LOCUS       CP049571               25386 bp    DNA     circular BCT 24-SEP-2020
DEFINITION  Staphylococcus aureus strain pt177 plasmid pER04928.3A.1, complete
            sequence.
ACCESSION   CP049571
VERSION     CP049571.1
DBLINK      BioProject: PRJNA470993
            BioSample: SAMN12330994
KEYWORDS    .
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 25386)
  AUTHORS   Caban,A.B., Pak,T., Kumaresh,A., Dupper,A., Chacko,K.,
            Sullivan,M.J., Altman,D.R. and van Bakel,H.
  TITLE     PathoSPOT genomic surveillance reveals prolonged under the radar
            outbreaks of nosocomial methicillin resistant S. aureus bloodstream
            infections
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 25386)
  AUTHORS   Caban,A.B., Pak,T., Kumaresh,A., Dupper,A., Chacko,K.,
            Sullivan,M.J., Altman,D.R. and van Bakel,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-FEB-2020) Genetics and Genomic Sciences, Icahn School
            of Medicine, One Gustave L. Levy Place Box 1498, New York, NY 10029,
            USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.3.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 361.159216878403x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/28/2020 16:58:38
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 4.11
            Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region
            Genes (total)                     :: 3,040
            CDSs (total)                      :: 2,960
            Genes (coding)                    :: 2,881
            CDSs (with protein)               :: 2,881
            Genes (RNA)                       :: 80
            rRNAs                             :: 6, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 45 of 79
            Pseudo Genes (incomplete)         :: 27 of 79
            Pseudo Genes (internal stop)      :: 19 of 79
            Pseudo Genes (multiple problems)  :: 12 of 79
            ##Genome-Annotation-Data-END##
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..25386
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="pt177"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="pER04928.3A.1"
                     /geo_loc_name="USA:New York City"
                     /lat_lon="40.7903114 N 73.9528738 W"
                     /collection_date="2016"
                     /collected_by="Mount Sinai Hospital"
     gene            join(25185..25386,1..2)
                     /locus_tag="FPO40_15050"
     CDS             join(25185..25386,1..2)
                     /locus_tag="FPO40_15050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001627151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP kinase"
                     /protein_id="QNZ86225.1"
                     /translation="MGFIEQIKAFILGVVEGLTEFAPVSSTGHMIIVDDMWLNTADDLG
                     SASATTFKVVIQLGGSVAKLNL"
                     /name="UDP kinase"
     gene            32..706
                     /locus_tag="FPO40_15055"
     CDS             32..706
                     /locus_tag="FPO40_15055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="QNZ86201.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            847..1482
                     /locus_tag="FPO40_15060"
                     /pseudo=""
     CDS             847..1482
                     /locus_tag="FPO40_15060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="internal stop; incomplete; partial on complete
                     genome; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /name="aminoglycoside 6-adenylyltransferase"
     gene            1479..2009
                     /gene="sat4"
                     /locus_tag="FPO40_15065"
     ARG             1480..2006
                     /name="sat4"
                     /gene="sat4"
                     /gene_name="streptothricin N-acetyltransferase Sat4"
                     /tool="amrfinderplus"
                     /drug_class="STREPTOTHRICIN"
                     /identity="97.78"
                     /coverage="100.0"
     gene            2102..2896
                     /gene="aph(3')-IIIa"
                     /locus_tag="FPO40_15070"
     ARG             2103..2893
                     /name="aph(3')-IIIa"
                     /gene="aph(3')-IIIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(3004..3192)
                     /locus_tag="FPO40_15075"
                     /pseudo=""
     CDS             complement(3004..3192)
                     /locus_tag="FPO40_15075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913594.1"
                     /note="incomplete; partial on complete genome; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            3172..3692
                     /locus_tag="FPO40_15080"
                     /pseudo=""
     CDS             3172..3692
                     /locus_tag="FPO40_15080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="frameshifted; incomplete; partial on complete
                     genome; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /name="HTH domain-containing protein"
     gene            complement(3868..4542)
                     /locus_tag="FPO40_15085"
     CDS             complement(3868..4542)
                     /locus_tag="FPO40_15085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="QNZ86204.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            4804..4989
                     /locus_tag="FPO40_15090"
     CDS             4804..4989
                     /locus_tag="FPO40_15090"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QNZ86205.1"
                     /translation="MNKLEKWSLVFIIFTFLSSLALLYFKYNFSSVMPVLSLSILTILI
                     LLTSIITVVSVNDEDT"
                     /name="hypothetical protein"
     gene            complement(5212..5790)
                     /locus_tag="FPO40_15095"
     CDS             complement(5212..5790)
