LOCUS       CP049404               22992 bp    DNA     circular BCT 24-SEP-2020
DEFINITION  Staphylococcus aureus strain pt276 plasmid pER07465.3A.1, complete
            sequence.
ACCESSION   CP049404
VERSION     CP049404.1
DBLINK      BioProject: PRJNA470993
            BioSample: SAMN12331093
KEYWORDS    .
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 22992)
  AUTHORS   Caban,A.B., Pak,T., Kumaresh,A., Dupper,A., Chacko,K.,
            Sullivan,M.J., Altman,D.R. and van Bakel,H.
  TITLE     PathoSPOT genomic surveillance reveals prolonged under the radar
            outbreaks of nosocomial methicillin resistant S. aureus bloodstream
            infections
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 22992)
  AUTHORS   Caban,A.B., Pak,T., Kumaresh,A., Dupper,A., Chacko,K.,
            Sullivan,M.J., Altman,D.R. and van Bakel,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-FEB-2020) Genetics and Genomic Sciences, Icahn School
            of Medicine, One Gustave L. Levy Place Box 1498, New York, NY 10029,
            USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.3.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 148.998774501992x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/28/2020 16:03:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 4.11
            Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region
            Genes (total)                     :: 2,926
            CDSs (total)                      :: 2,846
            Genes (coding)                    :: 2,740
            CDSs (with protein)               :: 2,740
            Genes (RNA)                       :: 80
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 106
            CDSs (without protein)            :: 106
            Pseudo Genes (ambiguous residues) :: 0 of 106
            Pseudo Genes (frameshifted)       :: 83 of 106
            Pseudo Genes (incomplete)         :: 25 of 106
            Pseudo Genes (internal stop)      :: 11 of 106
            Pseudo Genes (multiple problems)  :: 13 of 106
            ##Genome-Annotation-Data-END##
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..22992
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="pt276"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="pER07465.3A.1"
                     /geo_loc_name="USA:New York City"
                     /lat_lon="40.7903114 N 73.9528738 W"
                     /collection_date="2016"
                     /collected_by="Mount Sinai Hospital"
     gene            complement(join(21746..22992,1..215))
                     /gene="msr(A)"
                     /locus_tag="FPP39_00005"
                     /pseudo=""
     CDS             complement(join(21746..22992,1..215))
                     /gene="msr(A)"
                     /locus_tag="FPP39_00005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002447408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(A)"
                     /name="msr(A)"
     gene            689..1363
                     /locus_tag="FPP39_00010"
     CDS             689..1363
                     /locus_tag="FPP39_00010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="QNW26110.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            1421..1798
                     /locus_tag="FPP39_00015"
                     /pseudo=""
     CDS             1421..1798
                     /locus_tag="FPP39_00015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866106.1"
                     /note="incomplete; partial on complete genome; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /name="response regulator transcription factor"
     gene            1795..2676
                     /locus_tag="FPP39_00020"
                     /pseudo=""
     CDS             1795..2676
                     /locus_tag="FPP39_00020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501406.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /name="HAMP domain-containing histidine kinase"
     gene            2792..3721
                     /locus_tag="FPP39_00025"
     CDS             2792..3721
                     /locus_tag="FPP39_00025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000074567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="QNW26111.1"
                     /translation="MKNLNNIIEINNLTKQYGSQIAVNNLSITVESGQIYGFLGRNGAG
                     KTTTIRMLLGLIKPTKGNIKIFEKEFESNKTEILKNIGAMVETPGFYSNLTAKENLTIN
                     AKILGIQKENAIEEVLEIVGLASEKVKLFKNYSLGMKQRLGIARALLHNPELLILDEPT
                     NGLDPIGIKEIRKLIKDLAQSRNITILISSHILSEIEQLVDKVGIIHNGVLLEEIMYED
                     LKKKNRQFISISVSDEEKVACLLETNFGIYDYKIKENGEFKIYSHIDRQQEINRLLVLN
                     NIDVFQMRVIEDNLETYFEDLVGGGTIG"
                     /name="ABC transporter ATP-binding protein"
     gene            3714..4457
                     /locus_tag="FPP39_00030"
     CDS             3714..4457
                     /locus_tag="FPP39_00030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000369394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="QNW26112.1"
                     /translation="MDNLLRTEFIKLKRSYMFLISILGTCVAPFMVVVASFISMRTKVP
                     TPNIVFKQLFEEVSLYHMLIIGPPLYGVIIAYLFGREYIEDTLKNLLIIPISRESFLVS
                     KIILLFLWIQTLSVIAWLLTLMLGMLLHFQGLSQSLIIDSFFTFVIGGVLLWILSPPII
                     ILSIYFKNYVPTIVLTIIITLINLMTANSEHRGLFPWAAVGDISRGTLPNTYPFLLSLI
