LOCUS       CP031371               21845 bp    DNA     circular BCT 22-MAY-2019
DEFINITION  Klebsiella pneumoniae strain KpvST101_OXA-48 plasmid pKpvST101_4,
            complete sequence.
ACCESSION   CP031371
VERSION     CP031371.2
DBLINK      BioProject: PRJNA483246
            BioSample: SAMN09729079
KEYWORDS    .
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 21845)
  AUTHORS   Turton,J.F. and Turton,J.A.
  TITLE     Virulence genes in types of Klebsiella pneumoniae associated with
            antibiotic resistance
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 21845)
  AUTHORS   Turton,J.F. and Turton,J.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-JUL-2018) Healthcare Associated Infection &
            Antimicrobial Resistance Division, Public Health England, 61
            Colindale Avenue, London, London NW9 5EQ, United Kingdom
REFERENCE   3  (bases 1 to 21845)
  AUTHORS   Turton,J.F. and Turton,J.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2019) Healthcare Associated Infection &
            Antimicrobial Resistance Division, Public Health England, 61
            Colindale Avenue, London, London NW9 5EQ, United Kingdom
  REMARK    Sequence update by submitter
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 02-JUL-2018
            Assembly Method :: miniasm v. 0.2-r168-dirty; racon correction (3
            iterations) v. 1.3.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 293.0x
            Sequencing Technology :: Oxford Nanopore MiniION; Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/21/2019 15:23:05
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 4.8
            Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region
            Genes (total)                     :: 6,176
            CDSs (total)                      :: 6,055
            Genes (coding)                    :: 5,577
            CDSs (with protein)               :: 5,577
            Genes (RNA)                       :: 121
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 87
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 478
            CDSs (without protein)            :: 478
            Pseudo Genes (ambiguous residues) :: 0 of 478
            Pseudo Genes (frameshifted)       :: 334 of 478
            Pseudo Genes (incomplete)         :: 141 of 478
            Pseudo Genes (internal stop)      :: 62 of 478
            Pseudo Genes (multiple problems)  :: 51 of 478
            ##Genome-Annotation-Data-END##
            On May 22, 2019 this sequence version replaced CP031371.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..21845
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="KpvST101_OXA-48"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="pKpvST101_4"
                     /geo_loc_name="United Kingdom"
                     /lat_lon="51.64 N 0.40 W"
                     /collection_date="02-Jun-2018"
                     /collected_by="Hospital in South East England"
                     /note="genotype: ST101"
     gene            join(21845,1..2524)
                     /locus_tag="DWR33_28760"
                     /pseudo=""
     CDS             join(21845,1..2524)
                     /locus_tag="DWR33_28760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004848462.1"
                     /note="frameshifted; incomplete; partial on complete
                     genome; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /name="tape measure protein"
     gene            2690..2974
                     /locus_tag="DWR33_28765"
     CDS             2690..2974
                     /locus_tag="DWR33_28765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017146453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QCS89690.1"
                     /translation="MTNDEKQKLYRAWADDIGGGIPFPDACRDMTCGATTRKGTPCKMT
                     ALYASGRCKLHGGMSTGAKTPEGKARQLEGFRRWLERKRQATSQGAGSH"
                     /name="hypothetical protein"
     gene            3179..3550
                     /locus_tag="DWR33_28770"
     CDS             3179..3550
                     /locus_tag="DWR33_28770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004848464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QCS89691.1"
                     /translation="MGIKGRGMNNIRRNINALVKDIAGRRAYRAVQAALQEGSLVAALY
                     TPIDTSTLINSQYREVVARGTRITGRIGYSANYAIYVQDPAIPQTFRRSTAKKEFLQKG
                     IEDAKPQMVAAIVRELSKR"
                     /name="hypothetical protein"
     gene            3721..4380
                     /locus_tag="DWR33_28775"
                     /pseudo=""
     CDS             3721..4380
                     /locus_tag="DWR33_28775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017146451.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            4582..5122
                     /locus_tag="DWR33_28780"
                     /pseudo=""
     CDS             4582..5122
                     /locus_tag="DWR33_28780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016244020.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid pRiA4b ORF-3 family protein"
                     /name="plasmid pRiA4b ORF-3 family protein"
     gene            complement(5115..5476)
                     /locus_tag="DWR33_28785"
