LOCUS       CP051409                9083 bp    DNA     circular BCT 31-DEC-2020
DEFINITION  Salmonella enterica subsp. enterica serovar Havana strain CVM 20761
            plasmid p20761-2, complete sequence.
ACCESSION   CP051409
VERSION     CP051409.1
DBLINK      BioProject: PRJNA622256
            BioSample: SAMN14504561
KEYWORDS    .
SOURCE      Salmonella enterica subsp. enterica serovar Havana
  ORGANISM  Salmonella enterica subsp. enterica serovar Havana
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 9083)
  AUTHORS   Zhao,S., Li,C., Hsu,C.H., Tyson,G.H., Strain,E., Tate,H., Tran,T.T.,
            Abbott,J. and McDermott,P.F.
  TITLE     Comparative Genomic Analysis of 450 Strains of Salmonella enterica
            Isolated from Diseased Animals
  JOURNAL   Genes (Basel) 11 (9), E1025 (2020)
   PUBMED   32883017
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9083)
  AUTHORS   Li,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-APR-2020) CVM/OR, FDA-CVM, 8401 Muirkirk Rd, MOD2,
            Laurel, MD 20708, United States of America
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 4
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 607x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 04/14/2020 13:16:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 4.11
            Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region
            Genes (total)                     :: 4,704
            CDSs (total)                      :: 4,582
            Genes (coding)                    :: 4,123
            CDSs (with protein)               :: 4,123
            Genes (RNA)                       :: 122
            rRNAs                             :: 8, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 85
            ncRNAs                            :: 15
            Pseudo Genes (total)              :: 459
            CDSs (without protein)            :: 459
            Pseudo Genes (ambiguous residues) :: 0 of 459
            Pseudo Genes (frameshifted)       :: 412 of 459
            Pseudo Genes (incomplete)         :: 51 of 459
            Pseudo Genes (internal stop)      :: 20 of 459
            Pseudo Genes (multiple problems)  :: 20 of 459
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..9083
                     /organism="Salmonella enterica subsp. enterica serovar
                     Havana"
                     /mol_type="genomic DNA"
                     /strain="CVM 20761"
                     /serovar="Havana"
                     /isolation_source="swine"
                     /sub_species="enterica"
                     /db_xref="taxon:179997"
                     /plasmid="p20761-2"
                     /geo_loc_name="USA:NC"
                     /collection_date="2002"
                     /collected_by="NC State Veterinary Diagnostic Lab"
     gene            complement(join(8195..9083,1..14))
                     /locus_tag="HFQ57_23465"
     CDS             complement(join(8195..9083,1..14))
                     /locus_tag="HFQ57_23465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020229253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="QQJ14337.1"
                     /translation="MRSDPAGSAVCPDLLFTAIAPAIWGSTYIVTTQYLPNFSPMTVAM
