LOCUS       CP030533               19444 bp    DNA     circular BCT 10-OCT-2019
DEFINITION  Staphylococcus aureus strain ER02495.3 plasmid unnamed1, complete
            sequence.
ACCESSION   CP030533
VERSION     CP030533.1
DBLINK      BioProject: PRJNA470993
            BioSample: SAMN09483979
KEYWORDS    .
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 19444)
  AUTHORS   Sullivan,M.J., Altman,D.R., Chacko,K., Cliferri,B., Webster,E.,
            Deikus,G., Lewis,M., Khan,Z., Beckford,C., Rendo,A., Samaroo,F.,
            Sebra,R., Karam-Howlin,R., Southwick,K., Adams,E., Ying,L.,
            Kornblum,J., Factor,S., Danesh Yazdi,M., Dingle,T., Hamula,C.,
            Bashir,A., Schadt,E., Kasarskis,A., Patel,G., Wallach,F., Gibbs,K.
            and van Bakel,H.
  TITLE     Whole genome sequencing to identify and define MRSA outbreaks
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 19444)
  AUTHORS   Sullivan,M.J., Altman,D.R., Chacko,K., Cliferri,B., Webster,E.,
            Deikus,G., Lewis,M., Khan,Z., Beckford,C., Rendo,A., Samaroo,F.,
            Sebra,R., Karam-Howlin,R., Southwick,K., Adams,E., Ying,L.,
            Kornblum,J., Factor,S., Danesh Yazdi,M., Dingle,T., Hamula,C.,
            Bashir,A., Schadt,E., Kasarskis,A., Patel,G., Wallach,F., Gibbs,K.
            and van Bakel,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUN-2018) Genetics and Genomic Sciences, Icahn School
            of Medicine, One Gustave L. Levy Place Box 1498, New York, NY 10029,
            USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.2.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 227.745193738x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 06/29/2018 17:45:39
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            Annotation Method :: Best-placed reference protein set; GeneMarkS+
            Annotation Software revision      :: 4.5
            Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region
            Genes (total)                     :: 3,045
            CDS (total)                       :: 2,963
            Genes (coding)                    :: 2,885
            CDS (coding)                      :: 2,885
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 39 of 78
            Pseudo Genes (incomplete)         :: 37 of 78
            Pseudo Genes (internal stop)      :: 22 of 78
            Pseudo Genes (multiple problems)  :: 19 of 78
            ##Genome-Annotation-Data-END##
            Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..19444
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="ER02495.3"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="unnamed1"
                     /geo_loc_name="USA:New York City"
                     /lat_lon="40.7903114 N 73.9528738 W"
                     /collection_date="2015"
                     /collected_by="Mount Sinai Hospital"
     gene            join(19099..19444,1..2)
                     /locus_tag="DQU98_15115"
     CDS             join(19099..19444,1..2)
                     /locus_tag="DQU98_15115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="QFL19502.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="transcriptional regulator"
     gene            159..251
                     /locus_tag="DQU98_15120"
     CDS             159..251
                     /locus_tag="DQU98_15120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="QFL19483.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(423..1394)
                     /locus_tag="DQU98_15125"
     CDS             complement(423..1394)
                     /locus_tag="DQU98_15125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH:quinone reductase"
                     /protein_id="QFL19484.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFEEFYKTIDQLLKGQHLGRTILKV"
                     /name="NADPH:quinone reductase"
     gene            1518..1937
                     /locus_tag="DQU98_15130"
     CDS             1518..1937
                     /locus_tag="DQU98_15130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="QFL19485.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            complement(2159..2254)
                     /locus_tag="DQU98_15135"
                     /pseudo=""
     CDS             complement(2159..2254)
                     /locus_tag="DQU98_15135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001560862.1"
                     /note="incomplete; partial on complete genome; missing
                     stop; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase domain-containing protein"
                     /name="O-antigen ligase domain-containing protein"
     gene            complement(2463..3308)
                     /locus_tag="DQU98_15140"
     CDS             complement(2463..3308)
                     /locus_tag="DQU98_15140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /protein_id="QFL19486.1"
                     /translation="MKKLIFLIVIALVLSACNSNSSHAKELNDLEKKYNAHIGVYALNT
