LOCUS       CP031370               19229 bp    DNA     circular BCT 22-MAY-2019
DEFINITION  Klebsiella pneumoniae strain KpvST101_OXA-48 plasmid pKpvST101_3,
            complete sequence.
ACCESSION   CP031370
VERSION     CP031370.2
DBLINK      BioProject: PRJNA483246
            BioSample: SAMN09729079
KEYWORDS    .
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
REFERENCE   1  (bases 1 to 19229)
  AUTHORS   Turton,J.F. and Turton,J.A.
  TITLE     Virulence genes in types of Klebsiella pneumoniae associated with
            antibiotic resistance
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 19229)
  AUTHORS   Turton,J.F. and Turton,J.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-JUL-2018) Healthcare Associated Infection &
            Antimicrobial Resistance Division, Public Health England, 61
            Colindale Avenue, London, London NW9 5EQ, United Kingdom
REFERENCE   3  (bases 1 to 19229)
  AUTHORS   Turton,J.F. and Turton,J.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (22-MAY-2019) Healthcare Associated Infection &
            Antimicrobial Resistance Division, Public Health England, 61
            Colindale Avenue, London, London NW9 5EQ, United Kingdom
  REMARK    Sequence update by submitter
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 02-JUL-2018
            Assembly Method :: miniasm v. 0.2-r168-dirty; racon correction (3
            iterations) v. 1.3.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 293.0x
            Sequencing Technology :: Oxford Nanopore MiniION; Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 05/21/2019 15:23:05
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 4.8
            Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region
            Genes (total)                     :: 6,176
            CDSs (total)                      :: 6,055
            Genes (coding)                    :: 5,577
            CDSs (with protein)               :: 5,577
            Genes (RNA)                       :: 121
            rRNAs                             :: 9, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 87
            ncRNAs                            :: 9
            Pseudo Genes (total)              :: 478
            CDSs (without protein)            :: 478
            Pseudo Genes (ambiguous residues) :: 0 of 478
            Pseudo Genes (frameshifted)       :: 334 of 478
            Pseudo Genes (incomplete)         :: 141 of 478
            Pseudo Genes (internal stop)      :: 62 of 478
            Pseudo Genes (multiple problems)  :: 51 of 478
            ##Genome-Annotation-Data-END##
            On May 22, 2019 this sequence version replaced CP031370.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..19229
                     /organism="Klebsiella pneumoniae"
                     /mol_type="genomic DNA"
                     /strain="KpvST101_OXA-48"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:573"
                     /plasmid="pKpvST101_3"
                     /geo_loc_name="United Kingdom"
                     /lat_lon="51.64 N 0.40 W"
                     /collection_date="02-Jun-2018"
                     /collected_by="Hospital in South East England"
                     /note="genotype: ST101"
     gene            complement(join(19027..19229,1..43))
                     /locus_tag="DWR33_28635"
                     /pseudo=""
     CDS             complement(join(19027..19229,1..43))
                     /locus_tag="DWR33_28635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016535037.1"
                     /note="incomplete; partial on complete genome; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            complement(join(19229,1..218))
                     /locus_tag="DWR33_28640"
     CDS             complement(join(19229,1..218))
                     /locus_tag="DWR33_28640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001705541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlpA family phage regulatory protein"
                     /protein_id="QCS89672.1"
                     /translation="MTASQTAQSALPTTGYIRRFRMPALLGVSMPTIDRWVKNGTLPRP
                     VKLTNNVTAFDAVEINNWLAERRGKVA"
                     /name="AlpA family phage regulatory protein"
     gene            complement(366..1238)
                     /locus_tag="DWR33_28645"
     CDS             complement(366..1238)
                     /locus_tag="DWR33_28645"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QCS89673.1"
                     /translation="MAHGKLINIWEKNTIPPLPWCSLNRAATLLKCELSDFSAWMNHLN
                     PMIEFKQSSVEGTLTVTLNNYDNPYEYGDISKEYIDLIPVASRGGLTPTSPMIDTAFTI
                     DKNKKTLDFVGYFDGMASVLEGMYLIENDELMVLPQDLFCEIPIAKLGAPYVGEDCPVL
                     SVDDILIRPVYAYCYDAQPIVLSMNDVYLSREDIELIYNCGVQGIDLPEDRLAVSESIK
                     AKPKIRETAKQSRFIAYLINALGVKQDELKTLSIKNIMDRLSHMANEIKFPDVTDDSLR
                     DWLEKAGYR"
                     /name="hypothetical protein"
     gene            complement(1353..2612)
                     /locus_tag="DWR33_28650"
     CDS             complement(1353..2612)