                     /pseudo=""
     CDS             complement(5115..5476)
                     /locus_tag="DWR33_28785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004202368.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            5920..7187
                     /locus_tag="DWR33_28790"
                     /pseudo=""
     CDS             5920..7187
                     /locus_tag="DWR33_28790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001303105.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4102 domain-containing protein"
                     /name="DUF4102 domain-containing protein"
     gene            7195..8148
                     /locus_tag="DWR33_28795"
     CDS             7195..8148
                     /locus_tag="DWR33_28795"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QCS89692.1"
                     /translation="MRPDKNIKSRILPLEFCDLQKASSMLGCSVDDLFHWAEINAISLS
                     LRLDYFPSFLSFDHVGGKDSAELFESLISEYNQVTLSVERRVSYFMPDMNNPEVYRDGN
                     RIHVKGWAFGLWAIRPNRIRELSSVGQIELNEALVVDQHMDLYIKHDIRAFLRAENVFR
                     EKTLPILVRPSHGDPNPEEIINAINKKIEYHTISKDDVLLSRHWIKKLHDCIENNEGIY
                     NSFDLDGFSYEEKEIFDINNVHGNVEISARKREEVYKAAIYWLLNDPESCKGKKGDITQ
                     QAWAKRIVEGRHEKPISLGEDKIIKCLREAMKGDKN"
                     /name="hypothetical protein"
     gene            8275..8493
                     /locus_tag="DWR33_28800"
     CDS             8275..8493
                     /locus_tag="DWR33_28800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004866314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlpA family phage regulatory protein"
                     /protein_id="QCS89693.1"
                     /translation="MQEQETLSVTIPSSGYIRRFRLAQHLGIHVATLDRWVRDKHIPSP
                     VKLGEKITAFNAVEINKWLAERRGKVA"
                     /name="AlpA family phage regulatory protein"
     gene            8490..8837
                     /locus_tag="DWR33_28805"
     CDS             8490..8837
                     /locus_tag="DWR33_28805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016535037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QCS89700.1"
                     /translation="MMKKNRPGQQAANNIDIRGSDVTPPAPTTQAPRRTPKKHRARELE
                     RRLDIQIERIDEKNPDGIGSHLRYRFTGRGDVLKVIRLVNHNATAGGYNGLSKRDIADI
                     LNLYPDNLTAA"
                     /name="hypothetical protein"
     gene            8851..9643
                     /locus_tag="DWR33_28810"
                     /pseudo=""
     CDS             8851..9643
                     /locus_tag="DWR33_28810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004177036.1"
                     /note="frameshifted; incomplete; partial on complete
                     genome; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="antA/AntB antirepressor family protein"
                     /name="antA/AntB antirepressor family protein"
     gene            9727..10260
                     /locus_tag="DWR33_28815"
     CDS             9727..10260
                     /locus_tag="DWR33_28815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001580982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirepressor protein"
                     /protein_id="QCS89694.1"
                     /translation="MQAEESDISVIKFEGYTVRIVNVYGEPWFVVSDVCQTLEINNPTS
                     AVSSLDCDEVMTLTLTEGHSGKRGGARSWNMAAESGFYKLIARSRKASTPGTFAHRFSN
                     WVFRDVIPSIRKTGSYGVPFAFLNDHTRRKELCTKKASKRGRDLQSCKMMKARLAAEEI
                     ELWRKYQPDLLEVH"
                     /name="antirepressor protein"
     gene            10260..10439
                     /locus_tag="DWR33_28820"
     CDS             10260..10439
                     /locus_tag="DWR33_28820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014837681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4222 domain-containing protein"
                     /protein_id="QCS89695.1"
                     /translation="MVKTTSTPLPNHSYRDAHGQMVSVTAVAHNRVTFYRQGYQFPCVQ
                     PIERFMKEYTEVKQ"
                     /name="DUF4222 domain-containing protein"
     gene            10436..11394
                     /locus_tag="DWR33_28825"
                     /pseudo=""
     CDS             10436..11394
                     /locus_tag="DWR33_28825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014837682.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /name="HAD family hydrolase"
     gene            11391..11708
                     /locus_tag="DWR33_28830"
     CDS             11391..11708
                     /locus_tag="DWR33_28830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004177032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinol-cytochrome C reductase"
                     /protein_id="QCS89696.1"
                     /translation="MSLYNDLVRHEFGKGVTADELESIQNRKDEAVSDLMLGISAIGSL
                     MFWATDNGNYTEETAKGDMRKIGAMLGTVGEVVLALNDTAANAGVCRSDCGKESKVRSA
                     K"
                     /name="ubiquinol-cytochrome C reductase"
     gene            11705..11968
                     /locus_tag="DWR33_28835"
     CDS             11705..11968
                     /locus_tag="DWR33_28835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016244015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinic acetylcholine receptor subunit beta"
