LOCUS       CP049552               22612 bp    DNA     circular BCT 24-SEP-2020
DEFINITION  Staphylococcus aureus strain pt192 plasmid pER05238.3A.1, complete
            sequence.
ACCESSION   CP049552
VERSION     CP049552.1
DBLINK      BioProject: PRJNA470993
            BioSample: SAMN12331009
KEYWORDS    .
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 22612)
  AUTHORS   Caban,A.B., Pak,T., Kumaresh,A., Dupper,A., Chacko,K.,
            Sullivan,M.J., Altman,D.R. and van Bakel,H.
  TITLE     PathoSPOT genomic surveillance reveals prolonged under the radar
            outbreaks of nosocomial methicillin resistant S. aureus bloodstream
            infections
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 22612)
  AUTHORS   Caban,A.B., Pak,T., Kumaresh,A., Dupper,A., Chacko,K.,
            Sullivan,M.J., Altman,D.R. and van Bakel,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-FEB-2020) Genetics and Genomic Sciences, Icahn School
            of Medicine, One Gustave L. Levy Place Box 1498, New York, NY 10029,
            USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.3.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 174.743910374463x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/28/2020 16:46:46
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 4.11
            Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region
            Genes (total)                     :: 3,010
            CDSs (total)                      :: 2,928
            Genes (coding)                    :: 2,846
            CDSs (with protein)               :: 2,846
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 47 of 82
            Pseudo Genes (incomplete)         :: 25 of 82
            Pseudo Genes (internal stop)      :: 22 of 82
            Pseudo Genes (multiple problems)  :: 12 of 82
            ##Genome-Annotation-Data-END##
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..22612
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="pt192"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="pER05238.3A.1"
                     /geo_loc_name="USA:New York City"
                     /lat_lon="40.7903114 N 73.9528738 W"
                     /collection_date="2016"
                     /collected_by="Mount Sinai Hospital"
     gene            145..888
                     /locus_tag="FPO55_14700"
     CDS             145..888
                     /locus_tag="FPO55_14700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002508633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="QNZ59064.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     gene            complement(1115..1300)
                     /locus_tag="FPO55_14705"
     CDS             complement(1115..1300)
                     /locus_tag="FPO55_14705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016912974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="QNZ59065.1"
                     /translation="MKNRIREYRKQKGISQETLSKELKVSRQTINAIENNKYDPTLTLA
                     FKLARLFDTTVDELFS"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(1305..1643)
                     /locus_tag="FPO55_14710"
     CDS             complement(1305..1643)
                     /locus_tag="FPO55_14710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QNZ59066.1"
                     /translation="MNLIPFIIILIFSCLWTAITNKYLPSETLDKKGQQDRYDERQRKM
                     FIEILAKSFIWIVYCMLFTLVLKFTGLSPSIEGSWFSQYPEIFFIIVALFLMLFNYYTT
                     NKKYTSKG"
                     /name="hypothetical protein"
     gene            complement(1889..2497)
                     /locus_tag="FPO55_14715"
     CDS             complement(1889..2497)
                     /locus_tag="FPO55_14715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="QNZ59067.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEIIETVNYLKEKDVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRV
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDKGLS"
                     /name="recombinase family protein"
     gene            complement(2983..3882)
                     /gene="mph(C)"
                     /locus_tag="FPO55_14720"
     ARG             complement(2987..3882)
                     /name="mph(C)"
                     /gene="mph(C)"
                     /gene_name="Mph(C) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(3981..5447)
                     /gene="msr(A)"
                     /locus_tag="FPO55_14725"
     ARG             complement(3985..5447)
                     /name="msr(A)"
                     /gene="msr(A)"
                     /gene_name="ABC-F type ribosomal protection protein Msr(A)"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     gene            5921..6595
                     /locus_tag="FPO55_14730"
     CDS             5921..6595
                     /locus_tag="FPO55_14730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="QNZ59070.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            6653..7030
                     /locus_tag="FPO55_14735"
                     /pseudo=""
     CDS             6653..7030
                     /locus_tag="FPO55_14735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866106.1"
                     /note="incomplete; partial on complete genome; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /name="response regulator transcription factor"
