LOCUS       CP030616               19409 bp    DNA     circular BCT 10-OCT-2019
DEFINITION  Staphylococcus aureus strain ER01560.3 plasmid unnamed2, complete
            sequence.
ACCESSION   CP030616
VERSION     CP030616.1
DBLINK      BioProject: PRJNA470993
            BioSample: SAMN09483954
KEYWORDS    .
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 19409)
  AUTHORS   Sullivan,M.J., Altman,D.R., Chacko,K., Cliferri,B., Webster,E.,
            Deikus,G., Lewis,M., Khan,Z., Beckford,C., Rendo,A., Samaroo,F.,
            Sebra,R., Karam-Howlin,R., Southwick,K., Adams,E., Ying,L.,
            Kornblum,J., Factor,S., Danesh Yazdi,M., Dingle,T., Hamula,C.,
            Bashir,A., Schadt,E., Kasarskis,A., Patel,G., Wallach,F., Gibbs,K.
            and van Bakel,H.
  TITLE     Whole genome sequencing to identify and define MRSA outbreaks
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 19409)
  AUTHORS   Sullivan,M.J., Altman,D.R., Chacko,K., Cliferri,B., Webster,E.,
            Deikus,G., Lewis,M., Khan,Z., Beckford,C., Rendo,A., Samaroo,F.,
            Sebra,R., Karam-Howlin,R., Southwick,K., Adams,E., Ying,L.,
            Kornblum,J., Factor,S., Danesh Yazdi,M., Dingle,T., Hamula,C.,
            Bashir,A., Schadt,E., Kasarskis,A., Patel,G., Wallach,F., Gibbs,K.
            and van Bakel,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUN-2018) Genetics and Genomic Sciences, Icahn School
            of Medicine, One Gustave L. Levy Place Box 1498, New York, NY 10029,
            USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.2.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 269.614418227x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 06/29/2018 16:05:40
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            Annotation Method :: Best-placed reference protein set; GeneMarkS+
            Annotation Software revision      :: 4.5
            Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region
            Genes (total)                     :: 3,100
            CDS (total)                       :: 3,018
            Genes (coding)                    :: 2,930
            CDS (coding)                      :: 2,930
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 46 of 88
            Pseudo Genes (incomplete)         :: 39 of 88
            Pseudo Genes (internal stop)      :: 22 of 88
            Pseudo Genes (multiple problems)  :: 18 of 88
            ##Genome-Annotation-Data-END##
            Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..19409
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="ER01560.3"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="unnamed2"
                     /geo_loc_name="USA:New York City"
                     /lat_lon="40.7903114 N 73.9528738 W"
                     /collection_date="2015"
                     /collected_by="Mount Sinai Hospital"
     gene            complement(317..1009)
                     /locus_tag="DQU73_15390"
     CDS             complement(317..1009)
                     /locus_tag="DQU73_15390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QFM40596.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVE
                     YKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTA
                     FAAGCSVG"
                     /name="hypothetical protein"
     gene            1119..1313
                     /locus_tag="DQU73_15395"
     CDS             1119..1313
                     /locus_tag="DQU73_15395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QFM40597.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     gene            2429..3046
                     /locus_tag="DQU73_15400"
     CDS             2429..3046
                     /locus_tag="DQU73_15400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017465246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium transporter"
                     /protein_id="QFM40598.1"
                     /translation="MIQTVVAAAVLYIATAVDLLVILLIFFARAKTRKEYRDIYVGQYL
                     GSIILILVSLFLAFVLNYVPEKWILGLLGLIPIYLGIKVAIYDDCEGEKRAKKELNEKG
                     LSKLVGTVAIVTIASCGADNIGLFVPYFVTLSVTNLLLTLFVFLILIFFLVFTAQKLAN
                     IPGIGEIVEKFSRWIMAIIYIALGLFIIIENDTIQTILGFIF"
                     /name="cadmium transporter"
     gene            3065..3412
                     /locus_tag="DQU73_15405"
     CDS             3065..3412
                     /locus_tag="DQU73_15405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="QFM40599.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="transcriptional regulator"
     gene            3569..3661
                     /locus_tag="DQU73_15410"
     CDS             3569..3661
                     /locus_tag="DQU73_15410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="QFM40600.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(3833..4804)
                     /locus_tag="DQU73_15415"
     CDS             complement(3833..4804)
