LOCUS       CP035911                9729 bp    DNA     linear   BCT 19-FEB-2019
DEFINITION  Klebsiella pneumoniae strain BA4656 plasmid pColRNAI.
ACCESSION   CP035911
VERSION     CP035911.1
DBLINK      BioProject: PRJNA521675
            BioSample: SAMN10908921
KEYWORDS    .
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 9729)
  AUTHORS   Veeraraghavan,B., Shankar,C., Vasudevan,K., Narasimman,V.,
            Neeravi,A.R. and Venkatesan,M.
  TITLE     Hypervirulent Multidrug resistant Klebsiella pneumoniae
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9729)
  AUTHORS   Veeraraghavan,B., Shankar,C., Vasudevan,K., Narasimman,V.,
            Neeravi,A.R. and Venkatesan,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-FEB-2019) Clinical Microbiology, Christian Medical
            College, Ida Scudder Road, Vellore, Tamil Nadu 632004, India
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2019
            Assembly Method :: Canu v. 1.7; Unicycler hybrid v. 0.4.6
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 58.0x
            Sequencing Technology :: IonTorrent; Oxford Nanopore MiniION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 02/12/2019 14:22:32
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 4.7
            Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region
            Genes (total)                     :: 6,254
            CDSs (total)                      :: 6,129
            Genes (coding)                    :: 5,530
            CDSs (with protein)               :: 5,530
            Genes (RNA)                       :: 125
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 89
            ncRNAs                            :: 11
            Pseudo Genes (total)              :: 599
            CDSs (without protein)            :: 599
            Pseudo Genes (ambiguous residues) :: 0 of 599
            Pseudo Genes (frameshifted)       :: 448 of 599
            Pseudo Genes (incomplete)         :: 160 of 599
            Pseudo Genes (internal stop)      :: 62 of 599
            Pseudo Genes (multiple problems)  :: 64 of 599
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            Bacteria and source DNA available from Department of Clinical
            Microbiology, Christian Medical College, Vellore, India.
            Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..9729
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="BA4656"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="pColRNAI"
                     /geo_loc_name="India"
                     /lat_lon="12.9165 N 79.1325 E"
                     /collection_date="2018"
                     /collected_by="Christian Medical College, Vellore, India"
     gene            complement(<1..126)
                     /locus_tag="EXC92_31180"
     CDS             complement(<1..126)
                     /locus_tag="EXC92_31180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="QBE75939.1"
                     /translation="MTKQEKTALNMAKFIKDQSLLLLEKLNELDMDTPADMCERLH"
                     /name="Rop family plasmid primer RNA-binding protein"
     gene            195..572
                     /locus_tag="EXC92_31185"
     CDS             195..572
                     /locus_tag="EXC92_31185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="entry exclusion protein 1"