     gene            7027..7908
                     /locus_tag="FPO55_14740"
                     /pseudo=""
     CDS             7027..7908
                     /locus_tag="FPO55_14740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501406.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /name="HAMP domain-containing histidine kinase"
     gene            8024..8953
                     /locus_tag="FPO55_14745"
     CDS             8024..8953
                     /locus_tag="FPO55_14745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000074567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="QNZ59071.1"
                     /translation="MKNLNNIIEINNLTKQYGSQIAVNNLSITVESGQIYGFLGRNGAG
                     KTTTIRMLLGLIKPTKGNIKIFEKEFESNKTEILKNIGAMVETPGFYSNLTAKENLTIN
                     AKILGIQKENAIEEVLEIVGLASEKVKLFKNYSLGMKQRLGIARALLHNPELLILDEPT
                     NGLDPIGIKEIRKLIKDLAQSRNITILISSHILSEIEQLVDKVGIIHNGVLLEEIMYED
                     LKKKNRQFISISVSDEEKVACLLETNFGIYDYKIKENGEFKIYSHIDRQQEINRLLVLN
                     NIDVFQMRVIEDNLETYFEDLVGGGTIG"
                     /name="ABC transporter ATP-binding protein"
     gene            8946..9683
                     /locus_tag="FPO55_14750"
     CDS             8946..9683
                     /locus_tag="FPO55_14750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000369394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="QNZ59072.1"
                     /translation="MDNLLRTEFIKLKRSYMFLISILGTCVAPFMVVVASFISMRTKVP
                     TPNIVFKQLFEEVSLYHMLIIGPPLYGVIIAYLFGREYIEDTLKNLLIIPISRESFLVS
                     KIILLFLWIQTLSVIAWLLTLMLGMLLHFQGLSQSLIIDSFFTFVIGGVLLWILSPPII
                     ILSIYFKNYVPTIVLTIIITLINLMTANSEHRGLFPWAAVGDISRGTLPNTYPFLLSLI
                     IIIVTSIFSVIILFSYFKKTDIS"
                     /name="ABC transporter permease"
     gene            9697..9900
                     /locus_tag="FPO55_14755"
     CDS             9697..9900
                     /locus_tag="FPO55_14755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001627151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP kinase"
                     /protein_id="QNZ59073.1"
                     /translation="MGFIEQIKAFILGVVEGLTEFAPVSSTGHMIIVDDMWLNTADDLG
                     SASATTFKVVIQLGGSVAKLNL"
                     /name="UDP kinase"
     gene            9930..10034
                     /locus_tag="FPO55_14760"
                     /pseudo=""
     CDS             9930..10034
                     /locus_tag="FPO55_14760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015063485.1"
                     /note="incomplete; partial on complete genome; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /name="IS6 family transposase"
     gene            10299..10484
                     /locus_tag="FPO55_14765"
     CDS             10299..10484
                     /locus_tag="FPO55_14765"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QNZ59074.1"
                     /translation="MNKLEKWSLVFIIFTFLSSLALLYFKYNFSSVMPVLSLSILTILI
                     LLTSIITVVSVNDEDT"
                     /name="hypothetical protein"
     gene            complement(10707..11285)
                     /locus_tag="FPO55_14770"
     CDS             complement(10707..11285)
                     /locus_tag="FPO55_14770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="QNZ59075.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEAKENKNK"
                     /name="recombinase family protein"
     gene            complement(11549..11929)
                     /gene="blaI"
                     /locus_tag="FPO55_14775"
     ARG             complement(11553..11929)
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="98.41"
                     /coverage="100.0"
     gene            complement(11919..13676)
                     /gene="blaR1"
                     /locus_tag="FPO55_14780"
     ARG             complement(11923..13676)
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.38"
                     /coverage="100.0"
     gene            13783..14628
                     /gene="blaZ"
                     /locus_tag="FPO55_14785"
     ARG             13784..14625
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(15154..15573)
                     /locus_tag="FPO55_14790"
     CDS             complement(15154..15573)
                     /locus_tag="FPO55_14790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="QNZ59079.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            15697..16668
                     /locus_tag="FPO55_14795"
     CDS             15697..16668
                     /locus_tag="FPO55_14795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="QNZ59080.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFEEFYKTIDQLLKGQHLGRTILKV"
                     /name="oxidoreductase"
     gene            complement(16840..16932)
                     /locus_tag="FPO55_14800"
     CDS             complement(16840..16932)
                     /locus_tag="FPO55_14800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="QNZ59081.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(17089..17436)
                     /locus_tag="FPO55_14805"
     CDS             complement(17089..17436)
