LOCUS       CP030584               30886 bp    DNA     circular BCT 10-OCT-2019
DEFINITION  Staphylococcus aureus strain ER02262.3 plasmid unnamed1, complete
            sequence.
ACCESSION   CP030584
VERSION     CP030584.1
DBLINK      BioProject: PRJNA470993
            BioSample: SAMN09483975
KEYWORDS    .
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 30886)
  AUTHORS   Sullivan,M.J., Altman,D.R., Chacko,K., Cliferri,B., Webster,E.,
            Deikus,G., Lewis,M., Khan,Z., Beckford,C., Rendo,A., Samaroo,F.,
            Sebra,R., Karam-Howlin,R., Southwick,K., Adams,E., Ying,L.,
            Kornblum,J., Factor,S., Danesh Yazdi,M., Dingle,T., Hamula,C.,
            Bashir,A., Schadt,E., Kasarskis,A., Patel,G., Wallach,F., Gibbs,K.
            and van Bakel,H.
  TITLE     Whole genome sequencing to identify and define MRSA outbreaks
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 30886)
  AUTHORS   Sullivan,M.J., Altman,D.R., Chacko,K., Cliferri,B., Webster,E.,
            Deikus,G., Lewis,M., Khan,Z., Beckford,C., Rendo,A., Samaroo,F.,
            Sebra,R., Karam-Howlin,R., Southwick,K., Adams,E., Ying,L.,
            Kornblum,J., Factor,S., Danesh Yazdi,M., Dingle,T., Hamula,C.,
            Bashir,A., Schadt,E., Kasarskis,A., Patel,G., Wallach,F., Gibbs,K.
            and van Bakel,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUN-2018) Genetics and Genomic Sciences, Icahn School
            of Medicine, One Gustave L. Levy Place Box 1498, New York, NY 10029,
            USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.2.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 202.76288297x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 06/29/2018 17:28:36
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            Annotation Method :: Best-placed reference protein set; GeneMarkS+
            Annotation Software revision      :: 4.5
            Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region
            Genes (total)                     :: 3,111
            CDS (total)                       :: 3,029
            Genes (coding)                    :: 2,926
            CDS (coding)                      :: 2,926
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 103
            Pseudo Genes (ambiguous residues) :: 0 of 103
            Pseudo Genes (frameshifted)       :: 61 of 103
            Pseudo Genes (incomplete)         :: 38 of 103
            Pseudo Genes (internal stop)      :: 28 of 103
            Pseudo Genes (multiple problems)  :: 23 of 103
            ##Genome-Annotation-Data-END##
            Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..30886
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="ER02262.3"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="unnamed1"
                     /geo_loc_name="USA:New York City"
                     /lat_lon="40.7903114 N 73.9528738 W"
                     /collection_date="2015"
                     /collected_by="Mount Sinai Hospital"
     gene            join(30886,1..1756)
                     /locus_tag="DQU94_15355"
                     /pseudo=""
     CDS             join(30886,1..1756)
                     /locus_tag="DQU94_15355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096376.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactam sensor/signal transducer BlaR1"
                     /name="beta-lactam sensor/signal transducer BlaR1"
     gene            1746..2126
                     /gene="blaI"
                     /locus_tag="DQU94_15360"
     ARG             1747..2123
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="97.62"
                     /coverage="100.0"
     gene            2390..2968
                     /locus_tag="DQU94_15365"
     CDS             2390..2968
                     /locus_tag="DQU94_15365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="QFL65031.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEAKENKNK"
                     /name="HTH domain-containing protein"
     gene            complement(3191..3376)
                     /locus_tag="DQU94_15370"
     CDS             complement(3191..3376)
                     /locus_tag="DQU94_15370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QFL65032.1"
                     /translation="MNKLEKWSLVFIIFTFLSSLALLYFKYNFSSVMPVLSLSILTILI
                     LLTSIITVVSVNDEDT"
                     /name="hypothetical protein"
     gene            3638..4312
                     /locus_tag="DQU94_15375"
     CDS             3638..4312
                     /locus_tag="DQU94_15375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="QFL65033.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(4372..4918)
                     /locus_tag="DQU94_15380"
                     /pseudo=""
     CDS             complement(4372..4918)
                     /locus_tag="DQU94_15380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199895.1"
                     /note="frameshifted; incomplete; partial on complete
                     genome; missing stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /name="replication protein"
     gene            5370..5951
                     /locus_tag="DQU94_15385"
     CDS             5370..5951
                     /locus_tag="DQU94_15385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QFL65034.1"
                     /translation="MNAIQNSISLRKILVVSLSILTILSMVLDFNFKEAQAQNKNNIAD
                     KNVETLNEKEIEKELKYIYGKIIILDKDGTAKDVNLENAKSRYGYVPEGFQKLKNDIEN
                     KKKTSSISPRAVGGNYKNSGDCFYSEVLNSYGELLTGNIITAVFEDVKAKNLKGVAKKL
                     AKIGIKGNLAGIAATMVSKDVQCNLKYGLL"
                     /name="hypothetical protein"
     gene            complement(6277..6465)
                     /locus_tag="DQU94_15390"
     CDS             complement(6277..6465)
                     /locus_tag="DQU94_15390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QFL65035.1"
                     /translation="MNKNTVLDEGYVIATILNVFFLLGLIFISHLENLYILIPYVILMG
                     INAIYLVVKVMNFKKNN"
                     /name="hypothetical protein"
     gene            6850..7041
                     /locus_tag="DQU94_15395"
     CDS             6850..7041
                     /locus_tag="DQU94_15395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001791934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QFL65036.1"
                     /translation="MIGLAKPEIPGVLRYFKVISYKAVLSYFCDTIYCVCLIFVTLHTA
                     FVTKIRQYFFIKNQQKRH"
                     /name="hypothetical protein"
     gene            complement(7048..7503)
                     /locus_tag="DQU94_15400"
     CDS             complement(7048..7503)
                     /locus_tag="DQU94_15400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="QFL65037.1"
                     /translation="MLCVENAYFRKKENYITQEEWVNLWQRALQVDYRPVANVKAIKPN
                     RKGDKDIESAIKETSKYSVKSSDFLTDDDEKNQEIVSDLEKGLYRKRMLSYGGLLKQKH
                     KILNLDDVEDGNLINASDEDKTTDEEEKAHSITAIWNFEKQNYYLRH"
                     /name="replication protein"
     gene            7562..8236
                     /locus_tag="DQU94_15405"
     CDS             7562..8236
                     /locus_tag="DQU94_15405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="QFL65038.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(8405..8620)
                     /locus_tag="DQU94_15410"
     CDS             complement(8405..8620)
                     /locus_tag="DQU94_15410"
                     /inference="COORDINATES: protein motif:HMM:PF13280.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="QFL65039.1"
                     /translation="MENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPASGGQ
                     EPESRMIEPISLGFYEQNWYLIGFAG"
                     /name="WYL domain-containing protein"