                     /protein_id="QBE75940.1"
                     /translation="MAWVTVRQATELTGKARSSLYRDMAKGRVSYRTEADGGRVVDTSE
                     LIRVYGELRQIETHERDGLRLSDETEKMASDALIAEIKALREEVAGLRQEMQAMRLLEH
                     KPETAETPAGTSRRWWQWGKR"
                     /name="entry exclusion protein 1"
     gene            complement(634..933)
                     /locus_tag="EXC92_31190"
     CDS             complement(634..933)
                     /locus_tag="EXC92_31190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009365129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="QBE75941.1"
                     /translation="MPYEVEWKQGAIEDVTALFDYIAENSSLWDAQNVTDRVLAAADKL
                     ADFPRLYEVDSRYGEDVRRISLMGQHVLYDVDDQTRKVRVLAVVGQRQNPHTVR"
                     /name="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(923..1186)
                     /locus_tag="EXC92_31195"
     CDS             complement(923..1186)
                     /locus_tag="EXC92_31195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000072676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein"
                     /protein_id="QBE75942.1"
                     /translation="MSNSTHYENANFLRELAERLPRILPEGGPDKAALLQRLANEELAQ
                     AEYEDQVRAKVTAARADTRPGMTTEQLRQRLHGRYQELRDAV"
                     /name="plasmid stabilization protein"
     gene            1563..2648
                     /locus_tag="EXC92_31200"
     CDS             1563..2648
                     /locus_tag="EXC92_31200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006327147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YncE family protein"
                     /protein_id="QBE75943.1"
                     /translation="MAITIKSAVNVRSRVLIYSLLLFTGSAYAADIAESTFLTRDIGNG
                     LYEMSFDGKNNSLWAASSSSFDRDKGHGIVYQLEPSTLKTKSAVKIARLGFATALDEEH
                     ERLYIGNTLDGSVTVIDTLTGKELSVIPLTEGQDEAHFRPTREMVIDKKNQRLYVSSAA
                     DKGALWVIDMAVGKKIKTIDGLGHAVTGIALNKNGDNIYLVNGDGEIINLDASSYEIKK
                     RFVVEPEKKHFFLNVSLDEKNGRAFITDPDIPGVLVVDVNSGKILHRIDVINSLAILFN
                     PLRNEIYITHRNAKQVSIVDSNSYYVKTTIKTRLMPNSLSLSHDGENLYVSVKQEKKEM
                     STMKDYILKIELSKIAMEPEE"
                     /name="YncE family protein"
     gene            2645..4834
                     /locus_tag="EXC92_31205"
     CDS             2645..4834
                     /locus_tag="EXC92_31205"
                     /inference="COORDINATES: protein motif:HMM:TIGR01783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent siderophore receptor"
                     /protein_id="QBE75944.1"
                     /translation="MNKYLGLSIVYMMYTSSVMADDSGAVSKDKNISPEETLIVHGTAV
                     SESTTEGTDSYTTQSANTASKMNLSFRDTPQSTTVITRRRMDDVAAKNIIDVVKTAPGL
                     YVSTAEGSGRPNFMSRGFNANVMYEGFSLPWNSYIPSSQTSSAIFDRVEIVRGATGLVQ
                     GAGDPSAAINMIHKRPTRQYQASTNIGAGRWNDYRGGVDVSGPLNDSATLRGRAVVDGE
                     NSETFRDSEKRRNNVIYGIMEADLTDNTLLTIGGYQQYEYNNHWWYDLPISGTGHHLNL
                     PRSTFTGNDWEFERSKSKTAFATLEQKFSNSWKLKFSTLQNWRNADLLGTATYRHKDTR
                     QSMYQQVWGSLREYNSKSYDLSLNGDYALFGRVHQFVAGTTQQKYTDKDTGYTYSPIYI
                     ENVNIFDHGSHSSKKPMKMSGDASYDVTEQKSAYAATHFLLSDNWKILLGGRLDWYEYT
                     SKGTSINTGYKVTRNITKYAGSTYNLDDHHTIYGSYTDIFNPQSSTDLNGKVIKPIVGK