                     KSGKEVKFNSDKRFAYASTSKAINSAILLEQVPYNKLNKKVHINKDDIVAYSPILEKYV
                     GKDITLKELIEASMTYSDNTANNKIIKEIGGIKKVKQRLKELGDKVTNPVRYEIELNYY
                     SPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKNFLLDLMFNNKNGDTLIKDGVPKDYKV
                     ADKSGQAITYASRNDVAFVYPKGQSEPIVLVIFTNKDNKSDKPNDKLISETAKSVMKEF
                     "
                     /name="penicillin-hydrolyzing class A beta-lactamase BlaZ"
     gene            3415..5172
                     /locus_tag="DQU98_15145"
     CDS             3415..5172
                     /locus_tag="DQU98_15145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactam sensor/signal transducer BlaR1"
                     /protein_id="QFL19487.1"
                     /translation="MAKLLIMSVVSFCFIFLLLVFFRYILKRYFNYSLNYKVWYLTMLA
                     GLIPFIPIKFSFIKFNNVNNQAPTVESKSHDLNHNINTTKPIQEFTTDIHKFNWDSIDN
                     ICTVIWIVLVIILSFKFLKALLYLKYLKKQSLYLNENEKNKIDTILFNHQYKKNIVIRK
                     AEAIQSPITFWYGKYIILIPSSYFKSVIDKRLKYIILHEYAHAKNRDTLHLIIFNIFSI
                     IMSYNPLVHIVKRKIIHDNEVEADRFVLNNINKNEFKTYAESIMDSVLKTPFSNKNILS
                     HSFNGKKSLLKSRLINIKEADLKKQSKLILIFICIFTFFIMIIQSQFLMGQSLTDYNYK
                     KPLQSDYQILDESKNFGSNSGSFVMYSMKKDKYYIYNEKESRKRYSPDSTYKIYLALFG
                     LDRHIISDKNSRMSWNHKHYLFESWNKEQDLNTAMQNSVNWYFERISNQIPKNYTAAQL
                     KQLNYGNENLGSYKSYWMEDSLKISNLEQVIVFKNMMEQNNHFSKKAKNQLSSSLLIKK
                     NEKYELYGKTGTGIVNGKYNNGWFVGYVITNHDKYYFATHLSDGNPSGKNAELISEKIL
                     KGMGVLNDQ"
                     /name="beta-lactam sensor/signal transducer BlaR1"
     gene            5162..5542
                     /gene="blaI"
                     /locus_tag="DQU98_15150"
     ARG             5163..5539
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="98.41"
                     /coverage="100.0"
     gene            5806..6384
                     /locus_tag="DQU98_15155"
     CDS             5806..6384
                     /locus_tag="DQU98_15155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="QFL19489.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEAKENKNK"
                     /name="HTH domain-containing protein"
     gene            complement(6607..6792)
                     /locus_tag="DQU98_15160"
     CDS             complement(6607..6792)
                     /locus_tag="DQU98_15160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QFL19490.1"
                     /translation="MNKLEKWSLVFIIFTFLSSLALLYFKYNFSSVMPVLSLSILTILI
                     LLTSIITVVSVNDEDT"
                     /name="hypothetical protein"
     gene            7054..7260
                     /locus_tag="DQU98_15165"
                     /pseudo=""
     CDS             7054..7260
                     /locus_tag="DQU98_15165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /note="incomplete; partial on complete genome; missing
                     stop; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /name="IS6 family transposase"
     gene            complement(7319..7993)
                     /locus_tag="DQU98_15170"
     CDS             complement(7319..7993)
                     /locus_tag="DQU98_15170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001106057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="QFL19491.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            8467..9933
                     /locus_tag="DQU98_15175"
     CDS             8467..9933
                     /locus_tag="DQU98_15175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002447408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(A)"
                     /protein_id="QFL19492.1"
                     /translation="MEQYTIKFNQINHKLTDLRSLNIGHLYAYQFEKIALIGGNGTGKT
                     TLLNMIAQKTKPESGTVETVGEIQYFEQLNMDVENDFNTLDGSLMSELHIPMHTTDSMS
                     GGEKAKYKLANVISNYSPILLLDEPTNHLDKIGKDYLKNILKYYYGTLIIVSHDRALID
                     QIADTIWDIQEDGTIRVFKGNYTQYQNQYEQEQLEQQRQYEQYISEKQRLSQASKAKRN
                     QAQQMAQASSKQKNKSIAPDRLSASKQKGTVEKAAQKQAKHIEKRMEHLEEVEKPQSYH
                     EFNFPQNKIYDIHNNYPIIAQNLTLVKGSQKLLTQVRFQIPYGKNIALVGANGVGKTTL
                     LEAIYHQIEGIDCSPKVQMAYYRQLAYEDMRDVSLLQYLMDETDSSESFSRAILNNLGL
                     NEALDRSCNVLSGGERTKLSLAVLFSTKANMLILDEPTNFLDIKTLEALEMFMNKYPGI
                     ILFTSHDTRFVKHVSDKKWELTGQSLHDIT"
                     /name="ABC-F type ribosomal protection protein Msr(A)"
     gene            10032..10931
                     /gene="mph(C)"
                     /locus_tag="DQU98_15180"
     ARG             10033..10928
                     /name="mph(C)"
                     /gene="mph(C)"
                     /gene_name="Mph(C) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            11417..12025
                     /locus_tag="DQU98_15185"
     CDS             11417..12025
