LOCUS       CP030697               30991 bp    DNA     circular BCT 10-OCT-2019
DEFINITION  Staphylococcus aureus strain ER01532.3 plasmid unnamed2, complete
            sequence.
ACCESSION   CP030697
VERSION     CP030697.1
DBLINK      BioProject: PRJNA470993
            BioSample: SAMN09483952
KEYWORDS    .
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 30991)
  AUTHORS   Sullivan,M.J., Altman,D.R., Chacko,K., Cliferri,B., Webster,E.,
            Deikus,G., Lewis,M., Khan,Z., Beckford,C., Rendo,A., Samaroo,F.,
            Sebra,R., Karam-Howlin,R., Southwick,K., Adams,E., Ying,L.,
            Kornblum,J., Factor,S., Danesh Yazdi,M., Dingle,T., Hamula,C.,
            Bashir,A., Schadt,E., Kasarskis,A., Patel,G., Wallach,F., Gibbs,K.
            and van Bakel,H.
  TITLE     Whole genome sequencing to identify and define MRSA outbreaks
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 30991)
  AUTHORS   Sullivan,M.J., Altman,D.R., Chacko,K., Cliferri,B., Webster,E.,
            Deikus,G., Lewis,M., Khan,Z., Beckford,C., Rendo,A., Samaroo,F.,
            Sebra,R., Karam-Howlin,R., Southwick,K., Adams,E., Ying,L.,
            Kornblum,J., Factor,S., Danesh Yazdi,M., Dingle,T., Hamula,C.,
            Bashir,A., Schadt,E., Kasarskis,A., Patel,G., Wallach,F., Gibbs,K.
            and van Bakel,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUN-2018) Genetics and Genomic Sciences, Icahn School
            of Medicine, One Gustave L. Levy Place Box 1498, New York, NY 10029,
            USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.2.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 236.365311325x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 07/02/2018 08:40:28
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            Annotation Method :: Best-placed reference protein set; GeneMarkS+
            Annotation Software revision      :: 4.5
            Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region
            Genes (total)                     :: 3,104
            CDS (total)                       :: 3,022
            Genes (coding)                    :: 2,934
            CDS (coding)                      :: 2,934
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 44 of 88
            Pseudo Genes (incomplete)         :: 40 of 88
            Pseudo Genes (internal stop)      :: 24 of 88
            Pseudo Genes (multiple problems)  :: 19 of 88
            ##Genome-Annotation-Data-END##
            Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..30991
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="ER01532.3"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="unnamed2"
                     /geo_loc_name="USA:New York City"
                     /lat_lon="40.7903114 N 73.9528738 W"
                     /collection_date="2015"
                     /collected_by="Mount Sinai Hospital"
     gene            join(30616..30991,1..2)
                     /locus_tag="DQU71_15325"
                     /pseudo=""
     CDS             join(30616..30991,1..2)
                     /locus_tag="DQU71_15325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866106.1"
                     /note="incomplete; partial on complete genome; missing
                     start; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding response regulator"
                     /name="DNA-binding response regulator"
     gene            join(30990..30991,1..880)
                     /gene="nsaS"
                     /locus_tag="DQU71_15330"
                     /pseudo=""
     CDS             join(30990..30991,1..880)
                     /gene="nsaS"
                     /locus_tag="DQU71_15330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012656189.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /name="nsaS"
     gene            1005..1925
                     /locus_tag="DQU71_15335"
     CDS             1005..1925
                     /locus_tag="DQU71_15335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="QFM23095.1"
                     /translation="MNNIIEINNLTKQYGSQIAVNNLSITVESGQIYGFLGRNGAGKTT
                     TIRMLLGLIKPTKGNIKIFEKEFESNKTEILKNIGAMVETPGFYSNLTAKENLTINAKI
                     LGIQKENAIEEVLEIVGLASEKVKLFKNYSLGMKQRLGIARALLHNPELLILDEPTNGL
                     DPIGIKEIRKLIKDLAQSRNITILISSHILSEIEQLVDKVGIIHNGVLLEEIMYEDLKK
                     KNRQFISISVSDEEKVACLLETNFGIYDYKIKENGEFKIYSHIDRQQEINRLLVLNNID
                     VFQMRVIEDNLETYFEDLVGGGTIG"
                     /name="ABC transporter ATP-binding protein"
     gene            1918..2655
                     /locus_tag="DQU71_15340"
     CDS             1918..2655
                     /locus_tag="DQU71_15340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000369394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="QFM23096.1"
                     /translation="MDNLLRTEFIKLKRSYMFLISILGTCVAPFMVVVASFISMRTKVP
                     TPNIVFKQLFEEVSLYHMLIIGPPLYGVIIAYLFGREYIEDTLKNLLIIPISRESFLVS
                     KIILLFLWIQTLSVIAWLLTLMLGMLLHFQGLSQSLIIDSFFTFVIGGVLLWILSPPII
                     ILSIYFKNYVPTIVLTIIITLINLMTANSEHRGLFPWAAVGDISRGTLPNTYPFLLSLI
                     IIIVTSIFSVIILFSYFKKTDIS"
                     /name="ABC transporter permease"
     gene            2669..2872
                     /locus_tag="DQU71_15345"
     CDS             2669..2872
                     /locus_tag="DQU71_15345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001627151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP kinase"
                     /protein_id="QFM23097.1"
                     /translation="MGFIEQIKAFILGVVEGLTEFAPVSSTGHMIIVDDMWLNTADDLG
                     SASATTFKVVIQLGGSVAKLNL"
                     /name="UDP kinase"
     gene            2902..3576
                     /locus_tag="DQU71_15350"
     CDS             2902..3576
                     /locus_tag="DQU71_15350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="QFM23098.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            3717..4352
                     /locus_tag="DQU71_15355"
                     /pseudo=""
     CDS             3717..4352
                     /locus_tag="DQU71_15355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="internal stop; incomplete; partial on complete
                     genome; missing start; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside adenylyltransferase"
                     /name="aminoglycoside adenylyltransferase"
     gene            4349..4879
                     /gene="sat4"
                     /locus_tag="DQU71_15360"
     ARG             4350..4876
                     /name="sat4"
                     /gene="sat4"
                     /gene_name="streptothricin N-acetyltransferase Sat4"
                     /tool="amrfinderplus"
                     /drug_class="STREPTOTHRICIN"
                     /identity="97.78"
                     /coverage="100.0"
     gene            4972..5766
                     /gene="aph(3')-IIIa"
                     /locus_tag="DQU71_15365"
     ARG             4973..5763
                     /name="aph(3')-IIIa"
                     /gene="aph(3')-IIIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(5874..6062)
                     /locus_tag="DQU71_15370"
                     /pseudo=""
     CDS             complement(5874..6062)
                     /locus_tag="DQU71_15370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913594.1"
                     /note="incomplete; partial on complete genome; missing
                     start; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            6042..6500
                     /locus_tag="DQU71_15375"
                     /pseudo=""
     CDS             6042..6500
                     /locus_tag="DQU71_15375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_003446809.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /name="transcriptional regulator"
     gene            6398..6613