                     NYETGIKGEYFNGLLNASLAVFQVDQENRARLLPDQTGCVTNGNPQCYEASGKVRTKGI
                     DFELQGMVTPLWEIGVGYTYADTRYIKDGDRSNEGKRFNTAVSPQNLFKISSMYTFDGK
                     LTNWRAGVNTYWQSKIYANITDTRDGNPVINKQKAYSTTDIIIGYTPMPQLDLQLNITN
                     VFDKVYYTSIGESIGYGTETYGEPRNVKISATYRF"
                     /name="TonB-dependent siderophore receptor"
     gene            complement(5151..5300)
                     /locus_tag="EXC92_31210"
     CDS             complement(5151..5300)
                     /locus_tag="EXC92_31210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016240737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="QBE75948.1"
                     /translation="MGCKQELPVQPDCCALSGNCSLESNPERHAKTPLAAAIGNWEFAE
                     DLFS"
                     /name="replication initiation protein"
     gene            complement(5290..5515)
                     /locus_tag="EXC92_31215"
                     /pseudo=""
     CDS             complement(5290..5515)
                     /locus_tag="EXC92_31215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001373453.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            6087..6391
                     /locus_tag="EXC92_31220"
                     /pseudo=""
     CDS             6087..6391
                     /locus_tag="EXC92_31220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146433.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            6419..8380
                     /locus_tag="EXC92_31225"
     CDS             6419..8380
                     /locus_tag="EXC92_31225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008321411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mobilization protein A"
                     /protein_id="QBE75945.1"
                     /translation="MFNTDSLAWQWHIPELARQIYPWVSWLYREYYGLAGAFLVIGLFF
                     GLAELWAGRMRFVGLSHKERREYADRYKRDNNRTAPFSVLASLDSPGRMVRARRHVWNY
                     AYWLTGAAGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGIVWCAGGLV
                     AGILLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNA
                     LADFSTEQARKQQAVFLGKDEQGQPVLVPRDTWRKTNIQILGLPGSGKSVMGTNALIRC
                     VRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLV
                     AGFNLSETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLIT
                     KLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARD
                     EFRRWPHASIMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPAEFV
                     KTTVLDNTPIRWFYRAASQESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQK
                     EARPLFDVNTLQHLPDGFAVMTGLGVARMAFSSPLRVERREIPLQRFPVLAKTDPLAEY
                     QPEAGRQRPGDDDFAGLY"
                     /name="Mobilization protein A"
     gene            8380..9111
                     /locus_tag="EXC92_31230"
     CDS             8380..9111
                     /locus_tag="EXC92_31230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QBE75946.1"
                     /translation="MALERYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRAKYPVDGRQVSVWGLTPHGVAFSFDEDEPLTDVIPFQP
                     SRVSAAQLPHRLAVQSLRLAMEARGASGWRYLHRMALKGMKVPDALAELDGRTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRKANGIDEIWYICPDRATQVRVQRAILSVDEIVNPQTGEA
