LOCUS       CP038005               11970 bp    DNA     circular BCT 26-MAR-2019
DEFINITION  Klebsiella pneumoniae strain SCKP020009 plasmid p1_020009, complete
            sequence.
ACCESSION   CP038005
VERSION     CP038005.1
DBLINK      BioProject: PRJNA353728
            BioSample: SAMN08624603
KEYWORDS    .
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 11970)
  AUTHORS   Liu,L., Long,H., Feng,Y. and Zong,Z.
  TITLE     The complete genome of Klebsiella pneumoniae strain SCKP020009
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 11970)
  AUTHORS   Liu,L., Lin,J., Tang,G., Yang,B., Feng,Y. and Zong,Z.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-FEB-2018) Center of Infectious Diseases, West China
            Hospital, Sichuan University, Guoxuexiang 37, Chengdu, Sichuan
            610041, China
REFERENCE   3  (bases 1 to 11970)
  AUTHORS   Liu,L., Long,H., Feng,Y. and Zong,Z.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-MAR-2019) Center of Infectious Diseases, West China
            Hospital, Sichuan University, Guoxuexiang 37, Chengdu 610041, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.7
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology :: Illumina HiSeq; Oxford Nanopore MiniION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 03/20/2019 03:58:39
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 4.8
            Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region
            Genes (total)                     :: 6,012
            CDSs (total)                      :: 5,890
            Genes (coding)                    :: 5,678
            CDSs (with protein)               :: 5,678
            Genes (RNA)                       :: 122
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 85
            ncRNAs                            :: 12
            Pseudo Genes (total)              :: 212
            CDSs (without protein)            :: 212
            Pseudo Genes (ambiguous residues) :: 0 of 212
            Pseudo Genes (frameshifted)       :: 78 of 212
            Pseudo Genes (incomplete)         :: 139 of 212
            Pseudo Genes (internal stop)      :: 35 of 212
            Pseudo Genes (multiple problems)  :: 34 of 212
            ##Genome-Annotation-Data-END##
            Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..11970
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="SCKP020009"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="p1_020009"
                     /geo_loc_name="China: Bazhong, Sichuan"
                     /collection_date="2016-09-30"
     gene            261..512
                     /locus_tag="C6L86_29945"
     CDS             261..512
                     /locus_tag="C6L86_29945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012600009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QBQ33801.1"
                     /translation="MTGVLTGQPLSHEMYIKLPGADVVLLTEGNIIGCDTASATWTRRG
                     LRPWHVNTISTREPGDLPSDHLPVSEMARTGKTRSHSR"
                     /name="hypothetical protein"
     gene            512..1996
                     /gene="ltrA"
                     /locus_tag="C6L86_29950"
     CDS             512..1996
                     /gene="ltrA"
                     /locus_tag="C6L86_29950"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004152765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="QBQ33816.1"
                     /translation="MYGEEKSDSLIVAAKQANNPKGAESVERRSGAKGNAEQPHMRRTQ
                     SRESMSQRLSRVREAAKQRKKERFTALFHLLTVEALEAAFLSLSRKAAAGVDGIRWMDY
