LOCUS       CP030657               29669 bp    DNA     circular BCT 10-OCT-2019
DEFINITION  Staphylococcus aureus strain ER04448.3 plasmid unnamed2, complete
            sequence.
ACCESSION   CP030657
VERSION     CP030657.1
DBLINK      BioProject: PRJNA470993
            BioSample: SAMN09484070
KEYWORDS    .
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 29669)
  AUTHORS   Sullivan,M.J., Altman,D.R., Chacko,K., Cliferri,B., Webster,E.,
            Deikus,G., Lewis,M., Khan,Z., Beckford,C., Rendo,A., Samaroo,F.,
            Sebra,R., Karam-Howlin,R., Southwick,K., Adams,E., Ying,L.,
            Kornblum,J., Factor,S., Danesh Yazdi,M., Dingle,T., Hamula,C.,
            Bashir,A., Schadt,E., Kasarskis,A., Patel,G., Wallach,F., Gibbs,K.
            and van Bakel,H.
  TITLE     Whole genome sequencing to identify and define MRSA outbreaks
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 29669)
  AUTHORS   Sullivan,M.J., Altman,D.R., Chacko,K., Cliferri,B., Webster,E.,
            Deikus,G., Lewis,M., Khan,Z., Beckford,C., Rendo,A., Samaroo,F.,
            Sebra,R., Karam-Howlin,R., Southwick,K., Adams,E., Ying,L.,
            Kornblum,J., Factor,S., Danesh Yazdi,M., Dingle,T., Hamula,C.,
            Bashir,A., Schadt,E., Kasarskis,A., Patel,G., Wallach,F., Gibbs,K.
            and van Bakel,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUN-2018) Genetics and Genomic Sciences, Icahn School
            of Medicine, One Gustave L. Levy Place Box 1498, New York, NY 10029,
            USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.2.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 245.827080652x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 06/29/2018 15:58:08
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            Annotation Method :: Best-placed reference protein set; GeneMarkS+
            Annotation Software revision      :: 4.5
            Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region
            Genes (total)                     :: 3,033
            CDS (total)                       :: 2,951
            Genes (coding)                    :: 2,860
            CDS (coding)                      :: 2,860
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 91
            Pseudo Genes (ambiguous residues) :: 0 of 91
            Pseudo Genes (frameshifted)       :: 47 of 91
            Pseudo Genes (incomplete)         :: 40 of 91
            Pseudo Genes (internal stop)      :: 25 of 91
            Pseudo Genes (multiple problems)  :: 20 of 91
            ##Genome-Annotation-Data-END##
            Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..29669
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="ER04448.3"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="unnamed2"
                     /geo_loc_name="USA:New York City"
                     /lat_lon="40.7903114 N 73.9528738 W"
                     /collection_date="2015"
                     /collected_by="Mount Sinai Hospital"
     gene            join(28700..29669,1..2)
                     /locus_tag="DQV89_14990"
     CDS             join(28700..29669,1..2)
                     /locus_tag="DQV89_14990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH:quinone reductase"
                     /protein_id="QFM60895.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFEEFYKTIDQLLKGQHLGRTILKV"
                     /name="NADPH:quinone reductase"
     gene            complement(174..266)
                     /locus_tag="DQV89_14995"
     CDS             complement(174..266)
                     /locus_tag="DQV89_14995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="QFM60867.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(423..770)
                     /locus_tag="DQV89_15000"
     CDS             complement(423..770)
                     /locus_tag="DQV89_15000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="QFM60868.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="transcriptional regulator"
     gene            complement(789..1406)
                     /locus_tag="DQV89_15005"
     CDS             complement(789..1406)
                     /locus_tag="DQV89_15005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017465246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium transporter"
                     /protein_id="QFM60869.1"
                     /translation="MIQTVVAAAVLYIATAVDLLVILLIFFARAKTRKEYRDIYVGQYL
                     GSIILILVSLFLAFVLNYVPEKWILGLLGLIPIYLGIKVAIYDDCEGEKRAKKELNEKG
                     LSKLVGTVAIVTIASCGADNIGLFVPYFVTLSVTNLLLTLFVFLILIFFLVFTAQKLAN
                     IPGIGEIVEKFSRWIMAIIYIALGLFIIIENDTIQTILGFIF"
                     /name="cadmium transporter"
     gene            complement(2522..2716)
                     /locus_tag="DQV89_15010"
     CDS             complement(2522..2716)
                     /locus_tag="DQV89_15010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QFM60870.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     gene            2826..3518
                     /locus_tag="DQV89_15015"
     CDS             2826..3518
                     /locus_tag="DQV89_15015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QFM60871.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVE
                     YKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTA
                     FAAGCSVG"
                     /name="hypothetical protein"
     gene            complement(4382..4698)
                     /locus_tag="DQV89_15020"
                     /pseudo=""
     CDS             complement(4382..4698)
                     /locus_tag="DQV89_15020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002483623.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /name="replication protein"
     gene            complement(4691..5674)
                     /locus_tag="DQV89_15025"
     CDS             complement(4691..5674)
                     /locus_tag="DQV89_15025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="QFM60872.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNK
                     PNILYLMKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSKIERPEVRK
                     SNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNQFTHNFDDKEMLLQEFPE
                     QLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHD
                     RGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication protein"
     gene            6100..6843
                     /locus_tag="DQV89_15030"
     CDS             6100..6843
                     /locus_tag="DQV89_15030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002508633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="QFM60873.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     gene            complement(6961..7083)
                     /locus_tag="DQV89_15035"
     CDS             complement(6961..7083)
                     /locus_tag="DQV89_15035"
                     /inference="COORDINATES: protein motif:HMM:PF08282.10"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QFM60874.1"
                     /translation="MAPYTNKGYAVKELCSYLQINMDDVYTIGDRKLIYLCLIP"
                     /name="hypothetical protein"
     gene            complement(7159..7719)
                     /locus_tag="DQV89_15040"
     CDS             complement(7159..7719)
                     /locus_tag="DQV89_15040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QFM60875.1"
                     /translation="MNRADIFKIFDVELNITIFLGALVATFIYFISYMNNVNELITLCL
                     TLAFPAYLLKISRSFEVILLEEKIKNSKIKICDKDRIEREILVKKNLIDELLFPNRVIK
                     KYTLTILIYSIGIIILLLLCNMLSYGIGENVNFIWRLLACYVTSVTVIIVALIIMIMIF
                     DLIIGLLLNFQIFLKNKKYDDFL"