                     /locus_tag="FPO40_15095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="QNZ86206.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEAKENKNK"
                     /name="recombinase family protein"
     gene            complement(6054..6434)
                     /gene="blaI"
                     /locus_tag="FPO40_15100"
     ARG             complement(6058..6434)
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.21"
                     /coverage="100.0"
     gene            complement(6424..8181)
                     /gene="blaR1"
                     /locus_tag="FPO40_15105"
     ARG             complement(6428..8181)
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="98.8"
                     /coverage="100.0"
     gene            8288..9133
                     /gene="blaZ"
                     /locus_tag="FPO40_15110"
     ARG             8289..9130
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="99.29"
                     /coverage="100.0"
     gene            complement(9647..10066)
                     /locus_tag="FPO40_15115"
     CDS             complement(9647..10066)
                     /locus_tag="FPO40_15115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="QNZ86210.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            10190..11161
                     /locus_tag="FPO40_15120"
     CDS             10190..11161
                     /locus_tag="FPO40_15120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="QNZ86211.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFEEFYKTIDQLLKGQHLGRTILKV"
                     /name="oxidoreductase"
     gene            complement(11333..11425)
                     /locus_tag="FPO40_15125"
     CDS             complement(11333..11425)
                     /locus_tag="FPO40_15125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="QNZ86212.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(11582..11929)
                     /locus_tag="FPO40_15130"
     CDS             complement(11582..11929)
                     /locus_tag="FPO40_15130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="QNZ86213.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(11948..12565)
                     /gene="cadD"
                     /locus_tag="FPO40_15135"
     ARG             complement(11952..12565)
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(13681..13875)
                     /locus_tag="FPO40_15140"
     CDS             complement(13681..13875)
                     /locus_tag="FPO40_15140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QNZ86215.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     gene            13985..14677
                     /locus_tag="FPO40_15145"
     CDS             13985..14677
                     /locus_tag="FPO40_15145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QNZ86216.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVE
                     YKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTA
                     FAAGCSVG"
                     /name="hypothetical protein"
     gene            complement(14845..14994)
                     /locus_tag="FPO40_15150"
     CDS             complement(14845..14994)
                     /locus_tag="FPO40_15150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QNZ86217.1"
                     /translation="MKIKTFATFTHRQLDKQVNRFLKNDIHVLEIQTHSNWLYISAIVF
                     YEDK"
                     /name="hypothetical protein"
     gene            complement(15541..15857)
                     /locus_tag="FPO40_15155"
                     /pseudo=""
     CDS             complement(15541..15857)
                     /locus_tag="FPO40_15155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002483623.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            complement(15850..16833)
                     /locus_tag="FPO40_15160"
     CDS             complement(15850..16833)
                     /locus_tag="FPO40_15160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="QNZ86218.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNK
                     PNILYLMKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSKIERPEVRK
                     SNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNQFTHNFDDKEMLLQEFPE
                     QLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHD
                     RGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication initiator protein A"
     gene            17259..18002
                     /locus_tag="FPO40_15165"
     CDS             17259..18002
                     /locus_tag="FPO40_15165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002508633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="QNZ86219.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     gene            complement(18471..19370)
                     /gene="mph(C)"
                     /locus_tag="FPO40_15170"
     ARG             complement(18475..19370)
                     /name="mph(C)"
                     /gene="mph(C)"
                     /gene_name="Mph(C) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(19469..20935)
                     /gene="msr(A)"
                     /locus_tag="FPO40_15175"
     ARG             complement(19473..20935)
                     /name="msr(A)"
                     /gene="msr(A)"
                     /gene_name="ABC-F type ribosomal protection protein Msr(A)"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            21409..22083
                     /locus_tag="FPO40_15180"
     CDS             21409..22083
                     /locus_tag="FPO40_15180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="QNZ86222.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            22141..22518
                     /locus_tag="FPO40_15185"
                     /pseudo=""
     CDS             22141..22518
                     /locus_tag="FPO40_15185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866106.1"