     gene            complement(8518..8976)
                     /locus_tag="DQU94_15415"
                     /pseudo=""
     CDS             complement(8518..8976)
                     /locus_tag="DQU94_15415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_003446809.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /name="transcriptional regulator"
     gene            8956..9144
                     /locus_tag="DQU94_15420"
                     /pseudo=""
     CDS             8956..9144
                     /locus_tag="DQU94_15420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913594.1"
                     /note="incomplete; partial on complete genome; missing
                     start; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            complement(9252..10046)
                     /gene="aph(3')-IIIa"
                     /locus_tag="DQU94_15425"
     ARG             complement(9256..10046)
                     /name="aph(3')-IIIa"
                     /gene="aph(3')-IIIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(10139..10585)
                     /locus_tag="DQU94_15430"
     CDS             complement(10139..10585)
                     /locus_tag="DQU94_15430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="QFL65041.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEAP
                     YLKSYQDDKCVGKVKLRKNWNRYAYIEDIAVCKDFRGQGIGSALINISIEWAKHKNLHG
                     LMLETQDNNLIACKFYHNCGFKIGSVDTMLYANFEKAVFWYLRF"
                     /name="GNAT family N-acetyltransferase"
     gene            complement(10582..11217)
                     /locus_tag="DQU94_15435"
                     /pseudo=""
     CDS             complement(10582..11217)
                     /locus_tag="DQU94_15435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="internal stop; incomplete; partial on complete
                     genome; missing start; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside adenylyltransferase"
                     /name="aminoglycoside adenylyltransferase"
     gene            complement(11358..12032)
                     /locus_tag="DQU94_15440"
     CDS             complement(11358..12032)
                     /locus_tag="DQU94_15440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="QFL65042.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            complement(12062..12265)
                     /locus_tag="DQU94_15445"
     CDS             complement(12062..12265)
                     /locus_tag="DQU94_15445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001627151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP kinase"
                     /protein_id="QFL65043.1"
                     /translation="MGFIEQIKAFILGVVEGLTEFAPVSSTGHMIIVDDMWLNTADDLG
                     SASATTFKVVIQLGGSVAKLNL"
                     /name="UDP kinase"
     gene            complement(12279..13016)
                     /locus_tag="DQU94_15450"
     CDS             complement(12279..13016)
                     /locus_tag="DQU94_15450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000369394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="QFL65044.1"
                     /translation="MDNLLRTEFIKLKRSYMFLISILGTCVAPFMVVVASFISMRTKVP
                     TPNIVFKQLFEEVSLYHMLIIGPPLYGVIIAYLFGREYIEDTLKNLLIIPISRESFLVS
                     KIILLFLWIQTLSVIAWLLTLMLGMLLHFQGLSQSLIIDSFFTFVIGGVLLWILSPPII
                     ILSIYFKNYVPTIVLTIIITLINLMTANSEHRGLFPWAAVGDISRGTLPNTYPFLLSLI
                     IIIVTSIFSVIILFSYFKKTDIS"
                     /name="ABC transporter permease"
     gene            complement(13009..13929)
                     /locus_tag="DQU94_15455"
     CDS             complement(13009..13929)
                     /locus_tag="DQU94_15455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="QFL65060.1"
                     /translation="MNNIIEINNLTKQYGSQIAVNNLSITVESGQIYGFLGRNGAGKTT
                     TIRMLLGLIKPTKGNIKIFEKEFESNKTEILKNIGAMVETPGFYSNLTAKENLTINAKI
                     LGIQKENAIEEVLEIVGLASEKVKLFKNYSLGMKQRLGIARALLHNPELLILDEPTNGL
                     DPIGIKEIRKLIKDLAQSRNITILISSHILSEIEQLVDKVGIIHNGVLLEEIMYEDLKK
                     KNRQFISISVSDEEKVACLLETNFGIYDYKIKENGEFKIYSHIDRQQEINRLLVLNNID
                     VFQMRVIEDNLETYFEDLVGGGTIG"
                     /name="ABC transporter ATP-binding protein"
     gene            complement(14054..14935)
                     /gene="nsaS"
                     /locus_tag="DQU94_15460"
                     /pseudo=""
     CDS             complement(14054..14935)
                     /gene="nsaS"
                     /locus_tag="DQU94_15460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012656189.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /name="nsaS"
     gene            complement(14932..15309)
                     /locus_tag="DQU94_15465"
                     /pseudo=""
     CDS             complement(14932..15309)
                     /locus_tag="DQU94_15465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866106.1"
                     /note="incomplete; partial on complete genome; missing
                     start; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding response regulator"
                     /name="DNA-binding response regulator"
     gene            complement(15367..16020)
                     /locus_tag="DQU94_15470"
                     /pseudo=""
     CDS             complement(15367..16020)
                     /locus_tag="DQU94_15470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001106057.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /name="IS6 family transposase"
     gene            16494..17960
                     /locus_tag="DQU94_15475"
     CDS             16494..17960
                     /locus_tag="DQU94_15475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002447408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(A)"
                     /protein_id="QFL65045.1"
                     /translation="MEQYTIKFNQINHKLTDLRSLNIGHLYAYQFEKIALIGGNGTGKT
                     TLLNMIAQKTKPESGTVETVGEIQYFEQLNMDVENDFNTLDGSLMSELHIPMHTTDSMS
                     GGEKAKYKLANVISNYSPILLLDEPTNHLDKIGKDYLKNILKYYYGTLIIVSHDRALID
                     QIADTIWDIQEDGTIRVFKGNYTQYQNQYEQEQLEQQRQYEQYISEKQRLSQASKAKRN
                     QAQQMAQASSKQKNKSIAPDRLSASKQKGTVEKAAQKQAKHIEKRMEHLEEVEKPQSYH
                     EFNFPQNKIYDIHNNYPIIAQNLTLVKGSQKLLTQVRFQIPYGKNIALVGANGVGKTTL
                     LEAIYHQIEGIDCSPKVQMAYYRQLAYEDMRDVSLLQYLMDETDSSESFSRAILNNLGL
                     NEALDRSCNVLSGGERTKLSLAVLFSTKANMLILDEPTNFLDIKTLEALEMFMNKYPGI
                     ILFTSHDTRFVKHVSDKKWELTGQSLHDIT"
                     /name="ABC-F type ribosomal protection protein Msr(A)"
     gene            18059..18958
                     /gene="mph(C)"
                     /locus_tag="DQU94_15480"
     ARG             18060..18955
                     /name="mph(C)"
                     /gene="mph(C)"
                     /gene_name="Mph(C) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            19444..20052
                     /locus_tag="DQU94_15485"
     CDS             19444..20052
                     /locus_tag="DQU94_15485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="QFL65047.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEIIETVNYLKEKDVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRV
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDKGLS"
                     /name="recombinase family protein"
     gene            20298..20636
                     /locus_tag="DQU94_15490"
     CDS             20298..20636
                     /locus_tag="DQU94_15490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QFL65048.1"
                     /translation="MNLIPFIIILIFSCLWTAITNKYLPSETLDKKGQQDRYDERQRKM