                     IIIVTSIFSVIILFSYFKKTGSVAK"
                     /name="ABC transporter permease"
     gene            complement(4499..5173)
                     /locus_tag="FPP39_00035"
     CDS             complement(4499..5173)
                     /locus_tag="FPP39_00035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="QNW26113.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            5435..5620
                     /locus_tag="FPP39_00040"
     CDS             5435..5620
                     /locus_tag="FPP39_00040"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QNW26114.1"
                     /translation="MNKLEKWSLVFIIFTFLSSLALLYFKYNFSSVMPVLSLSILTILI
                     LLTSIITVVSVNDEDT"
                     /name="hypothetical protein"
     gene            complement(5843..6421)
                     /locus_tag="FPP39_00045"
     CDS             complement(5843..6421)
                     /locus_tag="FPP39_00045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="QNW26115.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEAKENKNK"
                     /name="recombinase family protein"
     gene            complement(6685..7065)
                     /gene="blaI"
                     /locus_tag="FPP39_00050"
     ARG             complement(6689..7065)
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="98.41"
                     /coverage="100.0"
     gene            complement(7055..8812)
                     /gene="blaR1"
                     /locus_tag="FPP39_00055"
     ARG             complement(7059..8812)
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.38"
                     /coverage="100.0"
     gene            8919..9764
                     /gene="blaZ"
                     /locus_tag="FPP39_00060"
     ARG             8920..9761
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(10290..10709)
                     /locus_tag="FPP39_00065"
     CDS             complement(10290..10709)
                     /locus_tag="FPP39_00065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="QNW26119.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            10833..11804
                     /locus_tag="FPP39_00070"
     CDS             10833..11804
                     /locus_tag="FPP39_00070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="QNW26120.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFEEFYKTIDQLLKGQHLGRTILKV"
                     /name="oxidoreductase"
     gene            complement(11976..12068)
                     /locus_tag="FPP39_00075"
     CDS             complement(11976..12068)
                     /locus_tag="FPP39_00075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="QNW26121.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(12225..12572)
                     /locus_tag="FPP39_00080"
     CDS             complement(12225..12572)
                     /locus_tag="FPP39_00080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="QNW26122.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(12591..13208)
                     /gene="cadD"
                     /locus_tag="FPP39_00085"
     ARG             complement(12595..13208)
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(14323..14517)
                     /locus_tag="FPP39_00090"
     CDS             complement(14323..14517)
                     /locus_tag="FPP39_00090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QNW26124.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     gene            14627..15319
                     /locus_tag="FPP39_00095"
     CDS             14627..15319
                     /locus_tag="FPP39_00095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QNW26125.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVE
                     YKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTA
                     FAAGCSVG"
                     /name="hypothetical protein"
     gene            complement(15487..15636)
                     /locus_tag="FPP39_00100"
     CDS             complement(15487..15636)
                     /locus_tag="FPP39_00100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QNW26126.1"
                     /translation="MKIKTFATFTHRQLDKQVNRFLKNDIHVLEIQTHSNWLYISAIVF
                     YEDK"
                     /name="hypothetical protein"
     gene            complement(16183..16499)
                     /locus_tag="FPP39_00105"
                     /pseudo=""
     CDS             complement(16183..16499)
                     /locus_tag="FPP39_00105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002483623.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /name="protein rep"
     gene            complement(16492..17484)
                     /locus_tag="FPP39_00110"
     CDS             complement(16492..17484)
                     /locus_tag="FPP39_00110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="QNW26127.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNK
                     PNILYLMKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSKIERPEVRK
                     SNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNHSNQFTHNFDDKEMLLQE
                     FPEQLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKA
                     IHDRGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication protein"
