LOCUS       CP043371               10060 bp    DNA     circular BCT 14-MAR-2022
DEFINITION  Klebsiella pneumoniae strain WCHKP090050 plasmid p1_090050, complete
            sequence.
ACCESSION   CP043371
VERSION     CP043371.1
DBLINK      BioProject: PRJNA353728
            BioSample: SAMN09842417
KEYWORDS    .
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 10060)
  AUTHORS   Wei,L., Long,H., Feng,Y. and Zong,Z.
  TITLE     The complete genome of Klebsiella pneumoniae strain WCHKP090050
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 10060)
  AUTHORS   Wei,L., Long,H., Feng,Y. and Zong,Z.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-AUG-2019) Center of Infectious Diseases, West China
            Hospital, Sichuan University, Guoxuexiang 37, Chengdu, Sichuan
            610041, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.7
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology :: Illumina HiSeq; Oxford Nanopore MiniION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/27/2019 13:20:26
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region
            Annotation Software revision      :: 4.9
            Genes (total)                     :: 5,727
            CDSs (total)                      :: 5,605
            Genes (coding)                    :: 5,460
            CDSs (with protein)               :: 5,460
            Genes (RNA)                       :: 122
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 11
            Pseudo Genes (total)              :: 145
            CDSs (without protein)            :: 145
            Pseudo Genes (ambiguous residues) :: 0 of 145
            Pseudo Genes (frameshifted)       :: 47 of 145
            Pseudo Genes (incomplete)         :: 95 of 145
            Pseudo Genes (internal stop)      :: 26 of 145
            Pseudo Genes (multiple problems)  :: 20 of 145
            ##Genome-Annotation-Data-END##
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..10060
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="WCHKP090050"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="p1_090050"
                     /geo_loc_name="China: Chengdu, Sichuan"
                     /collection_date="2018"
     gene            join(9825..10060,1..70)
                     /locus_tag="D0S94_28525"
     CDS             join(9825..10060,1..70)
                     /locus_tag="D0S94_28525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UNC79634.1"
                     /translation="MLDAPDEAAKLLLILRVVSRSLWRTLTGAGTPEKTALGCRLFLSH
                     AGACSLFLRGCAFSAWGGKRLASAVKAERNHHGRDRRRHALGHVRGLCSGGCASRR"
                     /name="hypothetical protein"
     gene            98..2062
                     /locus_tag="D0S94_28530"
     CDS             98..2062
                     /locus_tag="D0S94_28530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008321411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="UNC79621.1"
                     /translation="MFNTDSLAWQWHIPELARQIYPWVSWLYREYYSLAGFFLVIGLFF
                     GLAELWAGRMRFVGLSHKARREYADRYKRDNNRTVPFSVLASLDSPGRMVRARRHVWNY
                     AYWLTGAAGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLV
                     AGVLLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNA
                     LADFSTEQARKQQAVFLGKDEQGQPVLVPRDTWRKTNIQILGLPGSGKSAMATNALIRC