                     /locus_tag="DWR33_28650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016244008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4102 domain-containing protein"
                     /protein_id="QCS89688.1"
                     /translation="MPKLTDMQIRAWIKSGERFEGRADGNGLYLRYREADKTPTWRFRY
                     KLAGESRAMLIGSYSELSLSKARETAKELSARVALGYDVAGEKQERKSEALAKMEAEKN
                     AMRVSELAAEYFERQILPRWKHPDILRRRIDKDINPCIGSMKVEDVKPRHIDDMLKGIV
                     DRGAPTIATDVLRWTRRIFDYGIKRHALEINPCSAFEVADAGGKEVSRDRWLTRDELIQ
                     LFKAMRTAKGFSRQNEITFKLLLALCVRKMELCAARWEEFDLDKAVWRLPEERSKNGDA
                     IDIPLAPPAVEWLRELKTFSCNSTWVLPARKMQNRMIPPIQESTLPVALAKVRAEMPDV
                     PNFTIHDFRRTARTHLAALGVDPVVAERCLNHKIKGVEGIYNRHQYFDERRAALTQWAG
                     LLVALERGEEYNVTPLRKAK"
                     /name="DUF4102 domain-containing protein"
     gene            3038..3397
                     /locus_tag="DWR33_28655"
     CDS             3038..3397
                     /locus_tag="DWR33_28655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004202368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QCS89674.1"
                     /translation="MRMTSRKKEILSYFEPDNLEWVTGEIGAPPFDVSGVAYLLHGMAS
                     FDKRHQLESTRRTLESMVAGGLLERVTVYESRQIKSGGETSATVVRYGLPGQCAVVRDN
                     GGADKAIDGECWRVS"
                     /name="hypothetical protein"
     gene            complement(3390..3932)
                     /locus_tag="DWR33_28660"
     CDS             complement(3390..3932)
                     /locus_tag="DWR33_28660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016244020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid pRiA4b ORF-3 family protein"
                     /protein_id="QCS89675.1"
                     /translation="MYQLKITIRDSKPPIWRRVLVPEQIPFSELHAVIQLAFGWNDEHL
                     YMFEKGRKGDLGGEYRVWGEGESMDNAAITPLWAAIQNEGDKLVYTYDFGDWWDCLIVL
                     EKQTHDTSIQPVSCLRGRGTTPAENSGGLRGYNELLLQARESDNPEQAEIRNFLMLDIE
                     RRVYDLNSINDRLQALN"
                     /name="plasmid pRiA4b ORF-3 family protein"
     gene            complement(4053..4241)
                     /locus_tag="DWR33_28665"
     CDS             complement(4053..4241)
                     /locus_tag="DWR33_28665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012666442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QCS89676.1"
                     /translation="MLDRQKLELTLIEIARQNDEGVDSHTLYTIRNGVAQVLQAKERHR
                     RRMSAQAYQWKKPAPRR"
                     /name="hypothetical protein"
     gene            complement(4366..4995)
                     /locus_tag="DWR33_28670"
     CDS             complement(4366..4995)
                     /locus_tag="DWR33_28670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016831726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QCS89677.1"
                     /translation="MREQTRVYTSALPRINLQFLADMQRKLVDSSQKTQICCDTESGRV
                     YFSMVSGGYSATINGVTRVIGITFTRVGFGYRRWYICPHCGGRVAKLFIGRKDVGCRKC
                     WSLHYASQSEDEIARLRRSVWKQRHDIWGDDYPPAGSLLNSPLKFPKPAGMRWDTFEKK
                     RSRLLKTESAYWRLKEPRDAKGFARVIRKAEASIRSFERASKKATP"
                     /name="hypothetical protein"
     gene            complement(5167..5536)
                     /locus_tag="DWR33_28675"
                     /pseudo=""
     CDS             complement(5167..5536)
                     /locus_tag="DWR33_28675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004848464.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            complement(5628..5912)
                     /locus_tag="DWR33_28680"
     CDS             complement(5628..5912)
                     /locus_tag="DWR33_28680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016831728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QCS89678.1"
                     /translation="MTNDEKRKLYRAWADDIGGGTPFPDACRDMTCGATTRKVTPCKMT
                     ALYASGRCKLHGGMSTGAKTPEGKARQLEGFLRWLERQRQATSQGDNTQ"
                     /name="hypothetical protein"
     gene            complement(6066..8863)
                     /locus_tag="DWR33_28685"
                     /pseudo=""
     CDS             complement(6066..8863)
                     /locus_tag="DWR33_28685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004848462.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /name="tape measure protein"
     gene            complement(8860..9201)
                     /locus_tag="DWR33_28690"
     CDS             complement(8860..9201)
                     /locus_tag="DWR33_28690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004213174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QCS89679.1"
                     /translation="MEQLQRLAEVIAETYIRDLRRETGSNIISIGGVSGNVEKHLLAAG
                     LVDNTIYAAKDEYGATFEREAYRMLMNFISFDGPEYRLTEHGRLVINLLNTNALKKKKQ
                     SKNPTLRRS"
                     /name="hypothetical protein"
     gene            complement(9508..9831)
                     /locus_tag="DWR33_28695"
     CDS             complement(9508..9831)
                     /locus_tag="DWR33_28695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016831732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superinfection immunity protein"