                     /name="hypothetical protein"
     gene            complement(7924..9468)
                     /gene="qac"
                     /locus_tag="DQV89_15045"
     CDS             complement(7924..9468)
                     /gene="qac"
                     /locus_tag="DQV89_15045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QacA/B family quaternary ammonium compound efflux
                     MFS transporter"
                     /protein_id="QFM60876.1"
                     /translation="MISFFTKTTDMMTSKKRWTALVVLAVSLFVVTMDMTILIMALPEL
                     VRELEPSGTQQLWIVDIYSLVLAGFIIPLSAFADKWGRKKALLTGFALFGLVSLAIFFA
                     ESAEFVIAIRFLLGIAGALIMPTTLSMIRVIFENPKERATALAVWSIVSSIGAVFGPII
                     GGALLEQFSWHSAFLINVPFVIIAIVAGLFLLPESKLSKEKSHSWDIPSTILSIAGMIG
                     LVWSIKEFSKEGLADIIPWVVIVLAITMIVIFVKRNLSSSDPMLDVRLFKKRSFSAGTI
                     AAFMTMFAMTSVLLLASQWLQVVEELSPFKAGLYLLPMAIGDMVFAPIAPGLAARFGPK
                     IVLPSGIGIAAIGMFIMYFFGHPLSYSTMALALILVGAGTASLAVASALIMLETPTSKA
                     GNAAAVEESMYDLGNVFGVAVLGSLSSMLYRVFLDISSFSSKGIVGDLAHVAEESVVGA
                     VEVAKATGIKQLANEAVTSFNDAFVATALVGGIIMIIISIVVYLLIPKSLDITKQK"
                     /name="qac"
     gene            9651..10211
                     /locus_tag="DQV89_15050"
     CDS             9651..10211
                     /locus_tag="DQV89_15050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002504141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="QFM60877.1"
                     /translation="MKDKILGVAKELFIKNGYNATTTGEIVKLSESSKGNLYYHFKTKE
                     NLFLEILNIEESKWQEQWKKEQIKCKTNREKFYLYNELSLTTEYYYPLQNAIIEFCTEY
                     YKTNSINEKMNKLENKYIDAYHVIFKEGNLNGEWCINDVNAVSKIAANAVNGIVTFTHE
                     QNINERIKLMNKFSQIFLNGLSK"
                     /name="TetR family transcriptional regulator"
     gene            complement(10421..11029)
                     /locus_tag="DQV89_15055"
     CDS             complement(10421..11029)
                     /locus_tag="DQV89_15055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="QFM60878.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRDYDEIIETVSYLKEKDVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIVQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRI
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDKGSS"
                     /name="recombinase family protein"
     gene            complement(11515..12414)
                     /gene="mph(C)"
                     /locus_tag="DQV89_15060"
     ARG             complement(11519..12414)
                     /name="mph(C)"
                     /gene="mph(C)"
                     /gene_name="Mph(C) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(12513..13979)
                     /locus_tag="DQV89_15065"
     CDS             complement(12513..13979)
                     /locus_tag="DQV89_15065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002447408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(A)"
                     /protein_id="QFM60880.1"
                     /translation="MEQYTIKFNQINHKLTDLRSLNIGHLYAYQFEKIALIGGNGTGKT
                     TLLNMIAQKTKPESGTVETVGEIQYFEQLNMDVENDFNTLDGSLMSELHIPMHTTDSMS
                     GGEKAKYKLANVISNYSPILLLDEPTNHLDKIGKDYLKNILKYYYGTLIIVSHDRALID
                     QIADTIWDIQEDGTIRVFKGNYTQYQNQYEQEQLEQQRQYEQYISEKQRLSQASKAKRN
                     QAQQMAQASSKQKNKSIAPDRLSASKQKGTVEKAAQKQAKHIEKRMEHLEEVEKPQSYH
                     EFNFPQNKIYDIHNNYPIIAQNLTLVKGSQKLLTQVRFQIPYGKNIALVGANGVGKTTL
                     LEAIYHQIEGIDCSPKVQMAYYRQLAYEDMRDVSLLQYLMDETDSSESFSRAILNNLGL
                     NEALDRSCNVLSGGERTKLSLAVLFSTKANMLILDEPTNFLDIKTLEALEMFMNKYPGI
                     ILFTSHDTRFVKHVSDKKWELTGQSLHDIT"
                     /name="ABC-F type ribosomal protection protein Msr(A)"
     gene            14474..15151
                     /locus_tag="DQV89_15070"
     CDS             14474..15151
                     /locus_tag="DQV89_15070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001106057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="QFM60881.1"
                     /translation="MYELFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHH
                     STIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIW
                     LRKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYL
                     NNLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIM
                     LAS"
                     /name="IS6 family transposase"
     gene            15209..15586
                     /locus_tag="DQV89_15075"
                     /pseudo=""
     CDS             15209..15586
                     /locus_tag="DQV89_15075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866106.1"
                     /note="incomplete; partial on complete genome; missing
                     start; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding response regulator"
                     /name="DNA-binding response regulator"
     gene            15583..16464
                     /gene="nsaS"
                     /locus_tag="DQV89_15080"
                     /pseudo=""
     CDS             15583..16464
                     /gene="nsaS"
                     /locus_tag="DQV89_15080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012656189.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /name="nsaS"
     gene            16589..17509
                     /locus_tag="DQV89_15085"
     CDS             16589..17509
                     /locus_tag="DQV89_15085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="QFM60882.1"
                     /translation="MNNIIEINNLTKQYGSQIAVNNLSITVESGQIYGFLGRNGAGKTT
                     TIRMLLGLIKPTKGNIKIFEKEFESNKTEILKNIGAMVETPGFYSNLTAKENLTINAKI
                     LGIQKENAIEEVLEIVGLASEKVKLFKNYSLGMKQRLGIARALLHNPELLILDEPTNGL
                     DPIGIKEIRKLIKDLAQSRNITILISSHILSEIEQLVDKVGIIHNGVLLEEIMYEDLKK
                     KNRQFISISVSDEEKVACLLETNFGIYDYKIKENGEFKIYSHIDRQQEINRLLVLNNID
                     VFQMRVIEDNLETYFEDLVGGGTIG"
                     /name="ABC transporter ATP-binding protein"
     gene            17502..18239
                     /locus_tag="DQV89_15090"
     CDS             17502..18239
                     /locus_tag="DQV89_15090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000369394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="QFM60883.1"
                     /translation="MDNLLRTEFIKLKRSYMFLISILGTCVAPFMVVVASFISMRTKVP
                     TPNIVFKQLFEEVSLYHMLIIGPPLYGVIIAYLFGREYIEDTLKNLLIIPISRESFLVS
                     KIILLFLWIQTLSVIAWLLTLMLGMLLHFQGLSQSLIIDSFFTFVIGGVLLWILSPPII
                     ILSIYFKNYVPTIVLTIIITLINLMTANSEHRGLFPWAAVGDISRGTLPNTYPFLLSLI
                     IIIVTSIFSVIILFSYFKKTDIS"
                     /name="ABC transporter permease"
     gene            18253..18456
                     /locus_tag="DQV89_15095"
     CDS             18253..18456
                     /locus_tag="DQV89_15095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001627151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP kinase"
                     /protein_id="QFM60884.1"
                     /translation="MGFIEQIKAFILGVVEGLTEFAPVSSTGHMIIVDDMWLNTADDLG
                     SASATTFKVVIQLGGSVAKLNL"
                     /name="UDP kinase"
     gene            18486..19160
                     /locus_tag="DQV89_15100"
     CDS             18486..19160
                     /locus_tag="DQV89_15100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="QFM60885.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            19301..19936
                     /locus_tag="DQV89_15105"