                     LRALPAGLLLVMIVRQIPTGIWWMRIFILGALNISLFWSLLFISVYRLPGGVAATVGAV
                     QPLMVVFISAALLGSPIRLMAVLGAICGTAGVALLVLTPNAALDPVGVAAGLAGAVSMA
                     FGTVLTRKWQPPVPLLTFTAWQLAAGGLLLVPVALVFDPPIPMPTGTNVLGLAWLGLIG
                     AGLTYFLWFRGISRLEPTVVSLLGFLSPGTAVLLGWLFLDQTLSALQIIGVLLVIGSIW
                     LGQRSNRTPRARIACRKSP"
                     /name="EamA family transporter"
     gene            complement(265..933)
                     /locus_tag="HFQ57_23470"
     CDS             complement(265..933)
                     /locus_tag="HFQ57_23470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="QQJ14340.1"
                     /translation="MAQAAARGQLDLHYQPLVDLRDHRIAGAEALMRWRHPRLGLLPPG
                     QFLPLAESFGLMPEIGAWVLGEACRQMHKWQGPAWQPFRLAINVSASQVGPTFDDEVKR
                     VLADMALPAELLEIELTESVAFGNPALFASFDALRAIGVRFAADDFGTGYSCLQHLKCC
                     PITTLKIDQSFVARLPDDARDQTIVRAVIQLAHGLGMDVIFRRRLHQLIGRNGCCAASS
                     "
                     /name="EAL domain-containing protein"
     gene            complement(969..1205)
                     /gene="merE"
                     /locus_tag="HFQ57_23475"
     CDS             complement(969..1205)
                     /gene="merE"
                     /locus_tag="HFQ57_23475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="broad-spectrum mercury transporter MerE"
                     /protein_id="QQJ14329.1"
                     /translation="MNAPDKLPPETRQPVSGYLWGALAVLTCPCHLPILAAVLAGTTAG
                     AFLGEHWGVAALALTGLFVLAVTRLLRAFRGGS"
                     /name="merE"
     gene            complement(1202..1564)
                     /gene="merD"
                     /locus_tag="HFQ57_23480"
     CDS             complement(1202..1564)
                     /gene="merD"
                     /locus_tag="HFQ57_23480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mercury resistance co-regulator MerD"
                     /protein_id="QQJ14330.1"
                     /translation="MSAYTVSQLAHNAGVSVHIVRDYLVRGLLRPVACTTGGYGVFDDA
                     ALQRLCFVRAAFEAGIGLDALARLCRALDAADGAQAAAQLAVLRQLVERRRAALAHLDA
                     QLASMPAERAHEEALP"
                     /name="merD"
     gene            complement(1582..3276)
                     /locus_tag="HFQ57_23485"
     CDS             complement(1582..3276)
                     /locus_tag="HFQ57_23485"
                     /EC_number="1.16.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004636758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mercury(II) reductase"
                     /protein_id="QQJ14331.1"
                     /translation="MSTLKITGMTCDSCAVHVKDALEKVPGVQSADVSYAKGSAKLAIE
                     VGTSPDALTAAVAGLGYRATLADAPSVSTPGGLLDKMRDLLGRNDKTGSSGALHIAVIG
                     SGGAAMAAALKAVEQGARVTLIERGTIGGTCVNVGCVPSKIMIRAAHIAHLRRESPFDG
                     GIAATTPTIQRTALLAQQQARVDELRHAKYEGILEGNPAITVLHGSARFKDNRNLIVQL
                     NDGGERVVAFDRCLIATGASPAVPPIPGLKDTPYWTSTEALVSETIPKRLAVIGSSVVA
                     LELAQAFARLGAKVTILARSTLFFREDPAIGEAVTAAFRMEGIEVREHTQASQVAYING
                     EGDGEFVLTTAHGELRADKLLVATGRAPNTRKLALDATGVTLTPQGAIVIDPGMRTSVE