                     AGNMKNNITDLHRRLHQGSYRAQPGRRHYIPKADGKQRPLGIASLEDKIVQYALVKILN
                     AVYENDFMGFSYGFRPGRSQHDALDALATGLVRTNVNWVLDADISQFFDRVSHEWLIRF
                     TEHRIGDRRVIRLIRKWLTAGTSEEGQWRATEEGTPQGAVISPLLANIYLHYVFDLWAH
                     QWRRRYATGNVVMVRYADDIVIGFDKRYDARRFRIAMQRRLREFGLTVHPEKTRLMEFG
                     RFAAENRAIRGKGKPETFNFLGFTHISGKDRNGRFMLIRKTRRDRMTATLKAIKDGLRR
                     RWHYSIPEQGKWLRRVVQGYLNYHSVPGNFPTMQKFRTHVTNLWRRALRRRSQKDDTTW
                     TKANKLAAAWLPRVRVLHPWPVERFTARHPRQEPGA"
                     /name="ltrA"
     gene            2101..3786
                     /locus_tag="C6L86_29955"
     CDS             2101..3786
                     /locus_tag="C6L86_29955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cloacin"
                     /protein_id="QBQ33802.1"
                     /translation="MSGGDGRGPGNSGLGHNGGQASGNVNGTSGKGGPSSGGGTDPNSG
                     PGWGTTHTPNGDIHNYNPGEFGNGGSKPGGNGGNSGNHSGSSGGGQSSATAMAFGLPAL
                     ATPGAEGLALSVSGDALSAAVADVLAALKGPFKFGLWGIAIYGVLPSEIAKDDPKMMSK
                     IMTSLPADAVTETPASTLPLDQATVRVRQRVVDVVKDERQHIAVVAGRPMSVPVVDAKP
                     TKRPGVFSVSIPGLPSLQVSVPKGVPTAKAPPKGIVAEKGDSRPAGFTAGGNSREAVIR
                     FPKETGQKPVYVSVTDVLTPAQVKQRQEEEKRRQQAWDAAHPEEGLKRDYDKAKAELDA
                     EDKNIATLNSRIASTEKALPGARAAVQEADKKVKEAEANKDDFVTYNPPHEYGSGWQDQ
                     VRYLDKDIQNQNEKLKAAQASLNAMNESLSRDKAALTGAMESRKQKEKKAKDAENKLNE
                     EKNKPRKGTKDYGHDYHPVPKTEDIKGLGELKRGDPKTPKQGGGGKRARWYGDKKRKIY
                     EWDSQHGELEGYRASDGEHLGAFDPKTGKQVKGPDPKRNIKKYL"
                     /name="cloacin"
     gene            3796..4053
                     /locus_tag="C6L86_29960"
     CDS             3796..4053
                     /locus_tag="C6L86_29960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cloacin"
                     /protein_id="QBQ33803.1"
                     /translation="MGLKLRLTWFDKKTEEFKGEEYSKDFGDDGSVIESLGMPLKDNIN
                     NGEFDLKKEWVPLLQPFFKNQIKPDVDNCYIAFDYRDGNW"
                     /name="cloacin"
     gene            4138..4287
                     /locus_tag="C6L86_29965"
     CDS             4138..4287
                     /locus_tag="C6L86_29965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010891188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysis protein"
                     /protein_id="QBQ33804.1"
                     /translation="MKKVKTIFLFILIVAGFLLAACQANYIRDVQGGTVAPSSSSELTG
                     IAVQ"
                     /name="lysis protein"
     gene            5438..5743
                     /locus_tag="C6L86_29970"
     CDS             5438..5743
                     /locus_tag="C6L86_29970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QBQ33805.1"
                     /translation="MLDAPDEAAKLLLILRVVSRSLWRTLTGAGTPEKTALGCRLFLSH
                     AGACSLFLRGCAFSAWGGKRLASAVKAERNHHGRDRRRHALGHVRGLCSGGCASRR"
                     /name="hypothetical protein"
     gene            5771..7735
                     /locus_tag="C6L86_29975"
     CDS             5771..7735
                     /locus_tag="C6L86_29975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008321411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mobilization protein A"
                     /protein_id="QBQ33806.1"
                     /translation="MFNTDSLAWQWHIPELARQIYPWVSWLYREYYSLAGFFLVIGLFF
                     GLAELWAGRMRFVGLSHKARREYADRYKRDNNRTVPFSVLASLDSPGRMVRARRHVWNY