                     /pseudo=""
     CDS             19301..19936
                     /locus_tag="DQV89_15105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="internal stop; incomplete; partial on complete
                     genome; missing start; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside adenylyltransferase"
                     /name="aminoglycoside adenylyltransferase"
     gene            19933..20463
                     /gene="sat4"
                     /locus_tag="DQV89_15110"
     ARG             19934..20460
                     /name="sat4"
                     /gene="sat4"
                     /gene_name="streptothricin N-acetyltransferase Sat4"
                     /tool="amrfinderplus"
                     /drug_class="STREPTOTHRICIN"
                     /identity="97.78"
                     /coverage="100.0"
     gene            20556..21350
                     /gene="aph(3')-IIIa"
                     /locus_tag="DQV89_15115"
     ARG             20557..21347
                     /name="aph(3')-IIIa"
                     /gene="aph(3')-IIIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(21458..21646)
                     /locus_tag="DQV89_15120"
                     /pseudo=""
     CDS             complement(21458..21646)
                     /locus_tag="DQV89_15120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913594.1"
                     /note="incomplete; partial on complete genome; missing
                     start; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            21626..22084
                     /locus_tag="DQV89_15125"
                     /pseudo=""
     CDS             21626..22084
                     /locus_tag="DQV89_15125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_003446809.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /name="transcriptional regulator"
     gene            21982..22197
                     /locus_tag="DQV89_15130"
     CDS             21982..22197
                     /locus_tag="DQV89_15130"
                     /inference="COORDINATES: protein motif:HMM:PF13280.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="QFM60888.1"
                     /translation="MENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPASGGQ
                     EPESRMIEPISLGFYEQNWYLIGFAG"
                     /name="WYL domain-containing protein"
     gene            complement(22366..23040)
                     /locus_tag="DQV89_15135"
     CDS             complement(22366..23040)
                     /locus_tag="DQV89_15135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="QFM60889.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(23710..24288)
                     /locus_tag="DQV89_15140"
     CDS             complement(23710..24288)
                     /locus_tag="DQV89_15140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="QFM60890.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEAKENKNK"
                     /name="HTH domain-containing protein"
     gene            complement(24552..24932)
                     /gene="blaI"
                     /locus_tag="DQV89_15145"
     ARG             complement(24556..24932)
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="98.41"
                     /coverage="100.0"
     gene            complement(24922..26679)
                     /locus_tag="DQV89_15150"
     CDS             complement(24922..26679)
                     /locus_tag="DQV89_15150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactam sensor/signal transducer BlaR1"
                     /protein_id="QFM60892.1"
                     /translation="MAKLLIMSVVSFCFIFLLLVFFRYILKRYFNYSLNYKVWYLTMLA
                     GLIPFIPIKFSFIKFNNVNNQAPTVESKSHDLNHNINTTKPIQEFTTDIHKFNWDSIDN
                     ICTVIWIVLVIILSFKFLKALLYLKYLKKQSLYLNENEKNKIDTILFNHQYKKNIVIRK
                     AEAIQSPITFWYGKYIILIPSSYFKSVIDKRLKYIILHEYAHAKNRDTLHLIIFNIFSI
                     IMSYNPLVHIVKRKIIHDNEVEADRFVLNNINKNEFKTYAESIMDSVLKTPFSNKNILS
                     HSFNGKKSLLKSRLINIKEADLKKQSKLILIFICIFTFFIMIIQSQFLMGQSLTDYNYK
                     KPLQSDYQILDESKNFGSNSGSFVMYSMKKDKYYIYNEKESRKRYSPDSTYKIYLALFG
                     LDRHIISDKNSRMSWNHKHYLFESWNKEQDLNTAMQNSVNWYFERISNQIPKNYTAAQL
                     KQLNYGNENLGSYKSYWMEDSLKISNLEQVIVFKNMMEQNNHFSKKAKNQLSSSLLIKK
                     NEKYELYGKTGTGIVNGKYNNGWFVGYVITNHDKYYFATHLSDGNPSGKNAELISEKIL
                     KGMGVLNDQ"
                     /name="beta-lactam sensor/signal transducer BlaR1"
     gene            26786..27631
                     /locus_tag="DQV89_15155"
     CDS             26786..27631
                     /locus_tag="DQV89_15155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /protein_id="QFM60893.1"
                     /translation="MKKLIFLIVIALVLSACNSNSSHAKELNDLEKKYNAHIGVYALNT
                     KSGKEVKFNSDKRFAYASTSKAINSAILLEQVPYNKLNKKVHINKDDIVAYSPILEKYV
                     GKDITLKELIEASMTYSDNTANNKIIKEIGGIKKVKQRLKELGDKVTNPVRYEIELNYY
                     SPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKNFLLDLMFNNKNGDTLIKDGVPKDYKV
                     ADKSGQAITYASRNDVAFVYPKGQSEPIVLVIFTNKDNKSDKPNDKLISETAKSVMKEF
                     "
                     /name="penicillin-hydrolyzing class A beta-lactamase BlaZ"
     gene            27840..27935
                     /locus_tag="DQV89_15160"
                     /pseudo=""
     CDS             27840..27935
                     /locus_tag="DQV89_15160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001560862.1"
                     /note="incomplete; partial on complete genome; missing
                     stop; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase domain-containing protein"
                     /name="O-antigen ligase domain-containing protein"
     gene            complement(28157..28576)
                     /locus_tag="DQV89_15165"
     CDS             complement(28157..28576)
                     /locus_tag="DQV89_15165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="QFM60894.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     ARG             complement(7928..9468)
                     /name="qacB"
                     /gene="qacB"
                     /gene_name="quaternary ammonium compound efflux MFS
                     transporter QacB"
                     /tool="amrfinderplus"
                     /drug_class="QUATERNARY AMMONIUM"
                     /identity="99.42"
                     /coverage="100.0"
     ARG             9646..10208
                     /name="qacR"
                     /gene="qacR"
                     /gene_name="multidrug-binding transcriptional regulator
                     QacR"
                     /tool="amrfinderplus"
                     /drug_class="QUATERNARY AMMONIUM"
                     /identity="99.47"
                     /coverage="100.0"
     ARG             complement(12517..13979)
                     /name="msr(A)"
                     /gene="msr(A)"
                     /gene_name="ABC-F type ribosomal protection protein Msr(A)"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(24926..26679)
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.38"
                     /coverage="100.0"
     ARG             26787..27628
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(793..1406)
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(12514..13979)
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="98.36"
                     /coverage="100.0"
     ARG             complement(11516..12414)
                     /name="mphC"
                     /gene="mphC"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="98.66"
                     /coverage="100.0"