                     FIEILAKSFIWIVYCMLFTLVLKFTGLSPSIEGSWFSQYPEIFFIIVALFLMLFNYYTT
                     NKKYTSKG"
                     /name="hypothetical protein"
     gene            20641..20826
                     /locus_tag="DQU94_15495"
     CDS             20641..20826
                     /locus_tag="DQU94_15495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011276570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="QFL65049.1"
                     /translation="MKNRIREYRKQKGISQETLSKELKVSRQTINAIENNKYDPTLTLA
                     FKLARLFDTTVDELFS"
                     /name="transcriptional regulator"
     gene            complement(21053..21796)
                     /locus_tag="DQU94_15500"
     CDS             complement(21053..21796)
                     /locus_tag="DQU94_15500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002508633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="QFL65050.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     gene            22222..23205
                     /locus_tag="DQU94_15505"
     CDS             22222..23205
                     /locus_tag="DQU94_15505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="QFL65051.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNK
                     PNILYLMKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSKIERPEVRK
                     SNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNQFTHNFDDKEMLLQEFPE
                     QLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHD
                     RGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication protein"
     gene            23198..23514
                     /locus_tag="DQU94_15510"
                     /pseudo=""
     CDS             23198..23514
                     /locus_tag="DQU94_15510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002483623.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /name="replication protein"
     gene            complement(24378..25070)
                     /locus_tag="DQU94_15515"
     CDS             complement(24378..25070)
                     /locus_tag="DQU94_15515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QFL65052.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVE
                     YKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTA
                     FAAGCSVG"
                     /name="hypothetical protein"
     gene            25180..25374
                     /locus_tag="DQU94_15520"
     CDS             25180..25374
                     /locus_tag="DQU94_15520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QFL65053.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     gene            26490..27107
                     /locus_tag="DQU94_15525"
     CDS             26490..27107
                     /locus_tag="DQU94_15525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017465246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium transporter"
                     /protein_id="QFL65054.1"
                     /translation="MIQTVVAAAVLYIATAVDLLVILLIFFARAKTRKEYRDIYVGQYL
                     GSIILILVSLFLAFVLNYVPEKWILGLLGLIPIYLGIKVAIYDDCEGEKRAKKELNEKG
                     LSKLVGTVAIVTIASCGADNIGLFVPYFVTLSVTNLLLTLFVFLILIFFLVFTAQKLAN
                     IPGIGEIVEKFSRWIMAIIYIALGLFIIIENDTIQTILGFIF"
                     /name="cadmium transporter"
     gene            27126..27473
                     /locus_tag="DQU94_15530"
     CDS             27126..27473
                     /locus_tag="DQU94_15530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="QFL65055.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="transcriptional regulator"
     gene            27630..27722
                     /locus_tag="DQU94_15535"
     CDS             27630..27722
                     /locus_tag="DQU94_15535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="QFL65056.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(27894..28865)
                     /locus_tag="DQU94_15540"
     CDS             complement(27894..28865)
                     /locus_tag="DQU94_15540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH:quinone reductase"
                     /protein_id="QFL65057.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFEEFYKTIDQLLKGQHLGRTILKV"
                     /name="NADPH:quinone reductase"
     gene            28989..29408
                     /locus_tag="DQU94_15545"
     CDS             28989..29408
                     /locus_tag="DQU94_15545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="QFL65058.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            complement(29630..29725)
                     /locus_tag="DQU94_15550"
                     /pseudo=""
     CDS             complement(29630..29725)
                     /locus_tag="DQU94_15550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001560862.1"
                     /note="incomplete; partial on complete genome; missing
                     stop; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase domain-containing protein"
                     /name="O-antigen ligase domain-containing protein"
     gene            complement(29934..30779)
                     /locus_tag="DQU94_15555"
     CDS             complement(29934..30779)
                     /locus_tag="DQU94_15555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /protein_id="QFL65059.1"
                     /translation="MKKLIFLIVIALVLSACNSNSSHAKELNDLEKKYNAHIGVYALNT
                     KSGKEVKFNSDKRFAYASTSKAINSAILLEQVPYNKLNKKVHINKDDIVAYSPILEKYV
                     GKDITLKELIEASMTYSDNTANNKIIKEIGGIKKVKQRLKELGDKVTNPVRYEIELNYY
                     SPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKNFLLDLMFNNKNGDTLIKDGVPKDYKV
                     ADKSGQAITYASRNDVAFVYPKGQSEPIVLVIFTNKDNKSDKPNDKLISETAKSVMKEF
                     "
                     /name="penicillin-hydrolyzing class A beta-lactamase BlaZ"
     ARG             16495..17957
                     /name="msr(A)"
                     /gene="msr(A)"
                     /gene_name="ABC-F type ribosomal protection protein Msr(A)"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(29938..30779)
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             26491..27104
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             16495..17960
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="98.36"
                     /coverage="100.0"
     ARG             18060..18958
                     /name="mphC"
                     /gene="mphC"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="98.66"
                     /coverage="100.0"
     ARG             complement(10880..11181)
                     /name="aad(6)"
                     /gene="aad(6)"
                     /gene_name="ANT(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="99.0"
                     /coverage="36.23"
     ARG             complement(29935..30779)
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     Typing          complement(6814..6978)
                     /name="MOB_unknown"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="2.42e-81"
     Typing          23571..23718
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          complement(4370..4918)
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.455"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(7049..7505)
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          complement(21054..21796)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          22223..23205
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.593"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          23337..23506
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.605"
                     /coverage="94.0"
