LOCUS       CP035933               11195 bp    DNA     circular BCT 20-FEB-2019
DEFINITION  Acinetobacter baumannii strain VB31459 plasmid unnamed3, complete
            sequence.
ACCESSION   CP035933
VERSION     CP035933.1
DBLINK      BioProject: PRJNA494506
            BioSample: SAMN10170272
KEYWORDS    .
SOURCE      Acinetobacter baumannii
  ORGANISM  Acinetobacter baumannii
            Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales;
            Moraxellaceae; Acinetobacter; Acinetobacter calcoaceticus/baumannii
            complex.
REFERENCE   1  (bases 1 to 11195)
  AUTHORS   Veeraraghavan,B., Vijayakumar,S., Neeravi,A. and Venkatesan,M.
  TITLE     Carbapenem resistant Acinetobacter baumannii_VB31459_hybrid assembly
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 11195)
  AUTHORS   Veeraraghavan,B., Vijayakumar,S. and Neeravi,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-OCT-2018) Clinical Microbiology, Christian Medical
            College, Ida Scudder Road, Vellore 632004, India
REFERENCE   3  (bases 1 to 11195)
  AUTHORS   Veeraraghavan,B., Vijayakumar,S., Neeravi,A. and Venkatesan,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-FEB-2019) Clinical Microbiology, Christian Medical
            College, Ida Scudder Road, Vellore 632004, India
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2019
            Assembly Method :: Canu v. 1.7; Unicycler hybrid v. 0.4.6
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 129.0x
            Sequencing Technology             :: IonTorrent; Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/14/2019 10:08:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 4.7
            Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region
            Genes (total)                     :: 4,063
            CDSs (total)                      :: 3,968
            Genes (coding)                    :: 3,544
            CDSs (with protein)               :: 3,544
            Genes (RNA)                       :: 95
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 424
            CDSs (without protein)            :: 424
            Pseudo Genes (ambiguous residues) :: 0 of 424
            Pseudo Genes (frameshifted)       :: 358 of 424
            Pseudo Genes (incomplete)         :: 60 of 424
            Pseudo Genes (internal stop)      :: 54 of 424
            Pseudo Genes (multiple problems)  :: 46 of 424
            ##Genome-Annotation-Data-END##
            Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..11195
                     /organism="Acinetobacter baumannii"
                     /mol_type="genomic DNA"
                     /strain="VB31459"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:470"
                     /plasmid="unnamed3"
                     /geo_loc_name="India: Vellore"
                     /lat_lon="12.9165 N 79.1325 E"
                     /collection_date="2017"
                     /collected_by="Christian Medical College"
     gene            complement(join(10253..11195,1..1469))
                     /locus_tag="D8O08_020255"
     CDS             complement(join(10253..11195,1..1469))
                     /locus_tag="D8O08_020255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="QBF38542.1"