                     /protein_id="QCS89680.1"
                     /translation="MSVWNIIVLIFAIIIYVLPGVIASSREHKNATAIWVLNIVLGWSF
                     LGWIAALVWSFTNPGVVKLEPQVLGVESAGAGSVGDTKKCPYCAETIKKEAILCRFCGK
                     DLP"
                     /name="superinfection immunity protein"
     gene            complement(9901..10059)
                     /locus_tag="DWR33_28700"
     CDS             complement(9901..10059)
                     /locus_tag="DWR33_28700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001437066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PerC family transcriptional regulator"
                     /protein_id="QCS89681.1"
                     /translation="MVVESVLWQEMFKRPPARAEDFGGLHKAAKETQHRMGIAQPNGQA
                     FRLKTSR"
                     /name="PerC family transcriptional regulator"
     gene            10496..11446
                     /locus_tag="DWR33_28705"
                     /pseudo=""
     CDS             10496..11446
                     /locus_tag="DWR33_28705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001528727.1"
                     /note="frameshifted; incomplete; partial on complete
                     genome; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            11464..11868
                     /locus_tag="DWR33_28710"
     CDS             11464..11868
                     /locus_tag="DWR33_28710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000098670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QCS89682.1"
                     /translation="MGARTLFAIKSLFALAMAIFGARFLHDLDHNAVISAAGALSTISG
                     VLFGFVLASVTILSSFDSSKGIIGALKSNGVLKGIIEGLFGTGTTLIAACLSAMVSMFA
                     PVVSNLALDYYALLLAGAYLIISMVSFFFL"
                     /name="hypothetical protein"
     gene            complement(12104..12268)
                     /locus_tag="DWR33_28715"
                     /pseudo=""
     CDS             complement(12104..12268)
                     /locus_tag="DWR33_28715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000126714.1"
                     /note="incomplete; partial on complete genome; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /name="single-stranded DNA-binding protein"
     gene            complement(12608..14355)
                     /locus_tag="DWR33_28720"
                     /pseudo=""
     CDS             complement(12608..14355)
                     /locus_tag="DWR33_28720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001399940.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DUF927 domain-containing protein"
                     /name="DUF927 domain-containing protein"
     gene            complement(15380..16006)
                     /locus_tag="DWR33_28725"
     CDS             complement(15380..16006)
                     /locus_tag="DWR33_28725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020801598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QCS89683.1"
                     /translation="MSNVEKFTPGNADLLHAEATPHGVNIMTRNDAGGYEQFALISYES
                     AVNGLDAGEYDDKPDIGYAIHFAVADGGARGWFDFTAQHNVTMWRWLIAATFISEMKRE
                     NGTTTIKEDDGKSSLVTFYSNGTEGIVVYPFAERLAMANNMEGAMIERYGIEQGTANAI
                     VFYQAMIDTERGELTPFGRQTLAELHDGFIADLNENGLPEMPAAH"
                     /name="hypothetical protein"
     gene            complement(16003..16215)
                     /locus_tag="DWR33_28730"
     CDS             complement(16003..16215)
                     /locus_tag="DWR33_28730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020801597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QCS89684.1"
                     /translation="MSKLSLIDSACRIKQAQQVLSIWLEAPIKKDSGTDHLIGAVITLL
                     DGIPELMDSVEGELVDMDLSLDGKA"
                     /name="hypothetical protein"
     gene            complement(16212..16472)
                     /locus_tag="DWR33_28735"
     CDS             complement(16212..16472)
                     /locus_tag="DWR33_28735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004866297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QCS89685.1"
                     /translation="MNTVAVIEPETIPTGDATAAVRYASELLELWNLYLDGPLRAANPL
                     YGARLATLITELRCATIRTERKVNRLADELTKMREYREGSA"
                     /name="hypothetical protein"
     gene            complement(16469..17428)
                     /locus_tag="DWR33_28740"
     CDS             complement(16469..17428)
                     /locus_tag="DWR33_28740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014837682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="QCS89686.1"
                     /translation="MITAARCKSLSLAGLMYAKVNALQAVRHRGNLSKPVILWAIDSGS
                     VEVYFETSKRAGKRSETDYLEDSVSGAGGRCGAHHTASYKLPRRDKKGLRSEGIPVYGY
                     SAPAKSGAGIGVLVIRMATHDAPSVFFCAVSLTHPFFERWDIIQRLAKAMVAQAGASSE
                     APVSIRAGYANPAWATTSEIGVSGGSVTRYRMEAAAWLLPSPKIRNLFGLSPLFAAICR
                     QLPQKFTILPRLLSAKPAVLWFGITSAFSPDVFAQGAHMLNYFRVAGCATARSGELVEF
                     VYIVDARSAISAKVEALNQARNERLSHIQITRIREVAA"
                     /name="HAD family hydrolase"