     gene            17910..18653
                     /locus_tag="FPP39_00115"
     CDS             17910..18653
                     /locus_tag="FPP39_00115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002508633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="QNW26128.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     gene            complement(18880..19065)
                     /locus_tag="FPP39_00120"
     CDS             complement(18880..19065)
                     /locus_tag="FPP39_00120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016912974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="QNW26129.1"
                     /translation="MKNRIREYRKQKGISQETLSKELKVSRQTINAIENNKYDPTLTLA
                     FKLARLFDTTVDELFS"
                     /name="helix-turn-helix transcriptional regulator"
     gene            complement(19070..19408)
                     /locus_tag="FPP39_00125"
     CDS             complement(19070..19408)
                     /locus_tag="FPP39_00125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QNW26130.1"
                     /translation="MNLIPFIIILIFSCLWTAITNKYLPSETLDKKGQQDRYDERQRKM
                     FIEILAKSFIWIVYCMLFTLVLKFTGLSPSIEGSWFSQYPEIFFIIVALFLMLFNYYTT
                     NKKYTSKG"
                     /name="hypothetical protein"
     gene            complement(19654..20262)
                     /locus_tag="FPP39_00130"
     CDS             complement(19654..20262)
                     /locus_tag="FPP39_00130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="QNW26131.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEIIETVNYLKEKDVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRV
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDKGLS"
                     /name="recombinase family protein"
     gene            complement(20748..21647)
                     /gene="mph(C)"
                     /locus_tag="FPP39_00135"
     ARG             complement(20752..21647)
                     /name="mph(C)"
                     /gene="mph(C)"
                     /gene_name="Mph(C) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(21747..22024)
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="96.74"
                     /coverage="18.85"
     ARG             complement(4..215)
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="97.18"
                     /coverage="14.55"
     ARG             complement(20749..21647)
                     /name="mphC"
                     /gene="mphC"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="98.66"
                     /coverage="100.0"
     ARG             8920..9764
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     Typing          complement(15980..16127)
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          complement(16186..16361)
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="92.697"
                     /coverage="94.0"
                     /evalue="1.04e-65"
     Typing          complement(16493..17484)
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="98.691"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          17911..18653
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 tcaaaatatt gaatttcgcc aaccgtttca actgttccag attctggttt tgttttttga
       61 gcaatcatat ttagtaatgt ggttttgcca gtaccattac ccccaataag tgctattttt
      121 tcaaattggt aagcgtaaag atgaccgatg ttaagtgatc gtaaatctgt caatttatga
      181 ttgatttggt taaatttaat tgtatattgt tccatattta tacactcctt gtatatttaa
      241 aggacgtgta cgcaaaaaaa tgagacaggc tactcccgtc tcattcacat tacactttca
      301 aacacttaaa aatttattat gatgttttag tatttgaaag cgtttattat tcctatcgaa
      361 ggataaaaaa tgacataagt catcctatga gtgtgtattg cggacaagcc tttttgaatt
      421 aatttagttt tgtattcaaa aaggtttatt tgagtctcat agaagctgtc attttaatcc
      481 tccttcatcg ataaaatagt aatgttaata taacattttg ttggtttttt tacaatatat
      541 ctctaagtag aaagattata taacaaaagt ataaaaatac aattttagat tgattataca
      601 tctccttaat ttagagtgta ctcataaaat acggttctgt tgcaaagttg aatttataat
      661 ataattttaa caaaaaggag tcttctgtat gaactatttc agatataaac aatttaacaa
      721 ggatgttatc actgtagccg ttggctacta tctaagatat gcattgagct atcgtgatat
      781 atctgaaata ttaagagaac gtggtgtaaa cgttcatcat tcaacgatct accgttgggt
      841 tcaagaatat gccccaattt tatatcaaat ttggaagaaa aagcataaaa aagcttatta
      901 caaatggcgt attgatgaga cgtatatcaa aataaaagga aaatggagct atttatatcg
      961 tgccattgat acagagggac atacattaga tatttggttg cgtaagcaac gagataatca
     1021 ttcagcatat gcgtttatca aacgtctcat taaacaattt ggtaagcctc aaaaggtagt
     1081 tacagatcag gcaccttcaa cgaaggcagc aatggctaaa ataattaaag cttttaaact
     1141 taaacctgac tgtcattgta catcgaaata tctgaataac ctcattgagc aagatcaccg
     1201 tcatattaaa gtaagaaaga caagatatca aagtatcaat acggcaaaga atactttaaa
     1261 aggtattgaa tgtatttacg ctctatataa aaagaaccgt aggtctcttc agatctacgg
     1321 attttcccca tgccacgaaa ttagcatcat gctagcaagt taaacgaaca ctgacatgat
     1381 atattagtga ttagctatat tttttacttt gcaacagaac cagccattta atatgactgt
     1441 tacaattact aagattcaag cactattacg ccgcacgtat gatttcacca ctcaagttaa
     1501 taatttaaca gtagatgatt gcgagttact acttgatgca gcaaagctta aatttaatga
     1561 agaaaccata gacctgacac acactgaatt gcaaatcatg catagcttat tccagaacaa
     1621 gggcaaattc gtcagtcgta atgcgttaat cgaaaaatgc tgggaatcag aacacttcat
     1681 tgatgacaat acgcttgctg tcaacattac acgtttacgc aaaaagctac aaaaactagg