                     AYWLTGAAGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLV
                     AGVLLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNA
                     LADFSTEQARKQQAVFLGKDEQGQPVLVPRDTWRKTNIQILGLPGSGKSAMATNALIRC
                     VRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLV
                     AGFNLSETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLIT
                     KLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARD
                     EFRRWPHASIMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPADFV
                     KTTVLDNTPIRWFYRAASQESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQK
                     EARPLFDVNTLQHLPDGFAVMTGLGVARLAFSSPLRVERREISLKTFPVLAKTDPLAEY
                     LPPADGGGPKADDDFAGLY"
                     /name="Mobilization protein A"
     gene            7735..8466
                     /locus_tag="C6L86_29980"
     CDS             7735..8466
                     /locus_tag="C6L86_29980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QBQ33807.1"
                     /translation="MTLEQYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRAKYPVDGRQVSVWGLTPHGVAFSFDEDEPLTDVIPFQP
                     SRVSAAQLPHRLAVQSLRLSMEGRGATGWRYLHRMALKGMKVPDALAELDGRTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRRANGIDEIWYICPDRPTLVRVQRAILAVDEIVNPQTGEA
                     RKTVELDRERLFACFKFMTTE"
                     /name="hypothetical protein"
     gene            8473..9003
                     /locus_tag="C6L86_29985"
     CDS             8473..9003
                     /locus_tag="C6L86_29985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008321413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QBQ33808.1"
                     /translation="MALYMVFIEDVEDKDGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGENPQWERDKPTGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQINAMIEVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
                     /name="hypothetical protein"
     gene            complement(9030..9209)
                     /locus_tag="C6L86_29990"
     CDS             complement(9030..9209)
                     /locus_tag="C6L86_29990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="QBQ33809.1"
                     /translation="MTKQEKTALNMAKFIKDQSLLLLEKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            complement(9235..9663)
                     /locus_tag="C6L86_29995"
     CDS             complement(9235..9663)
                     /locus_tag="C6L86_29995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QBQ33810.1"
                     /translation="MAKTLLNLSQAAQAAGITRRTLYNHVKQGKVTVSRDGKNNPVVDV
                     SELIRVYGNVNIPEKQIPGISHRENTQKNFPQEQLLAMQKELADLRQAVTLMLEDKTSR
                     EEERRQHDDERRKLQAEVDRLTTELTQKKKRFWSGWFS"
                     /name="hypothetical protein"
     gene            complement(9827..10141)
                     /locus_tag="C6L86_30000"
     CDS             complement(9827..10141)
                     /locus_tag="C6L86_30000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="QBQ33811.1"
                     /translation="MPQVTISALAQRDLQRLQDFLKTKNRLAARKGGEVIVRAIQQLKT
                     LPDIGRPVPFLPLEYKELVIGFGDSGYVMLYRHDREMDQIVIVTVRHQKESGYPGADSL
                     "
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(10129..10407)
                     /locus_tag="C6L86_30005"
     CDS             complement(10129..10407)