                     /evalue="1.04e-65"
ORIGIN
        1 tggctaaatt actaataatg agcgtagtaa gcttttgttt tatatttcta ttgttagtat
       61 tttttaggta catattaaaa cgctatttta attatagttt aaattataaa gtttggtatc
      121 taactatgct tgctggatta attcctttta tcccaattaa attctctttt ataaaattta
      181 ataatgtgaa taatcaagcg cccacagttg aaagtaagtc acacgatttg aaccataaca
      241 taaataccac caaacctatt caagagttca caacagatat ccataagttt aattgggatt
      301 caattgataa tatctgcaca gttatttgga tagttttagt tattatttta agttttaaat
      361 ttttgaaagc cttattatat cttaaatatt taaagaaaca gtcactttat ctaaacgaaa
      421 atgaaaaaaa taaaatagat acgatacttt tcaaccatca atataaaaaa atattgtgat
      481 tcgaaaagca gaggctattc aatctccaat aactttttgg tatgggaaat atattatttt
      541 gattcctagt tcatatttta aaagtgtaat tgataaaaga ctaaaatata taatactgca
      601 tgaatatgct catgctaaaa atagagatac tttacattta attatcttta atatcttctc
      661 tattattatg agttacaatc cattagtaca tattgtaaaa agaaagataa ttcatgacaa
      721 tgaagtagaa gccgatagat ttgtccttaa taatattaac aaaaatgaat ttaaaactta
      781 tgcggaatct attatggact ccgtattaaa aaccccattt tccaacaaaa atatattaag
      841 ccattcattt aatggtaaaa aatcattact caaaagtaga ttaattaata taaaagaagc
      901 cgatctgaaa aagcagtcaa aattaattct aatttttatt tgtattttta ctttttttat
      961 catgataatt caaagccagt ttttaatggg gcaatcctta actgattata attataaaaa
     1021 gcccttacaa agcgattacc aaattttaga tgaaagtaaa aattttggtt caaatagtgg
     1081 atctttcgtt atgtacagca tgaagaaaga caaatactat atttataatg aaaaagaaag
     1141 tagaaaaaga tattctcctg attcaactta caaaatttat ttagcactgt ttggacttga
     1201 ccgtcatatt ataagtgata aaaattcacg tatgtcatgg aatcataaac attatctttt
     1261 cgagtcttgg aataaggaac aagatttaaa tacagcaatg caaaattcag ttaattggta
     1321 cttcgaacgt attagtaatc aaataccaaa gaactatact gcggctcaac tcaagcaatt
     1381 aaattatggt aatgaaaatt tgggaagtta taaaagctat tggatggaag atagtttgaa
     1441 aatatctaat cttgaacaag taatagtttt taaaaatatg atggaacaaa ataaccattt
     1501 tagtaaaaaa gcaaagaatc aattatcttc ttcattattg attaagaaaa atgaaaagta
     1561 tgaactgtat gggaaaacag gtacaggtat agtaaacggg aagtataata atgggtggtt
     1621 tgtaggttac gtaattacaa atcatgataa gtattatttt gctacacatt tatcagatgg
     1681 aaacccgtct gggaaaaatg ctgaattaat aagtgaaaaa atattaaaag gaatgggtgt
     1741 tttaaatgac caataagcaa gttgaaatat ctatggctga atgggatgtt atgaatataa
     1801 tatgggataa aaaatcagta tcagctaatg aaattgtagt tgaaattcaa aaatataaag
     1861 aagttagtga taaaacgatt agaacattaa tcacaagact atataaaaaa gagattataa
     1921 aacgatacaa atcagaaaat atttattttt actcatcaaa tattaaagaa gacgatatta
     1981 aaatgaaaac tgctaaaacc ttttttaata aactgtatgg aggggatatg aaaagtttag
     2041 tgctgaattt tgcgaaaaat gaagaattaa ataacaaaga aattgaagaa ttgcgagaca
     2101 ttttaaatga tattagtaaa aagtaattag aggtatgttt caaacataat acatatgtaa
     2161 accatacttg actcttatta aattagtttt gttaatgaca tttaaaatat attattaaag
     2221 atgagagtgt ccagaaaata accattttct gtacactctt gttttttgtc taaataagta
     2281 agtattacat agaattatgt gttcaaaaac ccaacaaaaa atctatgttc acaaaagacc
     2341 tcgtaatcaa gttatggtac actaaaggtg tatataggag gtctgtattt tgaaaatagg
     2401 ttatgcaaga gtttcaactg gattacaaaa tttgaattta caggaggatc gattaaatac
     2461 atatggttgt gaaaagatat ttaatgacca tatgagtggt tcaaaaagta agcgacctgg
     2521 tttagataaa gcaattgaat ttgcgaggtc aggagatacg attgttgttt ggagattaga
     2581 tagactagga cggaacatgg aggatttaat cacgttagtt aatgaactta acgaacgagg
     2641 tgtgagtttt catagtttag aagaaaatat aacgatggat aaatcaagtt ctacaggaca
     2701 attattattt catttattcg cagcatttgc agagtttgaa cgtaatttaa ttttagagcg
     2761 atcatcagcc ggtcgaattg cagcacgtgc tagaggccga tatggaggta gacctgaaaa
     2821 attaaataaa caagatttaa acttacttaa gacactttat gataatggta cgccaattaa
     2881 aacaattgca gagcagtggc aagtttcacg tacaactatt tatcgttatc tcaataaatt
     2941 agaggcaaaa gagaataaaa acaagtagag caactaatct agcttactat aatgaatcta
     3001 ctaaataatt ttatatatca ttaacataca aagactttga ttcaatgtca ctcgatgtaa
     3061 aagagacgtt ctgacagcgt ctaaaatctc ataatatttt cctgttatga gattttaata
     3121 ataacacaag aaaaaagcgt acaaattcgt acgctttttt aatataatac ctgtttcact
     3181 aatgaacgtt ttaagtatct tcatcattaa ctgaaactac agtaataata ctcgtcaaca
     3241 atattagtat agttaaaata gaaagactta ggactggcat aaccgaacta aaattatatt
     3301 tgaaatataa aagtgctaat gaagagagaa atgtaaaaat aataaatacc aaagaccatt
     3361 tttctaattt attcattggc ttcacctctt tgaactttta tataatcata ggagatattt
     3421 ttactacgat ttataaaaaa taagaagata atcattatta aagaaacgat taatataatg
     3481 ttgaatccta tagtatcacc taattcgttt acacctttgc ctaatatcgg agatacaaag
     3541 ctttgtatta ataatgaaag agatgcccat atagtaaatg aggttctgtt gcaaagttga
     3601 atttatagta taattttaac aaaaaggagt cttctgtatg aactatttca gatataaaca
     3661 atttaacaag gatgttatca ctgtagctgt tggctactat ctaagatatg cattgagtta
     3721 tcgtgatata tctgaaatat taagggaacg tggtgtaaac gttcatcatt caacggtcta
     3781 ccgttgggtt caagaatatg ccccaatttt atatcaaatt tggaagaaaa agcataaaaa
     3841 agcttattac aaatggcgta ttgatgagac gtacatcaaa ataaaaggaa aatggagcta
     3901 tttatatcgt gccattgatg cagagggaca tacattagat atttggttgc gtaagcaacg
     3961 agataatcat tcagcatatg cgtttatcaa acgtctcatt aaacaatttg gtaaacctca
     4021 aaaggtaatt acagatcagg caccttcaac gaaggtagca atggttaaag taattaaagc
     4081 ttttaaactt aaacctgact gccattgtac atcgaaatat ctgaataacc tcattgagca
     4141 agatcaccgt catattaaag taagaaagac aaggtatcaa agtatcaata cagcaaagaa
     4201 tactttaaaa ggtattgagt gtatttacgc tctatataaa aagaaccgca ggtctcttca
     4261 gatctacgga ttttcgccat gccacgaaat tagcatcatg ctagcaagtt aagcgaacac
     4321 tgacatgata aattagtggt tagctatatt tttttacttt gcaacagaac ctaacaaaac
     4381 atgcatgtgc tgattataac taccgtcatt tttattaacg gtaacttctg ttgaacgcat
     4441 aaatccaaca agattttgtt taaccttttt atatctactc aacctatcaa atgctttagt
     4501 tagatgcttc aaactttgtt ctaaagtatc tccatctatc gcattttttt gttgaaagtg
     4561 ttaaaaacaa ccaacgtgct tttggctttt ccttaattac tttttcaatc actttttgag
     4621 cttgataact atttttcata gcacgtctcc aattacaaac cggacataat tttgatttac
     4681 aaaaccatgt cttatgtaac ttcaaatagc cttcatcagt tggcttaaat tctaaaatat
     4741 taccacattg ttttacatta aaagcctttt tgatttttaa aatttctagt atatctgcat
     4801 agcttacatt atctattttc ttttctctcc atgggcgttg tttcccactt ttcgtcatat
     4861 cttttaacgt tttattatct tgattttcgg ttatacttct agtagtatta tattgcatat
     4921 aaaaagaccc ccagtattat ttaagattcg acaccttaat aatataactg gggtttttta
     4981 ttgtcaaatt ttcctttcac gcacaaaaac acgtttaaac actgtaatat caacagttac
     5041 agctatatat ataaaatcga gttatttcta tatagtatca agacaagaag aaactcgttc
     5101 acactcgttt caaaaaacaa cctattcctt cttcttttta tgaccctcta aacctaaata
     5161 aattaatgtg aaaaccaatg aataaataaa actttctaaa aagtcaaaag gattatcaaa
     5221 taaaatcgaa ttaacaaaat taaaaattaa aaatacagat aataaaataa tcaaaaagta
     5281 aaaaaactta ttcatattaa actcctttgt ttttatatgt taatattata ttgaattcat
     5341 ttaaataaca aaacaagggg gcatttacaa tgaatgcaat tcaaaacagt atatcactaa
     5401 gaaagatttt agtagtatct ttaagtattt taaccatact ttcaatggtc ttggatttta
     5461 atttcaaaga agctcaagcc caaaacaaaa ataacattgc agataaaaac gttgaaactt
     5521 taaacgaaaa agaaattgaa aaagaactaa aatacatata tggcaaaatt attattttag
     5581 ataaagacgg aacagctaaa gatgttaatc tagaaaatgc caaatctcga tatggatatg
     5641 ttcctgaagg attccaaaaa ctaaaaaacg acatagagaa taaaaagaaa actagttcaa
     5701 tatcacctag agcagttggt gggaactaca aaaatagcgg tgactgtttc tattctgaag
     5761 ttttaaactc atatggagaa cttttaactg gaaacataat cacagcagtt tttgaagatg
     5821 ttaaagccaa aaacttaaag ggcgtagcaa aaaaattagc taaaattggg ataaaaggaa
     5881 acctagctgg aatcgcagct actatggttt cgaaggatgt acaatgtaat cttaaatacg
     5941 ggttacttta gatactattt attccaattg ctttattgac gttgagcctc ggaaccctta
     6001 acaatcccaa aacttgtcga atggtcggct taatagctca cgctatgccg acattcgtct
     6061 gcaagtttag ttaagggttc ttctcaacat caataaattt tctcggcata aatgcgtcgt