                     /locus_tag="DQU73_15415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH:quinone reductase"
                     /protein_id="QFM40601.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFEEFYKTIDQLLKGQHLGRTILKV"
                     /name="NADPH:quinone reductase"
     gene            4928..5347
                     /locus_tag="DQU73_15420"
     CDS             4928..5347
                     /locus_tag="DQU73_15420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="QFM40602.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            complement(5569..5664)
                     /locus_tag="DQU73_15425"
                     /pseudo=""
     CDS             complement(5569..5664)
                     /locus_tag="DQU73_15425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001560862.1"
                     /note="incomplete; partial on complete genome; missing
                     stop; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase domain-containing protein"
                     /name="O-antigen ligase domain-containing protein"
     gene            complement(5873..6718)
                     /locus_tag="DQU73_15430"
     CDS             complement(5873..6718)
                     /locus_tag="DQU73_15430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /protein_id="QFM40603.1"
                     /translation="MKKLIFLIVIALVLSACNSNSSHAKELNDLEKKYNAHIGVYALNT
                     KSGKEVKFNSDKRFAYASTSKAINSAILLEQVPYNKLNKKVHINKDDIVAYSPILEKYV
                     GKDITLKELIEASMTYSDNTANNKIIKEIGGIKKVKQRLKELGDKVTNPVRYEIELNYY
                     SPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKNFLLDLMFNNKNGDTLIKDGVPKDYKV
                     ADKSGQAITYASRNDVAFVYPKGQSEPIVLVIFTNKDNKSDKPNDKLISETAKSVMKEF
                     "
                     /name="penicillin-hydrolyzing class A beta-lactamase BlaZ"
     gene            6825..8582
                     /locus_tag="DQU73_15435"
     CDS             6825..8582
                     /locus_tag="DQU73_15435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactam sensor/signal transducer BlaR1"
                     /protein_id="QFM40604.1"
                     /translation="MAKLLIMSVVSFCFIFLLLVFFRYILKRYFNYSLNYKVWYLTMLA
                     GLIPFIPIKFSFIKFNNVNNQAPTVESKSHDLNHNINTTKPIQEFTTDIHKFNWDSIDN
                     ICTVIWIVLVIILSFKFLKALLYLKYLKKQSLYLNENEKNKIDTILFNHQYKKNIVIRK
                     AEAIQSPITFWYGKYIILIPSSYFKSVIDKRLKYIILHEYAHAKNRDTLHLIIFNIFSI
                     IMSYNPLVHIVKRKIIHDNEVEADRFVLNNINKNEFKTYAESIMDSVLKTPFSNKNILS
                     HSFNGKKSLLKSRLINIKEADLKKQSKLILIFICIFTFFIMIIQSQFLMGQSLTDYNYK
                     KPLQSDYQILDESKNFGSNSGSFVMYSMKKDKYYIYNEKESRKRYSPDSTYKIYLALFG
                     LDRHIISDKNSRMSWNHKHYLFESWNKEQDLNTAMQNSVNWYFERISNQIPKNYTAAQL
                     KQLNYGNENLGSYKSYWMEDSLKISNLEQVIVFKNMMEQNNHFSKKAKNQLSSSLLIKK
                     NEKYELYGKTGTGIVNGKYNNGWFVGYVITNHDKYYFATHLSDGNPSGKNAELISEKIL
                     KGMGVLNDQ"
                     /name="beta-lactam sensor/signal transducer BlaR1"
     gene            8572..8952
                     /gene="blaI"
                     /locus_tag="DQU73_15440"
     ARG             8573..8949
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="98.41"
                     /coverage="100.0"
     gene            9216..9794
                     /locus_tag="DQU73_15445"
     CDS             9216..9794
                     /locus_tag="DQU73_15445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="QFM40606.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEAKENKNK"
                     /name="HTH domain-containing protein"
     gene            complement(10017..10202)
                     /locus_tag="DQU73_15450"
     CDS             complement(10017..10202)
                     /locus_tag="DQU73_15450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QFM40607.1"
                     /translation="MNKLEKWSLVFIIFTFLSSLALLYFKYNFSSVMPVLSLSILTILI
                     LLTSIITVVSVNDEDT"
                     /name="hypothetical protein"
     gene            10464..11138
                     /locus_tag="DQU73_15455"
     CDS             10464..11138
                     /locus_tag="DQU73_15455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="QFM40608.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(11198..11368)
                     /locus_tag="DQU73_15460"
                     /pseudo=""
     CDS             complement(11198..11368)
                     /locus_tag="DQU73_15460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015063485.1"
                     /note="incomplete; partial on complete genome; missing
                     stop; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /name="IS6 family transposase"
     gene            11842..13308
                     /locus_tag="DQU73_15465"
     CDS             11842..13308
                     /locus_tag="DQU73_15465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002447408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(A)"
