LOCUS       CP030560               27068 bp    DNA     circular BCT 10-OCT-2019
DEFINITION  Staphylococcus aureus strain ER01457.3 plasmid unnamed2, complete
            sequence.
ACCESSION   CP030560
VERSION     CP030560.1
DBLINK      BioProject: PRJNA470993
            BioSample: SAMN09483948
KEYWORDS    .
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 27068)
  AUTHORS   Sullivan,M.J., Altman,D.R., Chacko,K., Cliferri,B., Webster,E.,
            Deikus,G., Lewis,M., Khan,Z., Beckford,C., Rendo,A., Samaroo,F.,
            Sebra,R., Karam-Howlin,R., Southwick,K., Adams,E., Ying,L.,
            Kornblum,J., Factor,S., Danesh Yazdi,M., Dingle,T., Hamula,C.,
            Bashir,A., Schadt,E., Kasarskis,A., Patel,G., Wallach,F., Gibbs,K.
            and van Bakel,H.
  TITLE     Whole genome sequencing to identify and define MRSA outbreaks
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 27068)
  AUTHORS   Sullivan,M.J., Altman,D.R., Chacko,K., Cliferri,B., Webster,E.,
            Deikus,G., Lewis,M., Khan,Z., Beckford,C., Rendo,A., Samaroo,F.,
            Sebra,R., Karam-Howlin,R., Southwick,K., Adams,E., Ying,L.,
            Kornblum,J., Factor,S., Danesh Yazdi,M., Dingle,T., Hamula,C.,
            Bashir,A., Schadt,E., Kasarskis,A., Patel,G., Wallach,F., Gibbs,K.
            and van Bakel,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUN-2018) Genetics and Genomic Sciences, Icahn School
            of Medicine, One Gustave L. Levy Place Box 1498, New York, NY 10029,
            USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.2.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 279.424642522x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 06/29/2018 17:33:35
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            Annotation Method :: Best-placed reference protein set; GeneMarkS+
            Annotation Software revision      :: 4.5
            Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region
            Genes (total)                     :: 3,094
            CDS (total)                       :: 3,015
            Genes (coding)                    :: 2,929
            CDS (coding)                      :: 2,929
            Genes (RNA)                       :: 79
            rRNAs                             :: 6, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 43 of 86
            Pseudo Genes (incomplete)         :: 38 of 86
            Pseudo Genes (internal stop)      :: 24 of 86
            Pseudo Genes (multiple problems)  :: 18 of 86
            ##Genome-Annotation-Data-END##
            Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..27068
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="ER01457.3"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="unnamed2"
                     /geo_loc_name="USA:New York City"
                     /lat_lon="40.7903114 N 73.9528738 W"
                     /collection_date="2015"
                     /collected_by="Mount Sinai Hospital"
     gene            join(26876..27068,1..2)
                     /locus_tag="DQU67_00195"
     CDS             join(26876..27068,1..2)
                     /locus_tag="DQU67_00195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QFL73866.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     gene            1118..1735
                     /locus_tag="DQU67_00200"
     CDS             1118..1735
                     /locus_tag="DQU67_00200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017465246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium transporter"
                     /protein_id="QFL73840.1"
                     /translation="MIQTVVAAAVLYIATAVDLLVILLIFFARAKTRKEYRDIYVGQYL
                     GSIILILVSLFLAFVLNYVPEKWILGLLGLIPIYLGIKVAIYDDCEGEKRAKKELNEKG
                     LSKLVGTVAIVTIASCGADNIGLFVPYFVTLSVTNLLLTLFVFLILIFFLVFTAQKLAN
                     IPGIGEIVEKFSRWIMAIIYIALGLFIIIENDTIQTILGFIF"
                     /name="cadmium transporter"
     gene            1754..2101
                     /locus_tag="DQU67_00205"
     CDS             1754..2101
                     /locus_tag="DQU67_00205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="QFL73841.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="transcriptional regulator"
     gene            2258..2350
                     /locus_tag="DQU67_00210"
     CDS             2258..2350
                     /locus_tag="DQU67_00210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="QFL73842.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(2522..3493)
                     /locus_tag="DQU67_00215"
     CDS             complement(2522..3493)
                     /locus_tag="DQU67_00215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH:quinone reductase"
                     /protein_id="QFL73843.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFEEFYKTIDQLLKGQHLGRTILKV"
                     /name="NADPH:quinone reductase"
     gene            3617..4036
                     /locus_tag="DQU67_00220"
     CDS             3617..4036
                     /locus_tag="DQU67_00220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="QFL73844.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            complement(4258..4353)
                     /locus_tag="DQU67_00225"
                     /pseudo=""
     CDS             complement(4258..4353)
                     /locus_tag="DQU67_00225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001560862.1"
                     /note="incomplete; partial on complete genome; missing
                     stop; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase domain-containing protein"
                     /name="O-antigen ligase domain-containing protein"
     gene            complement(4562..5407)
                     /locus_tag="DQU67_00230"
     CDS             complement(4562..5407)
                     /locus_tag="DQU67_00230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /protein_id="QFL73845.1"
                     /translation="MKKLIFLIVIALVLSACNSNSSHAKELNDLEKKYNAHIGVYALNT
                     KSGKEVKFNSDKRFAYASTSKAINSAILLEQVPYNKLNKKVHINKDDIVAYSPILEKYV
                     GKDITLKELIEASMTYSDNTANNKIIKEIGGIKKVKQRLKELGDKVTNPVRYEIELNYY
                     SPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKNFLLDLMFNNKNGDTLIKDGVPKDYKV
                     ADKSGQAITYASRNDVAFVYPKGQSEPIVLVIFTNKDNKSDKPNDKLISETAKSVMKEF
                     "
                     /name="penicillin-hydrolyzing class A beta-lactamase BlaZ"
     gene            5514..7271
                     /locus_tag="DQU67_00235"
     CDS             5514..7271
                     /locus_tag="DQU67_00235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactam sensor/signal transducer BlaR1"
                     /protein_id="QFL73846.1"
                     /translation="MAKLLIMSVVSFCFIFLLLVFFRYILKRYFNYSLNYKVWYLTMLA
                     GLIPFIPIKFSFIKFNNVNNQAPTVESKSHDLNHNINTTKPIQEFTTDIHKFNWDSIDN