     6121 ctatttttta ttatcttcat gataatcata tttttcttcc atctcgtcaa aagcatcatc
     6181 tttatagaaa aacaaaaagt aagcaacaac accaatagga ataaaaaaac agtgtgaaaa
     6241 caagaagaaa ctcgtttcaa aatcccctca aatattctaa ttattctttt tgaaattcat
     6301 aaccttaaca accaaataaa tagcatttat tcccatcaaa ataacatacg gaattaatat
     6361 atataaattt tccaaatgag atataaaaat taatccaagt aaaaagaaaa catttaaaat
     6421 agttgctata acgtaacctt catctaacac tgtgttttta ttcaaaataa acactccttt
     6481 tttaaaaaac tttatcacaa gacttactca aattataaat acctttattt tgagttttaa
     6541 gggggtattt taaaggttta gggggtatca tataggtttt taacttaaaa atatatacaa
     6601 gctcttaaaa cgcaaatatg agccaaataa atatatggta atttcacaaa caaaaatttc
     6661 agcaaaacca gtgactaatt ttttaacact gcccatttac atgcaaatta aaaattagca
     6721 taaaatcctt taaaacttcc acatgttttt ctaaattcct gcagggcgtt ttttatcaaa
     6781 aatcgagaat ttttaatttt tctctaaaaa ctccgtaaga gcataaggag aatttgctat
     6841 cattcaaaaa tgataggtct ggcaaagcca gaaattccag gggttttaag gtattttaaa
     6901 gtgatatcat acaaagctgt actgtcttat ttttgtgaca caatatattg cgtttgtctt
     6961 atttttgtga cactacatac agcatttgtc acaaaaataa gacagtactt ttttataaaa
     7021 aatcaacaaa aaagacatta gtcaacacta atgtcttaaa taataatttt gcttttcgaa
     7081 attccaaatt gcggtaattg aatgtgcttt ttcttcttcg tctgttgttt tatcttcatc
     7141 acttgcatta atcaaattac catcttcgac atcgtctaag tttaaaattt tatgtttttg
     7201 tttaagcaat ccaccataac ttaacatacg ttttcgatac aaaccttttt ctaaatcact
     7261 tacaatttct tgattttttt catcatcatc agttaaaaaa tcagatgatt taaccgaata
     7321 ttttgaggtc tctttgattg ccgattcaat gtctttatcg ccttttctat tcggtttgat
     7381 cgctttaaca ttagcaacag gtcgatagtc aacttgtaat gctctttgcc ataaattaac
     7441 ccattcttct tgagttatat aattctcttt ttttctaaaa tatgcatttt caacacataa
     7501 caaaaggttc tgttgcaaag ttgaatttat agtataattt taacaaaaag gagtcttctg
     7561 tatgaactat ttcagatata aacaatttaa caaggatgtt atcactgtag ctgttggcta
     7621 ctatctaaga tatgcattga gttatcgtga tatatctgaa atattaaggg aacgtggtgt
     7681 aaacgttcat cattcaacgg tctaccgttg ggttcaagaa tatgccccaa ttttatatca
     7741 aatttggaag aaaaagcata aaaaagctta ttacaaatgg cgtattgatg agacgtacat
     7801 caaaataaaa ggaaaatgga gctatttata tcgtgccatt gatgcagagg gacatacatt
     7861 agatatttgg ttgcgtaagc aacgagataa tcattcagca tatgcgttta tcaaacgtct
     7921 cattaaacaa tttggtaaac ctcaaaaggt aattacagat caggcacctt caacgaaggt
     7981 agcaatggtt aaagtaatta aagcttttaa acttaaacct gactgccatt gtacatcgaa
     8041 atatctgaat aacctcattg agcaagatca ccgtcatatt aaagtaagaa agacaaggta
     8101 tcaaagtatc aatacagcaa agaatacttt aaaaggtatt gagtgtattt acgctctata
     8161 taaaaagaac cgcaggtctc ttcagatcta cggattttcg ccatgccacg aaattagcat
     8221 catgctagca agttaagcga acactgacat gataaattag tggttagcta tattttttta
     8281 ctttgcaaca gaaccagcat ttgttttaat atttgttcca aagagccatc atggctttga
     8341 cagagctctt cttctatgca aatgctttta atccgatcca cacgaaaatt cctatattca
     8401 tttcttagcc tgcaaaaccg attaagtacc agttctgttc ataaaacccc agtgatatag
     8461 gctctatcat tctgctttcc ggttcttgcc ctcctgatgc aggatattga attgatatta
     8521 cccttttatt gcagattgca gtctgaattg ctgcaataac gttatccgcc aatgtatttt
     8581 tctgtccaga tgtgctgtac acgttaatac tgttctccaa ctcctgtgca tagttttttt
     8641 caccatgctt caaaatagat ttgattttat acatagctga atcaaaatcc tttataaatg
     8701 attcatctcc atggcaattt aaaaatttcc ctgctgtaat caatgcaccc acttccgccg
     8761 ctgtaaacat taccggcaga agtaggaagc cctctacaag aaaatatcct tttccggcct
     8821 cagatccaat tggtattccg gcttcttcaa gtgtccggat atctctgtaa actgtcctta
     8881 agcttatatt aaatcgctgt gcaatttctt tggcaggaat tatttttttg attgcagctg
     8941 aataagaata gaggttactc tgttaatcct gttcaaattt tattcctcct ctgtgacttc
     9001 cataaaaagt atatcctatg cgttcttaag ctagctgctg ttagtgcttc tcattgcacc
     9061 ctggttataa aagccatact cacaaacctc ttcaccaaaa ctctttacat ctctaatata
     9121 gaactctatc tagcgaactt ttagaaaaga tataaaacat cagagtatgg acagttgcgg
     9181 atgtacttca gaaaagatta gatgtctaaa aagcttgtag ttaaagcttt ttagacatct
     9241 aaatctaggt actaaaacaa ttcatccagt aaaatataat attttatttt ctcccaatca
     9301 ggcttgatcc ccagtaagtc aaaaaatagc tcgacatact gttcttcccc gatatcctcc
     9361 ctgatcgacc ggacgcagaa ggcaatgtca taccacttgt ccgccctgcc gcttctccca
     9421 agatcaataa agccacttac tttgccatct ttcacaaaga tgttgctgtc tcccaggtcg
     9481 ccgtgggaaa agacaagttc ctcttcgggc ttttccgtct ttaaaaaatc atacagctcg
     9541 cgcggatctt taaatggagt gtcttcttcc cagttttcgc aatccacatc ggccagatcg
     9601 ttattcagta agtaatccaa ttcggctaag cggctgtcta agctattcgt atagggacaa
     9661 tccgatatgt cgatggagtg aaagagcctg atgcactccg catacagctc gataatcttt
     9721 tcagggcttt gttcatcttc atactcttcc gagcaaagga cgccatcggc ctcactcatg
     9781 agcagattgc tccagccatc atgccgttca aagtgcagga cctttggaac aggcagcttt
     9841 ccttccagcc atagcatcat gtccttttcc cgttccacat cataggtggt ccctttatac
     9901 cggctgtccg tcatttttaa atataggttt tcattttctc ccaccagctt atatacctta
     9961 gcaggagaca ttccttccgt atcttttacg cagcggtatt tttcgatcag ttttttcaat
    10021 tccggtgata ttctcatttt agccatttat tatttccttc ctcttttcta cagtatttaa
    10081 agatacccca agaagctaat tataacaaga cgaactccaa ttcactgttc cttgcattct
    10141 aaaaccttaa ataccagaaa acagcttttt caaagttggc gtataacata gtatcgacgg
    10201 agccgatttt gaaaccacaa ttatgataga atttacaagc tataaggtta ttgtcctggg
    10261 tttcaagcat tagtccatgc aagtttttat gctttgccca ttctatagat atattgataa
    10321 gcgcgctgcc tatgccttgc cccctgaaat ccttacatac ggcgatatct tctatataag
    10381 cgtaccggtt ccaatttttt cgcagtttaa cttttccgac gcatttatcg tcttggtagc
    10441 tttttaaata tggcgcttca tagagtaatt ctgtaaaggt ccaattctcg ttttcatacc
    10501 tcggtataat cttacctatc acctcaaatg gttcgctggg tttatcgata tctttcaggt
    10561 gccctgcttt catttctgta atcactgttc ccgcctctct tctatatcag cggcatatgt
    10621 gctatccagg cagccggttt taccagtgta ttttttatac atgtccctgg tatattttgt
    10681 tatattccta tcatactccg gataggcata atgaagcctt tccgccacct caccggatac
    10741 cgccctgaac aattgatggc atagaaataa tgcttcccat atgttttcat aggaatccat
    10801 ccggtaggtg gacaaaagtt tctcccacaa atcctcggat atataccttt caataaactt
    10861 atagttcttg cctacacttc atttaaagcc tgtttcgatg ccgaccttcc atgatatcat
    10921 tctcagcagc tcatggcgaa caatctgatt aaaatgatca atagcaaata aaatttcctt
    10981 acggcacaat cctttaataa cataaggtgt tacattccaa aattcattgc agcaatcatc
    11041 atactccctt gcgcttggct ttcttacatg ataatctata tcagtcggaa ctatgtccct
    11101 tttaattcta caatctttat caattagaac ctttattaat ttatcgccct ttaggtaatt
    11161 atctaactct tccaagggca ataaggtaag atcaatttta ttgtaatcat caaatagcta
    11221 taatagattt agaggtaaag aaattaaata cattgaagag cagaaagatt ttacaaaaga
    11281 gtattttaat aaaaatgatg gttctgttgc aaagtaaaaa atatagctaa tcactaatat
    11341 atcatgtcag tgttcgttta acttgctagc atgatgctaa tttcgtggca tggcgaaaat
    11401 ccgtagatct gaagagacct gcggttcttt ttatatagag cgtaaataca ctcaatacct
    11461 tttaaagtat tctttgctgt attgatactt tgataccttg tctttcttac tttaatatga
    11521 cggtgatctt gctcaatgag gttattcaga tatttcgatg tacaatggca gtcaggttta
    11581 agtttaaaag ctttaattac tttaaccatt gctaccttcg ttgaaggtgc ctgatctgta
    11641 attacctttt gaggtttacc aaattgttta atgagacgtt tgataaacgc atatgctgaa
    11701 tgattatctc gttgcttacg caaccaaata tctaatgtat gtccctctgt atcaatggca
    11761 cgatataaat agctccattt tccttttatt ttgatatacg tctcatcaat acgccatttg
    11821 taataagctt ttttatgctt tttcttccaa atttgatata aaattggggc atattcttga
    11881 acccaacggt agatcgttga atgatgaacg tttacaccac gttctcttaa tatttcagat
    11941 atatcacgat agctcaatgc atatcttaga tagtagccaa cggctacagt gataacatcc
    12001 ttgttaaatt gtttatatct gaaatagttc atacagaaga ctcctttttg ttaaaattat
    12061 attataaatt caactttgca acagaacctc ctaactgtat taccacctta aaagtagttg
    12121 cagacgcact tcctaaatcg tcagcagtgt ttaaccacat atcatcaaca ataatcatat
    12181 gacctgttga tgatactgga gcaaattctg tcaacccttc aactacacct aaaataaatg
    12241 ctttaatctg ctctataaaa cccatttttc tcctcctttt aacttatatc agttttttta
    12301 aagtatgaga ataatataat tacactgaat atagatgtaa caattatgat aattaaagat