                     RKTAELDRERLFACFKFMTTE"
                     /name="hypothetical protein"
     gene            9118..9648
                     /locus_tag="EXC92_31235"
     CDS             9118..9648
                     /locus_tag="EXC92_31235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008321413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QBE75947.1"
                     /translation="MALYMVFIEDAEDRDGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGKNPQWERDKPAGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQISAMIEVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
                     /name="hypothetical protein"
     Typing          complement(5040..5620)
                     /name="ColRNAI_rep_cluster_1857"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="98.625"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          8381..9108
                     /name="MOBC"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="95.885"
                     /coverage="100.0"
                     /evalue="3.84e-144"
ORIGIN
        1 gtgcagccgc tcgcacatgt cggccggggt atccatatcc agctcgttca gtttctcgag
       61 taacagcagc gactggtcct taataaattt agccatattg agggcagttt tttcctgctt
      121 agtcatgttt tctgtccttc cgggtgtggt gtgcttcctg tcgggtatac tgtctcaaaa
      181 ccggaggtga gacaatggcg tgggtgacgg tgagacaggc gacggaactg acggggaaag
      241 cccggagttc cctgtatagg gatatggcga aaggccgcgt atcataccgt actgaagctg
      301 atggtggtcg ggtggtggat accagcgaac ttatccgggt gtacggtgaa ttaagacaga
      361 ttgagactca cgagcgggac gggttgagac tgtcggatga gactgaaaaa atggcctccg
      421 acgcgttgat cgcggagata aaagcactca gggaggaggt ggccggactg cggcaggaaa
      481 tgcaggccat gagactgctg gaacacaaac cagagacagc agagacaccg gccggaacat
      541 cgcgccgatg gtggcagtgg ggaaaacgct gacgcgctgt gcttgtccaa ccggcgacgg
      601 ccacgcaatg aattgcgccc ccatcaccgg ttatcagcga acggtatggg gattctggcg
      661 ctggccaacc acggccagaa cccggacttt cctggtctgg tcatcaacat catagaggac
      721 atgctgtccc atcagactga tccggcgaac gtcctcgcca tagcgtgagt ccacttcata
      781 taggcgcggg aagtcggcca gtttgtccgc tgcagcgaga actcgatcgg taacgttctg
      841 cgcatcccac agggatgaat tttccgcaat gtagtcaaac aatgctgtca catcctcgat
      901 ggctccctgc ttccattcca cctcatacgg catcgcgtag ttcctgatag cggccatgca
      961 gtctctggcg gagttgttcc gtggtcatgc ccgggcgcgt gtcagcgcgg gcggcggtca
     1021 ctttagcgcg aacctgatct tcatattctg cctgggccag ttcttcgtta gccaggcgct
     1081 gcaacagtgc agctttgtcc gggccacctt caggcagtat gcggggcagt ctctcggcca
     1141 gttcccgcag gaaattggcg ttttcatagt gtgtactgtt gctcattgtg gagcctcccg
     1201 ggctgatacg tcgatatgaa ggagtttagc agggggcggt ctgaaagaat atgctcgtgt
     1261 cagtcaggct gatgaagacg aaagctggta aaaaagggct tacgacaccc attttacgtc
     1321 aaactgcacg acatgcagtt gcgtgcatag ccatgcagcg ggttaaaatt tatcaggcgc
     1381 gtttccggcg gttttccggg tggtttgttg ccggttttat cccgtagccg ccggaaatgc
     1441 cctcagaccg tctgagcggt gcgcgtaatg cgacgttatg gtaaatcatg tgattaatgg
     1501 tagtgataat cattatcact tttgctatat tcttgtttct tttattgtaa ggaaatgtaa
     1561 gtatggcaat cacgattaaa tccgccgtta atgtccgtag cagagtatta atatactctt
     1621 tactactgtt tactggttca gcgtatgcgg ctgatatagc tgaatcaaca ttcctgactc
     1681 gtgatatcgg caatggtctg tatgaaatgt cttttgatgg caaaaataat agtctctggg
     1741 cagcatcatc gtcttcattc gacagagata agggccacgg aattgtttat cagttagaac