                     VRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLV
                     AGFNLSETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLIT
                     KLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARD
                     EFRRWPHASIMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPADFV
                     KTTVLDNTPIRWFYRAASQESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQK
                     EARPLFDVNTLQHLPDGFAVMTGLGVARLAFSSPLRVERREISLKTFPVLAKTDPLAEY
                     LPPADGGGPKADDDFAGLY"
                     /name="TraM recognition domain-containing protein"
     gene            2062..2793
                     /locus_tag="D0S94_28535"
     CDS             2062..2793
                     /locus_tag="D0S94_28535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UNC79622.1"
                     /translation="MTLEQYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRAKYPVDGRQVSVWGLTPHGVAFSFDEDEPLTDVIPFQP
                     SRVSAAQLPHRLAVQSLRLSMEGRGATGWRYLHRMALKGMKVPDALAELDGRTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRRANGIDEIWYICPDRPTLVRVQRAILAVDEIVNPQTGEA
                     RKTVELDRERLFACFKFMTTE"
                     /name="hypothetical protein"
     gene            2800..3330
                     /locus_tag="D0S94_28540"
     CDS             2800..3330
                     /locus_tag="D0S94_28540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008321413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UNC79623.1"
                     /translation="MALYMVFIEDVEDKDGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGENPQWERDKPTGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQINAMIEVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
                     /name="hypothetical protein"
     gene            complement(3357..3536)
                     /locus_tag="D0S94_28545"
     CDS             complement(3357..3536)
                     /locus_tag="D0S94_28545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="UNC79624.1"
                     /translation="MTKQEKTALNMAKFIKDQSLLLLEKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            complement(3562..3990)
                     /locus_tag="D0S94_28550"
     CDS             complement(3562..3990)
                     /locus_tag="D0S94_28550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UNC79625.1"
                     /translation="MAKTLLNLSQAAQAAGITRRTLYNHVKQGKVTVSRDGKNNPVVDV
                     SELIRVYGNVNIPEKQIPGISHRENTQKNFPQEQLLAMQKELADLRQAVTLMLEDKTSR
                     EEERRQHDDERRKLQAEVDRLTTELTQKKKRFWSGWFS"
                     /name="hypothetical protein"
     gene            complement(4154..4468)
                     /locus_tag="D0S94_28555"
     CDS             complement(4154..4468)
                     /locus_tag="D0S94_28555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="UNC79626.1"
                     /translation="MPQVTISALAQRDLQRLQDFLKTKNRLAARKGGEVIVRAIQQLKT
                     LPDIGRPVPFLPLEYKELVIGFGDSGYVMLYRHDREMDQIVIVTVRHQKESGYPGADSL
                     "
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(4456..4734)
                     /locus_tag="D0S94_28560"
     CDS             complement(4456..4734)
                     /locus_tag="D0S94_28560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019952150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="UNC79627.1"