                     ICTVIWIVLVIILSFKFLKALLYLKYLKKQSLYLNENEKNKIDTILFNHQYKKNIVIRK
                     AEAIQSPITFWYGKYIILIPSSYFKSVIDKRLKYIILHEYAHAKNRDTLHLIIFNIFSI
                     IMSYNPLVHIVKRKIIHDNEVEADRFVLNNINKNEFKTYAESIMDSVLKTPFSNKNILS
                     HSFNGKKSLLKSRLINIKEADLKKQSKLILIFICIFTFFIMIIQSQFLMGQSLTDYNYK
                     KPLQSDYQILDESKNFGSNSGSFVMYSMKKDKYYIYNEKESRKRYSPDSTYKIYLALFG
                     LDRHIISDKNSRMSWNHKHYLFESWNKEQDLNTAMQNSVNWYFERISNQIPKNYTAAQL
                     KQLNYGNENLGSYKSYWMEDSLKISNLEQVIVFKNMMEQNNHFSKKAKNQLSSSLLIKK
                     NEKYELYGKTGTGIVNGKYNNGWFVGYVITNHDKYYFATHLSDGNPSGKNAELISEKIL
                     KGMGVLNDQ"
                     /name="beta-lactam sensor/signal transducer BlaR1"
     gene            7261..7641
                     /gene="blaI"
                     /locus_tag="DQU67_00240"
     ARG             7262..7638
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="98.41"
                     /coverage="100.0"
     gene            7905..8483
                     /locus_tag="DQU67_00245"
     CDS             7905..8483
                     /locus_tag="DQU67_00245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="QFL73848.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEAKENKNK"
                     /name="HTH domain-containing protein"
     gene            complement(8706..8891)
                     /locus_tag="DQU67_00250"
     CDS             complement(8706..8891)
                     /locus_tag="DQU67_00250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QFL73849.1"
                     /translation="MNKLEKWSLVFIIFTFLSSLALLYFKYNFSSVMPVLSLSILTILI
                     LLTSIITVVSVNDEDT"
                     /name="hypothetical protein"
     gene            9153..9827
                     /locus_tag="DQU67_00255"
     CDS             9153..9827
                     /locus_tag="DQU67_00255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="QFL73850.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(9996..10211)
                     /locus_tag="DQU67_00260"
     CDS             complement(9996..10211)
                     /locus_tag="DQU67_00260"
                     /inference="COORDINATES: protein motif:HMM:PF13280.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="QFL73851.1"
                     /translation="MENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPASGGQ
                     EPESRMIEPISLGFYEQNWYLIGFAG"
                     /name="WYL domain-containing protein"
     gene            complement(10109..10567)
                     /locus_tag="DQU67_00265"
                     /pseudo=""
     CDS             complement(10109..10567)
                     /locus_tag="DQU67_00265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_003446809.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /name="transcriptional regulator"
     gene            10547..10735
                     /locus_tag="DQU67_00270"
                     /pseudo=""
     CDS             10547..10735
                     /locus_tag="DQU67_00270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913594.1"
                     /note="incomplete; partial on complete genome; missing
                     start; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /name="hypothetical protein"
     gene            complement(10843..11637)
                     /gene="aph(3')-IIIa"
                     /locus_tag="DQU67_00275"
     ARG             complement(10847..11637)
                     /name="aph(3')-IIIa"
                     /gene="aph(3')-IIIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(11730..12260)
                     /gene="sat4"
                     /locus_tag="DQU67_00280"
     ARG             complement(11734..12260)
                     /name="sat4"
                     /gene="sat4"
                     /gene_name="streptothricin N-acetyltransferase Sat4"
                     /tool="amrfinderplus"
                     /drug_class="STREPTOTHRICIN"
                     /identity="97.78"
                     /coverage="100.0"
     gene            complement(12257..12892)
                     /locus_tag="DQU67_00285"
                     /pseudo=""
     CDS             complement(12257..12892)
                     /locus_tag="DQU67_00285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="internal stop; incomplete; partial on complete
                     genome; missing start; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside adenylyltransferase"
                     /name="aminoglycoside adenylyltransferase"
     gene            complement(13033..13707)
                     /locus_tag="DQU67_00290"
     CDS             complement(13033..13707)
                     /locus_tag="DQU67_00290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="QFL73854.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            complement(13737..13940)
                     /locus_tag="DQU67_00295"
     CDS             complement(13737..13940)
                     /locus_tag="DQU67_00295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001627151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP kinase"
                     /protein_id="QFL73855.1"
                     /translation="MGFIEQIKAFILGVVEGLTEFAPVSSTGHMIIVDDMWLNTADDLG
                     SASATTFKVVIQLGGSVAKLNL"
                     /name="UDP kinase"
     gene            complement(13954..14691)
                     /locus_tag="DQU67_00300"
     CDS             complement(13954..14691)
                     /locus_tag="DQU67_00300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000369394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="QFL73856.1"
                     /translation="MDNLLRTEFIKLKRSYMFLISILGTCVAPFMVVVASFISMRTKVP
                     TPNIVFKQLFEEVSLYHMLIIGPPLYGVIIAYLFGREYIEDTLKNLLIIPISRESFLVS
                     KIILLFLWIQTLSVIAWLLTLMLGMLLHFQGLSQSLIIDSFFTFVIGGVLLWILSPPII
                     ILSIYFKNYVPTIVLTIIITLINLMTANSEHRGLFPWAAVGDISRGTLPNTYPFLLSLI
                     IIIVTSIFSVIILFSYFKKTDIS"
                     /name="ABC transporter permease"
     gene            complement(14684..15604)
                     /locus_tag="DQU67_00305"
     CDS             complement(14684..15604)
                     /locus_tag="DQU67_00305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="QFL73867.1"
                     /translation="MNNIIEINNLTKQYGSQIAVNNLSITVESGQIYGFLGRNGAGKTT
                     TIRMLLGLIKPTKGNIKIFEKEFESNKTEILKNIGAMVETPGFYSNLTAKENLTINAKI
                     LGIQKENAIEEVLEIVGLASEKVKLFKNYSLGMKQRLGIARALLHNPELLILDEPTNGL
                     DPIGIKEIRKLIKDLAQSRNITILISSHILSEIEQLVDKVGIIHNGVLLEEIMYEDLKK
                     KNRQFISISVSDEEKVACLLETNFGIYDYKIKENGEFKIYSHIDRQQEINRLLVLNNID
                     VFQMRVIEDNLETYFEDLVGGGTIG"
                     /name="ABC transporter ATP-binding protein"
     gene            complement(15729..16610)
                     /gene="nsaS"
                     /locus_tag="DQU67_00310"