                     /locus_tag="DQU71_15380"
     CDS             6398..6613
                     /locus_tag="DQU71_15380"
                     /inference="COORDINATES: protein motif:HMM:PF13280.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="QFM23101.1"
                     /translation="MENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPASGGQ
                     EPESRMIEPISLGFYEQNWYLIGFAG"
                     /name="WYL domain-containing protein"
     gene            complement(6782..7456)
                     /locus_tag="DQU71_15385"
     CDS             complement(6782..7456)
                     /locus_tag="DQU71_15385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="QFM23102.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(7481..8314)
                     /locus_tag="DQU71_15390"
     CDS             complement(7481..8314)
                     /locus_tag="DQU71_15390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002455975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="QFM23103.1"
                     /translation="MQYNTTRSITENQDNKTLKDMTKSGKQRPWREKKIDNVSYADILE
                     ILKIKKAFNVKQCGNILEFKPTDEGYLKLHKTWFCKSKLCPVCNWRRAMKNSYQAQKVI
                     EKVIKEKPKARWLFLTLSTKNAIDGDTLEQSLKHLTKAFDRLSRYKKVKQNLVGFMRST
                     EVTVNKNDGSYNQHMHVLLCVENAYFRKKENYITQEEWVNLWQRALQVDYRPVANVKAI
                     KPNRKGDKDIESAIKETSKYSVKSSDFLTDDDEKNQEIVSDLEKGWFCCKVEFIV"
                     /name="protein rep"
     gene            8766..9347
                     /locus_tag="DQU71_15395"
     CDS             8766..9347
                     /locus_tag="DQU71_15395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QFM23104.1"
                     /translation="MNAIQNSISLRKILVVSLSILTILSMVLDFNFKEAQAQNKNNIAD
                     KNVETLNEKEIEKELKYIYGKIIILDKDGTAKDVNLENAKSRYGYVPEGFQKLKNDIEN
                     KKKTSSISPRAVGGNYKNSGDCFYSEVLNSYGELLTGNIITAVFEDVKAKNLKGVAKKL
                     AKIGIKGNLAGIAATMVSKDVQCNLKYGLL"
                     /name="hypothetical protein"
     gene            complement(9673..9861)
                     /locus_tag="DQU71_15400"
     CDS             complement(9673..9861)
                     /locus_tag="DQU71_15400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QFM23105.1"
                     /translation="MNKNTVLDEGYVIATILNVFFLLGLIFISHLENLYILIPYVILMG
                     INAIYLVVKVMNFKKNN"
                     /name="hypothetical protein"
     gene            10246..10437
                     /locus_tag="DQU71_15405"
     CDS             10246..10437
                     /locus_tag="DQU71_15405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001791934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QFM23106.1"
                     /translation="MIGLAKPEIPGVLRYFKVISYKAVLSYFCDTIYCVCLIFVTLHTA
                     FVTKIRQYFFIKNQQKRH"
                     /name="hypothetical protein"
     gene            complement(10444..10644)
                     /locus_tag="DQU71_15410"
                     /pseudo=""
     CDS             complement(10444..10644)
                     /locus_tag="DQU71_15410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820328.1"
                     /note="incomplete; partial on complete genome; missing
                     start; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /name="replication protein"
     gene            complement(10705..11379)
                     /locus_tag="DQU71_15415"
     CDS             complement(10705..11379)
                     /locus_tag="DQU71_15415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="QFM23107.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(12049..12627)
                     /locus_tag="DQU71_15420"
     CDS             complement(12049..12627)
                     /locus_tag="DQU71_15420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="QFM23108.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEAKENKNK"
                     /name="HTH domain-containing protein"
     gene            complement(12891..13271)
                     /gene="blaI"
                     /locus_tag="DQU71_15425"
     ARG             complement(12895..13271)
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="98.41"
                     /coverage="100.0"
     gene            complement(13261..15018)
                     /locus_tag="DQU71_15430"
     CDS             complement(13261..15018)
                     /locus_tag="DQU71_15430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactam sensor/signal transducer BlaR1"
                     /protein_id="QFM23110.1"
                     /translation="MAKLLIMSVVSFCFIFLLLVFFRYILKRYFNYSLNYKVWYLTMLA
                     GLIPFIPIKFSFIKFNNVNNQAPTVESKSHDLNHNINTTKPIQEFTTDIHKFNWDSIDN
                     ICTVIWIVLVIILSFKFLKALLYLKYLKKQSLYLNENEKNKIDTILFNHQYKKNIVIRK
                     AEAIQSPITFWYGKYIILIPSSYFKSVIDKRLKYIILHEYAHAKNRDTLHLIIFNIFSI
                     IMSYNPLVHIVKRKIIHDNEVEADRFVLNNINKNEFKTYAESIMDSVLKTPFSNKNILS
                     HSFNGKKSLLKSRLINIKEADLKKQSKLILIFICIFTFFIMIIQSQFLMGQSLTDYNYK
                     KPLQSDYQILDESKNFGSNSGSFVMYSMKKDKYYIYNEKESRKRYSPDSTYKIYLALFG
                     LDRHIISDKNSRMSWNHKHYLFESWNKEQDLNTAMQNSVNWYFERISNQIPKNYTAAQL
                     KQLNYGNENLGSYKSYWMEDSLKISNLEQVIVFKNMMEQNNHFSKKAKNQLSSSLLIKK
                     NEKYELYGKTGTGIVNGKYNNGWFVGYVITNHDKYYFATHLSDGNPSGKNAELISEKIL
                     KGMGVLNDQ"
                     /name="beta-lactam sensor/signal transducer BlaR1"
     gene            15125..15970
                     /locus_tag="DQU71_15435"
     CDS             15125..15970
                     /locus_tag="DQU71_15435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /protein_id="QFM23111.1"
                     /translation="MKKLIFLIVIALVLSACNSNSSHAKELNDLEKKYNAHIGVYALNT
                     KSGKEVKFNSDKRFAYASTSKAINSAILLEQVPYNKLNKKVHINKDDIVAYSPILEKYV
                     GKDITLKELIEASMTYSDNTANNKIIKEIGGIKKVKQRLKELGDKVTNPVRYEIELNYY
                     SPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKNFLLDLMFNNKNGDTLIKDGVPKDYKV
                     ADKSGQAITYASRNDVAFVYPKGQSEPIVLVIFTNKDNKSDKPNDKLISETAKSVMKEF
                     "
                     /name="penicillin-hydrolyzing class A beta-lactamase BlaZ"
     gene            16179..16274
                     /locus_tag="DQU71_15440"
                     /pseudo=""
     CDS             16179..16274
                     /locus_tag="DQU71_15440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001560862.1"
                     /note="incomplete; partial on complete genome; missing
                     stop; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase domain-containing protein"
                     /name="O-antigen ligase domain-containing protein"
     gene            complement(16496..16915)
                     /locus_tag="DQU71_15445"
     CDS             complement(16496..16915)
                     /locus_tag="DQU71_15445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="QFM23112.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            17039..18010
                     /locus_tag="DQU71_15450"
     CDS             17039..18010
                     /locus_tag="DQU71_15450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH:quinone reductase"
                     /protein_id="QFM23113.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFEEFYKTIDQLLKGQHLGRTILKV"
                     /name="NADPH:quinone reductase"
     gene            complement(18182..18274)
                     /locus_tag="DQU71_15455"
     CDS             complement(18182..18274)
                     /locus_tag="DQU71_15455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="QFM23114.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(18431..18778)
                     /locus_tag="DQU71_15460"
     CDS             complement(18431..18778)