                     /translation="MSSATSIRLDEELKDRLKTLADDRHRSAHALMLEAITEYIDREEK
                     RSQYLRDGQAAWQHYQETGLHLTAEEAEAWISTWGTENEQDAPPCHR"
                     /name="ribbon-helix-helix protein, CopG family"
     gene            complement(4909..5274)
                     /locus_tag="D0S94_28565"
     CDS             complement(4909..5274)
                     /locus_tag="D0S94_28565"
                     /inference="COORDINATES: protein motif:HMM:TIGR01352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB family protein"
                     /protein_id="UNC79628.1"
                     /translation="MKAFTLTVLAAMFLTPVHAIPLKPVTTLQPTYPVQAAAKRIEGQV
                     TATFDILDDGRVDNVSLTGCHLFFRETLTAMRHWLYPAGHPAMRQVINFEFSLKNDGLQ
                     DPRPVTTQKLNDDGCRQ"
                     /name="TonB family protein"
     gene            complement(5271..5642)
                     /gene="tolA"
                     /locus_tag="D0S94_28570"
     CDS             complement(5271..5642)
                     /gene="tolA"
                     /locus_tag="D0S94_28570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope integrity protein TolA"
                     /protein_id="UNC79629.1"
                     /translation="MRLIPFILLALCSPLLLTACKHSTTQPPKIYTLDKSSKISSYAAA
                     IKTAVEMQMFEPEAYAGKMCTVRISIQRDGTLNSAIAEGGDPKLCKAAISAVTHAKIPP
                     APDENTWQIFKNAPLDFRP"
                     /name="tolA"
     gene            complement(5916..6161)
                     /locus_tag="D0S94_28575"
     CDS             complement(5916..6161)
                     /locus_tag="D0S94_28575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="UNC79630.1"
                     /translation="MTHLKLTPAEEKRLADAFVAQALAMGLKGNKTLPKAVKQQVRERV
                     LRAIQDEREARRAQEMRREKYEATETTFTWQPQRRR"
                     /name="hypothetical protein"
     gene            6488..8173
                     /locus_tag="D0S94_28580"
     CDS             6488..8173
                     /locus_tag="D0S94_28580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cloacin"
                     /protein_id="UNC79631.1"
                     /translation="MSGGDGRGPGNSGLGHNGGQASGNVNGTSGKGGPSSGGGTDPNSG
                     PGWGTTHTPNGDIHNYNPGEFGNGGSKPGGNGGNSGNHSGSSGGGQSSATAMAFGLPAL
                     ATPGAEGLALSVSGDALSAAVADVLAALKGPFKFGLWGIAIYGVLPSEIAKDDPKMMSK
                     IMTSLPADAVTETPASTLPLDQATVRVRQRVVDVVKDERQHIAVVAGRPMSVPVVDAKP
                     TKRPGVFSVSIPGLPSLQVSVPKGVPTAKAPPKGIVAEKGDSRPAGFTAGGNSREAVIR
                     FPKETGQKPVYVSVTDVLTPAQVKQRQEEEKRRQQAWDAAHPEEGLKRDYDKAKAELDA
                     EDKNIATLNSRIASTEKALPGARAAVQEADKKVKEAEANKDDFVTYNPPHEYGSGWQDQ
                     VRYLDKDIQNQNEKLKAAQASLNAMNESLSRDKAALTGAMESRKQKEKKAKDAENKLNE
                     EKNKPRKGTKDYGHDYHPVPKTEDIKGLGELKRGDPKTPKQGGGGKRARWYGDKKRKIY
                     EWDSQHGELEGYRASDGEHLGAFDPKTGKQVKGPDPKRNIKKYL"
                     /name="cloacin"
     gene            8183..8440
                     /locus_tag="D0S94_28585"
     CDS             8183..8440
                     /locus_tag="D0S94_28585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cloacin"
                     /protein_id="UNC79632.1"
                     /translation="MGLKLRLTWFDKKTEEFKGEEYSKDFGDDGSVIESLGMPLKDNIN
                     NGEFDLKKEWVPLLQPFFKNQIKPDVDNCYIAFDYRDGNW"