                     /translation="MLNKSKLFLALITLGASKILLAAEGPVTTLNTIVLTAQSDELGSE
                     LLGKSLNVSNQFIDTSKLKQRSTTLGDALGTELGIHSNQYGGGASTPIIRGQEGKRIKV
                     LQNNADVLDMSNMSPDHAVTVEPSLAKSIEIIRGASTLLYSSNSAAGVVNVIDYKIPTQ
                     MPQDGLEGNTTLRFNTGSNEKLTTAGVTVGLSPHVALRAEGLYRNAGNYKTPHYQSSSY
                     NSLEDLENQNSIYKNLKYLPESWAESRVGTLGLSWIDDNTYLGVSYTHRHDEYGLPAHS
                     HLYEGCGASAIGIDSRISGLKNYLLYYPQLMDEQDINYINPRPDCHQHNHIHETNFSHN
                     APYIDLNTRRYDVRGEFTQPFTGIDKIRTSLSYIDYFHNELEGDKITNFFKNTGKVGRI
                     ELSHQPLGELTGILGLQYLEQDNSALSPVHSQEGHTTYLDNQQLLNRNVTKNFSVFGLE
                     KYNWNDFTFELGARIEKQKVSMDYDIEKIKDSMKPWPNKYNSPYVEKNNKIRAQNLKSI
                     LEAVQPNKETAFSYAGTVHWRFAPNYILSLTGTHQERLPNAQEMYTHGMHLATNSFEIG
                     NRFLRKEKSNNLEISLAYKDDLLDYQISTYYYDFDNYIYLQTLNEVLGTTKVRDQHTLR
                     INHYSQSAANFYGLEGNIGYQFNSVYHGSLFGDYVKGRLTNLPDAVIAYDIWNREPTLA
                     PQKDRYTPRLPPARLGTRLKADFDESLKGEIEYYRVFKQDNISKFEQVTSGYNMLNMTL
                     AYKNKLSHTEYDLFFKANNLLDQKVYAHETFLPYIPQIGRNFSLGLNLNF"
                     /name="TonB-dependent receptor"
     gene            complement(1597..1911)
                     /locus_tag="D8O08_020260"
     CDS             complement(1597..1911)
                     /locus_tag="D8O08_020260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006582675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin-antitoxin system, antitoxin component"
                     /protein_id="QBF38532.1"
                     /translation="MSMVRYSHKELNEKFGEKQDAEIQRLLAKGTVPDDQLDLSDIPEI
                     TDWSNAVRQNQFYRPVKQQTSIRLDADVLAWFKAQGKGYQTRMNEILRDAMLKELKNHQ
                     "
                     /name="toxin-antitoxin system, antitoxin component"
     gene            complement(1898..2185)
                     /locus_tag="D8O08_020265"
     CDS             complement(1898..2185)
                     /locus_tag="D8O08_020265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019383542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BrnT family toxin"
                     /protein_id="QBF38533.1"
                     /translation="MEQYFEWDEAKNRKNQKKHDISFETASLVFEDPLRISIQDRYTNG
                     EERWQTIGRVKGVLMLLVAHTIFDEDDCEIIRIISARQVTKAERNKYEHG"
                     /name="BrnT family toxin"
     gene            complement(2453..2752)
                     /locus_tag="D8O08_020270"
     CDS             complement(2453..2752)
                     /locus_tag="D8O08_020270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QBF38534.1"
                     /translation="MDKKIEEKTKDINEKIQKLDLAIQELIETTDNFFINDKYYGIECA
                     FILDHALNIKMHFFNKYPAFAPPHLRGVENYDRIIHIRENNPEDKLEQISPLKD"
                     /name="hypothetical protein"
     gene            complement(2869..3630)
                     /locus_tag="D8O08_020275"
     CDS             complement(2869..3630)
                     /locus_tag="D8O08_020275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017393773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QBF38543.1"
                     /translation="MEMEKAKKRGRPAQLLQIAELHAFVEFLEQQEQLSDLQSQVLKAL