                     /protein_id="QFM40609.1"
                     /translation="MEQYTIKFNQINHKLTDLRSLNIGHLYAYQFEKIALIGGNGTGKT
                     TLLNMIAQKTKPESGTVETVGEIQYFEQLNMDVENDFNTLDGSLMSELHIPMHTTDSMS
                     GGEKAKYKLANVISNYSPILLLDEPTNHLDKIGKDYLKNILKYYYGTLIIVSHDRALID
                     QIADTIWDIQEDGTIRVFKGNYTQYQNQYEQEQLEQQRQYEQYISEKQRLSQASKAKRN
                     QAQQMAQASSKQKNKSIAPDRLSASKQKGTVEKAAQKQAKHIEKRMEHLEEVEKPQSYH
                     EFNFPQNKIYDIHNNYPIIAQNLTLVKGSQKLLTQVRFQIPYGKNIALVGANGVGKTTL
                     LEAIYHQIEGIDCSPKVQMAYYRQLAYEDMRDVSLLQYLMDETDSSESFSRAILNNLGL
                     NEALDRSCNVLSGGERTKLSLAVLFSTKANMLILDEPTNFLDIKTLEALEMFMNKYPGI
                     ILFTSHDTRFVKHVSDKKWELTGQSLHDIT"
                     /name="ABC-F type ribosomal protection protein Msr(A)"
     gene            13407..14306
                     /gene="mph(C)"
                     /locus_tag="DQU73_15470"
     ARG             13408..14303
                     /name="mph(C)"
                     /gene="mph(C)"
                     /gene_name="Mph(C) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            14792..15400
                     /locus_tag="DQU73_15475"
     CDS             14792..15400
                     /locus_tag="DQU73_15475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="QFM40611.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEIIETVNYLKEKDVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRV
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDKGLS"
                     /name="recombinase family protein"
     gene            15646..15984
                     /locus_tag="DQU73_15480"
     CDS             15646..15984
                     /locus_tag="DQU73_15480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QFM40612.1"
                     /translation="MNLIPFIIILIFSCLWTAITNKYLPSETLDKKGQQDRYDERQRKM
                     FIEILAKSFIWIVYCMLFTLVLKFTGLSPSIEGSWFSQYPEIFFIIVALFLMLFNYYTT
                     NKKYTSKG"
                     /name="hypothetical protein"
     gene            15989..16174
                     /locus_tag="DQU73_15485"
     CDS             15989..16174
                     /locus_tag="DQU73_15485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011276570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="QFM40613.1"
                     /translation="MKNRIREYRKQKGISQETLSKELKVSRQTINAIENNKYDPTLTLA
                     FKLARLFDTTVDELFS"
                     /name="transcriptional regulator"
     gene            complement(16401..17144)
                     /locus_tag="DQU73_15490"
     CDS             complement(16401..17144)
                     /locus_tag="DQU73_15490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002508633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="QFM40614.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     gene            17570..18553
                     /locus_tag="DQU73_15495"
     CDS             17570..18553
                     /locus_tag="DQU73_15495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="QFM40615.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNK
                     PNILYLMKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSKIERPEVRK
                     SNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNQFTHNFDDKEMLLQEFPE
                     QLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHD
                     RGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication protein"
     gene            18546..18862
                     /locus_tag="DQU73_15500"
                     /pseudo=""
     CDS             18546..18862
                     /locus_tag="DQU73_15500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002483623.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /name="replication protein"
     ARG             11843..13305
                     /name="msr(A)"
                     /gene="msr(A)"
                     /gene_name="ABC-F type ribosomal protection protein Msr(A)"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             6826..8579
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.38"
                     /coverage="100.0"
     ARG             complement(5877..6718)
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             2430..3043
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             11843..13308
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="98.36"
                     /coverage="100.0"
     ARG             13408..14306
                     /name="mphC"
                     /gene="mphC"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="98.66"
                     /coverage="100.0"
     ARG             complement(5874..6718)
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     Typing          18919..19066