                     /protein_id="QCS89697.1"
                     /translation="MNINAIYRHPAEQEAEAMLSRVQPYPEDFTLAERTAERMTRARNG
                     LAHVMTDLATQLSDEQAEIVYCWLSKVLTIVDMARIDAEGSA"
                     /name="nicotinic acetylcholine receptor subunit beta"
     gene            11965..12225
                     /locus_tag="DWR33_28840"
     CDS             11965..12225
                     /locus_tag="DWR33_28840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004866297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QCS89698.1"
                     /translation="MNTVAVIEPETIPTGDATAAVRYASELLELWNLYLDGPLRAANPL
                     YGARLATLITELRCATIRTERKVNRLADELTKMREYREGSA"
                     /name="hypothetical protein"
     gene            12222..12433
                     /locus_tag="DWR33_28845"
                     /pseudo=""
     CDS             12222..12433
                     /locus_tag="DWR33_28845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020801597.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            12430..13055
                     /locus_tag="DWR33_28850"
                     /pseudo=""
     CDS             12430..13055
                     /locus_tag="DWR33_28850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020801598.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            13070..15842
                     /locus_tag="DWR33_28855"
                     /pseudo=""
     CDS             13070..15842
                     /locus_tag="DWR33_28855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016244017.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DUF927 domain-containing protein"
                     /name="DUF927 domain-containing protein"
     gene            16181..16429
                     /locus_tag="DWR33_28860"
                     /pseudo=""
     CDS             16181..16429
                     /locus_tag="DWR33_28860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016244018.1"
                     /note="incomplete; partial on complete genome; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /name="single-stranded DNA-binding protein"
     gene            16653..16895
                     /locus_tag="DWR33_28865"
     CDS             16653..16895
                     /locus_tag="DWR33_28865"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QCS89699.1"
                     /translation="MELDLVSVVKFALEGEDKDLRIYLAKHIRGLRKSDPLLAKTLEEL
                     LKNHPARSHQVMRRDTSTFDYSDDESNGYATLPKT"
                     /name="hypothetical protein"
     gene            16990..17769
                     /locus_tag="DWR33_28870"
                     /pseudo=""
     CDS             16990..17769
                     /locus_tag="DWR33_28870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014620858.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /name="AAA family ATPase"
     gene            17766..19970
                     /locus_tag="DWR33_28875"
                     /pseudo=""
     CDS             17766..19970
                     /locus_tag="DWR33_28875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002117386.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /name="S8 family peptidase"
     gene            20446..20764
                     /locus_tag="DWR33_28880"
                     /pseudo=""
     CDS             20446..20764
                     /locus_tag="DWR33_28880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016831732.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="superinfection immunity protein"
                     /name="superinfection immunity protein"
     gene            21468..21794
                     /locus_tag="DWR33_28885"
                     /pseudo=""
     CDS             21468..21794
                     /locus_tag="DWR33_28885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004140789.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
ORIGIN
        1 cacgtttatc ttcaagttca gaggaaggtg cgcggagttt tcagcagctt gtaaatattg
       61 cctccgcaac tggggcaagc ctaggtgata ccgtcaacct ctggcagcag ctcaccgcca
      121 cactgaaaac cgtaggtgct actaacagcg atgttaaccg acttgtgatg acgctgcaga
      181 agattggcac tattggcggc tcatcagctc aggaaatggc taatgcgcta aggcaattta
      241 tgcagtcggt agcatccggc agaattcagg ctgaagagtt taactcagtg ctggagcaga
      301 tgcctgagct agcgaggcag attgccgatg gcatgggaat tccatttaat gagctccgcc
      361 agttgatgct ggccggcaag ttagatattg gtgaagtgct agcggcaatc gaaaagcggt
      421 ccgatgaaat caaccagcag tttgagacta tgccgcgcac tgtatcgcag gcaacaaatg
      481 ctttgattac tcagttcggg gtagctatat ccaaaattga tgatgctatc ggtgggtcgc
      541 gctatttggc aaaacttctc gaccaaactg ccctttctat ctccgtagcc accggaaatg
      601 tagatcctat tgttgcgata gatgcgcagt tggattctct gaataaaaaa ttagctgtaa
      661 ctgaagcagc ttacaataca gtttccaaag cttctatcta cactgacgca ggtactaaaa
      721 cacaaataga tgctatcaaa ggtcaaattg ctgccctcga acaagctaaa tctctttatt
      781 ctgatattgg gaaggtggca tcaggttctg tagatggatc taagccagct tatatcacca
      841 atctcgaaaa gaaaactgca gagaacaacg ccaattcgat cattaaatct ggccaaacag
      901 tagttgataa gcttacccag cagcgcgagc aattaagcaa agacaaggcc aaagggctga