                     HIYAAGDCTDQPQFVYVAAAAGTRAAINMTGGDAALNLTAMPAVVFTDPQVATVGYSEA
                     EAHHDGIKTDSRTLTLDNVPRALANFDTRGFIKLVVEEGSGRLIGVQAVAPEAGELIQT
                     AALAIRNRMTVQELADQLFPYLTMVEGLKLAAQTFNKDVKQLSCCAG"
                     /name="mercury(II) reductase"
     gene            complement(3328..3750)
                     /gene="merC"
                     /locus_tag="HFQ57_23490"
     ARG             complement(3332..3750)
                     /name="merC"
                     /gene="merC"
                     /gene_name="organomercurial transporter MerC"
                     /tool="amrfinderplus"
                     /drug_class="MERCURY"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(3786..4061)
                     /gene="merP"
                     /locus_tag="HFQ57_23495"
     CDS             complement(3786..4061)
                     /gene="merP"
                     /locus_tag="HFQ57_23495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004636750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mercury resistance system periplasmic binding
                     protein MerP"
                     /protein_id="QQJ14332.1"
                     /translation="MKKLFASLALAAAVAPVWAATQTVTLAVPGMTCAACPITVKKALS
                     KVEGVSKVDVGFEKREAVVTFDDTKASVQKLTKATADAGYPSSVKQ"
                     /name="merP"
     gene            complement(4075..4425)
                     /locus_tag="HFQ57_23500"
     CDS             complement(4075..4425)
                     /locus_tag="HFQ57_23500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011111453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mercuric transport protein MerT"
                     /protein_id="QQJ14333.1"
                     /translation="MSEPQNGRGALFAGGLAAILASTCCLGPLVLVALGFSGAWIGNLT
                     VLEPYRPLFIGAALVALFFAWKRIYRPVQACKPGEVCAIPQVRATYKLIFWIVAVLVLV
                     ALGFPYVVPFFY"
                     /name="mercuric transport protein MerT"
     gene            4497..4931
                     /gene="merR"
                     /locus_tag="HFQ57_23505"
     CDS             4497..4931
                     /gene="merR"
                     /locus_tag="HFQ57_23505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hg(II)-responsive transcriptional regulator"
                     /protein_id="QQJ14334.1"
                     /translation="MENNLENLTIGVFAKAAGVNVETIRFYQRKGLLREPDKPYGSIRR
                     YGEADVVRVKFVKSAQRLGFSLDEIAELLRLDDGTHCEEASSLAEHKLKDVREKMADLA
                     RMETVLSELVCACHARKGNVSCPLIASLQGEAGLARSAMP"
                     /name="merR"
     gene            5934..6176
                     /locus_tag="HFQ57_23510"
     CDS             5934..6176
                     /locus_tag="HFQ57_23510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase"
                     /protein_id="QQJ14335.1"
                     /translation="MKTAALDLARERQAHEAGARTRATAHERTPQQERQKAAREAERGR
                     EAWTLGQGMKKPVAGCYGRLTRWKGGGDVVYMALL"
                     /name="relaxase"
     gene            complement(6208..6858)
                     /gene="tetR(A)"
                     /locus_tag="HFQ57_23515"