                     /locus_tag="DQU71_15460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="QFM23115.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="transcriptional regulator"
     gene            complement(18797..19414)
                     /locus_tag="DQU71_15465"
     CDS             complement(18797..19414)
                     /locus_tag="DQU71_15465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017465246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium transporter"
                     /protein_id="QFM23116.1"
                     /translation="MIQTVVAAAVLYIATAVDLLVILLIFFARAKTRKEYRDIYVGQYL
                     GSIILILVSLFLAFVLNYVPEKWILGLLGLIPIYLGIKVAIYDDCEGEKRAKKELNEKG
                     LSKLVGTVAIVTIASCGADNIGLFVPYFVTLSVTNLLLTLFVFLILIFFLVFTAQKLAN
                     IPGIGEIVEKFSRWIMAIIYIALGLFIIIENDTIQTILGFIF"
                     /name="cadmium transporter"
     gene            complement(20530..20724)
                     /locus_tag="DQU71_15470"
     CDS             complement(20530..20724)
                     /locus_tag="DQU71_15470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QFM23117.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     gene            20834..21526
                     /locus_tag="DQU71_15475"
     CDS             20834..21526
                     /locus_tag="DQU71_15475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QFM23118.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVE
                     YKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTA
                     FAAGCSVG"
                     /name="hypothetical protein"
     gene            complement(22390..22706)
                     /locus_tag="DQU71_15480"
                     /pseudo=""
     CDS             complement(22390..22706)
                     /locus_tag="DQU71_15480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002483623.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /name="replication protein"
     gene            complement(22699..23682)
                     /locus_tag="DQU71_15485"
     CDS             complement(22699..23682)
                     /locus_tag="DQU71_15485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="QFM23119.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNK
                     PNILYLMKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSKIERPEVRK
                     SNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNQFTHNFDDKEMLLQEFPE
                     QLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHD
                     RGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication protein"
     gene            24108..24851
                     /locus_tag="DQU71_15490"
     CDS             24108..24851
                     /locus_tag="DQU71_15490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002508633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="QFM23120.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     gene            complement(25078..25263)
                     /locus_tag="DQU71_15495"
     CDS             complement(25078..25263)
                     /locus_tag="DQU71_15495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011276570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="QFM23121.1"
                     /translation="MKNRIREYRKQKGISQETLSKELKVSRQTINAIENNKYDPTLTLA
                     FKLARLFDTTVDELFS"
                     /name="transcriptional regulator"
     gene            complement(25268..25606)
                     /locus_tag="DQU71_15500"
     CDS             complement(25268..25606)
                     /locus_tag="DQU71_15500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QFM23122.1"
                     /translation="MNLIPFIIILIFSCLWTAITNKYLPSETLDKKGQQDRYDERQRKM
                     FIEILAKSFIWIVYCMLFTLVLKFTGLSPSIEGSWFSQYPEIFFIIVALFLMLFNYYTT
                     NKKYTSKG"
                     /name="hypothetical protein"
     gene            complement(25852..26460)
                     /locus_tag="DQU71_15505"
     CDS             complement(25852..26460)
                     /locus_tag="DQU71_15505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="QFM23123.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEIIETVNYLKEKDVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRV
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDKGLS"
                     /name="recombinase family protein"
     gene            complement(26946..27845)
                     /gene="mph(C)"
                     /locus_tag="DQU71_15510"
     ARG             complement(26950..27845)
                     /name="mph(C)"
                     /gene="mph(C)"
                     /gene_name="Mph(C) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(27944..29410)
                     /locus_tag="DQU71_15515"
     CDS             complement(27944..29410)
                     /locus_tag="DQU71_15515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002447408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(A)"
                     /protein_id="QFM23125.1"
                     /translation="MEQYTIKFNQINHKLTDLRSLNIGHLYAYQFEKIALIGGNGTGKT
                     TLLNMIAQKTKPESGTVETVGEIQYFEQLNMDVENDFNTLDGSLMSELHIPMHTTDSMS
                     GGEKAKYKLANVISNYSPILLLDEPTNHLDKIGKDYLKNILKYYYGTLIIVSHDRALID
                     QIADTIWDIQEDGTIRVFKGNYTQYQNQYEQEQLEQQRQYEQYISEKQRLSQASKAKRN
                     QAQQMAQASSKQKNKSIAPDRLSASKQKGTVEKAAQKQAKHIEKRMEHLEEVEKPQSYH
                     EFNFPQNKIYDIHNNYPIIAQNLTLVKGSQKLLTQVRFQIPYGKNIALVGANGVGKTTL
                     LEAIYHQIEGIDCSPKVQMAYYRQLAYEDMRDVSLLQYLMDETDSSESFSRAILNNLGL
                     NEALDRSCNVLSGGERTKLSLAVLFSTKANMLILDEPTNFLDIKTLEALEMFMNKYPGI
                     ILFTSHDTRFVKHVSDKKWELTGQSLHDIT"
                     /name="ABC-F type ribosomal protection protein Msr(A)"
     gene            29884..30558
                     /locus_tag="DQU71_15520"
     CDS             29884..30558
                     /locus_tag="DQU71_15520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001106057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="QFM23126.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     ARG             complement(27948..29410)
                     /name="msr(A)"
                     /gene="msr(A)"
                     /gene_name="ABC-F type ribosomal protection protein Msr(A)"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(13265..15018)
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.38"
                     /coverage="100.0"
     ARG             15126..15967
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(18801..19414)
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(27945..29410)
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="98.36"
                     /coverage="100.0"
     ARG             complement(26947..27845)
                     /name="mphC"
                     /gene="mphC"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="98.66"
                     /coverage="100.0"
     ARG             4362..4879
                     /name="SAT-4"
                     /gene="SAT-4"
                     /gene_name="streptothricin acetyltransferase (SAT)"
                     /tool="rgi"
                     /drug_class="nucleoside antibiotic"
                     /identity="97.16"
                     /coverage="95.56"
     ARG             3754..4055
                     /name="aad(6)"
                     /gene="aad(6)"
                     /gene_name="ANT(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="99.0"
                     /coverage="36.23"
     ARG             15126..15970
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     Typing          complement(10210..10374)
                     /name="MOB_unknown"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="2.42e-81"
     Typing          complement(22187..22334)
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          complement(7511..8314)