                     /locus_tag="DQU98_15185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="QFL19494.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEIIETVNYLKEKDVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRV
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDKGLS"
                     /name="recombinase family protein"
     gene            12271..12609
                     /locus_tag="DQU98_15190"
     CDS             12271..12609
                     /locus_tag="DQU98_15190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QFL19495.1"
                     /translation="MNLIPFIIILIFSCLWTAITNKYLPSETLDKKGQQDRYDERQRKM
                     FIEILAKSFIWIVYCMLFTLVLKFTGLSPSIEGSWFSQYPEIFFIIVALFLMLFNYYTT
                     NKKYTSKG"
                     /name="hypothetical protein"
     gene            12614..12799
                     /locus_tag="DQU98_15195"
     CDS             12614..12799
                     /locus_tag="DQU98_15195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011276570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="QFL19496.1"
                     /translation="MKNRIREYRKQKGISQETLSKELKVSRQTINAIENNKYDPTLTLA
                     FKLARLFDTTVDELFS"
                     /name="transcriptional regulator"
     gene            complement(13026..13769)
                     /locus_tag="DQU98_15200"
     CDS             complement(13026..13769)
                     /locus_tag="DQU98_15200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002508633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="QFL19497.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     gene            14195..15178
                     /locus_tag="DQU98_15205"
     CDS             14195..15178
                     /locus_tag="DQU98_15205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="QFL19498.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNK
                     PNILYLMKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSKIERPEVRK
                     SNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNQFTHNFDDKEMLLQEFPE
                     QLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHD
                     RGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication protein"
     gene            15171..15487
                     /locus_tag="DQU98_15210"
                     /pseudo=""
     CDS             15171..15487
                     /locus_tag="DQU98_15210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002483623.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /name="replication protein"
     gene            complement(16351..17043)
                     /locus_tag="DQU98_15215"
     CDS             complement(16351..17043)
                     /locus_tag="DQU98_15215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QFL19499.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVE
                     YKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTA
                     FAAGCSVG"
                     /name="hypothetical protein"
     gene            17153..17347
                     /locus_tag="DQU98_15220"
     CDS             17153..17347
                     /locus_tag="DQU98_15220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QFL19500.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     gene            18463..19080
                     /locus_tag="DQU98_15225"
     CDS             18463..19080
                     /locus_tag="DQU98_15225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017465246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium transporter"
                     /protein_id="QFL19501.1"
                     /translation="MIQTVVAAAVLYIATAVDLLVILLIFFARAKTRKEYRDIYVGQYL
                     GSIILILVSLFLAFVLNYVPEKWILGLLGLIPIYLGIKVAIYDDCEGEKRAKKELNEKG
                     LSKLVGTVAIVTIASCGADNIGLFVPYFVTLSVTNLLLTLFVFLILIFFLVFTAQKLAN
                     IPGIGEIVEKFSRWIMAIIYIALGLFIIIENDTIQTILGFIF"
                     /name="cadmium transporter"
     ARG             8468..9930
                     /name="msr(A)"
                     /gene="msr(A)"
                     /gene_name="ABC-F type ribosomal protection protein Msr(A)"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             3416..5169
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.38"
                     /coverage="100.0"
     ARG             complement(2467..3308)
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             18464..19077
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             8468..9933
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="98.36"
                     /coverage="100.0"
     ARG             10033..10931
                     /name="mphC"
                     /gene="mphC"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="98.66"
                     /coverage="100.0"
     ARG             complement(2464..3308)
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     Typing          15544..15691