     1801 catccactct gaaaacaaaa tctgccgtta aaatcgcacg tcttgggttt gccacagcac
     1861 tggatgagga acatgagcga ctttatatcg gcaatactct ggacggctca gtgacggtca
     1921 ttgatactct aaccggaaaa gaactttcag taattccgtt aactgaggga caggatgagg
     1981 ctcatttcag accgaccaga gaaatggtca ttgacaaaaa aaatcagcgt ctttatgtct
     2041 ccagcgccgc agataaaggg gctctgtggg ttattgacat ggctgtcggg aagaaaatta
     2101 aaaccattga tggactgggg cacgctgtta ctggaattgc gttaaataaa aatggggata
     2161 atatttatct ggttaacggg gatggtgaga ttattaacct ggatgccagt agctatgaaa
     2221 taaaaaaacg gtttgttgta gagcctgaga aaaaacactt tttccttaat gtaagtctgg
     2281 atgaaaaaaa cggacgtgca tttattaccg acccggatat tcccggggtg ctggttgttg
     2341 atgtaaactc gggaaaaata ctacacagaa ttgatgttat aaattcactg gcgattttat
     2401 ttaatccttt acggaacgaa atctatatca cgcaccgtaa tgcaaaacag gtcagcattg
     2461 tggacagtaa ttcttattac gtaaaaacaa cgataaaaac ccgcctgatg ccaaacagtc
     2521 tgtctttatc acatgacggt gaaaatctgt acgttagtgt aaaacaagaa aaaaaagaga
     2581 tgagtactat gaaggattac atactcaaaa tcgaattatc taaaattgct atggagccag
     2641 aagaatgaat aaatatttag ggctgagcat agtatatatg atgtatacat catctgttat
     2701 ggctgatgat tctggcgcag ttagtaaaga taaaaatatt tcaccagaag aaacattaat
     2761 tgttcatggg accgctgttt ctgaaagcac aacagaagga acagattcat acacaaccca
     2821 gtcagccaat acagcatcaa agatgaatct gtcattccgg gatacacctc agtcaactac
     2881 agtcattacg cgacgaagaa tggatgatgt agcagcaaaa aatattattg atgtggttaa
     2941 aaccgctcct ggattatatg tcagtacagc agaaggttcc ggaagaccga attttatgtc
     3001 cagaggattt aatgctaatg tcatgtatga aggatttagc ctgccgtgga attcatacat
     3061 tccaagttca caaactagtt cagctatttt tgaccgggtg gagatagtcc gcggggcaac
     3121 aggtcttgtt cagggtgccg gagacccttc agccgcgata aatatgatac acaagcgtcc
     3181 gacccggcaa tatcaggcca gcactaacat cggtgccgga cggtggaatg actaccgggg
     3241 tggggttgat gtatcaggac cactgaatga cagcgcgacc ttacgcggaa gggcagttgt
     3301 ggatggcgaa aacagtgaga ccttcaggga tagtgagaaa cgcaggaata acgtcattta
     3361 cggaattatg gaggcagatc tgactgataa taccctactt acgattgggg gatatcagca
     3421 gtatgaatat aacaatcatt ggtggtatga cttacctatt tctggtaccg gacaccacct
     3481 taatcttcct cgctcgacgt ttacaggcaa tgactgggag tttgaaagaa gtaaaagtaa
     3541 aactgcattt gcaactcttg agcagaagtt cagtaatagc tggaagctga aattttcaac
     3601 gctgcaaaac tggagaaatg ctgacctgtt agggacggca acataccggc ataaagatac
     3661 ccgacaaagt atgtatcagc aagtatgggg atcactgagg gaatataatt ccaaaagcta
     3721 tgacctgtcg cttaatgggg actatgcttt atttggtcgt gttcatcaat tcgtggctgg
     3781 aacaactcag caaaaataca ccgataaaga tacaggttat acatattccc caatatatat
     3841 tgagaatgtt aatatatttg atcatggttc acattcttcg aaaaaaccca tgaagatgtc
     3901 aggtgatgca tcctacgacg tcactgaaca aaaaagcgcc tacgcagcaa ctcattttct
     3961 acttagtgat aactggaaaa tattgctggg tggccgtctt gactggtatg aatatacaag
     4021 taaaggtaca tccattaata caggttataa agttaccaga aatatcacca aatatgcagg
     4081 ttcaacatac aatcttgacg atcatcatac catttatggg agctataccg atatattcaa
     4141 tccacagtca agcaccgacc tcaatggtaa agtgatcaag cctattgttg gtaagaatta
     4201 tgagacaggt attaagggtg agtattttaa cggcttgctt aatgcctctc tggcggtatt
     4261 tcaggtagac caggaaaatc gagccaggct gcttcccgat cagacagggt gtgttactaa
     4321 tggcaatcct caatgctatg aggctagcgg taaagtacgc acaaaaggga tagatttcga
     4381 acttcagggc atggttacgc cactctggga aattggggtg ggatatacat atgcagatac