     gene            complement(17425..17604)
                     /locus_tag="DWR33_28745"
     CDS             complement(17425..17604)
                     /locus_tag="DWR33_28745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014837681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4222 domain-containing protein"
                     /protein_id="QCS89687.1"
                     /translation="MVKTTSTPLPNHSYRDAHGQIVSVTAVAHNRVTFYRQGYQFPCVQ
                     PIERFMKEYTEVKQ"
                     /name="DUF4222 domain-containing protein"
     gene            complement(17604..18176)
                     /locus_tag="DWR33_28750"
     CDS             complement(17604..18176)
                     /locus_tag="DWR33_28750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004866306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirepressor protein"
                     /protein_id="QCS89689.1"
                     /translation="MPAPQPVASQKEIFQAEESDISVIKFEGYTVRIVNVYGEPWFVVS
                     DVCQTLEINNPTSAVSSLDCDEVMTLTLTEGHSGKRGGARSWNMAAESGFYKLIARSRK
                     ASTPGTFAHRFSNWVFRDVIPSIRKTGSYGVPFAFLNDHTRRKELCTKKASKRGRDLQS
                     CKDEKARLAAEEIELWRKYQPDLLEVH"
                     /name="antirepressor protein"
     gene            complement(18208..19013)
                     /locus_tag="DWR33_28755"
                     /pseudo=""
     CDS             complement(18208..19013)
                     /locus_tag="DWR33_28755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004177036.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="antA/AntB antirepressor family protein"
                     /name="antA/AntB antirepressor family protein"
ORIGIN
        1 caggccacct ttccccgacg ctctgccagc cagttgttaa tctctaccgc atcaaaggcg
       61 gtcacgttat tggtgagttt caccgggcgt ggcaacgtgc cgtttttaac ccatcgatca
      121 atggttggca ttgatacccc taacaacgcc ggcattcgaa agcggcggat gtatccagta
      181 gtgggaagtg ctgattgtgc ggtttgagag gctgtcatat gtcccgtaac tcctgtgata
      241 gctggtgatg gaaaggctat caatagcagt tcacaatctc gccgagtttt agaaaattcc
      301 tccgagttat gagattgttt gcttgaaact aacggcacat cttcattggc gaaaactaac
      361 cataattacc tataaccggc tttttccaac caatcccgta aagagtcatc cgttacatca
      421 ggaaatttaa tctcatttgc catatggctt aatctatcca taatattttt gatggaaagt
      481 gtttttagtt cgtcttgctt cacgcctaga gcatttatta gataagcaat aaatctagat
      541 tgctttgccg tttccctaat ttttggctta gccttaattg attcagacac ggccaatcta
      601 tcttctggta aatctatacc ttgaactccg caattgtaaa ttagctctat atcctccctg
      661 cttagataaa catcattcat actcaaaaca attggctgag catcgtagca atacgcataa
      721 acaggtctaa ttaaaatatc atctactgac agtaccgggc agtcttcacc aacatatgga
      781 gcgcctagtt ttgcaatagg aatctcgcag aacaaatctt gcggaaggac cattagctca
      841 tcattttcaa ttaaatacat cccttccaaa acggatgcca tgccatcaaa gtagcccaca
      901 aaatccagtg tttttttatt tttatcaatg gtgaatgcgg tatctatcat tggcgaagtt
      961 ggagtcaatc cgcctcgtga tgccacaggt ataaggtcaa tatattcttt tgaaatatcc
     1021 ccatactcat atgggttatc atagttattc aatgtaaccg tcagagtacc ttccactgaa
     1081 ctttgtttaa attcaatcat aggatttaga tgattcatcc atgctgagaa gtctgataat
     1141 tcgcacttca atagtgttgc tgctctgttt agtgagcacc acggtaatgg agggatggta
     1201 tttttttccc agatattaat taatttgcca tgtgccataa cgttaccttt tacgccatgc
     1261 ctttaaagtg attgagccag gcggtaaggc ttcccgcttt tcaccccgtc gggctaggct
     1321 caatctgtcc tctgattctt tacatatctt ggttacttcg cctttctcag cggtgtaacg
     1381 ttgtattctt cgccgcgttc cagtgccacc agcaagcccg cccactgtgt taacgcggcc
     1441 cggcgttcat caaagtattg gtggcggtta tagataccct ccacgccttt aattttgtgg
     1501 ttaaggcatc tttctgcgac taccggatca acgcccagcg cggctaaatg ggtgcgggcc
     1561 gtgcgccgga agtcgtgaat ggtgaagttc ggcacgtccg gcatttcagc gcgaaccttc
     1621 gccagcgcaa cgggcagggt gctttcctga atggggggga tcatgcggtt ttgcatcttt
     1681 ctggctggca gtacccacgt gctgttgcat gagaacgttt taagctctct cagccattcg
     1741 actgctggtg gtgctaatgg aatgtctata gcgtcgccgt ttttgctgcg ttcctctggc
     1801 aagcgccata cggctttatc aagatcgaac tcctcccagc gggcggcgca taactccatt
     1861 ttgcggacgc ataacgctaa cagtaatttg aacgtgattt cgttctggcg actgaatccc
     1921 ttagccgtgc gcatggcttt gaatagctgg attaactcat cgcgggttag ccagcggtcg
     1981 cggctaacct ccttccctcc agcgtctgcc acctcaaagg ctgaacatgg gttaatctcc
     2041 agcgcgtgcc gtttgattcc gtagtcgaat atgcggcgcg tccatctcag cacgtccgtt
     2101 gctatggtcg gcgctccacg gtcaacaata cctttcagca tgtcgtcgat atggcgcggc
     2161 ttcacgtcct ctaccttcat gctgccaatg caggggttta tatctttgtc gatacggcgg
     2221 cggagtatat cggggtgctt ccagcgcgga aggatctgac gctcaaagta ttcagccgcc
     2281 agctctgaaa cgcgcatagc gttcttctct gcttccatct tcgccagtgc ttcggatttc
     2341 cgctcctgct tctccccggc aacgtcataa cccagcgcaa cgcgagccga tagctctttt
     2401 gctgtctctc tggcctttga tagcgatagc tcgctatacg aaccaattag catggcgcgg
     2461 gactcccctg cgagtttata gcggaatcgc catgtgggtg ttttgtctgc ttcacggtaa
     2521 cgtaggtata aaccgttacc gtctgcccgc ccctcgaatc gctctccgct cttaatccat
     2581 gcgcggatct gcatgtctgt tagttttggc attttgcgaa tatccaaact attccaaatt
     2641 ttgaataggg ggtgtaccca aatcaatgta cacaaacctc attgggtaca cctttgggta
     2701 caccttaact atgcgctttg ttgcgtcttt atgatagccc atgataacaa aaaagcccgg