     1741 acttacagat tttatcgaaa cgaagaaaaa tgtcggatat cgtgtaggtg acgtatgaat
     1801 ttcttgaaat caatccaacg tgaaatttat attgtcatcc ttacttgtgc tttattctac
     1861 tttatattat tcatgtataa tgtgccgatg caagcatata tgattggtct aggtattgta
     1921 ttgtttgttt caatgattta ctggggtatc cattacatga actttaaaaa agaataaaca
     1981 ctacaggaac agaacgaaga tttaagaatc gaaaaccata aacttcgtaa tgactttatt
     2041 aactaccaaa gtgagttaga gtcatatttt ttaatgtggg tgcatcaaat caagacaccg
     2101 attacagcat caaagttact gcttgaagat cctgatgaac acgtgatttc taacgtgcgt
     2161 aatgaagtct tacaaattga taattacacg aatcttgcac tgaactattt gaaactcatg
     2221 aaccaaaaga catacatggt ctttatggaa gtgagtgtag atgaattaat tcgaccactg
     2281 attaaacgtt atgcgataca gtttattcat catcaaacaa agttgcatta tgagaaaagt
     2341 gaagcggtta tattaacaga tgccaaatgg gcatcaatta tgattgagca aatattaaac
     2401 aatgcattaa aatatgcacg tggcaaagat gtgtggatta cgtttgacga aaatacaaag
     2461 aaattatcaa tccgagataa cggtatcggc attaatgcga gtgatttacc gaaaatcttt
     2521 gataaaggtt tctcgggcta taacggtaga ataagtgaga aatcaagcgg tattggttta
     2581 tatattgtca gcacaatctc aaagcgctta ggccataaag taagtgctac atctacatta
     2641 aacgatggtt caatattcac cattcaattt aaataactcc aatctttcat ttttgtaaga
     2701 ttagcggctg tttttgtaag aatagataaa ggcagccttt tctaatcgcg cgtaagataa
     2761 aggtaacaac aaactaagaa aggtgccaga ggtgaaaaat ttgaataata taattgaaat
     2821 aaataactta acaaagcaat atggaagtca gatagcagtt aataatttga gtataactgt
     2881 tgaaagtgga caaatttatg gttttttagg aagaaatggt gcaggcaaaa caactactat
     2941 aagaatgctt ttaggcttaa ttaaacctac gaaaggtaat attaaaatat ttgaaaaaga
     3001 gttcgaaagt aataaaactg aaattttaaa aaatattggt gctatggttg aaacgccagg
     3061 tttttatagt aatttgacag ctaaagagaa cttaactata aatgctaaaa tattaggtat
     3121 acaaaaagaa aatgcaattg aagaagtgtt agaaatagta ggactagctt ctgaaaaagt
     3181 aaaattgttt aaaaattatt ctttaggtat gaagcaacgt ttagggattg cgagagcttt
     3241 attgcacaat cccgaattat tgatacttga tgagccgacg aatggattag atcctattgg
     3301 cataaaagaa attagaaagt tgattaagga tctggctcaa tctagaaata taaccatttt
     3361 aatttcaagt catatattgt cagaaataga gcagttagta gacaaggtgg gtattattca
     3421 taacggagtt ttgttagaag aaattatgta tgaagattta aaaaaaaaga acagacaatt
     3481 tataagtata tcagtatcag atgaagaaaa agttgcatgt ttgttggaaa ctaacttcgg
     3541 aatttatgac tataaaatta aagaaaatgg cgaatttaaa atttattcac atattgatag
     3601 acaacaagaa attaatagat tattagtatt aaacaatatt gatgttttcc agatgagagt
     3661 gatagaagat aatctagaaa cttatttcga agacttagta ggaggtggca caattggata
     3721 atctactccg tacagaattt attaagttaa aaagatcata tatgtttcta ataagtattt
     3781 taggtacatg cgtagcacct tttatggtgg ttgtagcttc ttttattagt atgcggacga
     3841 aagtaccgac tcctaatatt gtatttaaac agttatttga agaagtcagt ttatatcata
     3901 tgctaattat tggacctcct ctatatgggg ttataatagc ctatttgttt ggaagagaat
     3961 atatagaaga tactttaaaa aacttattaa ttatacctat atctagagaa agttttttag
     4021 taagtaaaat aatattatta ttcttgtgga ttcaaacact atctgttatt gcatggttgc
     4081 taactttaat gctaggtatg ctattgcatt ttcaagggtt aagccagagt ttaataattg
     4141 attcattctt tacatttgtt attggcggag tgttattatg gatattatct ccaccaataa
     4201 ttattttgtc gatatatttt aaaaattatg ttcccacaat tgttttaacc ataataatta
     4261 ctttgataaa tttaatgact gctaattctg aacatagagg attatttcct tgggctgcag
     4321 ttggagacat atctagagga acattaccta atacttatcc atttctatta tctttaatta
     4381 tcataattgt tacatctata ttcagtgtaa ttatattatt ctcatacttt aaaaaaactg
     4441 gttctgttgc aaagtaaaaa aatatagcta accactaatt tatcatgtca gtgttcgctt
     4501 aacttgctag catgatgcta atttcgtggc atggcgaaaa tccgtagatc tgaagagacc
     4561 tgcggttctt tttatataga gcgtaaatac actcaatacc ttttaaagta ttctttgctg
     4621 tattgatact ttgatacctt gtctttctta ctttaatatg acggtgatct tgctcaatga
     4681 ggttattcag atatttcgat gtacaatggc agtcaggttt aagtttaaaa gctttaatta
     4741 ctttaaccat tgctaccttc gttgaaggtg cctgatctgt aattaccttt tgaggtttac
     4801 caaattgttt aatgagacgt ttgataaacg catatgctga atgattatct cgttgcttac
     4861 gcaaccaaat atctaatgta tgtccctctg catcaatggc acgatataaa tagctccatt
     4921 ttccttttat tttgatgtac gtctcatcaa tacgccattt gtaataagct tttttatgct
     4981 ttttcttcca aatttgatat aaaattgggg catattcttg aacccaacgg tagaccgttg
     5041 aatgatgaac gtttacacca cgttccctta atatttcaga tatatcacga taactcaatg
     5101 catatcttag atagtagcca acagctacag tgataacatc cttgttaaat tgtttatatc
     5161 tgaaatagtt catacagaag actccttttt gttaaaatta tactataaat tcaactttgc
     5221 aacagaacct catttactat atgggcatct ctttcattat taatacaaag ctttgtatct
     5281 ccgatattag gcaaaggtgt aaacgaatta ggtgatacta taggattcaa cattatatta
     5341 atcgtttctt taataatgat tatcttctta ttttttataa atcgtagtaa aaatatctcc
     5401 tatgattata taaaagttca aagaggtgaa gccaatgaat aaattagaaa aatggtcttt
     5461 ggtatttatt atttttacat ttctctcttc attagcactt ttatatttca aatataattt
     5521 tagttcggtt atgccagtcc taagtctttc tattttaact atactaatat tgttgacgag
     5581 tattattact gtagtttcag ttaatgatga agatacttaa aacgttcatt agtgaaacag
     5641 gtattatatt aaaaaagcgt acgaatttgt acgctttttt cttgtgttat tattaaaatc
     5701 tcataacagg aaaatattat gagattttag acgctgtcag aacgtctctt ttacatcgag
     5761 tgacattgaa tcaaagtctt tgtatgttaa tgatatataa aattatttag tagattcatt
     5821 atagtaagct agattagttg ctctacttgt ttttattctc ttttgcctct aatttattga
     5881 gataacgata aatagttgta cgtgaaactt gccactgctc tgcaattgtt ttaattggcg
     5941 taccattatc ataaagtgtc ttaagtaagt ttaaatcttg tttatttaat ttttcaggtc