                     /note="incomplete; partial on complete genome; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /name="response regulator transcription factor"
     gene            22515..23396
                     /locus_tag="FPO40_15190"
                     /pseudo=""
     CDS             22515..23396
                     /locus_tag="FPO40_15190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501406.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /name="HAMP domain-containing histidine kinase"
     gene            23512..24441
                     /locus_tag="FPO40_15195"
     CDS             23512..24441
                     /locus_tag="FPO40_15195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000074567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="QNZ86223.1"
                     /translation="MKNLNNIIEINNLTKQYGSQIAVNNLSITVESGQIYGFLGRNGAG
                     KTTTIRMLLGLIKPTKGNIKIFEKEFESNKTEILKNIGAMVETPGFYSNLTAKENLTIN
                     AKILGIQKENAIEEVLEIVGLASEKVKLFKNYSLGMKQRLGIARALLHNPELLILDEPT
                     NGLDPIGIKEIRKLIKDLAQSRNITILISSHILSEIEQLVDKVGIIHNGVLLEEIMYED
                     LKKKNRQFISISVSDEEKVACLLETNFGIYDYKIKENGEFKIYSHIDRQQEINRLLVLN
                     NIDVFQMRVIEDNLETYFEDLVGGGTIG"
                     /name="ABC transporter ATP-binding protein"
     gene            24434..25171
                     /locus_tag="FPO40_15200"
     CDS             24434..25171
                     /locus_tag="FPO40_15200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000369394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="QNZ86224.1"
                     /translation="MDNLLRTEFIKLKRSYMFLISILGTCVAPFMVVVASFISMRTKVP
                     TPNIVFKQLFEEVSLYHMLIIGPPLYGVIIAYLFGREYIEDTLKNLLIIPISRESFLVS
                     KIILLFLWIQTLSVIAWLLTLMLGMLLHFQGLSQSLIIDSFFTFVIGGVLLWILSPPII
                     ILSIYFKNYVPTIVLTIIITLINLMTANSEHRGLFPWAAVGDISRGTLPNTYPFLLSLI
                     IIIVTSIFSVIILFSYFKKTDIS"
                     /name="ABC transporter permease"
     ARG             complement(19470..20935)
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="98.36"
                     /coverage="100.0"
     ARG             complement(18472..19370)
                     /name="mphC"
                     /gene="mphC"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="98.66"
                     /coverage="100.0"
     ARG             1492..2009
                     /name="SAT-4"
                     /gene="SAT-4"
                     /gene_name="streptothricin acetyltransferase (SAT)"
                     /tool="rgi"
                     /drug_class="nucleoside antibiotic"
                     /identity="97.16"
                     /coverage="95.56"
     ARG             8289..9133
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="95.37"
                     /coverage="100.0"
     ARG             884..1185
                     /name="aad(6)"
                     /gene="aad(6)"
                     /gene_name="ANT(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="99.0"
                     /coverage="36.23"
     Typing          complement(15338..15485)
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          complement(15544..15719)
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="92.697"
                     /coverage="94.0"
                     /evalue="1.04e-65"
     Typing          complement(15851..16833)
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.593"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          17260..18002
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 aatataattt taacaaaaag gagtcttctg tatgaactat ttcagatata aacaatttaa
       61 caaggatgtt atcactgtag ccgttggcta ctatctaaga tatgcattga gctatcgtga
      121 tatatctgaa atattaagag aacgtggtgt aaacgttcat cattcaacga tctaccgttg
      181 ggttcaagaa tatgccccaa ttttatatca aatttggaag aaaaagcata aaaaagctta
      241 ttacaaatgg cgtattgatg agacgtatat caaaataaaa ggaaaatgga gctatttata
      301 tcgtgccatt gatacagagg gacatacatt agatatttgg ttgcgtaagc aacgagataa
      361 tcattcagca tatgcgttta tcaaacgtct cattaaacaa tttggtaagc ctcaaaaggt
      421 agttacagat caggcacctt caacgaaggc agcaatggct aaaataatta aagcttttaa
      481 acttaaacct gactgtcatt gtacatcgaa atatctgaat aacctcattg agcaagatca
      541 ccgtcatatt aaagtaagaa agacaagata tcaaagtatc aatacggcaa agaatacttt
      601 aaaaggtatt gaatgtattt acgctctata taaaaagaac cgtaggtctc ttcagatcta
      661 cggattttcc ccatgccacg aaattagcat catgctagca agttaaacga acactgacat
      721 gatatattag tgattagcta tattttttac tttgcaacag aaccatcatt tttattaaaa
      781 tactcttttg taaaatcttt ctgctcttca atgtatttaa tttctttacc tctaaatcta
      841 ttatagctat ttgatgatta caataaaatt gatcttacct tattgccctt ggaagagtta
      901 gataattacc taaagggcga taaattaata aaggttctaa ttgataaaga ttgtagaatt
      961 aaaagggaca tagttccgac tgatatagat tatcatgtaa gaaagccaag cgcaagggag
     1021 tatgatgatt gctgcaatga attttggaat gtaacacctt atgttattaa aggattgtgc
     1081 cgtaaggaaa ttttatttgc tattgatcat tttaatcaga ttgttcgcca tgagctgctg
     1141 agaatgatat catggaaggt cggcatcgaa acaggcttta aatgaagtgt aggcaagaac
     1201 tataagttta ttgaaaggta tatatccgag gatttgtggg agaaactttt gtccacctac
     1261 cggatggatt cctatgaaaa catatgggaa gcattatttc tatgccatca attgttcagg
     1321 gcggtatccg gtgaggtggc ggaaaggctt cattatgcct atccggagta tgataggaat
     1381 ataacaaaat ataccaggga catgtataaa aaatacactg gtaaaaccgg ctgcctggat
     1441 agcacatatg ccgctgatat agaagagagg cgggaacagt gattacagaa atgaaagcag
     1501 ggcacctgaa agatatcgat aaacccagcg aaccatttga ggtgataggt aagattatac
     1561 cgaggtatga aaacgagaat tggaccttta cagaattact ctatgaagcg ccatatttaa
     1621 aaagctacca agacgaagag gatgaagagg atgaggaggc agattgcctt gaatatattg
     1681 acaatactga taagataata tatctttact accaagacga taaatgcgtc ggaaaagtta
     1741 aactgcgaaa aaattggaac cggtacgctt atatagaaga tatcgccgta tgtaaggatt
     1801 tcagggggca aggcataggc agcgcgctta tcaatatatc tatagaatgg gcaaagcata