                     /locus_tag="C6L86_30005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019952150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="QBQ33812.1"
                     /translation="MSSATSIRLDEELKDRLKTLADDRHRSAHALMLEAITEYIDREEK
                     RSQYLRDGQAAWQHYQETGLHLTAEEAEAWISTWGTENEQDAPPCHR"
                     /name="ribbon-helix-helix protein, CopG family"
     gene            complement(10582..10947)
                     /locus_tag="C6L86_30010"
     CDS             complement(10582..10947)
                     /locus_tag="C6L86_30010"
                     /inference="COORDINATES: protein motif:HMM:TIGR01352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB family protein"
                     /protein_id="QBQ33813.1"
                     /translation="MKAFTLTVLAAMFLTPVHAIPLKPVTTLQPTYPVQAAAKRIEGQV
                     TATFDILDDGRVDNVSLTGCHLFFRETLTAMRHWLYPAGHPAMRQVINFEFSLKNDGLQ
                     DPRPVTTQKLNDDGCRQ"
                     /name="TonB family protein"
     gene            complement(10944..11315)
                     /gene="tolA"
                     /locus_tag="C6L86_30015"
     CDS             complement(10944..11315)
                     /gene="tolA"
                     /locus_tag="C6L86_30015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope integrity protein TolA"
                     /protein_id="QBQ33814.1"
                     /translation="MRLIPFILLALCSPLLLTACKHSTTQPPKIYTLDKSSKISSYAAA
                     IKTAVEMQMFEPEAYAGKMCTVRISIQRDGTLNSAIAEGGDPKLCKAAISAVTHAKIPP
                     APDENTWQIFKNAPLDFRP"
                     /name="tolA"
     gene            complement(11589..11834)
                     /locus_tag="C6L86_30020"
     CDS             complement(11589..11834)
                     /locus_tag="C6L86_30020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QBQ33815.1"
                     /translation="MTHLKLTPAEEKRLADAFVAQALAMGLKGNKTLPKAVKQQVRERV
                     LRAIQDEREARRAQEMRREKYEATETTFTWQPQRRR"
                     /name="hypothetical protein"
     BGC             1..8786
                     /name="RiPP-like"
                     /gene="RiPP-like"
                     /tool="antismash"
     Typing          complement(4391..4969)
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="98.282"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          7736..8463
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="93.416"
                     /coverage="100.0"
                     /evalue="1.35e-140"
ORIGIN
        1 atgagaaatt ttcgggaaaa gacgcgatct gcttacaggt ggctccgggc gcttttttgt
       61 gcctgaagat gagaactaat ctcatatatt gacacctgaa aacgggagga gtaaggtaat
      121 aattatactg tgtatatgta cagtgtgcgc cgggagaccg gttagagatc aaggggtgaa
      181 agtccccgac cattgaagga ccagcaatcc acaaggtccc cgagtcatgc gttgcatacc
      241 gcgaggtatg gggcgaagcg ttgacagggg tgttgacagg ccagccattg agccacgaaa
      301 tgtatattaa attaccgggt gccgacgttg tactgttaac ggaaggcaac atcatagggt
      361 gcgatactgc gagtgccaca tggacccggc ggggtctgag accctggcat gtcaatacga
      421 tctctacgcg ggaaccggga gatctcccct ctgaccatct gccagtgtcg gagatggccc
      481 gcaccgggaa gacgaggagt catagccggt gatgtacgga gaggagaagt cggactcgct
      541 catagtagcg gcgaagcagg cgaacaaccc gaaaggagcg gagtcagtgg agcgaaggag
      601 cggggccaag gggaacgcgg aacagccaca catgcgccgg acacagagcc gggaaagcat
      661 gtcacagagg ctgtcacgcg tgcgggaagc tgcgaagcag cggaagaaag aacggtttac
      721 agcattgttc cacctgctga cagtcgaagc actggaagcc gcattcctct ccctgagcag