     ARG             19946..20463
                     /name="SAT-4"
                     /gene="SAT-4"
                     /gene_name="streptothricin acetyltransferase (SAT)"
                     /tool="rgi"
                     /drug_class="nucleoside antibiotic"
                     /identity="97.16"
                     /coverage="95.56"
     ARG             19338..19639
                     /name="aad(6)"
                     /gene="aad(6)"
                     /gene_name="ANT(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="99.0"
                     /coverage="36.23"
     ARG             26787..27631
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     Typing          complement(4179..4326)
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          complement(4385..4560)
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="92.697"
                     /coverage="94.0"
                     /evalue="1.04e-65"
     Typing          complement(4692..5674)
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.593"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          6101..6843
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 aagtgtgagt attcattaat acatttacta ttaattcaat cattttgcat ttctctacta
       61 accagtgtta taatttatat aacgaaaatg attaacaatt aatgcaccaa tccccacact
      121 attgcagtag tgtggggatt ttttcgatgc tggcttataa agtcgcctat taattatttg
      181 ttgcgtttac taagccaata agtataatac gcaacagcac agccactgat gactggtgct
      241 atgatgtgaa cgaaaatgat tagcaaagta atgcacctcc tctcttcgtc aattgacgcc
      301 tgagagatag gcgactctat tattatacca tctgtgaata tacaagcata tctacttccg
      361 ataagtcgtc ttatgttata taactttgtt ttttatagta tcaagacaag aagaaactcg
      421 tttcaaaaac cctcatgatt tttagagaaa aactctctta tttcatcgtc tttaataaaa
      481 taatatgcca tctttccatc tttataaaaa tcaagtacct catttttata taaaagcctt
      541 aaatgatgtg aagttgaagc aacactcatt ttcaatatca aagaaatatc acaaacacac
      601 aactcatctt ctttaatcaa agataatatg attttcaatt tcttctcatc acaaattttt
      661 tctaaaatgt taagtaattt cttagattta tcatcttcta aaaaacttaa agcattgtta
      721 actttatcct catgtacaca gatcacatca caagtatttt cataactcat ataaaatcac
      781 accctaaatt aaaatataaa tcctaaaatt gtttgaatag tgtcattttc aataataata
      841 aataaaccta aagctatata aataatagcc ataatccaac gactaaattt ctcaacaatt
      901 tctccaattc ctggaatatt agctaatttt tgtgcagtaa acaccaagaa gaaaattaaa
      961 attaaaaaga caaacagagt aagtaataaa ttagtaacac ttaatgtcac aaaatacgga
     1021 acaaataaac caatattatc ggcgccacaa cttgctatcg taacaattgc aaccgtacca
     1081 actaatttag acaatccttt ttcattcaat tcttttttag ctctcttttc tccttcacaa
     1141 tcatcataaa tagccacttt aattccaaga taaattggta ttaaacccaa taaacctaat
     1201 atccactttt ctggaacata atttaataca aaagctaaaa acaaactaac taatattaaa
     1261 ataatagacc ctaaatattg accaacataa atatctctat attcttttct agtctttgct
     1321 ctagcaaaaa atattaataa aattactaat aaatcaactg ctgtagcaat ataaagaaca
     1381 gcagcagcaa caaccgtttg aatcataata cacctcattc aaaaatattt ttgaatgtat
     1441 tataacttat atttttaaat aatcataggt gctttattcc aattgcttta ttgacgttga
     1501 gcctcggaac ccttaacaat cccaaaactt gtcgaatggt cggcttaata gctcacgcta
     1561 tgccgacatt cgtctgcaag tttagttaag ggttcttctc aacatcaata aattttttcg
     1621 gcataaatgc gtgtctatgc gtagacatgg agacacttca gaattatgga gtgattacat
     1681 gagtttaact atttttcttt attcagtttt aggaagttta ttagcaaatt atatctacga
     1741 aaaatcttca aaataaataa ctttttcggt tctactttgt acactttatc tacctggtag
     1801 acctaattgt tattgcttta caggtctaaa attcgtcgtt ataatctagt taaatcccgt
     1861 aagggcgcac ttatacgtcg gataaatcga catgtgcaaa aacgtaatcg accttcgtcg
     1921 atttttttat ttcaaaatta aagaaacggc ttgagatatt ccgagcagtt ataaaaatta
     1981 atttgcgttg aatattgcta ctacattctt gaaaaagtga tgtagattta tagcccataa
     2041 cttttttgaa ttacatcgac gatacggcgt cgaaagaaaa ataaatagac cgtatgaaag
     2101 aaaaagctac ctcactttat ctggggtagc ttttattttt tatgccctta ttttgaattt
     2161 taagagggca ttttaaagat ttaggggtga ttcatatagt tttatatcta aaacttatat
     2221 atgcttttaa aacgcaaata tgagccaaat aaatatatgc tattttcaaa aacaaaaatt
     2281 tgagcaaaaa caataactat ttttagacac tgcccattta catgcaaatt aaaaattagc
     2341 ataaaattct ttaaaacttc cccacgtttt tctaaattcc tgtagggcgt ttttatcaaa
     2401 aatcaagaca agaagaaact cgttcacact cgtttcaaaa aaacaagaaa tctaatctat
     2461 acacctaccg ttttccaacc ccctcaaagc atacaaatta aaaacaaaat tattcataat
     2521 cttactttct tttaacaaaa acataaaaac cataaataga caaattaact atcaaaggca
     2581 ataaacagta taaaaaaacc acgaataaat cttcatcaac atctaaaata aaaaagaata
     2641 aaacaattaa caaaatacta attaacaaac ctaaaagtgg caaacttttt atatattttt
     2701 ctaaattttc attcataaaa tagactcctt tcaaaaatat gtttataaat atattaaaat
     2761 aaatattgat tttataaagc gcttacttat acaattaaaa tatcttatta tcttggaggt
     2821 atcaaatgaa aattataaaa ttattttcaa taatttcctt gttcctactg gtatttagcg
     2881 cgaatttttc taatgcttac gcaaatgaag aacaaaaaag ttctttacta gaaaatcaaa
     2941 aagaaaaatt gaaaagcaaa aacatcgaag tatcacaaat gaccaagaaa gaaataagtt
     3001 ttctagaaca attgcaaaat aaaaatgaag atatgcaaaa attcgaaaag caaatgaaaa
     3061 aagaaggatt taaaaaaata aagctagaag acaaaaattc taaattaaaa tatctagcta
     3121 cagaagcaaa tgataaaaat gcatatggct acatagctaa taacgcttat aaaaatgaaa
     3181 aaacaaaaga aattgtagtt tctgaaacaa tatatgataa ctacaacaaa aaaatcacaa
     3241 aattcattgc cgaaaaaaga agtatgactg aaaacaaaga gggaaaaata cttattaaca
     3301 aaaattacgt tgaatataag gctgaaaaag ttgataaaaa cagaccggta acatatgcag
     3361 gattcaaatg gaacggcaaa gcattcgctt gtagtatggc tggactttat gcatgtgctc
     3421 actactgtgg agtatgggca atcgtaaatc caatagccgg cggtgtatgt gaagcagttt
     3481 gcggaactgc atttgcagct ggatgctctg taggttgatt ttattccaat tgttttattg
     3541 acgttgagcc tcggaaccct taacaatccc aaaacttgtc gaatggtcgg cttaatagct
     3601 cacgctatgc cgacattcgt ctgcaagttt agttaagggt tcttctcaac atcaataaat
     3661 tttttcggca taaatacgat gttccttatt tatcctcata aaaaacaata gctgaaatat
     3721 ataaccaatt actgtgtgtt tgaatttcta atacatgaat atcattcttt aaaaacctat
     3781 taacttgttt atctaattga cgatgagtaa aagtagcgaa agttttaatc ttcatgatat
     3841 ctctcctttt ataaaaatag caatccttat tacaatatta aacactttta ttttggattt
     3901 taagaggcat tttgaagact tagaggcaaa tcatataggt tttgtactta aaaatctata
     3961 cagtctctta aaacgcaaat atgagccaaa taaatatatg ctaatttcac aaacaaaaat
     4021 ttcagcaaaa tcagtgacta attttttaga tactgcccat ttacatgcaa atttaaaaat
     4081 tagcataaaa tactttaaaa cttccccatg tttttctaaa ttcctgcagg gcttttctta
     4141 tcaaaaactt agaaatttta atttaactct aaaatctccg taagagcata agggaaattt
     4201 gctatcattc aaaaatgata gatctggcaa ggccagacat tccaagggtt ttaagttatt
     4261 ttaaagtgat atcatacaaa gctgtagtgt cacacttttg tgacactaca tacagcattt
     4321 gtcacaaaaa taagacagca cttttttaca gaaaaacaat aaaaaaagac atcagttatc
     4381 actaatgtct taaataataa ttttgctttt cgaaattcca aattgcggta attgaatgtg
     4441 ctttttttct tcgtctgtcg ttttatcttc atcacttgta ttaatcaaat taccatcttc
     4501 ggcatcgtct aagtttaaaa ttttatgctt ttgtttaagc aatccaccat aacttaacat
     4561 acgttttcga tacaaacctt tttctaaatc acttacaatt tcttgatttt tttcgtcgtc
     4621 atcagttaaa aagtcagatg atttaacgga atattttgat gtctcttcga gtgttataaa
     4681 atcatttgaa ttattgatta aagatattat attgtttcat gtttttacgg cgcatataaa
     4741 gggcatgtgt ttcttcaagt tcagttagaa ttgtttgcat taaataagct tgcattgact
     4801 tgattgtttc cttttggcct ttaactcccc tatcatgtat agctttttta agtcttttta
     4861 aagaagttaa tatttcatcc tcaatgtcct ctaacatgta atgcatatct tcatgccttg
     4921 aattaaatga tttttttgct ttaagaataa cagcctttat gatttctaaa tctctataat
     4981 catattttaa taaataatta gttagttgtt ctgggaattc ttgcaatagc atttctttat
     5041 catcaaaatt atgtgtaaat tgatttgaat gatttgaatg attactaatt tcatttttgt
     5101 actttatatc attcaagtca ttcatatcat tattctcagt atcattaaag tcaatgtcat
     5161 taaagtcagt atcattagtg ttcgattttc gaacttctgg acgttcgatt ttcgaacttc