                     /locus_tag="FPO55_14805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="QNZ59082.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(17455..18072)
                     /gene="cadD"
                     /locus_tag="FPO55_14810"
     ARG             complement(17459..18072)
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(19196..19380)
                     /locus_tag="FPO55_14815"
                     /pseudo=""
     CDS             complement(19196..19380)
                     /locus_tag="FPO55_14815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002492243.1"
                     /note="frameshifted; incomplete; partial on complete
                     genome; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            19490..20181
                     /locus_tag="FPO55_14820"
                     /pseudo=""
     CDS             19490..20181
                     /locus_tag="FPO55_14820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            complement(20349..20498)
                     /locus_tag="FPO55_14825"
     CDS             complement(20349..20498)
                     /locus_tag="FPO55_14825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QNZ59084.1"
                     /translation="MKIKTFATFTHRQLDKQVNRFLKNDIHVLEIQTHSNWLYISAIVF
                     YEDK"
                     /name="hypothetical protein"
     gene            complement(21046..21361)
                     /locus_tag="FPO55_14830"
                     /pseudo=""
     CDS             complement(21046..21361)
                     /locus_tag="FPO55_14830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002483623.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            complement(21354..21788)
                     /locus_tag="FPO55_14835"
     CDS             complement(21354..21788)
                     /locus_tag="FPO55_14835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein A"
                     /protein_id="QNZ59085.1"
                     /translation="MNDLNDIKYKNEISNHSNHSNQFTHNFDDKEMLLQEFPEQLTNYL
                     LKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHDRGVKGQ
                     KETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication protein A"
     gene            complement(21785..22333)
                     /locus_tag="FPO55_14840"
                     /pseudo=""
     CDS             complement(21785..22333)
                     /locus_tag="FPO55_14840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001638352.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein A"
                     /name="replication protein A"
     ARG             complement(3982..5447)
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="98.36"
                     /coverage="100.0"
     ARG             complement(2984..3882)
                     /name="mphC"
                     /gene="mphC"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="98.66"
                     /coverage="100.0"
     ARG             13784..14628
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     Typing          complement(20843..20990)
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          146..888
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(21049..21223)
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="92.135"
                     /coverage="94.0"
                     /evalue="4.83e-64"
     Typing          complement(21355..22333)
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="98.985"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 ataaatatca taaacctttc ataaaccctt gataaaaagg ttgatggatg tttattttta
       61 tttattaatc actttattat taagcattat aagcttataa tattttatca agggtttata
      121 aacattttat aaagggttga tgatatgaaa agtgtgaaaa agttgagtga agaattaggg
      181 gttagtaagc aaacgatttt taataatatt aagcgattga atatagagac aataaaacag
      241 gaaaacactt cgtttattaa agaagatacc gatatagaaa aaatcattca aagagtaaat
      301 gaaaataaaa agaaatatgg ttttgaaagt actactgaag acaaacaaaa aaaagggtcg
      361 gataatatta attttgaatc gaaaagcgat gctcaaatag tagaaatcct taaaaatcag
      421 attgatactt taaataatca aattgaaaaa caagaaagtc gtcatgaaac aacaattgaa
      481 ttttacagaa aagagttgca agaaagatca aaattgcttg aaaatcagca agttctggca
      541 ttagagagta ataaaaagat tcaaaaatta gaaaatcaat tagaaaaaga aaaacacctt
      601 aattatccct ttgatacatc tactaacact agacaaaacg ttgatgcaca agaaaaaaca
      661 tatactacta atcctgtaaa tattaacaga gatcaggaag aaactaaaga aacagagatt
      721 caatataagg atatatctgg aagtcaaagc gacgaaagta cacaaggtga agaagcaaaa
      781 aaagaagacg ttccagctaa tctaaatgac aatgatagtg atatagaaga aaagagtgaa
      841 gaaacggaac ctaaaaaggg gttttggagt cgtttgtttg gtagctaaaa taattgatta
      901 ggcactaaaa gttataaaat tttagtgtct tttatatagt gagaacttct ggtaatcatc
      961 gattatgtaa actaaagtat ttcaaataat taactgtatt aatactctca tcatgattgc
     1021 gttataaacg ttcgttattg agacaaaatt taatagtact actacacaaa aagagagtgc
     1081 gaattcgcac tctctttttg tgataaatga atggttaaga aaataattca tccacagttg
     1141 tatcaaacaa tcttgccaac ttaaatgcta atgtcaatgt aggatcatat ttattgtttt
     1201 ctattgcatt aatagtttgc ctagacactt ttaattcttt acttaaagtt tcttgagaaa
     1261 ttcctttttg ttttctatat tctctaattc tatttttcat taatttaacc tttagatgta
     1321 tattttttat ttgtagtata gtaattaaac agcataagaa atagtgctac aattataaag
     1381 aaaatttctg gatattgaga aaaccaagat ccttcaatac ttggtgacaa acctgtaaat