     CDS             complement(6208..6858)
                     /gene="tetR(A)"
                     /locus_tag="HFQ57_23515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance transcriptional repressor
                     TetR(A)"
                     /protein_id="QQJ14339.1"
                     /translation="MTKLQPNTVIRAALDLLNEVGVDGLTTRKLAERLGVQQPALYWHF
                     RNKRALLDALAEAMLAENHTHSVPRADDDWRSFLIGNARSFRQALLAYRDGARIHAGTR
                     PGAPQMETADAQLRFLCEAGFSAGDAVNALMTISYFTVGAVLEEQAGDSDAGERGGTVE
                     QAPLSPLLRAAIDAFDEAGPDAAFEQGLAVIVDGLAKRRLVVRNVEGPRKGDD"
                     /name="tetR(A)"
     gene            6964..8163
                     /gene="tet(A)"
                     /locus_tag="HFQ57_23520"
     ARG             6965..8160
                     /name="tet(A)"
                     /gene="tet(A)"
                     /gene_name="tetracycline efflux MFS transporter Tet(A)"
                     /tool="amrfinderplus"
                     /drug_class="TETRACYCLINE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(4079..4425)
                     /name="merT"
                     /gene="merT"
                     /gene_name="mercuric transport protein MerT"
                     /tool="amrfinderplus"
                     /drug_class="MERCURY"
                     /identity="100.0"
                     /coverage="100.0"
ORIGIN
        1 ggatcagaac gtatacctgg cgccgagaca agcccagcgc ctgagccgcc atatcggccg
       61 cttcgtgccc gaccgtctcc gactgcgcca acggactgat gatctccgca cgacggcgcg
      121 cacgctccca agcctcatca ggcagagtgg ccacgccttg ttctggaatc cgtggggtgt
      181 ccgtcgccat gctcacctcg ctttggtgca cacgagtatt gagcatagtc gagattggtg
      241 cagatcactt ctgatattga actgtcagga gctggctgca caacagccat tacgcccaat
      301 caactggtgc agtcgtcttc tgaaaatgac atccatgccc agcccgtgcg cgagctggat
      361 caccgcccgc acgatagttt ggtcacgggc atcatccggg agcctggcga caaaggattg
      421 gtcgattttc aatgtggtga tggggcagca tttcagatgt tgcaggcagg aatagccggt
      481 gccgaagtcg tcggcggcga agcgcacgcc gatggcgcgc aaggcgtcga aactggcgaa
      541 cagggctgga ttgccgaatg cgaccgattc ggtcagttcg atctccagaa gctcggcggg
      601 cagggccata tcggccagca cccgctttac ctcgtcgtcg aacgttggcc caacctggct
      661 ggcggacaca ttgatggcaa gacggaacgg ttgccatgcc ggtccttgcc acttgtgcat
      721 ctggcgacag gcctcgccca gcacccacgc gcctatttcc ggcatcaggc cgaacgactc
      781 ggccagcggc aggaactggc cgggcggcaa caggccaagc ctcggatgcc gccagcgcat
      841 caacgcttcc gcgccagcga tccggtgatc gcgcagatcg accagcggct ggtaatgcag
      901 gtcaagctgt ccgcgcgccg ccgcctgcgc caactcggcc gccgtccatc cggcgggctg
      961 cgaactcgtc atgatccgcc ccggaaggcg cgcagcagcc gcgttacggc cagaacgaac
     1021 aagccggtca gcgcgagcgc ggcaacaccc caatgctcgc caaggaaggc accggcggtc
     1081 gtcccggcca gcacggcggc gagaatcggc agatggcagg ggcaggtcaa cacggccagc
     1141 gcaccccaca ggtagccgga aacgggttgg cgcgtctcgg gcggcagttt gtcaggggcg
     1201 ttcacggcaa tgcctcctcg tgcgcccgct cggctggcat ggaggccagt tgcgcgtcca
     1261 gatgggccaa cgccgcgcgc cgccgctcga ccaactggcg cagcacggca agctgcgctg
     1321 cggcttgtgc gccgtccgct gcgtcgagcg cacggcacag ccgcgccagg gcatccaggc
     1381 cgatacccgc ctcgaaggcc gcgcgcacga agcacagccg ttgcaaggcc gcatcgtcga
