaaatgcta aaggtaaaat ggctgatatt ccgttgacta aatattcaac
    21841 tctgcaatat tttcatgatg aattaaattt acagcctatc attgataata aactattgaa
    21901 aaattgcgtt aaggaactaa atgataacgg ttatacaaat aaatatgaaa acttaaaaac
    21961 agaaatacca aatttatcgg aaaccataga aagctacgaa atattaaatg aatttaaaaa
    22021 actctctaat tatccttcaa aactagtgaa tgatgatata aaaaaccccg ttcttgagat
    22081 agttaaagat aacaataaat tttcattaac tagtaataat attactgaaa acccagaaaa
    22141 acacatgaaa aatttcttag attatgaccc taaagacaga gaaaataatc ttgatttgta
    22201 aatcaaaaga gctatataac cacaacatga catgacatgt tatggtataa taaggaaaaa
    22261 ggagtgtttg ataatggctt ttgaagaaag atattttttt gaaaccaata tggatcttga
    22321 tattacgtca attcaattag gttcctctat aacttatgca ccagcaccta aaaatcaaca
    22381 agatttaacc aatcgtaata tagtaggaaa tttaatcttc aaacataact actacaatga
    22441 tgttttatca atgcctatat atgaaaagga aaataataac tacaaaatac ctattgtata
    22501 tgaaaaagaa ggtagatttt caaaaaacga taacgataat ttttatattg ataatgctga
    22561 tttttatttc actttaaata ctgcacataa aggttatgaa aaattagtta atgctataga
    22621 aaataatgaa aaagtcgaat tttcacaaaa tcaaaaccaa ttagacgact ttagtcaatt
    22681 aggagaatat agcaattatt catacgacaa tctttataat tctttagtaa aaaatattaa
    22741 ctactataat gaagtttttt ctcaatatag agagcccgaa ataaatgata ttgaaaaaat
    22801 gactgtgaat aactttgatt atgaagttaa atttaatcca gaaactcaac atatatatat
    22861 aaacaacata cctacacata gtgtaaatga acaacatgaa atacgtgttt taaatgataa
    22921 tctatctaaa aacattgaaa aagactattt taataaagat tataagtttt catataacga
    22981 ctataaaaca ttagaagata attcttatac ttatattgac ttgaatgaat acacagatag
    23041 taacaataaa tttataaaaa atttaatcga agatgtaccg cctaatgagt tgcttgtaga
    23101 ttcgataaaa caaagaatta actatgtaga tcaacaaatc aattttagag atattaatgt
    23161 acttaaaaat gatttaaata atttcgctga aattaataat ctaaccgatt tagatgaagt
    23221 taattattta aataatagct acgatgatta cttaaatata atttcaacta atatagaaaa
    23281 cgatatagag aaagacgggc ttaaaaatcg ttttatgtat ttagatgaac cttttcattt
    23341 aatgaaaaca acgacttaca cattatatga caatatagaa aatgatatac gtaatatatc
    23401 agctttagat agaaacaaaa gaagtgattt aagagaagtt ttaacttatt tacatgattc
    23461 taaaaataat attggtaatt taatatcgaa gcatgaaact agtaaatcat ctatgatttc
    23521 acaaaatagt ttatctatct tagataacga aaaattcaaa ttaaccaatc aagactttca
    23581 tactcaaaaa gaacaaatta aagctgaaag tttttacgaa ggtatgaaag cctcaaccct
    23641 ccctattaat caaataacac ctcaagaata taaaaataga gaaaatgata ttgaaattat
    23701 aagtgaattt attaaatatg ctaaatcaga agttaataat attgatttaa aacccgattt
    23761 tataaacaac aaattacaca gtaacaacaa tagcatagac tttgattcaa tattaatcgg
    23821 ttcagaggaa caacatgatg tattcttaga gaatttaaaa gaagaaagct taaaaacaaa
    23881 ggaaaagagt ctagatatat aggaggataa ctatgttgaa aacttataca gaaatactgg
    23941 gtagtgaact gccaatttat acatcaaaac ctaatgacga tatatatgta tttaatgatg
    24001 aaaaaaagga aaactgcgaa tatgaattaa taggttatta tttatatgat accgaaaacg
    24061 atttatataa agatttgttt attctagttt agagaggaag ttgaggcatg gcttattcaa