    12361 aatagaaatg gataagtatt aggtaatgtt cctctagata tgtctccaac tgcagcccaa
    12421 ggaaataatc ctctatgttc agaattagca gtcattaaat ttatcaaagt aattattatg
    12481 gttaaaacaa ttgtgggaac ataattttta aaatatatcg acaaaataat tattggtgga
    12541 gataatatcc ataataacac tccgccaata acaaatgtaa agaatgaatc aattattaaa
    12601 ctctggctta acccttgaaa atgcaatagc atacctagca ttaaagttag caaccatgca
    12661 ataacagata gtgtttgaat ccacaagaat aataatatta ttttacttac taaaaaactt
    12721 tctctagata taggtataat taataagttt tttaaagtat cttctatata ttctcttcca
    12781 aacaaatagg ctattataac cccatataga ggaggtccaa taattagcat atgatataaa
    12841 ctgacttctt caaataactg tttaaataca atattaggag tcggtacttt cgtccgcata
    12901 ctaataaaag aagctacaac caccataaaa ggtgctacgc atgtacctaa aatacttatt
    12961 agaaacatat atgatctttt taacttaata aattctgtac ggagtagatt atccaattgt
    13021 gccacctcct actaagtctt cgaaataagt ttctagatta tcttctatca ctctcatctg
    13081 gaaaacatca atattgttta atactaataa tctattaatt tcttgttgtc tatcaatatg
    13141 tgaataaatt ttaaattcgc cattttcttt aattttatag tcataaattc cgaagttagt
    13201 ttccaacaaa catgcaactt tttcttcatc tgatactgat atacttataa attgtctgtt
    13261 cttttttttt aaatcttcat acataatttc ttctaacaaa actccgttat gaataatacc
    13321 caccttgtct actaactgct ctatttctga caatatatga cttgaaatta aaatggttat
    13381 atttctagat tgagccagat ccttaatcaa ctttctaatt tcttttatgc caataggatc
    13441 taatccattc gtcggctcat caagtatcaa taattcggga ttgtgcaata aagctctcgc
    13501 aatccctaaa cgttgcttca tacctaaaga ataattttta aacaatttta ctttttcaga
    13561 agctagtcct actatttcta acacttcttc aattgcattt tctttttgta tacctaatat
    13621 tttagcattt atagttaagt tctctttagc tgtcaaatta ctataaaaac ctggcgtttc
    13681 aaccatagca ccaatatttt ttaaaatttc agttttatta ctttcgaact ctttttcaaa
    13741 tattttaata ttacctttcg taggtttaat taagcctaaa agcattctta tagtagttgt
    13801 tttgcctgca ccatttcttc ctaaaaaacc ataaatttgt ccactttcaa cagttatact
    13861 caaattatta actgctatct gacttccata ttgctttgtt aagttattta tttcaattat
    13921 attattcaaa tttttcacct ctggcacctt tcttagtttg ttgttacctt tatcttacgc
    13981 gcgattagaa aaggctgcct ttatctattc ttacaaaaac agccgctaat cttacaaaaa
    14041 tgaaagattg gagttattta aattgaatgg tgaatattga accatcgttt aatgtagatg
    14101 tagcacttac tttatggcct aagcgctttg agattgtgct gacaatatat aaaccaatac
    14161 cgcttgattt ctcacttatt ctaccgttat agcccgagaa acctttatca aagattttcg
    14221 gtaaatcact cgcattaatg ccgataccgt tatctcggat tgataatttc tttgtatttt
    14281 cgtcaaacgt aatccacaca tctttgccac gtgcatattt taatgcattg tttaatattt
    14341 gctcaatcat aattgatgcc catttggcat ctgttaatat aaccgcttca cttttctcat
    14401 aatgcaactt tgtttgatga tgaataaact gtatcgcata acgtttaatc agtggtcgaa
    14461 ttaattcatc tacactcact tccataaaga ccatgtatgt cttttggttc atgagtttca
    14521 aatagttcag tgcaagattc gtgtaattat caatttgtaa gacttcatta cgcacgttag
    14581 aaatcacgtg ttcatcagga tcttcaagca gtaactttga tgctgtaatc ggtgtcttga
    14641 tttgatgcac ccacattaaa aaatatgact ctaactcact ttggtagtta ataaagtcat
    14701 tacgaagttt atggttttcg attcttaaat cttcgttctg ttcctgtagt gtttattctt
    14761 ttttaaagtt catgtaatgg ataccccagt aaatcattga aacaaacaat acaataccta
    14821 gaccaatcat atatgcttgc atcggcacat tatacatgaa taatataaag tagaataaag
    14881 cacaagtaag gatgacaata taaatttcac gttggattga tttcaagaaa ttcatacgtc
    14941 acctacacga tatccgacat ttttcttcgt ttcgataaaa tctgtaagtc ctagtttttg
    15001 tagctttttg cgtaaacgtg taatgttgac agcaagcgta ttgtcatcaa tgaagtgttc
    15061 tgattcccag catttttcga ttaacgcatt acgactgacg aatttgccct tgttctggaa
    15121 taagctatgc atgatttgca attcagtgtg tgtcaggtct atggtttctt cattaaattt
    15181 aagctttgct gcatcaagta gtaactcgca atcatctact gttaaattat taacttgagt
    15241 ggtgaaatca tacgtgcggc gtaatagtgc ttgaatctta gtaattgtaa cagtcatatt
    15301 aaatggctgg ttctgttgca aagtaaaaaa tatagctaat cactaatata tcatgtcagt
    15361 gttcgtttaa cttgctagca tgatgctaat ttcgtggcat ggggaaaatc cgtagatctg
    15421 aagagaccta cggttctttt tatatagagc gtaaatacat tcaatacctt ttaaagtatt
    15481 ctttgccgta ttgatacttt gatatcttgt ctttcttact ttaatatgac ggtgatcttg
    15541 ctcaatgagg ttattcagat atttcgatgt acaatgacag tcaggtttaa gtttaaaagc
    15601 tttaattatt ttagccattg ctgccttcgt tgaaggtgcc tgatctgtaa ctaccttttg
    15661 aggcttacca aattgtttaa tgagacgttt gataaacgca tatgctgaat gattatctcg
    15721 ttgcttacgc aaccaaatat ctaatgtatg tcctctgtat caatggcacg atataaatag
    15781 ctccattttc cttttatttt gatatacgtt catcaatacc atttgtataa cttttttttt
    15841 ttttttttat ttttttaata atttgatgac tttacacttc ttatatttcg atatatctag
    15901 atatgctagg tatcttgata tagcatcaac tttgttaaat tatattataa tatcaatgat
    15961 atttaatagt acaataatga taacatcctt gttaaattgt ttatatctga aatagttcat
    16021 acagaagact cctttttgtt aaaattatat tataaattca actttgcaac agaaccgtat
    16081 tttatgagta cactctaaat taaggagatg tataatcaat ctaaaattgt atttttatac
    16141 ttttgttata taatctttct acttagagat atattgtaaa aaaaccaaca aaatgttata
    16201 ttaacattac tattttatcg atgaaggagg attaaaatga cagcttctat gagactcaaa
    16261 taaacctttt tgaatacaaa actaaattaa ttcaaaaagg cttgtccgca atacacactc
    16321 ataggatgac ttatgtcatt ttttatcctt cgataggaat aataaacgct ttcaaatact
    16381 aaaacatcat aataaatttt taagtgtttg aaagtgtaat gtgaatgaga cgggagtagc
    16441 ctgtctcatt tttttgcgta cacgtccttt aaatatacaa ggagtgtata aatatggaac
    16501 aatatacaat taaatttaac caaatcaatc ataaattgac agatttacga tcacttaaca
    16561 tcggtcatct ttacgcttac caatttgaaa aaatagcact tattgggggt aatggtactg
    16621 gcaaaaccac attactaaat atgattgctc aaaaaacaaa accagaatct ggaacagttg
    16681 aaacggttgg cgaaattcaa tattttgaac agcttaacat ggatgtggaa aatgatttta
    16741 acacgttaga cggtagttta atgagtgaac tccatatacc tatgcataca accgacagta
    16801 tgagtggtgg tgaaaaagca aaatataaat tagctaatgt catatcaaat tatagtccga
    16861 tattactttt agatgaacct acaaatcact tggataaaat tggtaaagat tatctgaaaa
    16921 atattttaaa atattactat ggtactttaa ttatagtaag tcatgataga gcacttatag
    16981 accaaattgc tgacacaatt tgggatatac aagaagatgg cacaataaga gtgtttaaag
    17041 gtaattacac acagtatcaa aatcaatatg aacaagaaca gttagaacaa caacgtcaat
    17101 atgaacagta tataagtgaa aaacaaagat tgtcccaagc cagtaaagct aaacgaaatc
    17161 aagcgcaaca aatggcacaa gcatcatcaa aacaaaaaaa caaaagtata gcaccagatc
    17221 gtttaagtgc atcaaaacaa aaaggcacgg ttgagaaggc tgctcaaaaa caagctaagc
    17281 atattgaaaa aagaatggaa catttggaag aagttgaaaa accacaaagt tatcatgaat
    17341 tcaatttccc acaaaataaa atttatgata tccataataa ttatccaatc attgcacaaa
    17401 atctaacatt ggttaaagga agtcaaaaac tgctaacaca agtacgattc caaataccat
    17461 atggcaaaaa tatagcgctc gtaggtgcaa atggtgtagg taagacaact ttacttgaag
    17521 ctatttacca ccaaatagag ggaattgatt gttctcctaa agtgcaaatg gcatactatc
    17581 gtcaacttgc ttatgaagac atgcgtgacg tttcattatt gcaatattta atggatgaaa
    17641 cggattcatc agaatcattc agtagagcta ttttaaataa cttgggttta aatgaagcac
    17701 ttgatcgttc ttgtaatgtt ttgagtggtg gggaaagaac gaaattatcg ttagcagtat
    17761 tattttcaac gaaagcgaat atgttaattt tggatgaacc aactaatttt ttagatatta
    17821 aaacattaga agcattagaa atgtttatga ataaatatcc tggaatcatt ttgtttacat
    17881 cacatgatac aaggtttgtt aaacatgtat cagataaaaa atgggaatta acaggacaat
    17941 ctcttcatga tataacttaa aaactataca ctaatttata ttgaatatta ggttcattta
    18001 tatcaatata aaaaatacgt tcacaagaaa aatataatag aaataaggat ccaataaaat
    18061 gactcgacat aatgaaatta ttaaatgtgc agaaaaatat caattacaca tccaacctca
    18121 aacaatctca ttgaatgaat cgggacttga ttttcaagtt gcatttggaa aagataaaca
    18181 tggagtagaa tgggttttga gactaccaag aagacctgac gtttataaac gaacaaaacc
    18241 cgaaaaacaa acggtagact tcttacagaa gaatgtttca tttgaaatac cgaagtggaa
    18301 agtacatgca aaagacctta ttgcttaccc aaaacttaca ggtaaacccg cagccacaat
    18361 agatccagaa atacaaaatt atgtatggga aattgaacac aaaccattac cagaaaactt
    18421 tattaacaca ttagctgaaa cactcgtaga tttacacaac ataccagaag aaaacattaa
    18481 cgttcagcat ataaatatca aaaccataca agaaataaaa aatgactttc aaagaagaat