     2761 ctaaatgcgg gctttgctgg ttttgtgcgt ctttgtgata gctattaagt atttactcga
     2821 tattctggat ttgtttattg agtatcagct tcaaatgccc gtgattgctg ggtttcttgt
     2881 aatgcgtttt ctcagtgggt acacccttgt gtacacggta ttttgaggtg ctgcctttgg
     2941 ctgctcattt tatgctctca tgcttgctgt tctggcctct tatcttttgc gccttattgt
     3001 atgatacctc tatcccacaa taaggaatca gccagccatg agaatgacca gccgcaaaaa
     3061 agagatactc agctactttg agccggataa cctcgaatgg gtgacgggtg agattggtgc
     3121 gccgccgttc gatgtgtcgg gcgtggccta ccttcttcat ggcatggcgt cgttcgataa
     3181 gcgccaccag ctagaatcaa cccggcgaac tcttgaaagt atggttgctg gtgggttgct
     3241 tgagcgggtg acagtgtacg aatcccggca gataaaaagc ggcggtgaga ctagcgcaac
     3301 ggtcgtgcgc tacggtttac ccggacagtg tgccgttgtg cgcgataatg gcggcgctga
     3361 taaagcgatt gatggggaat gctggcgggt cagttaagag cctgcaatct gtcgttaatg
     3421 ctgttcaggt cgtaaacccg gcgttcaata tccagcataa ggaaattgcg tatctcagcc
     3481 tgttcaggat tatcagattc tctggcctgt aagagcaatt cattgtaacc acgcaatccc
     3541 cccgaatttt ccgccggggt agtccccctc ccacgcaaac agctaacagg ctggatgctg
     3601 gtatcatgtg tttgcttctc cagcacaata aggcaatccc accagtcgcc aaagtcatac
     3661 gtgtaaacca gcttgtcacc ctcattctgg atcgccgccc atagtggcgt gattgccgca
     3721 ttatccatgc tttcaccctc accccatacg cgatactcgc cacctagatc acctttacgg
     3781 cctttctcga acatatacag atgttcgtca ttccagccaa aagccaactg gatcaccgcg
     3841 tgaagttcac taaaggggat ttgctctgga accagcacac gccgccatat tggtggtttg
     3901 ctgtctcgga tggttatctt tagctggtac atgcaaatcc tgaataaatg cgaatcggaa
     3961 ggataacgat actgacgcac tcacaattct gtaaaggtga ataaagataa tttgcttaat
     4021 aagcataagt tacatgcgga ataatcccgt atctacctgc gcggcgctgg cttcttccac
     4081 tgataggctt gtgcgctcat cctgcggcgg tggcgctctt tagcctgcag cacctgcgcc
     4141 acgccgttgc gaatggtgta aagagtgtgg ctgtccactc cttcatcgtt ctgccgggct
     4201 atctcgatca acgttaattc aagcttttga cggtctaaca tggaagcgct cctgctcatg
     4261 gcttgtaaca ggctgatttt atttaattcc tgctcagagc cggaattaac cttgctctaa
     4321 tcgtgctgtg ctcatgggaa aggcattagg gtaatattag tgcgctcatg gggtagcctt
     4381 tttcgatgcc cgttcaaatg accgaattga cgcctccgct ttgcgtatca cccgagcaaa
     4441 ccctttagcg tccctcggtt ctttcagccg ccagtaagct gattcagtct ttagcagtcg
     4501 agagcgcttt ttctcgaagg tatcccatct catgccggca ggcttcggaa acttgagcgg
     4561 gctatttagc aggctgcccg cgggtgggta atcatccccc catatatcat gcctctgctt
     4621 ccacacactg cgccgtaagc gagcgatctc atcttcactc tggctggcat agtgaaggct
     4681 ccagcattta cgacacccta catccttccg gccaataaat aatttcgcaa cccggccacc
     4741 acaatgcggg caaatgtacc atcgccgata gccaaaacct acccgggtga acgtgatgcc
     4801 aataacccgc gttaccccgt tgattgtcgc gctgtagcca ccagagacca tcgagaagta
     4861 cacccttccg ctctcggtat cacaacaaat ctgtgttttc tggctcgaat ccaccagctt
     4921 tctttgcata tctgccagaa actggaggtt aatccgtggt agcgcagagg tgtaaacccg
     4981 cgtctgctct ctcattggct cagatctctg ctaaaaaaat ccgcaaatga atacgaaatt
     5041 atatgagtag tgcacaattg gtcactgcga atacggccta ataatcgtcg ctagaacctt
     5101 aacaattgtt aactactcat tgggtaagca actgctgcgc atgtatcggt ttcgttttct
     5161 gaacaatcag cgctttgata actcccgttg gaaagccgcc gccatctgcg gtttagcatc
     5221 agcaacaccc tgctgtagaa actctttcct ggccctgggg agggtgaatt tctgcgggat
     5281 gttcggatct gctacataga ttgcgtaatt tgctgaatat ccgatgcgtc cagtgatgcg
     5341 cgtcccgtta gtgatgacct ctttaaactg cgagttaatc agcgtgctgg tatcaactgg
     5401 cgtatagatt gcggctacga gtccggcctc atgcaaagcg gctgtcattg cgcggtaagc
     5461 gccgcccagt aatgtccctc accagcgcat tcatgttgcg ccggatgttg ttcatgcccc
     5521 tgcctttaat acccattttt cacctcttat ctctaccagg tacgcgcagc aaaaagctcc
     5581 attctgctgc gtacctttct gcgtactgcg taccatcagt gcgaacctta ctgcgtattg
     5641 tcaccctggc tggtagcctg ccgctgtctc tccagccagc gaaggaatcc ctctaactgc
     5701 cgggccttac cctctggcgt ctttgcgccg gtgctcatgc caccgtgtaa cttgcagcgc
     5761 ccagaagcgt agagcgccgt cattttgcac ggtgtcactt tcctcgtcgt cgctccgcac
     5821 gtcatatccc tgcaggcgtc cgggaaaggt gttccgccgc cgatatcatc agcccacgca
     5881 cggtatagtt ttcgcttttc gtcgttagtc acgggatcgc ctttcgatgt caacttttgc
     5941 caccctctca tggggtaggt tgtttactgg ctgcgttcac gcgaaaaaaa gttcttattt
     6001 ccgacgggtg aaaatgctct taaactggca gtcctgtaaa gcatggggag agggtttacc
     6061 tccccttaga ccacattaaa ggcgcccctt gcctgccgtc taagcccgtg cgcatctgcg
     6121 atcgctgtgg acattgggcc gccggtatcc acgtcattga gaaatccagt aactgttacc
     6181 acgtcacctt gctggaaagc ttcagtgcca gtaatgttgt gctggttgcc ggtggtctgg
     6241 tcgataaggg ttatgttgac ctgtatcggt cgttcagtgc ggctttccgc ctggctagat
     6301 gatgcggagg atgccgggag atattcttta ccggttgacg ctctcttaat gctgggcgtg
     6361 tcgcttgtca catccttgtt gctaaatacc ttcccgctat caccggggat catgaacagg
     6421 cctttgctgg tctgcatgag ttccggtagg tttacttcgc ctacagggta cactccacca
     6481 gcggttacag ggccgccatt tttgcggcca ccgagagcct tgcccgccag agtcgcacct
     6541 gaataagcag caaagccaac tccagcagca ctacccagcg tggcaatgga ggctgctata
     6601 gctgccggag cccatgccgc ataagactca gccgccgatg ccttgctggc ccccagcgtg
     6661 ctttcagcag ataaaccgaa tgcctccaat aatggcttaa cgatagccgc ctgaatcgct
     6721 gcctgcacca gtgagttaac aacgctgttg aggatggtag agccaagtga tttcattgcc
     6781 tcagaggcgc tcattgaacc cgtaagcatc cccgtgatgg cgtttgatgc gctccctgag
     6841 aaagcatcaa cggcgctggt cagggtctgc cagccaagcc cctgttgact cagtaactgc