    24121 aagaaaactt taaaaaaaag aaaattgata gcattgtcga aaatttaaac aaaaagctag
    24181 atgattttag aaacaatgat gatatgtata aagaattttt agatacaact tcaaaatttc
    24241 acaattattc aataaataat atactactca ttgccgatca aaagtcagac gctactgctg
    24301 ttgctggtta taaagcttgg aaaaataagt ttgatagaca agtccagaaa ggtgctaaag
    24361 gaattaatat tatagctcca ataatcaaaa aaagagaagt tgagatgaaa gatgaaaatg
    24421 gtaatgttat aagagatata aacggtaatc ctaaaactga acgaaaacca gcaattactg
    24481 gttatagagc tcataatgta tttgatattt cagatacaaa agggaaacct ctcattactg
    24541 ctaaagacct tataaaaaca gagtttgaaa actcaaacga ttataaagat ttatataatg
    24601 agtttaaaga ttatttaaac aaagaattac gtgtatcagt tgaagaaaga atgttcatgg
    24661 aagattctaa cttaggagaa aatacaaaag gttattattc tcctaataat gatgaaatta
    24721 ttatcgcaga cgataactct tatgacttaa aatttaaaac tttaatacat gaatacgcac
    24781 actcacaact tcatggggat caagaaatat ttaatgaatc tacagaaaag caaagagcat
    24841 taagagaact tgaggctgaa agctcagctt atattgtggc aaattactat ggacttgata
    24901 cttctgatta ttcactaggc tatataagtg gttgggcaaa agatttagac gatgatacta
    24961 ttaaaaatca tataaaaaac gtacattcct ttgcacaaac cactatagaa gaaattaata
    25021 atttaccaca attttctcaa tatatagata aaaaattgga atctgaattt aataaagata
    25081 tgtacaatga tttaaataag atgattgata ctaatttaaa aaacggtttt gataaagtta
    25141 ctattattga agggaactta gaaaataaat ttgatatgaa aaaagttact gacaatactt
    25201 ttgaaaatga taagtttaaa gttactttag attataaagg gtttaatatt aacaatttgc
    25261 aagataattg caaaatcaaa ctagaaaata aattagataa taccttaaat aaaaattttg
    25321 attatacaca aacttacagc aagaatttaa ttaataatac ttcaacaata tatgttacag
    25381 ataacaatat ggaagaaaac aaagtctatc gccataatag agatattgaa gggaatgtat
    25441 taaaagaaaa atcagaacaa tctcctagtt cagaattaat tacttttgaa aaattcgtta
    25501 ataaatctgt tgaagaaaaa ggtattttaa atactatgac acatctagta caaaatggct
    25561 tcaacatggg atatgaaatg aatattaacg aaaatgataa tacagatgaa acatatataa
    25621 acatgtctaa agttgaaaaa aatggtttta aatctacgtt gacttctaaa attgaacacg
    25681 atcaatctaa taatgtttac gttgatttta aaatgaaaaa ttcctctggt ataaaaaacc
    25741 tgtcgttcaa agaaacacaa aatgagttcg aaacaaataa agataaacct ttgaagttag
    25801 aaagtaaaca gaacattgat ttatagaata aggtacatat cctcatggat atgtacctta
    25861 ttctataaat gtatccctct cttgtttcgt acttcatggc gtttcttact gtggttttta
    25921 cctttatatt gatggtttat atattttggt aatctctctc taaataactc attaaaatta
    25981 aaaataaagt tatcaaaact tgcatttatt agaccatagc cttttgatga agcatagtaa
    26041 ttattatact gttctttatc tattacaaca tcgttacttt cgtaaaattc ttctattttt
    26101 ctcttattat cattatcatt tgttaagttt gtttcttgaa ataaatgttt tatatcatta
    26161 ttatttttac agtcaaagtc aaaatcattt aataaagtct tttggactgc tcctattaca
    26221 tattcatcat attgtgattt attaggttta aactcttttt cctgcagcgt taataattta
    26281 tctaaaataa aagttctatc ctcattgtta tacttaggaa taaattttct ttcatctaac
    26341 attcttaaag tattatccac accatgataa cttttaaaat caatcaattg ttgtttttct
    26401 tcaatactcg aaacctcatt aaatgctgaa tactcatcac tatcactaaa caaatctttg