     1441 ttaagcacta gtgtaaataa catacaatat acaatccaaa taaaactttt agccagtatt
     1501 tcaataaaca ttttacgttg tctttcatcg tatcgatctt gttgtccttt tttatctaat
     1561 gtttctgaag gtaaatattt gttagttata gccgtccata aacaagaaaa aattaaaata
     1621 ataataaaag gaattaaatt cattataaca cctcataaat gtaaaaagta tttgacattt
     1681 atgagtgtaa atatttttga tacaaatgtc aaatactttt tacattataa tatattttaa
     1741 aacaccttat tagtaaaaca attactatat agaaagctgc gaactcgtac tcttttttct
     1801 tgtataatta ttaaaatctc aattcaataa tatgttatgg aatttgagac actgtgagag
     1861 acgctcattt gcattgacaa tcaatttatc aagataatcc cttatcatgt ttaattctat
     1921 aaactgtttg tcttgtgata ttaacttctt tcgcaatctt actaatcgct ttgccttctt
     1981 ctaacatttc caccacgcga tgataaataa cacgtttctg tgggtcttta gcatttggtg
     2041 aataaagtaa agggcgccct ttatatacgc ctttttcctt cgcaacttga atcccttgcg
     2101 cttgtcgacg tttactttca tttctctctt gttctgaaac cattgctaat atttgaatga
     2161 ttaaatcttt cataaactta tccagtaatg gattgccaat tacttcattc atcataggta
     2221 agctggtaat cattaactga acgtcttttt cttttaaata attcacagtt tcaataattt
     2281 catcatagtt acgtcctaaa cgatcaatag attccacaac gaatcgatct cccattctga
     2341 caaaattgag tgcttcttga aatacaggtc tattttccac tgactttccc gactgtttct
     2401 ctgtaaagat tttctccaca ccaaacgtct ttaaattatc caattgtctt tctaaatttt
     2461 gatctatcga tgatactctc gcataaccta taatcattca tcttcactcc ataataaata
     2521 tacaccctaa tcatacgttt taattgttat aatttcaaca attctttttg tatggttagg
     2581 gtgtactcaa agtgtacata tctataatta aaacttacta aaaataaata tagatttttt
     2641 ctttgtaaca gaaccgttca tttgaaggtc atctctatca taaatattta aattaactaa
     2701 aaattttaat catctgttta atacttatga aatgtattta cggtaggtat taaaattgat
     2761 gaaatttata taagtgcttt caatgaaaat gaccgtttat ttatcctcct gatttaagga
     2821 gttagaaatt tcgaaaacga ttctttccat ttgttgcatt tgttccatgt ccagatattt
     2881 aatacattat agaaaaccaa agaccatcac taattaaacg cagttttaaa atttcatcag
     2941 gattgccttc gtctttaaaa tgggcctctt ttaatataag ttctactctt tcatacctaa
     3001 ctctttcaat gccatcgttt catacgccga ttctcctgat tccatagcaa actcagcgat
     3061 aaacattggg aatactgcat tgagttctat tatatgctct ttcattcgtg gccatatttc
     3121 acctccagct ttaccgtatg ctgttataag ttgctctaat ccttcgtcgt cgaatacacg
     3181 atggtgtcct ataaagtcca ttgatgggtc ggagtgggtt gcttcagtcc agtctatgag
     3241 acctgtgacg tttgcttggt tatctaccat tatatgtcct ggatgtaagt ccccatgtat
     3301 catggtcgca tgtcgaggcc atagttcgtc gttttctaac cattgtttcc atctgttcca
     3361 taattcatct gatacgccat aagtttcttt aactttattc attcttcttt gaaagtcatt
     3421 ttttatttct tgtatggttt tgatatttat atgctgaacg ttaatgtttt cttctggtat
     3481 gttgtgtaaa tctacgagtg tttcagctaa tgtgttaata aagttttctg gtaatggttt
     3541 gtgttcaatt tcccatacat aattttgtat ttctggatct attgtggctg cgggtttacc
     3601 tgtaagtttt gggtaagcaa taaggtcttt tgcatgtact ttccacttcg gtatttcaaa
     3661 tgaaacattc ttctgtaaga agtctaccgt ttgtttttcg ggttttgttc gtttataaac
     3721 gtcaggtctt cttggtagtc tcaaaaccca ttctactcca tgtttatctt ttccaaatgc
     3781 aacttgaaaa tcaagtcccg attcattcaa tgagattgtt tgaggttgga tgtgtaattg
     3841 atatttttct gcacatttaa taatttcatt atgtcgagtc attttattgg atccttattt
     3901 ctattatatt tttcttgtga acgtattttt tatattgata taaatgaacc taatattcaa
     3961 tataaattag tgtatagttt ttaagttata tcatgaagag attgtcctgt taattcccat
     4021 tttttatctg atacatgttt aacaaacctt gtatcatgtg atgtaaacaa aatgattcca
     4081 ggatatttat tcataaacat ttctaatgct tctaatgttt taatatctaa aaaattagtt
     4141 ggttcatcca aaattaacat attcgctttc gttgaaaata atactgctaa cgataatttc
     4201 gttctttccc caccactcaa aacattacaa gaacgatcaa gtgcttcatt taaacccaag
     4261 ttatttaaaa tagctctact gaatgattct gatgaatccg tttcatccat taaatattgc
     4321 aataatgaaa cgtcacgcat gtcttcataa gcaagttgac gatagtatgc catttgcact
     4381 ttaggagaac aatcaattcc ctctatttgg tggtaaatag cttcaagtaa agttgtctta
     4441 cctacaccat ttgcacctac gagcgctata tttttgccat atggtatttg gaatcgtact
     4501 tgtgttagca gtttttgact tcctttaacc aatgttagat tttgtgcaat gattggataa
     4561 ttattatgga tatcataaat tttattttgt gggaaattga attcatgata actttgtggt
     4621 ttttcaactt cttccaaatg ttccattctt ttttcaatat gcttagcttg tttttgagca
     4681 gccttctcaa ccgtgccttt ttgttttgat gcacttaaac gatctggtgc tatacttttg
     4741 tttttttgtt ttgatgatgc ttgtgccatt tgttgcgctt gatttcgttt agctttactg
     4801 gcttgggaca atctttgttt ttcacttata tactgttcat attgacgttg ttgttctaac
     4861 tgttcttgtt catattgatt ttgatactgt gtgtaattac ctttaaacac tcttattgtg
     4921 ccatcttctt gtatatccca aattgtgtca gcaatttggt ctataagtgc tctatcatga
     4981 cttactataa ttaaagtacc atagtaatat tttaaaatat ttttcagata atctttacca
     5041 attttatcca agtgatttgt aggttcatct aaaagtaata tcggactata atttgatatg
     5101 acattagcta atttatattt tgctttttca ccaccactca tactgtcggt tgtatgcata
     5161 ggtatatgga gttcactcat taaactaccg tctaacgtgt taaaatcatt ttccacatcc
     5221 atgttaagct gttcaaaata ttgaatttcg ccaaccgttt caactgttcc agattctggt
     5281 tttgtttttt gagcaatcat atttagtaat gtggttttgc cagtaccatt acccccaata
     5341 agtgctattt tttcaaattg gtaagcgtaa agatgaccga tgttaagtga tcgtaaatct
     5401 gtcaatttat gattgatttg gttaaattta attgtatatt gttccatatt tatacactcc
     5461 ttgtatattt aaaggacgtg tacgcaaaaa aatgagacag gctactcccg tctcattcac
     5521 attacacttt caaacactta aaaatttatt atgatgtttt agtatttgaa agcgtttatt
     5581 attcctatcg aaggataaaa aatgacataa gtcatcctat gagtgtgtat tgcggacaag
     5641 cctttttgaa ttaatttagt tttgtattca aaaaggttta tttgagtctc atagaagctg