                     /name="cloacin"
     gene            8525..8674
                     /locus_tag="D0S94_28590"
     CDS             8525..8674
                     /locus_tag="D0S94_28590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysis protein"
                     /protein_id="UNC79633.1"
                     /translation="MKKVKTIFLFILIVAGFLLAACQANYIRDVQGGTVAPSSSSELTG
                     IAVQ"
                     /name="lysis protein"
     BGC             1488..10060
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          complement(8778..9356)
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="98.282"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          2063..2790
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="93.416"
                     /coverage="100.0"
                     /evalue="1.34e-140"
ORIGIN
        1 tgaccgccgc cgccatgcct tggggcatgt ccgcggcttg tgcagcgggg gctgcgcatc
       61 acgccggtaa acccgtcgtc tgaaggagag agattgcatg tttaatacgg attcgcttgc
      121 ctggcagtgg catatcccgg agctggcccg gcagatttac ccgtgggtca gctggctgta
      181 ccgggagtat tacagtctgg ccggtttttt tctggttatc ggcctgtttt tcggtctggc
      241 tgaactctgg gccggccgaa tgcgttttgt ggggctgagc cataaggcgc ggcgggagta
      301 tgccgatcgc tataagcgcg ataataaccg gactgtgcca ttttcggtgc tggcctcgct
      361 ggattcaccc gggcggatgg tcagggcacg gcgacatgtc tggaactacg cgtactggct
      421 gaccggcgct gccggtctgg cccttctggg ggggctggtt gtcgccgtgt ttatcgagag
      481 ctggggagaa accgtcctgc gcccggacct ctatgcgaac gcagattatt acctgctgca
      541 gccggctaac ctgttcggga tagcctggtg tgccggaggg cttgtcgccg gcgtccttct
      601 ggcgcggctg ctggcgttcc tgctgcttga tggtcatttt gcggccgctg acgaggcggt
      661 gaacgcgaaa ctgaatcagg agagccggcg cagcagccag cggaccggag aaatgacaga
      721 cgtccgccac ctgcatttcg gggagccggt accggttaac gcgctggccg atttttccac
      781 ggagcaggcc cggaaacagc aggcggtgtt tctgggtaag gatgagcagg gccagccggt
      841 gctggtccct cgtgatacct ggcgcaagac caatattcag atcctcggcc tgcccgggag
      901 cggcaagagc gcgatggcca ccaacgcgct cattcgctgc gtacgcgatt tcggggacgc
      961 tgtggtgtac ttcgacccca aaggggacgc gtgggcgccg cacgtcttcc gggcgcactg
     1021 cccggacttc accctgctgg atctgcggcc ggggaaaccg gcgcagctga atctgttccg
     1081 cgatctcgac cagtacgccc tgaagaatct gctggttgcc gggtttaacc tgagtgagac
     1141 cggcgacgtg gcggaccact accgcatcag cgagcagaaa gcggcgaagc tgattgcgga
     1201 gcagttcccg cagggggcaa acattcagca ggtgctggcg gcggcgtacg cgttgccgga
     1261 ggccctgaaa aaggacgtga aggggctgat caccaagctg gagaacgtgg ccgacctgag
     1321 cgtcctgcag acggacagcg gtatcgatgt ggcggggata atcaacggcg gcggctgcct
     1381 gtacgtcatc ggctcgatgg acgatgaggc ggtgatccgg gtgcagaaga tgctgtttgc
     1441 ccgctgcgcg caaatcatca ttgcgcggga tgagttccgg aggtggccgc acgcgagcat
     1501 catgctcgat gagattaaat atctgctgtc gaagtacgtg ctgaacgcgc tggggacgct
     1561 gcgcagccgg gactgcaacc tgctgctcgc gcaccagtcg ctgggcgact tcggtcagtg
     1621 cgggcaggat ctgcccgctg attttgtgaa aaccacggta ctggataaca cgccgatccg
     1681 ctggttctat cgcgcggcca gccaggagtc cgcgcagtgg gcggcgggcc agaccgggga
     1741 gatccgggtg gacgtggagc gccgccgggc cagccgggag gcggggaacg tggagcacat
     1801 cagcggcgac agcttcatcc agaaggaggc gcggccgctg tttgacgtga acaccctgca
     1861 acacctgcct gacgggttcg cggtgatgac cgggctgggc gtggcgcggc tggcgttcag
     1921 cagcccgctg cgggttgagc gccgggaaat ttcgctgaaa accttcccgg tgctggcgaa
     1981 aacggacccg ctggcggagt acctgcctcc ggccgacggc ggcggaccaa aagcggatga