     6001 tacctccata tcggcctcta gcacgtgctg caattcgacc ggctgatgat cgctctaaaa
     6061 ttaaattacg ttcaaactct gcaaatgctg cgaataaatg aaataataat tgtcctgtag
     6121 aacttgattt atccatcgtt atattttctt ctaaactatg aaaactcaca cctcgttcgt
     6181 taagttcatt aactaacgtg attaaatcct ccatgttccg tcctagtcta tctaatctcc
     6241 aaacaacaat cgtatctcct gacctcgcaa attcaattgc tttatctaaa ccaggtcgct
     6301 tactttttga accactcata tggtcattaa atatcttttc acaaccatat gtatttaatc
     6361 gatcctcctg taaattcaaa ttttgtaatc cagttgaaac tcttgcataa cctattttca
     6421 aaatacagac ctcctatata cacctttagt gtaccataac ttgattacga ggtcttttgt
     6481 gaacatagat tttttgttgg gtttttgaac acataattct atgtaatact tacttattta
     6541 gacaaaaaac aagagtgtac agaaaatggt tattttctgg acactctcat ctttaataat
     6601 atattttaaa tgtcattaac aaaactaatt taataagagt caagtatggt ttacatatgt
     6661 attatgtttg aaacatacct ctaattactt tttactaata tcatttaaaa tgtctcgcaa
     6721 ttcttcaatt tctttgttat ttaattcttc atttttcgca aaattcagca ctaaactttt
     6781 catatcccct ccatacagtt tattaagaaa ggttttagca gttttcattt taatatcgtc
     6841 ttctttaata tttgatgagt aaaaataaat attttctgat ttgtatcgtt ttataatctc
     6901 ttttttatat agtcttgtga ttaatgttct aatcgtttta tcactaactt ctttatattt
     6961 ttgaatttca actacaattt cattagctga tactgatttt ttatcccata ttatattcat
     7021 aacatcccat tcagccatag atatttcaac ttgcttattg gtcatttaaa acacccattc
     7081 cttttaatat tttttcactt attaattcag catttttccc agacgggttt ccatctgata
     7141 aatgtgtagc aaaataatac ttatcatgat ttgtaattac gtaacctaca aaccacccat
     7201 tattatactt cccgtttact atacctgtac ctgttttccc atacagttca tacttttcat
     7261 ttttcttaat caataatgaa gaagataatt gattctttgc ttttttacta aaatggttat
     7321 tttgttccat catattttta aaaactatta cttgttcaag attagatatt ttcaaactat
     7381 cttccatcca atagctttta taacttccca aattttcatt accataattt aattgcttga
     7441 gttgagccgc agtatagttc tttggtattt gattactaat acgttcgaag taccaattaa
     7501 ctgaattttg cattgctgta tttaaatctt gttccttatt ccaagactcg aaaagataat
     7561 gtttatgatt ccatgacata cgtgaatttt tatcacttat aatatgacgg tcaagtccaa
     7621 acagtgctaa ataaattttg taagttgaat caggagaata tctttttcta ctttcttttt
     7681 cattataaat atagtatttg tctttcttca tgctgtacat aacgaaagat ccactatttg
     7741 aaccaaaatt tttactttca tctaaaattt ggtaatcgct ttgtaagggc tttttataat
     7801 tataatcagt taaggattgc cccattaaaa actggctttg aattatcatg ataaaaaaag
     7861 taaaaataca aataaaaatt agaattaatt ttgactgctt tttcagatcg gcttctttta
     7921 tattaattaa tctacttttg agtaatgatt ttttaccatt aaatgaatgg cttaatatat
     7981 ttttgttgga aaatggggtt tttaatacgg agtccataat agattccgca taagttttaa
     8041 attcattttt gttaatatta ttaaggacaa atctatcggc ttctacttca ttgtcatgaa
     8101 ttatctttct ttttacaata tgtactaatg gattgtaact cataataata gagaagatat
     8161 taaagataat taaatgtaaa gtatctctat ttttagcatg agcatattca tgcagtatta
     8221 tatattttag tcttttatca attacacttt taaaatatga actaggaatc aaaataatat
     8281 atttcccata ccaaaaagtt attggagatt gaatagcctc tgcttttcga atcacaatat
     8341 tttttttata ttgatggttg aaaagtatcg tatctatttt atttttttca ttttcgttta
     8401 gataaagtga ctgtttcttt aaatatttaa gatataataa ggctttcaaa aatttaaaac
     8461 ttaaaataat aactaaaact atccaaataa ctgtgcagat attatcaatt gaatcccaat
     8521 taaacttatg gatatctgtt gtgaactctt gaataggttt ggtggtattt atgttatggt
     8581 tcaaatcgtg tgacttactt tcaactgtgg gcgcttgatt attcacatta ttaaatttta
     8641 taaaagagaa tttaattggg ataaaaggaa ttaatccagc aagcatagtt agataccaaa
     8701 ctttataatt taaactataa ttaaaatagc gttttaatat gtacctaaaa aatactaaca
     8761 atagaaatat aaaacaaaag cttactacgc tcattattag taatttagcc attttgacac
     8821 cttctttcaa atatttataa taaacaattg acatcaatat tacaattgta atattattga
     8881 tttataaaaa ttacaactgt aatatcggag ggtttatttt gaaaaagtta atatttttaa
     8941 ttgtaattgc tttagtttta agtgcatgta attcaaacag ttcacatgcc aaagagttaa
     9001 atgatttaga aaaaaaatat aatgctcata ttggtgttta tgctttaaat actaaaagtg
     9061 gtaaggaagt aaaatttaat tcagataaga gatttgccta tgcttcgact tcaaaagcga
     9121 taaatagtgc tattttgtta gaacaagtac cttataataa gttaaataaa aaagtacata
     9181 ttaacaaaga tgatatagtt gcttattctc ctattttaga aaaatatgta ggaaaagata
     9241 tcactttaaa agaacttatt gaggcttcaa tgacatatag tgataataca gcaaacaata
     9301 aaattataaa agaaatcggt ggaatcaaaa aagttaaaca acgtctaaaa gaactaggag
     9361 ataaagtaac aaatccagtt agatatgaga tagaattaaa ttactattca ccaaagagca
     9421 aaaaagatac ttcaacgcct gctgctttcg gcaagacttt aaataaactt atcgcaaatg
     9481 gaaaattaag caaaaaaaat aaaaatttct tacttgattt aatgtttaat aataaaaacg
     9541 gagacacttt aattaaagat ggtgttccaa aagactataa ggttgctgat aaaagtggtc
     9601 aagcaataac atatgcttct agaaatgatg ttgcttttgt ttatcctaag ggccaatctg
     9661 aacctattgt tttagtcatt tttacgaata aagacaataa aagtgataag ccaaatgata
     9721 agttgataag tgaaaccgcc aagagtgtaa tgaaggaatt ttaatattct aaatgcataa
     9781 taaatactga taacatctta tagtttgtat tatattttgt attatcgttg acatgtataa
     9841 ttttgatatc aaaaactgat tttcccttta ttattttcga gatttatttt cttaattctc
     9901 tttaacaaac tagaaatatt gtatatacaa aaaatcataa ataatagatg aatagtttaa
     9961 ttataggtgt tcatcaatcg aaaaagcaac gtatcttatt taaagtgcgt tgcttttttc
    10021 tcatttataa ggttaaataa ttctcatata tcaagcaaag tgacaatagc attttacaag
    10081 tattttttat tgttcgatta gggtaaacct aaataataca taaattatat tacaatatgt
    10141 ttattataga ggctaaagta tcttagaaat ttggatagta ggtttttcgg gaataaaagt
    10201 atagttggct ttaatatata attaagctaa gctatcattt atatttactc gattataatt