     5701 tcattttaat cctccttcat cgataaaata gtaatgttaa tataacattt tgttggtttt
     5761 tttacaatat atctctaagt agaaagatta tataacaaaa gtataaaaat acaattttag
     5821 attgattata catctcctta atttagagtg tactcataaa atacggttct gttgcaaagt
     5881 tgaatttata atataatttt aacaaaaagg agtcttctgt atgaactatt tcagatataa
     5941 acaatttaac aaggatgtta tcactgtagc cgttggctac tatctaagat atgcattgag
     6001 ctatcgtgat atatctgaaa tattaagaga acgtggtgta aacgttcatc attcaacgat
     6061 ctaccgttgg gttcaagaat atgccccaat tttatatcaa atttggaaga aaaagcataa
     6121 aaaagcttat tacaaatggc gtattgatga gacgtatatc aaaataaaag gaaaatggag
     6181 ctatttatat cgtgccattg atacagaggg acatacatta gatatttggt tgcgtaagca
     6241 acgagataat cattcagcat atgcgtttat caaacgtctc attaaacaat ttggtaagcc
     6301 tcaaaaggta gttacagatc aggcaccttc aacgaaggca gcaatggcta aaataattaa
     6361 agcttttaaa cttaaacctg actgtcattg tacatcgaaa tatctgaata acctcattga
     6421 gcaagatcac cgtcatatta aagtaagaaa gacaagatat caaagtatca atacggcaaa
     6481 gaatacttta aaaggtattg aatgtattta cgctctatat aaaaagaacc gtaggtctct
     6541 tcagatctac ggattttccc catgccacga aattagcatc atgctagcaa gttaaacgaa
     6601 cactgacatg atatattagt gattagctat attttttact ttgcaacaga accagccatt
     6661 taatatgact gttacaatta ctaagattca agcactatta cgccgcacgt atgatttcac
     6721 cactcaagtt aataatttaa cagtagatga ttgcgagtta ctacttgatg cagcaaagct
     6781 taaatttaat gaagaaacca tagacctgac acacactgaa ttgcaaatca tgcatagctt
     6841 attccagaac aagggcaaat tcgtcagtcg taatgcgtta atcgaaaaat gctgggaatc
     6901 agaacacttc attgatgaca atacgcttgc tgtcaacatt acacgtttac gcaaaaagct
     6961 acaaaaacta ggacttacag attttatcga aacgaagaaa aatgtcggat atcgtgtagg
     7021 tgacgtatga atttcttgaa atcaatccaa cgtgaaattt atattgtcat ccttacttgt
     7081 gctttattct actttatatt attcatgtat aatgtgccga tgcaagcata tatgattggt
     7141 ctaggtattg tattgtttgt ttcaatgatt tactggggta tccattacat gaactttaaa
     7201 aaagaataaa cactacagga acagaacgaa gatttaagaa tcgaaaacca taaacttcgt
     7261 aatgacttta ttaactacca aagtgagtta gagtcatatt ttttaatgtg ggtgcatcaa
     7321 atcaagacac cgattacagc atcaaagtta ctgcttgaag atcctgatga acacgtgatt
     7381 tctaacgtgc gtaatgaagt cttacaaatt gataattaca cgaatcttgc actgaactat
     7441 ttgaaactca tgaaccaaaa gacatacatg gtctttatgg aagtgagtgt agatgaatta
     7501 attcgaccac tgattaaacg ttatgcgata cagtttattc atcatcaaac aaagttgcat
     7561 tatgagaaaa gtgaagcggt tatattaaca gatgccaaat gggcatcaat tatgattgag
     7621 caaatattaa acaatgcatt aaaatatgca cgtggcaaag atgtgtggat tacgtttgac
     7681 gaaaatacaa agaaattatc aatccgagat aacggtatcg gcattaatgc gagtgattta
     7741 ccgaaaatct ttgataaagg tttctcgggc tataacggta gaataagtga gaaatcaagc
     7801 ggtattggtt tatatattgt cagcacaatc tcaaagcgct taggccataa agtaagtgct
     7861 acatctacat taaacgatgg ttcaatattc accattcaat ttaaataact ccaatctttc
     7921 atttttgtaa gattagcggc tgtttttgta agaatagata aaggcagcct tttctaatcg
     7981 cgcgtaagat aaaggtaaca acaaactaag aaaggtgcca gaggtgaaaa atttgaataa
     8041 tataattgaa ataaataact taacaaagca atatggaagt cagatagcag ttaataattt
     8101 gagtataact gttgaaagtg gacaaattta tggtttttta ggaagaaatg gtgcaggcaa
     8161 aacaactact ataagaatgc ttttaggctt aattaaacct acgaaaggta atattaaaat
     8221 atttgaaaaa gagttcgaaa gtaataaaac tgaaatttta aaaaatattg gtgctatggt
     8281 tgaaacgcca ggtttttata gtaatttgac agctaaagag aacttaacta taaatgctaa
     8341 aatattaggt atacaaaaag aaaatgcaat tgaagaagtg ttagaaatag taggactagc
     8401 ttctgaaaaa gtaaaattgt ttaaaaatta ttctttaggt atgaagcaac gtttagggat
     8461 tgcgagagct ttattgcaca atcccgaatt attgatactt gatgagccga cgaatggatt
     8521 agatcctatt ggcataaaag aaattagaaa gttgattaag gatctggctc aatctagaaa
     8581 tataaccatt ttaatttcaa gtcatatatt gtcagaaata gagcagttag tagacaaggt
     8641 gggtattatt cataacggag ttttgttaga agaaattatg tatgaagatt taaaaaaaaa
     8701 gaacagacaa tttataagta tatcagtatc agatgaagaa aaagttgcat gtttgttgga
     8761 aactaacttc ggaatttatg actataaaat taaagaaaat ggcgaattta aaatttattc
     8821 acatattgat agacaacaag aaattaatag attattagta ttaaacaata ttgatgtttt
     8881 ccagatgaga gtgatagaag ataatctaga aacttatttc gaagacttag taggaggtgg
     8941 cacaattgga taatctactc cgtacagaat ttattaagtt aaaaagatca tatatgtttc
     9001 taataagtat tttaggtaca tgcgtagcac cttttatggt ggttgtagct tcttttatta
     9061 gtatgcggac gaaagtaccg actcctaata ttgtatttaa acagttattt gaagaagtca
     9121 gtttatatca tatgctaatt attggacctc ctctatatgg ggttataata gcctatttgt
     9181 ttggaagaga atatatagaa gatactttaa aaaacttatt aattatacct atatctagag
     9241 aaagtttttt agtaagtaaa ataatattat tattcttgtg gattcaaaca ctatctgtta
     9301 ttgcatggtt gctaacttta atgctaggta tgctattgca ttttcaaggg ttaagccaga
     9361 gtttaataat tgattcattc tttacatttg ttattggcgg agtgttatta tggatattat
     9421 ctccaccaat aattattttg tcgatatatt ttaaaaatta tgttcccaca attgttttaa
     9481 ccataataat tactttgata aatttaatga ctgctaattc tgaacataga ggattatttc
     9541 cttgggctgc agttggagac atatctagag gaacattacc taatacttat ccatttctat
     9601 tatctttaat tatcataatt gttacatcta tattcagtgt aattatatta ttctcatact
     9661 ttaaaaaaac tgatataagt taaaaggagg agaaaaatgg gttttataga gcagattaaa
     9721 gcatttattt taggtgtagt tgaagggttg acagaatttg ctccagtatc atcaacaggt
     9781 catatgatta ttgttgatga tatgtggtta aacactgctg acgatttagg aagtgcgtct
     9841 gcaactactt ttaaggtggt aatacagtta ggaggttctg ttgcaaagtt gaatttataa