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          complement(13027..13769)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          14196..15178
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.593"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          15310..15479
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.605"
                     /coverage="91.0"
                     /evalue="1.04e-65"
ORIGIN
        1 gaaacgagtt tcttcttgtc ttgatactat aaaaaacaaa gttatataac ataagacgac
       61 ttatcggaag tagatatgct tgtatattca cagatggtat aataatagag tcgcctatct
      121 ctcaggcgtc aattgacgaa gagaggaggt gcattacttt gctaatcatt ttcgttcaca
      181 tcatagcacc agtcatcagt ggctgtgctg ttgcgtatta tacttattgg cttagtaaac
      241 gcaacaaata attaataggc gactttataa gccagcatcg aaaaaatccc cacactactg
      301 caatagtgtg gggattggtg cattaattgt taatcatttt cgttatataa attataacac
      361 tggttagtag agaaatgcaa aatgattgaa ttaatagtaa atgtattaat gaatactcac
      421 acttatactt ttaaaatagt tcttcctaaa tgttgtcctt ttaaaagctg atctatcgtt
      481 ttatagaatt cttcaaatcc aatttcattg tatagaagtg aatttcctat attccattca
      541 tttgctaact tactccatat atcttcacgg atattatgat caacatatac agaatcaatg
      601 ccaattaatt taatacctct aagaataaac ggtaatatat tagcgttaag tgaatttcct
      661 gctacatttc cacatacagt agcaacacct tgataattta gacgttttaa accgtataat
      721 gttacattac tccccactgt atctaagaaa taatcaaaaa tacctttttt aagcggttta
      781 ttatcatctt caattattat tacttgtttt gcacctaatt tttttgcgat ttctatttgc
      841 ttttcttttc ttacgatagc agtgatattt tcatatccaa ttttatgtaa aatttgtata
      901 gcaacactgc ccacaccacc tgtagcccca gacactaaaa tttcaggttg tgatttgata
      961 ttcattccat atttttctag ttcaaaaatt gataatgctg ccgtaaaacc ggctgtgcca
     1021 tataccatag actctttaat agacatttct tggggaatag gaacaatcca ctctccaggc
     1081 acttgtgcat attctgaaaa tccacctgta tgtgtcacgc caacatcata accagtaact
     1141 aatacattat cgccttcttt aaacttatca ttcgaacttg attcaacaat acctgcaaaa
     1201 tctataccag gaatcatagg ataatctcta attacaccgc ctttatattg taaagctagc
     1261 atatccttat aatttattga agagtatacc acttttacta atacatcacc cttcgataaa
     1321 tgagattcat caactttttc tactttataa ctaacatttg atgcactttt tctcactact
     1381 accgcattga acatttatta gccttctttc acaattgttt tgtagaagta tgtttttgtt
     1441 gcaaaactat tttcctacaa aacttatcat gatatgataa gcgagtcaat actaatgatt
     1501 taagagaggt tttagttgtg gaattagata attgtataaa ttatttgttg agtacttctc
     1561 agaatagagt ttttaaacat tttaaaagtt tattaagtcc ctataatatt actccagcag
     1621 aatatggtgt tttgaattgc ttgattaata gtaatttgaa tacacctaaa gcgattggta
     1681 atactttaaa tttagaacct tcaacaatat ctggaatatt agataagatg tccaaaaagg
     1741 atctaataac acgtcaaact gataatgaaa atagaagaac tgtgctaata aacagtacaa
     1801 ataaagcaaa agacttatgg ccaacattag aaaagaaagc ctatcaactt aataatcatt
     1861 acttcgctaa tttaactaat gaagaaactg tagtgtttaa aaagatatta ctaaagataa
     1921 ataaaactac gttttaattt ttacgttata aaaaagttga agtgcgaatt ataatcgagt
     1981 aaatataaat gatagcttag cttaattata tattaaagcc aactatactt ttattcccga
     2041 aaaacctact atccaaattt ctaagatact ttagcctcta taataaacat attgtaatat
     2101 aatttatgta ttatttaggt ttaccctaat cgaacaataa aaaatacttg taaaatgcta
     2161 ttgtcacttt gcttgatata tgagaattat ttaaccttat aaatgagaaa aaagcaacgc
     2221 actttaaata agatacgttg ctttttcgat tgatgaacac ctataattaa actattcatc
     2281 tattatttat gattttttgt atatacaata tttctagttt gttaaagaga attaagaaaa
     2341 taaatctcga aaataataaa gggaaaatca gtttttgata tcaaaattat acatgtcaac
     2401 gataatacaa aatataatac aaactataag atgttatcag tatttattat gcatttagaa
     2461 tattaaaatt ccttcattac actcttggcg gtttcactta tcaacttatc atttggctta
     2521 tcacttttat tgtctttatt cgtaaaaatg actaaaacaa taggttcaga ttggccctta
     2581 ggataaacaa aagcaacatc atttctagaa gcatatgtta ttgcttgacc acttttatca
     2641 gcaaccttat agtcttttgg aacaccatct ttaattaaag tgtctccgtt tttattatta
     2701 aacattaaat caagtaagaa atttttattt tttttgctta attttccatt tgcgataagt
     2761 ttatttaaag tcttgccgaa agcagcaggc gttgaagtat cttttttgct ctttggtgaa
     2821 tagtaattta attctatctc atatctaact ggatttgtta ctttatctcc tagttctttt
     2881 agacgttgtt taactttttt gattccaccg atttctttta taattttatt gtttgctgta
     2941 ttatcactat atgtcattga agcctcaata agttctttta aagtgatatc ttttcctaca
     3001 tatttttcta aaataggaga ataagcaact atatcatctt tgttaatatg tactttttta
     3061 tttaacttat tataaggtac ttgttctaac aaaatagcac tatttatcgc ttttgaagtc
     3121 gaagcatagg caaatctctt atctgaatta aattttactt ccttaccact tttagtattt
     3181 aaagcataaa caccaatatg agcattatat tttttttcta aatcatttaa ctctttggca
     3241 tgtgaactgt ttgaattaca tgcacttaaa actaaagcaa ttacaattaa aaatattaac
     3301 tttttcaaaa taaaccctcc gatattacag ttgtaatttt tataaatcaa taatattaca
     3361 attgtaatat tgatgtcaat tgtttattat aaatatttga aagaaggtgt caaaatggct
     3421 aaattactaa taatgagcgt agtaagcttt tgttttatat ttctattgtt agtatttttt
     3481 aggtacatat taaaacgcta ttttaattat agtttaaatt ataaagtttg gtatctaact
     3541 atgcttgctg gattaattcc ttttatccca attaaattct cttttataaa atttaataat
     3601 gtgaataatc aagcgcccac agttgaaagt aagtcacacg atttgaacca taacataaat