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.752"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(10447..10623)
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.258"
                     /coverage="94.0"
                     /evalue="6.2e-68"
     Typing          complement(22393..22568)
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="92.697"
                     /coverage="94.0"
                     /evalue="1.04e-65"
     Typing          complement(22700..23682)
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.593"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          24109..24851
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 gaatttcttg aaatcaatcc aacgtgaaat ttatattgtc atccttactt gtgctttatt
       61 ctactttata ttattcatgt ataatgtgcc gatgcaagca tatatgattg gtctaggtat
      121 tgtattgttt gtttcaatga tttactgggg tatccattac atgaacttta aaaaagaata
      181 aacactacag gaacagaacg aagatttaag aatcgaaaac cataaacttc gtaatgactt
      241 tattaactac caaagtgagt tagagtcata ttttttaatg tgggtgcatc aaatcaagac
      301 accgattaca gcatcaaagt tactgcttga agatcctgat gaacacgtga tttctaacgt
      361 gcgtaatgaa gtcttacaaa ttgataatta cacgaatctt gcactgaact atttgaaact
      421 catgaaccaa aagacataca tggtctttat ggaagtgagt gtagatgaat taattcgacc
      481 actgattaaa cgttatgcga tacagtttat tcatcatcaa acaaagttgc attatgagaa
      541 aagtgaagcg gttatattaa cagatgccaa atgggcatca attatgattg agcaaatatt
      601 aaacaatgca ttaaaatatg cacgtggcaa agatgtgtgg attacgtttg acgaaaatac
      661 aaagaaatta tcaatccgag ataacggtat cggcattaat gcgagtgatt taccgaaaat
      721 ctttgataaa ggtttctcgg gctataacgg tagaataagt gagaaatcaa gcggtattgg
      781 tttatatatt gtcagcacaa tctcaaagcg cttaggccat aaagtaagtg ctacatctac
      841 attaaacgat ggttcaatat tcaccattca atttaaataa ctccaatctt tcatttttgt
      901 aagattagcg gctgtttttg taagaataga taaaggcagc cttttctaat cgcgcgtaag
      961 ataaaggtaa caacaaacta agaaaggtgc cagaggtgaa aaatttgaat aatataattg
     1021 aaataaataa cttaacaaag caatatggaa gtcagatagc agttaataat ttgagtataa
     1081 ctgttgaaag tggacaaatt tatggttttt taggaagaaa tggtgcaggc aaaacaacta
     1141 ctataagaat gcttttaggc ttaattaaac ctacgaaagg taatattaaa atatttgaaa
     1201 aagagttcga aagtaataaa actgaaattt taaaaaatat tggtgctatg gttgaaacgc
     1261 caggttttta tagtaatttg acagctaaag agaacttaac tataaatgct aaaatattag
     1321 gtatacaaaa agaaaatgca attgaagaag tgttagaaat agtaggacta gcttctgaaa
     1381 aagtaaaatt gtttaaaaat tattctttag gtatgaagca acgtttaggg attgcgagag
     1441 ctttattgca caatcccgaa ttattgatac ttgatgagcc gacgaatgga ttagatccta
     1501 ttggcataaa agaaattaga aagttgatta aggatctggc tcaatctaga aatataacca
     1561 ttttaatttc aagtcatata ttgtcagaaa tagagcagtt agtagacaag gtgggtatta
     1621 ttcataacgg agttttgtta gaagaaatta tgtatgaaga tttaaaaaaa aagaacagac
     1681 aatttataag tatatcagta tcagatgaag aaaaagttgc atgtttgttg gaaactaact
     1741 tcggaattta tgactataaa attaaagaaa atggcgaatt taaaatttat tcacatattg
     1801 atagacaaca agaaattaat agattattag tattaaacaa tattgatgtt ttccagatga
     1861 gagtgataga agataatcta gaaacttatt tcgaagactt agtaggaggt ggcacaattg
     1921 gataatctac tccgtacaga atttattaag ttaaaaagat catatatgtt tctaataagt
     1981 attttaggta catgcgtagc accttttatg gtggttgtag cttcttttat tagtatgcgg
     2041 acgaaagtac cgactcctaa tattgtattt aaacagttat ttgaagaagt cagtttatat
     2101 catatgctaa ttattggacc tcctctatat ggggttataa tagcctattt gtttggaaga
     2161 gaatatatag aagatacttt aaaaaactta ttaattatac ctatatctag agaaagtttt
     2221 ttagtaagta aaataatatt attattcttg tggattcaaa cactatctgt tattgcatgg
     2281 ttgctaactt taatgctagg tatgctattg cattttcaag ggttaagcca gagtttaata
     2341 attgattcat tctttacatt tgttattggc ggagtgttat tatggatatt atctccacca
     2401 ataattattt tgtcgatata ttttaaaaat tatgttccca caattgtttt aaccataata
     2461 attactttga taaatttaat gactgctaat tctgaacata gaggattatt tccttgggct
     2521 gcagttggag acatatctag aggaacatta cctaatactt atccatttct attatcttta
     2581 attatcataa ttgttacatc tatattcagt gtaattatat tattctcata ctttaaaaaa
     2641 actgatataa gttaaaagga ggagaaaaat gggttttata gagcagatta aagcatttat
     2701 tttaggtgta gttgaagggt tgacagaatt tgctccagta tcatcaacag gtcatatgat
     2761 tattgttgat gatatgtggt taaacactgc tgacgattta ggaagtgcgt ctgcaactac
     2821 ttttaaggtg gtaatacagt taggaggttc tgttgcaaag ttgaatttat aatataattt
     2881 taacaaaaag gagtcttctg tatgaactat ttcagatata aacaatttaa caaggatgtt
     2941 atcactgtag ccgttggcta ctatctaaga tatgcattga gctatcgtga tatatctgaa
     3001 atattaagag aacgtggtgt aaacgttcat cattcaacga tctaccgttg ggttcaagaa
     3061 tatgccccaa ttttatatca aatttggaag aaaaagcata aaaaagctta ttacaaatgg
     3121 cgtattgatg agacgtatat caaaataaaa ggaaaatgga gctatttata tcgtgccatt
     3181 gatacagagg gacatacatt agatatttgg ttgcgtaagc aacgagataa tcattcagca
     3241 tatgcgttta tcaaacgtct cattaaacaa tttggtaaac ctcaaaaggt aattacagat
     3301 caggcacctt caacgaaggt agcaatggtt aaagtaatta aagcttttaa acttaaacct
     3361 gactgccatt gtacatcgaa atatctgaat aacctcattg agcaagatca ccgtcatatt
     3421 aaagtaagaa agacaaggta tcaaagtatc aatacagcaa agaatacttt aaaaggtatt
     3481 gagtgtattt acgctctata taaaaagaac cgcaggtctc ttcagatcta cggattttcg
     3541 ccatgccacg aaattagcat catgctagca agttaaacga acactgacat gatatattag
     3601 tgattagcta tattttttac tttgcaacag aaccatcatt tttattaaaa tactcttttg
     3661 taaaatcttt ctgctcttca atgtatttaa tttctttacc tctaaatcta ttatagctat
     3721 ttgatgatta caataaaatt gatcttacct tattgccctt ggaagagtta gataattacc
     3781 taaagggcga taaattaata aaggttctaa ttgataaaga ttgtagaatt aaaagggaca
     3841 tagttccgac tgatatagat tatcatgtaa gaaagccaag cgcaagggag tatgatgatt
     3901 gctgcaatga attttggaat gtaacacctt atgttattaa aggattgtgc cgtaaggaaa
     3961 ttttatttgc tattgatcat tttaatcaga ttgttcgcca tgagctgctg agaatgatat
     4021 catggaaggt cggcatcgaa acaggcttta aatgaagtgt aggcaagaac tataagttta
     4081 ttgaaaggta tatatccgag gatttgtggg agaaactttt gtccacctac cggatggatt
     4141 cctatgaaaa catatgggaa gcattatttc tatgccatca attgttcagg gcggtatccg
     4201 gtgaggtggc ggaaaggctt cattatgcct atccggagta tgataggaat ataacaaaat
     4261 ataccaggga catgtataaa aaatacactg gtaaaaccgg ctgcctggat agcacatatg
     4321 ccgctgatat agaagagagg cgggaacagt gattacagaa atgaaagcag ggcacctgaa
     4381 agatatcgat aaacccagcg aaccatttga ggtgataggt aagattatac cgaggtatga
     4441 aaacgagaat tggaccttta cagaattact ctatgaagcg ccatatttaa aaagctacca
     4501 agacgaagag gatgaagagg atgaggaggc agattgcctt gaatatattg acaatactga
     4561 taagataata tatctttact accaagacga taaatgcgtc ggaaaagtta aactgcgaaa
     4621 aaattggaac cggtacgctt atatagaaga tatcgccgta tgtaaggatt tcagggggca
     4681 aggcataggc agcgcgctta tcaatatatc tatagaatgg gcaaagcata aaaacttgca
     4741 tggactaatg cttgaaaccc aggacaataa ccttatagct tgtaaattct atcataattg
     4801 tggtttcaaa atcggctccg tcgatactat gttatacgcc aactttgaaa aagctgtttt
     4861 ctggtattta aggttttaga atgcaaggaa cagtgaattg gagttcgtct tgttataatt
     4921 agcttcttgg ggtatcttta aatactgtag aaaagaggaa ggaaataata aatggctaaa
     4981 atgagaatat caccggaatt gaaaaaactg atcgaaaaat accgctgcgt aaaagatacg
     5041 gaaggaatgt ctcctgctaa ggtatataag ctggtgggag aaaatgaaaa cctatattta
     5101 aaaatgacgg acagccggta taaagggacc acctatgatg tggaacggga aaaggacatg
     5161 atgctatggc tggaaggaaa gctgcctgtt ccaaaggtcc tgcactttga acggcatgat
     5221 ggctggagca atctgctcat gagtgaggcc gatggcgtcc tttgctcgga agagtatgaa
     5281 gatgaacaaa gccctgaaaa gattatcgag ctgtatgcgg agtgcatcag gctctttcac
     5341 tccatcgaca tatcggattg tccctatacg aatagcttag acagccgctt agccgaattg
     5401 gattacttac tgaataacga tctggccgat gtggattgcg aaaactggga agaagacact
     5461 ccatttaaag atccgcgcga gctgtatgat tttttaaaga cggaaaagcc cgaagaggaa
     5521 cttgtctttt cccacggcga cctgggagac agcaacatct ttgtgaaaga tggcaaagta
     5581 agtggcttta ttgatcttgg gagaagcggc agggcggaca agtggtatga cattgccttc
     5641 tgcgtccggt cgatcaggga ggatatcggg gaagaacagt atgtcgagct attttttgac
     5701 ttactgggga tcaagcctga ttgggagaaa ataaaatatt atattttact ggatgaattg