    10261 cgcacttcaa cttttttata acgtaaaaat taaaacgtag ttttatttat ctttagtaat
    10321 atctttttaa acactacagt ttcttcatta gttaaattag cgaagtaatg attattaagt
    10381 tgataggctt tcttttctaa tgttggccat aagtcttttg ctttatttgt actgtttatt
    10441 agcacagttc ttctattttc attatcagtt tgacgtgtta ttagatcctt tttggacatc
    10501 ttatctaata ttccagatat tgttgaaggt tctaaattta aagtattacc aatcgcttta
    10561 ggtgtattca aattactatt aatcaagcaa ttcaaaacac catattctgc tggagtaata
    10621 ttatagggac ttaataaact tttaaaatgt ttaaaaactc tattctgaga agtactcaac
    10681 aaataattta tacaattatc taattccaca actaaaacct ctcttaaatc attagtattg
    10741 actcgcttat catatcatga taagttttgt aggaaaatag ttttgcaaca aaaacatact
    10801 tctacaaaac aattgtgaaa gaaggctaat aaatgttcaa tgcggtagta gtgagaaaaa
    10861 gtgcatcaaa tgttagttat aaagtagaaa aagttgatga atctcattta tcgaagggtg
    10921 atgtattagt aaaagtggta tactcttcaa taaattataa ggatatgcta gctttacaat
    10981 ataaaggcgg tgtaattaga gattatccta tgattcctgg tatagatttt gcaggtattg
    11041 ttgaatcaag ttcgaatgat aagtttaaag aaggcgataa tgtattagtt actggttatg
    11101 atgttggcgt gacacataca ggtggatttt cagaatatgc acaagtgcct ggagagtgga
    11161 ttgttcctat tccccaagaa atgtctatta aagagtctat ggtatatggc acagccggtt
    11221 ttacggcagc attatcaatt tttgaactag aaaaatatgg aatgaatatc aaatcacaac
    11281 ctgaaatttt agtgtctggg gctacaggtg gtgtgggcag tgttgctata caaattttac
    11341 ataaaattgg atatgaaaat atcactgcta tcgtaagaaa agaaaagcaa atagaaatcg
    11401 caaaaaaatt aggtgcaaaa caagtaataa taattgaaga tgataataaa ccgcttaaaa
    11461 aaggtatttt tgattatttc ttagatacag tggggagtaa tgtaacatta tacggtttaa
    11521 aacgtctaaa ttatcaaggt gttgctactg tatgtggaaa tgtagcagga aattcactta
    11581 acgctaatat attaccgttt attcttagag gtattaaatt aattggcatt gattctgtat
    11641 atgttgatca taatatccgt gaagatatat ggagtaagtt agcaaatgaa tggaatatag
    11701 gaaattcact tctatacaat gaaattggat ttgaagaatt ctataaaacg atagatcagc
    11761 ttttaaaagg acaacattta ggaagaacta ttttaaaagt ataagtgtga gtattcatta
    11821 atacatttac tattaattca atcattttgc atttctctac taaccagtgt tataatttat
    11881 ataacgaaaa tgattaacaa ttaatgcacc aatccccaca ctattgcagt agtgtgggga
    11941 ttttttcgat gctggcttat aaagtcgcct attaattatt tgttgcgttt actaagccaa
    12001 taagtataat acgcaacagc acagccactg atgactggtg ctatgatgtg aacgaaaatg
    12061 attagcaaag taatgcacct cctctcttcg tcaattgacg cctgagagat aggcgactct
    12121 attattatac catctgtgaa tatacaagca tatctacttc cgataagtcg tcttatgtta
    12181 tataactttg ttttttatag tatcaagaca agaagaaact cgtttcaaaa accctcatga
    12241 tttttagaga aaaactctct tatttcatcg tctttaataa aataatatgc catctttcca
    12301 tctttataaa aatcaagtac ctcattttta tataaaagcc ttaaatgatg tgaagttgaa
    12361 gcaacactca ttttcaatat caaagaaata tcacaaacac acaactcatc ttctttaatc
    12421 aaagataata tgattttcaa tttcttctca tcacaaattt tttctaaaat gttaagtaat
    12481 ttcttagatt tatcatcttc taaaaaactt aaagcattgt taactttatc ctcatgtaca
    12541 cagatcacat cacaagtatt ttcataactc atataaaatc acaccctaaa ttaaaatata
    12601 aatcctaaaa ttgtttgaat agtgtcattt tcaataataa taaataaacc taaagctata
    12661 taaataatag ccataatcca acgactaaat ttctcaacaa tttctccaat tcctggaata
    12721 ttagctaatt tttgtgcagt aaacaccaag aagaaaatta aaattaaaaa gacaaacaga
    12781 gtaagtaata aattagtaac acttaatgtc acaaaatacg gaacaaataa accaatatta
    12841 tcggcgccac aacttgctat cgtaacaatt gcaaccgtac caactaattt agacaatcct
    12901 ttttcattca attctttttt agctctcttt tctccttcac aatcatcata aatagccact
    12961 ttaattccaa gataaattgg tattaaaccc aataaaccta atatccactt ttctggaaca
    13021 taatttaata caaaagctaa aaacaaacta actaatatta aaataataga ccctaaatat
    13081 tgaccaacat aaatatctct atattctttt ctagtctttg ctctagcaaa aaatattaat
    13141 aaaattacta ataaatcaac tgctgtagca atataaagaa cagcagcagc aacaaccgtt
    13201 tgaatcataa tacacctcat tcaaaaatat ttttgaatgt attataactt atatttttaa
    13261 ataatcatag gtgctttatt ccaattgctt tattgacgtt gagcctcgga acccttaaca
    13321 atcccaaaac ttgtcgaatg gtcggcttaa tagctcacgc tatgccgaca ttcgtctgca
    13381 agtttagtta agggttcttc tcaacatcaa taaatttttt cggcataaat gcgtgtctat
    13441 gcgtagacat ggagacactt cagaattatg gagtgattac atgagtttaa ctatttttct
    13501 ttattcagtt ttaggaagtt tattagcaaa ttatatctac gaaaaatctt caaaataaat
    13561 aactttttcg gttctacttt gtacacttta tctacctggt agacctaatt gttattgctt
    13621 tacaggtcta aaattcgtcg ttataatcta gttaaatccc gtaagggcgc acttatacgt
    13681 cggataaatc gacatgtgca aaaacgtaat cgaccttcgt cgattttttt atttcaaaat
    13741 taaagaaacg gcttgagata ttccgagcag ttataaaaat taatttgcgt tgaatattgc
    13801 tactacattc ttgaaaaagt gatgtagatt tatagcccat aacttttttg aattacatcg
    13861 acgatacggc gtcgaaagaa aaataaatag accgtatgaa agaaaaagct acctcacttt
    13921 atctggggta gcttttattt tttatgccct tattttgaat tttaagaggg cattttaaag
    13981 atttaggggt gattcatata gttttatatc taaaacttat atatgctttt aaaacgcaaa
    14041 tatgagccaa ataaatatat gctattttca aaaacaaaaa tttgagcaaa aacaataact
    14101 atttttagac actgcccatt tacatgcaaa ttaaaaatta gcataaaatt ctttaaaact
    14161 tccccacgtt tttctaaatt cctgtagggc gtttttatca aaaatcaaga caagaagaaa
    14221 ctcgttcaca ctcgtttcaa aaaaacaaga aatctaatct atacacctac cgttttccaa
    14281 cccctcaaag catacaaatt aaaaacaaaa ttattcataa tcttactttc ttttaacaaa
    14341 aacataaaaa ccataaatag acaaattaac tatcaaaggc aataaacagt ataaaaaaac
    14401 cacgaataaa tcttcatcaa catctaaaat aaaaaagaat aaaacaatta acaaaatact