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          complement(16402..17144)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          17571..18553
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.593"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          18685..18854
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.605"
                     /coverage="91.0"
                     /evalue="1.04e-65"
ORIGIN
        1 tgaagattaa aactttcgct acttttactc atcgtcaatt agataaacaa gttaataggt
       61 ttttaaagaa tgatattcat gtattagaaa ttcaaacaca cagtaattgg ttatatattt
      121 cagctattgt tttttatgag gataaataag gaacatcgta tttatgccga aaaaatttat
      181 tgatgttgag aagaaccctt aactaaactt gcagacgaat gtcggcatag cgtgagctat
      241 taagccgacc attcgacaag ttttgggatt gttaagggtt ccgaggctca acgtcaataa
      301 aacaattgga ataaaatcaa cctacagagc atccagctgc aaatgcagtt ccgcaaactg
      361 cttcacatac accgccggct attggattta cgattgccca tactccacag tagtgagcac
      421 atgcataaag tccagccata ctacaagcga atgctttgcc gttccatttg aatcctgcat
      481 atgttaccgg tctgttttta tcaacttttt cagccttata ttcaacgtaa tttttgttaa
      541 taagtatttt tccctctttg ttttcagtca tacttctttt ttcggcaatg aattttgtga
      601 tttttttgtt gtagttatca tatattgttt cagaaactac aatttctttt gttttttcat
      661 ttttataagc gttattagct atgtagccat atgcattttt atcatttgct tctgtagcta
      721 gatattttaa tttagaattt ttgtcttcta gctttatttt tttaaatcct tcttttttca
      781 tttgcttttc gaatttttgc atatcttcat ttttattttg caattgttct agaaaactta
      841 tttctttctt ggtcatttgt gatacttcga tgtttttgct tttcaatttt tctttttgat
      901 tttctagtaa agaacttttt tgttcttcat ttgcgtaagc attagaaaaa ttcgcgctaa
      961 ataccagtag gaacaaggaa attattgaaa ataattttat aattttcatt tgatacctcc
     1021 aagataataa gatattttaa ttgtataagt aagcgcttta taaaatcaat atttatttta
     1081 atatatttat aaacatattt ttgaaaggag tctattttat gaatgaaaat ttagaaaaat
     1141 atataaaaag tttgccactt ttaggtttgt taattagtat tttgttaatt gttttattct
     1201 tttttatttt agatgttgat gaagatttat tcgtggtttt tttatactgt ttattgcctt
     1261 tgatagttaa tttgtctatt tatggttttt atgtttttgt taaaagaaag taagattatg
     1321 aataattttg tttttaattt gtatgctttg agggggttgg aaaacggtag gtgtatagat
     1381 tagatttctt gtttttttga aacgagtgtg aacgagtttc ttcttgtctt gatttttgat
     1441 aaaaacgccc tacaggaatt tagaaaaacg tggggaagtt ttaaagaatt ttatgctaat
     1501 ttttaatttg catgtaaatg ggcagtgtct aaaaatagtt attgtttttg ctcaaatttt
     1561 tgtttttgaa aatagcatat atttatttgg ctcatatttg cgttttaaaa gcatatataa
     1621 gttttagata taaaactata tgaatcaccc ctaaatcttt aaaatgccct cttaaaattc
     1681 aaaataaggg cataaaaaat aaaagctacc ccagataaag tgaggtagct ttttctttca
     1741 tacggtctat ttatttttct ttcgacgccg tatcgtcgat gtaattcaaa aaagttatgg
     1801 gctataaatc tacatcactt tttcaagaat gtagtagcaa tattcaacgc aaattaattt
     1861 ttataactgc tcggaatatc tcaagccgtt tctttaattt tgaaataaaa aaatcgacga
     1921 aggtcgatta cgtttttgca catgtcgatt tatccgacgt ataagtgcgc ccttacggga
     1981 tttaactaga ttataacgac gaattttaga cctgtaaagc aataacaatt aggtctacca
     2041 ggtagataaa gtgtacaaag tagaaccgaa aaagttattt attttgaaga tttttcgtag
     2101 atataatttg ctaataaact tcctaaaact gaataaagaa aaatagttaa actcatgtaa
     2161 tcactccata attctgaagt gtctccatgt ctacgcatag acacgcattt atgccgaaaa
     2221 aatttattga tgttgagaag aacccttaac taaacttgca gacgaatgtc ggcatagcgt
     2281 gagctattaa gccgaccatt cgacaagttt tgggattgtt aagggttccg aggctcaacg
     2341 tcaataaagc aattggaata aagcacctat gattatttaa aaatataagt tataatacat
     2401 tcaaaaatat ttttgaatga ggtgtattat gattcaaacg gttgttgctg ctgctgttct
     2461 ttatattgct acagcagttg atttattagt aattttatta atattttttg ctagagcaaa
     2521 gactagaaaa gaatatagag atatttatgt tggtcaatat ttagggtcta ttattttaat
     2581 attagttagt ttgtttttag cttttgtatt aaattatgtt ccagaaaagt ggatattagg
     2641 tttattgggt ttaataccaa tttatcttgg aattaaagtg gctatttatg atgattgtga
     2701 aggagaaaag agagctaaaa aagaattgaa tgaaaaagga ttgtctaaat tagttggtac
     2761 ggttgcaatt gttacgatag caagttgtgg cgccgataat attggtttat ttgttccgta
     2821 ttttgtgaca ttaagtgtta ctaatttatt acttactctg tttgtctttt taattttaat
     2881 tttcttcttg gtgtttactg cacaaaaatt agctaatatt ccaggaattg gagaaattgt
     2941 tgagaaattt agtcgttgga ttatggctat tatttatata gctttaggtt tatttattat
     3001 tattgaaaat gacactattc aaacaatttt aggatttata ttttaattta gggtgtgatt
     3061 ttatatgagt tatgaaaata cttgtgatgt gatctgtgta catgaggata aagttaacaa
     3121 tgctttaagt tttttagaag atgataaatc taagaaatta cttaacattt tagaaaaaat
     3181 ttgtgatgag aagaaattga aaatcatatt atctttgatt aaagaagatg agttgtgtgt
     3241 ttgtgatatt tctttgatat tgaaaatgag tgttgcttca acttcacatc atttaaggct
     3301 tttatataaa aatgaggtac ttgattttta taaagatgga aagatggcat attattttat
     3361 taaagacgat gaaataagag agtttttctc taaaaatcat gagggttttt gaaacgagtt
     3421 tcttcttgtc ttgatactat aaaaaacaaa gttatataac ataagacgac ttatcggaag
     3481 tagatatgct tgtatattca cagatggtat aataatagag tcgcctatct ctcaggcgtc
     3541 aattgacgaa gagaggaggt gcattacttt gctaatcatt ttcgttcaca tcatagcacc
     3601 agtcatcagt ggctgtgctg ttgcgtatta tacttattgg cttagtaaac gcaacaaata