     9901 tataatttta acaaaaagga gtcttctgta tgaactattt cagatataaa caatttaaca
     9961 aggatgttat cactgtagcc gttggctact atctaagata tgcattgagc tatcgtgata
    10021 tatctgaaat agttcataca gaagactcct ttttgttaaa attatattat aaattcaact
    10081 ttgcaacaga acctcattta ctatatgggc atctctttca ttattaatac aaagctttgt
    10141 atctccgata ttaggcaaag gtgtaaacga attaggtgat actataggat tcaacattat
    10201 attaatcgtt tctttaataa tgattatctt cttatttttt ataaatcgta gtaaaaatat
    10261 ctcctatgat tatataaaag ttcaaagagg tgaagccaat gaataaatta gaaaaatggt
    10321 ctttggtatt tattattttt acatttctct cttcattagc acttttatat ttcaaatata
    10381 attttagttc ggttatgcca gtcctaagtc tttctatttt aactatacta atattgttga
    10441 cgagtattat tactgtagtt tcagttaatg atgaagatac ttaaaacgtt cattagtgaa
    10501 acaggtatta tattaaaaaa gcgtacgaat ttgtacgctt ttttcttgtg ttattattaa
    10561 aatctcataa caggaaaata ttatgagatt ttagacgctg tcagaacgtc tcttttacat
    10621 cgagtgacat tgaatcaaag tctttgtatg ttaatgatat ataaaattat ttagtagatt
    10681 cattatagta agctagatta gttgctctac ttgtttttat tctcttttgc ctctaattta
    10741 ttgagataac gataaatagt tgtacgtgaa acttgccact gctctgcaat tgttttaatt
    10801 ggcgtaccat tatcataaag tgtcttaagt aagtttaaat cttgtttatt taatttttca
    10861 ggtctacctc catatcggcc tctagcacgt gctgcaattc gaccggctga tgatcgctct
    10921 aaaattaaat tacgttcaaa ctctgcaaat gctgcgaata aatgaaataa taattgtcct
    10981 gtagaacttg atttatccat cgttatattt tcttctaaac tatgaaaact cacacctcgt
    11041 tcgttaagtt cattaactaa cgtgattaaa tcctccatgt tccgtcctag tctatctaat
    11101 ctccaaacaa caatcgtatc tcctgacctc gcaaattcaa ttgctttatc taaaccaggt
    11161 cgcttacttt ttgaaccact catatggtca ttaaatatct tttcacaacc atatgtattt
    11221 aatcgatcct cctgtaaatt caaattttgt aatccagttg aaactcttgc ataacctatt
    11281 ttcaaaatac agacctccta tatacacctt tagtgtacca taacttgatt acgaggtctt
    11341 ttgtgaacat agattttttg ttgggttttt gaacacataa ttctatgtaa tacttactta
    11401 tttagacaaa aaacaagagt gtacagaaaa tggttatttt ctggacactc tcatctttaa
    11461 taatatattt taaatgtcat taacaaaact aatttaataa gagtcaagta tggtttacat
    11521 atgtattatg tttgaaacat acctctaatt actttttact aatatcattt aaaatgtctc
    11581 gcaattcttc aatttctttg ttatttaatt cttcattttt cgcaaaattc agcactaaac
    11641 ttttcatatc ccctccatac agtttattaa gaaaggtttt agcagttttc attttaatat
    11701 cgtcttcttt aatatttgat gagtaaaaat aaatattttc tgatttgtat cgttttataa
    11761 tctctttttt atatagtctt gtgattaatg ttctaatcgt tttatcacta acttctttat
    11821 atttttgaat ttcaactaca atttcattag ctgatactga ttttttatcc catattatat
    11881 tcataacatc ccattcagcc atagatattt caacttgctt attggtcatt taaaacaccc
    11941 attcctttta atattttttc acttattaat tcagcatttt tcccagacgg gtttccatct
    12001 gataaatgtg tagcaaaata atacttatca tgatttgtaa ttacgtaacc tacaaaccac
    12061 ccattattat acttcccgtt tactatacct gtacctgttt tcccatacag ttcatacttt
    12121 tcatttttct taatcaataa tgaagaagat aattgattct ttgctttttt actaaaatgg
    12181 ttattttgtt ccatcatatt tttaaaaact attacttgtt caagattaga tattttcaaa
    12241 ctatcttcca tccaatagct tttataactt cccaaatttt cattaccata atttaattgc
    12301 ttgagttgag ccgcagtata gttctttggt atttgattac taatacgttc gaagtaccaa
    12361 ttaactgaat tttgcattgc tgtatttaaa tcttgttcct tattccaaga ctcgaaaaga
    12421 taatgtttat gattccatga catacgtgaa tttttatcac ttataatatg acggtcaagt
    12481 ccaaacagtg ctaaataaat tttgtaagtt gaatcaggag aatatctttt tctactttct
    12541 ttttcattat aaatatagta tttgtctttc ttcatgctgt acataacgaa agatccacta
    12601 tttgaaccaa aatttttact ttcatctaaa atttggtaat cgctttgtaa gggcttttta
    12661 taattataat cagttaagga ttgccccatt aaaaactggc tttgaattat catgataaaa
    12721 aaagtaaaaa tacaaataaa aattagaatt aattttgact gctttttcag atcggcttct
    12781 tttatattaa ttaatctact tttgagtaat gattttttac cattaaatga atggcttaat
    12841 atatttttgt tggaaaatgg ggtttttaat acggagtcca taatagattc cgcataagtt
    12901 ttaaattcat ttttgttaat attattaagg acaaatctat cggcttctac ttcattgtca
    12961 tgaattatct ttctttttac aatatgtact aatggattgt aactcataat aatagagaag
    13021 atattaaaga taattaaatg taaagtatct ctatttttag catgagcata ttcatgcagt
    13081 attatatatt ttagtctttt atcaattaca cttttaaaat atgaactagg aatcaaaata
    13141 atatatttcc cataccaaaa agttattgga gattgaatag cctctgcttt tcgaatcaca
    13201 atattttttt tatattgatg gttgaaaagt atcgtatcta ttttattttt ttcattttcg
    13261 tttagataaa gtgactgttt ctttaaatat ttaagatata ataaggcttt caaaaattta
    13321 aaacttaaaa taataactaa aactatccaa ataactgtgc agatattatc aattgaatcc
    13381 caattaaact tatggatatc tgttgtgaac tcttgaatag gtttggtggt atttatgtta
    13441 tggttcaaat cgtgtgactt actttcaact gtgggcgctt gattattcac attattaaat
    13501 tttataaaag agaatttaat tgggataaaa ggaattaatc cagcaagcat agttagatac
    13561 caaactttat aatttaaact ataattaaaa tagcgtttta atatgtacct aaaaaatact
    13621 aacaatagaa atataaaaca aaagcttact acgctcatta ttagtaattt agccattttg
    13681 aaaccttctt tcaaatattt ataataaaca attgacatca atattacaat tgtaatatta
    13741 ttgatttata aaaattacaa ctgtaatatc ggagggttta ttttgaaaaa gttaatattt
    13801 ttaattgtaa ttgctttagt tttaagtgca tgtaattcaa acagttcaca tgccaaagag
    13861 ttaaatgatt tagaaaaaaa atataatgct catattggtg tttatgcttt aaatactaaa
    13921 agtggtaagg aagtaaaatt taattcagat aagagatttg cctatgcttc gacttcaaaa
    13981 gcgataaata gtgctatttt gttagaacaa gtaccttata ataagttaaa taaaaaagta
    14041 catattaaca aagatgatat agttgcttat tctcctattt tagaaaaata tgtaggaaaa
    14101 gatatcactt taaaagaact tattgaggct tcaatgacat atagtgataa tacagcaaac