     1441 acacgccgta gccgcccgtg gtgcaggcca ccggccgtaa caagccgcgc accaggtagt
     1501 cgcgcacgat atgtacgctc accccagcgt tatgggccag ttgcgatacc gtgtaggcgc
     1561 tcatcgcaca cctccttgtc ctcacccggc gcagcaggaa agctgcttca catccttgtt
     1621 gaaggtctgc gccgcgagct tcaacccttc gaccatcgtc aggtagggga acaactggtc
     1681 ggccagttcc tgcaccgtca tccggttgcg aatcgccagt gcggccgtct ggatcagttc
     1741 gcccgcttcc ggggccactg cctgcacgcc gatcagtcgt ccgctgcctt cttcaaccac
     1801 cagtttgatg aagccgcgcg tgtcgaagtt ggcgagcgcg cgcggcacgt tgtccagcgt
     1861 tagcgtgcga ctatcagttt tgatgccgtc atggtgcgct tccgcctcgc tgtagcctac
     1921 ggtcgccact tgcgggtcgg tgaacaccac ggccggcatc gcggtcaggt tcagggccgc
     1981 gtcaccgccg gtcatgttga tcgcggcgcg agtgccggcc gctgccgcca catagacgaa
     2041 ctgcggctgg tcggtgcagt cgcctgcggc gtagatgtgt tccacgcttg tacgcatgcc
     2101 ggggtcgatg acgatagcgc cttgcggggt gagcgtgacg cccgtcgcat ccagtgccag
     2161 cttgcgtgtg ttgggcgcgc ggccggtggc gaccagcagc ttgtcggcgc gcagttcgcc
     2221 gtgcgccgtg gtgagcacga attcgccgtc cccttcacca ttgatatacg cgacctggct
     2281 ggcctgggtg tgttccctca cctcgatgcc ctccatgcgg aatgcggccg tgacggcttc
     2341 gcctatagct gggtcttcgc ggaagaacag cgtgctgcga gccaggatcg tcaccttcgc
     2401 tccgagtcgg gcgaacgcct gcgccagctc cagcgccacc actgatgagc caatcacggc
     2461 caggcgctta ggaatcgtct cgctgaccag cgcttcagtg gaagtccagt acggagtgtc
     2521 tttcaggccg ggaatcggcg gcacggccgg gctcgcgccg gtggcgatca ggcagcggtc
     2581 gaatgccacc acgcgctcgc cgccgtcgtt gagttgcacg atcaggttgc gattgtcctt
     2641 aaagcgggcg gagccgtgca gcacagtgat cgccggattg ccctccaaga tgccttcgta
     2701 cttggcgtgg cgcagttcat cgacgcgggc ctgctgctgg gccagcagcg ccgtgcgctg
     2761 gatggtcggc gtggtagcgg cgatgccgcc atcgaacggg ctttcccggc gcagatgggc
     2821 gatatgggcg gcgcggatca tgatcttgga cggcacacaa ccgacattga cgcaggtgcc
     2881 gccgatggtg ccgcgctcga tcagcgtgac acgtgcgcct tgctcgacgg ccttcagcgc
     2941 cgctgccatc gcggccccgc cgctgccgat gacggcgata tgcaatgcgc cgctgctacc
     3001 cgtcttgtcg tttctgccca gcagatcgcg catcttgtcg agcaatccgc ccggcgtcga
     3061 aactgagggg gcatcggcca gcgtggcccg ataaccgagt ccagctacag cggccgtcag
     3121 cgcgtcgggt gacgtgccga cctcaatggc gagcttggcg ctgcccttgg cgtaggagac
     3181 atccgctgat tgcacgccgg gcactttctc cagggcgtcc ttgacatgca ctgcgcacga
     3241 gtcgcaagtc atgccggtga ttttgagagt gctcatacca tcgttcctta ttcgtgtggg
     3301 ccgccgtgtc gcacggtcag ccgtctttca caagcgcttg gcggggagtt cgcagccgtc
     3361 cggtccgcaa cggcgatgcg ccggcgacac gaagtcccag atcgacaccc caatcatcaa
     3421 ggccaggccg acgtacatca ggttcgccgt ccaccagttg ccgagcagcc agaccgtggc
     3481 cgcaaacacg atggccgggc cgatcatgcc gagcagactg cgcagccatt gccgatgact
     3541 gaaccaaccc agcgcgttcg ccaggaaggc cagcgcggca aacagcggca gcaggcggct
     3601 gatgaacagt ccctcgtact ggctcaagaa gcccagcccg atggccgcgc cgaagctggc
     3661 gagggctgga aagcaggcgg cgcagcccat cgcggaaacg acgctgccga gcgcgccggt
     3721 tttatcggca atgcgtgtca tcagtcccat gaagcggctc tcgctgttgt cgttggcttg
     3781 ctggctcact gcttgacgct ggacggatag ccggcgtctg cggtggcctt ggtcagcttc
     3841 tgtacgctgg ccttggtgtc gtcaaaagtg acgacggcct cgcgcttctc gaagcccaca
     3901 tcgaccttgc tcacgccttc gaccttggag agcgctttct tgactgtgat cgggcaggcg
     3961 gcgcaagtca tgccgggaac cgctagcgtg acggtctggg tagcggccca caccggggca