     2041 tgattttgcg gggctttact gatgacactg gagcagtaca acgtcagcca cgcgaagcgg
     2101 caggcgcgga acgcggagaa aacacggctg accctgcgct ggctgcggga agagctgtgt
     2161 tccacggcgg agctggttgc gcgacggctg gggattgcgg cggtacagcc ggtttaccgc
     2221 ttcctggaca gtctggtggc gaaagggctg ctggtccggg cgaaataccc ggttgacggc
     2281 cgtcaggtca gcgtgtgggg gctgacgccg cacggggtgg cgttctcgtt cgacgaggac
     2341 gagccgctga cggacgttat tccgtttcag ccgtcaaggg tgtcggcggc gcagctgccg
     2401 caccggctgg ccgtgcagtc cctgcgcctc tccatggagg gccggggggc caccggctgg
     2461 cggtacctgc accgtatggc cctgaaaggg atgaaagtgc cggacgcgct ggcggagctg
     2521 gacggcagaa cggtggcatt tgaggtagag cgcaccgtca agagccgcag gcggtatcag
     2581 gaagtggtgt ccgggtatct gttcaaccgc cgggcgaacg gcatcgatga aatctggtac
     2641 atctgccctg accggccgac gcttgtccgg gtacagcggg cgattctggc ggtggatgaa
     2701 atcgtgaatc cacagaccgg cgaggcccgc aaaacggtgg agctggaccg ggagaggctg
     2761 ttcgcgtgct ttaaatttat gacaacggag tgagggatta tggcgctgta catggtattt
     2821 attgaggacg tggaagacaa agacggcgag cgctgcatta tgccaaccag cgagcatctg
     2881 gaagacatgg tggtgctcgc ctggcagacc ggggcgtatg ttttctgttt tgtcgaccgg
     2941 gcccagcatc tggcgatgat gaaatccatc gggatgtatg acgagcggct caacagcgac
     3001 gaaaaagcca cgtacttttt caccggtgaa aatccgcaat gggaacggga caaacccaca
     3061 ggaatgaagc tgtgtgatta cctctatcga aaggtggagc ggttcgccat cgagaacggt
     3121 gtgcaggtgg ttgatgccgg gaagtgctca ccggagcaga ttaacgcgat gattgaggtg
     3181 gtcagcgagc ggcacgggga aagcgcggtg aacgagaagc tgaaagcgga gctgatgcgg
     3241 gaatataaca gccgctattt taacgtgccg gtgcctgaac tgccggagga caaacccgcc
     3301 cgccggtggt ggccgttcgg caaaaaataa cgccagcacc ggcatggccg gtgctgttat
     3361 tcttccccga gcttatcccg catcacctgc cagagtgttt ccgcatcctc gtgaagccgt
     3421 tcgcacatgt cggccggggt atccatgtcc agctcgttca gcttttccag caacagcagc
     3481 gactgatcct taatgaattt agccatattg agggcagttt tttcctgctt cgtcatgttc
     3541 tccattccct tcggtaagtt ctcagctaaa ccagccggac cagaagcgtt ttttcttctg
     3601 tgtcagttct gttgtcaatc tgtccacttc ggcctggagt ttccggcgct catcatcgtg
     3661 ctggcggcgt tcttcttccc gggatgtttt atcttccagc atcagggtga cagcctgccg
     3721 gagatcggcc agttcctttt gcattgccag aagctgttcc tgtgggaaat ttttttgtgt
     3781 attttcacgg tgtgaaatgc cgggaatttg tttctcaggg atattcacat ttccgtatac
     3841 acggatcagt tctgacacat ccacgacagg gttgtttttc ccgtcacgtg acacggtaac
     3901 ctttccctgt tttacatgat tgtatagcgt tcttctggta atgcccgcgg cttgtgctgc
     3961 ctgtgaaagg ttgagcaatg ttttcgccac tgtatacccc tgattttatc gggtgtgaaa
     4021 ggtgtgtaat ttctcacggt aaatgtatcg ctgaatttta cccgtttttc cgttcaggat
     4081 gtggttttct gacgcgctgc gcttgtcaaa ccggcgacgg ccacgcaatg aattgcgccc
     4141 ccgtcatcgg ttattagagg ctgtctgccc ccggataccc ggattctttc tgatgcctga
     4201 cggtgacgat cacaatctgg tccatttccc ggtcgtggcg gtagagcatc acatagccac
     4261 tgtcgccaaa cccgatcacc agttccttat attccagcgg cagaaacggc accgggcggc
     4321 caatgtctgg caatgttttc agttgctgga tagcccggac gatcacctca cctccttttc
     4381 tggctgccag ccgatttttg gttttgagaa agtcctgaag gcgttgtaaa tcgcgctgtg
     4441 ccagcgcgga aatcgttacc tgtggcatgg cggagcatcc tgctcgttct cagttcccca
     4501 ggtacttatc caggcttccg cttcttccgc agtaaggtgc agacccgttt cctgatagtg
     4561 ctgccatgcg gcctgtccgt cccgcaggta ctggctgcgc ttctcttccc ggtcgatgta
     4621 ttcggtgatt gcctccagca ttagcgcgtg cgctgagcgg tgccggtcat cggccagcgt