     5221 tggacgttcg attttcgaac ttctggacgt tcgattttcg aacttccttc tcgccgtaag
     5281 gttcaacatc gttttcttct ttttctattt tgtaaatatc acgttctgtg acaataggtt
     5341 tcattaaata tagaatattt ggtttattta aaccacgtcg tttttgaatg agtagaccat
     5401 cgttttctaa cccttttttt atttttgtta acttttcttt tttacaattt aagatttcca
     5461 ttagcttttc atttgaataa acaaagtaaa tgttaccatc ttcatcaacc cagctatttt
     5521 taatagataa atttaagcga tcacgtaaga tagcataggc tattttcata tcattagtta
     5581 gatttttata attttcactg gtaaagaata ctttagggat ttgataaaat ctttctttgt
     5641 aattttcttg cactgtaaaa tattgatttt gcatgacaaa aaacctcttt ccatatttta
     5701 gtttggtaag aggtaataaa acgtttttat ttagctttac atttatttaa tgatttaggt
     5761 gcttgcacta agatattatt cattatataa tacaagtatc gaaaattata taaataaaca
     5821 gtttctaaac gttttattac caaaccccga ctattaccag tagttggggt ttttgttata
     5881 ttaagtttat tatagcactt taaataaact tataaaaggg aaaatatagc tttatcaagg
     5941 gtttataaac ccttgataaa tatcataaac ctttcataaa cccttgataa aaaggttgat
     6001 ggatgtttat ttttatttat taatcacttt attattaagc attataagct tataatattt
     6061 tatcaagggt ttataaacat tttataaagg gttgatgata tgaaaagtgt gaaaaagttg
     6121 agtgaagaat taggggttag taagcaaacg atttttaata atattaagcg attgaatata
     6181 gagacaataa aacaggaaaa cacttcgttt attaaagaag ataccgatat agaaaaaatc
     6241 attcaaagag taaatgaaaa taaaaagaaa tatggttttg aaagtactac tgaagacaaa
     6301 caaaaaaaag ggtcggataa tattaatttt gaatcgaaaa gcgatgctca aatagtagaa
     6361 atccttaaaa atcagattga tactttaaat aatcaaattg aaaaacaaga aagtcgtcat
     6421 gaaacaacaa ttgaatttta cagaaaagag ttgcaagaaa gatcaaaatt gcttgaaaat
     6481 cagcaagttc tggcattaga gagtaataaa aagattcaaa aattagaaaa tcaattagaa
     6541 aaagaaaaac accttaatta tccctttgat acatctacta acactagaca aaacgttgat
     6601 gcacaagaaa aaacatatac tactaatcct gtaaatatta acagagatca ggaagaaact
     6661 aaagaaacag agattcaata taaggatata tctggaagtc aaagcgacga aagtacacaa
     6721 ggtgaagaag caaaaaaaga agacgttcca gctaatctaa atgacaatga tagtgatata
     6781 gaagaaaaga gtgaagaaac ggaacctaaa aaggggtttt ggagtcgttt gtttggtagc
     6841 taaaataatt gattaggcac taaaagttat aaaattttag tgtcttttat atagtgagaa
     6901 cttctggtaa tcatcagtta tgttaaactc taacaaaaac taaattatca gaagaattat
     6961 ctagggtatt aaacataggt aaatcaattt tctatcgcca atagtataaa catcatccat
     7021 attaatctga agatagctac ataattcttt aacagcatag cctttatttg tataaggcgc
     7081 cataaactct attaaatatg gtttgttttg aggtttctat gtttaatcat ttaatttttc
     7141 attatataaa tcgaataatt ataaaaagtc atcatacttt ttatttttta aaaatatttg
     7201 aaaatttaat agtaatccaa ttataagatc aaatatcatt atcattataa tcaaggcaac
     7261 tataatcact gtgacactcg ttacataaca agctagtaat ctccagataa aattgacatt
     7321 ttcaccaatt ccataactta acatattaca aagtagtaaa agaataataa tacctatact
     7381 gtaaattaaa attgtcagtg tatatttttt aataactcta ttaggaaaca atagttcatc
     7441 tattaggttc tttttcacca gtatctctcg ttcaattcta tctttgtcac agattttgat
     7501 tttactattt tttatttttt cctctaataa aataacctcg aacgatctgc taatttttaa
     7561 taaatatgca ggaaaagcta atgttaagca taatgtaatt aattcattta cattgttcat
     7621 gtaacttata aaatagatga aagttgctac tagtgctcct aaaaatatag ttatattaag
     7681 ttctacatca aatattttaa aaatatctgc tctattcatc agttaatcat cctttcaagg
     7741 tttattaata ctaataaatt attagatata ggtatatcat attattaatt taagaaattg
     7801 tcttttataa ttttacttaa taataaaaaa gtagaaccat ttaaaattaa tggttctact
     7861 ttttaactat tactaatttt aaaaataaac taatctacaa tatctaaaaa tatatgttta
     7921 gtactatttt tgtttagtta tatcaagtga tttgggaatt aacaaataga caactattga
     7981 aatgataatc atgataatcc cacctactaa agcagttgct acaaaagcat cattaaatga
     8041 tgttacagcc tcgtttgcaa gctgttttat ccccgtagct ttagctactt cgacagcgcc
     8101 cactacagat tcttcagcta catgagctaa atctccaact ataccttttg atgaaaaaga
     8161 tgaaatatct aaaaatacac gataaagcat agaagatagg ctaccaagta ctgctacacc
     8221 aaaaacattt ccaaggtcat acatagactc ttcaacagca gctgcattac ctgcttttga
     8281 tgtaggtgtt tctaacatta ttagagcaga tgcaactgct agtgaagccg taccagctcc
     8341 aactaaaatt aatgctaaag ccattgtaga atatgataat ggatgaccaa agaaatacat
     8401 aataaacatg ccaatggctg caattccaat tccggaaggt aacactattt tcggtccaaa
     8461 tcgcgccgct aatccgggtg caattggtgc aaacaccata tctcctattg ccataggtaa
     8521 taggtataag ccagctttaa aaggagaaag ttcttccaca acctgtaacc attgtgaagc
     8581 taataacaaa acagatgtca ttgcaaacat tgtcataaat gcagcaattg taccagctga
     8641 aaatgatctc tttttaaaaa gtcttacgtc taacattgga tcagaacttg ataaattacg
     8701 tttaacaaat atcactatca tggtaattgc taatactatt acaacccatg gaataatatc
     8761 tgctagtcct tcttttgaaa attctttgat actccatacc agtccaatca tgcctgcaat
     8821 tgataaaatt gtagaaggaa tatcccacga gtgagacttt tcttttgata acttagactc
     8881 tggtaataaa aataaacctg ctacaattgc tattatcaca aacggtacat taattaaaaa
     8941 tgccgagtgc catgaaaatt gctcaagtaa agctcctccg ataattggtc caaaaacagc
     9001 acctatcgat gaaacgattg accatacagc taatgcagtg gccctttctt tagggttttc
     9061 aaaaattact cttatcattg aaagagtagt tggcattatt aaagcacctg caataccaag
     9121 taaaaatcga atagctatta cgaactctgc actttctgcg aaaaatatag ctaatgaaac
     9181 gaggccaaat aaagcaaatc cagttaataa tgcttttttt cttccccatt tatcagcaaa
     9241 ggcactcaat ggaattataa agccagctaa aacaagagag tatatatcaa ctatccataa
     9301 ctgttgggta ccagaaggct ctaactctct tactaattcc ggtaaagcca taattaatat
     9361 tgtcatatcc attgtaacaa caaacaaact aacagctaat actactagtg cagtccatct
     9421 tttttttgat gtcatcatat cagtagtttt tgtaaaaaat gaaatcattt aagttccctc
     9481 caatccttat agaccgatcg atcggtctat aaggattata atctattttt ttacatatta
     9541 caacaaaaaa tcttgcgaaa tttaaatggc tgtattgtgt tatacaatta ttctttgaat
     9601 ttttgtgcta tcattgatag tacttaatac tcattaaagg cgtgatgaac ttgaaagata
     9661 aaatactagg tgtcgcaaag gaattattta taaaaaatgg atataatgcc actactactg
     9721 gagaaattgt taaattatca gaaagtagta aagggaatct ttattatcac tttaaaacaa
     9781 aagaaaatct atttttagaa attttaaata tagaagaatc taaatggcaa gaacagtgga
     9841 aaaaggaaca aatcaaatgt aaaactaata gagaaaaatt ttatttatat aatgaactat
     9901 ctttaacaac cgaatactat tatccacttc aaaacgcaat aattgaattt tgcactgaat
     9961 attataaaac taatagcatt aatgaaaaaa tgaataaatt agaaaacaaa tatatagatg
    10021 cttatcatgt aatttttaag gagggtaatt taaatggcga atggtgtatt aatgatgtta
    10081 atgctgttag taaaatagca gcaaacgctg ttaatggaat tgttaccttt acacatgaac
    10141 aaaatattaa tgaaagaatt aaacttatga acaagttctc tcaaattttt ttaaatggac
    10201 ttagtaaata attatatata tattcttgaa ataccaataa atattatttc taaattacgt
    10261 tcattattga taaaaaattt aaatagtatt actacacaaa aagagagtgc gaattcgcac
    10321 tctctttttt cttgtataat tattaaaaga tcatttcaat aatataatat gagttttgag
    10381 actctgtgag agcctcttat ttgcattgac gacccattta tcaagatgat cccttatcat
    10441 gcttaattct ataaactgtc tgtcttgtga tattaacttc tttcgcaatc ttactaattg
    10501 ctttcccttc ttctaacatt tccaccacgc gatgataaat aatacgtttc tgtgggtctt
    10561 tggcatttgg tgaataaagt aaggggcgcc ctttatatac gcctttttcc ttcgcaactt
    10621 gaattccttg cgcttgtcga cgtttacttt catttctctc ttgttctgaa accattgcta
    10681 aaatttgaac gattaaatct ttcataaact tatccagtaa tggattgcca atcacttcat
    10741 tcatcatagg taagctggta atcattaact gaacgtcttt ctcttttaaa taactcacag
    10801 tttcaataat ttcatcataa tcacgtccca aacgatcaat agattccaca acgaatcgat
    10861 ctcccattct gacaaaattg agtgcttctt gaaatacagg tctattttcc actgactttc
    10921 ccgactgttt ctctgtaaag attttctcca caccaaacgt ctttaaatta tccaattgtc
    10981 tttctaaatt ttgatctatc gatgatactc tcgcataacc tataatcatt catcttcact
    11041 ccataattaa tatacaccct aatcatacgt tctaattgcg ataatttcaa caacttattt
    11101 tgtatgatta gggtgtactc aaagtgtaca tatctataat taaaacttac taaaaataaa
    11161 tatagatttt ttctttgtaa cagaaccgtt catttgaagg tcatctctat cataaatatt
    11221 taaattaact aaaaatttta atcatctgtt taatacttat gaaatgtatt tacggtaggt
    11281 attaaaattg atgaaattta tataagtgct ttcaatgaaa atgaccgttt atttatcctc