    14461 aattaacaaa cctaaaagtg gcaaactttt tatatatttt tctaaatttt cattcataaa
    14521 atagactcct ttcaaaaata tgtttataaa tatattaaaa taaatattga ttttataaag
    14581 cgcttactta tacaattaaa atatcttatt atcttggagg tatcaaatga aaattataaa
    14641 attattttca ataatttcct tgttcctact ggtatttagc gcgaattttt ctaatgctta
    14701 cgcaaatgaa gaacaaaaaa gttctttact agaaaatcaa aaagaaaaat tgaaaagcaa
    14761 aaacatcgaa gtatcacaaa tgaccaagaa agaaataagt tttctagaac aattgcaaaa
    14821 taaaaatgaa gatatgcaaa aattcgaaaa gcaaatgaaa aaagaaggat ttaaaaaaat
    14881 aaagctagaa gacaaaaatt ctaaattaaa atatctagct acagaagcaa atgataaaaa
    14941 tgcatatggc tacatagcta ataacgctta taaaaatgaa aaaacaaaag aaattgtagt
    15001 ttctgaaaca atatatgata actacaacaa aaaaatcaca aaattcattg ccgaaaaaag
    15061 aagtatgact gaaaacaaag agggaaaaat acttattaac aaaaattacg ttgaatataa
    15121 ggctgaaaaa gttgataaaa acagaccggt aacatatgca ggattcaaat ggaacggcaa
    15181 agcattcgct tgtagtatgg ctggacttta tgcatgtgct cactactgtg gagtatgggc
    15241 aatcgtaaat ccaatagccg gcggtgtatg tgaagcagtt tgcggaactg catttgcagc
    15301 tggatgctct gtaggttgat tttattccaa ttgttttatt gacgttgagc ctcggaaccc
    15361 ttaacaatcc caaaacttgt cgaatggtcg gcttaatagc tcacgctatg ccgacattcg
    15421 tctgcaagtt tagttaaggg ttcttctcaa catcaataaa ttttttcggc ataaatacga
    15481 tgttccttat ttatcctcat aaaaaacaat agctgaaata tataaccaat tactgtgtgt
    15541 ttgaatttct aatacatgaa tatcattctt taaaaaccta ttaacttgtt tatctaattg
    15601 acgatgagta aaagtagcga aagttttaat cttcatgata tctctccttt tataaaaata
    15661 gcaatcctta ttacaatatt aaacactttt attttggatt ttaagaggca ttttgaagac
    15721 ttagaggcaa atcatatagg ttttgtactt aaaaatctat acagtctctt aaaacgcaaa
    15781 tatgagccaa ataaatatat gctaatttca caaacaaaaa tttcagcaaa atcagtgact
    15841 aattttttag atactgccca tttacatgca aatttaaaaa ttagcataaa atactttaaa
    15901 acttccccat gtttttctaa attcctgcag ggcttttctt atcaaaaact tagaaatttt
    15961 aatttaactc taaaatctcc gtaagagcat aagggaaatt tgctatcatt caaaaatgat
    16021 agatctggca aggccagaca ttccaagggt tttaagttat tttaaagtga tatcatacaa
    16081 agctgtagtg tcacactttt gtgacactac atacagcatt tgtcacaaaa ataagacagc
    16141 acttttttac agaaaaacaa taaaaaaaga catcagttat cactaatgtc ttaaataata
    16201 attttgcttt tcgaaattcc aaattgcggt aattgaatgt gctttttttc ttcgtctgtc
    16261 gttttatctt catcacttgt attaatcaaa ttaccatctt cggcatcgtc taagtttaaa
    16321 attttatgct tttgtttaag caatccacca taacttaaca tacgttttcg atacaaacct
    16381 ttttctaaat cacttacaat ttcttgattt ttttcgtcgt catcagttaa aaagtcagat
    16441 gatttaacgg aatattttga tgtctcttcg agtgttataa aatcatttga attattgatt
    16501 aaagatatta tattgtttca tgtttttacg gcgcatataa agggcatgtg tttcttcaag
    16561 ttcagttaga attgtttgca ttaaataagc ttgcattgac ttgattgttt ccttttggcc
    16621 tttaactccc ctatcatgta tagctttttt aagtcttttt aaagaagtta atatttcatc
    16681 ctcaatgtcc tctaacatgt aatgcatatc ttcatgcctt gaattaaatg atttttttgc
    16741 tttaagaata acagccttta tgatttctaa atctctataa tcatatttta ataaataatt
    16801 agttagttgt tctgggaatt cttgcaatag catttcttta tcatcaaaat tatgtgtaaa
    16861 ttgatttgaa tgatttgaat gatttgaatg attactaatt tcatttttgt actttatatc
    16921 attcaagtca ttcatatcat tattctcagt atcattaaag tcaatgtcat taaagtcagt
    16981 atcattagtg ttcgattttc gaacttctgg acgttcgatt ttcgaacttc tggacgttcg
    17041 attttcgaac ttctggacgt tcgattttcg aacttccttc tcgccgtaag gttcaacatc
    17101 gttttcttct ttttctattt tgtaaatatc acgttctgtg acaataggtt tcattaaata
    17161 tagaatattt ggtttattta aaccacgtcg tttttgaatg agtagaccat cgttttctaa
    17221 cccttttttt atttttgtta acttttcttt tttacaattt aagatttcca ttagcttttc
    17281 atttgaataa acaaagtaaa tgttaccatc ttcatcaacc cagctatttt taatagataa
    17341 atttaagcga tcacgtaaga tagcataggc tattttcata tcattagtta gatttttata
    17401 attttcactg gtaaagaata ctttagggat ttgataaaat ctttctttgt aattttcttg
    17461 cactgtaaaa tattgatttt gcatgacaaa aaacctcttt ccatatttta gtttggtaag
    17521 aggtaataaa acgtttttat ttagctttac atttatttaa tgatttaggt gcttgcacta
    17581 agatattatt cattatataa tacaagtatc gaaaattata taaataaaca gtttctaaac
    17641 gttttattac caaaccccga ctattaccag tagttggggt ttttgttata ttaagtttat
    17701 tatagcactt taaataaact tataaaaggg aaaatatagc tttatcaagg gtttataaac
    17761 ccttgataaa tatcataaac ctttcataaa cccttgataa aaaggttgat ggatgtttat
    17821 ttttatttat taatcacttt attattaagc attataagct tataatattt tatcaagggt
    17881 ttataaacat tttataaagg gttgatgata tgaaaagtgt gaaaaagttg agtgaagaat
    17941 taggggttag taagcaaacg atttttaata atattaagcg attgaatata gagacaataa
    18001 aacaggaaaa cacttcgttt attaaagaag ataccgatat agaaaaaatc attcaaagag
    18061 taaatgaaaa taaaaagaaa tatggttttg aaagtactac tgaagacaaa caaaaaaaag
    18121 ggtcggataa tattaatttt gaatcgaaaa gcgatgctca aatagtagaa atccttaaaa
    18181 atcagattga tactttaaat aatcaaattg aaaaacaaga aagtcgtcat gaaacaacaa
    18241 ttgaatttta cagaaaagag ttgcaagaaa gatcaaaatt gcttgaaaat cagcaagttc
    18301 tggcattaga gagtaataaa aagattcaaa aattagaaaa tcaattagaa aaagaaaaac
    18361 accttaatta tccctttgat acatctacta acactagaca aaacgttgat gcacaagaaa
    18421 aaacatatac tactaatcct gtaaatatta acagagatca ggaagaaact aaagaaacag
    18481 agattcaata taaggatata tctggaagtc aaagcgacga aagtacacaa ggtgaagaag
    18541 caaaaaaaga agacgttcca gctaatctaa atgacaatga tagtgatata gaagaaaaga
    18601 gtgaagaaac ggaacctaaa aaggggtttt ggagtcgttt gtttggtagc taaaataatt
    18661 gattaggcac taaaagttat aaaattttag tgtcttttat atagtgagaa cttctggtaa