     6901 cactgcgccg ccgtcatctg ttcgttgaac tgattctcct gcgctgtctt taacgccaga
     6961 tactgagcat ccgtagcaga tttagcagcg atgaactggt cgtaactgat ttttccctgc
     7021 tggtagctct gctggagtat cgcctgctcc tgctgctggt actgctgcat gagggccagc
     7081 ttctggttgt tttcattgac caattgctgt accgggtcaa cttcagctct ggcggctgct
     7141 atcgggtttg ctgtttgctc ctgagcgcgg atttttgcca gattgacttg atgctgctgc
     7201 tccattaact cagattgctg gttataggtt ttctggtcaa tcatctggcc gcctagttga
     7261 cgttttagct ggtctcgacc atctgtataa gttttatttt ccttacgtac agggtcattg
     7321 ctaatcgcat cattaaggtc tttctgacgc tgctgagcgt caaataactg cccggccaac
     7381 tcacgtaccc tttccttctg cgcatcggta gccttcgctc cgagagcggc cacggcatta
     7441 aactgcgcgg cctctctggt gttctcgtca tagcgcattg tcaaaacggc aatctgccgc
     7501 tgcaggctgt cgattgaatc gtctccgcga gcaaaggcat tcttcgcagg cttatcctgc
     7561 tttttttttc ttggcttcgg caatttgctt atccagaaca gcagcagcat cagcatattt
     7621 cttatcgtca atcagccctt tggccttgtc tttgcttagc tgttcacgct gctgggtgag
     7681 cttatcgacg actgtttgac cagatttaat gatcgaattg gcgttgttct ctgcagtttt
     7741 cttttcgaga ttggtgatat atgcgggctt ctccccttta gacggcgtgt aaacactttg
     7801 tgagtctttg cttgcctgtc gtgccattag gatcaatgca cgttccgcct taagcctatc
     7861 aaccgtttgc tctgtttgtt ttactcccca gcccaagccc gcctttctcg ccttagctaa
     7921 atcagactca gccacagcaa gttgctcagt attttgctca agcttttgag ttagcatcac
     7981 agcgtctgga gcgtttccgg ttgctacgct gatacttagc gcggcgccgt ctaataactt
     8041 cgccaagtag cgtgaaaccc caatagcatc atctattttt gaaactgcca caccaaactg
     8101 agtaaccaac gcgttggtag cctgcgtgac ggtacgaggc attttttcaa actgctggtt
     8161 aatttcatcc gaccgtcttt cgatcgccgc aagcacttca ccaatatcta acttgccggc
     8221 cagcatcaat tgtcgaagct cgttaaacgg aattcccatg ccgtcggcaa tctgtcgagc
     8281 caactcaggc atttgttcca gtaccgagtt aaactcttcc gcctgaattc ttcctgacgc
     8341 taccgattgc ataaattgcc tgagagcgtt agccatttcc tgagccgatg agccaccgat
     8401 agtgccaatc ttttgcagcg tcatcacgag ccggttaaca tcgctgttag tagcacctac
     8461 ggttttcagt gtggcggtga gttgctgcca gaggttgacg gtatccccaa ggctggcccc
     8521 ggttgtcgaa gcaatactca caagctgctg aaagctccgc gccccttcct ctgaactaga
     8581 ggataaacgc gttactcgcg cctgaagtag cgtgaattcc tcagaaagct gctggagctt
     8641 tatcagcgcc tgaattgata tgtatccttt cacggccaca gcaaggcgcg aaaaccctcc
     8701 gcccaagtta tccaggcttt tatctagctt gtcagcagag ttagctgttt ttgactgagt
     8761 tttcaatttg ctttaaagct gtatctgcac tcgcctgacc agccagcagt ttggccgcat
     8821 cggcttcaat ctcaatggtg tatttgccaa aatcagttgt catgagcgcc tcagtgtagg
     8881 gttcttactt tgtttttttt ttttcagagc gttggtgttc agaagattta tgactaatcg
     8941 accatgttcg gtaaggcgat attcagggcc atcaaatgat ataaaattca ttaacatgcg
     9001 ataggcttct cgttcaaatg tcgcgccata ttcatcttta gcggcatata ttgtgttatc
     9061 gacaagcccc gcggcgagca ggtgtttttc aacgttgcca cttacaccgc caatgctaat
     9121 aatgttggag ccagtttccc ggcgcagatc gcgaatatag gtttcggcaa taacttcagc
     9181 caatctctgt agttgctcca tcacccaccc cgcttaacgg attcaaggcc cttagcgacc
     9241 aatgcgcggg caatagcgtt taccgttggt gctacaccaa tcggagaacg cttgcgctcc
     9301 tcttcctgaa tttcacgaat ggactgaaga tgctcccggc aaagtgctac cgtgatttgt
     9361 gatcggttca tctgcttacc cctgatattt atacagtcaa tttatattgt agtttatgca
     9421 acataaatgg caagcattgc gttttatgaa acataaaggt acaaaaaaac ccgccgaagc
     9481 ggggttctat ttctggatga ttaatactta tggtaggtct tttccgcaaa atcggcacaa
     9541 tattgcttct ttttttattg tttctgcgca atacgggcat tttttagtat cgcctactga
     9601 accagcgcca gcagattcca caccaagcac ctgtggttcg agctttacca ctcctgggtt
     9661 tgtgaaggac cagacaagcg cggctatcca acccaagaag ctccagccca agacaatatt
     9721 tagcacccaa attgccgtag catttttatg ctcccttgaa ctggctataa cgccgggaag
     9781 aacataaatg ataatagcga atatcaaaac aatgatgttc catactgaca tcaacttatc
     9841 cccaaaagta aataaagtat tatcgtaaca tcgaagaaga ttaatccaat acattcacct
     9901 tcatcggctt gtttttaacc tgaacgcttg cccattgggc tgagctattc ccatgcggtg
     9961 ctgggtctcc ttcgctgcct tgtgaagccc accgaaatct tctgcgcggg ctggtgggcg
    10021 cttaaacatc tcctgccata gcacgctctc tacgaccatt ttcgagcgct atctgccctt
    10081 ataggcagaa cacaccattt ctgccataca tagccagaac acaccgtttc tgcctataaa
    10141 taagatatga gcattttcat ggggcggtat gattctacat gtgatgctca aacttccacg
    10201 ccgcgctgac caccagcatg aacagagcga ctaggttttg ttccaagctg agcatacaac
    10261 ctcggcaggg gtggccaaaa tcagtaaatc actacagact gattgatgaa tcactgatca
    10321 ttcatcagga tatgcgaaat ccatatgcca ggataggatg actcctaaaa accacctacc
    10381 atcaacatcg tcattatctg agatgagttt atcaatggag attttgctcg tcactagcat
    10441 gaggattttg acattaaggt gtgcgataac taactcagag taaaatggag ctcaaatggc
    10501 tgtggcagca aaagatcaaa gtttaaagtc tataagagtg ggattttata caagttctga
    10561 gaacattcgc acgaataaca aagggttaac tgcagaagcc tttaatgttc tgtataccaa
    10621 gtgttcaaaa gatctcaaga tgactcacca cgctgacttt ggcgaaagag aacttaaaat
    10681 tcatttcctt gccgtatcac ccgaagatgg ctcctacttc ggttttatgt cacggagaag
    10741 gaaaagcgcc acattagcat atattactga tactgagtgg gttgaagaga agatccctct
    10801 ggcaggagca aagtctcttt ccgagcgtac atacttcatc tactaccccc agatagacat
    10861 tttagtattg tccttaaacc acttaggtcc tcgtcatagt gacctagctt tcctgctttt
    10921 caattccagt actaacggta ccccggtttc tttgaagcca tctggaaaga agaaagcatt