                     /pseudo=""
     CDS             complement(15729..16610)
                     /gene="nsaS"
                     /locus_tag="DQU67_00310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012656189.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /name="nsaS"
     gene            complement(16607..16984)
                     /locus_tag="DQU67_00315"
                     /pseudo=""
     CDS             complement(16607..16984)
                     /locus_tag="DQU67_00315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866106.1"
                     /note="incomplete; partial on complete genome; missing
                     start; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding response regulator"
                     /name="DNA-binding response regulator"
     gene            complement(17042..17716)
                     /locus_tag="DQU67_00320"
     CDS             complement(17042..17716)
                     /locus_tag="DQU67_00320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001106057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="QFL73857.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            18190..19656
                     /locus_tag="DQU67_00325"
     CDS             18190..19656
                     /locus_tag="DQU67_00325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002447408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(A)"
                     /protein_id="QFL73858.1"
                     /translation="MEQYTIKFNQINHKLTDLRSLNIGHLYAYQFEKIALIGGNGTGKT
                     TLLNMIAQKTKPESGTVETVGEIQYFEQLNMDVENDFNTLDGSLMSELHIPMHTTDSMS
                     GGEKAKYKLANVISNYSPILLLDEPTNHLDKIGKDYLKNILKYYYGTLIIVSHDRALID
                     QIADTIWDIQEDGTIRVFKGNYTQYQNQYEQEQLEQQRQYEQYISEKQRLSQASKAKRN
                     QAQQMAQASSKQKNKSIAPDRLSASKQKGTVEKAAQKQAKHIEKRMEHLEEVEKPQSYH
                     EFNFPQNKIYDIHNNYPIIAQNLTLVKGSQKLLTQVRFQIPYGKNIALVGANGVGKTTL
                     LEAIYHQIEGIDCSPKVQMAYYRQLAYEDMRDVSLLQYLMDETDSSESFSRAILNNLGL
                     NEALDRSCNVLSGGERTKLSLAVLFSTKANMLILDEPTNFLDIKTLEALEMFMNKYPGI
                     ILFTSHDTRFVKHVSDKKWELTGQSLHDIT"
                     /name="ABC-F type ribosomal protection protein Msr(A)"
     gene            19755..20654
                     /gene="mph(C)"
                     /locus_tag="DQU67_00330"
     ARG             19756..20651
                     /name="mph(C)"
                     /gene="mph(C)"
                     /gene_name="Mph(C) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            21140..21748
                     /locus_tag="DQU67_00335"
     CDS             21140..21748
                     /locus_tag="DQU67_00335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="QFL73860.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEIIETVNYLKEKDVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRV
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDKGLS"
                     /name="recombinase family protein"
     gene            21994..22332
                     /locus_tag="DQU67_00340"
     CDS             21994..22332
                     /locus_tag="DQU67_00340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QFL73861.1"
                     /translation="MNLIPFIIILIFSCLWTAITNKYLPSETLDKKGQQDRYDERQRKM
                     FIEILAKSFIWIVYCMLFTLVLKFTGLSPSIEGSWFSQYPEIFFIIVALFLMLFNYYTT
                     NKKYTSKG"
                     /name="hypothetical protein"
     gene            22337..22522
                     /locus_tag="DQU67_00345"
     CDS             22337..22522
                     /locus_tag="DQU67_00345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011276570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="QFL73862.1"
                     /translation="MKNRIREYRKQKGISQETLSKELKVSRQTINAIENNKYDPTLTLA
                     FKLARLFDTTVDELFS"
                     /name="transcriptional regulator"
     gene            complement(22749..23492)
                     /locus_tag="DQU67_00350"
     CDS             complement(22749..23492)
                     /locus_tag="DQU67_00350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002508633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="QFL73863.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     gene            23918..24901
                     /locus_tag="DQU67_00355"
     CDS             23918..24901
                     /locus_tag="DQU67_00355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="QFL73864.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNK
                     PNILYLMKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSKIERPEVRK
                     SNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNQFTHNFDDKEMLLQEFPE
                     QLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHD
                     RGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication protein"
     gene            24894..25210
                     /locus_tag="DQU67_00360"
                     /pseudo=""
     CDS             24894..25210
                     /locus_tag="DQU67_00360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002483623.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /name="replication protein"
     gene            complement(26074..26766)
                     /locus_tag="DQU67_00365"
     CDS             complement(26074..26766)
                     /locus_tag="DQU67_00365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QFL73865.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVE
                     YKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTA
                     FAAGCSVG"
                     /name="hypothetical protein"
     ARG             18191..19653
                     /name="msr(A)"
                     /gene="msr(A)"
                     /gene_name="ABC-F type ribosomal protection protein Msr(A)"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             5515..7268
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.38"
                     /coverage="100.0"
     ARG             complement(4566..5407)
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             1119..1732
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             18191..19656
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="98.36"
                     /coverage="100.0"
     ARG             19756..20654
                     /name="mphC"
                     /gene="mphC"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="98.66"
                     /coverage="100.0"
     ARG             complement(11731..12248)
                     /name="SAT-4"
                     /gene="SAT-4"
                     /gene_name="streptothricin acetyltransferase (SAT)"
                     /tool="rgi"
                     /drug_class="nucleoside antibiotic"
                     /identity="97.16"
                     /coverage="95.56"
     ARG             complement(12555..12856)