     3661 accaccaaac ctattcaaga gttcacaaca gatatccata agtttaattg ggattcaatt
     3721 gataatatct gcacagttat ttggatagtt ttagttatta ttttaagttt taaatttttg
     3781 aaagccttat tatatcttaa atatttaaag aaacagtcac tttatctaaa cgaaaatgaa
     3841 aaaaataaaa tagatacgat acttttcaac catcaatata aaaaaaatat tgtgattcga
     3901 aaagcagagg ctattcaatc tccaataact ttttggtatg ggaaatatat tattttgatt
     3961 cctagttcat attttaaaag tgtaattgat aaaagactaa aatatataat actgcatgaa
     4021 tatgctcatg ctaaaaatag agatacttta catttaatta tctttaatat cttctctatt
     4081 attatgagtt acaatccatt agtacatatt gtaaaaagaa agataattca tgacaatgaa
     4141 gtagaagccg atagatttgt ccttaataat attaacaaaa atgaatttaa aacttatgcg
     4201 gaatctatta tggactccgt attaaaaacc ccattttcca acaaaaatat attaagccat
     4261 tcatttaatg gtaaaaaatc attactcaaa agtagattaa ttaatataaa agaagccgat
     4321 ctgaaaaagc agtcaaaatt aattctaatt tttatttgta tttttacttt ttttatcatg
     4381 ataattcaaa gccagttttt aatggggcaa tccttaactg attataatta taaaaagccc
     4441 ttacaaagcg attaccaaat tttagatgaa agtaaaaatt ttggttcaaa tagtggatct
     4501 ttcgttatgt acagcatgaa gaaagacaaa tactatattt ataatgaaaa agaaagtaga
     4561 aaaagatatt ctcctgattc aacttacaaa atttatttag cactgtttgg acttgaccgt
     4621 catattataa gtgataaaaa ttcacgtatg tcatggaatc ataaacatta tcttttcgag
     4681 tcttggaata aggaacaaga tttaaataca gcaatgcaaa attcagttaa ttggtacttc
     4741 gaacgtatta gtaatcaaat accaaagaac tatactgcgg ctcaactcaa gcaattaaat
     4801 tatggtaatg aaaatttggg aagttataaa agctattgga tggaagatag tttgaaaata
     4861 tctaatcttg aacaagtaat agtttttaaa aatatgatgg aacaaaataa ccattttagt
     4921 aaaaaagcaa agaatcaatt atcttcttca ttattgatta agaaaaatga aaagtatgaa
     4981 ctgtatggga aaacaggtac aggtatagta aacgggaagt ataataatgg gtggtttgta
     5041 ggttacgtaa ttacaaatca tgataagtat tattttgcta cacatttatc agatggaaac
     5101 ccgtctggga aaaatgctga attaataagt gaaaaaatat taaaaggaat gggtgtttta
     5161 aatgaccaat aagcaagttg aaatatctat ggctgaatgg gatgttatga atataatatg
     5221 ggataaaaaa tcagtatcag ctaatgaaat tgtagttgaa attcaaaaat ataaagaagt
     5281 tagtgataaa acgattagaa cattaatcac aagactatat aaaaaagaga ttataaaacg
     5341 atacaaatca gaaaatattt atttttactc atcaaatatt aaagaagacg atattaaaat
     5401 gaaaactgct aaaacctttc ttaataaact gtatggaggg gatatgaaaa gtttagtgct
     5461 gaattttgcg aaaaatgaag aattaaataa caaagaaatt gaagaattgc gagacatttt
     5521 aaatgatatt agtaaaaagt aattagaggt atgtttcaaa cataatacat atgtaaacca
     5581 tacttgactc ttattaaatt agttttgtta atgacattta aaatatatta ttaaagatga
     5641 gagtgtccag aaaataacca ttttctgtac actcttgttt tttgtctaaa taagtaagta
     5701 ttacatagaa ttatgtgttc aaaaacccaa caaaaaatct atgttcacaa aagacctcgt
     5761 aatcaagtta tggtacacta aaggtgtata taggaggtct gtattttgaa aataggttat
     5821 gcaagagttt caactggatt acaaaatttg aatttacagg aggatcgatt aaatacatat
     5881 ggttgtgaaa agatatttaa tgaccatatg agtggttcaa aaagtaagcg acctggttta
     5941 gataaagcaa ttgaatttgc gaggtcagga gatacgattg ttgtttggag attagataga
     6001 ctaggacgga acatggagga tttaatcacg ttagttaatg aacttaacga acgaggtgtg
     6061 agttttcata gtttagaaga aaatataacg atggataaat caagttctac aggacaatta
     6121 ttatttcatt tattcgcagc atttgcagag tttgaacgta atttaatttt agagcgatca
     6181 tcagccggtc gaattgcagc acgtgctaga ggccgatatg gaggtagacc tgaaaaatta
     6241 aataaacaag atttaaactt acttaagaca ctttatgata atggtacgcc aattaaaaca
     6301 attgcagagc agtggcaagt ttcacgtaca actatttatc gttatctcaa taaattagag
     6361 gcaaaagaga ataaaaacaa gtagagcaac taatctagct tactataatg aatctactaa
     6421 ataattttat atatcattaa catacaaaga ctttgattca atgtcactcg atgtaaaaga
     6481 gacgttctga cagcgtctaa aatctcataa tattttcctg ttatgagatt ttaataataa
     6541 cacaagaaaa aagcgtacaa attcgtacgc ttttttaata taatacctgt ttcactaatg
     6601 aacgttttaa gtatcttcat cattaactga aactacagta ataatactcg tcaacaatat
     6661 tagtatagtt aaaatagaaa gacttaggac tggcataacc gaactaaaat tatatttgaa
     6721 atataaaagt gctaatgaag agagaaatgt aaaaataata aataccaaag accatttttc
     6781 taatttattc attggcttca cctctttgaa cttttatata atcataggag atatttttac
     6841 tacgatttat aaaaaataag aagataatca ttattaaaga aacgattaat ataatgttga
     6901 atcctatagt atcacctaat tcgtttacac ctttgcctaa tatcggagat acaaagcttt
     6961 gtattaataa tgaaagagat gcccatatag taaatgaggt tctgttgcaa agttgaattt
     7021 atagtataat tttaacaaaa aggagtcttc tgtatgaact atttcagata taaacaattt
     7081 aacaaggatg ttatcactgt agctgttggc tactatctaa gatatgcatt gagttatcgt
     7141 gatatatctg aaatattaag ggaacgtggt gtaaacgttc atcattcaac ggtctaccgt
     7201 tgggttcaag aatatgcccc aattttatat caaatttgga agaaaaagca taaaaaagct
     7261 ggttctgttg caaagtaaaa aatatagcta atcactaata tatcatgtca gtgttcgttt
     7321 aacttgctag catgatgcta atttcgtggc atggggaaaa tccgtagatc tgaagagacc
     7381 tacggttctt tttatataga gcgtaaatac attcaatacc ttttaaagta ttctttgccg
     7441 tattgatact ttgatatctt gtctttctta ctttaatatg acggtgatct tgctcaatga
     7501 ggttattcag atatttcgat gtacaatgac agtcaggttt aagtttaaaa gctttaatta
     7561 ttttagccat tgctgccttc gttgaaggtg cctgatctgt aactaccttt tgaggcttac