      961 ttgacgataa gaaatatgct gatgctgctg ctgttctgga taagcaaatt gccgaagcca
     1021 agaaaaagca ggataagcct gcgaagaatg cctttgctcg cggcgacgat tcaatcgaca
     1081 acctgcagcg gcagattgcc gttttgacaa tgcgctatga cgagaacacc agagaggccg
     1141 cacagtttaa tgccgtggcc gctctcggag ctaaggctac cgatgcacag aaggaaagag
     1201 tgcgtgagtt ggccgggcag ttatttgacg ctcagcagcg ccagaaagac cttaatgatg
     1261 cgattagcaa tgaccccgtg cgtaaggaaa ataaaactta ttcagatggt cgagaccagc
     1321 taaaacgtca actagacggc cagatgattg accagaaaac ctataaccag caatctgagt
     1381 taatggagca gcagcatcaa gtcaatctgg caaaaatccg tgctcaggag caaacagcaa
     1441 acccgatagc agccgcccgc gctgaagttg acccagtaca gcaactggta aacgagaacg
     1501 accagaagct tgccctgatg aggcagtacc agcagcagga acaggcaata ctccagcaga
     1561 gctatcaaca gggaaaaatc agttatgatc agttcatcgc tgccaaatca gctacggatg
     1621 ctcagtatct ggccctgaga acagcccagg agaaccagtt caacgagcag atgacagcag
     1681 cgcagtggca gctattaagc cagcagagcc tcggctataa catgctgacg agtgctgtgg
     1741 acgcctttag cggtaatgcc tcaaacgcaa ttactgggct actcactggc acaatgtcag
     1801 cacaggaggc aatgaggtct cttgggaata ccatcctgaa cagcgtgatc aacagcattg
     1861 cccaggtggg tgtggagatg ctgaagaact tcatcctgtc tcagacattg ggcgcggcgg
     1921 ctcaagcggc aaatgctgcg tctgccattg caggaggggc tacggcactt gcagcttggg
     1981 cgccagcagc aattgccgcc tcaattgcca ctgggggaac agcctcggcg acaggcttaa
     2041 ccgcgtatca gggggcgcaa gccgccggat tggcaacaag tgtgctcggt ggccgcaaaa
     2101 atgggggccc tgtaacagcc ggcggagtgt accccgtagg cgaaggaaac ctaccggaac
     2161 tcatgcagac cagtaaaggg ctgttcatga taccggtgat gatggcccag tattcagcaa
     2221 caaggatgta accagcggag ctccgaccat caagaaggca tcaaccggta aagaatatct
     2281 cccggcatcc tcagcatcat ccagccaggc ggaaagccgc actgaacgac cgatacaggt
     2341 caacataacc cttatcgacc agaccaccgg caaccagcac aacattactg gcactgaagc
     2401 tttccagcaa ggtgacgtgg taacagttac tggatttctc aatgacgtgg ataccggcgg
     2461 cccaatgtcc acagcgatcg cagatgcgca cgggcttaga cggcaggcaa ggggcgcctt
     2521 ttaatgtgcc ctaagggggg aggtaaaccc tctcccccat gctttacagg actgccagtt
     2581 taagagcatt ttcacccgtc ggaaataaga actttttttc gcgtgaacgc agccagtata
     2641 caacctaccc catgagaggg tgacaaagtt gacatcgaaa ggcgatcccg tgactaacga
     2701 cgaaaagcaa aaactatacc gtgcgtgggc tgatgatatc ggcggcggaa tacctttccc
     2761 ggacgcctgc agggatatga cgtgcggagc gacgacgagg aaagggacac cgtgcaaaat
     2821 gacggcgctc tacgcttctg ggcgctgcaa gttacacggt ggcatgagca ccggcgcaaa
     2881 gacgccggag ggtaaggccc ggcaattaga gggattccgc cgctggctgg agagaaagcg
     2941 gcaggccacc agccaaggcg ctggttcgca ttgaggttcg caccgaaaac ggctttaaaa
     3001 tattggactg tactggacgg atttaaaacg cgggcattct taaacccgcg ccagtagcgg
     3061 gctaagaaca acaatgagac ttgagccgtc aaagttttta ggttcgcagt acgcagcacg
     3121 gtacgcagca aaatgaaggt tttttcagtg cgtaccagac agagataagg ggtgataaat
     3181 gggtatcaaa ggcaggggaa tgaacaacat tcgccgcaac atcaatgcgc tggtgaaaga
     3241 tatagccggg cgccgggcat accgcgctgt tcaggcagca ttgcaagaag gttcgttggt
     3301 cgccgccctc tatactccga ttgataccag taccctgata aattcacagt atcgggaagt
     3361 tgtagccaga ggaacgagaa taaccggccg tatcggttac tccgcaaatt atgcaattta
     3421 tgttcaggat ccggctatac cgcagacgtt caggcgttcg acggcaaaga aagagtttct
     3481 gcagaaaggt atcgaggatg cgaagccgca gatggttgcc gctatcgttc gcgagctgtc
     3541 aaaacgctga tatcggaaaa acggaactga tacttgcgca tcagatactt accccatgag
     3601 tagttaacaa ttgttaaggt tctagcgacg attattaggc cgtattcgca gtaaccaatt
     3661 gtgcagaact catataattt cgtattcatt tggggatttt tttagcggag atctgagcca
     3721 atgagagagc agacgcgggt ttacacctct gcgctaccac gaattaacct ccagtttctg
     3781 gcaaatctgc aaagcaagct ggtggattcg agcccgaaaa cacacatttt tgtgataccg
     3841 agagcggaag gtgtacttct cgatggtctc tggtggctac agcgcgacaa tcaacggggt
     3901 agcgcgggtt attggcatca cgatcacccg ggtaggtttt ggctatcggc gatggtacat
     3961 ttgcccgcat tgtggtggcc gggttgcgaa attatttatt ggccggaagg atgtagggtg
     4021 tcgtaaatgc tggagccttc actatgccag ccagagtgaa gatgagatcg ctcgcttacg
     4081 gcgcagtgtg tggaagcaga ggcatgatat atgggggatg attacccacc cgcgggcagc
     4141 ctgctaaata gcccgctcaa gtttccgaag cctgccggca tgagatggga taccttcgag
     4201 aaaaagcgct ctcgactgct aaagactgaa tcagcttact ggcggctgaa agaaccgagg
     4261 gacgctaaag ggtttgctcg ggtgatacgc aaagtggagg cgtcaattcg gtcatttgaa
     4321 cgggcatcga aaaggctacc ccatgagcac gctaagattg ccctaacgct taccccatga
     4381 tcacggcacg ataaagagcg ccaccgccgc aggttgagcg cacaagccta ccagtggaag
     4441 aagccagcgc cgcgcaggta gatacgggat tattccgcat gtaacttatg cttattaagc
     4501 aaattacctt tattcacctt tacagaattg tgagtgcgtc agtatcgtta tccttccgat
     4561 tcgcatttat tcaggatttg catgtaccag ctaaagataa ccatccgaga cagcaaacca
     4621 ccaatatggc ggcgtgtgct ggttccagag caaatcccct ttagtgaact tcacgcggtg
     4681 atccagttgg cttttggctg gaatgacgaa catctgtata tgttcgagaa aggccgtaaa
     4741 ggtgatctag gtagcgagta tcgcgtatgg ggtgagggtg aaagcatgga taatgcggca
     4801 atcacgccac tatgggcggc gatccagaat gaggggtgac aagctggttt acgtatgact
     4861 ttggcgactg gtgggattgc cttattgtgc tggagaagca aacacatgat accagcatcc
     4921 agcctgttag ctgtttgcgt gggagggact acccggcgga aaattcaggg ggggattgca
     4981 tggttacaat gaattgctct tacaggccag agaatctgat aatcctgaac aggccgagat
     5041 acgcaatttc cttatgctgg atattgaacg ccgggtttac gacctgaaca gcattaacga
     5101 cagattgcag gctcttaact gacccgccag cattccccat caatcgcttt atcagcgccg