    26461 atctgaaaat tgtaataatc atccaagata ttttcagcct ttgcaattct ttctaatttc
    26521 gatatatagt aatcaatttt agattgatca tttgtactat gataactatc attttctata
    26581 tcttcaaaag ataaattatt cttttctaat agattattta acttaccttc aaaaaagtta
    26641 gattcttcct ttattgactg taaacttata tctctatttc ctaaaatcgt atttaaacta
    26701 atttctgctt ctttttgtct tttatcctca acaattctgt ctaattcagt acttgctggc
    26761 agttgatcac aatcatttaa aatatatcga gtaataaacg ttttttcatc tgatgtaaaa
    26821 ttgttttctt cttttggata atttttatta aaaaatagct ctgactgttt atcaaatatt
    26881 tcacgtactt tttctagttt tgtttctcta tcctcaatat cgtcaacttt tctcaaacgt
    26941 gtatcatcgt cactaattaa cgatgttttt tcttttaagt catataacct ttctttttct
    27001 ttaaacatat ttattggcgt gataaatagc tttaagtctt tagccatatt tttcagcaat
    27061 tttgtatcat tattattcat ataactaaaa gaatttaact tattagattt caagtcattt
    27121 atatctttgt atagattgtt gattttagac tgatttcttt tttttatctc ttcattatat
    27181 ttagaaactt cagattgtat tccggtttca tcttcaaatt tcctcgcttt ccacccttct
    27241 tttaaagttg gctctaaatc tatattttga tttttataag tttctgatga aacagttaca
    27301 ttaaaacctc tcattttcaa atgtttattt tgtatagttt cccaacgttt tctccattct
    27361 aaattttttt cttctgtatt ccaatcacga ataaatttat taccttttct cttaggttca
    27421 aattcattat tttcatctat acctcgtaat gtacatagca aatgtgcatg tggattatca
    27481 cttgaaattt tatgaatatt taaatctact atcatccctt catctgctaa agattcagaa
    27541 aaatctttag ctaattttac attattttct tcatttaatt ctgtaggtaa tccaataata
    27601 atttctcttg ctaattgact atcttttcta ttttcaacgt catgtacttt attccataaa
    27661 aattctctat ctgaatattc tacacctgca tttttaggta ataaaatttc actatagtca
    27721 cattgtttat ttgagtaatc tttatagtct ttttctttat aatcataaat cttacttgcg
    27781 ctattataag cactttttga agtagcactt tgatttttac ctcttgaaac tattttgttt
    27841 tggaaatgat aaatagccat aataaaaact cctaataaca taaattgagc gaaggcgaaa
    27901 taattaaaat tccaatttta attttaaagg ttttaagcac acgttctgaa agaacgtata
    27961 agtgcgccct tacgggattt aactagatta taacggtaaa tattgaaact gtcaagaaaa
    28021 aaggttataa ttaagaaaag atgaattgtg gaggaattat aatgtctaat attgataaaa
    28081 tgattgaaca aaagaaaaaa ttacaagaaa aaattaaaaa agaaaaagaa aaagaatatg
    28141 taaaatttgg tcgttggttt tttaacaaat tgaacataaa tagttcagct gaagcgaaaa
    28201 aaataataaa caaagattta ttatataaag atataaattc taacgataaa aatgaacatg
    28261 attcaaatgt actatatgaa gaaagtgaaa gtgtaaaata tgataaattt aacgaaaata
    28321 catcggaata agatcgcaaa tatctcaaaa tttaatatat agataacatt tatattaagg
    28381 aataaaaaaa ggaggttatt tactatgttt gtattaagtg ctatttcaga aaattctgtt
    28441 cacattaacc caatattaag atttattatt tacttcgttt tttctgtacc tctaacagtt
    28501 tgtgcactaa cttttgtaat aaaattttta actttttttc tattaccact taaaatttgt
    28561 ttttggattt ctgtattttt cggtatcatt atgacaatat ttttagcagt aatgtgtatt
    28621 gttattcctt acacataaaa tatcacatga catgacatgt gatatatgat actatttaaa
    28681 taacaattca aataagagtt gttatttttt taaaaacacc caatatatat tagtatatat
    28741 taatatatat aagtatatac aattcggagg ttatctta
//