                     NSVDCNFEGLTQTDQVLVKEALKPYREHLKLKLLFEELNNLPLKTEYEQKFLDLYELFQ
                     KNALDQMELNILKTLATRYLNFKAQKLEYSDLELYLSQLQKKDAGKKRKAENQRKFELG
                     GAVLVAFKKLNIDISNDTPQQITNRIVNTTKFHNEVRKSLIFKDVKTYENEYFKANKLF
                     IQVLEGLHTWQKGGELLSVIEIKKALEKGEE"
                     /name="hypothetical protein"
     gene            3935..5104
                     /locus_tag="D8O08_020280"
     CDS             3935..5104
                     /locus_tag="D8O08_020280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002011489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization protein"
                     /protein_id="QBF38535.1"
                     /translation="MASYHFSVKSKNKGYATGHYLYISRLMQYEGIRKTSNETIEHIEP
                     GRCMPAFVKDPIDFWQAADTYERANAKAYMEYEIALPNEFTSEQRKTLIETFLDKHIVP
                     QQYPHSYAIHNVKSRISGEDQPHCHLMFSLKADDGIERSAEQYFKRYNPQDPAKGGAKK
                     IQLQDGHEDYSTFLIYIRKQWENHLNDALAQHCPTVTYTLDGQDITIKNQVSADSYEKY
                     NEIHSTLYLPEPKLGVGQQNATAEYLAQIQKIREHNQQERELEERQKQLDQQHEYFYSA
                     ENNPFSSLEVMYYLNYLIKNATNKDKLKNDLNEIIKNQGPILKQEAWSIYEMNEKLEDS
                     RRNSTPCFEFEVHSLPEYVLPIQNTPPKRTQSEPVQPKADDYDYGGPGF"
                     /name="plasmid mobilization protein"
     gene            5701..6636
                     /locus_tag="D8O08_020285"
     CDS             5701..6636
                     /locus_tag="D8O08_020285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002011482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="QBF38536.1"
                     /translation="MSELIVKDNALIQASYTLDTVEQRLILLAIAEARETGHGITENSL
                     LEVHASSYINTFNVEKHTAYTVLREASKSLFDRYVTYHDINPKTGKDRSFHCRWVDKIG
                     YESQSGIIFLRFTQDIVPLITRLEENFTKYELQQVSRLSSSYAIRLYELLIQWRSAGKT
                     PLFDLSIFRQQLGVKPHQYKTMSNFKTYVLDFALKQVNELTDITAKYEQHKKGRSISGF
                     SFTFKQKKMSNLPIKNKRDPDTIDIFSKMTDAQRHLFSHKLSELPEMGKYSHGTESYPQ
                     FAVRIAEMLQNPEKFKELYPYLQKVGFKAA"
                     /name="RepB family plasmid replication initiator protein"
     gene            6714..7232
                     /locus_tag="D8O08_020290"
     CDS             6714..7232
                     /locus_tag="D8O08_020290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="QBF38537.1"
                     /translation="MKSLTVLELSKLYNINRQTIYNNIKKGILSKNSDNKIDLAEAIRV
                     FGEPVQKQSVKETVKVDSPTSAEVLLLRQQIDLLKNQLDDAKNRESFYQNQIETMQRLL
                     EAPKTNTTQSDDPGSTQAESTVEEKEDVIAMPPKESEVIENKRIPVPEHIEPEPEKRGF
                     WSRFFKPYG"
                     /name="DNA-binding protein"
     gene            7442..7741
                     /locus_tag="D8O08_020295"
     CDS             7442..7741
                     /locus_tag="D8O08_020295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QBF38538.1"
                     /translation="MDKKIEEKTKDINEKIQKLDLAIQELIETTDNFFINDKYYGIECA
                     FILDHALNIKMHFFNKYPAFAPPHLRGVENYDRIIHIRENNPEDKLEQISPLKD"
                     /name="hypothetical protein"
     gene            8307..8663
                     /locus_tag="D8O08_020300"
     CDS             8307..8663