     4441 gcgatatata aaagatggag atcgtagtaa tgaaggcaag cgattcaata ctgccgtgtc
     4501 gccacaaaat ttatttaaga tttcgagcat gtacaccttt gacggaaaat taacaaactg
     4561 gcgagcagga gtaaacacgt actggcaaag taaaatatat gctaacataa cagacacaag
     4621 ggatggcaat ccggttatta ataaacaaaa ggcttattca acaactgaca ttattattgg
     4681 ctatactcca atgccacaac tggatttaca gctcaatata actaatgtct ttgataaggt
     4741 ttattataca tccataggtg aatcgattgg atatggcacg gaaacatatg gagaaccaag
     4801 aaatgttaaa attagtgcaa cctatagatt ctaaccatgc ggattgggtc ttctcctcgg
     4861 atttgcccct ataaatccgt cttttgtggt tccggcgtac aaccccctgt ttgccacttc
     4921 agttgatggt taatcaaatc atgtagagga tcttcttgag atcctccatg gttcgtcgta
     4981 atcttttgcc ctgtaaacga aaaaaccacc tagggaggtg gtttgatcga aggttaagtc
     5041 agttggggaa ctgcttaacc gtggtaactg gctttcgcag agcacagcaa ccaaatctgt
     5101 ccttccagtg tagccggact ttggcgcaca cttcaagagc aaccgcgtgt ttagctaaac
     5161 aaatcctctg cgaactccca gttaccaatg gctgctgcca gtggcgtttt tgcgtgtctt
     5221 tccgggttgg actcaagtga acagttaccg gataaggcgc agcagtcggg ctgaacgggg
     5281 agttcttgct tacagcccag cttggagcga acgacctaca ccgagccgag ataccagtgt
     5341 gtgagctatg agaaagcgcc acacttcccg taagggagaa aggcggaaca ggtatccggt
     5401 aaacggcagg gtcggaacag gagagcgcaa gagggagcga cccgccggaa acggtgggga
     5461 tctttaagtc ctgtcgggtt tcgcccgtac tgtcagattc atggttgagc ctcacggctc
     5521 ccacagatgc accgaaaaag cgtctgttta tgtgaattct ggcaggaggg cgaagcctat
     5581 ggaaaaacgc caccggcgcg gccctgccgt tttgcctcac atgttagtcc cctgcttatc
     5641 cacggaatct gtgggtaact ttgcgagagt tagcagcgcc cgccgcagtc tcacggccgg
     5701 agcgtagcga ctgagtgagg gaggaggcgc aatatccccc ctcccgcaga cggccaccgg
     5761 acgcgcggat gtgacatatt gcaccgtgtt accgcctttc ccttccctgc cgataaatca
     5821 ttcagatagg tgaagtctgt cggttttctg ctgaatattt tacgttaacc tatctctgtt
     5881 gcttttttct ccttgcggag aaatgcaggt catccccgct ggggcgtggc tgacttcagg
     5941 aggaaatccc ctgcttacgc tggctggacg ccaccgacgc acggtctttc cccctctttc
     6001 tggctcagct cggctggacg ccggccacgc cagaaattca cccggccccc gtcaggctca
     6061 cgcctgacca cccacaaaaa cccacggtgc tgaacgcacc tgacgaagca gcaaagctgc
     6121 tcctgatttt gcgggtggtc agccgctcgc tatggcgaac tctgacgggg ccggaacacc
     6181 ggaaaagacc gcactggggt gccgcctttt cctctcacac gctggggcgt gctcgttgtt
     6241 cctccggggc tgcgcctttt ccgcttgggg cggaaagagg ctggcctccg tggtgaaagc
     6301 tgaatgcaat caccacggac gtgaccgccg ccgccatgcc tcggggcatg tccgcggctt
     6361 gtgcagcagg ggctgcacac cacgccggta aacccgtcgt ctgaaggaga gagattgcat
     6421 gtttaatacg gattcgcttg cctggcagtg gcatatcccg gagctggccc ggcagattta
     6481 cccgtgggtc agctggctgt acagggagta ttacggtctg gccggggctt tcctggttat
     6541 cggcctgttt ttcggtctgg ctgaactctg ggccggacgg atgcgttttg tggggctgag
     6601 tcataaggag cgacgggagt atgccgatcg ctataagcgc gataataacc ggactgcgcc
     6661 attttcggtg ctggcttcgc tggattcgcc cgggcggatg gtcagggcac ggcggcatgt
     6721 ctggaactac gcgtactggc tgaccggcgc tgccggtctg gcccttctgg gggggctggt
     6781 tgtcgccgtg tttatcgaga gctggggaga aaccgtcctg cgtccggacc tctacgcgaa
     6841 cgcagattat tacctgctgc agccggctaa cctgttcggg attgtctggt gtgccggagg
     6901 gcttgtcgcc ggcatccttc tggcgcggct gctggcattt ctgctgcttg acggtcattt
     6961 tgcggccgct gacgaggcgg tgaatgcgaa actgaaccag gagagccggc gcagcagcca
     7021 gcggaccgga gaaatgaccg acgtccgcca cctgcatttc ggggagccgg taccggttaa