     1861 aaaacttgca tggactaatg cttgaaaccc aggacaataa ccttatagct tgtaaattct
     1921 atcataattg tggtttcaaa atcggctccg tcgatactat gttatacgcc aactttgaaa
     1981 aagctgtttt ctggtattta aggttttaga atgcaaggaa cagtgaattg gagttcgtct
     2041 tgttataatt agcttcttgg ggtatcttta aatactgtag aaaagaggaa ggaaataata
     2101 aatggctaaa atgagaatat caccggaatt gaaaaaactg atcgaaaaat accgctgcgt
     2161 aaaagatacg gaaggaatgt ctcctgctaa ggtatataag ctggtgggag aaaatgaaaa
     2221 cctatattta aaaatgacgg acagccggta taaagggacc acctatgatg tggaacggga
     2281 aaaggacatg atgctatggc tggaaggaaa gctgcctgtt ccaaaggtcc tgcactttga
     2341 acggcatgat ggctggagca atctgctcat gagtgaggcc gatggcgtcc tttgctcgga
     2401 agagtatgaa gatgaacaaa gccctgaaaa gattatcgag ctgtatgcgg agtgcatcag
     2461 gctctttcac tccatcgaca tatcggattg tccctatacg aatagcttag acagccgctt
     2521 agccgaattg gattacttac tgaataacga tctggccgat gtggattgcg aaaactggga
     2581 agaagacact ccatttaaag atccgcgcga gctgtatgat tttttaaaga cggaaaagcc
     2641 cgaagaggaa cttgtctttt cccacggcga cctgggagac agcaacatct ttgtgaaaga
     2701 tggcaaagta agtggcttta ttgatcttgg gagaagcggc agggcggaca agtggtatga
     2761 cattgccttc tgcgtccggt cgatcaggga ggatatcggg gaagaacagt atgtcgagct
     2821 attttttgac ttactgggga tcaagcctga ttgggagaaa ataaaatatt atattttact
     2881 ggatgaattg ttttagtacc tagatttaga tgtctaaaaa gctttaacta caagcttttt
     2941 agacatctaa tcttttctga agtacatccg caactgtcca tactctgatg ttttatatct
     3001 tttctaaaag ttcgctagat agagttctat attagagatg taaagagttt tggtgaagag
     3061 gtttgtgagt atggctttta taaccagggt gcaatgagaa gcactaacag cagctagctt
     3121 aagaacgcat aggatatact ttttatggaa gtcacagagg aggaataaaa tttgaacagg
     3181 attaacagag taacctctat tcttattcag ctgcaatcaa aaaaataatt cctgccaaag
     3241 aaattgcaca gcgatttaat ataagcttaa ggacagttta cagagatatc cggacacttg
     3301 aagaagccgg aataccaatt ggatctgagg ccggaaaagg atattttctt gtagagggct
     3361 tcctacttcc gccggtaatg tttacagcgg cggaagtggg tgcattgatt acagcaggga
     3421 aatttttaaa ttgccatgga gatgaatcat ttataaagga ttttgattca gctatgtata
     3481 aaatcaaatc tattttgaag catggtgaaa aaaactatgc acaggagttg gagaacagta
     3541 ttaacgtgta cagcacatct ggacagaaaa atacattggc ggataacgtt attgcagcaa
     3601 ttcagactgc aatctgcaat aaaagggtaa tatcaattca atatcctgca tcaggagggc
     3661 aagaaccgga aagcagaatg atagagccta tcaggctaag aaatgaatat aggaattttc
     3721 gtgtggatcg gattaaaagc atttgcatag aagaagagct ctgtcaaagc catgatggct
     3781 ctttggaaca aatattaaaa caaatgctgg ttctgttgca aagtaaaaaa atatagctaa
     3841 ccactaattt atcatgtcag tgttcgctta acttgctagc atgatgctaa tttcgtggca
     3901 tggcgaaaat ccgtagatct gaagagacct gcggttcttt ttatatagag cgtaaataca
     3961 ctcaatacct tttaaagtat tctttgctgt attgatactt tgataccttg tctttcttac
     4021 tttaatatga cggtgatctt gctcaatgag gttattcaga tatttcgatg tacaatggca
     4081 gtcaggttta agtttaaaag ctttaattac tttaaccatt gctaccttcg ttgaaggtgc
     4141 ctgatctgta attacctttt gaggtttacc aaattgttta atgagacgtt tgataaacgc
     4201 atatgctgaa tgattatctc gttgcttacg caaccaaata tctaatgtat gtccctctgc
     4261 atcaatggca cgatataaat agctccattt tccttttatt ttgatgtacg tctcatcaat
     4321 acgccatttg taataagctt ttttatgctt tttcttccaa atttgatata aaattggggc
     4381 atattcttga acccaacggt agaccgttga atgatgaacg tttacaccac gttcccttaa
     4441 tatttcagat atatcacgat aactcaatgc atatcttaga tagtagccaa cagctacagt
     4501 gataacatcc ttgttaaatt gtttatatct gaaatagttc atacagaaga ctcctttttg
     4561 ttaaaattat actataaatt caactttgca acagaacctc atttactata tgggcatctc
     4621 tttcattatt aatacaaagc tttgtatctc cgatattagg caaaggtgta aacgaattag
     4681 gtgatactat aggattcaac attatattaa tcgtttcttt aataatgatt atcttcttat
     4741 tttttataaa tcgtagtaaa aatatctcct atgattatat aaaagttcaa agaggtgaag
     4801 ccaatgaata aattagaaaa atggtctttg gtatttatta tttttacatt tctctcttca
     4861 ttagcacttt tatatttcaa atataatttt agttcggtta tgccagtcct aagtctttct
     4921 attttaacta tactaatatt gttgacgagt attattactg tagtttcagt taatgatgaa
     4981 gatacttaaa acgttcatta gtgaaacagg tattatatta aaaaagcgta cgaatttgta
     5041 cgcttttttc ttgtgttatt attaaaatct cataacagga aaatattatg agattttaga
     5101 cgctgtcaga acgtctcttt tacatcgagt gacattgaat caaagtcttt gtatgttaat
     5161 gatatataaa attatttagt agattcatta tagtaagcta gattagttgc tctacttgtt
     5221 tttattctct tttgcctcta atttattgag ataacgataa atagttgtac gtgaaacttg
     5281 ccactgctct gcaattgttt taattggcgt accattatca taaagtgtct taagtaagtt
     5341 taaatcttgt ttatttaatt tttcaggtct acctccatat cggcctctag cacgtgctgc
     5401 aattcgaccg gctgatgatc gctctaaaat taaattacgt tcaaactctg caaatgctgc
     5461 gaataaatga aataataatt gtcctgtaga acttgattta tccatcgtta tattttcttc
     5521 taaactatga aaactcacac ctcgttcgtt aagttcatta actaacgtga ttaaatcctc
     5581 catgttccgt cctagtctat ctaatctcca aacaacaatc gtatctcctg acctcgcaaa
     5641 ttcaattgct ttatctaaac caggtcgctt actttttgaa ccactcatat ggtcattaaa
     5701 tatcttttca caaccatatg tatttaatcg atcctcctgt aaattcaaat tttgtaatcc
     5761 agttgaaact cttgcataac ctattttcaa aatacagacc tcctatatac acctttagtg
     5821 taccataact tgattacgag gtcttttgtg aacatagatt ttttgttggg tttttgaaca
     5881 cataattcta tgtaatacat acttatttag acataaaaag agagtgtaca gaaaatggtt
     5941 attttatgta cactctcatc tttactaata tattttaaat gttattaaca aaactaattt
     6001 aataagagtc aagtatagtt tacatatgta taatgtttga aacatatctc taattacttt
     6061 ttactaatat catttaaaat gtctcgcaat tcttcaattt ctttgttatt taattcttca
     6121 tttttcgcaa aatttagcac taaacttttc atgtcccctc catacagttt attaagaaaa
     6181 gttttagcag ttttcatttt aatatcgtct tctttaatat ttgatgagta aaaataaata
     6241 ttctctgatt tgtatcgttt tataatctct tttttatata gtcttgtgat taatgttcta
     6301 attgttttat cgctaacttc tttatatttt tgaatttcaa ctacaatttc attagctgat
     6361 actgattttt tatcccatat tatattcata acatcccatt cagccataga tatttcaact
     6421 tgcttattgg ccatttaaaa cacccatttc ttttaatatt ttttcactga ttaattcagc
     6481 atttttccca gacgggtttc catctgataa atgtgtagca aaataatact tatcatgatt