     7621 caaattgttt aatgagacgt ttgataaacg catatgctga atgattatct cgttgcttac
     7681 gcaaccaaat atctaatgta tgtccctctg tatcaatggc acgatataaa tagctccatt
     7741 ttccttttat tttgatatac gtctcatcaa tacgccattt gtaataagct tttttatgct
     7801 ttttcttcca aatttgatat aaaattgggg catattcttg aacccaacgg tagatcgttg
     7861 aatgatgaac gtttacacca cgttctctta atatttcaga tatatcacga tagctcaatg
     7921 catatcttag atagtagcca acggctacag tgataacatc cttgttaaat tgtttatatc
     7981 tgaaatagtt catacagaag actccttttt gttaaaatta tattataaat tcaactttgc
     8041 aacagaaccg tattttatga gtacactcta aattaaggag atgtataatc aatctaaaat
     8101 tgtattttta tacttttgtt atataatctt tctacttaga gatatattgt aaaaaaacca
     8161 acaaaatgtt atattaacat tactatttta tcgatgaagg aggattaaaa tgacagcttc
     8221 tatgagactc aaataaacct ttttgaatac aaaactaaat taattcaaaa aggcttgtcc
     8281 gcaatacaca ctcataggat gacttatgtc attttttatc cttcgatagg aataataaac
     8341 gctttcaaat actaaaacat cataataaat ttttaagtgt ttgaaagtgt aatgtgaatg
     8401 agacgggagt agcctgtctc atttttttgc gtacacgtcc tttaaatata caaggagtgt
     8461 ataaatatgg aacaatatac aattaaattt aaccaaatca atcataaatt gacagattta
     8521 cgatcactta acatcggtca tctttacgct taccaatttg aaaaaatagc acttattggg
     8581 ggtaatggta ctggcaaaac cacattacta aatatgattg ctcaaaaaac aaaaccagaa
     8641 tctggaacag ttgaaacggt tggcgaaatt caatattttg aacagcttaa catggatgtg
     8701 gaaaatgatt ttaacacgtt agacggtagt ttaatgagtg aactccatat acctatgcat
     8761 acaaccgaca gtatgagtgg tggtgaaaaa gcaaaatata aattagctaa tgtcatatca
     8821 aattatagtc cgatattact tttagatgaa cctacaaatc acttggataa aattggtaaa
     8881 gattatctga aaaatatttt aaaatattac tatggtactt taattatagt aagtcatgat
     8941 agagcactta tagaccaaat tgctgacaca atttgggata tacaagaaga tggcacaata
     9001 agagtgttta aaggtaatta cacacagtat caaaatcaat atgaacaaga acagttagaa
     9061 caacaacgtc aatatgaaca gtatataagt gaaaaacaaa gattgtccca agccagtaaa
     9121 gctaaacgaa atcaagcgca acaaatggca caagcatcat caaaacaaaa aaacaaaagt
     9181 atagcaccag atcgtttaag tgcatcaaaa caaaaaggca cggttgagaa ggctgctcaa
     9241 aaacaagcta agcatattga aaaaagaatg gaacatttgg aagaagttga aaaaccacaa
     9301 agttatcatg aattcaattt cccacaaaat aaaatttatg atatccataa taattatcca
     9361 atcattgcac aaaatctaac attggttaaa ggaagtcaaa aactgctaac acaagtacga
     9421 ttccaaatac catatggcaa aaatatagcg ctcgtaggtg caaatggtgt aggtaagaca
     9481 actttacttg aagctattta ccaccaaata gagggaattg attgttctcc taaagtgcaa
     9541 atggcatact atcgtcaact tgcttatgaa gacatgcgtg acgtttcatt attgcaatat
     9601 ttaatggatg aaacggattc atcagaatca ttcagtagag ctattttaaa taacttgggt
     9661 ttaaatgaag cacttgatcg ttcttgtaat gttttgagtg gtggggaaag aacgaaatta
     9721 tcgttagcag tattattttc aacgaaagcg aatatgttaa ttttggatga accaactaat
     9781 tttttagata ttaaaacatt agaagcatta gaaatgttta tgaataaata tcctggaatc
     9841 attttgttta catcacatga tacaaggttt gttaaacatg tatcagataa aaaatgggaa
     9901 ttaacaggac aatctcttca tgatataact taaaaactat acactaattt atattgaata
     9961 ttaggttcat ttatatcaat ataaaaaata cgttcacaag aaaaatataa tagaaataag
    10021 gatccaataa aatgactcga cataatgaaa ttattaaatg tgcagaaaaa tatcaattac
    10081 acatccaacc tcaaacaatc tcattgaatg aatcgggact tgattttcaa gttgcatttg
    10141 gaaaagataa acatggagta gaatgggttt tgagactacc aagaagacct gacgtttata
    10201 aacgaacaaa acccgaaaaa caaacggtag acttcttaca gaagaatgtt tcatttgaaa
    10261 taccgaagtg gaaagtacat gcaaaagacc ttattgctta cccaaaactt acaggtaaac
    10321 ccgcagccac aatagatcca gaaatacaaa attatgtatg ggaaattgaa cacaaaccat
    10381 taccagaaaa ctttattaac acattagctg aaacactcgt agatttacac aacataccag
    10441 aagaaaacat taacgttcag catataaata tcaaaaccat acaagaaata aaaaatgact
    10501 ttcaaagaag aatgaataaa gttaaagaaa cttatggcgt atcagatgaa ttatggaaca
    10561 gatggaaaca atggttagaa aacgacgaac tatggcctcg acatgcgacc atgatacatg
    10621 gggacttaca tccaggacat ataatggtag ataaccaagc aaacgtcaca ggtctcatag
    10681 actggactga agcaacccac tccgacccat caatggactt tataggacac catcgtgtat
    10741 tcgacgacga aggattagag caacttataa cagcatacgg taaagctgga ggtgaaatat
    10801 ggccacgaat gaaagagcat ataatagaac tcaatgcagt attcccaatg tttatcgctg
    10861 agtttgctat ggaatcagga gaatcggcgt atgaaacgat ggcattgaaa gagttaggta
    10921 tgaaagagta gaacttatat taaaagaggc ccattttaaa gacgaaggca atcctgatga
    10981 aattttaaaa ctgcgtttaa ttagtgatgg tctttggttt tctataatgt attaaatatc
    11041 tggacatgga acaaatgcaa caaatggaaa gaatcgtttt cgaaatttct aactccttaa
    11101 atcaggagga taaataaacg gtcattttca ttgaaagcac ttatataaat ttcatcaatt
    11161 ttaataccta ccgtaaatac atttcataag tattaaacag atgattaaaa tttttagtta
    11221 atttaaatat ttatgataga gatgaccttc aaatgaacgg ttctgttaca aagaaaaaat
    11281 ctatatttat ttttagtaag ttttaattat agatatgtac actttgagta caccctaacc
    11341 atacaaaaag aattgttgaa attataacaa ttaaaacgta tgattagggt gtatatttat
    11401 tatggagtga agatgaatga ttataggtta tgcgagagta tcatcgatag atcaaaattt
    11461 agaaagacaa ttggataatt taaagacgtt tggtgtggag aaaatcttta cagagaaaca
    11521 gtcgggaaag tcagtggaaa atagacctgt atttcaagaa gcactcaatt ttgtcagaat