     5761 ttttagtacc tagatttaga tgtctaaaaa gctttaacta caagcttttt agacatctaa
     5821 tcttttctga agtacatccg caactgtcca tactctgatg ttttatatct tttctaaaag
     5881 ttcgctagat agagttctat attagagatg taaagagttt tggtgaagag gtttgtgagt
     5941 atggctttta taaccagggt gcaatgagaa gcactaacag cagctagctt aagaacgcat
     6001 aggatatact ttttatggaa gtcacagagg aggaataaaa tttgaacagg attaacagag
     6061 taacctctat tcttattcag ctgcaatcaa aaaaataatt cctgccaaag aaattgcaca
     6121 gcgatttaat ataagcttaa ggacagttta cagagatatc cggacacttg aagaagccgg
     6181 aataccaatt ggatctgagg ccggaaaagg atattttctt gtagagggct tcctacttct
     6241 gccggtaatg tttacagcgg cggaagtggg tgcattgatt acagcaggga aatttttaaa
     6301 ttgccatgga gatgaatcat ttataaagga ttttgattca gctatgtata aaatcaaatc
     6361 tattttgaag catggtgaaa aaaactatgc acaggagttg gagaacagta ttaacgtgta
     6421 cagcacatct ggacagaaaa atacattggc ggataacgtt attgcagcaa ttcagactgc
     6481 aatctgcaat aaaagggtaa tatcaattca atatcctgca tcaggagggc aagaaccgga
     6541 aagcagaatg atagagccta tatcactggg gttttatgaa cagaactggt acttaatcgg
     6601 ttttgcaggc taagaaatga atataggaat tttcgtgtgg atcggattaa aagcatttgc
     6661 atagaagaag agctctgtca aagccatgat ggctctttgg aacaaatatt aaaacaaatg
     6721 ctggttctgt tgcaaagtaa aaaaatatag ctaaccacta atttatcatg tcagtgttcg
     6781 cttaacttgc tagcatgatg ctaatttcgt ggcatggcga aaatccgtag atctgaagag
     6841 acctgcggtt ctttttatat agagcgtaaa tacactcaat accttttaaa gtattctttg
     6901 ctgtattgat actttgatac cttgtctttc ttactttaat atgacggtga tcttgctcaa
     6961 tgaggttatt cagatatttc gatgtacaat ggcagtcagg tttaagttta aaagctttaa
     7021 ttactttaac cattgctacc ttcgttgaag gtgcctgatc tgtaattacc ttttgaggtt
     7081 taccaaattg tttaatgaga cgtttgataa acgcatatgc tgaatgatta tctcgttgct
     7141 tacgcaacca aatatctaat gtatgtccct ctgcatcaat ggcacgatat aaatagctcc
     7201 attttccttt tattttgatg tacgtctcat caatacgcca tttgtaataa gcttttttat
     7261 gctttttctt ccaaatttga tataaaattg gggcatattc ttgaacccaa cggtagaccg
     7321 ttgaatgatg aacgtttaca ccacgttccc ttaatatttc agatatatca cgataactca
     7381 atgcatatct tagatagtag ccaacagcta cagtgataac atccttgtta aattgtttat
     7441 atctgaaata gttcatacag aagactcctt tttgttaaaa ttatactata aattcaactt
     7501 tgcaacagaa ccaacctttt tctaaatcac ttacaatttc ttgatttttt tcatcatcat
     7561 cagttaaaaa atcagatgat ttaaccgaat attttgaggt ctctttgatt gccgattcaa
     7621 tgtctttatc gccttttcta ttcggtttga tcgctttaac attagcaaca ggtcgatagt
     7681 caacttgtaa tgctctttgc cataaattaa cccattcttc ttgagttata taattctctt
     7741 tttttctaaa atatgcattt tcaacacata acaaaacatg catgtgctga ttataactac
     7801 cgtcattttt attaacggta acttctgttg aacgcataaa tccaacaaga ttttgtttaa
     7861 cctttttata tctactcaac ctatcaaatg ctttagttag atgcttcaaa ctttgttcta
     7921 aagtatctcc atctatcgca ttttttgttg aaagtgttaa aaacaaccaa cgtgcttttg
     7981 gcttttcctt aattactttt tcaatcactt tttgagcttg ataactattt ttcatagcac
     8041 gtctccaatt acaaaccgga cataattttg atttacaaaa ccatgtctta tgtaacttca
     8101 aatagccttc atcagttggc ttaaattcta aaatattacc acattgtttt acattaaaag
     8161 cctttttgat ttttaaaatt tctagtatat ctgcatagct tacattatct attttctttt
     8221 ctctccatgg gcgttgtttc ccacttttcg tcatatcttt taacgtttta ttatcttgat
     8281 tttcggttat acttctagta gtattatatt gcatataaaa agacccccag tattatttaa
     8341 gattcgacac cttaataata taactggggt tttttattgt caaattttcc tttcacgcac
     8401 aaaaacacgt ttaaacactg taatatcaac agttacagct atatatataa aatcgagtta
     8461 tttctatata gtatcaagac aagaagaaac tcgttcacac tcgtttcaaa aaacaaccta
     8521 ttccttcttc tttttatgac cctctaaacc taaataaatt aatgtgaaaa ccaatgaata
     8581 aataaaactt tctaaaaagt caaaaggatt atcaaataaa atcgaattaa caaaattaaa
     8641 aattaaaaat acagataata aaataatcaa aaagtaaaaa aacttattca tattaaactc
     8701 ctttgttttt atatgttaat attatattga attcatttaa ataacaaaac aagggggcat
     8761 ttacaatgaa tgcaattcaa aacagtatat cactaagaaa gattttagta gtatctttaa
     8821 gtattttaac catactttca atggtcttgg attttaattt caaagaagct caagcccaaa
     8881 acaaaaataa cattgcagat aaaaacgttg aaactttaaa cgaaaaagaa attgaaaaag
     8941 aactaaaata catatatggc aaaattatta ttttagataa agacggaaca gctaaagatg
     9001 ttaatctaga aaatgccaaa tctcgatatg gatatgttcc tgaaggattc caaaaactaa
     9061 aaaacgacat agagaataaa aagaaaacta gttcaatatc acctagagca gttggtggga
     9121 actacaaaaa tagcggtgac tgtttctatt ctgaagtttt aaactcatat ggagaacttt
     9181 taactggaaa cataatcaca gcagtttttg aagatgttaa agccaaaaac ttaaagggcg
     9241 tagcaaaaaa attagctaaa attgggataa aaggaaacct agctggaatc gcagctacta
     9301 tggtttcgaa ggatgtacaa tgtaatctta aatacgggtt actttagata ctatttattc
     9361 caattgcttt attgacgttg agcctcggaa cccttaacaa tcccaaaact tgtcgaatgg
     9421 tcggcttaat agctcacgct atgccgacat tcgtctgcaa gtttagttaa gggttcttct
     9481 caacatcaat aaattttctc ggcataaatg cgtcgtctat tttttattat cttcatgata
     9541 atcatatttt tcttccatct cgtcaaaagc atcatcttta tagaaaaaca aaaagtaagc
     9601 aacaacacca ataggaataa aaaaacagtg tgaaaacaag aagaaactcg tttcaaaatc
     9661 ccctcaaata ttctaattat tctttttgaa attcataacc ttaacaacca aataaatagc
     9721 atttattccc atcaaaataa catacggaat taatatatat aaattttcca aatgagatat
     9781 aaaaattaat ccaagtaaaa agaaaacatt taaaatagtt gctataacgt aaccttcatc
     9841 taacactgtg tttttattca aaataaacac tcctttttta aaaaacttta tcacaagact
     9901 tactcaaatt ataaatacct ttattttgag ttttaagggg gtattttaaa ggtttagggg
     9961 gtatcatata ggtttttaac ttaaaaatat atacaagctc ttaaaacgca aatatgagcc
    10021 aaataaatat atggtaattt cacaaacaaa aatttcagca aaaccagtga ctaatttttt
    10081 aacactgccc atttacatgc aaattaaaaa ttagcataaa atcctttaaa acttccacat
    10141 gtttttctaa attcctgcag ggcgtttttt atcaaaaatc gagaattttt aatttttctc
    10201 taaaaactcc gtaagagcat aaggagaatt tgctatcatt caaaaatgat aggtctggca
    10261 aagccagaaa ttccaggggt tttaaggtat tttaaagtga tatcatacaa agctgtactg
    10321 tcttattttt gtgacacaat atattgcgtt tgtcttattt ttgtgacact acatacagca
    10381 tttgtcacaa aaataagaca gtactttttt ataaaaaatc aacaaaaaag acattagtca
    10441 acactaatgt cttaaataat aattttgctt ttcgaaattc caaattgcgg taattgaatg
    10501 tgctttttct tcttcgtctg ttgttttatc ttcatcactt gcattaatca aattaccatc
    10561 ttcgacatcg tctaagttta aaattttatg tttttgttta agcaatccac cataacttaa
    10621 catacgtttt cgatacaaac cttttggttc tgttgcaaag taaaaaaata tagctaacca
    10681 ctaatttatc atgtcagtgt tcgcttaact tgctagcatg atgctaattt cgtggcatgg
    10741 cgaaaatccg tagatctgaa gagacctgcg gttcttttta tatagagcgt aaatacactc
    10801 aatacctttt aaagtattct ttgctgtatt gatactttga taccttgtct ttcttacttt
    10861 aatatgacgg tgatcttgct caatgaggtt attcagatat ttcgatgtac aatggcagtc
    10921 aggtttaagt ttaaaagctt taattacttt aaccattgct accttcgttg aaggtgcctg
    10981 atctgtaatt accttttgag gtttaccaaa ttgtttaatg agacgtttga taaacgcata
    11041 tgctgaatga ttatctcgtt gcttacgcaa ccaaatatct aatgtatgtc cctctgcatc
    11101 aatggcacga tataaatagc tccattttcc ttttattttg atgtacgtct catcaatacg
    11161 ccatttgtaa taagcttttt tatgcttttt cttccaaatt tgatataaaa ttggggcata
    11221 ttcttgaacc caacggtaga ccgttgaatg atgaacgttt acaccacgtt cccttaatat
    11281 ttcagatata tcacgataac tcaatgcata tcttagatag tagccaacag ctacagtgat
    11341 aacatccttg ttaaattgtt tatatctgaa atagttcata cagaagactc ctttttgtta
    11401 aaattatact ataaattcaa ctttgcaaca gaacctcatt tactatatgg gcatctcttt
    11461 cattattaat acaaagcttt gtatctccga tattaggcaa aggtgtaaac gaattaggtg
    11521 atactatagg attcaacatt atattaatcg tttctttaat aatgattatc ttcttatttt
    11581 ttataaatcg tagtaaaaat atctcctatg attatataaa agttcaaaga ggtgaagcca
    11641 atgaataaat tagaaaaatg gtctttggta tttattattt ttacatttct ctcttcatta
    11701 gcacttttat atttcaaata taattttagt tcggttatgc cagtcctaag tctttctatt
    11761 ttaactatac taatattgtt gacgagtatt attactgtag tttcagttaa tgatgaagat
    11821 acttaaaacg ttcattagtg aaacaggtat tatattaaaa aagcgtacga atttgtacgc
    11881 ttttttcttg tgttattatt aaaatctcat aacaggaaaa tattatgaga ttttagacgc
    11941 tgtcagaacg tctcttttac atcgagtgac attgaatcaa agtctttgta tgttaatgat
    12001 atataaaatt atttagtaga ttcattatag taagctagat tagttgctct acttgttttt