    10981 aaagaactac ttgaaactgg atctaaccta agaagctgtg agatctctat agcaatccca
    11041 agaaatttca atgctgcaca gtacaatctc gatggcatgt tcgccaatca gatgattgag
    11101 atgataaaag gtactagttc aagccacctt acgctttcgc ttcgcgggca ttccccgtta
    11161 aaacgaaaag ccaaaggatg gcttgaagat gacgtcaaaa aaaagcctaa aggaaatgct
    11221 tgaaaagttc cccggcggcg atggtcgctt gacatttgag aaagctgatg ttgtcgccca
    11281 aggcgataaa aagaagaaaa gccttgtaga tgaagtactt acagtaagga aaatggttcc
    11341 tattcaaact gatggatatc cgatcgatat cgacgttaaa aatgctatgc tacaagcgaa
    11401 aaatgacaac ctaaagtatc taactcagta ctatttggtt agtcaaccta ataggacaag
    11461 attatgggag cgcggacatt gtttgctatc aagtcgttgt ttgctctagc aatggccatt
    11521 tttggagcta ggtttcttca cgaccttgat cacaacgctg tcatttcagc ggctggcgct
    11581 ctttcgacta tttctggggt tctttttggt ttcgttttgg cttcagtcac tatcctaagt
    11641 agtttcgaca gttcaaaggg aatcattggc gctttaaaaa gcaacggcgt attaaaagga
    11701 attatcgaag gtcttttcgg gacgggcact acactgatag cagcctgtct atcagcaatg
    11761 gtatccatgt ttgcccctgt agttagcaac ttagctttag actattatgc tctattgctc
    11821 gcaggggcgt acttgataat ctcaatggtt agtttttttt ttctttaatt ggcagtctct
    11881 atcaaaaaaa taataggtta tatgtagttt ttataaaatt cgtgcttggg gtcttatttc
    11941 cctataatat aagtgagtta cgaataaact ttctgctatg agtcctctca gcgaccaggg
    12001 atgaattttg aagtcactgt gtttaatggc gtctgtttcc tctctggctg aatatgcaaa
    12061 tcatagtggt ggctttgctg atacgttttc agccaagctg ctatccaaag gcaatgacac
    12121 ccagccagaa ggtagcctgc ccgtccgctg cggcattgca cggcagcgat accgccagcc
    12181 tggccatagc catgctcgta ccttttcccg ttgtccgggt ctcagggtcg gccaccagcc
    12241 gcacgtatgc tgaaatttgt gctgccatgc tcacctctct ctcggccagt ctctgttttt
    12301 tttctgataa taaacagaaa tagtgttggt tcagttggtt cagttggttc actgcccgcc
    12361 agcccgcgcc gttactgggt tttcctgaac caacttcagc aattttgcgt tggttcagcg
    12421 gggcattctg ttggttcacc gcctgccagg gaaaaaactc tacgcgctgg cgttggttca
    12481 aaataggcat ttgttggttc agtgttagtt cagattcata attaaaatgc ttataaaaca
    12541 gtaaccttta attactgaac caactgaacc aactgaacca acacccttta ctcgtatgtg
    12601 agaaatacta ttcctctggc tggttgtagt cctccggcag gtagttgagg acgtaaacgt
    12661 tgatctgcct cccctggata cgtggagact tgcgctgata tccgcgtccg ctgctcggcg
    12721 gcgtcagcat tcccgctctt ttcagtactt cggcaaactg cttgtgatta aagcccgcgg
    12781 cgatttcctt ctcgaacgtt gccgggaacg tatagaacga tatcgggctc tcgtcgtgtt
    12841 ccccctggcg ccgccggtag ccggctagtt cttttattgg caggtcggcc gggctgtaag
    12901 gaaacggcgc aaaccggctc aggccgtagg cgttaagaaa cgcctccgtt tgctcgatga
    12961 tctgctgatg ctctttgttg ccggtgccga actcccgcag ccaggcgtta tagctgtgct
    13021 gtaccgcatc ccggcaggtc tgtgcatccc agccggtgat gccggcgctc agcagcaacg
    13081 ccgcctccag aatagcgaac ctggcggcta cgcgatgtac ctgctcgccg tagtctgcag
    13141 gtatcaggct gcgccagcgg gcctcacacc cccggacagc ttctgtagcc tgctgctggt
    13201 ggtcggccag ccacttaatc cactgccgcc cagcggcgcc gtggtggtgc tggtatgcct
    13261 ccttcagcgc atccgcgtgc tgcttgccgt tctggtgctc gtggaagtga accgccttac
    13321 tcagcgggat attcagcagc cgcaccagct gcccggcttt ggtcctgcgt ccggcgcccg
    13381 cgatgaaggt ttccaaatcc atctcgccgg tgctgattgc cacggtgcgc cagcgcttta
    13441 agtcccggtt gccgcccctt cgcaccctgc agcttcccaa ccccgttaaa agcgcatagg
    13501 cagactgcga cacgcttacc gggtcggatc ccttgccgac ctcatccagc ggcatcaggc
    13561 cgtcattgtg tgcggcggct tcgttcgcca gccccagcgc cgtgccgtac cacgtcaggc
    13621 gcagtaaatc cgggttgcca tacaggctgc tggccacgtt cgccgtggtg gtcttgcccg
    13681 cgctcgactg ctcatagaag tggatcccga agccatcggc gcccgccagg ccaatcagcg
    13741 gcgccgccaa cgctgcggcg gtcgcagtca tcatggagta gttaccggct accaggtgcg
    13801 ccacgctgcc gcgccagtcc tcagcggtgc ctttgacggt gtagccggcc gccgccgagc
    13861 tgcggccgtt gaacagcacc ggatgttccg gcgttccgat aacctcgccg tccggcatga
    13921 tgtatgcccc gcactgccag cccgtcgcgt gggcaacgcg ccacagctcc cgcgcgccgc
    13981 tgcgctgtag ccagtcggcc aggatcgcgc gcaggctgct tttggtggtg acgttaatcc
    14041 cgcccgcctt cagggtgcgc cagccttcac gctcgccaat atcagccagg gggattgcgg
    14101 ccgtcgtcag cgcgctgaca ccgaatgcct gccagcggat aatcaggtac tggtctttat
    14161 catcccggcc ggtgcccacc acttccagcg gcgaacacag ccacgcttcc cggttgataa
    14221 cctcccgctg tccttgtcca ctttcggtgt tacccagaaa acgccgtctg cgcggctctc
    14281 aacatgcggc ttaagcgggt ctttctctgg caggccggac tttccgccct caatggcctg
    14341 taactgcggt ttcacgctgc ccccctgcgg ttgatacatc gaatggttaa aggctgctgt
    14401 agcggctgcc agcccgtgct gctggtggta gtcgttccag tcggccttat agtctgtcgg
    14461 cggcacggac acataaccat ccacggataa ggccgctttc tcggcacgct ctgtgccggt
    14521 gttgggcttg tcgtctaatc tgtcgttatc ggcggcaatg acgatctgcg ccagcgggta
    14581 ctttcggcgc atcacttccg cgactggcag caggttgccc gcgtcaattg ctgccactgc
    14641 cagcgcgtcc gggcgcatca ggtgaactga aagggccgtt gccagcccct cggcaattaa
    14701 aacgctctgc ggcgattctg gcgcgtttac ggcgtgatat gccccgcgct ttgccgaacc
    14761 cgtcagaagt cgcttttctc catgcggtgt aatagtctgc gccgctgcca ctgcgccgga
    14821 ctcgtccacc agctccagca ataacgaacc atcgggcata agcgggtatt taaacccggt
    14881 cagccctttg attgcaggta ctcagattct ccctgtatgg atctcaggcg cattccggta
    14941 tacagacggg caaacgtagc ccttcgatgc tctgcgtcct ctgctgcctg tttctggcgc
    15001 tcctgctcac gctgctggcg gtctgcggct aactgcctct gtctctggct ggcagcgtct
    15061 ggtgctgatt ctgcggcccg gtaatcaata cccagcacat cggcggcaag ttgcgccgcc