                     /name="aad(6)"
                     /gene="aad(6)"
                     /gene_name="ANT(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="99.0"
                     /coverage="36.23"
     ARG             complement(4563..5407)
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     Typing          25267..25414
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          complement(22750..23492)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          23919..24901
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.593"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          25033..25202
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.605"
                     /coverage="91.0"
                     /evalue="1.04e-65"
ORIGIN
        1 aagattatga ataattttgt ttttaatttg tatgctttga gggggttgga aaacggtagg
       61 tgtatagatt agatttcttg tttttttgaa acgagtgtga acgagtttct tcttgtcttg
      121 atttttgata aaaacgccct acaggaattt agaaaaacgt ggggaagttt taaagaattt
      181 tatgctaatt tttaatttgc atgtaaatgg gcagtgtcta aaaatagtta ttgtttttgc
      241 tcaaattttt gtttttgaaa atagcatata tttatttggc tcatatttgc gttttaaaag
      301 catatataag ttttagatat aaaactatat gaatcacccc taaatcttta aaatgccctc
      361 ttaaaattca aaataagggc ataaaaaata aaagctaccc cagataaagt gaggtagctt
      421 tttctttcat acggtctatt tatttttctt tcgacgccgt atcgtcgatg taattcaaaa
      481 aagttatggg ctataaatct acatcacttt ttcaagaatg tagtagcaat attcaacgca
      541 aattaatttt tataactgct cggaatatct caagccgttt ctttaatttt gaaataaaaa
      601 aatcgacgaa ggtcgattac gtttttgcac atgtcgattt atccgacgta taagtgcgcc
      661 cttacgggat ttaactagat tataacgacg aattttagac ctgtaaagca ataacaatta
      721 ggtctaccag gtagataaag tgtacaaagt agaaccgaaa aagttattta ttttgaagat
      781 ttttcgtaga tataatttgc taataaactt cctaaaactg aataaagaaa aatagttaaa
      841 ctcatgtaat cactccataa ttctgaagtg tctccatgtc tacgcataga cacgcattta
      901 tgccgaaaaa atttattgat gttgagaaga acccttaact aaacttgcag acgaatgtcg
      961 gcatagcgtg agctattaag ccgaccattc gacaagtttt gggattgtta agggttccga
     1021 ggctcaacgt caataaagca attggaataa agcacctatg attatttaaa aatataagtt
     1081 ataatacatt caaaaatatt tttgaatgag gtgtattatg attcaaacgg ttgttgctgc
     1141 tgctgttctt tatattgcta cagcagttga tttattagta attttattaa tattttttgc
     1201 tagagcaaag actagaaaag aatatagaga tatttatgtt ggtcaatatt tagggtctat
     1261 tattttaata ttagttagtt tgtttttagc ttttgtatta aattatgttc cagaaaagtg
     1321 gatattaggt ttattgggtt taataccaat ttatcttgga attaaagtgg ctatttatga
     1381 tgattgtgaa ggagaaaaga gagctaaaaa agaattgaat gaaaaaggat tgtctaaatt
     1441 agttggtacg gttgcaattg ttacgatagc aagttgtggc gccgataata ttggtttatt
     1501 tgttccgtat tttgtgacat taagtgttac taatttatta cttactctgt ttgtcttttt
     1561 aattttaatt ttcttcttgg tgtttactgc acaaaaatta gctaatattc caggaattgg
     1621 agaaattgtt gagaaattta gtcgttggat tatggctatt atttatatag ctttaggttt
     1681 atttattatt attgaaaatg acactattca aacaatttta ggatttatat tttaatttag
     1741 ggtgtgattt tatatgagtt atgaaaatac ttgtgatgtg atctgtgtac atgaggataa
     1801 agttaacaat gctttaagtt ttttagaaga tgataaatct aagaaattac ttaacatttt
     1861 agaaaaaatt tgtgatgaga agaaattgaa aatcatatta tctttgatta aagaagatga
     1921 gttgtgtgtt tgtgatattt ctttgatatt gaaaatgagt gttgcttcaa cttcacatca
     1981 tttaaggctt ttatataaaa atgaggtact tgatttttat aaagatggaa agatggcata
     2041 ttattttatt aaagacgatg aaataagaga gtttttctct aaaaatcatg agggtttttg
     2101 aaacgagttt cttcttgtct tgatactata aaaaacaaag ttatataaca taagacgact
     2161 tatcggaagt agatatgctt gtatattcac agatggtata ataatagagt cgcctatctc
     2221 tcaggcgtca attgacgaag agaggaggtg cattactttg ctaatcattt tcgttcacat
     2281 catagcacca gtcatcagtg gctgtgctgt tgcgtattat acttattggc ttagtaaacg
     2341 caacaaataa ttaataggcg actttataag ccagcatcga aaaaatcccc acactactgc
     2401 aatagtgtgg ggattggtgc attaattgtt aatcattttc gttatataaa ttataacact
     2461 ggttagtaga gaaatgcaaa atgattgaat taatagtaaa tgtattaatg aatactcaca
     2521 cttatacttt taaaatagtt cttcctaaat gttgtccttt taaaagctga tctatcgttt
     2581 tatagaattc ttcaaatcca atttcattgt atagaagtga atttcctata ttccattcat
     2641 ttgctaactt actccatata tcttcacgga tattatgatc aacatataca gaatcaatgc
     2701 caattaattt aatacctcta agaataaacg gtaatatatt agcgttaagt gaatttcctg
     2761 ctacatttcc acatacagta gcaacacctt gataatttag acgttttaaa ccgtataatg
     2821 ttacattact ccccactgta tctaagaaat aatcaaaaat acctttttta agcggtttat
     2881 tatcatcttc aattattatt acttgttttg cacctaattt ttttgcgatt tctatttgct
     2941 tttcttttct tacgatagca gtgatatttt catatccaat tttatgtaaa atttgtatag
     3001 caacactgcc cacaccacct gtagccccag acactaaaat ttcaggttgt gatttgatat
     3061 tcattccata tttttctagt tcaaaaattg ataatgctgc cgtaaaaccg gctgtgccat
     3121 ataccataga ctctttaata gacatttctt ggggaatagg aacaatccac tctccaggca
     3181 cttgtgcata ttctgaaaat ccacctgtat gtgtcacgcc aacatcataa ccagtaacta
     3241 atacattatc gccttcttta aacttatcat tcgaacttga ttcaacaata cctgcaaaat
     3301 ctataccagg aatcatagga taatctctaa ttacaccgcc tttatattgt aaagctagca
     3361 tatccttata atttattgaa gagtatacca cttttactaa tacatcaccc ttcgataaat
     3421 gagattcatc aactttttct actttataac taacatttga tgcacttttt ctcactacta
     3481 ccgcattgaa catttattag ccttctttca caattgtttt gtagaagtat gtttttgttg
     3541 caaaactatt ttcctacaaa acttatcatg atatgataag cgagtcaata ctaatgattt
     3601 aagagaggtt ttagttgtgg aattagataa ttgtataaat tatttgttga gtacttctca
     3661 gaatagagtt tttaaacatt ttaaaagttt attaagtccc tataatatta ctccagcaga
     3721 atatggtgtt ttgaattgct tgattaatag taatttgaat acacctaaag cgattggtaa
     3781 tactttaaat ttagaacctt caacaatatc tggaatatta gataagatgt ccaaaaagga
     3841 tctaataaca cgtcaaactg ataatgaaaa tagaagaact gtgctaataa acagtacaaa
     3901 taaagcaaaa gacttatggc caacattaga aaagaaagcc tatcaactta ataatcatta
     3961 cttcgctaat ttaactaatg aagaaactgt agtgtttaaa aagatattac taaagataaa
     4021 taaaactacg ttttaatttt tacgttataa aaaagttgaa gtgcgaatta taatcgagta
     4081 aatataaatg atagcttagc ttaattatat attaaagcca actatacttt tattcccgaa
     4141 aaacctacta tccaaatttc taagatactt tagcctctat aataaacata ttgtaatata
     4201 atttatgtat tatttaggtt taccctaatc gaacaataaa aaatacttgt aaaatgctat
     4261 tgtcactttg cttgatatat gagaattatt taaccttata aatgagaaaa aagcaacgca
     4321 ctttaaataa gatacgttgc tttttcgatt gatgaacacc tataattaaa ctattcatct
     4381 attatttatg attttttgta tatacaatat ttctagtttg ttaaagagaa ttaagaaaat
     4441 aaatctcgaa aataataaag ggaaaatcag tttttgatat caaaattata catgtcaacg
     4501 ataatacaaa atataataca aactataaga tgttatcagt atttattatg catttagaat
     4561 attaaaattc cttcattaca ctcttggcgg tttcacttat caacttatca tttggcttat
     4621 cacttttatt gtctttattc gtaaaaatga ctaaaacaat aggttcagat tggcccttag
     4681 gataaacaaa agcaacatca tttctagaag catatgttat tgcttgacca cttttatcag
     4741 caaccttata gtcttttgga acaccatctt taattaaagt gtctccgttt ttattattaa
     4801 acattaaatc aagtaagaaa tttttatttt ttttgcttaa ttttccattt gcgataagtt
     4861 tatttaaagt cttgccgaaa gcagcaggcg ttgaagtatc ttttttgctc tttggtgaat