     3661 attaataggc gactttataa gccagcatcg aaaaaatccc cacactactg caatagtgtg
     3721 gggattggtg cattaattgt taatcatttt cgttatataa attataacac tggttagtag
     3781 agaaatgcaa aatgattgaa ttaatagtaa atgtattaat gaatactcac acttatactt
     3841 ttaaaatagt tcttcctaaa tgttgtcctt ttaaaagctg atctatcgtt ttatagaatt
     3901 cttcaaatcc aatttcattg tatagaagtg aatttcctat attccattca tttgctaact
     3961 tactccatat atcttcacgg atattatgat caacatatac agaatcaatg ccaattaatt
     4021 taatacctct aagaataaac ggtaatatat tagcgttaag tgaatttcct gctacatttc
     4081 cacatacagt agcaacacct tgataattta gacgttttaa accgtataat gttacattac
     4141 tccccactgt atctaagaaa taatcaaaaa tacctttttt aagcggttta ttatcatctt
     4201 caattattat tacttgtttt gcacctaatt tttttgcgat ttctatttgc ttttcttttc
     4261 ttacgatagc agtgatattt tcatatccaa ttttatgtaa aatttgtata gcaacactgc
     4321 ccacaccacc tgtagcccca gacactaaaa tttcaggttg tgatttgata ttcattccat
     4381 atttttctag ttcaaaaatt gataatgctg ccgtaaaacc ggctgtgcca tataccatag
     4441 actctttaat agacatttct tggggaatag gaacaatcca ctctccaggc acttgtgcat
     4501 attctgaaaa tccacctgta tgtgtcacgc caacatcata accagtaact aatacattat
     4561 cgccttcttt aaacttatca ttcgaacttg attcaacaat acctgcaaaa tctataccag
     4621 gaatcatagg ataatctcta attacaccgc ctttatattg taaagctagc atatccttat
     4681 aatttattga agagtatacc acttttacta atacatcacc cttcgataaa tgagattcat
     4741 caactttttc tactttataa ctaacatttg atgcactttt tctcactact accgcattga
     4801 acatttatta gccttctttc acaattgttt tgtagaagta tgtttttgtt gcaaaactat
     4861 tttcctacaa aacttatcat gatatgataa gcgagtcaat actaatgatt taagagaggt
     4921 tttagttgtg gaattagata attgtataaa ttatttgttg agtacttctc agaatagagt
     4981 ttttaaacat tttaaaagtt tattaagtcc ctataatatt actccagcag aatatggtgt
     5041 tttgaattgc ttgattaata gtaatttgaa tacacctaaa gcgattggta atactttaaa
     5101 tttagaacct tcaacaatat ctggaatatt agataagatg tccaaaaagg atctaataac
     5161 acgtcaaact gataatgaaa atagaagaac tgtgctaata aacagtacaa ataaagcaaa
     5221 agacttatgg ccaacattag aaaagaaagc ctatcaactt aataatcatt acttcgctaa
     5281 tttaactaat gaagaaactg tagtgtttaa aaagatatta ctaaagataa ataaaactac
     5341 gttttaattt ttacgttata aaaaagttga agtgcgaatt ataatcgagt aaatataaat
     5401 gatagcttag cttaattata tattaaagcc aactatactt ttattcccga aaaacctact
     5461 atccaaattt ctaagatact ttagcctcta taataaacat attgtaatat aatttatgta
     5521 ttatttaggt ttaccctaat cgaacaataa aaaatacttg taaaatgcta ttgtcacttt
     5581 gcttgatata tgagaattat ttaaccttat aaatgagaaa aaagcaacgc actttaaata
     5641 agatacgttg ctttttcgat tgatgaacac ctataattaa actattcatc tattatttat
     5701 gattttttgt atatacaata tttctagttt gttaaagaga attaagaaaa taaatctcga
     5761 aaataataaa gggaaaatca gtttttgata tcaaaattat acatgtcaac gataatacaa
     5821 aatataatac aaactataag atgttatcag tatttattat gcatttagaa tattaaaatt
     5881 ccttcattac actcttggcg gtttcactta tcaacttatc atttggctta tcacttttat
     5941 tgtctttatt cgtaaaaatg actaaaacaa taggttcaga ttggccctta ggataaacaa
     6001 aagcaacatc atttctagaa gcatatgtta ttgcttgacc acttttatca gcaaccttat
     6061 agtcttttgg aacaccatct ttaattaaag tgtctccgtt tttattatta aacattaaat
     6121 caagtaagaa atttttattt tttttgctta attttccatt tgcgataagt ttatttaaag
     6181 tcttgccgaa agcagcaggc gttgaagtat cttttttgct ctttggtgaa tagtaattta
     6241 attctatctc atatctaact ggatttgtta ctttatctcc tagttctttt agacgttgtt
     6301 taactttttt gattccaccg atttctttta taattttatt gtttgctgta ttatcactat
     6361 atgtcattga agcctcaata agttctttta aagtgatatc ttttcctaca tatttttcta
     6421 aaataggaga ataagcaact atatcatctt tgttaatatg tactttttta tttaacttat
     6481 tataaggtac ttgttctaac aaaatagcac tatttatcgc ttttgaagtc gaagcatagg
     6541 caaatctctt atctgaatta aattttactt ccttaccact tttagtattt aaagcataaa
     6601 caccaatatg agcattatat tttttttcta aatcatttaa ctctttggca tgtgaactgt
     6661 ttgaattaca tgcacttaaa actaaagcaa ttacaattaa aaatattaac tttttcaaaa
     6721 taaaccctcc gatattacag ttgtaatttt tataaatcaa taatattaca attgtaatat
     6781 tgatgtcaat tgtttattat aaatatttga aagaaggtgt caaaatggct aaattactaa
     6841 taatgagcgt agtaagcttt tgttttatat ttctattgtt agtatttttt aggtacatat
     6901 taaaacgcta ttttaattat agtttaaatt ataaagtttg gtatctaact atgcttgctg
     6961 gattaattcc ttttatccca attaaattct cttttataaa atttaataat gtgaataatc
     7021 aagcgcccac agttgaaagt aagtcacacg atttgaacca taacataaat accaccaaac
     7081 ctattcaaga gttcacaaca gatatccata agtttaattg ggattcaatt gataatatct
     7141 gcacagttat ttggatagtt ttagttatta ttttaagttt taaatttttg aaagccttat
     7201 tatatcttaa atatttaaag aaacagtcac tttatctaaa cgaaaatgaa aaaaataaaa
     7261 tagatacgat acttttcaac catcaatata aaaaaaatat tgtgattcga aaagcagagg
     7321 ctattcaatc tccaataact ttttggtatg ggaaatatat tattttgatt cctagttcat
     7381 attttaaaag tgtaattgat aaaagactaa aatatataat actgcatgaa tatgctcatg
     7441 ctaaaaatag agatacttta catttaatta tctttaatat cttctctatt attatgagtt
     7501 acaatccatt agtacatatt gtaaaaagaa agataattca tgacaatgaa gtagaagccg
     7561 atagatttgt ccttaataat attaacaaaa atgaatttaa aacttatgcg gaatctatta