     6541 tgtaattacg taacctacaa accacccatt attatacttc ccgtttacta tacctgtacc
     6601 tgttttccca tacagttcat acttttcatt tttcttaatc aataatgaag aagataattg
     6661 attctttgct tttttactaa aatggttatt ttgttccatc atatttttaa aaactattac
     6721 ttgttcaaga ttagatattt tcaaactatc ttccatccaa tagtttttat aacttcccaa
     6781 attttcatta ccataattta attgcttgag ttgagccgca gtatagttct ttggtatttg
     6841 attactaata cgttcgaagt accaattaac tgaattttgc attgctgtat ttaaatcttg
     6901 ttccttattc caagactcga aaggataatg tttatgattc catgacatac gtgaattttt
     6961 atcacttatg atatgacggt caagtccaaa catcgctaaa taaattttat aagttgaatc
     7021 aggagaatat ctttttctac tttctttttc attataaata tagtatttgt ctttcttcat
     7081 gctgtacatg acgaaagatc cactatttga accaaaattt ttactttcat ctaaaatttg
     7141 gtgatcgttc tgtaagggct ttttataatt ataatcagtt atggattgcc ccatcaaaaa
     7201 ctggctttga attactatga gcaaaaaagt aaaaatacaa ataaaaattg gaattaattt
     7261 agactgtttt ttcaaattgg cttcttttat attaattaat cttcttttga gtaatgactt
     7321 tttaccatta aatgaatggc ttaatatatt tttattaaaa aatggaatat ttaatacgga
     7381 gtccataata gattccgcat aagttttaaa ttcatttttg ttaatattat taagaacaaa
     7441 tctatcagct tctacttcat tgtcatgaat tatctttctt tttacaatat gtattaatgg
     7501 attgtaactc ataacaatag agaagatatt aaagataatt aaatgtaaag tatctctatt
     7561 tttagcatga gcatattcat gcagtattat atattttagt cttttatcaa ttacactttt
     7621 aaaatatgaa ctaggaatca aaataatata tttcccatac caaaaagtta ttggagattg
     7681 aatagcctct gcttttcgaa tcacaatatt ttttttatat tgatggttga aaagtatcgt
     7741 atctatttta tttttttcat tttcgtttag ataaagtgac tgtttcttta aatatttaag
     7801 atataataag gctttcaaaa atttaaaact taaaataata actaaaacta tccaaataac
     7861 tgtgcagata ttatcaattg aatcccaatt aaacttatgg atatctgttg tgaactcttg
     7921 aataggtttg gtggtattta tgttatggtt caaatcgtgt gacttacttt caactgtggg
     7981 cgcttgatta ttcacattat taaattttat aaaagagaat ttaattggga taaaaggaat
     8041 taatccagca agcatagtta gataccaaac tttataattt aaactataat taaaatagcg
     8101 ttttaatatg tacctaaaaa atactaacaa tagaaatata aaacaaaagc ttactacgct
     8161 cattattagt aatttagcca ttttgacacc ttctttcaaa tatttataat aaacaattga
     8221 catcaatatt acaattgtaa tattattgat ttataaaaat tacaactgta atatcggagg
     8281 gtttattttg aaaaagttaa tatttttaat tgtaattgct ttagttttaa gtgcatgtaa
     8341 ttcaaacagt tcacatgcca aagagttaaa tgatttagaa aaaaaatata atgctcatat
     8401 tggtgtttat gctttagata ctaaaagtgg taaggaagta aaatttaatt cagataagag
     8461 atttgcctat gcttcgactt caaaagcgat aaatagtgct attttgttag aacaagtacc
     8521 ttataataag ttaaataaaa aaatacatat taacaaagat gatatagttg cttattctcc
     8581 tattttagaa aaatatgtag gaaaagatat cactttaaaa gaacttattg aggcttcaat
     8641 ggcatatagt gataatacag caaacaataa aattataaaa gagatcggtg ggatcaaaaa
     8701 agttaaacaa cgtctaaaag gactaggaga taaagtaaca aatccagtta gatatgagat
     8761 agaattaaat tattattcac caaagagcaa aaaagatact tcaacacctg ctgctttcgg
     8821 taagacttta aataaactta tcgcaaatgg aaaattaagc aaagaaaaca aaaaattctt
     8881 acttgattta atgttaaata ataaaagcgg agatacttta attaaagacg gtgtttcaaa
     8941 agactgtaag gttgctgata aaagtggtca agcaataaca tatgcttcta gaaatgatgt
     9001 tgcttttgtt tatcctaagg gccaatctga acctattgtt ttagtcattt ttacgaataa
     9061 agacaataaa agtgataagc caaatgataa gttgataagt gaaaccgcca agagtgtaat
     9121 gaaggaattt taatattcta aatgcataat aaatactgat atcatcttat agtttgtatt
     9181 atcgttgaca tgtataattt tgatatcaaa aactgatttt ccctctatta ttttcgatat
     9241 ttattttctt aattctcttt aacaaactag aaatattgta tatacaaaaa atcataaata
     9301 atagatgaat agtttaatta taggtattca tcaatcgaaa aagcaacgta tcttatttaa
     9361 agtgcgttgc ttttttctca tttataaggt taaataattc tcatatatca agcaaagtga
     9421 caatagcatt ttacaagtat tttttattgt tcgattaggg taaacctaaa taatacataa
     9481 attatattac aatatgttta ttatagaggc taaagtatct tagaaatttg gatagtaggt
     9541 ttttcgggaa taaaagtata gttggcttta atatataatt aagctaagct atcatttata
     9601 tttactcgat tataattcgc acttcaactt ttttataacg taaaaattaa aacgtagttt
     9661 tatttatctt tagtaatatc tttttaaaca ctacagtttc ttcattagtt aaattagcga
     9721 agtaatgatt attaagttga taggctttct tttctaatgt tggccataag tcttttgctt
     9781 tatttgtact gtttattagc acagttcttc tattttcatt atcagtttga cgtgttatta
     9841 gatccttttt ggacatctta tctaatattc cagatattgt tgaaggttct aaatttaaag
     9901 tattaccaat cgctttaggt gtattcaaat tactattaat caagcaattc aaaacaccat
     9961 attctgctgg agtaatatta tagggactta ataaactttt aaaatgttta aaaactctat
    10021 tctgagaagt actcaacaaa taatttatac aattatctaa ttccacaact aaaacctctc
    10081 ttaaatcatt agtattgact cgcttatcat atcatgataa gttttgtagg aaaatagttt
    10141 tgcaacaaaa acatacttct acaaaacaat tgtgaaagaa ggctaataaa tgttcaatgc
    10201 ggtagtagtg agaaaaagtg catcaaatgt tagttataaa gtagaaaaag ttgatgaatc
    10261 tcatttatcg aagggtgatg tattagtaaa agtggtatac tcttcaataa attataagga
    10321 tatgctagct ttacaatata aaggcggtgt aattagagat tatcctatga ttcctggtat
    10381 agattttgca ggtattgttg aatcaagttc gaatgataag tttaaagaag gcgataatgt
    10441 attagttact ggttatgatg ttggcgtgac acatacaggt ggattttcag aatatgcaca
    10501 agtgcctgga gagtggattg ttcctattcc ccaagaaatg tctattaaag agtctatggt
    10561 atatggcaca gccggtttta cggcagcatt atcaattttt gaactagaaa aatatggaat
    10621 gaatatcaaa tcacaacctg aaattttagt gtctggggct acaggtggtg tgggcagtgt
    10681 tgctatacaa attttacata aaattggata tgaaaatatc actgctatcg taagaaaaga
    10741 aaagcaaata gaaatcgcaa aaaaattagg tgcaaaacaa gtaataataa ttgaagatga
    10801 taataaaccg cttaaaaaag gtatttttga ttatttctta gatacagtgg ggagtaatgt
    10861 aacattatac ggtttaaaac gtctaaatta tcaaggtgtt gctactgtat gtggaaatgt
    10921 agcaggaaat tcacttaacg ctaatatatt accgtttatt cttagaggta ttaaattaat
    10981 tggcattgat tctgtatatg ttgatcataa tatccgtgaa gatatatgga gtaagttagc
    11041 aaatgaatgg aatataggaa attcacttct atacaatgaa attggatttg aagaattcta
    11101 taaaacgata gatcagcttt taaaaggaca acatttagga agaactattt taaaagtata
    11161 agtgtgagta ttcattaata catttactat taattcaatc attttgcatt tctctactaa
    11221 ccagtgttat aatttatata acgaaaatga ttaacaatta atgcaccaat ccccacacta