     4921 agtaatttaa ttctatctca tatctaactg gatttgttac tttatctcct agttctttta
     4981 gacgttgttt aacttttttg attccaccga tttcttttat aattttattg tttgctgtat
     5041 tatcactata tgtcattgaa gcctcaataa gttcttttaa agtgatatct tttcctacat
     5101 atttttctaa aataggagaa taagcaacta tatcatcttt gttaatatgt acttttttat
     5161 ttaacttatt ataaggtact tgttctaaca aaatagcact atttatcgct tttgaagtcg
     5221 aagcataggc aaatctctta tctgaattaa attttacttc cttaccactt ttagtattta
     5281 aagcataaac accaatatga gcattatatt ttttttctaa atcatttaac tctttggcat
     5341 gtgaactgtt tgaattacat gcacttaaaa ctaaagcaat tacaattaaa aatattaact
     5401 ttttcaaaat aaaccctccg atattacagt tgtaattttt ataaatcaat aatattacaa
     5461 ttgtaatatt tatgtcaatt gtttattata aatatttgaa agaaggtgtc aaaatggcta
     5521 aattactaat aatgagcgta gtaagctttt gttttatatt tctattgtta gtatttttta
     5581 ggtacatatt aaaacgctat tttaattata gtttaaatta taaagtttgg tatctaacta
     5641 tgcttgctgg attaattcct tttatcccaa ttaaattctc ttttataaaa tttaataatg
     5701 tgaataatca agcgcccaca gttgaaagta agtcacacga tttgaaccat aacataaata
     5761 ccaccaaacc tattcaagag ttcacaacag atatccataa gtttaattgg gattcaattg
     5821 ataatatctg cacagttatt tggatagttt tagttattat tttaagtttt aaatttttga
     5881 aagccttatt atatcttaaa tatttaaaga aacagtcact ttatctaaac gaaaatgaaa
     5941 aaaataaaat agatacgata cttttcaacc atcaatataa aaaaaatatt gtgattcgaa
     6001 aagcagaggc tattcaatct ccaataactt tttggtatgg gaaatatatt attttgattc
     6061 ctagttcata ttttaaaagt gtaattgata aaagactaaa atatataata ctgcatgaat
     6121 atgctcatgc taaaaataga gatactttac atttaattat ctttaatatc ttctctatta
     6181 ttatgagtta caatccatta gtacatattg taaaaagaaa gataattcat gacaatgaag
     6241 tagaagccga tagatttgtc cttaataata ttaacaaaaa tgaatttaaa acttatgcgg
     6301 aatctattat ggactccgta ttaaaaaccc cattttccaa caaaaatata ttaagccatt
     6361 catttaatgg taaaaaatca ttactcaaaa gtagattaat taatataaaa gaagccgatc
     6421 tgaaaaagca gtcaaaatta attctaattt ttatttgtat ttttactttt tttatcatga
     6481 taattcaaag ccagttttta atggggcaat ccttaactga ttataattat aaaaagccct
     6541 tacaaagcga ttaccaaatt ttagatgaaa gtaaaaattt tggttcaaat agtggatctt
     6601 tcgttatgta cagcatgaag aaagacaaat actatattta taatgaaaaa gaaagtagaa
     6661 aaagatattc tcctgattca acttacaaaa tttatttagc actgtttgga cttgaccgtc
     6721 atattataag tgataaaaat tcacgtatgt catggaatca taaacattat cttttcgagt
     6781 cttggaataa ggaacaagat ttaaatacag caatgcaaaa ttcagttaat tggtacttcg
     6841 aacgtattag taatcaaata ccaaagaact atactgcggc tcaactcaag caattaaatt
     6901 atggtaatga aaatttggga agttataaaa gctattggat ggaagatagt ttgaaaatat
     6961 ctaatcttga acaagtaata gtttttaaaa atatgatgga acaaaataac cattttagta
     7021 aaaaagcaaa gaatcaatta tcttcttcat tattgattaa gaaaaatgaa aagtatgaac
     7081 tgtatgggaa aacaggtaca ggtatagtaa acgggaagta taataatggg tggtttgtag
     7141 gttacgtaat tacaaatcat gataagtatt attttgctac acatttatca gatggaaacc
     7201 cgtctgggaa aaatgctgaa ttaataagtg aaaaaatatt aaaaggaatg ggtgttttaa
     7261 atgaccaata agcaagttga aatatctatg gctgaatggg atgttatgaa tataatatgg
     7321 gataaaaaat cagtatcagc taatgaaatt gtagttgaaa ttcaaaaata taaagaagtt
     7381 agtgataaaa cgattagaac attaatcaca agactatata aaaaagagat tataaaacga
     7441 tacaaatcag aaaatattta tttttactca tcaaatatta aagaagacga tattaaaatg
     7501 aaaactgcta aaacctttct taataaactg tatggagggg atatgaaaag tttagtgctg
     7561 aattttgcga aaaatgaaga attaaataac aaagaaattg aagaattgcg agacatttta
     7621 aatgatatta gtaaaaagta attagaggta tgtttcaaac ataatacata tgtaaaccat
     7681 acttgactct tattaaatta gttttgttaa tgacatttaa aatatattat taaagatgag
     7741 agtgtccaga aaataaccat tttctgtaca ctcttgtttt ttgtctaaat aagtaagtat
     7801 tacatagaat tatgtgttca aaaacccaac aaaaaatcta tgttcacaaa agacctcgta
     7861 atcaagttat ggtacactaa aggtgtatat aggaggtctg tattttgaaa ataggttatg
     7921 caagagtttc aactggatta caaaatttga atttacagga ggatcgatta aatacatatg
     7981 gttgtgaaaa gatatttaat gaccatatga gtggttcaaa aagtaagcga cctggtttag
     8041 ataaagcaat tgaatttgcg aggtcaggag atacgattgt tgtttggaga ttagatagac
     8101 taggacggaa catggaggat ttaatcacgt tagttaatga acttaacgaa cgaggtgtga
     8161 gttttcatag tttagaagaa aatataacga tggataaatc aagttctaca ggacaattat
     8221 tatttcattt attcgcagca tttgcagagt ttgaacgtaa tttaatttta gagcgatcat
     8281 cagccggtcg aattgcagca cgtgctagag gccgatatgg aggtagacct gaaaaattaa
     8341 ataaacaaga tttaaactta cttaagacac tttatgataa tggtacgcca attaaaacaa
     8401 ttgcagagca gtggcaagtt tcacgtacaa ctatttatcg ttatctcaat aaattagagg
     8461 caaaagagaa taaaaacaag tagagcaact aatctagctt actataatga atctactaaa
     8521 taattttata tatcattaac atacaaagac tttgattcaa tgtcactcga tgtaaaagag
     8581 acgttctgac agcgtctaaa atctcataat attttcctgt tatgagattt taataataac
     8641 acaagaaaaa agcgtacaaa ttcgtacgct tttttaatat aatacctgtt tcactaatga
     8701 acgttttaag tatcttcatc attaactgaa actacagtaa taatactcgt caacaatatt
     8761 agtatagtta aaatagaaag acttaggact ggcataaccg aactaaaatt atatttgaaa
     8821 tataaaagtg ctaatgaaga gagaaatgta aaaataataa ataccaaaga ccatttttct
     8881 aatttattca ttggcttcac ctctttgaac ttttatataa tcataggaga tatttttact
     8941 acgatttata aaaaataaga agataatcat tattaaagaa acgattaata taatgttgaa
     9001 tcctatagta tcacctaatt cgtttacacc tttgcctaat atcggagata caaagctttg
     9061 tattaataat gaaagagatg cccatatagt aaatgaggtt ctgttgcaaa gttgaattta
     9121 tagtataatt ttaacaaaaa ggagtcttct gtatgaacta tttcagatat aaacaattta
     9181 acaaggatgt tatcactgta gctgttggct actatctaag atatgcattg agttatcgtg
     9241 atatatctga aatattaagg gaacgtggtg taaacgttca tcattcaacg gtctaccgtt
     9301 gggttcaaga atatgcccca attttatatc aaatttggaa gaaaaagcat aaaaaagctt
     9361 attacaaatg gcgtattgat gagacgtaca tcaaaataaa aggaaaatgg agctatttat
     9421 atcgtgccat tgatgcagag ggacatacat tagatatttg gttgcgtaag caacgagata
     9481 atcattcagc atatgcgttt atcaaacgtc tcattaaaca atttggtaaa cctcaaaagg
     9541 taattacaga tcaggcacct tcaacgaagg tagcaatggt taaagtaatt aaagctttta
     9601 aacttaaacc tgactgccat tgtacatcga aatatctgaa taacctcatt gagcaagatc
     9661 accgtcatat taaagtaaga aagacaaggt atcaaagtat caatacagca aagaatactt
     9721 taaaaggtat tgagtgtatt tacgctctat ataaaaagaa ccgcaggtct cttcagatct
     9781 acggattttc gccatgccac gaaattagca tcatgctagc aagttaagcg aacactgaca
     9841 tgataaatta gtggttagct atattttttt actttgcaac agaaccagca tttgttttaa
     9901 tatttgttcc aaagagccat catggctttg acagagctct tcttctatgc aaatgctttt
     9961 aatccgatcc acacgaaaat tcctatattc atttcttagc ctgcaaaacc gattaagtac
    10021 cagttctgtt cataaaaccc cagtgatata ggctctatca ttctgctttc cggttcttgc
    10081 cctcctgatg caggatattg aattgatatt acccttttat tgcagattgc agtctgaatt
    10141 gctgcaataa cgttatccgc caatgtattt ttctgtccag atgtgctgta cacgttaata
    10201 ctgttctcca actcctgtgc atagtttttt tcaccatgct tcaaaataga tttgatttta
    10261 tacatagctg aatcaaaatc ctttataaat gattcatctc catggcaatt taaaaatttc
    10321 cctgctgtaa tcaatgcacc cacttccgcc gctgtaaaca ttaccggcag aagtaggaag
    10381 ccctctacaa gaaaatatcc ttttccggcc tcagatccaa ttggtattcc ggcttcttca