      781 gaaagcggcc gccggagtgg atggcatcag gtggatggac tacgccggaa acatgaagaa
      841 caacataaca gatctgcacc ggaggctaca tcagggcagc tacagggcgc agcccggcag
      901 gcgtcactac atcccaaaag cggatggaaa acaacgcccg ctcggcatcg cctcgctgga
      961 ggacaagatc gtccagtatg cgctggtgaa aatcctgaac gcagtctatg aaaacgactt
     1021 tatggggttc tcatacgggt tcagacccgg gcgaagccag cacgatgcac tggacgcact
     1081 ggccacaggg ctggtacgca ctaacgtaaa ctgggtactg gatgccgaca tcagtcagtt
     1141 cttcgacagg gtgagccacg aatggctgat caggttcaca gagcatcgga tcggcgaccg
     1201 gagggtaatc aggctcatac gtaagtggct cacagccggg acgtcggagg agggtcaatg
     1261 gcgagcaacg gaggaaggca ccccacaggg tgcggtcatc tcaccgctgc tggcaaacat
     1321 atacctccac tacgtcttcg atctgtgggc gcatcagtgg cgacgtcgct atgccacagg
     1381 caatgtggta atggtcagat acgccgatga catcgtcatc gggttcgaca aacgatacga
     1441 tgcccggcgc ttccgtatag ccatgcagcg cagactgagg gagttcggac tcacggttca
     1501 cccggagaaa acccgtctga tggagttcgg ccgcttcgct gccgaaaacc gtgccatcag
     1561 gggaaaaggc aaaccagaaa cgttcaactt cctcgggttc acgcacatca gcgggaaaga
     1621 tcgcaacggc aggttcatgc tgatacgaaa gacccgccgg gatcggatga cggcaactct
     1681 gaaagccatc aaagacggtc tgcgaaggcg ctggcattac tcaatccccg aacagggaaa
     1741 atggctcagg agagtggttc agggatacct gaactatcac tcggtaccgg gcaacttccc
     1801 caccatgcag aagttcagga cacacgtaac aaacctctgg cgccgggcgc tcaggcgcag
     1861 gagccagaag gatgatacga cctggacgaa agcaaacaaa ctggcagccg catggctacc
     1921 aagggttcgg gttcttcatc catggcctgt ggagcggttc accgccagac acccgaggca
     1981 ggagcccggt gcgtaaatcg cgcacgccgg gatctgtgcg gggggtatcc ggtaacgggt
     2041 atccctaccg cgacatgttg gctttaattt attgttttaa atgtcaaaga ggaaaacggt
     2101 atgagtggtg gagacggtcg aggtccgggt aattcaggtc tgggacataa tggtggtcag
     2161 gccagtggga atgtgaacgg tacgtctggt aaaggtggcc cttcatcagg tggtggtacg
     2221 gatccaaaca gcgggccggg ctggggtacg acgcatacgc cgaatggaga tattcataac
     2281 tataatccgg gggagtttgg taacggcggg agtaaacccg gtggtaatgg tggtaacagc
     2341 ggcaatcata gcggtagctc tggtggcgga cagtcttcgg ccactgcgat ggccttcggt
     2401 ctgcctgccc tggctactcc gggggctgaa ggactggctt tatcagtttc cggcgatgcg
     2461 ttgtcggccg ccgttgctga tgtgctggct gccctgaagg ggccgtttaa gtttggtctg
     2521 tgggggattg cgatctacgg tgtgctgcct tctgagattg caaaagatga tccgaaaatg
     2581 atgtcaaaaa ttatgacgtc attaccggcc gatgcggtga cggagactcc ggcaagtact
     2641 ttaccactgg accaggcgac ggttcgtgtc agacaacggg ttgtggatgt ggtgaaggat
     2701 gagcggcagc atattgcggt tgtcgcaggt cggccaatga gtgtccctgt ggtggatgcg
     2761 aaaccgacaa aacgtccggg ggtattcagt gtgtcgattc cgggtctccc gtctctgcag
     2821 gtgagcgtac cgaaaggtgt tccgacagcg aaagccccgc caaaaggcat tgttgctgaa
     2881 aaaggtgatt cacgtccggc tggttttaca gccggtggta actcccgtga ggccgttatt
     2941 cgtttcccga aagagaccgg acagaagccg gtttatgtgt cggtgacaga tgttcttacc
     3001 ccggcacagg taaaacagcg tcaggaggaa gaaaagcgtc gccagcaggc atgggacgcc
     3061 gctcatccgg aagaggggct gaaaagagac tatgataaag cgaaagctga gctggatgcc
     3121 gaagataaaa atattgcgac cttaaacagc cgcattgcat cgacagagaa ggcgctcccc
     3181 ggtgcaaggg ctgctgttca ggaagccgat aaaaaggtaa aagaggcaga ggcaaataaa
     3241 gatgattttg tgacttataa cccgcctcat gaatatggct ccgggtggca ggatcaggtt
     3301 cgctatcttg ataaggatat tcagaatcag aatgagaaat taaaagcggc tcaggcatct
     3361 ttaaacgcaa tgaatgaatc cttatccaga gataaggctg cacttaccgg ggcgatggag
     3421 agccggaaac aaaaggagaa aaaagcgaag gatgcagaaa ataagttaaa tgaggaaaag
     3481 aacaagcctc gcaaggggac taaagactac ggccatgatt atcatccagt acctaaaaca
     3541 gaagacataa agggacttgg agagttaaag cgaggtgatc ctaaaacacc taaacaaggt