    11581 gggagatcga ttcgttgtgg aatctattga tcgtttagga cgtaactatg atgaaattat
    11641 tgaaactgtg aattatttaa aagaaaaaga cgttcagtta atgattacca gcttacctat
    11701 gatgaatgaa gtaattggca atccattact ggataagttt atgaaagatt taatcattca
    11761 aatattagca atggtttcag aacaagagag aaatgaaagt aaacgtcgac aagcgcaagg
    11821 gattcaagtt gcgaaggaaa aaggcgtata taaagggcgc cctttacttt attcaccaaa
    11881 tgctaaagac ccacagaaac gtgttattta tcatcgcgtg gtggaaatgt tagaagaagg
    11941 caaagcgatt agtaagattg cgaaagaagt taatatcaca agacaaacag tttatagaat
    12001 taaacatgat aagggattat cttgataaat tgattgtcaa tgcaaatgag cgtctctcac
    12061 agtgtctcaa attccataac atattattga attgagattt taataattat acaagaaaaa
    12121 agagtacgag ttcgcagctt tctatatagt aattgtttta ctaataaggt gttttaaaat
    12181 atattataat gtaaaaagta tttgacattt gtatcaaaaa tatttacact cataaatgtc
    12241 aaatactttt tacatttatg aggtgttata atgaatttaa ttccttttat tattatttta
    12301 attttttctt gtttatggac ggctataact aacaaatatt taccttcaga aacattagat
    12361 aaaaaaggac aacaagatcg atacgatgaa agacaacgta aaatgtttat tgaaatactg
    12421 gctaaaagtt ttatttggat tgtatattgt atgttattta cactagtgct taaatttaca
    12481 ggtttgtcac caagtattga aggatcttgg ttttctcaat atccagaaat tttctttata
    12541 attgtagcac tatttcttat gctgtttaat tactatacta caaataaaaa atatacatct
    12601 aaaggttaaa ttaatgaaaa atagaattag agaatataga aaacaaaaag gaatttctca
    12661 agaaacttta agtaaagaat taaaagtgtc taggcaaact attaatgcaa tagaaaacaa
    12721 taaatatgat cctacattga cattagcatt taagttggca agattgtttg atacaactgt
    12781 ggatgaatta ttttcttaac cattcattta tcacaaaaag agagtgcgaa ttcgcactct
    12841 ctttttgtgt agtagtacta ttaaattttg tctcaataac gaacgtttat aacgcaatca
    12901 tgatgagagt attaatacag ttaattattt gaaatacttt agtttacata atcgatgatt
    12961 accagaagtt ctcactatat aaaagacact aaaattttat aacttttagt gcctaatcaa
    13021 ttattttagc taccaaacaa acgactccaa aacccctttt taggttccgt ttcttcactc
    13081 ttttcttcta tatcactatc attgtcattt agattagctg gaacgtcttc tttttttgct
    13141 tcttcacctt gtgtactttc gtcgctttga cttccagata tatccttata ttgaatctct
    13201 gtttctttag tttcttcctg atctctgtta atatttacag gattagtagt atatgttttt
    13261 tcttgtgcat caacgttttg tctagtgtta gtagatgtat caaagggata attaaggtgt
    13321 ttttcttttt ctaattgatt ttctaatttt tgaatctttt tattactctc taatgccaga
    13381 acttgctgat tttcaagcaa ttttgatctt tcttgcaact cttttctgta aaattcaatt
    13441 gttgtttcat gacgactttc ttgtttttca atttgattat ttaaagtatc aatctgattt
    13501 ttaaggattt ctactatttg agcatcgctt ttcgattcaa aattaatatt atccgaccct
    13561 tttttttgtt tgtcttcagt agtactttca aaaccatatt tctttttatt ttcatttact
    13621 ctttgaatga ttttttctat atcggtatct tctttaataa acgaagtgtt ttcctgtttt
    13681 attgtctcta tattcaatcg cttaatatta ttaaaaatcg tttgcttact aacccctaat
    13741 tcttcactca actttttcac acttttcata tcatcaaccc tttataaaat gtttataaac
    13801 ccttgataaa atattataag cttataatgc ttaataataa agtgattaat aaataaaaat
    13861 aaacatccat caaccttttt atcaagggtt tatgaaaggt ttatgatatt tatcaagggt
    13921 ttataaaccc ttgataaagc tatattttcc cttttataag tttatttaaa gtgctataat
    13981 aaacttaata taacaaaaac cccaactact ggtaatagtc ggggtttggt aataaaacgt
    14041 ttagaaactg tttatttata taattttcga tacttgtatt atataatgaa taatatctta
    14101 gtgcaagcac ctaaatcatt aaataaatgt aaagctaaat aaaaacgttt tattacctct
    14161 taccaaacta aaatatggaa agaggttttt tgtcatgcaa aatcaatatt ttacagtgca
    14221 agaaaattac aaagaaagat tttatcaaat ccctaaagta ttctttacca gtgaaaatta
    14281 taaaaatcta actaatgata tgaaaatagc ctatgctatc ttacgtgatc gcttaaattt
    14341 atctattaaa aatagctggg ttgatgaaga tggtaacatt tactttgttt attcaaatga
    14401 aaagctaatg gaaatcttaa attgtaaaaa agaaaagtta acaaaaataa aaaaagggtt
    14461 agaaaacgat ggtctactca ttcaaaaacg acgtggttta aataaaccaa atattctata
    14521 tttaatgaaa cctattgtca cagaacgtga tatttacaaa atagaaaaag aagaaaacga
    14581 tgttgaacct tacggcgaga aggaagttcg aaaatcgaac gtccagaagt tcgaaaatcg
    14641 aacgtccaga agttcgaaaa tcgaacgtcc agaagttcga aaatcgaaca ctaatgatac
    14701 tgactttaat gacattgact ttaatgatac tgagaataat gatatgaatg acttgaatga
    14761 tataaagtac aaaaatgaaa ttagtaatca ttcaaatcat tcaaatcaat ttacacataa
    14821 ttttgatgat aaagaaatgc tattgcaaga attcccagaa caactaacta attatttatt
    14881 aaaatatgat tatagagatt tagaaatcat aaaggctgtt attcttaaag caaaaaaatc
    14941 atttaattca aggcatgaag atatgcatta catgttagag gacattgagg atgaaatatt
    15001 aacttcttta aaaagactta aaaaagctat acatgatagg ggagttaaag gccaaaagga
    15061 aacaatcaag tcaatgcaag cttatttaat gcaaacaatt ctaactgaac ttgaagaaac
    15121 acatgccctt tatatgcgcc gtaaaaacat gaaacaatat aatatcttta atcaataatt
    15181 caaatgattt tataacactc gaagagacat caaaatattc cgttaaatca tctgactttt
    15241 taactgatga cgacgaaaaa aatcaagaaa ttgtaagtga tttagaaaaa ggtttgtatc
    15301 gaaaacgtat gttaagttat ggtggattgc ttaaacaaaa gcataaaatt ttaaacttag
    15361 acgatgccga agatggtaat ttgattaata caagtgatga agataaaacg acagacgaag
    15421 aaaaaaagca cattcaatta ccgcaatttg gaatttcgaa aagcaaaatt attatttaag