     4021 acagcggcgg cgagggcaag ggaggcaaac agtttcttca tgatgaactc ctggttaata
     4081 gaaaaatgga acgacatagg gaaatccaag cgcgaccagg accagcacgg ccacgatcca
     4141 gaaaatcagc ttgtaggtgg cgcgcacctg cggaatcgcg cagacctcac ctggcttgca
     4201 tgcctgcacg ggccggtaaa tccgcttcca ggcgaagaac agcgccacta gcgccgcgcc
     4261 gatgaacaac ggtcgatagg gttccagcac cgtcaggttg ccgatccaag caccggagaa
     4321 gcccagggcg accagtacta gcggccccag gcagcaggtc gatgcaagaa tggcggccag
     4381 cccgccggcg aagagcgcac cgcgcccgtt ttgtggttca gacatacgtt ggcccttttg
     4441 aatttggatt ggatagcgta accttacttc cgtactcatg tacggagtca agcgatatgg
     4501 aaaataattt ggaaaacctg accattggcg tttttgccaa ggcggccggg gtcaacgtgg
     4561 agacaatccg cttctatcag cgcaagggcc tgttgcggga accggacaag ccttacggca
     4621 gcatccgccg ctatggggag gcggacgtgg ttcgggtgaa attcgtgaaa tcggcacagc
     4681 ggctggggtt cagtctggac gagattgccg agctgttgcg gctcgacgat ggcacccact
     4741 gcgaggaggc cagcagcctg gccgaacaca agctcaagga cgtgcgcgag aagatggccg
     4801 acttggcgcg catggaaacc gtgctgtctg aactcgtgtg cgcctgccat gcacgaaagg
     4861 ggaatgtttc ctgcccgttg atcgcgtcac tacagggcga agcaggcctg gcaaggtcag
     4921 ctatgcctta gcgtgcttta ttttccgttt tctgaggtgc cccctaattg agcatttcca
     4981 ggcgcttgcg cctggtcaac gaaagagtca gcgccgtagg cgctgccatt tttggggtga
     5041 ggccgttcgc ggccgagggg cgcagcccct ggggggatgg gaggcccgcg ttagcgggcc
     5101 gggagggttc gagaaggggg ggcacccccc ttcggcgtgc gcggtcacgc gcacagggcg
     5161 cagccctggt taaaaacaag gtttataaat attggtttaa aagcaggtta aaagacaggt
     5221 tagcggtggc cgaaaaacgg gcggaaaccc ttgcaaatgc tggattttct gcctgtggac
     5281 agcccctcaa atgtcaatag gtgcgcccct catctgtcag cactctgccc ctcaagtgtc
     5341 aaggatcgcg cccctcatct gtcagtagtc gcgcccctca agtgtcaata ccgcagggca
     5401 cttatcccca ggcttgtcca catcatctgt gggaaactcg cgtaaaatca ggcgttttcg
     5461 ccgatttgcg aggctggcca gctccacgtc gccggccgaa atcgagcctg cccctcatct
     5521 gtcaacgccg cgccgggtga gtcggcccct caagtgtcaa cgtccgcccc tcatctgtca
     5581 gtgagggcca agttttccgc gaggtatcca caacgccggc ggccgcggtg tctcgcacac
     5641 ggcttcgacg gcgtttctgg cgcgtttgca gggccataga cggccgccag cccagcggcg
     5701 agggcaacca gcccggtgag cgtcggaaag gcgctggaag ccccgtagcg acgcggagag
     5761 gggcgagaca agccaagggc gcaggctcga tgcgcagcac gacatagccg gttctcgcaa
     5821 ggacgagaat ttccctgcgg tgcccctcaa gtgtcaatga aagtttccaa cgcgagccat
     5881 tcgcgagagc cttgagtcca cgctagatct atctcatctg cgcaaggcag aacgtgaaga
     5941 cggccgccct ggacctcgcc cgcgagcgcc aggcgcacga ggccggcgcg cggacccgcg
     6001 ccacggccca cgagcggacg ccgcagcagg agcgccagaa ggccgccaga gaggccgagc
     6061 gcggccgtga ggcttggacg ctagggcagg gcatgaaaaa gcccgtagcg ggctgctacg
     6121 ggcgtctgac gcggtggaaa gggggagggg atgttgtcta catggctctg ctgtagtgag
     6181 tgggttgcgc tccggcagcg gtcctgatca atcgtcaccc tttctcggtc cttcaacgtt
     6241 cctgacaacg agcctccttt tcgccaatcc atcgacaatc accgcgagtc cctgctcgaa
     6301 cgctgcgtcc ggaccggctt cgtcgaaggc gtctatcgcg gcccgcaaca gcggcgagag
     6361 cggagcctgt tcaacggtgc cgccgcgctc gccggcatcg ctgtcgccgg cctgctcctc
     6421 aagcacggcc ccaacagtga agtagctgat tgtcatcagc gcattgacgg cgtccccggc
     6481 cgaaaaaccc gcctcgcaga ggaagcgaag ctgcgcgtcg gccgtttcca tctgcggtgc