    14161 aataaaatta taaaagaaat cggtggaatc aaaaaagtta aacaacgtct aaaagaacta
    14221 ggagataaag taacaaatcc agttagatat gagatagaat taaattacta ttcaccaaag
    14281 agcaaaaaag atacttcaac gcctgctgct ttcggcaaga ctttaaataa acttatcgca
    14341 aatggaaaat taagcaaaaa aaataaaaat ttcttacttg atttaatgtt taataataaa
    14401 aacggagaca ctttaattaa agatggtgtt ccaaaagact ataaggttgc tgataaaagt
    14461 ggtcaagcaa taacatatgc ttctagaaat gatgttgctt ttgtttatcc taagggccaa
    14521 tctgaaccta ttgttttagt catttttacg aataaagaca ataaaagtga taagccaaat
    14581 gataagttga taagtgaaac cgccaagagt gtaatgaagg aattttaata ttctaaatgc
    14641 ataataaata ctgataacat cttatagttt gtattatatt ttgtattatc gttgacatgt
    14701 ataattttga tatcaaaaac tgattttccc tttattattt tcgagattta ttttcttaat
    14761 tctctttaac aaactagaaa tattgtatat acaaaaaatc ataaataata gatgaatagt
    14821 ttaattatag gtgttcatca atcgaaaaag caacgtatct tatttaaagt gcgttgcttt
    14881 tttctcattt ataaggttaa ataattctca tatatcaagc aaagtgacaa tagcatttta
    14941 caagtatttt ttattgttcg attagggtaa acctaaataa tacataaatt atattacaat
    15001 atgtttatta tagaggctaa agtatcttag aaatttggat agtaggtttt tcgggaataa
    15061 aagtatagtt ggctttaata tataattaag ctaagctatc atttatattt actcgattat
    15121 aattcgcact tcaacttttt tataacgtaa aaattaaaac gtagttttat ttatctttag
    15181 taatatcttt ttaaacacta cagtttcttc attagttaaa ttagcgaagt aatgattatt
    15241 aagttgatag gctttctttt ctaatgttgg ccataagtct tttgctttat ttgtactgtt
    15301 tattagcaca gttcttctat tttcattatc agtttgacgt gttattagat cctttttgga
    15361 catcttatct aatattccag atattgttga aggttctaaa tttaaagtat taccaatcgc
    15421 tttaggtgta ttcaaattac tattaatcaa gcaattcaaa acaccatatt ctgctggagt
    15481 aatattatag ggacttaata aacttttaaa atgtttaaaa actctattct gagaagtact
    15541 caacaaataa tttatacaat tatctaattc cacaactaaa acctctctta aatcattagt
    15601 attgactcgc ttatcatatc atgataagtt ttgtaggaaa atagttttgc aacaaaaaca
    15661 tacttctaca aaacaattgt gaaagaaggc taataaatgt tcaatgcggt agtagtgaga
    15721 aaaagtgcat caaatgttag ttataaagta gaaaaagttg atgaatctca tttatcgaag
    15781 ggtgatgtat tagtaaaagt ggtatactct tcaataaatt ataaggatat gctagcttta
    15841 caatataaag gcggtgtaat tagagattat cctatgattc ctggtataga ttttgcaggt
    15901 attgttgaat caagttcgaa tgataagttt aaagaaggcg ataatgtatt agttactggt
    15961 tatgatgttg gcgtgacaca tacaggtgga ttttcagaat atgcacaagt gcctggagag
    16021 tggattgttc ctattcccca agaaatgtct attaaagagt ctatggtata tggcacagcc
    16081 ggttttacgg cagcattatc aatttttgaa ctagaaaaat atggaatgaa tatcaaatca
    16141 caacctgaaa ttttagtgtc tggggctaca ggtggtgtgg gcagtgttgc tatacaaatt
    16201 ttacataaaa ttggatatga aaatatcact gctatcgtaa gaaaagaaaa gcaaatagaa
    16261 atcgcaaaaa aattaggtgc aaaacaagta ataataattg aagatgataa taaaccgctt
    16321 aaaaaaggta tttttgatta tttcttagat acagtgggga gtaatgtaac attatacggt
    16381 ttaaaacgtc taaattatca aggtgttgct actgtatgtg gaaatgtagc aggaaattca
    16441 cttaacgcta atatattacc gtttattctt agaggtatta aattaattgg cattgattct
    16501 gtatatgttg atcataatat ccgtgaagat atatggagta agttagcaaa tgaatggaat
    16561 ataggaaatt cacttctata caatgaaatt ggatttgaag aattctataa aacgatagat
    16621 cagcttttaa aaggacaaca tttaggaaga actattttaa aagtataagt gtgagtattc
    16681 attaatacat ttactattaa ttcaatcatt ttgcatttct ctactaacca gtgttataat
    16741 ttatataacg aaaatgatta acaattaatg caccaatccc cacactattg cagtagtgtg
    16801 gggatttttt cgatgctggc ttataaagtc gcctattaat tatttgttgc gtttactaag
    16861 ccaataagta taatacgcaa cagcacagcc actgatgact ggtgctatga tgtgaacgaa
    16921 aatgattagc aaagtaatgc acctcctctc ttcgtcaatt gacgcctgag agataggcga
    16981 ctctattatt ataccatctg tgaatataca agcatatcta cttccgataa gtcgtcttat
    17041 gttatataac tttgtttttt atagtatcaa gacaagaaga aactcgtttc aaaaaccctc
    17101 atgattttta gagaaaaact ctcttatttc atcgtcttta ataaaataat atgccatctt
    17161 tccatcttta taaaaatcaa gtacctcatt tttatataaa agccttaaat gatgtgaagt
    17221 tgaagcaaca ctcattttca atatcaaaga aatatcacaa acacacaact catcttcttt
    17281 aatcaaagat aatatgattt tcaatttctt ctcatcacaa attttttcta aaatgttaag
    17341 taatttctta gatttatcat cttctaaaaa acttaaagca ttgttaactt tatcctcatg
    17401 tacacagatc acatcacaag tattttcata actcatataa aatcacaccc taaattaaaa
    17461 tataaatcct aaaattgttt gaatagtgtc attttcaata ataataaata aacctaaagc
    17521 tatataaata atagccataa tccaacgact aaatttctca acaatttctc caattcctgg
    17581 aatattagct aatttttgtg cagtaaacac caagaagaaa attaaaatta aaaagacaaa
    17641 cagagtaagt aataaattag taacacttaa tgtcacaaaa tacggaacaa ataaaccaat
    17701 attatcggcg ccacaacttg ctatcgtaac aattgcaacc gtaccaacta atttagacaa
    17761 tcctttttca ttcaattctt ttttagctct cttttctcct tcacaatcat cataaatagc
    17821 cactttaatt ccaagataaa ttggtattaa acccaataaa cctaatatcc acttttctgg
    17881 aacataattt aatacaaaag ctaaaaacaa actaactaat attaaaataa tagaccctaa
    17941 atattgacca acataaatat ctctatattc ttttctagtc tttgctctag caaaaaatat
    18001 taataaaatt actaataaat caactgctgt agcaatataa agaacagcag cagcaacaac
    18061 cgtttgaatc ataatacacc tcattcaaaa atatttttga atgtattata acttatattt
    18121 ttaaataatc ataggtgctt tattccaatt gctttattga cgttgagcct cggaaccctt
    18181 aacaatccca aaacttgtcg aatggtcggc ttaatagctc acgctatgcc gacattcgtc
    18241 tgcaagttta gttaagggtt cttctcaaca tcaataaatt ttttcggcat aaatgcgtgt
    18301 ctatgcgtag acatggagac acttcagaat tatggagtga ttacatgagt ttaactattt