    10441 agtgtccgga tatctctgta aactgtcctt aagcttatat taaatcgctg tgcaatttct
    10501 ttggcaggaa ttattttttt gattgcagct gaataagaat agaggttact ctgttaatcc
    10561 tgttcaaatt ttattcctcc tctgtgactt ccataaaaag tatatcctat gcgttcttaa
    10621 gctagctgct gttagtgctt ctcattgcac cctggttata aaagccatac tcacaaacct
    10681 cttcaccaaa actctttaca tctctaatat agaactctat ctagcgaact tttagaaaag
    10741 atataaaaca tcagagtatg gacagttgcg gatgtacttc agaaaagatt agatgtctaa
    10801 aaagcttgta gttaaagctt tttagacatc taaatctagg tactaaaaca attcatccag
    10861 taaaatataa tattttattt tctcccaatc aggcttgatc cccagtaagt caaaaaatag
    10921 ctcgacatac tgttcttccc cgatatcctc cctgatcgac cggacgcaga aggcaatgtc
    10981 ataccacttg tccgccctgc cgcttctccc aagatcaata aagccactta ctttgccatc
    11041 tttcacaaag atgttgctgt ctcccaggtc gccgtgggaa aagacaagtt cctcttcggg
    11101 cttttccgtc tttaaaaaat catacagctc gcgcggatct ttaaatggag tgtcttcttc
    11161 ccagttttcg caatccacat cggccagatc gttattcagt aagtaatcca attcggctaa
    11221 gcggctgtct aagctattcg tatagggaca atccgatatg tcgatggagt gaaagagcct
    11281 gatgcactcc gcatacagct cgataatctt ttcagggctt tgttcatctt catactcttc
    11341 cgagcaaagg acgccatcgg cctcactcat gagcagattg ctccagccat catgccgttc
    11401 aaagtgcagg acctttggaa caggcagctt tccttccagc catagcatca tgtccttttc
    11461 ccgttccaca tcataggtgg tccctttata ccggctgtcc gtcattttta aatataggtt
    11521 ttcattttct cccaccagct tatatacctt agcaggagac attccttccg tatcttttac
    11581 gcagcggtat ttttcgatca gttttttcaa ttccggtgat attctcattt tagccattta
    11641 ttatttcctt cctcttttct acagtattta aagatacccc aagaagctaa ttataacaag
    11701 acgaactcca attcactgtt ccttgcattc taaaacctta aataccagaa aacagctttt
    11761 tcaaagttgg cgtataacat agtatcgacg gagccgattt tgaaaccaca attatgatag
    11821 aatttacaag ctataaggtt attgtcctgg gtttcaagca ttagtccatg caagttttta
    11881 tgctttgccc attctataga tatattgata agcgcgctgc ctatgccttg ccccctgaaa
    11941 tccttacata cggcgatatc ttctatataa gcgtaccggt tccaattttt tcgcagttta
    12001 acttttccga cgcatttatc gtcttggtag taaagatata ttatcttatc agtattgtca
    12061 atatattcaa ggcaatctgc ctcctcatcc tcttcatcct cttcgtcttg gtagcttttt
    12121 aaatatggcg cttcatagag taattctgta aaggtccaat tctcgttttc atacctcggt
    12181 ataatcttac ctatcacctc aaatggttcg ctgggtttat cgatatcttt caggtgccct
    12241 gctttcattt ctgtaatcac tgttcccgcc tctcttctat atcagcggca tatgtgctat
    12301 ccaggcagcc ggttttacca gtgtattttt tatacatgtc cctggtatat tttgttatat
    12361 tcctatcata ctccggatag gcataatgaa gcctttccgc cacctcaccg gataccgccc
    12421 tgaacaattg atggcataga aataatgctt cccatatgtt ttcataggaa tccatccggt
    12481 aggtggacaa aagtttctcc cacaaatcct cggatatata cctttcaata aacttatagt
    12541 tcttgcctac acttcattta aagcctgttt cgatgccgac cttccatgat atcattctca
    12601 gcagctcatg gcgaacaatc tgattaaaat gatcaatagc aaataaaatt tccttacggc
    12661 acaatccttt aataacataa ggtgttacat tccaaaattc attgcagcaa tcatcatact
    12721 cccttgcgct tggctttctt acatgataat ctatatcagt cggaactatg tcccttttaa
    12781 ttctacaatc tttatcaatt agaaccttta ttaatttatc gccctttagg taattatcta
    12841 actcttccaa gggcaataag gtaagatcaa ttttattgta atcatcaaat agctataata
    12901 gatttagagg taaagaaatt aaatacattg aagagcagaa agattttaca aaagagtatt
    12961 ttaataaaaa tgatggttct gttgcaaagt aaaaaatata gctaatcact aatatatcat
    13021 gtcagtgttc gtttaacttg ctagcatgat gctaatttcg tggcatggcg aaaatccgta
    13081 gatctgaaga gacctgcggt tctttttata tagagcgtaa atacactcaa taccttttaa
    13141 agtattcttt gctgtattga tactttgata ccttgtcttt cttactttaa tatgacggtg
    13201 atcttgctca atgaggttat tcagatattt cgatgtacaa tggcagtcag gtttaagttt
    13261 aaaagcttta attactttaa ccattgctac cttcgttgaa ggtgcctgat ctgtaattac
    13321 cttttgaggt ttaccaaatt gtttaatgag acgtttgata aacgcatatg ctgaatgatt
    13381 atctcgttgc ttacgcaacc aaatatctaa tgtatgtccc tctgtatcaa tggcacgata
    13441 taaatagctc cattttcctt ttattttgat atacgtctca tcaatacgcc atttgtaata
    13501 agctttttta tgctttttct tccaaatttg atataaaatt ggggcatatt cttgaaccca
    13561 acggtagatc gttgaatgat gaacgtttac accacgttct cttaatattt cagatatatc
    13621 acgatagctc aatgcatatc ttagatagta gccaacggct acagtgataa catccttgtt
    13681 aaattgttta tatctgaaat agttcataca gaagactcct ttttgttaaa attatattat
    13741 aaattcaact ttgcaacaga acctcctaac tgtattacca ccttaaaagt agttgcagac
    13801 gcacttccta aatcgtcagc agtgtttaac cacatatcat caacaataat catatgacct
    13861 gttgatgata ctggagcaaa ttctgtcaac ccttcaacta cacctaaaat aaatgcttta
    13921 atctgctcta taaaacccat ttttctcctc cttttaactt atatcagttt ttttaaagta
    13981 tgagaataat ataattacac tgaatataga tgtaacaatt atgataatta aagataatag
    14041 aaatggataa gtattaggta atgttcctct agatatgtct ccaactgcag cccaaggaaa
    14101 taatcctcta tgttcagaat tagcagtcat taaatttatc aaagtaatta ttatggttaa
    14161 aacaattgtg ggaacataat ttttaaaata tatcgacaaa ataattattg gtggagataa
    14221 tatccataat aacactccgc caataacaaa tgtaaagaat gaatcaatta ttaaactctg
    14281 gcttaaccct tgaaaatgca atagcatacc tagcattaaa gttagcaacc atgcaataac
    14341 agatagtgtt tgaatccaca agaataataa tattatttta cttactaaaa aactttctct
    14401 agatataggt ataattaata agttttttaa agtatcttct atatattctc ttccaaacaa
    14461 ataggctatt ataaccccat atagaggagg tccaataatt agcatatgat ataaactgac
    14521 ttcttcaaat aactgtttaa atacaatatt aggagtcggt actttcgtcc gcatactaat
    14581 aaaagaagct acaaccacca taaaaggtgc tacgcatgta cctaaaatac ttattagaaa
    14641 catatatgat ctttttaact taataaattc tgtacggagt agattatcca attgtgccac
    14701 ctcctactaa gtcttcgaaa taagtttcta gattatcttc tatcactctc atctggaaaa
    14761 catcaatatt gtttaatact aataatctat taatttcttg ttgtctatca atatgtgaat
    14821 aaattttaaa ttcgccattt tctttaattt tatagtcata aattccgaag ttagtttcca
    14881 acaaacatgc aactttttct tcatctgata ctgatatact tataaattgt ctgttctttt
    14941 tttttaaatc ttcatacata atttcttcta acaaaactcc gttatgaata atacccacct
    15001 tgtctactaa ctgctctatt tctgacaata tatgacttga aattaaaatg gttatatttc
    15061 tagattgagc cagatcctta atcaactttc taatttcttt tatgccaata ggatctaatc
    15121 cattcgtcgg ctcatcaagt atcaataatt cgggattgtg caataaagct ctcgcaatcc
    15181 ctaaacgttg cttcatacct aaagaataat ttttaaacaa ttttactttt tcagaagcta
    15241 gtcctactat ttctaacact tcttcaattg cattttcttt ttgtatacct aatattttag
    15301 catttatagt taagttctct ttagctgtca aattactata aaaacctggc gtttcaacca
    15361 tagcaccaat attttttaaa atttcagttt tattactttc gaactctttt tcaaatattt
    15421 taatattacc tttcgtaggt ttaattaagc ctaaaagcat tcttatagta gttgttttgc
    15481 ctgcaccatt tcttcctaaa aaaccataaa tttgtccact ttcaacagtt atactcaaat
    15541 tattaactgc tatctgactt ccatattgct ttgttaagtt atttatttca attatattat
    15601 tcaaattttt cacctctggc acctttctta gtttgttgtt acctttatct tacgcgcgat
    15661 tagaaaaggc tgcctttatc tattcttaca aaaacagccg ctaatcttac aaaaatgaaa
    15721 gattggagtt atttaaattg aatggtgaat attgaaccat cgtttaatgt agatgtagca
    15781 cttactttat ggcctaagcg ctttgagatt gtgctgacaa tatataaacc aataccgctt
    15841 gatttctcac ttattctacc gttatagccc gagaaacctt tatcaaagat tttcggtaaa
    15901 tcactcgcat taatgccgat accgttatct cggattgata atttctttgt attttcgtca
    15961 aacgtaatcc acacatcttt gccacgtgca tattttaatg cattgtttaa tatttgctca