     7621 tggactccgt attaaaaacc ccattttcca acaaaaatat attaagccat tcatttaatg
     7681 gtaaaaaatc attactcaaa agtagattaa ttaatataaa agaagccgat ctgaaaaagc
     7741 agtcaaaatt aattctaatt tttatttgta tttttacttt ttttatcatg ataattcaaa
     7801 gccagttttt aatggggcaa tccttaactg attataatta taaaaagccc ttacaaagcg
     7861 attaccaaat tttagatgaa agtaaaaatt ttggttcaaa tagtggatct ttcgttatgt
     7921 acagcatgaa gaaagacaaa tactatattt ataatgaaaa agaaagtaga aaaagatatt
     7981 ctcctgattc aacttacaaa atttatttag cactgtttgg acttgaccgt catattataa
     8041 gtgataaaaa ttcacgtatg tcatggaatc ataaacatta tcttttcgag tcttggaata
     8101 aggaacaaga tttaaataca gcaatgcaaa attcagttaa ttggtacttc gaacgtatta
     8161 gtaatcaaat accaaagaac tatactgcgg ctcaactcaa gcaattaaat tatggtaatg
     8221 aaaatttggg aagttataaa agctattgga tggaagatag tttgaaaata tctaatcttg
     8281 aacaagtaat agtttttaaa aatatgatgg aacaaaataa ccattttagt aaaaaagcaa
     8341 agaatcaatt atcttcttca ttattgatta agaaaaatga aaagtatgaa ctgtatggga
     8401 aaacaggtac aggtatagta aacgggaagt ataataatgg gtggtttgta ggttacgtaa
     8461 ttacaaatca tgataagtat tattttgcta cacatttatc agatggaaac ccgtctggga
     8521 aaaatgctga attaataagt gaaaaaatat taaaaggaat gggtgtttta aatgaccaat
     8581 aagcaagttg aaatatctat ggctgaatgg gatgttatga atataatatg ggataaaaaa
     8641 tcagtatcag ctaatgaaat tgtagttgaa attcaaaaat ataaagaagt tagtgataaa
     8701 acgattagaa cattaatcac aagactatat aaaaaagaga ttataaaacg atacaaatca
     8761 gaaaatattt atttttactc atcaaatatt aaagaagacg atattaaaat gaaaactgct
     8821 aaaacctttc ttaataaact gtatggaggg gatatgaaaa gtttagtgct gaattttgcg
     8881 aaaaatgaag aattaaataa caaagaaatt gaagaattgc gagacatttt aaatgatatt
     8941 agtaaaaagt aattagaggt atgtttcaaa cataatacat atgtaaacca tacttgactc
     9001 ttattaaatt agttttgtta atgacattta aaatatatta ttaaagatga gagtgtccag
     9061 aaaataacca ttttctgtac actcttgttt tttgtctaaa taagtaagta ttacatagaa
     9121 ttatgtgttc aaaaacccaa caaaaaatct atgttcacaa aagacctcgt aatcaagtta
     9181 tggtacacta aaggtgtata taggaggtct gtattttgaa aataggttat gcaagagttt
     9241 caactggatt acaaaatttg aatttacagg aggatcgatt aaatacatat ggttgtgaaa
     9301 agatatttaa tgaccatatg agtggttcaa aaagtaagcg acctggttta gataaagcaa
     9361 ttgaatttgc gaggtcagga gatacgattg ttgtttggag attagataga ctaggacgga
     9421 acatggagga tttaatcacg ttagttaatg aacttaacga acgaggtgtg agttttcata
     9481 gtttagaaga aaatataacg atggataaat caagttctac aggacaatta ttatttcatt
     9541 tattcgcagc atttgcagag tttgaacgta atttaatttt agagcgatca tcagccggtc
     9601 gaattgcagc acgtgctaga ggccgatatg gaggtagacc tgaaaaatta aataaacaag
     9661 atttaaactt acttaagaca ctttatgata atggtacgcc aattaaaaca attgcagagc
     9721 agtggcaagt ttcacgtaca actatttatc gttatctcaa taaattagag gcaaaagaga
     9781 ataaaaacaa gtagagcaac taatctagct tactataatg aatctactaa ataattttat
     9841 atatcattaa catacaaaga ctttgattca atgtcactcg atgtaaaaga gacgttctga
     9901 cagcgtctaa aatctcataa tattttcctg ttatgagatt ttaataataa cacaagaaaa
     9961 aagcgtacaa attcgtacgc ttttttaata taatacctgt ttcactaatg aacgttttaa
    10021 gtatcttcat cattaactga aactacagta ataatactcg tcaacaatat tagtatagtt
    10081 aaaatagaaa gacttaggac tggcataacc gaactaaaat tatatttgaa atataaaagt
    10141 gctaatgaag agagaaatgt aaaaataata aataccaaag accatttttc taatttattc
    10201 attggcttca cctctttgaa cttttatata atcataggag atatttttac tacgatttat
    10261 aaaaaataag aagataatca ttattaaaga aacgattaat ataatgttga atcctatagt
    10321 atcacctaat tcgtttacac ctttgcctaa tatcggagat acaaagcttt gtattaataa
    10381 tgaaagagat gcccatatag taaatgaggt tctgttgcaa agttgaattt atagtataat
    10441 tttaacaaaa aggagtcttc tgtatgaact atttcagata taaacaattt aacaaggatg
    10501 ttatcactgt agctgttggc tactatctaa gatatgcatt gagttatcgt gatatatctg
    10561 aaatattaag ggaacgtggt gtaaacgttc atcattcaac ggtctaccgt tgggttcaag
    10621 aatatgcccc aattttatat caaatttgga agaaaaagca taaaaaagct tattacaaat
    10681 ggcgtattga tgagacgtac atcaaaataa aaggaaaatg gagctattta tatcgtgcca
    10741 ttgatgcaga gggacataca ttagatattt ggttgcgtaa gcaacgagat aatcattcag
    10801 catatgcgtt tatcaaacgt ctcattaaac aatttggtaa acctcaaaag gtaattacag
    10861 atcaggcacc ttcaacgaag gtagcaatgg ttaaagtaat taaagctttt aaacttaaac
    10921 ctgactgcca ttgtacatcg aaatatctga ataacctcat tgagcaagat caccgtcata
    10981 ttaaagtaag aaagacaagg tatcaaagta tcaatacagc aaagaatact ttaaaaggta
    11041 ttgagtgtat ttacgctcta tataaaaaga accgcaggtc tcttcagatc tacggatttt
    11101 cgccatgcca cgaaattagc atcatgctag caagttaagc gaacactgac atgataaatt
    11161 agtggttagc tatatttttt tactttgcaa cagaaccaat tggggcatat tcttgaaccc
    11221 aacggtagat cgttgaatga tgaacgttta caccacgttc tcttaatatt tcagatatat
    11281 cacgatagct caatgcatat cttagatagt agccaacggc tacagtgata acatccttgt
    11341 taaattgttt atatctgaaa tagttcatac agaagactcc tttttgttaa aattatatta
    11401 taaattcaac tttgcaacag aaccgtattt tatgagtaca ctctaaatta aggagatgta
    11461 taatcaatct aaaattgtat ttttatactt ttgttatata atctttctac ttagagatat