     5161 ccattatcgc gcacaacggc acactgtccg ggtaaaccgt agcgcacgac cgttgcgcta
     5221 gtctcaccgc tttttttttt atctgccggg attcgtacac tgtcacccgc tcaagcaacc
     5281 caccagcaac catactttca agagttcgcc gggttgattc tagctggtgg cgcttatcga
     5341 acgacgccat gccatgaaga aggtaggcca cgcccgacac atcgaacggc ggcgtaccaa
     5401 tctcacccgt cacccattcg aggttatccg gctcaaagta gctgagtatc tcttttttgc
     5461 ggctggtcat tctcatggct gggggattcc ttattgtggg atagatgtat catacaataa
     5521 gaatggtaac ggcaagattg cgacgatgct caagtttgcg tgaaagaggg gagcaccttc
     5581 taaaatcatg tacacatggg tgtacacaaa ataattatca aactttaaat ttacatataa
     5641 aacaatgtac ttatgggttt tattgtcttt cacatcaaga aaagcaaata agctatcagg
     5701 acgattcacc caccagcaca aaacacccaa agcccgcatc tgccgggctt ttttgttatc
     5761 atgggctatc ataaaggcgc aacaaagcgc atgattggcg tgtacacaga ggtgtaccca
     5821 tggtcattag ccaaagtttt gggtatacct ctaagcaatt tgggtacatt tcgcggtgta
     5881 cccaatggat cacggtaagg atttttcagg tattcgcaca tgccaaaact tacagacatg
     5941 cagatccgcg catggattaa gagcggggaa cgcttcgagg ggcgagcaga cggtgacggc
     6001 ctctatctga ggtttcgaaa agaggataaa actccttttt ggcgctatcg atataagctg
     6061 gtggggaagg cacgcaccat gatgatcggt tcttattccg atttctcact ggcaaaagcc
     6121 cgagatatag cgaaagagct atccgcgcgg gtagcgctcg ggtatgacgt agccgcagag
     6181 aagcaggagc gcaaggctga ggcaatagcc aagattgagg ctgagaagaa cgccattcac
     6241 gtttcagagc ttgccgctga gtattacgcc cgccagatag aaaccactta caaacacccg
     6301 gaacttttcc gcagcagcct gcaaaagaac atcgttgcgc tcatcggaaa gatgaaagta
     6361 gaggacgttc gcccgcggca cattgatagc gtcctgcagg atgttttaga gcgcggatct
     6421 cccacggtag ctaatgatgt acttcgcatg ctcaaacgcc tgtttgatta cgctgtggta
     6481 cgcggaatga tagaggttaa cccggcgata tcctttggct ccaaagacgc tggcgggaag
     6541 gagcaggggc gcaaacgtgc gttaagccgt gatgagctga ttatgttctt caaggcgcta
     6601 cgccgagggc gcggaatcag cagagagaat gagctgacct tcaagattat tctggcgctt
     6661 ggggtgcgca aaatggagct ctgtgccgct gaatggtcgg aattcgacct tgataacgag
     6721 gtgtggcacc tccctggctc gcgggcaaag aatggtgatg acatcgatat cccgctgcgg
     6781 cgccagtgat cgaatggatt aaagagattc gacttttcgc cggtgatagt cgctggttaa
     6841 ttccggccag gcgcgccaga acaacggccc acgttagccg tgccacgctg aatatggtta
     6901 tgccgtctgt actgaaagag atggctgacg ttgagccgtt cagtatacat gacctgcggc
     6961 gaaccatgcg cacccagatg gccgcgatag gcattgaccc ggtgatagcc gagcgttgcc
     7021 ttaaccataa aataccgggc atagagggta tttataaccg tcaccagtac tttgatgagc
     7081 ggaaagcggc gctggcgcag tgggcgaatc tgctggtggc cttagaaact ggtgaagatt
     7141 ataacgtgac gccaataagc atcgcgatga acgcgtcagc taaatgagat tattatgaga
     7201 ccagataaaa acatcaagag cagaatttta ccactagaat tttgcgatct ccaaaaagcc
     7261 agtagtatgc tgggttgttc agtcgatgac ttgtttcatt gggctgaaat taatgctatt
     7321 agcctttctc ttaggcttga ttatttccca agctttctat cctttgatca cgtaggtggg
     7381 aaggatagcg cagagctatt tgaatcacta atttcagagt acaaccaagt tactctaagt
     7441 gtcgaaaggc gcgtttcata cttcatgcct gacatgaaca atccagaagt atatagagat
     7501 ggaaatagaa tacatgttaa aggatgggct tttggcttgt gggctattag gcctaataga
     7561 atcagggagt tgagttctgt tggtcagata gagcttaatg aagctctcgt tgttgatcag
     7621 catatggatt tgtatattaa gcatgacatt cgcgcctttc tcagggctga gaatgtattt
     7681 agggaaaaaa cactccctat attggttaga ccttctcatg gtgaccccaa ccctgaagag
     7741 attataaatg ccattaataa gaaaatagaa tatcacacaa taagcaaaga tgacgtgctt
     7801 ctttcaaggc attggattaa aaaacttcat gattgcattg aaaataatga gggtatttat
     7861 aattcatttg atttggatgg tttctcttat gaagagaaag aaatttttga cattaataat
     7921 gtacatggaa acgttgaaat atcggcacgt aaaagagaag aggtttataa agcagcaatt
     7981 tattggcttt taaatgaccc tgaatcgtgc aaaggaaaga aaggtgatat tacacaacag
     8041 gcctgggcaa agcgcatagt cgaggggcga catgagaaac cgatatcctt gggtgaggac
     8101 aagataataa aatgtctgag agaggctatg aagggtgaca agaactgata tcaccaggct
     8161 aataaaatat taacctacaa aaacaaaatg gcgtcactta tcaaccattc ctcatgatgt
     8221 atagcataag ccctgtaacg acgcataaac cgaaacagag gggttacagg gcatatgcaa
     8281 gagcaagaaa cacttagcgt aacaattcca tccagtggtt acattcggcg cttccgcttg
     8341 gctcagcacc tcggcattca cgtggccacg ttggatcgct gggttcgcga taagcacatt
     8401 ccatccccgg ttaagttggg ggaaaaaatc actgctttta atgcggtaga gattaacaaa
     8461 tggctggcag agcgccgggg aaaggtggcc tgatgaaaaa aaaccgcccc ggacagcagg
     8521 cggctaacaa catagatatt cgcggatctg atgttacgcc accagcgccc accacacaag
     8581 cgccacgccg cacaccgaag aagcaccgcg cccgcgagtt agagcgcaga cttgatattc
     8641 agattgagcg tattgacgaa aagaatcccg acgggatcgg gtcacattta cgctatcgct
     8701 ttaccgggcg cggtgacgtt ctaaaagtta ttcggcttgt gaaccacaac gccaccgctg
     8761 gtggctataa cgggctttct aagcgggata tcgcggacat tctcaatcta tacccggaca
     8821 atctcaccgc cgcataacgg agccgaaaat atgactatcg aaaaaagccg atacagttcg
     8881 ggggccgccc cgcaacccaa cgttaacacg gggtaattaa cggcaacgac tttgccgcta
     8941 ttgttcccgt tattgccgga cgcattggcg ggcgtgaaat aatattgcga gcgccagagc
     9001 cttgcataag gcgctggggg tgggccgcga ctttactaac tggattaaag gccgaattga
     9061 ccagtacggt ttcattgccg gaaccgattt tatccgtgtt gaaaatttga gcacgccaaa
     9121 acgggcgagc gcaaaatttc gccagcaaat cgagcatgat taccttctct cgctggatat
     9181 ggctaaagaa gtggcaatgg ttgaacgcaa cgagcagggc cgcgccgttc gacgttactt
     9241 cattcagtgt gaggaagcac tacagcgcag cgtgccagag attgccgctc tgtatcgccg