     3601 ggtggtggta agcgggcccg atggtatggc gataaaaaac gtaaaattta tgaatgggat
     3661 tcccagcacg gtgagcttga agggtatcgt gccagtgatg gcgaacacct aggcgcattt
     3721 gatcccaaaa cgggtaagca ggttaaaggg ccagatccaa aacggaacat taaaaaatat
     3781 ctttgagagg taaatatggg gcttaaatta cgtttgacat ggtttgataa gaaaactgaa
     3841 gagtttaaag gggaagagta ttctaaagac tttggtgacg atggttctgt cattgaaagc
     3901 ttgggaatgc ctttaaagga taatattaat aatggtgagt ttgatttgaa gaaagaatgg
     3961 gttcctttac tacagccatt ttttaaaaat caaataaaac ctgatgtgga taattgttat
     4021 atagcttttg attatcggga cggtaactgg taacaaaaaa ttatcaagga tgatttgaaa
     4081 tactgacttc cggtgttcag ggatgaatgc cggagtcttt aaatacaggg aaagtatatg
     4141 aaaaaggtaa agactatttt tctttttata ttgattgttg ctggctttct tctggccgca
     4201 tgtcaggcaa attatatccg ggatgttcag ggcggaacgg tggcaccatc gtcctcctct
     4261 gaactgacgg ggatcgcggt tcagtagaaa agatcaaagg atcttcttga gatccttttt
     4321 ttctgcgcgt aatcttttgc cctgtaaacg aaaaaaccac ctggggaggt ggtttgatcg
     4381 aaggttaagt cagttgggga actgcttaac cgtggtaact ggctttcgca gagcacagca
     4441 accaaatctg tccttccagt gtagccggac tttggcgcac acttcaagag caaccgcgtg
     4501 tttagctaaa caaatcctct gcgaactccc agttaccaat ggctgctgcc agtggcgttt
     4561 tgcgtgcttt cccgggttgg actcaagtga acagttaccg gataaggcgc agcagtcggg
     4621 ctgaacgggg agttcttgct tacagcccag cttggagcga acgacctaca ccgagccgag
     4681 ataccagtgt gtgagctatg agaaagcgcc acacttcccg caagggagaa cggcggacag
     4741 gtatccggta aacggcaggg tcggaacagg agagcgcaag agggagcgac ctaccggaaa
     4801 cggtggggat ctttaagtcc tgtcgggttt cgcccgtact gtcagattca tggttgagcc
     4861 tcacggctcc cacagatgca ccgaaaaagc gtctgtttat gtgaactctg gcaggagggc
     4921 ggagcctatg gaaaaacgcc accggcgcgg ccctgccgtt ttgcctcaca tgttagtccc
     4981 ctgcttatcc acggaatctg tgggtaactt tgtatgtgtc cgcagcgccc gccgcagtct
     5041 cacgcccgga gcgtagcgac cgagtgagcg aggaggcgca atttccccgg cacctgcaag
     5101 acggtcaccg gacgcgctga tgtgggatat tgtcccctga ttaagtcttt ctattccctg
     5161 acgatcaatt atcaggatag gtgaaccatg tcggtttttc gctgaacatt ttacgttaac
     5221 ctatctctgt tgcttttttc tccttgcgga gaaatgcaag tcatccccgc tggggcgtgg
     5281 ctgacttcag gggaaaagac cttgcttacg ctggctggac gccaccgacg cacggtcttt
     5341 tcccctcttt ctggctctgt ccggctggac gccggccacg ccagaaattc acccggcccc
     5401 cgtcaggctc acgcctgacc acccacaaaa atccacggtg ctggacgcac ctgacgaagc
     5461 agcaaagctg ctcctgattt tgcgggtggt cagccgctcg ctatggcgaa ctctgacggg
     5521 ggccggaaca ccggaaaaga ccgcactggg gtgccgcctt ttcctctcac acgctggggc
     5581 gtgctcgttg ttcctccggg gctgcgcctt ttccgcatgg ggcggaaaga ggctggcctc
     5641 cgcggtgaaa gctgaacgca atcaccacgg acgtgaccgc cgccgccatg ccttggggca
     5701 tgtccgcggc ttgtgcagcg ggggctgcgc atcacgccgg taaacccgtc gtctgaagga
     5761 gagagattgc atgtttaata cggattcgct tgcctggcag tggcatatcc cggagctggc
     5821 ccggcagatt tacccgtggg tcagctggct gtaccgggag tattacagtc tggccggttt
     5881 ttttctggtt atcggcctgt ttttcggtct ggctgaactc tgggccggcc gaatgcgttt
     5941 tgtggggctg agccataagg cgcggcggga gtatgccgat cgctataagc gcgataataa
     6001 ccggactgtg ccattttcgg tgctggcctc gctggattca cccgggcgga tggtcagggc
     6061 acggcgacat gtctggaact acgcgtactg gctgaccggc gctgccggtc tggcccttct
     6121 gggggggctg gttgtcgccg tgtttatcga gagctgggga gaaaccgtcc tgcgcccgga
     6181 cctctatgcg aacgcagatt attacctgct gcagccggct aacctgttcg ggatagcctg
     6241 gtgtgccgga gggcttgtcg ccggcgtcct tctggcgcgg ctgctggcgt tcctgctgct
     6301 tgatggtcat tttgcggccg ctgacgaggc ggtgaacgcg aaactgaatc aggagagccg