                     /locus_tag="D8O08_020300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005194067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="QBF38539.1"
                     /translation="MWTVITTDLFNEWLEQQDEATQEKVLAALVVLQQQGPSLGRPLVD
                     TVYDSKFTNMKELRVQHRGKPLRAFFAFDPLRQAIVLCIGDKSNKKRFYTEMLAIADEQ
                     YALHLSTLGDQSNG"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            8656..8958
                     /locus_tag="D8O08_020305"
     CDS             8656..8958
                     /locus_tag="D8O08_020305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="QBF38540.1"
                     /translation="MAKSLQELLASRSPESQARIQKMADELLLESQLHLIREELEISQK
                     ELAATLGIKQPSLSAIENRGHDLKISTMKKYVEAMGGKLRIDVELPTGKHIGFNV"
                     /name="XRE family transcriptional regulator"
     gene            8951..9160
                     /locus_tag="D8O08_020310"
     CDS             8951..9160
                     /locus_tag="D8O08_020310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018680077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QBF38541.1"
                     /translation="MSNNKPLKNSTKLLVNLDKFIFLVNAADSLEEIEIIRDLCCEYFS
                     HCKRPSYYIDIFDNAYWIKYYEIA"
                     /name="hypothetical protein"
     gene            complement(9486..9863)
                     /locus_tag="D8O08_020315"
     CDS             complement(9486..9863)
                     /locus_tag="D8O08_020315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005406863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septicolysin"
                     /protein_id="QBF38544.1"
                     /translation="MVQDGDQPSEDPNELLKQVFSLIQEFQKLSYAIHETNALTKLNDG
                     RSLLALLTLRDEFVEQHKTLTAAISNTSRESDRYSTREIKWHKVIPVSSLQKQADDISL
                     KLRDLNVLIQSTNWKIDLIEA"
                     /name="septicolysin"
     Typing          5702..6636
                     /name="rep_cluster_1226"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          4014..5101
                     /name="MOBQ"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 gaatctttaa ttttttctat atcataatcc atactaactt tctgcttttc tatacgagca
       61 cctagttcga aagtaaagtc gttccagtta tatttttcta ggccaaatac actaaagttt
      121 ttagtgacat ttcgatttaa tagctgctga ttatctagat aggtggtatg gccttcttga
      181 gaatggactg gtgataaagc actattatcc tgttccaaat attgtagccc caagataccg
      241 gttaattccc ctaatggctg atgtgataac tctatgcggc ctacttttcc tgtattttta
      301 aaaaagttag taatcttatc tccctcgagt tcattgtgaa aataatctat ataactcaat
      361 gaggtacgaa ttttgtcaat accggtaaat ggttgagtga attctccacg cacatcataa
      421 cgtcgagtat ttaaatcaat ataaggagca ttatgagaga aattagtttc atgaatatga
      481 ttatgctgat gacaatcagg acgtggattt atgtaattaa tatcttgctc atccatcaat
      541 tgaggataat ataaaagata attttttaat ccactaattc gtgaatcgat accgattgca
      601 gaggcaccac aaccttcata taaatggcta tgggctggta aaccatattc atcatgacga
      661 tgtgtataag aaactcctaa ataagtatta tcgtctatcc aggataatcc aagcgtacct
      721 actctcgact ctgcccagct ttctggtaaa tattttaaat ttttataaat actgttttgg
      781 ttttcaagat cttctaaaga attataagag ctagactggt aatgaggagt tttatagtta
      841 ccagcattac gatataaccc ttctgcccgt aaagctacat gtgggcttaa gccaactgtt