    16021 atcataattg atgcccattt ggcatctgtt aatataaccg cttcactttt ctcataatgc
    16081 aactttgttt gatgatgaat aaactgtatc gcataacgtt taatcagtgg tcgaattaat
    16141 tcatctacac tcacttccat aaagaccatg tatgtctttt ggttcatgag tttcaaatag
    16201 ttcagtgcaa gattcgtgta attatcaatt tgtaagactt cattacgcac gttagaaatc
    16261 acgtgttcat caggatcttc aagcagtaac tttgatgctg taatcggtgt cttgatttga
    16321 tgcacccaca ttaaaaaata tgactctaac tcactttggt agttaataaa gtcattacga
    16381 agtttatggt tttcgattct taaatcttcg ttctgttcct gtagtgttta ttctttttta
    16441 aagttcatgt aatggatacc ccagtaaatc attgaaacaa acaatacaat acctagacca
    16501 atcatatatg cttgcatcgg cacattatac atgaataata taaagtagaa taaagcacaa
    16561 gtaaggatga caatataaat ttcacgttgg attgatttca agaaattcat acgtcaccta
    16621 cacgatatcc gacatttttc ttcgtttcga taaaatctgt aagtcctagt ttttgtagct
    16681 ttttgcgtaa acgtgtaatg ttgacagcaa gcgtattgtc atcaatgaag tgttctgatt
    16741 cccagcattt ttcgattaac gcattacgac tgacgaattt gcccttgttc tggaataagc
    16801 tatgcatgat ttgcaattca gtgtgtgtca ggtctatggt ttcttcatta aatttaagct
    16861 ttgctgcatc aagtagtaac tcgcaatcat ctactgttaa attattaact tgagtggtga
    16921 aatcatacgt gcggcgtaat agtgcttgaa tcttagtaat tgtaacagtc atattaaatg
    16981 gctggttctg ttgcaaagta aaaaatatag ctaatcacta atatatcatg tcagtgttcg
    17041 tttaacttgc tagcatgatg ctaatttcgt ggcatgggga aaatccgtag atctgaagag
    17101 acctacggtt ctttttatat agagcgtaaa tacattcaat accttttaaa gtattctttg
    17161 ccgtattgat actttgatat cttgtctttc ttactttaat atgacggtga tcttgctcaa
    17221 tgaggttatt cagatatttc gatgtacaat gacagtcagg tttaagttta aaagctttaa
    17281 ttattttagc cattgctgcc ttcgttgaag gtgcctgatc tgtaactacc ttttgaggct
    17341 taccaaattg tttaatgaga cgtttgataa acgcatatgc tgaatgatta tctcgttgct
    17401 tacgcaacca aatatctaat gtatgtccct ctgtatcaat ggcacgatat aaatagctcc
    17461 attttccttt tattttgata tacgtctcat caatacgcca tttgtaataa gcttttttat
    17521 gctttttctt ccaaatttga tataaaattg gggcatattc ttgaacccaa cggtagatcg
    17581 ttgaatgatg aacgtttaca ccacgttctc ttaatatttc agatatatca cgatagctca
    17641 atgcatatct tagatagtag ccaacggcta cagtgataac atccttgtta aattgtttat
    17701 atctgaaata gttcatacag aagactcctt tttgttaaaa ttatattata aattcaactt
    17761 tgcaacagaa ccgtatttta tgagtacact ctaaattaag gagatgtata atcaatctaa
    17821 aattgtattt ttatactttt gttatataat ctttctactt agagatatat tgtaaaaaaa
    17881 ccaacaaaat gttatattaa cattactatt ttatcgatga gggaggatta aaatgacagc
    17941 ttctatgaga ctcaaataaa cctttttgaa tacaaaacta aattaattca aaaaggcttg
    18001 tccgcaatac acactcatag gatgacttat gtcatttttt atccttcgat aggaataata
    18061 aacgctttca aatactaaaa catcataata aatttttaag tgtttgaaag tgtaatgtga
    18121 atgagacggg agtagcctgt ctcatttttt tgcgtacacg tcctttaaat atacaaggag
    18181 tgtataaata tggaacaata tacaattaaa tttaaccaaa tcaatcataa attgacagat
    18241 ttacgatcac ttaacatcgg tcatctttac gcttaccaat ttgaaaaaat agcacttatt
    18301 gggggtaatg gtactggcaa aaccacatta ctaaatatga ttgctcaaaa aacaaaacca
    18361 gaatctggaa cagttgaaac ggttggcgaa attcaatatt ttgaacagct taacatggat
    18421 gtggaaaatg attttaacac gttagacggt agtttaatga gtgaactcca tatacctatg
    18481 catacaaccg acagtatgag tggtggtgaa aaagcaaaat ataaattagc taatgtcata
    18541 tcaaattata gtccgatatt acttttagat gaacctacaa atcacttgga taaaattggt
    18601 aaagattatc tgaaaaatat tttaaaatat tactatggta ctttaattat agtaagtcat
    18661 gatagagcac ttatagacca aattgctgac acaatttggg atatacaaga agatggcaca
    18721 ataagagtgt ttaaaggtaa ttacacacag tatcaaaatc aatatgaaca agaacagtta
    18781 gaacaacaac gtcaatatga acagtatata agtgaaaaac aaagattgtc ccaagccagt
    18841 aaagctaaac gaaatcaagc gcaacaaatg gcacaagcat catcaaaaca aaaaaacaaa
    18901 agtatagcac cagatcgttt aagtgcatca aaacaaaaag gcacggttga gaaggctgct
    18961 caaaaacaag ctaagcatat tgaaaaaaga atggaacatt tggaagaagt tgaaaaacca
    19021 caaagttatc atgaattcaa tttcccacaa aataaaattt atgatatcca taataattat
    19081 ccaatcattg cacaaaatct aacattggtt aaaggaagtc aaaaactgct aacacaagta
    19141 cgattccaaa taccatatgg caaaaatata gcgctcgtag gtgcaaatgg tgtaggtaag
    19201 acaactttac ttgaagctat ttaccaccaa atagagggaa ttgattgttc tcctaaagtg
    19261 caaatggcat actatcgtca acttgcttat gaagacatgc gtgacgtttc attattgcaa
    19321 tatttaatgg atgaaacgga ttcatcagaa tcattcagta gagctatttt aaataacttg
    19381 ggtttaaatg aagcacttga tcgttcttgt aatgttttga gtggtgggga aagaacgaaa
    19441 ttatcgttag cagtattatt ttcaacgaaa gcgaatatgt taattttgga tgaaccaact
    19501 aattttttag atattaaaac attagaagca ttagaaatgt ttatgaataa atatcctgga
    19561 atcattttgt ttacatcaca tgatacaagg tttgttaaac atgtatcaga taaaaaatgg
    19621 gaattaacag gacaatctct tcatgatata acttaaaaac tatacactaa tttatattga
    19681 atattaggtt catttatatc aatataaaaa atacgttcac aagaaaaata taatagaaat
    19741 aaggatccaa taaaatgact cgacataatg aaattattaa atgtgcagaa aaatatcaat
    19801 tacacatcca acctcaaaca atctcattga atgaatcggg acttgatttt caagttgcat
    19861 ttggaaaaga taaacatgga gtagaatggg ttttgagact accaagaaga cctgacgttt
    19921 ataaacgaac aaaacccgaa aaacaaacgg tagacttctt acagaagaat gtttcatttg
    19981 aaataccgaa gtggaaagta catgcaaaag accttattgc ttacccaaaa cttacaggta
    20041 aacccgcagc cacaatagat ccagaaatac aaaattatgt atgggaaatt gaacacaaac
    20101 cattaccaga aaactttatt aacacattag ctgaaacact cgtagattta cacaacatac
    20161 cagaagaaaa cattaacgtt cagcatataa atatcaaaac catacaagaa ataaaaaatg
    20221 actttcaaag aagaatgaat aaagttaaag aaacttatgg cgtatcagat gaattatgga
    20281 acagatggaa acaatggtta gaaaacgacg aactatggcc tcgacatgcg accatgatac
    20341 atggggactt acatccagga catataatgg tagataacca agcaaacgtc acaggtctca
    20401 tagactggac tgaagcaacc cactccgacc catcaatgga ctttatagga caccatcgtg
    20461 tattcgacga cgaaggatta gagcaactta taacagcata cggtaaagct ggaggtgaaa
    20521 tatggccacg aatgaaagag catataatag aactcaatgc agtattccca atgtttatcg
    20581 ctgagtttgc tatggaatca ggagaatcgg cgtatgaaac gatggcattg aaagagttag
    20641 gtatgaaaga gtagaactta tattaaaaga ggcccatttt aaagacgaag gcaatcctga
    20701 tgaaatttta aaactgcgtt taattagtga tggtctttgg ttttctataa tgtattaaat
    20761 atctggacat ggaacaaatg caacaaatgg aaagaatcgt tttcgaaatt tctaactcct
    20821 taaatcagga ggataaataa acggtcattt tcattgaaag cacttatata aatttcatca
    20881 attttaatac ctaccgtaaa tacatttcat aagtattaaa cagatgatta aaatttttag
    20941 ttaatttaaa tatttatgat agagatgacc ttcaaatgaa cggttctgtt acaaagaaaa
    21001 aatctatatt tatttttagt aagttttaat tatagatatg tacactttga gtacacccta
    21061 accatacaaa aagaattgtt gaaattataa caattaaaac gtatgattag ggtgtatatt
    21121 tattatggag tgaagatgaa tgattatagg ttatgcgaga gtatcatcga tagatcaaaa
    21181 tttagaaaga caattggata atttaaagac gtttggtgtg gagaaaatct ttacagagaa
    21241 acagtcggga aagtcagtgg aaaatagacc tgtatttcaa gaagcactca attttgtcag
    21301 aatgggagat cgattcgttg tggaatctat tgatcgttta ggacgtaact atgatgaaat
    21361 tattgaaact gtgaattatt taaaagaaaa agacgttcag ttaatgatta ccagcttacc
    21421 tatgatgaat gaagtaattg gcaatccatt actggataag tttatgaaag atttaatcat
    21481 tcaaatatta gcaatggttt cagaacaaga gagaaatgaa agtaaacgtc gacaagcgca