    15121 tctgtggtgt cgcagttgtt cacccgtttg attaagtcca gcccgtcgcc agcgccacac
    15181 tggttgcaga taaagctgcc gcgcccgttg tcgtcgaatc tgaaacggtc ttttccacca
    15241 catgcagggc atggggaatg gcggcgcgat gaatcaggca cgtcgataga caatccggcc
    15301 agcacataag gccatcgccc tgctgcggcg ctggtcactt cgcggataag gtcgatatta
    15361 cgcattcgtg ttacctccct cagtgcgccg ctggcatttc aggcaagccg ttttcattca
    15421 gatcggcaat gaatccatcg tgtagctctg ccagcgtctg acgcccgaaa ggggtcaact
    15481 cgccgcgctc cgtgtcgatc atggcctgat aaaaaacaat ggcgttcgct gttccctgct
    15541 caatgccgta gcgctcaatc atcgcgccct ccatgttgtt agccatcgcc agacgttccg
    15601 cgaacgggta aaccacaatc ccctccgtgc catttgaata aaacgtcacc agcgacgatt
    15661 tgccgtcatc ctccttgatg gtggttgtgc cgttttcgcg cttcatctca gaaatgaacg
    15721 tcgcagcaat cagccagcgc cacatagtga cgttatgctg cgcggtgaag tcgaaccagc
    15781 cacgcgcccc gccatcagca acggcaaaat gaatggcgta tccgatatct ggcttgtcgt
    15841 cgtactctcc ggcgtcaagg ccgttcacgg cgctctcgta gctgataaga gcaaactgct
    15901 catatccccc ggcatcattg cgggtcatga tattgacgcc gtgcggtgtg gcttcggcgt
    15961 gtaataagtc ggcatttccc ggtgtgaatt tctctacgtt gctcatgctt tgccgtccag
    16021 actcaaatcc atatcaacta actcgccttc tactgaatcc atcagctcgg ggataccatc
    16081 cagaagggta atgactgcgc caataagatg atccgtgccg ctatcttttt taatcggtgc
    16141 ttcaagccaa atagaaagaa cttgctgcgc ttgcttgata cggcaggctg aatcaatcag
    16201 ggataacttg ctcatgcgct gccctcccga tactcgcgca tcttcgttag ttcatcagct
    16261 aggcgattaa ctttgcgctc ggttctaatg gttgcgcatc tcaattcggt gattaatgtc
    16321 gcaagtctgg caccataaag cggattggcg gcacgtaatg gcccgtccag ataaagattc
    16381 cataactcaa gcaattcact ggcatagcgc accgctgccg ttgcgtcacc tgtcgggatg
    16441 gtttctggtt caattacggc gactgtattc atgctgccac ctcacgaatg cgggtgatct
    16501 ggatgtggga aaggcgttca tttctggcct gatttagcgc ctcaactttg gcgctgatcg
    16561 cgctgcgggc gtcaacgata taaacgaact cgactaattc gccgctccgg gcggtggcgc
    16621 atcctgcaac acggaagtaa ttaagcatgt gcgccccctg tgcgaatacg tccggcgaaa
    16681 aagcagacgt gatcccgaac cagagaacgg cgggcttcgc gctcagaagg cgcggcaata
    16741 tggtgaattt ttgcggtaat tgtcggcata tcgcggcgaa cagcggcgat aatccaaata
    16801 aattgcggat tttgggtgag ggtagtagcc atgcggcagc ctccattcga tagcgggtaa
    16861 cgctaccacc ggaaacgcca atttcactgg tggtagccca agcagggttg gcgtaaccgg
    16921 ctcgaatgga taccggcgct tccgaagaag cccctgcctg agccaccatt gcttttgcga
    16981 ggcgctggat tatatcccaa cgctcaaaaa aagggtgagt cagactaacg gcacaaaaaa
    17041 agacgctagg cgcgtcatgt gtcgccattc gaattaccag gacgccaatc ccggcaccag
    17101 attttgctgg tgcgctataa ccatagaccg ggataccttc agaccgcaag ccctttttgt
    17161 cacggcgcgg caatttatag ctggcggtgt gatgggcccc gcatctaccg ccggcgccgg
    17221 acacgctatc ttccagatag tcagtttccg aacgcttacc cgcgcgctta cttgtctcga
    17281 aatacacttc aacagagcca ctatcaatgg cccacagaat gacaggtttt gacaggttcc
    17341 cacggtggcg caccgcctgc agagcgttaa cttttgcata catcaggcca gccagagaga
    17401 ggcttttgca ccgggcggcg gtaatcattg ctttacctcc gtgtactcct tcatgaagcg
    17461 ctcaatgggc tgtacgcatg ggaactgata gccctggcga tagaacgtca cgcggttatg
    17521 cgctacagcg gtcacgctca ctatctggcc gtgagcgtcg cgataggaat ggtttggcag
    17581 cggcgtgctg gtggtcttaa ccattaatga acctccagca gatctggctg atacttacgc
    17641 catagctcga tttcttcagc agcaaggcgg gccttctcat ctttgcacga ctgcaggtct
    17701 ctaccgcgct tactggcttt cttcgtgcac agctctttgc gccgggtatg gtcattcagg
    17761 aatgcgaacg gcactccgta ggagccggtt ttgcggatgg acgggataac gtcgcggaat
    17821 acccagttgc tgaagcggtg ggcgaacgta ccgggcgtgg aggctttacg gctgcgggca
    17881 atcagtttat agaagccaga ttctgcggcc atattccagc tacgtgcccc gccgcgctta
    17941 cccgaatgac cctcagttaa agttagggtc attacctcgt cacaatccag agaggaaacg
    18001 gcactggttg gattgttgat ttccaacgtc tggcagacgt cagatacaac gaaccacggc
    18061 tcaccgtaaa cattcacaat gcgcacggta tacccctcaa atttaataac tgaaatatcg
    18121 ctctcttcgg cttggaatat ctctttctgg ctggctacag gctgaggggc aggcattgag
    18181 actacctcgg ctttggtaac tgaatgctta gtcatgagcc acccccagac gctttgccag
    18241 ccaccgctga gacaggcgga ttagctctgc tttacgctgg ccgtactcca tccccatatc
    18301 gatcagcgtg atgttggtgc tctctaggta gctgaggtgc tccagttggc cggcactcat
    18361 gctatcgcgc ggttcgcggt cgataccgtt cacttgcgcc cactgcttcg ccgtcatgcc
    18421 acccagcacg atacgggcga tcatgttgct ttcattgctg tagtggcgag ccagcgtctg
    18481 tttaccctgt tctgcgcggg cgctttccag cgctacgcac atcggtttaa acaggttggc
    18541 ggcactgata cgggctttag ctggcggcga tacagagcgg caatctctgg cacgctgcgc
    18601 tgtagtgctt cctcacactg aatgaagtaa cgtcgaacgg cgcggccctg ctcgttgcgt
    18661 tcaaccattg ccacttcttt agccatatcc agcgagaagg taatcatgct cgatttgctg
    18721 gcgaaatttt gcgctcgccc gttttggcgt gctcaaattt tcaacacgga taaaatcggt
    18781 tccggcaatg aaaccgtact ggtcaattcg gcctttaatc cagttagtaa agtcgcggcc
    18841 caccccagcg ccttatgcaa ggctctggcg ctcgcaatat tggcttcacg cccgccaatg
    18901 cgtccggcaa taacgggaac aatagcggca aagtcgttgc cgttaattac tcccgtgtta
    18961 acgttgggtt gcggggcggc ccccgaactg aatcggcttt tttcgatagt catattttcg
    19021 gctccgttat gcggcggtga gattgtacgg gtatagattg agaatgtccg cgatatcctg
    19081 cttagaaagc ccgttatagc caccagcggt ggcgttgtgg ttcacaagcc gaataacttt
    19141 tagaacgtca ccgcgcccgg taaagcgata gcgtaaatgt gacccgatcc cgtcgggatt
    19201 cttttcgtca atacgctcaa tctgaatat
//