    11341 ctgatttaag gagttagaaa tttcgaaaac gattctttcc atttgttgca tttgttccat
    11401 gtccagatat ttaatacatt atagaaaacc aaagaccatc actaattaaa cgcagtttta
    11461 aaatttcatc aggattgcct tcgtctttaa aatgggcctc ttttaatata agttctactc
    11521 tttcatacct aactctttca atgccatcgt ttcatacgcc gattctcctg attccatagc
    11581 aaactcagcg ataaacattg ggaatactgc attgagttct attatatgct ctttcattcg
    11641 tggccatatt tcacctccag ctttaccgta tgctgttata agttgctcta atccttcgtc
    11701 gtcgaataca cgatggtgtc ctataaagtc cattgatggg tcggagtggg ttgcttcagt
    11761 ccagtctatg agacctgtga cgtttgcttg gttatctacc attatatgtc ctggatgtaa
    11821 gtccccatgt atcatggtcg catgtcgagg ccatagttcg tcgttttcta accattgttt
    11881 ccatctgttc cataattcat ctgatacgcc ataagtttct ttaactttat tcattcttct
    11941 ttgaaagtca ttttttattt cttgtatggt tttgatattt atatgctgaa cgttaatgtt
    12001 ttcttctggt atgttgtgta aatctacgag tgtttcagct aatgtgttaa taaagttttc
    12061 tggtaatggt ttgtgttcaa tttcccatac ataattttgt atttctggat ctattgtggc
    12121 tgcgggttta cctgtaagtt ttgggtaagc aataaggtct tttgcatgta ctttccactt
    12181 cggtatttca aatgaaacat tcttctgtaa gaagtctacc gtttgttttt cgggttttgt
    12241 tcgtttataa acgtcaggtc ttcttggtag tctcaaaacc cattctactc catgtttatc
    12301 ttttccaaat gcaacttgaa aatcaagtcc cgattcattc aatgagattg tttgaggttg
    12361 gatgtgtaat tgatattttt ctgcacattt aataatttca ttatgtcgag tcattttatt
    12421 ggatccttat ttctattata tttttcttgt gaacgtattt tttatattga tataaatgaa
    12481 cctaatattc aatataaatt agtgtatagt ttttaagtta tatcatgaag agattgtcct
    12541 gttaattccc attttttatc tgatacatgt ttaacaaacc ttgtatcatg tgatgtaaac
    12601 aaaatgattc caggatattt attcataaac atttctaatg cttctaatgt tttaatatct
    12661 aaaaaattag ttggttcatc caaaattaac atattcgctt tcgttgaaaa taatactgct
    12721 aacgataatt tcgttctttc cccaccactc aaaacattac aagaacgatc aagtgcttca
    12781 tttaaaccca agttatttaa aatagctcta ctgaatgatt ctgatgaatc cgtttcatcc
    12841 attaaatatt gcaataatga aacgtcacgc atgtcttcat aagcaagttg acgatagtat
    12901 gccatttgca ctttaggaga acaatcaatt ccctctattt ggtggtaaat agcttcaagt
    12961 aaagttgtct tacctacacc atttgcacct acgagcgcta tatttttgcc atatggtatt
    13021 tggaatcgta cttgtgttag cagtttttga cttcctttaa ccaatgttag attttgtgca
    13081 atgattggat aattattatg gatatcataa attttatttt gtgggaaatt gaattcatga
    13141 taactttgtg gtttttcaac ttcttccaaa tgttccattc ttttttcaat atgcttagct
    13201 tgtttttgag cagccttctc aaccgtgcct ttttgttttg atgcacttaa acgatctggt
    13261 gctatacttt tgtttttttg ttttgatgat gcttgtgcca tttgttgcgc ttgatttcgt
    13321 ttagctttac tggcttggga caatctttgt ttttcactta tatactgttc atattgacgt
    13381 tgttgttcta actgttcttg ttcatattga ttttgatact gtgtgtaatt acctttaaac
    13441 actcttattg tgccatcttc ttgtatatcc caaattgtgt cagcaatttg gtctataagt
    13501 gctctatcat gacttactat aattaaagta ccatagtaat attttaaaat atttttcaga
    13561 taatctttac caattttatc caagtgattt gtaggttcat ctaaaagtaa tatcggacta
    13621 taatttgata tgacattagc taatttatat tttgcttttt caccaccact catactgtcg
    13681 gttgtatgca taggtatatg gagttcactc attaaactac cgtctaacgt gttaaaatca
    13741 ttttccacat ccatgttaag ctgttcaaaa tattgaattt cgccaaccgt ttcaactgtt
    13801 ccagattctg gttttgtttt ttgagcaatc atatttagta atgtggtttt gccagtacca
    13861 ttacccccaa taagtgctat tttttcaaat tggtaagcgt aaagatgacc gatgttaagt
    13921 gatcgtaaat ctgtcaattt atgattgatt tggttaaatt taattgtata ttgttccata
    13981 tttatacact ccttgtatat ttaaaggacg tgtacgcaaa aaaatgagac aggctactcc
    14041 cgtctcattc acattacact ttcaaacact taaaaattta ttatgatgtt ttagtatttg
    14101 aaagcgttta ttattcctat cgaaggataa aaaatgacat aagtcatcct atgagtgtgt
    14161 attgcggaca agcctttttg aattaattta gttttgtatt caaaaaggtt tatttgagtc
    14221 tcatagaagc tgtcatttta atcctccttc atcgataaaa tagtaatgtt aatataacat
    14281 tttgttggtt tttttacaat atatctctaa gtagaaagat tatataacaa aagtataaaa
    14341 atacaatttt agattgatta tacatctcct taatttagag tgtactcata aaatacggtt
    14401 ctgttgcaaa gttgaattta taatataatt taacaaaaag agtctctgta tgaactatca
    14461 ataaaatact gtactgtatg aactattcag atataaacaa tttaacaagg atgttatcac
    14521 tgtagccgtt ggctactatc taagatatgc attgagctat cgtgatatat ctgaaatatt
    14581 aagagaacgt ggtgtaaacg ttcatcattc aacgatctac cgttgggttc aagaatatgc
    14641 cccaatttta tatcaaattt ggaagaaaaa gcataaaaaa gcttattaca aatggcgtat
    14701 tgatgagacg tatatcaaaa taaaaggaaa atggagctat ttatatcgtg ccattgatac
    14761 agagggacat acattagata tttggttgcg taagcaacga gataatcatt cagcatatgc
    14821 gtttatcaaa cgtctcatta aacaatttgg taagcctcaa aaggtagtta cagatcaggc
    14881 accttcaacg aaggcagcaa tggctaaaat aattaaagct tttaaactta aacctgactg
    14941 tcattgtaca tcgaaatatc tgaataacct cattgagcaa gatcaccgtc atattaaagt
    15001 aagaaagaca agatatcaaa gtatcaatac ggcaaagaat actttaaaag gtattgaatg
    15061 tatttacgct ctatataaaa agaaccgtag gtctcttcag atctacggat tttccccatg
    15121 ccacgaaatt agcatcatgc tagcaagtta aacgaacact gacatgatat attagtgatt
    15181 agctatattt tttactttgc aacagaacca gccatttaat atgactgtta caattactaa
    15241 gattcaagca ctattacgcc gcacgtatga tttcaccact caagttaata atttaacagt
    15301 agatgattgc gagttactac ttgatgcagc aaagcttaaa tttaatgaag aaaccataga
    15361 cctgacacac actgaattgc aaatcatgca tagcttattc cagaacaagg gcaaattcgt
    15421 cagtcgtaat gcgttaatcg aaaaatgctg ggaatcagaa cacttcattg atgacaatac
    15481 gcttgctgtc aacattacac gtttacgcaa aaagctacaa aaactaggac ttacagattt
    15541 tatcgaaacg aagaaaaatg tcggatatcg tgtaggtgac gtatgaattt cttgaaatca
    15601 atccaacgtg aaatttatat tgtcatcctt acttgtgctt tattctactt tatattattc
    15661 atgtataatg tgccgatgca agcatatatg attggtctag gtattgtatt gtttgtttca
    15721 atgatttact ggggtatcca ttacatgaac tttaaaaaag aataaacact acaggaacag
    15781 aacgaagatt taagaatcga aaaccataaa cttcgtaatg actttattaa ctaccaaagt
    15841 gagttagagt catatttttt aatgtgggtg catcaaatca agacaccgat tacagcatca
    15901 aagttactgc ttgaagatcc tgatgaacac gtgatttcta acgtgcgtaa tgaagtctta
    15961 caaattgata attacacgaa tcttgcactg aactatttga aactcatgaa ccaaaagaca
    16021 tacatggtct ttatggaagt gagtgtagat gaattaattc gaccactgat taaacgttat
    16081 gcgatacagt ttattcatca tcaaacaaag ttgcattatg agaaaagtga agcggttata
    16141 ttaacagatg ccaaatgggc atcaattatg attgagcaaa tattaaacaa tgcattaaaa
    16201 tatgcacgtg gcaaagatgt gtggattacg tttgacgaaa atacaaagaa attatcaatc
    16261 cgagataacg gtatcggcat taatgcgagt gatttaccga aaatctttga taaaggtttc
    16321 tcgggctata acggtagaat aagtgagaaa tcaagcggta ttggtttata tattgtcagc
    16381 acaatctcaa agcgcttagg ccataaagta agtgctacat ctacattaaa cgatggttca
    16441 atattcacca ttcaatttaa ataactccaa tctttcattt ttgtaagatt agcggctgtt
    16501 tttgtaagaa tagataaagg cagccttttc taatcgcgcg taagataaag gtaacaacaa
    16561 actaagaaag gtgccagagg tgaaaaattt gaataatata attgaaataa ataacttaac
    16621 aaagcaatat ggaagtcaga tagcagttaa taatttgagt ataactgttg aaagtggaca
    16681 aatttatggt tttttaggaa gaaatggtgc aggcaaaaca actactataa gaatgctttt
    16741 aggcttaatt aaacctacga aaggtaatat taaaatattt gaaaaagagt tcgaaagtaa
    16801 taaaactgaa attttaaaaa atattggtgc tatggttgaa acgccaggtt tttatagtaa
    16861 tttgacagct aaagagaact taactataaa tgctaaaata ttaggtatac aaaaagaaaa
    16921 tgcaattgaa gaagtgttag aaatagtagg actagcttct gaaaaagtaa aattgtttaa
    16981 aaattattct ttaggtatga agcaacgttt agggattgcg agagctttat tgcacaatcc
    17041 cgaattattg atacttgatg agccgacgaa tggattagat cctattggca taaaagaaat
    17101 tagaaagttg attaaggatc tggctcaatc tagaaatata accattttaa tttcaagtca
    17161 tatattgtca gaaatagagc agttagtaga caaggtgggt attattcata acggagtttt
    17221 gttagaagaa attatgtatg aagatttaaa aaaaaagaac agacaattta taagtatatc
    17281 agtatcagat gaagaaaaag ttgcatgttt gttggaaact aacttcggaa tttatgacta
    17341 taaaattaaa gaaaatggcg aatttaaaat ttattcacat attgatagac aacaagaaat
    17401 taatagatta ttagtattaa acaatattga tgttttccag atgagagtga tagaagataa