    12061 attctctttt gcctctaatt tattgagata acgataaata gttgtacgtg aaacttgcca
    12121 ctgctctgca attgttttaa ttggcgtacc attatcataa agtgtcttaa gtaagtttaa
    12181 atcttgttta tttaattttt caggtctacc tccatatcgg cctctagcac gtgctgcaat
    12241 tcgaccggct gatgatcgct ctaaaattaa attacgttca aactctgcaa atgctgcgaa
    12301 taaatgaaat aataattgtc ctgtagaact tgatttatcc atcgttatat tttcttctaa
    12361 actatgaaaa ctcacacctc gttcgttaag ttcattaact aacgtgatta aatcctccat
    12421 gttccgtcct agtctatcta atctccaaac aacaatcgta tctcctgacc tcgcaaattc
    12481 aattgcttta tctaaaccag gtcgcttact ttttgaacca ctcatatggt cattaaatat
    12541 cttttcacaa ccatatgtat ttaatcgatc ctcctgtaaa ttcaaatttt gtaatccagt
    12601 tgaaactctt gcataaccta ttttcaaaat acagacctcc tatatacacc tttagtgtac
    12661 cataacttga ttacgaggtc ttttgtgaac atagattttt tgttgggttt ttgaacacat
    12721 aattctatgt aatacttact tatttagaca aaaaacaaga gtgtacagaa aatggttatt
    12781 ttctggacac tctcatcttt aataatatat tttaaatgtc attaacaaaa ctaatttaat
    12841 aagagtcaag tatggtttac atatgtatta tgtttgaaac atacctctaa ttacttttta
    12901 ctaatatcat ttaaaatgtc tcgcaattct tcaatttctt tgttatttaa ttcttcattt
    12961 ttcgcaaaat tcagcactaa acttttcata tcccctccat acagtttatt aagaaaggtt
    13021 ttagcagttt tcattttaat atcgtcttct ttaatatttg atgagtaaaa ataaatattt
    13081 tctgatttgt atcgttttat aatctctttt ttatatagtc ttgtgattaa tgttctaatc
    13141 gttttatcac taacttcttt atatttttga atttcaacta caatttcatt agctgatact
    13201 gattttttat cccatattat attcataaca tcccattcag ccatagatat ttcaacttgc
    13261 ttattggtca tttaaaacac ccattccttt taatattttt tcacttatta attcagcatt
    13321 tttcccagac gggtttccat ctgataaatg tgtagcaaaa taatacttat catgatttgt
    13381 aattacgtaa cctacaaacc acccattatt atacttcccg tttactatac ctgtacctgt
    13441 tttcccatac agttcatact tttcattttt cttaatcaat aatgaagaag ataattgatt
    13501 ctttgctttt ttactaaaat ggttattttg ttccatcata tttttaaaaa ctattacttg
    13561 ttcaagatta gatattttca aactatcttc catccaatag cttttataac ttcccaaatt
    13621 ttcattacca taatttaatt gcttgagttg agccgcagta tagttctttg gtatttgatt
    13681 actaatacgt tcgaagtacc aattaactga attttgcatt gctgtattta aatcttgttc
    13741 cttattccaa gactcgaaaa gataatgttt atgattccat gacatacgtg aatttttatc
    13801 acttataata tgacggtcaa gtccaaacag tgctaaataa attttgtaag ttgaatcagg
    13861 agaatatctt tttctacttt ctttttcatt ataaatatag tatttgtctt tcttcatgct
    13921 gtacataacg aaagatccac tatttgaacc aaaattttta ctttcatcta aaatttggta
    13981 atcgctttgt aagggctttt tataattata atcagttaag gattgcccca ttaaaaactg
    14041 gctttgaatt atcatgataa aaaaagtaaa aatacaaata aaaattagaa ttaattttga
    14101 ctgctttttc agatcggctt cttttatatt aattaatcta cttttgagta atgatttttt
    14161 accattaaat gaatggctta atatattttt gttggaaaat ggggttttta atacggagtc
    14221 cataatagat tccgcataag ttttaaattc atttttgtta atattattaa ggacaaatct
    14281 atcggcttct acttcattgt catgaattat ctttcttttt acaatatgta ctaatggatt
    14341 gtaactcata ataatagaga agatattaaa gataattaaa tgtaaagtat ctctattttt
    14401 agcatgagca tattcatgca gtattatata ttttagtctt ttatcaatta cacttttaaa
    14461 atatgaacta ggaatcaaaa taatatattt cccataccaa aaagttattg gagattgaat
    14521 agcctctgct tttcgaatca caatattttt tttatattga tggttgaaaa gtatcgtatc
    14581 tattttattt ttttcatttt cgtttagata aagtgactgt ttctttaaat atttaagata
    14641 taataaggct ttcaaaaatt taaaacttaa aataataact aaaactatcc aaataactgt
    14701 gcagatatta tcaattgaat cccaattaaa cttatggata tctgttgtga actcttgaat
    14761 aggtttggtg gtatttatgt tatggttcaa atcgtgtgac ttactttcaa ctgtgggcgc
    14821 ttgattattc acattattaa attttataaa agagaattta attgggataa aaggaattaa
    14881 tccagcaagc atagttagat accaaacttt ataatttaaa ctataattaa aatagcgttt
    14941 taatatgtac ctaaaaaata ctaacaatag aaatataaaa caaaagctta ctacgctcat
    15001 tattagtaat ttagccattt tgacaccttc tttcaaatat ttataataaa caattgacat
    15061 aaatattaca attgtaatat tattgattta taaaaattac aactgtaata tcggagggtt
    15121 tattttgaaa aagttaatat ttttaattgt aattgcttta gttttaagtg catgtaattc
    15181 aaacagttca catgccaaag agttaaatga tttagaaaaa aaatataatg ctcatattgg
    15241 tgtttatgct ttaaatacta aaagtggtaa ggaagtaaaa tttaattcag ataagagatt
    15301 tgcctatgct tcgacttcaa aagcgataaa tagtgctatt ttgttagaac aagtacctta
    15361 taataagtta aataaaaaag tacatattaa caaagatgat atagttgctt attctcctat
    15421 tttagaaaaa tatgtaggaa aagatatcac tttaaaagaa cttattgagg cttcaatgac
    15481 atatagtgat aatacagcaa acaataaaat tataaaagaa atcggtggaa tcaaaaaagt
    15541 taaacaacgt ctaaaagaac taggagataa agtaacaaat ccagttagat atgagataga
    15601 attaaattac tattcaccaa agagcaaaaa agatacttca acgcctgctg ctttcggcaa
    15661 gactttaaat aaacttatcg caaatggaaa attaagcaaa aaaaataaaa atttcttact
    15721 tgatttaatg tttaataata aaaacggaga cactttaatt aaagatggtg ttccaaaaga
    15781 ctataaggtt gctgataaaa gtggtcaagc aataacatat gcttctagaa atgatgttgc
    15841 ttttgtttat cctaagggcc aatctgaacc tattgtttta gtcattttta cgaataaaga
    15901 caataaaagt gataagccaa atgataagtt gataagtgaa accgccaaga gtgtaatgaa
    15961 ggaattttaa tattctaaat gcataataaa tactgataac atcttatagt ttgtattata
    16021 ttttgtatta tcgttgacat gtataatttt gatatcaaaa actgattttc cctttattat
    16081 tttcgagatt tattttctta attctcttta acaaactaga aatattgtat atacaaaaaa
    16141 tcataaataa tagatgaata gtttaattat aggtgttcat caatcgaaaa agcaacgtat
    16201 cttatttaaa gtgcgttgct tttttctcat ttataaggtt aaataattct catatatcaa
    16261 gcaaagtgac aatagcattt tacaagtatt ttttattgtt cgattagggt aaacctaaat
    16321 aatacataaa ttatattaca atatgtttat tatagaggct aaagtatctt agaaatttgg
    16381 atagtaggtt tttcgggaat aaaagtatag ttggctttaa tatataatta agctaagcta
    16441 tcatttatat ttactcgatt ataattcgca cttcaacttt tttataacgt aaaaattaaa
    16501 acgtagtttt atttatcttt agtaatatct ttttaaacac tacagtttct tcattagtta
    16561 aattagcgaa gtaatgatta ttaagttgat aggctttctt ttctaatgtt ggccataagt
    16621 cttttgcttt atttgtactg tttattagca cagttcttct attttcatta tcagtttgac
    16681 gtgttattag atcctttttg gacatcttat ctaatattcc agatattgtt gaaggttcta
    16741 aatttaaagt attaccaatc gctttaggtg tattcaaatt actattaatc aagcaattca
    16801 aaacaccata ttctgctgga gtaatattat agggacttaa taaactttta aaatgtttaa
    16861 aaactctatt ctgagaagta ctcaacaaat aatttataca attatctaat tccacaacta
    16921 aaacctctct taaatcatta gtattgactc gcttatcata tcatgataag ttttgtagga
    16981 aaatagtttt gcaacaaaaa catacttcta caaaacaatt gtgaaagaag gctaataaat
    17041 gttcaatgcg gtagtagtga gaaaaagtgc atcaaatgtt agttataaag tagaaaaagt
    17101 tgatgaatct catttatcga agggtgatgt attagtaaaa gtggtatact cttcaataaa
    17161 ttataaggat atgctagctt tacaatataa aggcggtgta attagagatt atcctatgat
    17221 tcctggtata gattttgcag gtattgttga atcaagttcg aatgataagt ttaaagaagg
    17281 cgataatgta ttagttactg gttatgatgt tggcgtgaca catacaggtg gattttcaga
    17341 atatgcacaa gtgcctggag agtggattgt tcctattccc caagaaatgt ctattaaaga
    17401 gtctatggta tatggcacag ccggttttac ggcagcatta tcaatttttg aactagaaaa
    17461 atatggaatg aatatcaaat cacaacctga aattttagtg tctggggcta caggtggtgt
    17521 gggcagtgtt gctatacaaa ttttacataa aattggatat gaaaatatca ctgctatcgt
    17581 aagaaaagaa aagcaaatag aaatcgcaaa aaaattaggt gcaaaacaag taataataat
    17641 tgaagatgat aataaaccgc ttaaaaaagg tatttttgat tatttcttag atacagtggg
    17701 gagtaatgta acattatacg gtttaaaacg tctaaattat caaggtgttg ctactgtatg
    17761 tggaaatgta gcaggaaatt cacttaacgc taatatatta ccgtttattc ttagaggtat
    17821 taaattaatt ggcattgatt ctgtatatgt tgatcataat atccgtgaag atatatggag
    17881 taagttagca aatgaatgga atataggaaa ttcacttcta tacaatgaaa ttggatttga
    17941 agaattctat aaaacgatag atcagctttt aaaaggacaa catttaggaa gaactatttt
    18001 aaaagtataa gtgtgagtat tcattaatac atttactatt aattcaatca ttttgcattt
    18061 ctctactaac cagtgttata atttatataa cgaaaatgat taacaattaa tgcaccaatc
    18121 cccacactat tgcagtagtg tggggatttt ttcgatgctg gcttataaag tcgcctatta
    18181 attatttgtt gcgtttacta agccaataag tataatacgc aacagcacag ccactgatga
    18241 ctggtgctat gatgtgaacg aaaatgatta gcaaagtaat gcacctcctc tcttcgtcaa
    18301 ttgacgcctg agagataggc gactctatta ttataccatc tgtgaatata caagcatatc
    18361 tacttccgat aagtcgtctt atgttatata actttgtttt ttatagtatc aagacaagaa