    11281 ttgcagtagt gtggggattt tttcgatgct ggcttataaa gtcgcctatt aattatttgt
    11341 tgcgtttact aagccaataa gtataatacg caacagcaca gccactgatg actggtgcta
    11401 tgatgtgaac gaaaatgatt agcaaagtaa tgcacctcct ctcttcgtca attgacgcct
    11461 gagagatagg cgactctatt attataccat ctgtgaatat acaagcatat ctacttccga
    11521 taagtcgtct tatgttatat aactttgttt tttatagtat caagacaaga agaaactcgt
    11581 ttcaaaaacc ctcatgattt ttagagaaaa actctcttat ttcatcgtct ttaataaaat
    11641 aatatgccat ctttccatct ttataaaaat caagtacctc atttttatat aaaagcctta
    11701 aatgatgtga agttgaagca acactcattt tcaatatcaa agaaatatca caaacacaca
    11761 actcatcttc tttaatcaaa gataatatga ttttcaattt cttctcatca caaatttttt
    11821 ctaaaatgtt aagtaatttc ttagatttat catcttctaa aaaacttaaa gcattgttaa
    11881 ctttatcctc atgtacacag atcacatcac aagtattttc ataactcata taaaatcaca
    11941 ccctaaatta aaatataaat cctaaaattg tttgaatagt gtcattttca ataataataa
    12001 ataaacctaa agctatataa ataatagcca taatccaacg actaaatttc tcaacaattt
    12061 ctccaattcc tggaatatta gctaattttt gtgcagtaaa caccaagaag aaaattaaaa
    12121 ttaaaaagac aaacagagta agtaataaat tagtaacact taatgtcaca aaatacggaa
    12181 caaataaacc aatattatcg gcgccacaac ttgctatcgt aacaattgca accgtaccaa
    12241 ctaatttaga caatcctttt tcattcaatt cttttttagc tctcttttct ccttcacaat
    12301 catcataaat agccacttta attccaagat aaattggtat taaacccaat aaacctaata
    12361 tccacttttc tggaacataa tttaatacaa aagctaaaaa caaactaact aatattaaaa
    12421 taatagaccc taaatattga ccaacataaa tatctctata ttcttttcta gtctttgctc
    12481 tagcaaaaaa tattaataaa attactaata aatcaactgc tgtagcaata taaagaacag
    12541 cagcagcaac aaccgtttga atcataatac acctcattca aaaatatttt tgaatgtatt
    12601 ataacttata tttttaaata atcataggtg ctttattcca attgctttat tgacgttgag
    12661 cctcggaacc cttaacaatc ccaaaacttg tcgaatggtc ggcttaatag ctcacgctat
    12721 gccgacattc gtctgcaagt ttagttaagg gttcttctca acatcaataa attttttcgg
    12781 cataaatgcg tgtctatgcg tagacatgga gacacttcag aattatggag tgattacatg
    12841 agtttaacta tttttcttta ttcagtttta ggaagtttat tagcaaatta tatctacgaa
    12901 aaatcttcaa aataaataac tttttcggtt ctattttgta cactttatct acctggtaga
    12961 cctaattgtt attgctttac aggtctaaaa ttcgtcgtta taatctagtt aaatcccgta
    13021 agggcgcact tatacgtcgg ataaatcgac atgtgcaaaa acgtaatcga ccttcgtcga
    13081 tttttttatt tcaaaattaa agaaacggct tgagatattc cgagcagtta taaaaattaa
    13141 tttgcgttga atattgctac tacattcttg aaaaagtgat gtagatttat agcccataac
    13201 ttttttgaat tacatcgacg atacggcgtc gaaagaaaaa taaatagacc gtatgaaaga
    13261 aaaagctacc tcactttatc tggggtagct tttatttttt atgcccttat tttgaatttt
    13321 aagagggcat tttaaagatt taggggtgat tcatatagtt ttatatctaa aacttatata
    13381 tgcttttaaa acgcaaatat gagccaaata aatatatgct attttcaaaa acaaaaattt
    13441 gagcaaaaac aataactatt tttagacact gcccatttac atgcaaatta aaaattagca
    13501 taaaattctt taaaacttcc ccacgttttt ctaaattcct gtagggcgtt tttatcaaaa
    13561 atcaagacaa gaagaaactc gttcacactc gtttcaaaaa aacaagaaat ctaatctata
    13621 cacctaccgt tttccaaccc cctcaaagca tacaaattaa aaacaaaatt attcataatc
    13681 ttactttctt ttaacaaaaa cataaaaacc ataaatagac aaattaacta tcaaaggcaa
    13741 taaacagtat aaaaaaacca cgaataaatc ttcatcaaca tctaaaataa aaaagaataa
    13801 aacaattaac aaaatactaa ttaacaaacc taaaagtggc aaacttttta tatatttttc
    13861 taaattttca ttcataaaat agactccttt caaaaatatg tttataaata tattaaaata
    13921 aatattgatt ttataaagcg cttacttata caattaaaat atcttattat cttggaggta
    13981 tcaaatgaaa attataaaat tattttcaat aatttccttg ttcctactgg tatttagcgc
    14041 gaatttttct aatgcttacg caaatgaaga acaaaaaagt tctttactag aaaatcaaaa
    14101 agaaaaattg aaaagcaaaa acatcgaagt atcacaaatg accaagaaag aaataagttt
    14161 tctagaacaa ttgcaaaata aaaatgaaga tatgcaaaaa ttcgaaaagc aaatgaaaaa
    14221 agaaggattt aaaaaaataa agctagaaga caaaaattct aaattaaaat atctagctac
    14281 agaagcaaat gataaaaatg catatggcta catagctaat aacgcttata aaaatgaaaa
    14341 aacaaaagaa attgtagttt ctgaaacaat atatgataac tacaacaaaa aaatcacaaa
    14401 attcattgcc gaaaaaagaa gtatgactga aaacaaagag ggaaaaatac ttattaacaa
    14461 aaattacgtt gaatataagg ctgaaaaagt tgataaaaac agaccggtaa catatgcagg
    14521 attcaaatgg aacggcaaag cattcgcttg tagtatggct ggactttatg catgtgctca
    14581 ctactgtgga gtatgggcaa tcgtaaatcc aatagccggc ggtgtatgtg aagcagtttg
    14641 cggaactgca tttgcagctg gatgctctgt aggttgattt tattccaatt gttttattga
    14701 cgttgagcct cggaaccctt aacaatccca aaacttgtcg aatggtcggc ttaatagctc
    14761 acgctatgcc gacattcgtc tgcaagttta gttaagggtt cttctcaaca tcaataaatt
    14821 ttttcggcat aaatacgatg ttccttattt atcctcataa aaaacaatag ctgaaatata
    14881 taaccaatta ctgtgtgttt gaatttctaa tacatgaata tcattcttta aaaacctatt
    14941 aacttgttta tctaattgac gatgagtaaa agtagcgaaa gttttaatct tcatgatatc
    15001 tctcctttta taaaaatagc aatccttatt acaatattaa acacttttat tttggatttt
    15061 aagaggcatt ttgaagactt agaggcaaat catataggtt ttgtacttaa aaatctatac
    15121 agtctcttaa aacgcaaata tgagccaaat aaatatatgc taatttcaca aacaaaaatt
    15181 tcagcaaaat cagtgactaa ttttttagat actgcccatt tacatgcaaa tttaaaaatt
    15241 agcataaaat actttaaaac ttccccatgt ttttctaaat tcctgcaggg cttttcttat
    15301 caaaaactta gaaattttaa tttaactcta aaatctccgt aagagcataa gggaaatttg
    15361 ctatcattca aaaatgatag atctggcaag gccagacatt ccaagggttt taagttattt
    15421 taaagtgata tcatacaaag ctgtagtgtc acacttttgt gacactacat acagcatttg
    15481 tcacaaaaat aagacagcac ttttttacag aaaaacaata aaaaaagaca tcagttatca
    15541 ctaatgtctt aaataataat tttgcttttc gaaattccaa attgcggtaa ttgaatgtgc
    15601 tttttttctt cgtctgtcgt tttatcttca tcacttgtat taatcaaatt accatcttcg
    15661 gcatcgtcta agtttaaaat tttatgcttt tgtttaagca atccaccata acttaacata
    15721 cgttttcgat acaaaccttt ttctaaatca cttacaattt cttgattttt ttcgtcgtca
    15781 tcagttaaaa agtcagatga tttaacggaa tattttgatg tctcttcgag tgttataaaa
    15841 tcatttgaat tattgattaa agatattata ttgtttcatg tttttacggc gcatataaag
    15901 ggcatgtgtt tcttcaagtt cagttagaat tgtttgcatt aaataagctt gcattgactt