    21541 agggattcaa gttgcgaagg aaaaaggcgt atataaaggg cgccctttac tttattcacc
    21601 aaatgctaaa gacccacaga aacgtgttat ttatcatcgc gtggtggaaa tgttagaaga
    21661 aggcaaagcg attagtaaga ttgcgaaaga agttaatatc acaagacaaa cagtttatag
    21721 aattaaacat gataagggat tatcttgata aattgattgt caatgcaaat gagcgtctct
    21781 cacagtgtct caaattccat aacatattat tgaattgaga ttttaataat tatacaagaa
    21841 aaaagagtac gagttcgcag ctttctatat agtaattgtt ttactaataa ggtgttttaa
    21901 aatatattat aatgtaaaaa gtatttgaca tttgtatcaa aaatatttac actcataaat
    21961 gtcaaatact ttttacattt atgaggtgtt ataatgaatt taattccttt tattattatt
    22021 ttaatttttt cttgtttatg gacggctata actaacaaat atttaccttc agaaacatta
    22081 gataaaaaag gacaacaaga tcgatacgat gaaagacaac gtaaaatgtt tattgaaata
    22141 ctggctaaaa gttttatttg gattgtatat tgtatgttat ttacactagt gcttaaattt
    22201 acaggtttgt caccaagtat tgaaggatct tggttttctc aatatccaga aattttcttt
    22261 ataattgtag cactatttct tatgctgttt aattactata ctacaaataa aaaatataca
    22321 tctaaaggtt aaattaatga aaaatagaat tagagaatat agaaaacaaa aaggaatttc
    22381 tcaagaaact ttaagtaaag aattaaaagt gtctaggcaa actattaatg caatagaaaa
    22441 caataaatat gatcctacat tgacattagc atttaagttg gcaagattgt ttgatacaac
    22501 tgtggatgaa ttattttctt aaccattcat ttatcacaaa aagagagtgc gaattcgcac
    22561 tctctttttg tgtagtagta ctattaaatt ttgtctcaat aacgaacgtt tataacgcaa
    22621 tcatgatgag agtattaata cagttaatta tttgaaatac tttagtttac ataatcgatg
    22681 attaccagaa gttctcacta tataaaagac actaaaattt tataactttt agtgcctaat
    22741 caattatttt agctaccaaa caaacgactc caaaacccct ttttaggttc cgtttcttca
    22801 ctcttttctt ctatatcact atcattgtca tttagattag ctggaacgtc ttcttttttt
    22861 gcttcttcac cttgtgtact ttcgtcgctt tgacttccag atatatcctt atattgaatc
    22921 tctgtttctt tagtttcttc ctgatctctg ttaatattta caggattagt agtatatgtt
    22981 ttttcttgtg catcaacgtt ttgtctagtg ttagtagatg tatcaaaggg ataattaagg
    23041 tgtttttctt tttctaattg attttctaat ttttgaatct ttttattact ctctaatgcc
    23101 agaacttgct gattttcaag caattttgat ctttcttgca actcttttct gtaaaattca
    23161 attgttgttt catgacgact ttcttgtttt tcaatttgat tatttaaagt atcaatctga
    23221 tttttaagga tttctactat ttgagcatcg cttttcgatt caaaattaat attatccgac
    23281 cctttttttt gtttgtcttc agtagtactt tcaaaaccat atttcttttt attttcattt
    23341 actctttgaa tgattttttc tatatcggta tcttctttaa taaacgaagt gttttcctgt
    23401 tttattgtct ctatattcaa tcgcttaata ttattaaaaa tcgtttgctt actaacccct
    23461 aattcttcac tcaacttttt cacacttttc atatcatcaa ccctttataa aatgtttata
    23521 aacccttgat aaaatattat aagcttataa tgcttaataa taaagtgatt aataactaaa
    23581 aataaacatc catcaacctt tttatcaagg gtttatgaaa ggtttatgat atttatcaag
    23641 ggtttataaa cccttgataa agctatattt tcccttttat aagtttattt aaagtgctat
    23701 aataaactta atataacaaa aaccccaact actggtaata gtcggggttt ggtaataaaa
    23761 cgtttagaaa ctgtttattt atataatttt cgatacttgt attatataat gaataatatc
    23821 ttagtgcaag cacctaaatc attaaataaa tgtaaagcta aataaaaacg ttttattacc
    23881 tcttaccaaa ctaaaatatg gaaagaggtt ttttgtcatg caaaatcaat attttacagt
    23941 gcaagaaaat tacaaagaaa gattttatca aatccctaaa gtattcttta ccagtgaaaa
    24001 ttataaaaat ctaactaatg atatgaaaat agcctatgct atcttacgtg atcgcttaaa
    24061 tttatctatt aaaaatagct gggttgatga agatggtaac atttactttg tttattcaaa
    24121 tgaaaagcta atggaaatct taaattgtaa aaaagaaaag ttaacaaaaa taaaaaaagg
    24181 gttagaaaac gatggtctac tcattcaaaa acgacgtggt ttaaataaac caaatattct
    24241 atatttaatg aaacctattg tcacagaacg tgatatttac aaaatagaaa aagaagaaaa
    24301 cgatgttgaa ccttacggcg agaaggaagt tcgaaaatcg aacgtccaga agttcgaaaa
    24361 tcgaacgtcc agaagttcga aaatcgaacg tccagaagtt cgaaaatcga acactaatga
    24421 tactgacttt aatgacattg actttaatga tactgagaat aatgatatga atgacttgaa
    24481 tgatataaag tacaaaaatg aaattagtaa tcattcaaat cattcaaatc aatttacaca
    24541 taattttgat gataaagaaa tgctattgca agaattccca gaacaactaa ctaattattt
    24601 attaaaatat gattatagag atttagaaat cataaaggct gttattctta aagcaaaaaa
    24661 atcatttaat tcaaggcatg aagatatgca ttacatgtta gaggacattg aggatgaaat
    24721 attaacttct ttaaaaagac ttaaaaaagc tatacatgat aggggagtta aaggccaaaa
    24781 ggaaacaatc aagtcaatgc aagcttattt aatgcaaaca attctaactg aacttgaaga
    24841 aacacatgcc ctttatatgc gccgtaaaaa catgaaacaa tataatatct ttaatcaata
    24901 attcaaatga ttttataaca ctcgaagaga catcaaaata ttccgttaaa tcatctgact
    24961 ttttaactga tgacgacgaa aaaaatcaag aaattgtaag tgatttagaa aaaggtttgt
    25021 atcgaaaacg tatgttaagt tatggtggat tgcttaaaca aaagcataaa attttaaact
    25081 tagacgatgc cgaagatggt aatttgatta atacaagtga tgaagataaa acgacagacg
    25141 aagaaaaaaa gcacattcaa ttaccgcaat ttggaatttc gaaaagcaaa attattattt
    25201 aagacattag tgataactga tgtctttttt tattgttttt ctgtaaaaaa gtgctgtctt
    25261 atttttgtga caaatgctgt atgtagtgtc acaaaagtgt gacactacag ctttgtatga
    25321 tatcacttta aaataactta aaacccttgg aatgtctggc cttgccagat ctatcatttt
    25381 tgaatgatag caaatttccc ttatgctctt acggagattt tagagttaaa ttaaaatttc
    25441 taagtttttg ataagaaaag ccctgcagga atttagaaaa acatggggaa gttttaaagt
    25501 attttatgct aatttttaaa tttgcatgta aatgggcagt atctaaaaaa ttagtcactg
    25561 attttgctga aatttttgtt tgtgaaatta gcatatattt atttggctca tatttgcgtt
    25621 ttaagagact gtatagattt ttaagtacaa aacctatatg atttgcctct aagtcttcaa
    25681 aatgcctctt aaaatccaaa ataaaagtgt ttaatattgt aataaggatt gctattttta
    25741 taaaaggaga gatatcatga agattaaaac tttcgctact tttactcatc gtcaattaga
    25801 taaacaagtt aataggtttt taaagaatga tattcatgta ttagaaattc aaacacacag
    25861 taattggtta tatatttcag ctattgtttt ttatgaggat aaataaggaa catcgtattt
    25921 atgccgaaaa aatttattga tgttgagaag aacccttaac taaacttgca gacgaatgtc
    25981 ggcatagcgt gagctattaa gccgaccatt cgacaagttt tgggattgtt aagggttccg
    26041 aggctcaacg tcaataaaac aattggaata aaatcaacct acagagcatc cagctgcaaa
    26101 tgcagttccg caaactgctt cacatacacc gccggctatt ggatttacga ttgcccatac
    26161 tccacagtag tgagcacatg cataaagtcc agccatacta caagcgaatg ctttgccgtt
    26221 ccatttgaat cctgcatatg ttaccggtct gtttttatca actttttcag ccttatattc
    26281 aacgtaattt ttgttaataa gtatttttcc ctctttgttt tcagtcatac ttcttttttc
    26341 ggcaatgaat tttgtgattt ttttgttgta gttatcatat attgtttcag aaactacaat
    26401 ttcttttgtt ttttcatttt tataagcgtt attagctatg tagccatatg catttttatc
    26461 atttgcttct gtagctagat attttaattt agaatttttg tcttctagct ttattttttt
    26521 aaatccttct tttttcattt gcttttcgaa tttttgcata tcttcatttt tattttgcaa
    26581 ttgttctaga aaacttattt ctttcttggt catttgtgat acttcgatgt ttttgctttt
    26641 caatttttct ttttgatttt ctagtaaaga acttttttgt tcttcatttg cgtaagcatt
    26701 agaaaaattc gcgctaaata ccagtaggaa caaggaaatt attgaaaata attttataat
    26761 tttcatttga tacctccaag ataataagat attttaattg tataagtaag cgctttataa
    26821 aatcaatatt tattttaata tatttataaa catatttttg aaaggagtct attttatgaa
    26881 tgaaaattta gaaaaatata taaaaagttt gccactttta ggtttgttaa ttagtatttt
    26941 gttaattgtt ttattctttt ttattttaga tgttgatgaa gatttattcg tggttttttt
    27001 atactgttta ttgcctttga tagttaattt gtctatttat ggtttttatg tttttgttaa
    27061 aagaaagt
//