    11521 attgtaaaaa aaccaacaaa atgttatatt aacattacta ttttatcgat gaaggaggat
    11581 taaaatgaca gcttctatga gactcaaata aacctttttg aatacaaaac taaattaatt
    11641 caaaaaggct tgtccgcaat acacactcat aggatgactt atgtcatttt ttatccttcg
    11701 ataggaataa taaacgcttt caaatactaa aacatcataa taaattttta agtgtttgaa
    11761 agtgtaatgt gaatgagacg ggagtagcct gtctcatttt tttgcgtaca cgtcctttaa
    11821 atatacaagg agtgtataaa tatggaacaa tatacaatta aatttaacca aatcaatcat
    11881 aaattgacag atttacgatc acttaacatc ggtcatcttt acgcttacca atttgaaaaa
    11941 atagcactta ttgggggtaa tggtactggc aaaaccacat tactaaatat gattgctcaa
    12001 aaaacaaaac cagaatctgg aacagttgaa acggttggcg aaattcaata ttttgaacag
    12061 cttaacatgg atgtggaaaa tgattttaac acgttagacg gtagtttaat gagtgaactc
    12121 catataccta tgcatacaac cgacagtatg agtggtggtg aaaaagcaaa atataaatta
    12181 gctaatgtca tatcaaatta tagtccgata ttacttttag atgaacctac aaatcacttg
    12241 gataaaattg gtaaagatta tctgaaaaat attttaaaat attactatgg tactttaatt
    12301 atagtaagtc atgatagagc acttatagac caaattgctg acacaatttg ggatatacaa
    12361 gaagatggca caataagagt gtttaaaggt aattacacac agtatcaaaa tcaatatgaa
    12421 caagaacagt tagaacaaca acgtcaatat gaacagtata taagtgaaaa acaaagattg
    12481 tcccaagcca gtaaagctaa acgaaatcaa gcgcaacaaa tggcacaagc atcatcaaaa
    12541 caaaaaaaca aaagtatagc accagatcgt ttaagtgcat caaaacaaaa aggcacggtt
    12601 gagaaggctg ctcaaaaaca agctaagcat attgaaaaaa gaatggaaca tttggaagaa
    12661 gttgaaaaac cacaaagtta tcatgaattc aatttcccac aaaataaaat ttatgatatc
    12721 cataataatt atccaatcat tgcacaaaat ctaacattgg ttaaaggaag tcaaaaactg
    12781 ctaacacaag tacgattcca aataccatat ggcaaaaata tagcgctcgt aggtgcaaat
    12841 ggtgtaggta agacaacttt acttgaagct atttaccacc aaatagaggg aattgattgt
    12901 tctcctaaag tgcaaatggc atactatcgt caacttgctt atgaagacat gcgtgacgtt
    12961 tcattattgc aatatttaat ggatgaaacg gattcatcag aatcattcag tagagctatt
    13021 ttaaataact tgggtttaaa tgaagcactt gatcgttctt gtaatgtttt gagtggtggg
    13081 gaaagaacga aattatcgtt agcagtatta ttttcaacga aagcgaatat gttaattttg
    13141 gatgaaccaa ctaatttttt agatattaaa acattagaag cattagaaat gtttatgaat
    13201 aaatatcctg gaatcatttt gtttacatca catgatacaa ggtttgttaa acatgtatca
    13261 gataaaaaat gggaattaac aggacaatct cttcatgata taacttaaaa actatacact
    13321 aatttatatt gaatattagg ttcatttata tcaatataaa aaatacgttc acaagaaaaa
    13381 tataatagaa ataaggatcc aataaaatga ctcgacataa tgaaattatt aaatgtgcag
    13441 aaaaatatca attacacatc caacctcaaa caatctcatt gaatgaatcg ggacttgatt
    13501 ttcaagttgc atttggaaaa gataaacatg gagtagaatg ggttttgaga ctaccaagaa
    13561 gacctgacgt ttataaacga acaaaacccg aaaaacaaac ggtagacttc ttacagaaga
    13621 atgtttcatt tgaaataccg aagtggaaag tacatgcaaa agaccttatt gcttacccaa
    13681 aacttacagg taaacccgca gccacaatag atccagaaat acaaaattat gtatgggaaa
    13741 ttgaacacaa accattacca gaaaacttta ttaacacatt agctgaaaca ctcgtagatt
    13801 tacacaacat accagaagaa aacattaacg ttcagcatat aaatatcaaa accatacaag
    13861 aaataaaaaa tgactttcaa agaagaatga ataaagttaa agaaacttat ggcgtatcag
    13921 atgaattatg gaacagatgg aaacaatggt tagaaaacga cgaactatgg cctcgacatg
    13981 cgaccatgat acatggggac ttacatccag gacatataat ggtagataac caagcaaacg
    14041 tcacaggtct catagactgg actgaagcaa cccactccga cccatcaatg gactttatag
    14101 gacaccatcg tgtattcgac gacgaaggat tagagcaact tataacagca tacggtaaag
    14161 ctggaggtga aatatggcca cgaatgaaag agcatataat agaactcaat gcagtattcc
    14221 caatgtttat cgctgagttt gctatggaat caggagaatc ggcgtatgaa acgatggcat
    14281 tgaaagagtt aggtatgaaa gagtagaact tatattaaaa gaggcccatt ttaaagacga
    14341 aggcaatcct gatgaaattt taaaactgcg tttaattagt gatggtcttt ggttttctat
    14401 aatgtattaa atatctggac atggaacaaa tgcaacaaat ggaaagaatc gttttcgaaa
    14461 tttctaactc cttaaatcag gaggataaat aaacggtcat tttcattgaa agcacttata
    14521 taaatttcat caattttaat acctaccgta aatacatttc ataagtatta aacagatgat
    14581 taaaattttt agttaattta aatatttatg atagagatga ccttcaaatg aacggttctg
    14641 ttacaaagaa aaaatctata tttattttta gtaagtttta attatagata tgtacacttt
    14701 gagtacaccc taaccataca aaaagaattg ttgaaattat aacaattaaa acgtatgatt
    14761 agggtgtata tttattatgg agtgaagatg aatgattata ggttatgcga gagtatcatc
    14821 gatagatcaa aatttagaaa gacaattgga taatttaaag acgtttggtg tggagaaaat
    14881 ctttacagag aaacagtcgg gaaagtcagt ggaaaataga cctgtatttc aagaagcact
    14941 caattttgtc agaatgggag atcgattcgt tgtggaatct attgatcgtt taggacgtaa
    15001 ctatgatgaa attattgaaa ctgtgaatta tttaaaagaa aaagacgttc agttaatgat
    15061 taccagctta cctatgatga atgaagtaat tggcaatcca ttactggata agtttatgaa
    15121 agatttaatc attcaaatat tagcaatggt ttcagaacaa gagagaaatg aaagtaaacg
    15181 tcgacaagcg caagggattc aagttgcgaa ggaaaaaggc gtatataaag ggcgcccttt
    15241 actttattca ccaaatgcta aagacccaca gaaacgtgtt atttatcatc gcgtggtgga
    15301 aatgttagaa gaaggcaaag cgattagtaa gattgcgaaa gaagttaata tcacaagaca
    15361 aacagtttat agaattaaac atgataaggg attatcttga taaattgatt gtcaatgcaa
    15421 atgagcgtct ctcacagtgt ctcaaattcc ataacatatt attgaattga gattttaata