      901 acacctgctg tggtcaactt ctcattactg ccagtattaa aacgtaatgt agtattaccc
      961 tctaatccgt cttgaggcat ttgggttgga attttatagt caatgacatt gactacccct
     1021 gccgcactat ttgaactata caaaagggta cttgcaccac gtataatttc aatagactta
     1081 gctaaacttg gttcaactgt gacagcgtga tctggagaca tattagacat atccaacacg
     1141 tcagcattat tctgtaaaac tttaatacgt tttccttcct gcccacgaat aataggagta
     1201 gatgctccac ctccatattg attagaatga attcctaatt ccgtacccaa ggcatcccct
     1261 agagttgtcg aacgctgttt aagtttacta gtatcaataa actgattact aacatttaga
     1321 cttttgccta acagctcaga ccctaactca tcagattgtg cagttaatac tattgtattt
     1381 aaggtagtaa caggcccttc agctgccaat aaaattttcg aggcccctaa agtaattaaa
     1441 gctaaaaata gtttactttt atttagcata aaacaaccaa atttaatgtt atattataat
     1501 ataacactta aaaatttata aaatctacta tttaaatttt tgaatggtaa tcccccctaa
     1561 aaatgaagtc aaaaatggga gcctaagctc ccattcttat tgatgatttt ttaattcttt
     1621 tagcatagca tctcgtaaaa tttcattcat acgtgtttga taacctttgc cttgtgcttt
     1681 gaaccaagca agtacatcag catctaaccg aattgaagtt tgttgcttta ctgggcggta
     1741 aaattgattt tggcgtacag cattgctcca gtctgtaatt tcaggaatat ctgatagatc
     1801 tagctgatca tcaggaaccg tgcctttagc aagcaagcgt tgaatttcag catcttgctt
     1861 ctcaccaaat ttctcattca gctctttgtg tgagtatcta accatgctca tatttgtttc
     1921 gctccgcttt agtgacttgc cttgcactaa tgattcggat gatttcacag tcatcttcat
     1981 caaaaatggt gtgagccacc aataacatta gtacgccttt aactcgtcca atggtttgcc
     2041 aacgttcttc accattagta tatctgtctt ggattgagat ccgtaatgga tcttcaaaaa
     2101 caaggcttgc agtttcgaaa gagatatcat gctttttctg attctttcga ttcttagcct
     2161 catcccattc aaaatactgt tccataaaaa atattcaaat ttgtatatac aataatgtat
     2221 cacgaaattg tatcactcaa gttgagaagc gtaattttta gtcagattta ttggcaaaaa
     2281 ctatcaaaat cgatcataaa aaagccgact tgtttcaaag tcggcttttt gggcattttt
     2341 ggatttttat atttttatta agtagttgat atttaaatta atatacaagt gtacttcgta
     2401 taatatccat tatgttaaat agtaggggac tctaagtaca agattagaaa atttagtctt
     2461 taagaggaga aatttgttct agcttatctt caggattatt ttctctaata tgtataattc
     2521 gatcataatt ttctactcct cgtaagtgag gtggtgcaaa tgctggatac ttgttgaaaa
     2581 agtgcatttt aatatttagt gcatggtcta aaataaaagc acattcaatt ccatagtact
     2641 tatcattaat aaaaaaattg tctgtagttt ctattagttc ttgaatagct aaatccaatt
     2701 tttgaatttt ttcattaata tctttagttt tctcttctat ctttttgtcc attggtatca
     2761 cctatagaat taagtttccc taaaattaac ataatacacc ttatgcgaaa ttccaatgta
     2821 agcccaaaat agaaatgtcc aacttctcta aaatccctgc taaataaact actcttcgcc
     2881 tttttctaag gcctttttaa tttcaattac tgacaataat tctccgccct tttgccaggt
     2941 atgtaatcct tctaacacct gaataaaaag tttatttgct ttaaaatatt cattttcata
     3001 tgtcttaaca tctttaaaaa ttaaagattt acgtacttca ttatgaaact ttgtcgtatt
     3061 cacaatccga ttggtaatct gttgaggagt atcattgcta atatcaatat tgagtttctt
     3121 aaatgcgaca agaacagcac cacctaattc aaatttacgt tgattttcag ctttgcgttt
     3181 tttcccagca tccttcttct gtagctgact caaatacaat tctaaatcac tgtattcaag
     3241 cttttgcgct ttaaaattca gataccgtgt cgccaaggtt tttaaaatat ttagttccat
     3301 ctgatctagt gcattctttt gaaaaagttc atacagatct aaaaacttct gttcatactc
     3361 ggttttaaga ggcagattat tcaactcttc aaacagcaat ttcaacttca gatgttcacg
     3421 ataaggtttt aaagcctctt tgaccagaac ctgatctgtc tgagttagcc cctcaaaatt