    18541 gaataaagtt aaagaaactt atggcgtatc agatgaatta tggaacagat ggaaacaatg
    18601 gttagaaaac gacgaactat ggcctcgaca tgcgaccatg atacatgggg acttacatcc
    18661 aggacatata atggtagata accaagcaaa cgtcacaggt ctcatagact ggactgaagc
    18721 aacccactcc gacccatcaa tggactttat aggacaccat cgtgtattcg acgacgaagg
    18781 attagagcaa cttataacag catacggtaa agctggaggt gaaatatggc cacgaatgaa
    18841 agagcatata atagaactca atgcagtatt cccaatgttt atcgctgagt ttgctatgga
    18901 atcaggagaa tcggcgtatg aaacgatggc attgaaagag ttaggtatga aagagtagaa
    18961 cttatattaa aagaggccca ttttaaagac gaaggcaatc ctgatgaaat tttaaaactg
    19021 cgtttaatta gtgatggtct ttggttttct ataatgtatt aaatatctgg acatggaaca
    19081 aatgcaacaa atggaaagaa tcgttttcga aatttctaac tccttaaatc aggaggataa
    19141 ataaacggtc attttcattg aaagcactta tataaatttc atcaatttta atacctaccg
    19201 taaatacatt tcataagtat taaacagatg attaaaattt ttagttaatt taaatattta
    19261 tgatagagat gaccttcaaa tgaacggttc tgttacaaag aaaaaatcta tatttatttt
    19321 tagtaagttt taattataga tatgtacact ttgagtacac cctaaccata caaaaagaat
    19381 tgttgaaatt ataacaatta aaacgtatga ttagggtgta tatttattat ggagtgaaga
    19441 tgaatgatta taggttatgc gagagtatca tcgatagatc aaaatttaga aagacaattg
    19501 gataatttaa agacgtttgg tgtggagaaa atctttacag agaaacagtc gggaaagtca
    19561 gtggaaaata gacctgtatt tcaagaagca ctcaattttg tcagaatggg agatcgattc
    19621 gttgtggaat ctattgatcg tttaggacgt aactatgatg aaattattga aactgtgaat
    19681 tatttaaaag aaaaagacgt tcagttaatg attaccagct tacctatgat gaatgaagta
    19741 attggcaatc cattactgga taagtttatg aaagatttaa tcattcaaat attagcaatg
    19801 gtttcagaac aagagagaaa tgaaagtaaa cgtcgacaag cgcaagggat tcaagttgcg
    19861 aaggaaaaag gcgtatataa agggcgccct ttactttatt caccaaatgc taaagaccca
    19921 cagaaacgtg ttatttatca tcgcgtggtg gaaatgttag aagaaggcaa agcgattagt
    19981 aagattgcga aagaagttaa tatcacaaga caaacagttt atagaattaa acatgataag
    20041 ggattatctt gataaattga ttgtcaatgc aaatgagcgt ctctcacagt gtctcaaatt
    20101 ccataacata ttattgaatt gagattttaa taattataca agaaaaaaga gtacgagttc
    20161 gcagctttct atatagtaat tgttttacta ataaggtgtt ttaaaatata ttataatgta
    20221 aaaagtattt gacatttgta tcaaaaatat ttacactcat aaatgtcaaa tactttttac
    20281 atttatgagg tgttataatg aatttaattc cttttattat tattttaatt ttttcttgtt
    20341 tatggacggc tataactaac aaatatttac cttcagaaac attagataaa aaaggacaac
    20401 aagatcgata cgatgaaaga caacgtaaaa tgtttattga aatactggct aaaagtttta
    20461 tttggattgt atattgtatg ttatttacac tagtgcttaa atttacaggt ttgtcaccaa
    20521 gtattgaagg atcttggttt tctcaatatc cagaaatttt ctttataatt gtagcactat
    20581 ttcttatgct gtttaattac tatactacaa ataaaaaata tacatctaaa ggttaaatta
    20641 atgaaaaata gaattagaga atatagaaaa caaaaaggaa tttctcaaga aactttaagt
    20701 aaagaattaa aagtgtctag gcaaactatt aatgcaatag aaaacaataa atatgatcct
    20761 acattgacat tagcatttaa gttggcaaga ttgtttgata caactgtgga tgaattattt
    20821 tcttaaccat tcatttatca caaaaagaga gtgcgaattc gcactctctt tttgtgtagt
    20881 agtactatta aattttgtct caataacgaa cgtttataac gcaatcatga tgagagtatt
    20941 aatacagtta attatttgaa atactttagt ttacataatc gatgattacc agaagttctc
    21001 actatataaa agacactaaa attttataac ttttagtgcc taatcaatta ttttagctac
    21061 caaacaaacg actccaaaac ccctttttag gttccgtttc ttcactcttt tcttctatat
    21121 cactatcatt gtcatttaga ttagctggaa cgtcttcttt ttttgcttct tcaccttgtg
    21181 tactttcgtc gctttgactt ccagatatat ccttatattg aatctctgtt tctttagttt
    21241 cttcctgatc tctgttaata tttacaggat tagtagtata tgttttttct tgtgcatcaa
    21301 cgttttgtct agtgttagta gatgtatcaa agggataatt aaggtgtttt tctttttcta
    21361 attgattttc taatttttga atctttttat tactctctaa tgccagaact tgctgatttt
    21421 caagcaattt tgatctttct tgcaactctt ttctgtaaaa ttcaattgtt gtttcatgac
    21481 gactttcttg tttttcaatt tgattattta aagtatcaat ctgattttta aggatttcta
    21541 ctatttgagc atcgcttttc gattcaaaat taatattatc cgaccctttt ttttgtttgt
    21601 cttcagtagt actttcaaaa ccatatttct ttttattttc atttactctt tgaatgattt
    21661 tttctatatc ggtatcttct ttaataaacg aagtgttttc ctgttttatt gtctctatat
    21721 tcaatcgctt aatattatta aaaatcgttt gcttactaac ccctaattct tcactcaact
    21781 ttttcacact tttcatatca tcaacccttt ataaaatgtt tataaaccct tgataaaata
    21841 ttataagctt ataatgctta ataataaagt gattaataaa taaaaataaa catccatcaa
    21901 cctttttatc aagggtttat gaaaggttta tgatatttat caagggttta taaacccttg
    21961 ataaagctat attttccctt ttataagttt atttaaagtg ctataataaa cttaatataa
    22021 caaaaacccc aactactggt aatagtcggg gtttggtaat aaaacgttta gaaactgttt
    22081 atttatataa ttttcgatac ttgtattata taatgaataa tatcttagtg caagcaccta
    22141 aatcattaaa taaatgtaaa gctaaataaa aacgttttat tacctcttac caaactaaaa
    22201 tatggaaaga ggttttttgt catgcaaaat caatatttta cagtgcaaga aaattacaaa
    22261 gaaagatttt atcaaatccc taaagtattc tttaccagtg aaaattataa aaatctaact
    22321 aatgatatga aaatagccta tgctatctta cgtgatcgct taaatttatc tattaaaaat
    22381 agctgggttg atgaagatgg taacatttac tttgtttatt caaatgaaaa gctaatggaa
    22441 atcttaaatt gtaaaaaaga aaagttaaca aaaataaaaa aagggttaga aaacgatggt
    22501 ctactcattc aaaaacgacg tggtttaaat aaaccaaata ttctatattt aatgaaacct
    22561 attgtcacag aacgtgatat ttacaaaata gaaaaagaag aaaacgatgt tgaaccttac
    22621 ggcgagaagg aagttcgaaa atcgaacgtc cagaagttcg aaaatcgaac gtccagaagt
    22681 tcgaaaatcg aacgtccaga agttcgaaaa tcgaacacta atgatactga ctttaatgac
    22741 attgacttta atgatactga gaataatgat atgaatgact tgaatgatat aaagtacaaa
    22801 aatgaaatta gtaatcattc aaatcattca aatcaattta cacataattt tgatgataaa
    22861 gaaatgctat tgcaagaatt cccagaacaa ctaactaatt atttattaaa atatgattat
    22921 agagatttag aaatcataaa ggctgttatt cttaaagcaa aaaaatcatt taattcaagg
    22981 catgaagata tgcattacat gttagaggac attgaggatg aaatattaac ttctttaaaa
    23041 agacttaaaa aagctataca tgatagggga gttaaaggcc aaaaggaaac aatcaagtca
    23101 atgcaagctt atttaatgca aacaattcta actgaacttg aagaaacaca tgccctttat
    23161 atgcgccgta aaaacatgaa acaatataat atctttaatc aataattcaa atgattttat
    23221 aacactcgaa gagacatcaa aatattccgt taaatcatct gactttttaa ctgatgacga
    23281 cgaaaaaaat caagaaattg taagtgattt agaaaaaggt ttgtatcgaa aacgtatgtt
    23341 aagttatggt ggattgctta aacaaaagca taaaatttta aacttagacg atgccgaaga
    23401 tggtaatttg attaatacaa gtgatgaaga taaaacgaca gacgaagaaa aaaagcacat
    23461 tcaattaccg caatttggaa tttcgaaaag caaaattatt atttaagaca ttagtgataa
    23521 ctgatgtctt tttttattgt ttttctgtaa aaaagtgctg tcttattttt gtgacaaatg
    23581 ctgtatgtag tgtcacaaaa gtgtgacact acagctttgt atgatatcac tttaaaataa
    23641 cttaaaaccc ttggaatgtc tggccttgcc agatctatca tttttgaatg atagcaaatt
    23701 tcccttatgc tcttacggag attttagagt taaattaaaa tttctaagtt tttgataaga
    23761 aaagccctgc aggaatttag aaaaacatgg ggaagtttta aagtatttta tgctaatttt
    23821 taaatttgca tgtaaatggg cagtatctaa aaaattagtc actgattttg ctgaaatttt
    23881 tgtttgtgaa attagcatat atttatttgg ctcatatttg cgttttaaga gactgtatag
    23941 atttttaagt acaaaaccta tatgatttgc ctctaagtct tcaaaatgcc tcttaaaatc
    24001 caaaataaaa gtgtttaata ttgtaataag gattgctatt tttataaaag gagagatatc
    24061 atgaagatta aaactttcgc tacttttact catcgtcaat tagataaaca agttaatagg
    24121 tttttaaaga atgatattca tgtattagaa attcaaacac acagtaattg gttatatatt
    24181 tcagctattg ttttttatga ggataaataa ggaacatcgt atttatgccg aaaaaattta
    24241 ttgatgttga gaagaaccct taactaaact tgcagacgaa tgtcggcata gcgtgagcta
    24301 ttaagccgac cattcgacaa gttttgggat tgttaagggt tccgaggctc aacgtcaata
    24361 aaacaattgg aataaaatca acctacagag catccagctg caaatgcagt tccgcaaact
    24421 gcttcacata caccgccggc tattggattt acgattgccc atactccaca gtagtgagca
    24481 catgcataaa gtccagccat actacaagcg aatgctttgc cgttccattt gaatcctgca
    24541 tatgttaccg gtctgttttt atcaactttt tcagccttat attcaacgta atttttgtta
    24601 ataagtattt ttccctcttt gttttcagtc atacttcttt tttcggcaat gaattttgtg
    24661 atttttttgt tgtagttatc atatattgtt tcagaaacta caatttcttt tgttttttca