    15481 acattagtga taactgatgt ctttttttat tgtttttctg taaaaaagtg ctgtcttatt
    15541 tttgtgacaa atgctgtatg tagtgtcaca aaagtgtgac actacagctt tgtatgatat
    15601 cactttaaaa taacttaaaa cccttggaat gtctggcctt gccagatcta tcatttttga
    15661 atgatagcaa atttccctta tgctcttacg gagattttag agttaaatta aaatttctaa
    15721 gtttttgata agaaaagccc tgcaggaatt tagaaaaaca tggggaagtt ttaaagtatt
    15781 ttatgctaat ttttaaattt gcatgtaaat gggcagtatc taaaaaatta gtcactgatt
    15841 ttgctgaaat ttttgtttgt gaaattagca tatatttatt tggctcatat ttgcgtttta
    15901 agagactgta tagattttta agtacaaaac ctatatgatt tgcctctaag tcttcaaaat
    15961 gcctcttaaa atccaaaata aaagtgttta atattgtaat aaggattgct atttttataa
    16021 aaggagagat atcatgaaga ttaaaacttt cgctactttt actcatcgtc aattagataa
    16081 acaagttaat aggtttttaa agaatgatat tcatgtatta gaaattcaaa cacacagtaa
    16141 ttggttatat atttcagcta ttgtttttta tgaggataaa taaggaacat cgtatttatg
    16201 ccgaaaaaat ttattgatgt tgagaagaac ccttaactaa acttgcagac gaatgtcggc
    16261 atagcgtgag ctattaagcc gaccattcga caagttttgg gattgttaag ggttccgagg
    16321 ctcaacgtca ataaaacaat tggaataaaa tcaacctaca gagcatccag ctgcaaatgc
    16381 agttccgcaa actgcttcac atacaccgcc ggctattgga tttacgattg cccatactcc
    16441 acagtagtga gcacatgcat aaagtccagc catactacaa gcgaatgctt tgccgttcca
    16501 tttgaatcct gcatatgtta ccggtctgtt tttatcaact ttttcagcct tatattcaac
    16561 gtaatttttg ttaataagta tttttccctc tttgttttca gtcatacttc ttttttcggc
    16621 aatgaatttt gtgatttttt tgttgtagtt atcatatatt gtttcagaaa ctacaatttc
    16681 ttttgttttt tcatttttat aagcgttatt agctatgtag ccatatgcat ttttatcatt
    16741 tgcttctgta gctagatatt ttaatttaga atttttgtct tctagcttta tttttttaaa
    16801 tccttctttt ttcatttgct tttcgaattt ttgcatatct tcatttttat tttgcaattg
    16861 ttctagaaaa cttatttctt tcttggtcat ttgtgatact tcgatgtttt tgcttttcaa
    16921 tttttctttt tgattttcta gtaaagaact tttttgttct tcatttgcgt aagcattaga
    16981 aaaattcgcg ctaaatacca gtaggaacaa ggaaattatt gaaaataatt ttataatttt
    17041 catttgatac ctccaagata ataagatatt ttaattgtat aagtaagcgc tttataaaat
    17101 caatatttat tttaatatat ttataaacat atttttgaaa ggagtctatt ttatgaatga
    17161 aaatttagaa aaatatataa aaagtttgcc acttttaggt ttgttaatta gtattttgtt
    17221 aattgtttta ttctttttta ttttagatgt tgatgaagat ttattcgtgg tttttttata
    17281 ctgtttattg cctttgatag ttaatttgtc tatttatggt ttttatgttt ttgttaaaag
    17341 aaagtaagat tatgaataat tttgttttta atttgtatgc tttgaggggg ttggaaaacg
    17401 gtaggtgtat agattagatt tcttgttttt ttgaaacgag tgtgaacgag tttcttcttg
    17461 tcttgatttt tgataaaaac gccctacagg aatttagaaa aacgtgggga agttttaaag
    17521 aattttatgc taatttttaa tttgcatgta aatgggcagt gtctaaaaat agttattgtt
    17581 tttgctcaaa tttttgtttt tgaaaatagc atatatttat ttggctcata tttgcgtttt
    17641 aaaagcatat ataagtttta gatataaaac tatatgaatc acccctaaat ctttaaaatg
    17701 ccctcttaaa attcaaaata agggcataaa aaataaaagc taccccagat aaagtgaggt
    17761 agctttttct ttcatacggt ctatttattt ttctttcgac gccgtatcgt cgatgtaatt
    17821 caaaaaagtt atgggctata aatctacatc actttttcaa gaatgtagta gcaatattca
    17881 acgcaaatta atttttataa ctgctcggaa tatctcaagc cgtttcttta attttgaaat
    17941 aaaaaaatcg acgaaggtcg attacgtttt tgcacatgtc gatttatccg acgtataagt
    18001 gcgcccttac gggatttaac tagattataa cgacgaattt tagacctgta aagcaataac
    18061 aattaggtct accaggtaga taaagtgtac aaagtagaac cgaaaaagtt atttattttg
    18121 aagatttttc gtagatataa tttgctaata aacttcctaa aactgaataa agaaaaatag
    18181 ttaaactcat gtaatcactc cataattctg aagtgtctcc atgtctacgc atagacacgc
    18241 atttatgccg aaaaaattta ttgatgttga gaagaaccct taactaaact tgcagacgaa
    18301 tgtcggcata gcgtgagcta ttaagccgac cattcgacaa gttttgggat tgttaagggt
    18361 tccgaggctc aacgtcaata aagcaattgg aataaagcac ctatgattat ttaaaaatat
    18421 aagttataat acattcaaaa atatttttga atgaggtgta ttatgattca aacggttgtt
    18481 gctgctgctg ttctttatat tgctacagca gttgatttat tagtaatttt attaatattt
    18541 tttgctagag caaagactag aaaagaatat agagatattt atgttggtca atatttaggg
    18601 tctattattt taatattagt tagtttgttt ttagcttttg tattaaatta tgttccagaa
    18661 aagtggatat taggtttatt gggtttaata ccaatttatc ttggaattaa agtggctatt
    18721 tatgatgatt gtgaaggaga aaagagagct aaaaaagaat tgaatgaaaa aggattgtct
    18781 aaattagttg gtacggttgc aattgttacg atagcaagtt gtggcgccga taatattggt
    18841 ttatttgttc cgtattttgt gacattaagt gttactaatt tattacttac tctgtttgtc
    18901 tttttaattt taattttctt cttggtgttt actgcacaaa aattagctaa tattccagga
    18961 attggagaaa ttgttgagaa atttagtcgt tggattatgg ctattattta tatagcttta
    19021 ggtttattta ttattattga aaatgacact attcaaacaa ttttaggatt tatattttaa
    19081 tttagggtgt gattttatat gagttatgaa aatacttgtg atgtgatctg tgtacatgag
    19141 gataaagtta acaatgcttt aagtttttta gaagatgata aatctaagaa attacttaac
    19201 attttagaaa aaatttgtga tgagaagaaa ttgaaaatca tattatcttt gattaaagaa
    19261 gatgagttgt gtgtttgtga tatttctttg atattgaaaa tgagtgttgc ttcaacttca
    19321 catcatttaa ggcttttata taaaaatgag gtacttgatt tttataaaga tggaaagatg
    19381 gcatattatt ttattaaaga cgatgaaata agagagtttt tctctaaaaa tcatgagggt
    19441 tttt
//