     3481 acaatcaaca ctatttaaag cctttaacac ttgagattga agatcagaaa gctgttcttg
     3541 ctgttctaaa aactctacaa atgcatgtaa ctcagcaatc tgtaacaact gagcaggtcg
     3601 accacgcttt tttgcttttt ccatttccat catctgccgc caaattttca gaactgcaac
     3661 ctctttaaat atggttttac catatttaaa gagggcagtc tgaaaataat tatttaatat
     3721 aaaaataaaa attcttttca agaaatttta tttttatatt aaataattcg cacttgacag
     3781 tttctcctca tcggagaaac tagtacgcaa tggggcgctt cccccttgac ccccttcaac
     3841 cggatttttc agccatacag gcatttcaaa tccgggcggt tttcattccg tttcactgca
     3901 taaaaaccga acccacaacc cagcagaggt gaacatggcc agctaccact tcagcgtcaa
     3961 aagcaaaaat aagggctatg cgaccggcca ttatctctac atttcccggc tgatgcagta
     4021 tgaaggcatc cgcaaaacca gcaatgagac catagaacat attgaacctg gtcgatgtat
     4081 gcctgccttt gtaaaagatc ccattgattt ttggcaggca gcagatacgt atgaacgagc
     4141 caatgccaag gcctacatgg agtatgaaat tgccctaccg aatgagttca cgtcagaaca
     4201 gcgtaaaacg ctcatagaga cgtttttaga caaacatata gttccacagc aatatccgca
     4261 ctcatacgcc atacacaacg taaaatcacg tatcagtggc gaagatcagc ctcattgtca
     4321 tctgatgttc tcgctaaaag cggatgacgg cattgaacgc agcgcagaac agtacttcaa
     4381 acgctataac cctcaagatc cagccaaagg cggtgccaaa aaaatccaac ttcaagatgg
     4441 ccatgaagac tattccactt ttttgatcta tatccgaaaa caatgggaaa atcatttgaa
     4501 tgatgccctt gcacagcact gcccgaccgt cacctacaca ctggatggcc aagacatcac
     4561 catcaaaaat caggtttcag cagacagcta tgaaaaatat aacgagatcc acagcacgct
     4621 ataccttcca gagccaaaac taggcgttgg acaacaaaat gcgacagcgg aatatctcgc
     4681 ccaaatccaa aaaatcagag aacacaacca gcaagaacga gaactcgaag aacgccaaaa
     4741 gcaattagat caacaacatg aatattttta tagtgctgaa aacaacccat tttcatcatt
     4801 ggaagtcatg tattacctga attacttaat caagaatgca acaaataagg acaaactaaa
     4861 aaatgatttg aatgaaatta tcaaaaacca aggccctata cttaaacaag aagcttggtc
     4921 catctacgaa atgaatgaaa aactagaaga ctcaagacgt aacagtaccc catgttttga
     4981 gttcgaggtg cattcacttc ctgaatacgt attaccgata caaaatacgc ctcccaaacg
     5041 cactcaatca gaaccagtac aacctaaagc tgatgattat gattacggtg gccctggttt
     5101 ttaagctcag ttggttttat ccaaagttta cagagcgagt gtctacgagc gaacagacac
     5161 aattaaaatt tttgccatgc tttttccctg attacaaact cccctttgct gctgagactg
     5221 agatacagag catcccggag ggtgcgaaca gatttaattt gcatctaggt cgagcgaagc
     5281 gagtataaaa aacttatgag cgaagcgaat tccgagttgc ttttgctttt ttgaagttat
     5341 cacgagatta acccaaaaat tgccccttcg aactgagcgt aagcgaagtt caatagagtt
     5401 tgagcgtagc gaaaacatag ggcaattttt cattcattgg gcttttaatt atttttaatc
     5461 ttttaaatgc ttttaaataa gctgtaaacc tttatttata atagtttcat agttaataaa
     5521 actaggttta tcgacccata aaactaggtt tatcgaccca taaaactagg tttatcgacc
     5581 cataaaacta ggtttatcga ccttaaagct aggtttatcg acccataatt aagttaattt
     5641 acaactcaat tgaaatagtc tattgtacaa cctagtttaa ttataaattt attattagaa
     5701 atgagtgaat taatcgtaaa ggataatgct ctaattcaag caagttatac cttagataca
     5761 gttgaacaaa gactgatcct attagccatt gctgaagctc gagaaactgg acatgggata
     5821 actgaaaata gtcttttaga agtacatgca agtagttata taaatacttt taatgtcgag
     5881 aaacataccg cttataccgt actcagagag gcatctaaaa gcttatttga tcgctatgtc
     5941 acataccatg acattaatcc taagacaggt aaggatcgta gctttcattg tcgttgggtc
     6001 gacaaaattg ggtatgaatc tcaatcagga attattttcc tacgattcac ccaagatatc