     4681 tttcagccgg tccttaagtt cttcatcgag cctgatggat gttgctgatg acataaaagc
     4741 ccctttgtag tcatatgtat tacacatgac tactttaatc cgtggcggcg ctatttgcca
     4801 gaaatacggc ttttgctgcc catttttcag cttcgcttcc actaatcagg gctgctacag
     4861 gctcactcat catccaggac tattgcagcc tgcgggttaa aggacctgtt actggcggca
     4921 accatcatca ttgagctttt gggtggtgac tggtcgcgga tcctgtaagc cgtcattttt
     4981 cagactgaat tcaaaattta taacctgtcg cattgccggg tgccctgcgg gatatagcca
     5041 gtgcctcatt gccgtcagcg tttcccgaaa aaaaaggtga cagccggtaa gcgacacgtt
     5101 gtccactcgt ccatcgtcca gaatatcaaa cgtggcggtc acctgacctt cgatgcgttt
     5161 tgctgcggcc tgtaccgggt aggttggctg cagtgtggtt acgggtttta gtggtatcgc
     5221 atgtaccgga gtgaggaaca tggccgccag cactgtcaga gtaaaagctt tcatggtctg
     5281 aaatccagag gggcgttttt gaatatttgc caggtatttt catccggtgc cggcggaatt
     5341 ttggcgtggg taacggctga tattgctgct ttacagagtt tcggatctcc tccttcagca
     5401 atggcgctgt tcagagtgcc atcacgttgt atggatatcc gcacggtgca catttttccc
     5461 gcataggcct ctggttcaaa catctgcatt tcaacagcgg tcttgatggc cgcagcgtag
     5521 ctactgattt tagatgactt atccagagta taaattttcg gcggctgggt ggtggaatgc
     5581 ttacaggccg tcaggagtaa ggggctgcac aatgccagca ggataaaggg tattaaacgc
     5641 atcgggttga tgacctgtca gtaaaaaatg ttacatgtat atttgtcact ctttacggcc
     5701 acgttcattt acataaacac ggcttatcgt atcgttttta caccaaacgg cccgccatgc
     5761 agttgcgtgc ataggcatgc agcgggttac aatttaccgg gcgcgtttcc ggcggttttc
     5821 cgggtggttt gttgcctgtt ttatcccgta gccgccggaa acgccctcag accgtctgag
     5881 cggtgcgggc aatgcgacgt tatggtaaat accccttacc ggcggcgctg tggctgccag
     5941 gtgaaggtgg tttccgtagc ctcgtatttc tcccgacgca tttcctgcgc ccgcctggct
     6001 tcacgttcgt cctgaatggc acgaagcacc ctttcccgca cctgttgttt taccgccttt
     6061 ggcagcgttt tgttcccttt caggcccatg gccagtgcct gagcgacaaa ggcgtccgcc
     6121 aggcgctttt cttcagcggg agtcagtttc aggtgcgtca tagtggcctc cgggcgtctc
     6181 aggtttcccg aacagtttaa ccgcaggtcc tctcctcatg ccagttagct ttcagatgtg
     6241 tctataccat ctgaaatgta agtgtgatga atgtcttaaa taataaaatt tgttgccatg
     6301 agaaattttc gggaaaagac gcgatctgct tacaggtggc tccgggcgct tttttgtgcc
     6361 tgaagatgag aactaatctc atatattgac acctgaaaac gggaggagta aggtaataat
     6421 tatactgtgt atatgtacag tatgttggct ttaatttatt gttttaaatg tcaaagagga
     6481 aaacggtatg agtggtggag acggtcgagg tccgggtaat tcaggtctgg gacataatgg
     6541 tggtcaggcc agtgggaatg tgaacggtac gtctggtaaa ggtggccctt catcaggtgg
     6601 tggtacggat ccaaacagcg ggccgggctg gggtacgacg catacgccga atggagatat
     6661 tcataactat aatccggggg agtttggtaa cggcgggagt aaacccggtg gtaatggtgg
     6721 taacagcggc aatcatagcg gtagctctgg tggcggacag tcttcggcca ctgcgatggc
     6781 cttcggtctg cctgccctgg ctactccggg ggctgaagga ctggctttat cagtttccgg
     6841 cgatgcgttg tcggccgccg ttgctgatgt gctggctgcc ctgaaggggc cgtttaagtt
     6901 tggtctgtgg gggattgcga tctacggtgt gctgccttct gagattgcaa aagatgatcc
     6961 gaaaatgatg tcaaaaatta tgacgtcatt accggccgat gcggtgacgg agactccggc
     7021 aagtacttta ccactggacc aggcgacggt tcgtgtcaga caacgggttg tggatgtggt
     7081 gaaggatgag cggcagcata ttgcggttgt cgcaggtcgg ccaatgagtg tccctgtggt
     7141 ggatgcgaaa ccgacaaaac gtccgggggt attcagtgtg tcgattccgg gtctcccgtc
     7201 tctgcaggtg agcgtaccga aaggtgttcc gacagcgaaa gccccgccaa aaggcattgt
     7261 tgctgaaaaa ggtgattcac gtccggctgg ttttacagcc ggtggtaact cccgtgaggc
     7321 cgttattcgt ttcccgaaag agaccggaca gaagccggtt tatgtgtcgg tgacagatgt