    17461 tctagaaact tatttcgaag acttagtagg aggtggcaca attggataat ctactccgta
    17521 cagaatttat taagttaaaa agatcatata tgtttctaat aagtatttta ggtacatgcg
    17581 tagcaccttt tatggtggtt gtagcttctt ttattagtat gcggacgaaa gtaccgactc
    17641 ctaatattgt atttaaacag ttatttgaag aagtcagttt atatcatatg ctaattattg
    17701 gacctcctct atatggggtt ataatagcct atttgtttgg aagagaatat atagaagata
    17761 ctttaaaaaa cttattaatt atacctatat ctagagaaag ttttttagta agtaaaataa
    17821 tattattatt cttgtggatt caaacactat ctgttattgc atggttgcta actttaatgc
    17881 taggtatgct attgcatttt caagggttaa gccagagttt aataattgat tcattcttta
    17941 catttgttat tggcggagtg ttattatgga tattatctcc accaataatt attttgtcga
    18001 tatattttaa aaattatgtt cccacaattg ttttaaccat aataattact ttgataaatt
    18061 taatgactgc taattctgaa catagaggat tatttccttg ggctgcagtt ggagacatat
    18121 ctagaggaac attacctaat acttatccat ttctattatc tttaattatc ataattgtta
    18181 catctatatt cagtgtaatt atattattct catactttaa aaaaactgat ataagttaaa
    18241 aggaggagaa aaatgggttt tatagagcag attaaagcat ttattttagg tgtagttgaa
    18301 gggttgacag aatttgctcc agtatcatca acaggtcata tgattattgt tgatgatatg
    18361 tggttaaaca ctgctgacga tttaggaagt gcgtctgcaa ctacttttaa ggtggtaata
    18421 cagttaggag gttctgttgc aaagttgaat ttataatata attttaacaa aaaggagtct
    18481 tctgtatgaa ctatttcaga tataaacaat ttaacaagga tgttatcact gtagccgttg
    18541 gctactatct aagatatgca ttgagctatc gtgatatatc tgaaatatta agagaacgtg
    18601 gtgtaaacgt tcatcattca acgatctacc gttgggttca agaatatgcc ccaattttat
    18661 atcaaatttg gaagaaaaag cataaaaaag cttattacaa atggcgtatt gatgagacgt
    18721 atatcaaaat aaaaggaaaa tggagctatt tatatcgtgc cattgataca gagggacata
    18781 cattagatat ttggttgcgt aagcaacgag ataatcattc agcatatgcg tttatcaaac
    18841 gtctcattaa acaatttggt aaacctcaaa aggtaattac agatcaggca ccttcaacga
    18901 aggtagcaat ggttaaagta attaaagctt ttaaacttaa acctgactgc cattgtacat
    18961 cgaaatatct gaataacctc attgagcaag atcaccgtca tattaaagta agaaagacaa
    19021 ggtatcaaag tatcaataca gcaaagaata ctttaaaagg tattgagtgt atttacgctc
    19081 tatataaaaa gaaccgcagg tctcttcaga tctacggatt ttcgccatgc cacgaaatta
    19141 gcatcatgct agcaagttaa acgaacactg acatgatata ttagtgatta gctatatttt
    19201 ttactttgca acagaaccat catttttatt aaaatactct tttgtaaaat ctttctgctc
    19261 ttcaatgtat ttaatttctt tacctctaaa tctattatag ctatttgatg attacaataa
    19321 aattgatctt accttattgc ccttggaaga gttagataat tacctaaagg gcgataaatt
    19381 aataaaggtt ctaattgata aagattgtag aattaaaagg gacatagttc cgactgatat
    19441 agattatcat gtaagaaagc caagcgcaag ggagtatgat gattgctgca atgaattttg
    19501 gaatgtaaca ccttatgtta ttaaaggatt gtgccgtaag gaaattttat ttgctattga
    19561 tcattttaat cagattgttc gccatgagct gctgagaatg atatcatgga aggtcggcat
    19621 cgaaacaggc tttaaatgaa gtgtaggcaa gaactataag tttattgaaa ggtatatatc
    19681 cgaggatttg tgggagaaac ttttgtccac ctaccggatg gattcctatg aaaacatatg
    19741 ggaagcatta tttctatgcc atcaattgtt cagggcggta tccggtgagg tggcggaaag
    19801 gcttcattat gcctatccgg agtatgatag gaatataaca aaatatacca gggacatgta
    19861 taaaaaatac actggtaaaa ccggctgcct ggatagcaca tatgccgctg atatagaaga
    19921 gaggcgggaa cagtgattac agaaatgaaa gcagggcacc tgaaagatat cgataaaccc
    19981 agcgaaccat ttgaggtgat aggtaagatt ataccgaggt atgaaaacga gaattggacc
    20041 tttacagaat tactctatga agcgccatat ttaaaaagct accaagacga agaggatgaa
    20101 gaggatgagg aggcagattg ccttgaatat attgacaata ctgataagat aatatatctt
    20161 tactaccaag acgataaatg cgtcggaaaa gttaaactgc gaaaaaattg gaaccggtac
    20221 gcttatatag aagatatcgc cgtatgtaag gatttcaggg ggcaaggcat aggcagcgcg
    20281 cttatcaata tatctataga atgggcaaag cataaaaact tgcatggact aatgcttgaa
    20341 acccaggaca ataaccttat agcttgtaaa ttctatcata attgtggttt caaaatcggc
    20401 tccgtcgata ctatgttata cgccaacttt gaaaaagctg ttttctggta tttaaggttt
    20461 tagaatgcaa ggaacagtga attggagttc gtcttgttat aattagcttc ttggggtatc
    20521 tttaaatact gtagaaaaga ggaaggaaat aataaatggc taaaatgaga atatcaccgg
    20581 aattgaaaaa actgatcgaa aaataccgct gcgtaaaaga tacggaagga atgtctcctg
    20641 ctaaggtata taagctggtg ggagaaaatg aaaacctata tttaaaaatg acggacagcc
    20701 ggtataaagg gaccacctat gatgtggaac gggaaaagga catgatgcta tggctggaag
    20761 gaaagctgcc tgttccaaag gtcctgcact ttgaacggca tgatggctgg agcaatctgc
    20821 tcatgagtga ggccgatggc gtcctttgct cggaagagta tgaagatgaa caaagccctg
    20881 aaaagattat cgagctgtat gcggagtgca tcaggctctt tcactccatc gacatatcgg
    20941 attgtcccta tacgaatagc ttagacagcc gcttagccga attggattac ttactgaata
    21001 acgatctggc cgatgtggat tgcgaaaact gggaagaaga cactccattt aaagatccgc
    21061 gcgagctgta tgatttttta aagacggaaa agcccgaaga ggaacttgtc ttttcccacg
    21121 gcgacctggg agacagcaac atctttgtga aggatggcaa agtaagtggc tttattgatc
    21181 ttgggagaag cggcagggcg gacaagtggt atgacattgc cttctgcgtc cggtcgatca
    21241 gggaggatat cggggaagaa cagtatgtcg agctattttt tgacttactg gggatcaagc
    21301 ctgattggga gaaaataaaa tattatattt tactggatga attgttttag tacctagatt
    21361 tagatgtcta aaaagcttta actacaagct ttttagacat ctaatctttt ctgaagtaca
    21421 tccgcaactg tccatactct gatgttttat atcttttcta aaagttcgct agatagagtt
    21481 ctatattaga gatgtaaaga gttttggtga agaggtttgt gagtatggct tttataacca
    21541 gggtgcaatg agaagcacta acagcagcta gcttaagaac gcataggata tactttttat
    21601 ggaagtcaca gaggaggaat aaaatttgaa caggattaac agagtaacct ctattcttat
    21661 tcagctgcaa tcaaaaaaat aattcctgcc aaagaaattg cacagcgatt taatataagc
    21721 ttaaggacag tttacagaga tatccggaca cttgaagaag ccggaatacc aattggatct
    21781 gaggccggaa aaggatattt tcttgtagag ggcttcctac ttctgccggt aatgtttaca
    21841 gcggcggaag tgggtgcatt gattacagca gggaaatttt taaattgcca tggagatgaa
    21901 tcatttataa aggattttga ttcagctatg tataaaatca aatctatttt gaagcatggt
    21961 gaaaaaaact atgcacagga gttggagaac agtattaacg tgtacagcac atctggacag
    22021 aaaaatacat tggcggataa cgttattgca gcaattcaga ctgcaatctg caataaaagg
    22081 gtaatatcaa ttcaatatcc tgcatcagga gggcaagaac cggaaagcag aatgatagag
    22141 cctatatcac tggggtttta tgaacagaac tggtacttaa tcggttttgc aggctaagaa
    22201 atgaatatag gaattttcgt gtggatcgga ttaaaagcat ttgcatagaa gaagagctct
    22261 gtcaaagcca tgatggctct ttggaacaaa tattaaaaca aatgctggtt ctgttgcaaa
    22321 gtaaaaaaat atagctaacc actaatttat catgtcagtg ttcgcttaac ttgctagcat
    22381 gatgctaatt tcgtggcatg gcgaaaatcc gtagatctga agagacctgc ggttcttttt
    22441 atatagagcg taaatacact caataccttt taaagtattc tttgctgtat tgatactttg
    22501 ataccttgtc tttcttactt taatatgacg gtgatcttgc tcaatgaggt tattcagata
    22561 tttcgatgta caatggcagt caggtttaag tttaaaagct ttaattactt taaccattgc
    22621 taccttcgtt gaaggtgcct gatctgtaat taccttttga ggtttaccaa attgtttaat
    22681 gagacgtttg ataaacgcat atgctgaatg attatctcgt tgcttacgca accaaatatc
    22741 taatgtatgt ccctctgcat caatggcacg atataaatag ctccattttc cttttatttt
    22801 gatgtacgtc tcatcaatac gccatttgta ataagctttt ttatgctttt tcttccaaat
    22861 ttgatataaa attggggcat attcttgaac ccaacggtag accgttgaat gatgaacgtt
    22921 tacaccacgt tcccttaata tttcagatat atcacgataa ctcaatgcat atcttagata
    22981 gtagccaaca gctacagtga taacatcctt gttaaattgt ttatatctga aatagttcat
    23041 acagaagact cctttttgtt aaaattatac tataaattca actttgcaac agaacctcat
    23101 ttactatatg ggcatctctt tcattattaa tacaaagctt tgtatctccg atattaggca
    23161 aaggtgtaaa cgaattaggt gatactatag gattcaacat tatattaatc gtttctttaa
    23221 taatgattat cttcttattt tttataaatc gtagtaaaaa tatctcctat gattatataa
    23281 aagttcaaag aggtgaagcc aatgaataaa ttagaaaaat ggtctttggt atttattatt
    23341 tttacatttc tctcttcatt agcactttta tatttcaaat ataattttag ttcggttatg
    23401 ccagtcctaa gtctttctat tttaactata ctaatattgt tgacgagtat tattactgta
    23461 gtttcagtta atgatgaaga tacttaaaac gttcattagt gaaacaggta ttatattaaa
    23521 aaagcgtacg aatttgtacg cttttttctt gtgttattat taaaatctca taacaggaaa