     6061 gttccactca taactcgact tgaagaaaat ttcactaaat atgaattgca gcaggtttct
     6121 aggttaagta gctcatatgc tattcggcta tacgagctat taattcaatg gagatctgcc
     6181 ggaaaaacgc cactttttga tctatctatc tttagacaac aacttggtgt caaacctcat
     6241 caatacaaaa caatgagtaa ctttaaaaca tatgttttag attttgctct taagcaggta
     6301 aatgagttaa ccgatataac agctaaatat gagcaacata aaaaagggcg ttctatttca
     6361 ggtttttcat tcactttcaa acagaaaaaa atgagtaatc tgccaataaa aaataagcgt
     6421 gacccagaca ctatagatat tttctcaaaa atgacagatg ctcaacgcca tctgttttcc
     6481 cacaaactgt cagaacttcc tgaaatggga aagtattctc atggtacaga aagctatccg
     6541 caattcgctg tacgcattgc agaaatgctt caaaacccag aaaagtttaa agaactctat
     6601 ccttatctcc aaaaagtagg cttcaaagct gcatagaaga tagacttgct gatttgtcta
     6661 ttagacagtc taatagacac taatttttta caagattagg cagagattta cacatgaaaa
     6721 gccttacagt tcttgagctt tctaagcttt acaatattaa tcgacaaacc atttacaaca
     6781 atataaagaa aggtatttta agtaaaaatt ctgacaataa gattgatctt gcagaagcga
     6841 tccgggtatt tggtgagcca gtacaaaaac agagtgtaaa agaaactgta aaagtagaca
     6901 gtccaacttc ggcagaagtt ttactcctta gacagcagat agacctacta aaaaatcagc
     6961 tagatgatgc aaaaaataga gaaagcttct atcaaaatca aattgaaact atgcaacgcc
     7021 tattggaagc tccaaaaacc aatacaacac aatctgatga tcctggatca acacaggcag
     7081 aatccacagt agaagaaaaa gaggacgtca tagctatgcc tcctaaggag tcagaggtta
     7141 tcgagaataa gcgtattcca gtccctgaac atattgagcc agaaccagaa aaaaggggct
     7201 tctggagccg ttttttcaag ccctatggat gataggacta tttaatcaga ctaatcaaaa
     7261 ccgtggaaca atgatcaata attgatcgtg aaacataaaa aatcactaaa acagcctgag
     7321 cgtgactgct taggctgttt ttacatccat aagacattgt tttaaaatgc tttttacaaa
     7381 gaatttcgta taaggtgtat tatgttaatt ttagggaaac ttaattctat aggtgatacc
     7441 aatggacaaa aagatagaag agaaaactaa agatattaat gaaaaaattc aaaaattgga
     7501 tttagctatt caagaactaa tagaaactac agacaatttt tttattaatg ataagtacta
     7561 tggaattgaa tgtgctttta ttttagacca tgcactaaat attaaaatgc actttttcaa
     7621 caagtatcca gcatttgcac cacctcactt acgaggagta gaaaattatg atcgaattat
     7681 acatattaga gaaaataatc ctgaagataa gctagaacaa atttctcctc ttaaagacta
     7741 aattttctaa tcttgtactt agagtcccct actatttaac ataatggata ttatgcgaaa
     7801 tggatcttta agattacttt aagatcagta gcttacattg agtcataccc tctggaacga
     7861 cctcgttcaa ccgacttaga aacaagtcgg tttttttatg ctcaattttg atacttcttg
     7921 ccaataaaat tgtttaaaaa ataatcaaaa atagcaattc catagagttt ataagctttt
     7981 ttacccaaaa gaatccacta tttctgtgga taaccactgg gataaatttt gattattttt
     8041 tgtacgtttt ggcttacagc gtttcacgaa attgtctgta tctatccccc gatgaagctc
     8101 ttatgatcga tctatatgga caggatgttc aatgacttaa aacaacaata ataatcagtc
     8161 aggcaccatg accatcaggt agtcagccct acctatgcgc tccataccga aaaatcccga
     8221 catgacgtcg ggatttttta ttgccatttg caaagtcatt caatcagatt taatatatag
     8281 actgtaatct atattgtgat tgtaatatgt ggacagtcat tacaacggat ctgtttaatg
     8341 aatggcttga acagcaagat gaagcaacac aagagaaagt cttagctgca ttggttgttc
     8401 tacaacagca agggcctagt ttaggtcgtc ctttagtaga taccgtctac gattctaaat
     8461 ttaccaatat gaaggaacta cgtgttcagc atcgtggtaa accgttaagg gcattttttg
     8521 cattcgatcc cctaagacaa gcgattgtgc tgtgtattgg tgataagagt aataaaaagc
     8581 gtttttatac agagatgcta gcaattgcag atgagcaata cgcacttcat ctctcaactt