    15481 attatacaag aaaaaagagt acgagttcgc agctttctat atagtaattg ttttactaat
    15541 aaggtgtttt aaaatatatt ataatgtaaa aagtatttga catttgtatc aaaaatattt
    15601 acactcataa atgtcaaata ctttttacat ttatgaggtg ttataatgaa tttaattcct
    15661 tttattatta ttttaatttt ttcttgttta tggacggcta taactaacaa atatttacct
    15721 tcagaaacat tagataaaaa aggacaacaa gatcgatacg atgaaagaca acgtaaaatg
    15781 tttattgaaa tactggctaa aagttttatt tggattgtat attgtatgtt atttacacta
    15841 gtgcttaaat ttacaggttt gtcaccaagt attgaaggat cttggttttc tcaatatcca
    15901 gaaattttct ttataattgt agcactattt cttatgctgt ttaattacta tactacaaat
    15961 aaaaaatata catctaaagg ttaaattaat gaaaaataga attagagaat atagaaaaca
    16021 aaaaggaatt tctcaagaaa ctttaagtaa agaattaaaa gtgtctaggc aaactattaa
    16081 tgcaatagaa aacaataaat atgatcctac attgacatta gcatttaagt tggcaagatt
    16141 gtttgataca actgtggatg aattattttc ttaaccattc atttatcaca aaaagagagt
    16201 gcgaattcgc actctctttt tgtgtagtag tactattaaa ttttgtctca ataacgaacg
    16261 tttataacgc aatcatgatg agagtattaa tacagttaat tatttgaaat actttagttt
    16321 acataatcga tgattaccag aagttctcac tatataaaag acactaaaat tttataactt
    16381 ttagtgccta atcaattatt ttagctacca aacaaacgac tccaaaaccc ctttttaggt
    16441 tccgtttctt cactcttttc ttctatatca ctatcattgt catttagatt agctggaacg
    16501 tcttcttttt ttgcttcttc accttgtgta ctttcgtcgc tttgacttcc agatatatcc
    16561 ttatattgaa tctctgtttc tttagtttct tcctgatctc tgttaatatt tacaggatta
    16621 gtagtatatg ttttttcttg tgcatcaacg ttttgtctag tgttagtaga tgtatcaaag
    16681 ggataattaa ggtgtttttc tttttctaat tgattttcta atttttgaat ctttttatta
    16741 ctctctaatg ccagaacttg ctgattttca agcaattttg atctttcttg caactctttt
    16801 ctgtaaaatt caattgttgt ttcatgacga ctttcttgtt tttcaatttg attatttaaa
    16861 gtatcaatct gatttttaag gatttctact atttgagcat cgcttttcga ttcaaaatta
    16921 atattatccg accctttttt ttgtttgtct tcagtagtac tttcaaaacc atatttcttt
    16981 ttattttcat ttactctttg aatgattttt tctatatcgg tatcttcttt aataaacgaa
    17041 gtgttttcct gttttattgt ctctatattc aatcgcttaa tattattaaa aatcgtttgc
    17101 ttactaaccc ctaattcttc actcaacttt ttcacacttt tcatatcatc aaccctttat
    17161 aaaatgttta taaacccttg ataaaatatt ataagcttat aatgcttaat aataaagtga
    17221 ttaataaata aaaataaaca tccatcaacc tttttatcaa gggtttatga aaggtttatg
    17281 atatttatca agggtttata aacccttgat aaagctatat tttccctttt ataagtttat
    17341 ttaaagtgct ataataaact taatataaca aaaaccccaa ctactggtaa tagtcggggt
    17401 ttggtaataa aacgtttaga aactgtttat ttatataatt ttcgatactt gtattatata
    17461 atgaataata tcttagtgca agcacctaaa tcattaaata aatgtaaagc taaataaaaa
    17521 cgttttatta cctcttacca aactaaaata tggaaagagg ttttttgtca tgcaaaatca
    17581 atattttaca gtgcaagaaa attacaaaga aagattttat caaatcccta aagtattctt
    17641 taccagtgaa aattataaaa atctaactaa tgatatgaaa atagcctatg ctatcttacg
    17701 tgatcgctta aatttatcta ttaaaaatag ctgggttgat gaagatggta acatttactt
    17761 tgtttattca aatgaaaagc taatggaaat cttaaattgt aaaaaagaaa agttaacaaa
    17821 aataaaaaaa gggttagaaa acgatggtct actcattcaa aaacgacgtg gtttaaataa
    17881 accaaatatt ctatatttaa tgaaacctat tgtcacagaa cgtgatattt acaaaataga
    17941 aaaagaagaa aacgatgttg aaccttacgg cgagaaggaa gttcgaaaat cgaacgtcca
    18001 gaagttcgaa aatcgaacgt ccagaagttc gaaaatcgaa cgtccagaag ttcgaaaatc
    18061 gaacactaat gatactgact ttaatgacat tgactttaat gatactgaga ataatgatat
    18121 gaatgacttg aatgatataa agtacaaaaa tgaaattagt aatcattcaa atcattcaaa
    18181 tcaatttaca cataattttg atgataaaga aatgctattg caagaattcc cagaacaact
    18241 aactaattat ttattaaaat atgattatag agatttagaa atcataaagg ctgttattct
    18301 taaagcaaaa aaatcattta attcaaggca tgaagatatg cattacatgt tagaggacat
    18361 tgaggatgaa atattaactt ctttaaaaag acttaaaaaa gctatacatg ataggggagt
    18421 taaaggccaa aaggaaacaa tcaagtcaat gcaagcttat ttaatgcaaa caattctaac
    18481 tgaacttgaa gaaacacatg ccctttatat gcgccgtaaa aacatgaaac aatataatat
    18541 ctttaatcaa taattcaaat gattttataa cactcgaaga gacatcaaaa tattccgtta
    18601 aatcatctga ctttttaact gatgacgacg aaaaaaatca agaaattgta agtgatttag
    18661 aaaaaggttt gtatcgaaaa cgtatgttaa gttatggtgg attgcttaaa caaaagcata
    18721 aaattttaaa cttagacgat gccgaagatg gtaatttgat taatacaagt gatgaagata
    18781 aaacgacaga cgaagaaaaa aagcacattc aattaccgca atttggaatt tcgaaaagca
    18841 aaattattat ttaagacatt agtgataact gatgtctttt tttattgttt ttctgtaaaa
    18901 aagtgctgtc ttatttttgt gacaaatgct gtatgtagtg tcacaaaagt gtgacactac
    18961 agctttgtat gatatcactt taaaataact taaaaccctt ggaatgtctg gccttgccag
    19021 atctatcatt tttgaatgat agcaaatttc ccttatgctc ttacggagat tttagagtta
    19081 aattaaaatt tctaagtttt tgataagaaa agccctgcag gaatttagaa aaacatgggg
    19141 aagttttaaa gtattttatg ctaattttta aatttgcatg taaatgggca gtatctaaaa
    19201 aattagtcac tgattttgct gaaatttttg tttgtgaaat tagcatatat ttatttggct
    19261 catatttgcg ttttaagaga ctgtatagat ttttaagtac aaaacctata tgatttgcct
    19321 ctaagtcttc aaaatgcctc ttaaaatcca aaataaaagt gtttaatatt gtaataagga
    19381 ttgctatttt tataaaagga gagatatca
//