    18361 ttctttattc agttttagga agtttattag caaattatat ctacgaaaaa tcttcaaaat
    18421 aaataacttt ttcggttcta ctttgtacac tttatctacc tggtagacct aattgttatt
    18481 gctttacagg tctaaaattc gtcgttataa tctagttaaa tcccgtaagg gcgcacttat
    18541 acgtcggata aatcgacatg tgcaaaaacg taatcgacct tcgtcgattt ttttatttca
    18601 aaattaaaga aacggcttga gatattccga gcagttataa aaattaattt gcgttgaata
    18661 ttgctactac attcttgaaa aagtgatgta gatttatagc ccataacttt tttgaattac
    18721 atcgacgata cggcgtcgaa agaaaaataa atagaccgta tgaaagaaaa agctacctca
    18781 ctttatctgg gtagctttta ttttttatgc ccttattttg aattttaaga gggcatttta
    18841 aagatttagg ggtgattcat atagttttat atctaaaact tatatatgct tttaaaacgc
    18901 aaatatgagc caaataaata tatgctattt tcaaaaacaa aaatttgagc aaaaacaata
    18961 actattttta gacactgccc atttacatgc aaattaaaaa ttagcataaa attctttaaa
    19021 acttccccac gtttttctaa attcctgtag ggcgtttttt atcaaaaatc aagacaagaa
    19081 gaaactcgtt cacactcgtt tcaaaaaaac aagaaatcta atctatacac ctaccgtttt
    19141 ccaaccccct caaagcatac aaattaaaaa caaaattatt cataatctta ctttctttta
    19201 acaaaacata aaaaccataa atagacaaat taactatcaa aggcaataaa cagtataaaa
    19261 aaaccacgaa taaatcttca tcaacatcta aaataaaaaa gaataaacaa ttaacaaaat
    19321 actaattaac aaacctaaaa gtggcaaact ttttatatat ttttctaaat tttcattcat
    19381 aaaatagact cctttcaaaa atatgtttat aaatatatta aaataaatat tgattttata
    19441 aagcgcttac ttatacaatt aaaatatctt attatcttgg aggtatcaaa tgaaaattat
    19501 aaaattattt tcaataattt ccttgttcct actggtattt agcgcgaatt tttctaatgc
    19561 ttacgcaaat gaagaacaaa aaagttcttt actagaaaat caaaaagaaa aattgaaaag
    19621 caaaacatcg aagtatcaca aatgaccaag aaagaaataa gttttctaga acaattgcaa
    19681 aataaaaatg aagatatgca aaaattcgaa aagcaaatga aaaaagaagg atttaaaaaa
    19741 taaagctaga agacaaaaat tctaaattaa aatatctagc tacagaagca aatgataaaa
    19801 atgcatatgg ctacatagct aataacgctt tataaaaatg aaaaaacaaa agaaattgta
    19861 gtttctgaaa caatatatga taactacaac aaaaaaaaat cacaaaattc attgccgaaa
    19921 aagaagtatg actgaaaaca aagagggaaa aatacttatt aacaaaaatt acgttgaata
    19981 taaggctgaa aagttgataa aaacagaccg gtaacatatg caggattcaa atggaacggc
    20041 aaagcattcg cttgtagtat ggctggactt tatgcatgtg ctcactactg tggagtatgg
    20101 gcaatcgtaa atccaatagc cggcggtgta tgtgaagcag tttgcggaac tgcatttgca
    20161 gctggatgct ctgtaggttg attttattcc aattgtttta ttgacgttga gcctcggaac
    20221 ccttaacaat cccaaaactt gtcgaatggt cggcttaata gctcacgcta tgccgacatt
    20281 cgtctgcaag tttagttaag ggttcttctc aacatcaata aattttttcg gcataaatac
    20341 gatgttcctt atttatcctc ataaaaaaca atagctgaaa tatataacca attactgtgt
    20401 gtttgaattt ctaatacatg aatatcattc tttaaaaacc tattaacttg tttatctaat
    20461 tgacgatgag taaaagtagc gaaagtttta atcttcatga tatctctcct tttataaaaa
    20521 tagcaatcct tattacaata ttaaacactt ttattttgga ttttaagagg cattttgaag
    20581 acttagaggc aaatcatata ggttttgtac ttaaaaatct atacagtctc ttaaaacgca
    20641 aatatgagcc aaataaatat atgctaattt cacaaacaaa aatttcagca aaatcagtga
    20701 ctaatttttt agatactgcc catttacatg caaatttaaa aattagcata aaatacttta
    20761 aaacttccca tgttttttct aaattcctgc agggcttttc ttatcaaaaa cttagaaatt
    20821 tttaatttaa ctctaaaatc tccgtaagag cataagggaa atttgctatc attcaaaaat
    20881 gatagatctg gcaaggccag acattccaag ggttttaagt tattttaaag tgatatcata
    20941 caaagctgta gtgtcacact tttgtgacac tacatacagc atttgtcaca aaaataagac
    21001 agcacttttt tacagaaaaa caataaaaaa agacatcagt tatcactaat gtcttaaata
    21061 ataattttgc ttttcgaaat tccaaattgc ggtaattgaa tgtgcttttt ttcttcgtct
    21121 gtcgttttat cttcatcact tgtattaatc aaattaccat cttcggcatc gtctaagtta
    21181 aaattttatg cttttgttta agcaatccac cataacttaa catacgtttt cgatacaaac
    21241 ctttttctaa atcacttaca atttcttgat ttttttcgtc gtcatcagtt aaaaagtcag
    21301 atgatttaac ggaatatttt gatgtctctt cgagtgttat aaaatcattt gaattattga
    21361 ttaaagatat tatattgttt catgttttta cggcgcatat aaagggcatg tgtttcttca
    21421 agttcagtta gaattgtttg cattaaataa gcttgcattg acttgattgt ttccttttgg
    21481 cctttaactc ccctatcatg tatagctttt ttaagtcttt ttaaagaagt taatatttca
    21541 tcctcaatgt cctctaacat gtaatgcata tcttcatgcc ttgaattaaa tgattttttt
    21601 gctttaagaa taacagcctt tatgatttct aaatctctat aatcatattt taataaataa
    21661 ttagttagtt gttctgggaa ttcttgcaat agcatttctt tatcatcaaa attatgtgta
    21721 aattgatttg aatgatttga atgattacta atttcatttt tgtactttat atcattcaag
    21781 tcattcatat cattattctc agtatcatta aagtcaatgt cattaaagtc agtatcatta
    21841 gtgttcgatt ttcgaacttt ggacgttcga ttttcgaact tctggacgtt cgattttcga
    21901 acttctggac gttcgatttt cttccttctc gccgtaaggt tcaacatcgt tttctttctt
    21961 tttctatttt gtaaatatca cgttctgtga caataggttt cattaaatat agaatatttg
    22021 gtttatttaa accacgtcgt ttttgaatga gtagaccatc gttttctaac ccttttttta
    22081 tttttgttaa cttttctttt ttacaattta agatttccat tagcttttca tttgaataaa
    22141 caaagtaaat gttaccatct tcatcaaccc agctattttt aatagataaa tttaagcgat
    22201 cacgtaagat agcataggct attttcatat cattagttag atttttataa ttttcactgg
    22261 taaagaatac tttagggatt tgataaaatc tttctttgta attttcttgc actgtaaaat
    22321 attgattttg catgacaaaa aacctctttc catattttag tttggtaaga ggtaataaaa
    22381 cgtttttatt tagctttaca tttttaatga tttaggtgct tgcactaaga tattattcat
    22441 tatataatac aagtatcgaa aattatataa ataaacagtt tctaaacgtt ttattaccaa
    22501 accccgacta ttaccagtag ttggggtttt tgttatatta agtttattat agcactttaa
    22561 ataaacttat aaaagggaaa atatagcttt atcaagggtt tataaaccct tg
//