     6361 gcgcagcagc cagcggaccg gagaaatgac agacgtccgc cacctgcatt tcggggagcc
     6421 ggtaccggtt aacgcgctgg ccgatttttc cacggagcag gcccggaaac agcaggcggt
     6481 gtttctgggt aaggatgagc agggccagcc ggtgctggtc cctcgtgata cctggcgcaa
     6541 gaccaatatt cagatcctcg gcctgcccgg gagcggcaag agcgcgatgg ccaccaacgc
     6601 gctcattcgc tgcgtacgcg atttcgggga cgctgtggtg tacttcgacc ccaaagggga
     6661 cgcgtgggcg ccgcacgtct tccgggcgca ctgcccggac ttcaccctgc tggatctgcg
     6721 gccggggaaa ccggcgcagc tgaatctgtt ccgcgatctc gaccagtacg ccctgaagaa
     6781 tctgctggtt gccgggttta acctgagtga gaccggcgac gtggcggacc actaccgcat
     6841 cagcgagcag aaagcggcga agctgattgc ggagcagttc ccgcaggggg caaacattca
     6901 gcaggtgctg gcggcggcgt acgcgttgcc ggaggccctg aaaaaggacg tgaaggggct
     6961 gatcaccaag ctggagaacg tggccgacct gagcgtcctg cagacggaca gcggtatcga
     7021 tgtggcgggg ataatcaacg gcggcggctg cctgtacgtc atcggctcga tggacgatga
     7081 ggcggtgatc cgggtgcaga agatgctgtt tgcccgctgc gcgcaaatca tcattgcgcg
     7141 ggatgagttc cggaggtggc cgcacgcgag catcatgctc gatgagatta aatatctgct
     7201 gtcgaagtac gtgctgaacg cgctggggac gctgcgcagc cgggactgca acctgctgct
     7261 cgcgcaccag tcgctgggcg acttcggtca gtgcgggcag gatctgcccg ctgattttgt
     7321 gaaaaccacg gtactggata acacgccgat ccgctggttc tatcgcgcgg ccagccagga
     7381 gtccgcgcag tgggcggcgg gccagaccgg ggagatccgg gtggacgtgg agcgccgccg
     7441 ggccagccgg gaggcgggga acgtggagca catcagcggc gacagcttca tccagaagga
     7501 ggcgcggccg ctgtttgacg tgaacaccct gcaacacctg cctgacgggt tcgcggtgat
     7561 gaccgggctg ggcgtggcgc ggctggcgtt cagcagcccg ctgcgggttg agcgccggga
     7621 aatttcgctg aaaaccttcc cggtgctggc gaaaacggac ccgctggcgg agtacctgcc
     7681 tccggccgac ggcggcggac caaaagcgga tgatgatttt gcggggcttt actgatgaca
     7741 ctggagcagt acaacgtcag ccacgcgaag cggcaggcgc ggaacgcgga gaaaacacgg
     7801 ctgaccctgc gctggctgcg ggaagagctg tgttccacgg cggagctggt tgcgcgacgg
     7861 ctggggattg cggcggtaca gccggtttac cgcttcctgg acagtctggt ggcgaaaggg
     7921 ctgctggtcc gggcgaaata cccggttgac ggccgtcagg tcagcgtgtg ggggctgacg
     7981 ccgcacgggg tggcgttctc gttcgacgag gacgagccgc tgacggacgt tattccgttt
     8041 cagccgtcaa gggtgtcggc ggcgcagctg ccgcaccggc tggccgtgca gtccctgcgc
     8101 ctctccatgg agggccgggg ggccaccggc tggcggtacc tgcaccgtat ggccctgaaa
     8161 gggatgaaag tgccggacgc gctggcggag ctggacggca gaacggtggc atttgaggta
     8221 gagcgcaccg tcaagagccg caggcggtat caggaagtgg tgtccgggta tctgttcaac
     8281 cgccgggcga acggcatcga tgaaatctgg tacatctgcc ctgaccggcc gacgcttgtc
     8341 cgggtacagc gggcgattct ggcggtggat gaaatcgtga atccacagac cggcgaggcc
     8401 cgcaaaacgg tggagctgga ccgggagagg ctgttcgcgt gctttaaatt tatgacaacg
     8461 gagtgaggga ttatggcgct gtacatggta tttattgagg acgtggaaga caaagacggc
     8521 gagcgctgca ttatgccaac cagcgagcat ctggaagaca tggtggtgct cgcctggcag
     8581 accggggcgt atgttttctg ttttgtcgac cgggcccagc atctggcgat gatgaaatcc
     8641 atcgggatgt atgacgagcg gctcaacagc gacgaaaaag ccacgtactt tttcaccggt
     8701 gaaaatccgc aatgggaacg ggacaaaccc acaggaatga agctgtgtga ttacctctat
     8761 cgaaaggtgg agcggttcgc catcgagaac ggtgtgcagg tggttgatgc cgggaagtgc
     8821 tcaccggagc agattaacgc gatgattgag gtggtcagcg agcggcacgg ggaaagcgcg
     8881 gtgaacgaga agctgaaagc ggagctgatg cgggaatata acagccgcta ttttaacgtg
     8941 ccggtgcctg aactgccgga ggacaaaccc gcccgccggt ggtggccgtt cggcaaaaaa
     9001 taacgccagc accggcatgg ccggtgctgt tattcttccc cgagcttatc ccgcatcacc
     9061 tgccagagtg tttccgcatc ctcgtgaagc cgttcgcaca tgtcggccgg ggtatccatg
     9121 tccagctcgt tcagcttttc cagcaacagc agcgactgat ccttaatgaa tttagccata