    18421 gaaactcgtt tcaaaaaccc tcatgatttt tagagaaaaa ctctcttatt tcatcgtctt
    18481 taataaaata atatgccatc tttccatctt tataaaaatc aagtacctca tttttatata
    18541 aaagccttaa atgatgtgaa gttgaagcaa cactcatttt caatatcaaa gaaatatcac
    18601 aaacacacaa ctcatcttct ttaatcaaag ataatatgat tttcaatttc ttctcatcac
    18661 aaattttttc taaaatgtta agtaatttct tagatttatc atcttctaaa aaacttaaag
    18721 cattgttaac tttatcctca tgtacacaga tcacatcaca agtattttca taactcatat
    18781 aaaatcacac cctaaattaa aatataaatc ctaaaattgt ttgaatagtg tcattttcaa
    18841 taataataaa taaacctaaa gctatataaa taatagccat aatccaacga ctaaatttct
    18901 caacaatttc tccaattcct ggaatattag ctaatttttg tgcagtaaac accaagaaga
    18961 aaattaaaat taaaaagaca aacagagtaa gtaataaatt agtaacactt aatgtcacaa
    19021 aatacggaac aaataaacca atattatcgg cgccacaact tgctatcgta acaattgcaa
    19081 ccgtaccaac taatttagac aatccttttt cattcaattc ttttttagct ctcttttctc
    19141 cttcacaatc atcataaata gccactttaa ttccaagata aattggtatt aaacccaata
    19201 aacctaatat ccacttttct ggaacataat ttaatacaaa agctaaaaac aaactaacta
    19261 atattaaaat aatagaccct aaatattgac caacataaat atctctatat tcttttctag
    19321 tctttgctct agcaaaaaat attaataaaa ttactaataa atcaactgct gtagcaatat
    19381 aaagaacagc agcagcaaca accgtttgaa tcataataca cctcattcaa aaatattttt
    19441 gaatgtatta taacttatat ttttaaataa tcataggtgc tttattccaa ttgctttatt
    19501 gacgttgagc ctcggaaccc ttaacaatcc caaaacttgt cgaatggtcg gcttaatagc
    19561 tcacgctatg ccgacattcg tctgcaagtt tagttaaggg ttcttctcaa catcaataaa
    19621 ttttttcggc ataaatgcgt gtctatgcgt agacatggag acacttcaga attatggagt
    19681 gattacatga gtttaactat ttttctttat tcagttttag gaagtttatt agcaaattat
    19741 atctacgaaa aatcttcaaa ataaataact ttttcggttc tactttgtac actttatcta
    19801 cctggtagac ctaattgtta ttgctttaca ggtctaaaat tcgtcgttat aatctagtta
    19861 aatcccgtaa gggcgcactt atacgtcgga taaatcgaca tgtgcaaaaa cgtaatcgac
    19921 cttcgtcgat ttttttattt caaaattaaa gaaacggctt gagatattcc gagcagttat
    19981 aaaaattaat ttgcgttgaa tattgctact acattcttga aaaagtgatg tagatttata
    20041 gcccataact tttttgaatt acatcgacga tacggcgtcg aaagaaaaat aaatagaccg
    20101 tatgaaagaa aaagctacct cactttatct ggggtagctt ttatttttta tgcccttatt
    20161 ttgaatttta agagggcatt ttaaagattt aggggtgatt catatagttt tatatctaaa
    20221 acttatatat gcttttaaaa cgcaaatatg agccaaataa atatatgcta ttttcaaaaa
    20281 caaaaatttg agcaaaaaca ataactattt ttagacactg cccatttaca tgcaaattaa
    20341 aaattagcat aaaattcttt aaaacttccc cacgtttttc taaattcctg tagggcgttt
    20401 ttatcaaaaa tcaagacaag aagaaactcg ttcacactcg tttcaaaaaa acaagaaatc
    20461 taatctatac acctaccgtt ttccaacccc ctcaaagcat acaaattaaa aacaaaatta
    20521 ttcataatct tactttcttt taacaaaaac ataaaaacca taaatagaca aattaactat
    20581 caaaggcaat aaacagtata aaaaaaccac gaataaatct tcatcaacat ctaaaataaa
    20641 aaagaataaa acaattaaca aaatactaat taacaaacct aaaagtggca aactttttat
    20701 atatttttct aaattttcat tcataaaata gactcctttc aaaaatatgt ttataaatat
    20761 attaaaataa atattgattt tataaagcgc ttacttatac aattaaaata tcttattatc
    20821 ttggaggtat caaatgaaaa ttataaaatt attttcaata atttccttgt tcctactggt
    20881 atttagcgcg aatttttcta atgcttacgc aaatgaagaa caaaaaagtt ctttactaga
    20941 aaatcaaaaa gaaaaattga aaagcaaaaa catcgaagta tcacaaatga ccaagaaaga
    21001 aataagtttt ctagaacaat tgcaaaataa aaatgaagat atgcaaaaat tcgaaaagca
    21061 aatgaaaaaa gaaggattta aaaaaataaa gctagaagac aaaaattcta aattaaaata
    21121 tctagctaca gaagcaaatg ataaaaatgc atatggctac atagctaata acgcttataa
    21181 aaatgaaaaa acaaaagaaa ttgtagtttc tgaaacaata tatgataact acaacaaaaa
    21241 aatcacaaaa ttcattgccg aaaaaagaag tatgactgaa aacaaagagg gaaaaatact
    21301 tattaacaaa aattacgttg aatataaggc tgaaaaagtt gataaaaaca gaccggtaac
    21361 atatgcagga ttcaaatgga acggcaaagc attcgcttgt agtatggctg gactttatgc
    21421 atgtgctcac tactgtggag tatgggcaat cgtaaatcca atagccggcg gtgtatgtga
    21481 agcagtttgc ggaactgcat ttgcagctgg atgctctgta ggttgatttt attccaattg
    21541 ttttattgac gttgagcctc ggaaccctta acaatcccaa aacttgtcga atggtcggct
    21601 taatagctca cgctatgccg acattcgtct gcaagtttag ttaagggttc ttctcaacat
    21661 caataaattt tttcggcata aatacgatgt tccttattta tcctcataaa aaacaatagc
    21721 tgaaatatat aaccaattac tgtgtgtttg aatttctaat acatgaatat cattctttaa
    21781 aaacctatta acttgtttat ctaattgacg atgagtaaaa gtagcgaaag ttttaatctt
    21841 catgatatct ctccttttat aaaaatagca atccttatta caatattaaa cacttttatt
    21901 ttggatttta agaggcattt tgaagactta gaggcaaatc atataggttt tgtacttaaa
    21961 aatctataca gtctcttaaa acgcaaatat gagccaaata aatatatgct aatttcacaa
    22021 acaaaaattt cagcaaaatc agtgactaat tttttagata ctgcccattt acatgcaaat
    22081 ttaaaaatta gcataaaata ctttaaaact tccccatgtt tttctaaatt cctgcagggc
    22141 ttttcttatc aaaaacttag aaattttaat ttaactctaa aatctccgta agagcataag
    22201 ggaaatttgc tatcattcaa aaatgataga tctggcaagg ccagacattc caagggtttt
    22261 aagttatttt aaagtgatat catacaaagc tgtagtgtca cacttttgtg acactacata
    22321 cagcatttgt cacaaaaata agacagcact tttttacaga aaaacaataa aaaaagacat
    22381 cagttatcac taatgtctta aataataatt ttgcttttcg aaattccaaa ttgcggtaat
    22441 tgaatgtgct ttttttcttc gtctgtcgtt ttatcttcat cacttgtatt aatcaaatta
    22501 ccatcttcgg catcgtctaa gtttaaaatt ttatgctttt gtttaagcaa tccaccataa
    22561 cttaacatac gttttcgata caaacctttt tctaaatcac ttacaatttc ttgatttttt
    22621 tcgtcgtcat cagttaaaaa gtcagatgat ttaacggaat attttgatgt ctcttcgagt
    22681 gttataaaat catttgaatt attgattaaa gatattatat tgtttcatgt ttttacggcg
    22741 catataaagg gcatgtgttt cttcaagttc agttagaatt gtttgcatta aataagcttg
    22801 cattgacttg attgtttcct tttggccttt aactccccta tcatgtatag cttttttaag
    22861 tctttttaaa gaagttaata tttcatcctc aatgtcctct aacatgtaat gcatatcttc
    22921 atgccttgaa ttaaatgatt tttttgcttt aagaataaca gcctttatga tttctaaatc
    22981 tctataatca tattttaata aataattagt tagttgttct gggaattctt gcaatagcat
    23041 ttctttatca tcaaaattat gtgtaaattg atttgaatga tttgaatgat tactaatttc
    23101 atttttgtac tttatatcat tcaagtcatt catatcatta ttctcagtat cattaaagtc
    23161 aatgtcatta aagtcagtat cattagtgtt cgattttcga acttctggac gttcgatttt
    23221 cgaacttctg gacgttcgat tttcgaactt ctggacgttc gattttcgaa cttccttctc
    23281 gccgtaaggt tcaacatcgt tttcttcttt ttctattttg taaatatcac gttctgtgac
    23341 aataggtttc attaaatata gaatatttgg tttatttaaa ccacgtcgtt tttgaatgag
    23401 tagaccatcg ttttctaacc ctttttttat ttttgttaac ttttcttttt tacaatttaa
    23461 gatttccatt agcttttcat ttgaataaac aaagtaaatg ttaccatctt catcaaccca
    23521 gctattttta atagataaat ttaagcgatc acgtaagata gcataggcta ttttcatatc
    23581 attagttaga tttttataat tttcactggt aaagaatact ttagggattt gataaaatct
    23641 ttctttgtaa ttttcttgca ctgtaaaata ttgattttgc atgacaaaaa acctctttcc
    23701 atattttagt ttggtaagag gtaataaaac gtttttattt agctttacat ttatttaatg
    23761 atttaggtgc ttgcactaag atattattca ttatataata caagtatcga aaattatata
    23821 aataaacagt ttctaaacgt tttattacca aaccccgact attaccagta gttggggttt
    23881 ttgttatatt aagtttatta tagcacttta aataaactta taaaagggaa aatatagctt
    23941 tatcaagggt ttataaaccc ttgataaata tcataaacct ttcataaacc cttgataaaa
    24001 aggttgatgg atgtttattt ttatttatta atcactttat tattaagcat tataagctta
    24061 taatatttta tcaagggttt ataaacattt tataaagggt tgatgatatg aaaagtgtga
    24121 aaaagttgag tgaagaatta ggggttagta agcaaacgat ttttaataat attaagcgat
    24181 tgaatataga gacaataaaa caggaaaaca cttcgtttat taaagaagat accgatatag
    24241 aaaaaatcat tcaaagagta aatgaaaata aaaagaaata tggttttgaa agtactactg
    24301 aagacaaaca aaaaaaaggg tcggataata ttaattttga atcgaaaagc gatgctcaaa
    24361 tagtagaaat ccttaaaaat cagattgata ctttaaataa tcaaattgaa aaacaagaaa
    24421 gtcgtcatga aacaacaatt gaattttaca gaaaagagtt gcaagaaaga tcaaaattgc
    24481 ttgaaaatca gcaagttctg gcattagaga gtaataaaaa gattcaaaaa ttagaaaatc
    24541 aattagaaaa agaaaaacac cttaattatc cctttgatac atctactaac actagacaaa
    24601 acgttgatgc acaagaaaaa acatatacta ctaatcctgt aaatattaac agagatcagg
    24661 aagaaactaa agaaacagag attcaatata aggatatatc tggaagtcaa agcgacgaaa