     9301 ccagctaaaa gcccgtatca gtgccgccaa cctgtttaaa ccgatgtgcg tagcgctgga
     9361 aagcgcccgc gcagaacagg gtaaacagac gctggctcgc cactacagca atgaaagcaa
     9421 catgatcgcc cgtatcgtgc tgggtggcat gacggcgaag cagtgggcgc aagtgaacgg
     9481 tatcgaccgc gaaccgcgcg atagcatgag tgccggccaa ctggagcacc tcagctacct
     9541 agagagcacc aacatcacgc tgatcgatat ggggatggag tacggccagc gtaaagcaga
     9601 gctaatccgc ctgtctcagc ggtggctggc aaagcgtctg gggtggctca tgactaagca
     9661 ttcagtgacc aaagccgagc tagtcacaat gcctgcccct cagcctgtag ccagccagaa
     9721 agagatattc aagccgaaga gagcgatatt tcagttatta aatttgaggg gtataccgtg
     9781 cgcattgtga atgtttacgg tgagccgtgg ttcgttgtat ctgacgtctg ccagacgttg
     9841 gaaatcaaca atccaaccag tgccgtttcc tctctggatt gtgacgaggt aatgacccta
     9901 actttaactg agggtcattc gggtaagcgc ggcggggcac gtagctggaa tatggccgca
     9961 gaatctggct tctataaact gattgcccgc agccgtaaag cctccacgcc cggtacgttc
    10021 gcccaccgct tcagcaactg ggtattccgc gacgttatcc cgtccatccg caaaaccggc
    10081 tcctacggag tgccgttcgc attcctgaat gaccataccc ggcgcaaaga gctgtgcacg
    10141 aagaaagcca gtaagcgcgg tagagacctg cagtcgtgca agatgatgaa ggcccgcctt
    10201 gctgctgaag aaatcgagct atggcgtaag tatcagccag atctgctgga ggttcattaa
    10261 tggttaagac caccagcacg ccgctgccaa accattccta tcgcgacgct cacggccaga
    10321 tggtgagcgt gaccgctgta gcgcataacc gcgtgacgtt ctatcgccag ggctatcagt
    10381 tcccatgcgt acagcccatt gagcgcttca tgaaggagta cacggaggta aagcaatgat
    10441 taccgccgcc cggtgcaaaa gcctctctct ggctggcctg atgtatgcaa agttaacgct
    10501 ctgcaggcgg tgcgccaccg tgggaacctg tcaaaacctg tcattctgtg ggccattgat
    10561 agtggctctg ttgaagtgta tttcgagaca agtaagcgcg cgggtaagcg ttcggaaact
    10621 gactatctgg aagatagcgt gtccggcgcc ggcggtagat gcggggccca tcacaccgcc
    10681 agctataaat tgccgcgccg tgacaaaaag ggcttgcggt ctgaaggtat cccggtctat
    10741 ggttatagcg caccagcaaa atctggtgcc gggattagcc tcccggacat gatcgaggcg
    10801 acacatgacg cgccaagcgt ctttttttgt gtcgttaact cagtacaccc ttttttcagc
    10861 gatgcggtta taatccgtgc cgctatcaaa attatggtgg gctgtgtagg ggcttcttcg
    10921 gaagcgccgg gttccttgat caccggtaag gctaaccttg cacagttcac caccagacag
    10981 attagcctct gcggtggtgg atatattcca ttgatcaagg aggcggccaa atggctacta
    11041 cccctaccca aattccgcaa tttatctgga ttatcgccgc tgttcgccgc gatatgccga
    11101 caattaccgc aaaaattcac catatcgccg caccttctga gcgtgaagcc cgccgttctc
    11161 tggttcggga tcacgtctgc tttttcgctg gtcgcatccg tctggaggtg gctcatgcgt
    11221 aactatttcc gcatcaccgg ctacgccgtt aataagcgcg gtttaacggt tggtatcggc
    11281 tatcagctca catccagcga caccaaaaca gcaacggccc acgcagtgct tcaggcgcag
    11341 cgtgaaggtc tcagccatgt gcgcattacc cgcgttcggg aggtggctgc atgagcctgt
    11401 ataacgattt agttcgccac gagttcggca aaggcgtcac cgctgatgag ctggaaagca
    11461 ttcagaaccg caaagacgag gccgtgagtg atttgatgct cggcattagt gccattggca
    11521 gcctgatgtt ctgggctacg gacaatggca actacaccga ggaaaccgca aagggagaca
    11581 tgcgcaaaat aggcgcaatg ctgggtacgg ttggtgaggt ggtgctggcg ctgaacgata
    11641 ccgcagcgaa cgcgggtgta tgtcgttctg actgcgggaa ggaatcaaag gtgaggtcag
    11701 ccaaatgaat ataaacgcta tataccgcca tcctgccgag caagaggccg aggcaatgct
    11761 atcccgtgtg caaccttatc cggaagattt tacgctggca gagcgtaccg cggaacgcat
    11821 gacccgcgcc cgcaatgggc tggctcacgt tatgactgat ttagccactc aactaagcga
    11881 tgaacaggcc gaaatcgtgt attgctggct gagtaaagtc ctgacgattg tcgatatggc
    11941 cagaattgat gcggagggca gcgcatgaat acagtcgccg taattgaacc agaaacaatc
    12001 ccgacaggtg acgcaacggc agcggtgcgc tatgccagtg aattgcttga gttatggaat
    12061 ctttatctgg acgggccatt acgtgccgcc aatccgcttt atggtgccag acttgcgaca
    12121 ttaatcaccg aattgagatg cgcaaccatt agaaccgagc gcaaagttaa tcgcctggct
    12181 gatgaactaa cgaagatgcg cgagtatcgg gagggcagcg catgagcaag ttatccctga
    12241 ttgattcagc ctgccgtatc aagcaagcgc agcaagttct ttctctttgg cttgaagcac
    12301 cgattaaaaa gatagcggca cggatcatct tattggcgca gtcattaccc ttctggatgg
    12361 tatccccgag atgatggatt cagtagaagg cgagttagtt gatatggatt tgagtctgga
    12421 cggcaaagca tgagcaacgt agagaaattc acaccgggaa atgacgacgt attacgcgcc
    12481 gaagccacac cgcacggcgt caatatcatg acccgcaatg atgccggggg atttgagctg
    12541 gttgctctta tcagctacga gagcgccgtg aacggccttg acgccggaga gtacgacgac
    12601 aagccagata tcggatacgc catacatttt gccgttgctg atggcggggc gcgtggctgg
    12661 ttcgacttta ccgcgcagca taacgtcact atgtggcgct ggctgattgc tgcgacgttc
    12721 atttctgaga tgaagcgcga aaacggcaca accaccatca cggaggatga cggcaaatcg
    12781 tcgctggtga cgttttattc aaatggcacg gcggggattg tggtttaccc gttcgcggaa
    12841 cgtctggcga tggctaacaa catggagggc gcaatgattg agcgctacgg cattgagcag
    12901 ggaacagcga acgccattgt tttttatcag gccatgatcg acacggagcg cgggaattga
    12961 ccccgttcgg gcgtgaaacg ctggcagagc tacacgatgg attcattgcc gatctgaatg
    13021 aaaacggctt gcctgaaatg ccagcggcgc actgagggag gtaacacgaa tgcgtaatat
    13081 cgaccttatc cgcgaagtga ccagcgccgc agcagggcga tggccttatg tgctggccgg
    13141 attgtctatc gacgttcctg attcatcgcg ccgccatgcc ccctgccctg catgtggtgg
    13201 gaaagaccgt ttcagattcg acgacaacgg gcgcggcagc tttatctgca accagtgcgg
    13261 cgcgggcgat ggcttagacc tgattaagaa ggtgaacaac tgcgacacca cggaggcggc
    13321 acaccttgcc gctgatgtgc tgggtattga ttaccgggcc gcagaatcag caccagacgc
    13381 tgccagccag agacagaggc agttagccgc agaccgccag cagcgtgagc aggagcgcca
    13441 gaaacaggca gcagaggacg cagatcagcg aagggctacg tttgcccgtc tgtataccgg