     9181 ttgagggcag ttttttcctg cttcgtcatg ttctccattc ccttcggtaa gttctcagct
     9241 aaaccagccg gaccagaagc gttttttctt ctgtgtcagt tctgttgtca atctgtccac
     9301 ttcggcctgg agtttccggc gctcatcatc gtgctggcgg cgttcttctt cccgggatgt
     9361 tttatcttcc agcatcaggg tgacagcctg ccggagatcg gccagttcct tttgcattgc
     9421 cagaagctgt tcctgtggga aatttttttg tgtattttca cggtgtgaaa tgccgggaat
     9481 ttgtttctca gggatattca catttccgta tacacggatc agttctgaca catccacgac
     9541 agggttgttt ttcccgtcac gtgacacggt aacctttccc tgttttacat gattgtatag
     9601 cgttcttctg gtaatgcccg cggcttgtgc tgcctgtgaa aggttgagca atgttttcgc
     9661 cactgtatac ccctgatttt atcgggtgtg aaaggtgtgt aatttctcac ggtaaatgta
     9721 tcgctgaatt ttacccgttt ttccgttcag gatgtggttt tctgacgcgc tgcgcttgtc
     9781 aaaccggcga cggccacgca atgaattgcg cccccgtcat cggttattag aggctgtctg
     9841 cccccggata cccggattct ttctgatgcc tgacggtgac gatcacaatc tggtccattt
     9901 cccggtcgtg gcggtagagc atcacatagc cactgtcgcc aaacccgatc accagttcct
     9961 tatattccag cggcagaaac ggcaccgggc ggccaatgtc tggcaatgtt ttcagttgct
    10021 ggatagcccg gacgatcacc tcacctcctt ttctggctgc cagccgattt ttggttttga
    10081 gaaagtcctg aaggcgttgt aaatcgcgct gtgccagcgc ggaaatcgtt acctgtggca
    10141 tggcggagca tcctgctcgt tctcagttcc ccaggtactt atccaggctt ccgcttcttc
    10201 cgcagtaagg tgcagacccg tttcctgata gtgctgccat gcggcctgtc cgtcccgcag
    10261 gtactggctg cgcttctctt cccggtcgat gtattcggtg attgcctcca gcattagcgc
    10321 gtgcgctgag cggtgccggt catcggccag cgttttcagc cggtccttaa gttcttcatc
    10381 gagcctgatg gatgttgctg atgacataaa agcccctttg tagtcatatg tattacacat
    10441 gactacttta atccgtggcg gcgctatttg ccagaaatac ggcttttgct gcccattttt
    10501 cagcttcgct tccactaatc agggctgcta caggctcact catcatccag gactattgca
    10561 gcctgcgggt taaaggacct gttactggcg gcaaccatca tcattgagct tttgggtggt
    10621 gactggtcgc ggatcctgta agccgtcatt tttcagactg aattcaaaat ttataacctg
    10681 tcgcattgcc gggtgccctg cgggatatag ccagtgcctc attgccgtca gcgtttcccg
    10741 aaaaaaaagg tgacagccgg taagcgacac gttgtccact cgtccatcgt ccagaatatc
    10801 aaacgtggcg gtcacctgac cttcgatgcg ttttgctgcg gcctgtaccg ggtaggttgg
    10861 ctgcagtgtg gttacgggtt ttagtggtat cgcatgtacc ggagtgagga acatggccgc
    10921 cagcactgtc agagtaaaag ctttcatggt ctgaaatcca gaggggcgtt tttgaatatt
    10981 tgccaggtat tttcatccgg tgccggcgga attttggcgt gggtaacggc tgatattgct
    11041 gctttacaga gtttcggatc tcctccttca gcaatggcgc tgttcagagt gccatcacgt
    11101 tgtatggata tccgcacggt gcacattttt cccgcatagg cctctggttc aaacatctgc
    11161 atttcaacag cggtcttgat ggccgcagcg tagctactga ttttagatga cttatccaga
    11221 gtataaattt tcggcggctg ggtggtggaa tgcttacagg ccgtcaggag taaggggctg
    11281 cacaatgcca gcaggataaa gggtattaaa cgcatcgggt tgatgacctg tcagtaaaaa
    11341 atgttacatg tatatttgtc actctttacg gccacgttca tttacataaa cacggcttat
    11401 cgtatcgttt ttacaccaaa cggcccgcca tgcagttgcg tgcataggca tgcagcgggt
    11461 tacaatttac cgggcgcgtt tccggcggtt ttccgggtgg tttgttgcct gttttatccc
    11521 gtagccgccg gaaacgccct cagaccgtct gagcggtgcg ggcaatgcga cgttatggta
    11581 aatacccctt accggcggcg ctgtggctgc caggtgaagg tggtttccgt agcctcgtat
    11641 ttctcccgac gcatttcctg cgcccgcctg gcttcacgtt cgtcctgaat ggcacgaagc
    11701 accctttccc gcacctgttg ttttaccgcc tttggcagcg ttttgttccc tttcaggccc
    11761 atggccagtg cctgagcgac aaaggcgtcc gccaggcgct tttcttcagc gggagtcagt
    11821 ttcaggtgcg tcatagtggc ctccgggcgt ctcaggtttc ccgaacagtt taaccgcagg
    11881 tcctctcctc atgccagtta gctttcagat gtgtctatac catctgaaat gtaagtgtga
    11941 tgaatgtctt aaataataaa atttgttgcc
//