    18721 tcatcgatta tgtaaactaa agtatttcaa ataattaact gtattaatac tctcatcatg
    18781 attgcgttat aaacgttcgt tattgagaca aaatttaata gtactactac acaaaaagag
    18841 agtgcgaatt cgcactctct ttttgtgata aatgaatggt taagaaaata attcatccac
    18901 agttgtatca aacaatcttg ccaacttaaa tgctaatgtc aatgtaggat catatttatt
    18961 gttttctatt gcattaatag tttgcctaga cacttttaat tctttactta aagtttcttg
    19021 agaaattcct ttttgttttc tatattctct aattctattt ttcattaatt taacctttag
    19081 atgtatattt tttatttgta gtatagtaat taaacagcat aagaaatagt gctacaatta
    19141 taaagaaaat ttctggatat tgagaaaacc aagatccttc aatacttggt gacaaacctg
    19201 taaatttaag cactagtgta aataacatac aatatacaat ccaaataaaa cttttagcca
    19261 gtatttcaat aaacatttta cgttgtcttt catcgtatcg atcttgttgt ccttttttat
    19321 ctaatgtttc tgaaggtaaa tatttgttag ttatagccgt ccataaacaa gaaaaaatta
    19381 aaataataat aaaaggaatt aaattcatta taacacctca taaatgtaaa aagtatttga
    19441 catttatgag tgtaaatatt tttgatacaa atgtcaaata ctttttacat tataatatat
    19501 tttaaaacac cttattagta aaacaattac tatatagaaa gctgcgaact cgtactcttt
    19561 tttcttgtat aattattaaa atctcaattc aataatatgt tatggaattt gagacactgt
    19621 gagagacgct catttgcatt gacaatcaat ttatcaagat aatcccttat catgtttaat
    19681 tctataaact gtttgtcttg tgatattaac ttctttcgca atcttactaa tcgctttgcc
    19741 ttcttctaac atttccacca cgcgatgata aataacacgt ttctgtgggt ctttagcatt
    19801 tggtgaataa agtaaagggc gccctttata tacgcctttt tccttcgcaa cttgaatccc
    19861 ttgcgcttgt cgacgtttac tttcatttct ctcttgttct gaaaccattg ctaatatttg
    19921 aatgattaaa tctttcataa acttatccag taatggattg ccaattactt cattcatcat
    19981 aggtaagctg gtaatcatta actgaacgtc tttttctttt aaataattca cagtttcaat
    20041 aatttcatca tagttacgtc ctaaacgatc aatagattcc acaacgaatc gatctcccat
    20101 tctgacaaaa ttgagtgctt cttgaaatac aggtctattt tccactgact ttcccgactg
    20161 tttctctgta aagattttct ccacaccaaa cgtctttaaa ttatccaatt gtctttctaa
    20221 attttgatct atcgatgata ctctcgcata acctataatc attcatcttc actccataat
    20281 aaatatacac cctaatcata cgttttaatt gttataattt caacaattct ttttgtatgg
    20341 ttagggtgta ctcaaagtgt acatatctat aattaaaact tactaaaaat aaatatagat
    20401 tttttctttg taacagaacc gttcatttga aggtcatctc tatcataaat atttaaatta
    20461 actaaaaatt ttaatcatct gtttaatact tatgaaatgt atttacggta ggtattaaaa
    20521 ttgatgaaat ttatataagt gctttcaatg aaaatgaccg tttatttatc ctcctgattt
    20581 aaggagttag aaatttcgaa aacgattctt tccatttgtt gcatttgttc catgtccaga
    20641 tatttaatac attatagaaa accaaagacc atcactaatt aaacgcagtt ttaaaatttc
    20701 atcaggattg ccttcgtctt taaaatgggc ctcttttaat ataagttcta ctctttcata
    20761 cctaactctt tcaatgccat cgtttcatac gccgattctc ctgattccat agcaaactca
    20821 gcgataaaca ttgggaatac tgcattgagt tctattatat gctctttcat tcgtggccat
    20881 atttcacctc cagctttacc gtatgctgtt ataagttgct ctaatccttc gtcgtcgaat
    20941 acacgatggt gtcctataaa gtccattgat gggtcggagt gggttgcttc agtccagtct
    21001 atgagacctg tgacgtttgc ttggttatct accattatat gtcctggatg taagtcccca
    21061 tgtatcatgg tcgcatgtcg aggccatagt tcgtcgtttt ctaaccattg tttccatctg
    21121 ttccataatt catctgatac gccataagtt tctttaactt tattcattct tctttgaaag
    21181 tcatttttta tttcttgtat ggttttgata tttatatgct gaacgttaat gttttcttct
    21241 ggtatgttgt gtaaatctac gagtgtttca gctaatgtgt taataaagtt ttctggtaat
    21301 ggtttgtgtt caatttccca tacataattt tgtatttctg gatctattgt ggctgcgggt
    21361 ttacctgtaa gttttgggta agcaataagg tcttttgcat gtactttcca cttcggtatt
    21421 tcaaatgaaa cattcttctg taagaagtct accgtttgtt tttcgggttt tgttcgttta
    21481 taaacgtcag gtcttcttgg tagtctcaaa acccattcta ctccatgttt atcttttcca
    21541 aatgcaactt gaaaatcaag tcccgattca ttcaatgaga ttgtttgagg ttggatgtgt
    21601 aattgatatt tttctgcaca tttaataatt tcattatgtc gagtcatttt attggatcct
    21661 tatttctatt atatttttct tgtgaacgta ttttttatat tgatataaat gaacctaata
    21721 ttcaatataa attagtgtat agtttttaag ttatatcatg aagagattgt cctgttaatt
    21781 cccatttttt atctgataca tgtttaacaa accttgtatc atgtgatgta aacaaaatga
    21841 ttccaggata tttattcata aacatttcta atgcttctaa tgttttaata tctaaaaaat
    21901 tagttggttc atccaaaatt aacatattcg ctttcgttga aaataatact gctaacgata
    21961 atttcgttct ttccccacca ctcaaaacat tacaagaacg atcaagtgct tcatttaaac
    22021 ccaagttatt taaaatagct ctactgaatg attctgatga atcgtttcat ccattaaata
    22081 ttgcaataat gaaacgtcac gcatgtcttc ataagcaagt tgacgatagt atgccatttg
    22141 cactttagga gaacaatcaa ttcctctatt tggtggtaaa tagcttcaag taaagttgtc
    22201 ttacctacac catttgcacc tacgagcgct atatttttgc catatggtat ttggaatcgt
    22261 acttgtgtta gcagtttttg acttccttta accaatgtta gattttgtgc aatgattgga
    22321 taattattat ggatatcata aattttattt tgtggaaatt gaattcatga taactttgtg
    22381 gtttttcaac ttcttcaaat gttccattct tttttcaata tgcttagctt gtttttgagc
    22441 agccttctca acctgtgctt tttgttttga tgcacttaaa cgatctggtg ctatactttt
    22501 gtttttttgt tttgatgatg cttgtgccat ttgttgcgct tgatttcgtt tagctttact
    22561 ggcttgggac aatctttgtt tttcacttat atactgttca tattgacgtt gttgttctaa
    22621 ctgttcttgt tcatattgat tttgatactg tgtgtaatta cctttaaaca ctcttattgt
    22681 gccatcttct tgtatatccc aaattgtgtc agcaatttgg tctataagtg ctctatcatg
    22741 acttactata attaaagtac catagtaata ttttaaaata tttttcagat aatctttacc
    22801 aattttatcc aagtgatttg taggttcatc taaaagtaat atcggactat aatttgatat
    22861 gacattagct aatttatatt ttgctttttc accaccactc atactgtcgg ttgtatgcat
    22921 aggtatatgg agttcactca ttaaactacc gtctaacgtg tttaaaatca ttttccaccc
    22981 atgttaagct gt
//