    23581 atattatgag attttagacg ctgtcagaac gtctctttta catcgagtga cattgaatca
    23641 aagtctttgt atgttaatga tatataaaat tatttagtag attcattata gtaagctaga
    23701 ttagttgctc tacttgtttt tattctcttt tgcctctaat ttattgagat aacgataaat
    23761 agttgtacgt gaaacttgcc actgctctgc aattgtttta attggcgtac cattatcata
    23821 aagtgtctta agtaagttta aatcttgttt atttaatttt tcaggtctac ctccatatcg
    23881 gcctctagca cgtgctgcaa ttcgaccggc tgatgatcgc tctaaaatta aattacgttc
    23941 aaactctgca aatgctgcga ataaatgaaa taataattgt cctgtagaac ttgatttatc
    24001 catcgttata ttttcttcta aactatgaaa actcacacct cgttcgttaa gttcattaac
    24061 taacgtgatt aaatcctcca tgttccgtcc tagtctatct aatctccaaa caacaatcgt
    24121 atctcctgac ctcgcaaatt caattgcttt atctaaacca ggtcgcttac tttttgaacc
    24181 actcatatgg tcattaaata tcttttcaca accatatgta tttaatcgat cctcctgtaa
    24241 attcaaattt tgtaatccag ttgaaactct tgcataacct attttcaaaa tacagacctc
    24301 ctatatacac ctttagtgta ccataacttg attacgaggt cttttgtgaa catagatttt
    24361 ttgttgggtt tttgaacaca taattctatg taatacttac ttatttagac aaaaaacaag
    24421 agtgtacaga aaatggttat tttctggaca ctctcatctt taataatata ttttaaatgt
    24481 cattaacaaa actaatttaa taagagtcaa gtatggttta catatgtatt atgtttgaaa
    24541 catacctcta attacttttt actaatatca tttaaaatgt ctcgcaattc ttcaatttct
    24601 ttgttattta attcttcatt tttcgcaaaa ttcagcacta aacttttcat atcccctcca
    24661 tacagtttat taagaaaggt tttagcagtt ttcattttaa tatcgtcttc tttaatattt
    24721 gatgagtaaa aataaatatt ttctgatttg tatcgtttta taatctcttt tttatatagt
    24781 cttgtgatta atgttctaat cgttttatca ctaacttctt tatatttttg aatttcaact
    24841 acaatttcat tagctgatac tgatttttta tcccatatta tattcataac atcccattca
    24901 gccatagata tttcaacttg cttattggtc atttaaaaca cccattcctt ttaatatttt
    24961 ttcacttatt aattcagcat ttttcccaga cgggtttcca tctgataaat gtgtagcaaa
    25021 ataatactta tcatgatttg taattacgta acctacaaac cacccattat tatacttccc
    25081 gtttactata cctgtacctg ttttcccata cagttcatac ttttcatttt tcttaatcaa
    25141 taatgaagaa gataattgat tctttgcttt tttactaaaa tggttatttt gttccatcat
    25201 atttttaaaa actattactt gttcaagatt agatattttc aaactatctt ccatccaata
    25261 gcttttataa cttcccaaat tttcattacc ataatttaat tgcttgagtt gagccgcagt
    25321 atagttcttt ggtatttgat tactaatacg ttcgaagtac caattaactg aattttgcat
    25381 tgctgtattt aaatcttgtt ccttattcca agactcgaaa agataatgtt tatgattcca
    25441 tgacatacgt gaatttttat cacttataat atgacggtca agtccaaaca gtgctaaata
    25501 aattttgtaa gttgaatcag gagaatatct ttttctactt tctttttcat tataaatata
    25561 gtatttgtct ttcttcatgc tgtacataac gaaagatcca ctatttgaac caaaattttt
    25621 actttcatct aaaatttggt aatcgctttg taagggcttt ttataattat aatcagttaa
    25681 ggattgcccc attaaaaact ggctttgaat tatcatgata aaaaaagtaa aaatacaaat
    25741 aaaaattaga attaattttg actgcttttt cagatcggct tcttttatat taattaatct
    25801 acttttgagt aatgattttt taccattaaa tgaatggctt aatatatttt tgttggaaaa
    25861 tggggttttt aatacggagt ccataataga ttccgcataa gttttaaatt catttttgtt
    25921 aatattatta aggacaaatc tatcggcttc tacttcattg tcatgaatta tctttctttt
    25981 tacaatatgt actaatggat tgtaactcat aataatagag aagatattaa agataattaa
    26041 atgtaaagta tctctatttt tagcatgagc atattcatgc agtattatat attttagtct
    26101 tttatcaatt acacttttaa aatatgaact aggaatcaaa ataatatatt tcccatacca
    26161 aaaagttatt ggagattgaa tagcctctgc ttttcgaatc acaatatttt ttttatattg
    26221 atggttgaaa agtatcgtat ctattttatt tttttcattt tcgtttagat aaagtgactg
    26281 tttctttaaa tatttaagat ataataaggc tttcaaaaat ttaaaactta aaataataac
    26341 taaaactatc caaataactg tgcagatatt atcaattgaa tcccaattaa acttatggat
    26401 atctgttgtg aactcttgaa taggtttggt ggtatttatg ttatggttca aatcgtgtga
    26461 cttactttca actgtgggcg cttgattatt cacattatta aattttataa aagagaattt
    26521 aattgggata aaaggaatta atccagcaag catagttaga taccaaactt tataatttaa
    26581 actataatta aaatagcgtt ttaatatgta cctaaaaaat actaacaata gaaatataaa
    26641 acaaaagctt actacgctca ttattagtaa tttagccatt ttgacacctt ctttcaaata
    26701 tttataataa acaattgaca tcaatattac aattgtaata ttattgattt ataaaaatta
    26761 caactgtaat atcggagggt ttattttgaa aaagttaata tttttaattg taattgcttt
    26821 agttttaagt gcatgtaatt caaacagttc acatgccaaa gagttaaatg atttagaaaa
    26881 aaaatataat gctcatattg gtgtttatgc tttaaatact aaaagtggta aggaagtaaa
    26941 atttaattca gataagagat ttgcctatgc ttcgacttca aaagcgataa atagtgctat
    27001 tttgttagaa caagtacctt ataataagtt aaataaaaaa gtacatatta acaaagatga
    27061 tatagttgct tattctccta ttttagaaaa atatgtagga aaagatatca ctttaaaaga
    27121 acttattgag gcttcaatga catatagtga taatacagca aacaataaaa ttataaaaga
    27181 aatcggtgga atcaaaaaag ttaaacaacg tctaaaagaa ctaggagata aagtaacaaa
    27241 tccagttaga tatgagatag aattaaatta ctattcacca aagagcaaaa aagatacttc
    27301 aacgcctgct gctttcggca agactttaaa taaacttatc gcaaatggaa aattaagcaa
    27361 aaaaaataaa aatttcttac ttgatttaat gtttaataat aaaaacggag acactttaat
    27421 taaagatggt gttccaaaag actataaggt tgctgataaa agtggtcaag caataacata
    27481 tgcttctaga aatgatgttg cttttgttta tcctaagggc caatctgaac ctattgtttt
    27541 agtcattttt acgaataaag acaataaaag tgataagcca aatgataagt tgataagtga
    27601 aaccgccaag agtgtaatga aggaatttta atattctaaa tgcataataa atactgataa
    27661 catcttatag tttgtattat attttgtatt atcgttgaca tgtataattt tgatatcaaa
    27721 aactgatttt ccctttatta ttttcgagat ttattttctt aattctcttt aacaaactag
    27781 aaatattgta tatacaaaaa atcataaata atagatgaat agtttaatta taggtgttca
    27841 tcaatcgaaa aagcaacgta tcttatttaa agtgcgttgc ttttttctca tttataaggt
    27901 taaataattc tcatatatca agcaaagtga caatagcatt ttacaagtat tttttattgt
    27961 tcgattaggg taaacctaaa taatacataa attatattac aatatgttta ttatagaggc
    28021 taaagtatct tagaaatttg gatagtaggt ttttcgggaa taaaagtata gttggcttta
    28081 atatataatt aagctaagct atcatttata tttactcgat tataattcgc acttcaactt
    28141 ttttataacg taaaaattaa aacgtagttt tatttatctt tagtaatatc tttttaaaca
    28201 ctacagtttc ttcattagtt aaattagcga agtaatgatt attaagttga taggctttct
    28261 tttctaatgt tggccataag tcttttgctt tatttgtact gtttattagc acagttcttc
    28321 tattttcatt atcagtttga cgtgttatta gatccttttt ggacatctta tctaatattc
    28381 cagatattgt tgaaggttct aaatttaaag tattaccaat cgctttaggt gtattcaaat
    28441 tactattaat caagcaattc aaaacaccat attctgctgg agtaatatta tagggactta
    28501 ataaactttt aaaatgttta aaaactctat tctgagaagt actcaacaaa taatttatac
    28561 aattatctaa ttccacaact aaaacctctc ttaaatcatt agtattgact cgcttatcat
    28621 atcatgataa gttttgtagg aaaatagttt tgcaacaaaa acatacttct acaaaacaat
    28681 tgtgaaagaa ggctaataaa tgttcaatgc ggtagtagtg agaaaaagtg catcaaatgt
    28741 tagttataaa gtagaaaaag ttgatgaatc tcatttatcg aagggtgatg tattagtaaa
    28801 agtggtatac tcttcaataa attataagga tatgctagct ttacaatata aaggcggtgt
    28861 aattagagat tatcctatga ttcctggtat agattttgca ggtattgttg aatcaagttc
    28921 gaatgataag tttaaagaag gcgataatgt attagttact ggttatgatg ttggcgtgac
    28981 acatacaggt ggattttcag aatatgcaca agtgcctgga gagtggattg ttcctattcc
    29041 ccaagaaatg tctattaaag agtctatggt atatggcaca gccggtttta cggcagcatt
    29101 atcaattttt gaactagaaa aatatggaat gaatatcaaa tcacaacctg aaattttagt
    29161 gtctggggct acaggtggtg tgggcagtgt tgctatacaa attttacata aaattggata
    29221 tgaaaatatc actgctatcg taagaaaaga aaagcaaata gaaatcgcaa aaaaattagg
    29281 tgcaaaacaa gtaataataa ttgaagatga taataaaccg cttaaaaaag gtatttttga
    29341 ttatttctta gatacagtgg ggagtaatgt aacattatac ggtttaaaac gtctaaatta
    29401 tcaaggtgtt gctactgtat gtggaaatgt agcaggaaat tcacttaacg ctaatatatt
    29461 accgtttatt cttagaggta ttaaattaat tggcattgat tctgtatatg ttgatcataa
    29521 tatccgtgaa gatatatgga gtaagttagc aaatgaatgg aatataggaa attcacttct
    29581 atacaatgaa attggatttg aagaattcta taaaacgata gatcagcttt taaaaggaca
    29641 acatttagga agaactattt taaaagtat
//