     8641 taggagatca atctaatggc taagagctta caagaattat tggctagtcg ctctccagag
     8701 agtcaagctc gtattcaaaa aatggctgat gaattacttt tagaaagtca gcttcacctt
     8761 atccgagaag agttagaaat ttcccagaaa gaactagctg caacccttgg aattaaacag
     8821 ccgtcattat cagcaatcga aaatcgtggt catgatctta aaatttcaac gatgaaaaag
     8881 tatgttgaag caatgggtgg aaaacttcgt attgatgtag agcttccaac aggaaaacac
     8941 atagggttca atgtctaata ataaaccttt gaaaaatagt actaaattac ttgttaactt
     9001 agacaagttt atatttttag tcaatgctgc cgatagccta gaagaaattg aaattattag
     9061 agatttatgc tgtgaatatt tttcacattg taagaggcca agctattaca ttgatatttt
     9121 tgacaatgct tattggataa aatattacga aatagcttaa tccttctaga ttcgcataag
     9181 agattttatg ttaaatgccg aaatgaatta aaaatagaaa tgtagttgag ctgatgcttg
     9241 ctcatttctt tatttttagt aattgaggtg aacatactgt cagtacatgg tagttataag
     9301 taacgtgtaa ctttgtttgc acaaagattt gagttatgcc aagtgatgga ttgatttgta
     9361 cttaaaattt taagcttatc cacttgcttt gcaagccact acactttatt tacaatccta
     9421 tgttgtggaa gtaagggatc ttgtactcgc ccagtatgtt caacttgatt atatctaaag
     9481 gactattagg cttcaatcaa atcaattttc caattagtcg actgaattaa cacgtttaaa
     9541 tcacgtaatt taagactaat atcatcagct tgtttttgta atgatgaaac tggaataact
     9601 ttatgccact ttatttcccg cgtactataa cgatcagatt cacgagatgt attacttatt
     9661 gctgcagtta gggttttgtg ctgttctaca aattcatcac gcaaagtcaa taaagcaagt
     9721 agagaacggc catcatttaa ttttgttaaa gcattagttt catgaattgc ataacttaat
     9781 ttttgaaatt cttgaattaa agaaaatact tgttttagta gttcatttgg atcttcagat
     9841 ggttgatcac catcttgtac caatacattt gcattgatac gttgttttag tgaaataatt
     9901 tttttgttga tcacttcgaa gtaagagagc ttctgctaat ttcatttttc acctattaac
     9961 caattagaat taagttttaa acagcttata tcctcattct ttaaagatca aaaaaaaaat
    10021 tgctttttat ctagctaaaa ggtgtctaca aaatcggtgg ctattcagtg ctgaaaaggc
    10081 tgccgacaca taaagtgacc cagattgaag agttactgcc acactgctgg aaacctaaat
    10141 cgaattaaaa aataggtatg ggattcagcg gacgcttacc ttaattatta atctaatcat
    10201 tttataagaa aaatcttcta agaaattttc ttagaagatt acagtatctt atctagaaat
    10261 taagatttaa gcctaaacta aaatttcttc caatttgggg aatatatggc aaaaatgttt
    10321 catgggcata gactttctga tcaagtaaat tattcgcttt aaagaataaa tcatattctg
    10381 tgtgagatag cttattttta tatgctaaag tcatattaag catattataa cctgatgtaa
    10441 cctgctcaaa tttagaaata ttatcttgtt taaagactcg ataatattct atttcacctt
    10501 taagcgattc atcaaaatca gcttttagtc gtgtacccaa acgagcagga ggtaatctag
    10561 gagtgtaacg atccttttgg ggagctaaag tcggttctct attccagata tcgtatgcaa
    10621 ttacagcatc aggtaaattt gttaaacggc ctttcacata atctccaaaa agagagccgt
    10681 gataaacaga attaaattga taccctatgt tgccctctaa tccataaaaa ttagcagcag
    10741 actggctata atgattaata cgtagtgtat gctgatctct aacttttgta gttcctaaaa
    10801 cttcattgag tgtctgtaaa tatatatagt tatcaaaatc ataatagtaa gtactgattt
    10861 gataatcaag taaatcatcc ttataggcca gactgatttc taaattattg gatttctctt
    10921 ttcttagaaa gcggttacct atttcaaaag aattagtagc gagatgcata ccatgagtat
    10981 acatttcttg tgcattaggt aatctttctt gatgtgtacc tgttaatgat aagatataat
    11041 ttggagcaaa tctccagtgg actgtacctg cataagaaaa agctgtttct ttgttaggtt
    11101 gaacagcttc taaaatagat tttaaatttt gagccctgat tttattattt ttttctacat
    11161 aaggactgtt atatttatta ggccaaggtt tcatt
//