     7081 cgcgctggcc gatttttcca cagagcaggc ccggaaacag caggcggtgt ttctgggtaa
     7141 ggatgagcag ggccagccgg tgctggtccc gcgtgatacc tggcgcaaga ccaatattca
     7201 gatcctcggc ctgcccggga gcggcaagag cgtgatgggc accaacgcgc tcattcgctg
     7261 cgtacgcgat ttcggggacg cggtggtgta cttcgacccc aaaggggacg cgtgggcgcc
     7321 gcacgtcttc cgggcgcact gcccggactt caccctgctg gatctgcggc cggggaaacc
     7381 ggcgcagctg aatctgtttc gcgatctcga ccagtacgcc ctgaagaatc tgctggttgc
     7441 cgggtttaac ctgagtgaga ccggcgacgt ggcggaccac taccgcatca gcgagcagaa
     7501 agcggcgaag ctgattgcgg agcagttccc gcagggggca aacattcagc aggtgctggc
     7561 ggcggcatac gcgctgccgg aggccctgaa aaaggacgtg aaggggctga tcaccaagct
     7621 ggagaacgtg gccgacctga gcgtcctgca gacggacagc ggcatcgacg tggcggggat
     7681 aatcaacggc ggcggctgcc tgtacgtcat cggctcgatg gacgatgagg cggtgatccg
     7741 ggtgcagaag atgctgtttg cccgctgcgc gcaaatcatc attgcgcggg atgagttccg
     7801 gaggtggccg cacgcgagca tcatgctcga tgagattaaa tacctgctgt cgaagtacgt
     7861 gctgaacgcg ctggggacgc tgcgcagtcg ggactgcaac ctgctgctcg cgcaccagtc
     7921 gctgggcgac ttcgggcagt gcggccagga tctgcccgct gagtttgtga aaaccacggt
     7981 gctggataac acgccgatcc gctggttcta ccgggcggcc agccaggagt ccgcgcagtg
     8041 ggcggcgggc cagaccgggg aaatccgggt ggacgtggag cgccgccggg ccagccggga
     8101 ggcggggaac gtggagcata tcagcgggga cagcttcatt cagaaggagg cgcggccgct
     8161 gtttgacgtg aacaccctgc agcacctgcc tgacgggttt gcggtgatga ccgggctggg
     8221 cgtggcccgg atggcgttca gcagcccgct gcgggttgaa cgccgggaaa tcccgctgca
     8281 gcgcttcccg gtgctggcga aaacggaccc gctggcggag taccagccgg aggccgggcg
     8341 gcagcggccg ggtgatgatg attttgcggg gctgtactga tggcactgga gcgatacaac
     8401 gtcagccacg cgaagcggca ggcgcggaac gcggagaaaa cccggctgac cctgcgctgg
     8461 ctgcgggaag agctgtgttc cacggcggag ctggttgcgc gacggctggg gattgcggcg
     8521 gtgcagccgg tttaccgctt cctggacagc ctggtggcga aagggctgct ggtccgggcg
     8581 aaatacccgg ttgacggccg tcaggtcagc gtgtggggac tgacgccgca cggggtggcg
     8641 ttctcgttcg acgaggacga accgctgacg gacgttattc cgtttcagcc gtcaagggtg
     8701 tcggcggcgc agctgccgca ccggctggcc gtgcagtccc tgcgtctcgc catggaggcc
     8761 cggggggcct ccggctggcg gtacctgcac cgtatggccc tgaaggggat gaaggtgccg
     8821 gacgcgctgg cggagctgga cggcagaacg gtggcgtttg aggtggagcg caccgtgaag
     8881 agccgcaggc gctatcagga ggtggtgtcc gggtatctgt tcaatcgcaa agcgaacggc
     8941 atcgatgaaa tctggtacat ctgcccggac cgggcgacgc aggtcagggt gcagcgggcg
     9001 atcctgtcgg tggatgaaat cgtgaatcca cagaccggcg aggcccgcaa aacggcggag
     9061 ctggaccggg agcggctgtt tgcgtgcttt aaatttatga caacggagtg agggattatg
     9121 gcgctgtaca tggtatttat tgaagacgcg gaggaccggg acggcgagcg ctgcatcatg
     9181 ccgaccagcg agcatcttga agatatggtg gtgctcgcct ggcagaccgg ggcgtatgtt
     9241 ttctgttttg tcgaccgggc ccagcatctg gcgatgatga aatccatcgg gatgtatgac
     9301 gagcggctca acagcgacga aaaagccacg tactttttca ccggtaaaaa tccgcaatgg
     9361 gaacgggaca aacccgcagg aatgaagctg tgtgattacc tctatcgcaa ggtggagcgg
     9421 ttcgccatcg agaacggtgt gcaggtggtt gatgccggga agtgctcacc ggagcagatt
     9481 agcgcgatga ttgaggtggt cagcgagcgg cacggggaaa gcgcggtgaa cgagaagctg
     9541 aaagcggagc tgatgcggga atataacagc cgctatttta acgtgccggt gcctgaactg
     9601 ccggaggaca aacccgcccg ccggtggtgg ccgttcggca aaaaataaac ggcagcaccg
     9661 gccatgccgg tgctgttatt ccttcccgag cttatcccgc atcacctgcc agagtgtttc
     9721 cgcatcctc
//