    15961 gattgtttcc ttttggcctt taactcccct atcatgtata gcttttttaa gtctttttaa
    16021 agaagttaat atttcatcct caatgtcctc taacatgtaa tgcatatctt catgccttga
    16081 attaaatgat ttttttgctt taagaataac agcctttatg atttctaaat ctctataatc
    16141 atattttaat aaataattag ttagttgttc tgggaattct tgcaatagca tttctttatc
    16201 atcaaaatta tgtgtaaatt gatttgaatg atttgaatga ttactaattt catttttgta
    16261 ctttatatca ttcaagtcat tcatatcatt attctcagta tcattaaagt caatgtcatt
    16321 aaagtcagta tcattagtgt tcgattttcg aacttctgga cgttcgattt tcgaacttct
    16381 ggacgttcga ttttcgaact tctggacgtt cgattttcga acttccttct cgccgtaagg
    16441 ttcaacatcg ttttcttctt tttctatttt gtaaatatca cgttctgtga caataggttt
    16501 cattaaatat agaatatttg gtttatttaa accacgtcgt ttttgaatga gtagaccatc
    16561 gttttctaac ccttttttta tttttgttaa cttttctttt ttacaattta agatttccat
    16621 tagcttttca tttgaataaa caaagtaaat gttaccatct tcatcaaccc agctattttt
    16681 aatagataaa tttaagcgat cacgtaagat agcataggct attttcatat cattagttag
    16741 atttttataa ttttcactgg taaagaatac tttagggatt tgataaaatc tttctttgta
    16801 attttcttgc actgtaaaat attgattttg catgacaaaa aacctctttc catattttag
    16861 tttggtaaga ggtaataaaa cgtttttatt tagctttaca tttatttaat gatttaggtg
    16921 cttgcactaa gatattattc attatataat acaagtatcg aaaattatat aaataaacag
    16981 tttctaaacg ttttattacc aaaccccgac tattaccagt agttggggtt tttgttatat
    17041 taagtttatt atagcacttt aaataaactt ataaaaggga aaatatagct ttatcaaggg
    17101 tttataaacc cttgataaat atcataaacc tttcataaac ccttgataaa aaggttgatg
    17161 gatgtttatt tttatttatt aatcacttta ttattaagca ttataagatt ataatatttt
    17221 atcaagggtt tataaacatt ttataaaggg ttgatgatat gaaaagtgtg aaaaagttga
    17281 gtgaagaatt aggggttagt aagcaaacga tttttaataa tattaagcga ttgaatatag
    17341 agacaataaa acaggaaaac acttcgttta ttaaagaaga taccgatata gaaaaaatca
    17401 ttcaaagagt aaatgaaaat aaaaagaaat atggttttga aagtactact gaagacaaac
    17461 aaaaaaaagg gtcggataat attaattttg aatcgaaaag cgatgctcaa atagtagaaa
    17521 tccttaaaaa tcagattgat actttaaata atcaaattga aaaacaagaa agtcgtcatg
    17581 aaacaacaat tgaattttac agaaaagagt tgcaagaaag atcaaaattg cttgaaaatc
    17641 agcaagttct ggcattagag agtaataaaa agattcaaaa attagaaaat caattagaaa
    17701 aagaaaaaca ccttaattat ccctttgata catctactaa cactagacaa aacgttgatg
    17761 cacaagaaaa aacatatact actaatcctg taaatattaa cagagatcag gaagaaacta
    17821 aagaaacaga gattcaatat aaggatatat ctggaagtca aagcgacgaa agtacacaag
    17881 gtgaagaagc aaaaaaagaa gacgttccag ctaatctaaa tgacaatgat agtgatatag
    17941 aagaaaagag tgaagaaacg gaacctaaaa aggggttttg gagtcgtttg tttggtagct
    18001 aaaataattg attaggcact aaaagttata aaattttagt gtcttttata tagtgagaac
    18061 ttctggtaat catcgattat gtaaactaaa gtatttcaaa taattaactg tattaatact
    18121 ctcatcatga ttgcgttata aacgttcatt tgaaggtcat ctctatcata aatatttaaa
    18181 ttaactaaaa attttaatca tctgtttaat acttatgaaa tgtatttacg gtaggtatta
    18241 aaattgatga aatttatata agtgctttca atgaaaatga ccgtttattt atcctcctga
    18301 tttaaggagt tagaaatttc gaaaacgatt ctttccattt gttgcatttg ttccatgtcc
    18361 agatatttaa tacattatag aaaaccaaag accatcacta attaaacgca gttttaaaat
    18421 ttcatcagga ttgccttcgt ctttaaaatg ggcctctttt aatataagtt ctactctttc
    18481 atacctaact ctttcaatgc catcgtttca tacgccgatt ctcctgattc catagcaaac
    18541 tcagcgataa acattgggaa tactgcattg agttctatta tatgctcttt cattcgtggc
    18601 catatttcac ctccagcttt accgtatgct gttataagtt gctctaatcc ttcgtcgtcg
    18661 aatacacgat ggtgtcctat aaagtccatt gatgggtcgg agtgggttgc ttcagtccag
    18721 tctatgagac ctgtgacgtt tgcttggtta tctaccatta tatgtcctgg atgtaagtcc
    18781 ccatgtatca tggtcgcatg tcgaggccat agttcgtcgt tttctaacca ttgtttccat
    18841 ctgttccata attcatctga tacgccataa gtttctttaa ctttattcat tcttctttga
    18901 aagtcatttt ttatttcttg tatggttttg atatttatat gctgaacgtt aatgttttct
    18961 tctggtatgt tgtgtaaatc tacgagtgtt tcagctaatg tgttaataaa gttttctggt
    19021 aatggtttgt gttcaatttc ccatacataa ttttgtattt ctggatctat tgtggctgcg
    19081 ggtttacctg taagttttgg gtaagcaata aggtcttttg catgtacttt ccacttcggt
    19141 atttcaaatg aaacattctt ctgtaagaag tctaccgttt gtttttcggg ttttgttcgt
    19201 ttataaacgt caggtcttct tggtagtctc aaaacccatt ctactccatg tttatctttt
    19261 ccaaatgcaa cttgaaaatc aagtcccgat tcattcaatg agattgtttg aggttggatg
    19321 tgtaattgat atttttctgc acatttaata atttcattat gtcgagtcat tttattggat
    19381 ccttatttct attatatttt tcttgtgaac gtatttttta tattgatata aatgaaccta
    19441 atattcaata taaattagtg tatagttttt aagttatatc atgaagagat tgtcctgtta
    19501 attcccattt tttatctgat acatgtttaa caaaccttgt atcatgtgat gtaaacaaaa
    19561 tgattccagg atatttattc ataaacattt ctaatgcttc taatgtttta atatctaaaa
    19621 aattagttgg ttcatccaaa attaacatat tcgctttcgt tgaaaataat actgctaacg
    19681 ataatttcgt tctttcccca ccactcaaaa cattacaaga acgatcaagt gcttcattta
    19741 aacccaagtt atttaaaata gctctactga atgattctga tgaatccgtt tcatccatta
    19801 aatattgcaa taatgaaacg tcacgcatgt cttcataagc aagttgacga tagtatgcca
    19861 tttgcacttt aggagaacaa tcaattccct ctatttggtg gtaaatagct tcaagtaaag
    19921 ttgtcttacc tacaccattt gcacctacga gcgctatatt tttgccatat ggtatttgga
    19981 atcgtacttg tgttagcagt ttttgacttc ctttaaccaa tgttagattt tgtgcaatga
    20041 ttggataatt attatggata tcataaattt tattttgtgg gaaattgaat tcatgataac
    20101 tttgtggttt ttcaacttct tccaaatgtt ccattctttt ttcaatatgc ttagcttgtt
    20161 tttgagcagc cttctcaacc gtgccttttt gttttgatgc acttaaacga tctggtgcta
    20221 tacttttgtt tttttgtttt gatgatgctt gtgccatttg ttgcgcttga tttcgtttag
    20281 ctttactggc ttgggacaat ctttgttttt cacttatata ctgttcatat tgacgttgtt
    20341 gttctaactg ttcttgttca tattgatttt gatactgtgt gtaattacct ttaaacactc
    20401 ttattgtgcc atcttcttgt atatcccaaa ttgtgtcagc aatttggtct ataagtgctc
    20461 tatcatgact tactataatt aaagtaccat agtaatattt taaaatattt ttcagataat
    20521 ctttaccaat tttatccaag tgatttgtag gttcatctaa aagtaatatc ggactataat
    20581 ttgatatgac attagctaat ttatattttg ctttttcacc accactcata ctgtcggttg
    20641 tatgcatagg tatatggagt tcactcatta aactaccgtc taacgtgtta aaatcatttt