    24721 tttttataag cgttattagc tatgtagcca tatgcatttt tatcatttgc ttctgtagct
    24781 agatatttta atttagaatt tttgtcttct agctttattt ttttaaatcc ttcttttttc
    24841 atttgctttt cgaatttttg catatcttca tttttatttt gcaattgttc tagaaaactt
    24901 atttctttct tggtcatttg tgatacttcg atgtttttgc ttttcaattt ttctttttga
    24961 ttttctagta aagaactttt ttgttcttca tttgcgtaag cattagaaaa attcgcgcta
    25021 aataccagta ggaacaagga aattattgaa aataatttta taattttcat ttgatacctc
    25081 caagataata agatatttta attgtataag taagcgcttt ataaaatcaa tatttatttt
    25141 aatatattta taaacatatt tttgaaagga gtctatttta tgaatgaaaa tttagaaaaa
    25201 tatataaaaa gtttgccact tttaggtttg ttaattagta ttttgttaat tgttttattc
    25261 ttttttattt tagatgttga tgaagattta ttcgtggttt ttttatactg tttattgcct
    25321 ttgatagtta atttgtctat ttatggtttt tatgtttttg ttaaaagaaa gtaagattat
    25381 gaataatttt gtttttaatt tgtatgcttt gagggggttg gaaaacggta ggtgtataga
    25441 ttagatttct tgtttttttg aaacgagtgt gaacgagttt cttcttgtct tgatttttga
    25501 taaaaacgcc ctacaggaat ttagaaaaac gtggggaagt tttaaagaat tttatgctaa
    25561 tttttaattt gcatgtaaat gggcagtgtc taaaaatagt tattgttttt gctcaaattt
    25621 ttgtttttga aaatagcata tatttatttg gctcatattt gcgttttaaa agcatatata
    25681 agttttagat ataaaactat atgaatcacc cctaaatctt taaaatgccc tcttaaaatt
    25741 caaaataagg gcataaaaaa taaaagctac cccagataaa gtgaggtagc tttttctttc
    25801 atacggtcta tttatttttc tttcgacgcc gtatcgtcga tgtaattcaa aaaagttatg
    25861 ggctataaat ctacatcact ttttcaagaa tgtagtagca atattcaacg caaattaatt
    25921 tttataactg ctcggaatat ctcaagccgt ttctttaatt ttgaaataaa aaaatcgacg
    25981 aaggtcgatt acgtttttgc acatgtcgat ttatccgacg tataagtgcg cccttacggg
    26041 atttaactag attataacga cgaattttag acctgtaaag caataacaat taggtctacc
    26101 aggtagataa agtgtacaaa gtagaaccga aaaagttatt tattttgaag atttttcgta
    26161 gatataattt gctaataaac ttcctaaaac tgaataaaga aaaatagtta aactcatgta
    26221 atcactccat aattctgaag tgtctccatg tctacgcata gacacgcatt tatgccgaaa
    26281 aaatttattg atgttgagaa gaacccttaa ctaaacttgc agacgaatgt cggcatagcg
    26341 tgagctatta agccgaccat tcgacaagtt ttgggattgt taagggttcc gaggctcaac
    26401 gtcaataaag caattggaat aaagcaccta tgattattta aaaatataag ttataataca
    26461 ttcaaaaata tttttgaatg aggtgtatta tgattcaaac ggttgttgct gctgctgttc
    26521 tttatattgc tacagcagtt gatttattag taattttatt aatatttttt gctagagcaa
    26581 agactagaaa agaatataga gatatttatg ttggtcaata tttagggtct attattttaa
    26641 tattagttag tttgttttta gcttttgtat taaattatgt tccagaaaag tggatattag
    26701 gtttattggg tttaatacca atttatcttg gaattaaagt ggctatttat gatgattgtg
    26761 aaggagaaaa gagagctaaa aaagaattga atgaaaaagg attgtctaaa ttagttggta
    26821 cggttgcaat tgttacgata gcaagttgtg gcgccgataa tattggttta tttgttccgt
    26881 attttgtgac attaagtgtt actaatttat tacttactct gtttgtcttt ttaattttaa
    26941 ttttcttctt ggtgtttact gcacaaaaat tagctaatat tccaggaatt ggagaaattg
    27001 ttgagaaatt tagtcgttgg attatggcta ttatttatat agctttaggt ttatttatta
    27061 ttattgaaaa tgacactatt caaacaattt taggatttat attttaattt agggtgtgat
    27121 tttatatgag ttatgaaaat acttgtgatg tgatctgtgt acatgaggat aaagttaaca
    27181 atgctttaag ttttttagaa gatgataaat ctaagaaatt acttaacatt ttagaaaaaa
    27241 tttgtgatga gaagaaattg aaaatcatat tatctttgat taaagaagat gagttgtgtg
    27301 tttgtgatat ttctttgata ttgaaaatga gtgttgcttc aacttcacat catttaaggc
    27361 ttttatataa aaatgaggta cttgattttt ataaagatgg aaagatggca tattatttta
    27421 ttaaagacga tgaaataaga gagtttttct ctaaaaatca tgagggtttt tgaaacgagt
    27481 ttcttcttgt cttgatacta taaaaaacaa agttatataa cataagacga cttatcggaa
    27541 gtagatatgc ttgtatattc acagatggta taataataga gtcgcctatc tctcaggcgt
    27601 caattgacga agagaggagg tgcattactt tgctaatcat tttcgttcac atcatagcac
    27661 cagtcatcag tggctgtgct gttgcgtatt atacttattg gcttagtaaa cgcaacaaat
    27721 aattaatagg cgactttata agccagcatc gaaaaaatcc ccacactact gcaatagtgt
    27781 ggggattggt gcattaattg ttaatcattt tcgttatata aattataaca ctggttagta
    27841 gagaaatgca aaatgattga attaatagta aatgtattaa tgaatactca cacttatact
    27901 tttaaaatag ttcttcctaa atgttgtcct tttaaaagct gatctatcgt tttatagaat
    27961 tcttcaaatc caatttcatt gtatagaagt gaatttccta tattccattc atttgctaac
    28021 ttactccata tatcttcacg gatattatga tcaacatata cagaatcaat gccaattaat
    28081 ttaatacctc taagaataaa cggtaatata ttagcgttaa gtgaatttcc tgctacattt
    28141 ccacatacag tagcaacacc ttgataattt agacgtttta aaccgtataa tgttacatta
    28201 ctccccactg tatctaagaa ataatcaaaa ataccttttt taagcggttt attatcatct
    28261 tcaattatta ttacttgttt tgcacctaat ttttttgcga tttctatttg cttttctttt
    28321 cttacgatag cagtgatatt ttcatatcca attttatgta aaatttgtat agcaacactg
    28381 cccacaccac ctgtagcccc agacactaaa atttcaggtt gtgatttgat attcattcca
    28441 tatttttcta gttcaaaaat tgataatgct gccgtaaaac cggctgtgcc atataccata
    28501 gactctttaa tagacatttc ttggggaata ggaacaatcc actctccagg cacttgtgca
    28561 tattctgaaa atccacctgt atgtgtcacg ccaacatcat aaccagtaac taatacatta
    28621 tcgccttctt taaacttatc attcgaactt gattcaacaa tacctgcaaa atctatacca
    28681 ggaatcatag gataatctct aattacaccg cctttatatt gtaaagctag catatcctta
    28741 taatttattg aagagtatac cacttttact aatacatcac ccttcgataa atgagattca
    28801 tcaacttttt ctactttata actaacattt gatgcacttt ttctcactac taccgcattg
    28861 aacatttatt agccttcttt cacaattgtt ttgtagaagt atgtttttgt tgcaaaacta
    28921 ttttcctaca aaacttatca tgatatgata agcgagtcaa tactaatgat ttaagagagg
    28981 ttttagttgt ggaattagat aattgtataa attatttgtt gagtacttct cagaatagag
    29041 tttttaaaca ttttaaaagt ttattaagtc cctataatat tactccagca gaatatggtg
    29101 ttttgaattg cttgattaat agtaatttga atacacctaa agcgattggt aatactttaa
    29161 atttagaacc ttcaacaata tctggaatat tagataagat gtccaaaaag gatctaataa
    29221 cacgtcaaac tgataatgaa aatagaagaa ctgtgctaat aaacagtaca aataaagcaa
    29281 aagacttatg gccaacatta gaaaagaaag cctatcaact taataatcat tacttcgcta
    29341 atttaactaa tgaagaaact gtagtgttta aaaagatatt actaaagata aataaaacta
    29401 cgttttaatt tttacgttat aaaaaagttg aagtgcgaat tataatcgag taaatataaa
    29461 tgatagctta gcttaattat atattaaagc caactatact tttattcccg aaaaacctac
    29521 tatccaaatt tctaagatac tttagcctct ataataaaca tattgtaata taatttatgt
    29581 attatttagg tttaccctaa tcgaacaata aaaaatactt gtaaaatgct attgtcactt
    29641 tgcttgatat atgagaatta tttaacctta taaatgagaa aaaagcaacg cactttaaat
    29701 aagatacgtt gctttttcga ttgatgaaca cctataatta aactattcat ctattattta
    29761 tgattttttg tatatacaat atttctagtt tgttaaagag aattaagaaa ataaatctcg
    29821 aaaataataa agggaaaatc agtttttgat atcaaaatta tacatgtcaa cgataataca
    29881 aaatataata caaactataa gatgttatca gtatttatta tgcatttaga atattaaaat
    29941 tccttcatta cactcttggc ggtttcactt atcaacttat catttggctt atcactttta
    30001 ttgtctttat tcgtaaaaat gactaaaaca ataggttcag attggccctt aggataaaca
    30061 aaagcaacat catttctaga agcatatgtt attgcttgac cacttttatc agcaacctta
    30121 tagtcttttg gaacaccatc tttaattaaa gtgtctccgt ttttattatt aaacattaaa
    30181 tcaagtaaga aatttttatt ttttttgctt aattttccat ttgcgataag tttatttaaa
    30241 gtcttgccga aagcagcagg cgttgaagta tcttttttgc tctttggtga atagtaattt
    30301 aattctatct catatctaac tggatttgtt actttatctc ctagttcttt tagacgttgt
    30361 ttaacttttt tgattccacc gatttctttt ataattttat tgtttgctgt attatcacta
    30421 tatgtcattg aagcctcaat aagttctttt aaagtgatat cttttcctac atatttttct
    30481 aaaataggag aataagcaac tatatcatct ttgttaatat gtactttttt atttaactta
    30541 ttataaggta cttgttctaa caaaatagca ctatttatcg cttttgaagt cgaagcatag
    30601 gcaaatctct tatctgaatt aaattttact tccttaccac ttttagtatt taaagcataa
    30661 acaccaatat gagcattata ttttttttct aaatcattta actctttggc atgtgaactg
    30721 tttgaattac atgcacttaa aactaaagca attacaatta aaaatattaa ctttttcaaa
    30781 ataaaccctc cgatattaca gttgtaattt ttataaatca ataatattac aattgtaata
    30841 ttgatgtcaa ttgtttatta taaatatttg aaagaaggtg tcaaaa
//