    13501 aatgcgcctg agatccatac agggagaatc tgagtacctg caatcaaaag ggctgaccgg
    13561 gtttaaatac ccgcttatgc ccgatggttc gttattgctg gagctggtgg atgaatccgg
    13621 cgcagtcaca gccgcgcaga ccatcacccc gcagggagaa aagcgactca ttaagggatc
    13681 ggcaaagcgc ggggcatatt acgccgtaaa cgcgctggaa cggcctcaaa gcgtcgtgat
    13741 tgccgagggg ctggctaccg ctctaacgtg tcacttaatt cgcacagacg cgctgacagt
    13801 ggcagcaatc gacgcgggca acctgctgcc cgtcgccgaa gtcatgcgcc ggaagtaccc
    13861 acaggcacaa atcatcatcg ccgctgataa cgaccaccag caaggaggcc ccgaaagtgg
    13921 gggcaccaat acgggcaaag aagccgcaga aaaagccgcc ttatccgtgg ctggctgggt
    13981 atcgctgccc ccgaccgaca acaaaaccga ctggaacgat taccaccaac agaacgggct
    14041 ggaagccgct acagcagcct ttaacgattc gatgtatcaa ccgcagggga aagcgtgaaa
    14101 ccgcagttac aggccattga gggcggtaaa tccggccagc cagaaagatc cgctgaagcc
    14161 gcacgttgag agccgcgcag acggcgtttt ctgggttacg ccgaaagtgg ataaggacag
    14221 cggcgaggtt atcaaccggg aggcgtggtt atgttctccg ctggaggtgg taggtaccgg
    14281 gcgggatgat aaagaccagt acctgattat ccgctggcag gcattcgggg tcagcgctct
    14341 cacgacggcc gcaatccccc tggctgatat tggcgagcgt gaaggctggc gcaccctgaa
    14401 ggcgggcggg attaacgtca ccaccaaagc agcctgcgcg cgatccttgc cgactggcta
    14461 cagcgcagcg gcgcgcggga gctgtggcgc gttgcccacg cgacgggctg gcagtgcggg
    14521 gcatacatca tgccggacgg cgaggttatc ggaacgccgg aacatccggt gctgttcaac
    14581 ggccgcagct cggcggcggc cggctacacc gtcaaaggca ccgctgagga ctggcgcggc
    14641 agcgtggcgc acctggtagc cggtaactac tccatgatga ctgcgaccgc cgcagcgctg
    14701 gcggcgccgc tgattggcct ggcgggtgcc gatggcttcg ggatccactt ctatgagcag
    14761 tcgagcgcgg gcaagaccac cacggcgaac gtggccagca gcctgtatgg caacccggat
    14821 ttactgcgtc tgacgtggta cggcacggcg ctggggctgg cgaacgaagc cgccgcacac
    14881 aatgacggcc tgatgccgct ggatgaggtc ggacagggat ccgacccggt aagcgtgtcg
    14941 cagtctgcct atgcgctttt taacggggtg gggaagctgc agggtgcgaa ggagggcggc
    15001 aaccgggact taaagcgctg gcggaccgtg gcaatcagca ccggcgagat ggatttgaaa
    15061 ccttcatcgc gggcgccggc cgcaggacca aagccgggca gctggtgcgg ctgctgaata
    15121 tcccgctgag taaggcggtt cacttccacg agcaccggaa cgggaagcag catgcggatg
    15181 cgctgaagga ggcataccag caccaccacg gcgccgctgg gcggctgtgg attaagtggc
    15241 tggccgacca ccagcagcag gctacagaag ctgtccggga gtgtgaggcc cgctggcgca
    15301 gcctgatacc tgcagactac ggcgagcagg tacatcgcgt aaccgccggg ttcgctattc
    15361 tggaggcggc gttgctgctg agcgccggca tcaccggctg ggatgcacag acctgccggg
    15421 atgcggtaca gcacagctat aacgcctggc tgcgggagtt cggcaccggc aacaaagagc
    15481 atcagcagat catcgagcaa acggaggcgt ttcttaacgc ctacggcctg agccggtttg
    15541 caccgtttcc ttacagcccg gccgacctgc caataaaaga actagccggc taccggcggc
    15601 gccaggggga acacgacgag agcccgatat cgttctatac gttcccggca acgttcgaga
    15661 aggaaatcgc cgcgggcttt aatcacaagc agtttgccga agtactgaaa agagcgggaa
    15721 tgctgacgcc gccgagcagc ggacgcggat atcagcgcaa gtctccacgt atccagggga
    15781 ggcagatcaa cgtttacgtc ctcaactacc tgccggagga ctacaaccag ccagaggaat
    15841 agtatttctc acatacgagt aaagggtttt ggttcagttg gttcagttgg ttcagtaatt
    15901 aaaggttact gttttataag cattttaatt atgaatctga accaacactg aaccaacaaa
    15961 tgcctgtttt gaaccaacgc cggcgcgtag agttttttcc ctggcaggcg gtgaaccaac
    16021 agaatgcccc gctgaaccaa cgcaaaattg ctgaagttgg ttcaggaaaa cccagtaacg
    16081 gcgcgggctg gcgggcagtg aaccaactga accaactgaa ccaacactat ttctgtttat
    16141 tatcagaaaa aaacagagac tggccgagag agagatgagc atggcagcac aaatttcagc
    16201 atacgggcgg ctggtggccg accctgagac ccggacaacg ggaaaaggta cgagcatggc
    16261 tatggcccgg ctggcggtat cgctgccgtg caatgccgca gcggacgggc aggctacctt
    16321 ctggctgggc gtcattgcct ttggcaagca ggcggacgcg ctggctaaaa accgtaaagg
    16381 cgacctcatc agcgtggaag ggaatataca gcttaatcag tgggctggat aaggcagcac
    16441 aattaccggg aagaggctag caacaccgct ttaatgcctt tctcaggttg agcaatacac
    16501 tctaatttgc actgtaaaaa acacagttcc tactgacttg ttcaattgtt atggctataa
    16561 tgaggaatca tgtgaaaact agtcattgct taactttcta gttttttact ttaaatcaac
    16621 gtgttgtgct tttttgtgcc taaggtgttg caatggaatt ggatttagtc agtgttgtca
    16681 agttcgctct tgaaggggaa gataaagacc tcaggatata cttggctaaa cacattcgtg
    16741 gattgagaaa aagcgatccg ttgttggcta agactcttga agaactgctc aagaatcatc
    16801 ctgcccgatc tcatcaggta atgagaagag atacttcgac atttgattat tcagatgacg
    16861 aaagcaacgg atatgccact ttgcctaaaa cttaattaaa gaacaaccaa taagtaatgg
    16921 cagtaatgag ccattgttac aattgcaagt taagaagcag ttgaagcaag tgatccggaa
    16981 aggaaaaaga ttgatttgtt tgcacgtcat ggacttagtc ctacaaagtc tcttattttt
    17041 agtggccctc caggggtcgg taaaacaatg actgctcaat ggttatcgtc cgagttagac
    17101 attccattat atactcttga tttaactacg gttatgagta gctttttagg taaaacgggc
    17161 agtaatctaa gaagtgttat tgattatgct aaatcccatc catctattct tttattggat
    17221 gaaatagacg ccatagcaaa aaaacgtact gatgagtcag atgttggtga actcaaaaga
    17281 ttggtaacga tcatgcttca ggagctggaa gagtggccaa gcactggttt atttgttgct
    17341 gccacaaatc acccagagtt agttgatcct gcattatggc gtcgctttga ttgtgaaata
    17401 gtttttggat taccaacaga tgaacaagtc agtgatgcta ttaaattatt ttccggggat
    17461 gacttcaaaa tattcgagcc gtggttcgat ttacttaaag atagcttgca tggacagtcc
    17521 tacagcaata tcaaacgtga aatctaccag ctgcgaaggc tacatcttct taaatctgat
    17581 gagtttgagt cagatctcat ttcccatctc aactttgact taaatggtaa gtctaaaagc
    17641 tgaacaaatt agctttgctg taaagttagt taaaaatatg gttttacgca gcagaaagct