    24721 gtacacaagg tgaagaagca aaaaaagaag acgttccagc taatctaaat gacaatgata
    24781 gtgatataga agaaaagagt gaagaaacgg aacctaaaaa ggggttttgg agtcgtttgt
    24841 ttggtagcta aaataattga ttaggcacta aaagttataa aattttagtg tcttttatat
    24901 agtgagaact tctggtaatc atcgattatg taaactaaag tatttcaaat aattaactgt
    24961 attaatactc tcatcatgat tgcgttataa acgttcgtta ttgagacaaa atttaatagt
    25021 actactacac aaaaagagag tgcgaattcg cactctcttt ttgtgataaa tgaatggtta
    25081 agaaaataat tcatccacag ttgtatcaaa caatcttgcc aacttaaatg ctaatgtcaa
    25141 tgtaggatca tatttattgt tttctattgc attaatagtt tgcctagaca cttttaattc
    25201 tttacttaaa gtttcttgag aaattccttt ttgttttcta tattctctaa ttctattttt
    25261 cattaattta acctttagat gtatattttt tatttgtagt atagtaatta aacagcataa
    25321 gaaatagtgc tacaattata aagaaaattt ctggatattg agaaaaccaa gatccttcaa
    25381 tacttggtga caaacctgta aatttaagca ctagtgtaaa taacatacaa tatacaatcc
    25441 aaataaaact tttagccagt atttcaataa acattttacg ttgtctttca tcgtatcgat
    25501 cttgttgtcc ttttttatct aatgtttctg aaggtaaata tttgttagtt atagccgtcc
    25561 ataaacaaga aaaaattaaa ataataataa aaggaattaa attcattata acacctcata
    25621 aatgtaaaaa gtatttgaca tttatgagtg taaatatttt tgatacaaat gtcaaatact
    25681 ttttacatta taatatattt taaaacacct tattagtaaa acaattacta tatagaaagc
    25741 tgcgaactcg tactcttttt tcttgtataa ttattaaaat ctcaattcaa taatatgtta
    25801 tggaatttga gacactgtga gagacgctca tttgcattga caatcaattt atcaagataa
    25861 tcccttatca tgtttaattc tataaactgt ttgtcttgtg atattaactt ctttcgcaat
    25921 cttactaatc gctttgcctt cttctaacat ttccaccacg cgatgataaa taacacgttt
    25981 ctgtgggtct ttagcatttg gtgaataaag taaagggcgc cctttatata cgcctttttc
    26041 cttcgcaact tgaatccctt gcgcttgtcg acgtttactt tcatttctct cttgttctga
    26101 aaccattgct aatatttgaa tgattaaatc tttcataaac ttatccagta atggattgcc
    26161 aattacttca ttcatcatag gtaagctggt aatcattaac tgaacgtctt tttcttttaa
    26221 ataattcaca gtttcaataa tttcatcata gttacgtcct aaacgatcaa tagattccac
    26281 aacgaatcga tctcccattc tgacaaaatt gagtgcttct tgaaatacag gtctattttc
    26341 cactgacttt cccgactgtt tctctgtaaa gattttctcc acaccaaacg tctttaaatt
    26401 atccaattgt ctttctaaat tttgatctat cgatgatact ctcgcataac ctataatcat
    26461 tcatcttcac tccataataa atatacaccc taatcatacg ttttaattgt tataatttca
    26521 acaattcttt ttgtatggtt agggtgtact caaagtgtac atatctataa ttaaaactta
    26581 ctaaaaataa atatagattt tttctttgta acagaaccgt tcatttgaag gtcatctcta
    26641 tcataaatat ttaaattaac taaaaatttt aatcatctgt ttaatactta tgaaatgtat
    26701 ttacggtagg tattaaaatt gatgaaattt atataagtgc tttcaatgaa aatgaccgtt
    26761 tatttatcct cctgatttaa ggagttagaa atttcgaaaa cgattctttc catttgttgc
    26821 atttgttcca tgtccagata tttaatacat tatagaaaac caaagaccat cactaattaa
    26881 acgcagtttt aaaatttcat caggattgcc ttcgtcttta aaatgggcct cttttaatat
    26941 aagttctact ctttcatacc taactctttc aatgccatcg tttcatacgc cgattctcct
    27001 gattccatag caaactcagc gataaacatt gggaatactg cattgagttc tattatatgc
    27061 tctttcattc gtggccatat ttcacctcca gctttaccgt atgctgttat aagttgctct
    27121 aatccttcgt cgtcgaatac acgatggtgt cctataaagt ccattgatgg gtcggagtgg
    27181 gttgcttcag tccagtctat gagacctgtg acgtttgctt ggttatctac cattatatgt
    27241 cctggatgta agtccccatg tatcatggtc gcatgtcgag gccatagttc gtcgttttct
    27301 aaccattgtt tccatctgtt ccataattca tctgatacgc cataagtttc tttaacttta
    27361 ttcattcttc tttgaaagtc attttttatt tcttgtatgg ttttgatatt tatatgctga
    27421 acgttaatgt tttcttctgg tatgttgtgt aaatctacga gtgtttcagc taatgtgtta
    27481 ataaagtttt ctggtaatgg tttgtgttca atttcccata cataattttg tatttctgga
    27541 tctattgtgg ctgcgggttt acctgtaagt tttgggtaag caataaggtc ttttgcatgt
    27601 actttccact tcggtatttc aaatgaaaca ttcttctgta agaagtctac cgtttgtttt
    27661 tcgggttttg ttcgtttata aacgtcaggt cttcttggta gtctcaaaac ccattctact
    27721 ccatgtttat cttttccaaa tgcaacttga aaatcaagtc ccgattcatt caatgagatt
    27781 gtttgaggtt ggatgtgtaa ttgatatttt tctgcacatt taataatttc attatgtcga
    27841 gtcattttat tggatcctta tttctattat atttttcttg tgaacgtatt ttttatattg
    27901 atataaatga acctaatatt caatataaat tagtgtatag tttttaagtt atatcatgaa
    27961 gagattgtcc tgttaattcc cattttttat ctgatacatg tttaacaaac cttgtatcat
    28021 gtgatgtaaa caaaatgatt ccaggatatt tattcataaa catttctaat gcttctaatg
    28081 ttttaatatc taaaaaatta gttggttcat ccaaaattaa catattcgct ttcgttgaaa
    28141 ataatactgc taacgataat ttcgttcttt ccccaccact caaaacatta caagaacgat
    28201 caagtgcttc atttaaaccc aagttattta aaatagctct actgaatgat tctgatgaat
    28261 ccgtttcatc cattaaatat tgcaataatg aaacgtcacg catgtcttca taagcaagtt
    28321 gacgatagta tgccatttgc actttaggag aacaatcaat tccctctatt tggtggtaaa
    28381 tagcttcaag taaagttgtc ttacctacac catttgcacc tacgagcgct atatttttgc
    28441 catatggtat ttggaatcgt acttgtgtta gcagtttttg acttccttta accaatgtta
    28501 gattttgtgc aatgattgga taattattat ggatatcata aattttattt tgtgggaaat
    28561 tgaattcatg ataactttgt ggtttttcaa cttcttccaa atgttccatt cttttttcaa
    28621 tatgcttagc ttgtttttga gcagccttct caaccgtgcc tttttgtttt gatgcactta
    28681 aacgatctgg tgctatactt ttgttttttt gttttgatga tgcttgtgcc atttgttgcg
    28741 cttgatttcg tttagcttta ctggcttggg acaatctttg tttttcactt atatactgtt
    28801 catattgacg ttgttgttct aactgttctt gttcatattg attttgatac tgtgtgtaat
    28861 tacctttaaa cactcttatt gtgccatctt cttgtatatc ccaaattgtg tcagcaattt
    28921 ggtctataag tgctctatca tgacttacta taattaaagt accatagtaa tattttaaaa
    28981 tatttttcag ataatcttta ccaattttat ccaagtgatt tgtaggttca tctaaaagta
    29041 atatcggact ataatttgat atgacattag ctaatttata ttttgctttt tcaccaccac
    29101 tcatactgtc ggttgtatgc ataggtatat ggagttcact cattaaacta ccgtctaacg
    29161 tgttaaaatc attttccaca tccatgttaa gctgttcaaa atattgaatt tcgccaaccg
    29221 tttcaactgt tccagattct ggttttgttt tttgagcaat catatttagt aatgtggttt
    29281 tgccagtacc attaccccca ataagtgcta ttttttcaaa ttggtaagcg taaagatgac
    29341 cgatgttaag tgatcgtaaa tctgtcaatt tatgattgat ttggttaaat ttaattgtat
    29401 attgttccat atttatacac tccttgtata tttaaaggac gtgtacgcaa aaaaatgaga
    29461 caggctactc ccgtctcatt cacattacac tttcaaacac ttaaaaattt attatgatgt
    29521 tttagtattt gaaagcgttt attattccta tcgaaggata aaaaatgaca taagtcatcc
    29581 tatgagtgtg tattgcggac aagccttttt gaattaattt agttttgtat tcaaaaaggt
    29641 ttatttgagt ctcatagaag ctgtcatttt aatcctcctt catcgataaa atagtaatgt
    29701 taatataaca ttttgttggt ttttttacaa tatatctcta agtagaaaga ttatataaca
    29761 aaagtataaa aatacaattt tagattgatt atacatctcc ttaatttaga gtgtactcat
    29821 aaaatacggt tctgttgcaa agttgaattt ataatataat tttaacaaaa aggagtcttc
    29881 tgtatgaact atttcagata taaacaattt aacaaggatg ttatcactgt agccgttggc
    29941 tactatctaa gatatgcatt gagctatcgt gatatatctg aaatattaag agaacgtggt
    30001 gtaaacgttc atcattcaac gatctaccgt tgggttcaag aatatgcccc aattttatat
    30061 caaatttgga agaaaaagca taaaaaagct tattacaaat ggcgtattga tgagacgtat
    30121 atcaaaataa aaggaaaatg gagctattta tatcgtgcca ttgatacaga gggacataca
    30181 ttagatattt ggttgcgtaa gcaacgagat aatcattcag catatgcgtt tatcaaacgt
    30241 ctcattaaac aatttggtaa gcctcaaaag gtagttacag atcaggcacc ttcaacgaag
    30301 gcagcaatgg ctaaaataat taaagctttt aaacttaaac ctgactgtca ttgtacatcg
    30361 aaatatctga ataacctcat tgagcaagat caccgtcata ttaaagtaag aaagacaaga
    30421 tatcaaagta tcaatacggc aaagaatact ttaaaaggta ttgaatgtat ttacgctcta
    30481 tataaaaaga accgtaggtc tcttcagatc tacggatttt ccccatgcca cgaaattagc
    30541 atcatgctag caagttaaac gaacactgac atgatatatt agtgattagc tatatttttt
    30601 actttgcaac agaaccagcc atttaatatg actgttacaa ttactaagat tcaagcacta
    30661 ttacgccgca cgtatgattt caccactcaa gttaataatt taacagtaga tgattgcgag
    30721 ttactacttg atgcagcaaa gcttaaattt aatgaagaaa ccatagacct gacacacact
    30781 gaattgcaaa tcatgcatag cttattccag aacaagggca aattcgtcag tcgtaatgcg
    30841 ttaatcgaaa aatgctggga atcagaacac ttcattgatg acaatacgct tgctgtcaac
    30901 attacacgtt tacgcaaaaa gctacaaaaa ctaggactta cagattttat cgaaacgaag
    30961 aaaaatgtcg gatatcgtgt aggtgacgta t
//