     6541 gcccggtcgc gtgccggcat ggatgcgcgc gccatcgcgg taggcgagca gcgcctgcct
     6601 gaagctgcgg gcattcccga tcagaaatga gcgccagtcg tcgtcggctc tcggcaccga
     6661 atgcgtatga ttctccgcca gcatggcttc ggccagtgcg tcgagcagcg cccgcttgtt
     6721 cctgaagtgc cagtaaagcg ccggctgctg aacccccaac cgttccgcca gtttgcgtgt
     6781 cgtcagaccg tctacgccga cctcgttcaa caggtccagg gcggcacgga tcactgtatt
     6841 cggctgcaac tttgtcatgc ttgacacttt atcactgata aacataatat gtccaccaac
     6901 ttatcagtga taaagaatcc gcgcgttcaa tcggaccagc ggaggctggt ccggaggcca
     6961 gacgtgaaac ccaacagacc cctgatcgta attctgagca ctgtcgcgct cgacgctgtc
     7021 ggcatcggcc tgattatgcc ggtgctgccg ggcctcctgc gcgatctggt tcactcgaac
     7081 gacgtcaccg cccactatgg cattctgctg gcgctgtatg cgttgatgca atttgcctgc
     7141 gcacctgtgc tgggcgcgct gtcggatcgt ttcgggcggc ggccggtctt gctcgtctcg
     7201 ctggccggcg ctgctgtcga ctacgccatc atggcgacgg cgcctttcct ttgggttctc
     7261 tatatcgggc ggatcgtggc cggcatcacc ggggcgactg gggcggtagc cggcgcttat
     7321 attgccgata tcactgatgg cgatgagcgc gcgcggcact tcggcttcat gagcgcctgt
     7381 ttcgggttcg ggatggtcgc gggacctgtg ctcggtgggc tgatgggcgg tttctccccc
     7441 cacgctccgt tcttcgccgc ggcagccttg aacggcctca atttcctgac gggctgtttc
     7501 cttttgccgg agtcgcacaa aggcgaacgc cggccgttac gccgggaggc tctcaacccg
     7561 ctcgcttcgt tccggtgggc ccggggcatg accgtcgtcg ccgccctgat ggcggtcttc
     7621 ttcatcatgc aacttgtcgg acaggtgccg gccgcgcttt gggtcatttt cggcgaggat
     7681 cgctttcact gggacgcgac cacgatcggc atttcgcttg ccgcatttgg cattctgcat
     7741 tcactcgccc aggcaatgat caccggccct gtagccgccc ggctcggcga aaggcgggca
     7801 ctcatgctcg gaatgattgc cgacggcaca ggctacatcc tgcttgcctt cgcgacacgg
     7861 ggatggatgg cgttcccgat catggtcctg cttgcttcgg gtggcatcgg aatgccggcg
     7921 ctgcaagcaa tgttgtccag gcaggtggat gaggaacgtc aggggcagct gcaaggctca
     7981 ctggcggcgc tcaccagcct gacctcgatc gtcggacccc tcctcttcac ggcgatctat
     8041 gcggcttcta taacaacgtg gaacgggtgg gcatggattg caggcgctgc cctctacttg
     8101 ctctgcctgc cggcgctgcg tcgcgggctt tggagcggcg cagggcaacg agccgatcgc
     8161 tgatcgtgga aacgataggc ctatgccatg cgggtcaagg cgacttccgg caagctatac
     8221 gcgccctagg agtgcggttg gaacgttggc ccagccagat actcccgatc acgagcagga
     8281 cgccgatgat ttgaagcgca ctcagcgtct gatccaagaa caaccatcct agcaacacgg
     8341 cggtccccgg gctgagaaag cccagtaagg aaacaactgt aggttcgagt cgcgagatcc
     8401 cccggaacca aaggaagtag gttaaacccg ctccgatcag gccgagccac gccaggccga
     8461 gaacattggt tcctgtaggc atcgggattg gcggatcaaa cactaaagct actggaacga
     8521 gcagaagtcc tccggccgcc agttgccagg cggtaaaggt gagcagaggc acgggaggtt
     8581 gccacttgcg ggtcagcacg gttccgaacg ccatggaaac cgcccccgcc aggcccgctg
     8641 cgacgccgac aggatctagc gctgcgtttg gtgtcaacac caacagcgcc acgcccgcag
     8701 ttccgcaaat agcccccagg accgccatca atcgtatcgg gctacctagc agagcggcag
     8761 agatgaacac gaccatcagc ggctgcacag cgcctaccgt cgccgcgacc ccgcccggca
     8821 ggcggtagac cgaaataaac aacaagctcc agaatagcga aatattaagt gcgccgagga
     8881 tgaagatgcg catccaccag attcccgttg gaatctgtcg gacgatcatc acgagcaata
     8941 aacccgccgg caacgcccgc agcatcgcga ccgtcatcgg tgagaagttc ggcaggtatt
     9001 gggtggtgac aatgtaggtg ctgccccaaa tggcaggtgc tatcgctgtg aacaataaat
     9061 cggggcagac ggcgcttcca gcg
//