    17701 tcaaaagttg cgaatgttag cagggacact atccggaaga gattaacaga gcaggagtac
    17761 acacagtgag tgataaaaaa aattacatta ttggtaaggc tgaagagtta acatcattaa
    17821 cgccgccacc taaaataaaa tctaatgtgg atcctatcta tacctttact gaggttatta
    17881 gaaggctcga gccacaattt gagataacga cacagcaact taatgcctta agcagtgacg
    17941 tttgtccaag ggattttgct gtaagtgcaa ttaccttgca tccctcttat attgctaaag
    18001 gccatttccc aagaacattg ttcagagaaa tgggcgttcg ctcattgggg agtaaaggta
    18061 ttgaagtctt gccagataaa tggactcagg taggtcctcc taaaaatcgc caaccacaaa
    18121 aatatttata gcaggaaaac gtgagactta ctgagtttag tgaaaattta cgtagtctct
    18181 cagaagacag ccctggtgct tcggatcttt ttcgtgtttg gagcatagaa aaagttgatg
    18241 aacgtgacaa aataaaagaa aaccccaatg cctttgaagg gtattgggaa gttggtttgt
    18301 agctcattcc aggagggaat tccgaattta ttaaatcttc attttattag ctatgcatca
    18361 gaattggggt ttgagctcaa agaaaacatg gctattgaag tttcaaacct ctggttttac
    18421 caatagctgg agaagaaaag attttttaga gcgattggct gctttctctt ttgttagggt
    18481 tgttcgcccc cctcccagca atgcgttctt tttcgaccgc tgactagaaa taccccaatt
    18541 ggggcagatg tcgatttacc taacgtacat ccatatgctt ctgatgtgcg tgtagccatt
    18601 ttggactgcg gattacctga taagcatgta ttagaaccat gggtatcaaa ttatggtctt
    18661 tctgacccaa cagcaaatga tctcaccgac ggtccctctc atggcttagg gagttacatc
    18721 ggcctttctt tttggaccgt tgtggcctgg tgaaaaagca cctcgcccgt tttcatatgt
    18781 agatcattac agagttttag atgaaaaggt tgaagggaag atccctatga gctttataga
    18841 acactttctc acctagaaga tattcttctc tctaggcaat atgagtttat gaatttaagc
    18901 ttgggcccag atttgccaat tgatgataat gaaatacatc catggacctc tttaattgat
    18961 acctatcttg ctgacggtga gacagttctt acgattgcgg cagggaacaa tggcgaaagg
    19021 aaccgtgagc ataaattaaa tcgtgttcaa gttccctctg attgtgtaaa tgccctttca
    19081 gttggggcaa tcaatagagt tgaatcagac tggaaaagag ctacttatag tgcggttggt
    19141 ccaggtcgtt caccaggctt agttaaacct gatcttgttg ctttcggagg tgatcctaag
    19201 cagtattttc acgttcccag cgatactagc attgggaaat tggtcccaac ctgtgggacg
    19261 agtttttcag caccttatct tttacggtat gcagttggtg ttcgtgcgat tttaggacat
    19321 gatgtatcgc ctttggcaat taaggccttg taaataaatt ctgctaatca acattctaac
    19381 gacaaggaag aggttggttg gggaaaagta ccagattcta ttaatcagat tattgaatca
    19441 gcggatggta ccgctaaaat tttatatcaa ggagagttat accctggtaa gtatttaaaa
    19501 gtaccagttc cgatgcccgc aacagggatt attggtaagg ttaaaattaa agcaacatgt
    19561 tgtttctcaa gccctgtaga ccctcaagat acttctatgt atacaaaggc aggtgttgag
    19621 attacttggc gaccaagtcc tgataaaacg gacccatttt ttaaacagaa aacggttgct
    19681 acagaagctg agttgcgtgc tgatgctggc aaatgggagt ctgttttaca tggagagaaa
    19741 ggtaagttgg gcactagtct tgatcaacct tgttttgaaa tccactatat ggctcgtgat
    19801 ggtggggatc agatagcaga gctaaagcct ctattattag atatgccttt gtagtctcaa
    19861 tagaggctcc caaaacgcca gatatcttca atggcatctt aaggtctgat gcgaaactgg
    19921 ttgaaataca acctagaatt cccgtaccga ttcctgtttc atttaactaa agaatggccc
    19981 ttatcgaggg ccattttttg atgcccagtt tatctatagc tttggaaagt tcaattaccg
    20041 tgcgtggaca gtcggaaaag caggtgaatg ctattttcgg cacggcccca tgaaaatgcc
    20101 tatatcttat ttataggcag aaacggtgtg ttctggctat gtatggcagg aatggtgtgt
    20161 tatgcccata gataggcaat cttgatgagt tcttcctata aggactgata gcgctcgaaa
    20221 atggtcgttg agacgggctg tggcggaaga tagttaagcg cccaccagcc tctgcagaag
    20281 atttcggagg ccttcacaaa ccgctaagga gactaggcac cgcatgggga ttactcagtc
    20341 aaacgccgag gcgttcaggt taaaacaagc cgatgaaggt gaatgtattg gattaatctt
    20401 cttcgatgtt acgataatac tttatttact tttggggata agttgatgtc agtatggaac
    20461 atcattgttt tgatattcgc tattatcatt tatgttcttc ccggcgttat agccagttca
    20521 agggagcata aaaatgctac ggcaatttgg gtgctaaata ttgtcttggg ctggagcttc
    20581 ttgggttgga tagccgcgct tgtctggtct ttcacaaacc ccggtggtta agcttgaacc
    20641 acaggtgttt ggcgcggatt ctgctggtgg cggttcagta gacgatacta aaaaatgtcc
    20701 gtattgcgcc gaaacaataa aaaaagaagc aatattgtgc cgattttgtg gcaaagattt
    20761 ataaatcgac atcgtcaagc aagggtggca tcaatgaaaa ttattatggt attaatttca
    20821 tcacttttat ttctcacggc atgtaagcct acatgaagag aaagccatag agttggctaa
    20881 aagcgagata tcgcacgaca tgaaagatcc atcatctacc caatttagag atgttgtgtc
    20941 aaaaaaaaaa gttggtgaaa aggatgatgg ctctatcgca atcttgtctg tggtgaggtg
    21001 aactcaaaga acagctttgg ggcatattca gggtactcgc cttttgtcat tgcgctaacg
    21061 atgaaatcaa agggtttttt ctcttccggt gttgtgtacg tagttgaagg gaagacagta
    21121 gatgatcttc caacaagcac gaatagtgca aatacgatta accctgcaaa gtaacctcaa
    21181 ggcaaacccg ctccggcggg tttttgtacc tttcatttca taaattgcaa atgcttgcca
    21241 ttttatgttg cataaactac aatataaatt gactgtataa atatcagggg taagcagatg
    21301 aaccgatcgc aaatcacggt agcactttgc cgggagcatc ttcagtccat tcgtgaaatt
    21361 caggaagagg agcgcaagcg ttctccgatt ggtgtagcac caacggtaaa cgctattgcc
    21421 cgcgcattgg ttgctaaggg tcttgaatcc gttaagcggg gtgggtgatg gagcaactac
    21481 agagattggc tgaggtgatt gccgaaacct atatccgcga tctgcgccgg gaaacgggta
    21541 gcaacgttct taccgtggat ggcgttagcg ggtgtgtcaa gccctctact ttcagccgga
    21601 cttgttgata acgctgtgag tgcgtccaaa gataagtttg actcggcctt cgagcgtaag
    21661 gcctatcgaa tgttgatgga gtttatttct tttgatggcc cagagtatcg gcttactgag
    21721 catggtcgcc atgtaattac agtcgcgaac accatatccc tgagaaaaaa aataaggtaa
    21781 taaccatcca ttgaggagta cgacaacagg cttcggcgat taagcacgat agagattgag
    21841 gcgga
//