    20701 ccacatccat gttaagctgt tcaaaatatt gaatttcgcc aaccgtttca actgttccag
    20761 attctggttt tgttttttga gcaatcatat ttagtaatgt ggttttgcca gtaccattac
    20821 ccccaataag tgctattttt tcaaattggt aagcgtaaag atgaccgatg ttaagtgatc
    20881 gtaaatctgt caatttatga ttgatttggt taaatttaat tgtatattgt tccatattta
    20941 tacactcctt gtatatttaa aggacgtgta cgcaaaaaaa tgagacaggc tactcccgtc
    21001 tcattcacat tacactttca aacacttaaa aatttattat gatgttttag tatttgaaag
    21061 cgtttattat tcctatcgaa ggataaaaaa tgacataagt catcctatga gtgtgtattg
    21121 cggacaagcc tttttgaatt aatttagttt tgtattcaaa aaggtttatt tgagtctcat
    21181 agaagctgtc attttaatcc tccttcatcg ataaaatagt aatgttaata taacattttg
    21241 ttggtttttt tacaatatat ctctaagtag aaagattata taacaaaagt ataaaaatac
    21301 aattttagat tgattataca tctccttaat ttagagtgta ctcataaaat acggttctgt
    21361 tgcaaagttg aatttataat ataattttaa caaaaaggag tcttctgtat gaactatttc
    21421 agatataaac aatttaacaa ggatgttatc actgtagccg ttggctacta tctaagatat
    21481 gcattgagct atcgtgatat atctgaaata ttaagagaac gtggtgtaaa cgttcatcat
    21541 tcaacgatct accgttgggt tcaagaatat gccccaattt tatatcaaat ttggaagaaa
    21601 aagcataaaa aagcttatta caaatggcgt attgatgaga cgtatatcaa aataaaagga
    21661 aaatggagct atttatatcg tgccattgat acagagggac atacattaga tatttggttg
    21721 cgtaagcaac gagataatca ttcagcatat gcgtttatca aacgtctcat taaacaattt
    21781 ggtaagcctc aaaaggtagt tacagatcag gcaccttcaa cgaaggcagc aatggctaaa
    21841 ataattaaag cttttaaact taaacctgac tgtcattgta catcgaaata tctgaataac
    21901 ctcattgagc aagatcaccg tcatattaaa gtaagaaaga caagatatca aagtatcaat
    21961 acggcaaaga atactttaaa aggtattgaa tgtatttacg ctctatataa aaagaaccgt
    22021 aggtctcttc agatctacgg attttcccca tgccacgaaa ttagcatcat gctagcaagt
    22081 taaacgaaca ctgacatgat atattagtga ttagctatat tttttacttt gcaacagaac
    22141 cagccattta atatgactgt tacaattact aagattcaag cactattacg ccgcacgtat
    22201 gatttcacca ctcaagttaa taatttaaca gtagatgatt gcgagttact acttgatgca
    22261 gcaaagctta aatttaatga agaaaccata gacctgacac acactgaatt gcaaatcatg
    22321 catagcttat tccagaacaa gggcaaattc gtcagtcgta atgcgttaat cgaaaaatgc
    22381 tgggaatcag aacacttcat tgatgacaat acgcttgctg tcaacattac acgtttacgc
    22441 aaaaagctac aaaaactagg acttacagat tttatcgaaa cgaagaaaaa tgtcggatat
    22501 cgtgtaggtg acgtatgaat ttcttgaaat caatccaacg tgaaatttat attgtcatcc
    22561 ttacttgtgc tttattctac tttatattat tcatgtataa tgtgccgatg caagcatata
    22621 tgattggtct aggtattgta ttgtttgttt caatgattta ctggggtatc cattacatga
    22681 actttaaaaa agaataaaca ctacaggaac agaacgaaga tttaagaatc gaaaaccata
    22741 aacttcgtaa tgactttatt aactaccaaa gtgagttaga gtcatatttt ttaatgtggg
    22801 tgcatcaaat caagacaccg attacagcat caaagttact gcttgaagat cctgatgaac
    22861 acgtgatttc taacgtgcgt aatgaagtct tacaaattga taattacacg aatcttgcac
    22921 tgaactattt gaaactcatg aaccaaaaga catacatggt ctttatggaa gtgagtgtag
    22981 atgaattaat tcgaccactg attaaacgtt atgcgataca gtttattcat catcaaacaa
    23041 agttgcatta tgagaaaagt gaagcggtta tattaacaga tgccaaatgg gcatcaatta
    23101 tgattgagca aatattaaac aatgcattaa aatatgcacg tggcaaagat gtgtggatta
    23161 cgtttgacga aaatacaaag aaattatcaa tccgagataa cggtatcggc attaatgcga
    23221 gtgatttacc gaaaatcttt gataaaggtt tctcgggcta taacggtaga ataagtgaga
    23281 aatcaagcgg tattggttta tatattgtca gcacaatctc aaagcgctta ggccataaag
    23341 taagtgctac atctacatta aacgatggtt caatattcac cattcaattt aaataactcc
    23401 aatctttcat ttttgtaaga ttagcggctg tttttgtaag aatagataaa ggcagccttt
    23461 tctaatcgcg cgtaagataa aggtaacaac aaactaagaa aggtgccaga ggtgaaaaat
    23521 ttgaataata taattgaaat aaataactta acaaagcaat atggaagtca gatagcagtt
    23581 aataatttga gtataactgt tgaaagtgga caaatttatg gttttttagg aagaaatggt
    23641 gcaggcaaaa caactactat aagaatgctt ttaggcttaa ttaaacctac gaaaggtaat
    23701 attaaaatat ttgaaaaaga gttcgaaagt aataaaactg aaattttaaa aaatattggt
    23761 gctatggttg aaacgccagg tttttatagt aatttgacag ctaaagagaa cttaactata
    23821 aatgctaaaa tattaggtat acaaaaagaa aatgcaattg aagaagtgtt agaaatagta
    23881 ggactagctt ctgaaaaagt aaaattgttt aaaaattatt ctttaggtat gaagcaacgt
    23941 ttagggattg cgagagcttt attgcacaat cccgaattat tgatacttga tgagccgacg
    24001 aatggattag atcctattgg cataaaagaa attagaaagt tgattaagga tctggctcaa
    24061 tctagaaata taaccatttt aatttcaagt catatattgt cagaaataga gcagttagta
    24121 gacaaggtgg gtattattca taacggagtt ttgttagaag aaattatgta tgaagattta
    24181 aaaaaaaaga acagacaatt tataagtata tcagtatcag atgaagaaaa agttgcatgt
    24241 ttgttggaaa ctaacttcgg aatttatgac tataaaatta aagaaaatgg cgaatttaaa
    24301 atttattcac atattgatag acaacaagaa attaatagat tattagtatt aaacaatatt
    24361 gatgttttcc agatgagagt gatagaagat aatctagaaa cttatttcga agacttagta
    24421 ggaggtggca caattggata atctactccg tacagaattt attaagttaa aaagatcata
    24481 tatgtttcta ataagtattt taggtacatg cgtagcacct tttatggtgg ttgtagcttc
    24541 ttttattagt atgcggacga aagtaccgac tcctaatatt gtatttaaac agttatttga
    24601 agaagtcagt ttatatcata tgctaattat tggacctcct ctatatgggg ttataatagc
    24661 ctatttgttt ggaagagaat atatagaaga tactttaaaa aacttattaa ttatacctat
    24721 atctagagaa agttttttag taagtaaaat aatattatta ttcttgtgga ttcaaacact
    24781 atctgttatt gcatggttgc taactttaat gctaggtatg ctattgcatt ttcaagggtt
    24841 aagccagagt ttaataattg attcattctt tacatttgtt attggcggag tgttattatg
    24901 gatattatct ccaccaataa ttattttgtc gatatatttt aaaaattatg ttcccacaat
    24961 tgttttaacc ataataatta ctttgataaa tttaatgact gctaattctg aacatagagg
    25021 attatttcct tgggctgcag ttggagacat atctagagga acattaccta atacttatcc
    25081 atttctatta tctttaatta tcataattgt tacatctata ttcagtgtaa ttatattatt
    25141 ctcatacttt aaaaaaactg atataagtta aaaggaggag aaaaatgggt tttatagagc
    25201 agattaaagc atttatttta ggtgtagttg aagggttgac agaatttgct ccagtatcat
    25261 caacaggtca tatgattatt gttgatgata tgtggttaaa cactgctgac gatttaggaa
    25321 gtgcgtctgc aactactttt aaggtggtaa tacagttagg aggttctgtt gcaaagttga
    25381 atttat
//