     7381 tcttaccccg gcacaggtaa aacagcgtca ggaggaagaa aagcgtcgcc agcaggcatg
     7441 ggacgccgct catccggaag aggggctgaa aagagactat gataaagcga aagctgagct
     7501 ggatgccgaa gataaaaata ttgcgacctt aaacagccgc attgcatcga cagagaaggc
     7561 gctccccggt gcaagggctg ctgttcagga agccgataaa aaggtaaaag aggcagaggc
     7621 aaataaagat gattttgtga cttataaccc gcctcatgaa tatggctccg ggtggcagga
     7681 tcaggttcgc tatcttgata aggatattca gaatcagaat gagaaattaa aagcggctca
     7741 ggcatcttta aacgcaatga atgaatcctt atccagagat aaggctgcac ttaccggggc
     7801 gatggagagc cggaaacaaa aggagaaaaa agcgaaggat gcagaaaata agttaaatga
     7861 ggaaaagaac aagcctcgca aggggactaa agactacggc catgattatc atccagtacc
     7921 taaaacagaa gacataaagg gacttggaga gttaaagcga ggtgatccta aaacacctaa
     7981 acaaggtggt ggtggtaagc gggcccgatg gtatggcgat aaaaaacgta aaatttatga
     8041 atgggattcc cagcacggtg agcttgaagg gtatcgtgcc agtgatggcg aacacctagg
     8101 cgcatttgat cccaaaacgg gtaagcaggt taaagggcca gatccaaaac ggaacattaa
     8161 aaaatatctt tgagaggtaa atatggggct taaattacgt ttgacatggt ttgataagaa
     8221 aactgaagag tttaaagggg aagagtattc taaagacttt ggtgacgatg gttctgtcat
     8281 tgaaagcttg ggaatgcctt taaaggataa tattaataat ggtgagtttg atttgaagaa
     8341 agaatgggtt cctttactac agccattttt taaaaatcaa ataaaacctg atgtggataa
     8401 ttgttatata gcttttgatt atcgggacgg taactggtaa caaaaaatta tcaaggatga
     8461 tttgaaatac tgacttccgg tgttcaggga tgaatgccgg agtctttaaa tacagggaaa
     8521 gtatatgaaa aaggtaaaga ctatttttct ttttatattg attgttgctg gctttcttct
     8581 ggccgcatgt caggcaaatt atatccggga tgttcagggc ggaacggtgg caccatcgtc
     8641 ctcctctgaa ctgacgggga tcgcggttca gtagaaaaga tcaaaggatc ttcttgagat
     8701 cctttttttc tgcgcgtaat cttttgccct gtaaacgaaa aaaccacctg gggaggtggt
     8761 ttgatcgaag gttaagtcag ttggggaact gcttaaccgt ggtaactggc tttcgcagag
     8821 cacagcaacc aaatctgtcc ttccagtgta gccggacttt ggcgcacact tcaagagcaa
     8881 ccgcgtgttt agctaaacaa atcctctgcg aactcccagt taccaatggc tgctgccagt
     8941 ggcgttttgc gtgctttccc gggttggact caagtgaaca gttaccggat aaggcgcagc
     9001 agtcgggctg aacggggagt tcttgcttac agcccagctt ggagcgaacg acctacaccg
     9061 agccgagata ccagtgtgtg agctatgaga aagcgccaca cttcccgcaa gggagaacgg
     9121 cggacaggta tccggtaaac ggcagggtcg gaacaggaga gcgcaagagg gagcgaccta
     9181 ccggaaacgg tggggatctt taagtcctgt cgggtttcgc ccgtactgtc agattcatgg
     9241 ttgagcctca cggctcccac agatgcaccg aaaaagcgtc tgtttatgtg aactctggca
     9301 ggagggcgga gcctatggaa aaacgccacc ggcgcggccc tgccgttttg cctcacatgt
     9361 tagtcccctg cttatccacg gaatctgtgg gtaactttgt atgtgtccgc agcgcccgcc
     9421 gcagtctcac gcccggagcg tagcgaccga gtgagcgagg aggcgcaatt tccccggcac
     9481 ctgcaagacg gtcaccggac gcgctgatgt gggatattgt cccctgatta agtctttcta
     9541 ttccctgacg atcaattatc aggataggtg aaccatgtcg gtttttcgct gaacatttta
     9601 cgttaaccta tctctgttgc ttttttctcc ttgcggagaa atgcaagtca tccccgctgg
     9661 ggcgtggctg acttcagggg aaaagacctt gcttacgctg gctggacgcc accgacgcac
     9721 ggtcttttcc cctctttctg gctctgtccg gctggacgcc ggccacgcca gaaattcacc
     9781 cggcccccgt caggctcacg cctgaccacc cacaaaaatc cacggtgctg gacgcacctg
     9841 acgaagcagc aaagctgctc ctgattttgc gggtggtcag ccgctcgcta tggcgaactc
     9901 tgacgggggc cggaacaccg gaaaagaccg cactggggtg ccgccttttc ctctcacacg
     9961 ctggggcgtg ctcgttgttc ctccggggct gcgccttttc cgcatggggc ggaaagaggc
    10021 tggcctccgc ggtgaaagct gaacgcaatc accacggacg
//
