LOCUS       CP030528               20067 bp    DNA     circular BCT 10-OCT-2019
DEFINITION  Staphylococcus aureus strain ER02703.3 plasmid unnamed2, complete
            sequence.
ACCESSION   CP030528
VERSION     CP030528.1
DBLINK      BioProject: PRJNA470993
            BioSample: SAMN09483987
KEYWORDS    .
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 20067)
  AUTHORS   Sullivan,M.J., Altman,D.R., Chacko,K., Cliferri,B., Webster,E.,
            Deikus,G., Lewis,M., Khan,Z., Beckford,C., Rendo,A., Samaroo,F.,
            Sebra,R., Karam-Howlin,R., Southwick,K., Adams,E., Ying,L.,
            Kornblum,J., Factor,S., Danesh Yazdi,M., Dingle,T., Hamula,C.,
            Bashir,A., Schadt,E., Kasarskis,A., Patel,G., Wallach,F., Gibbs,K.
            and van Bakel,H.
  TITLE     Whole genome sequencing to identify and define MRSA outbreaks
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 20067)
  AUTHORS   Sullivan,M.J., Altman,D.R., Chacko,K., Cliferri,B., Webster,E.,
            Deikus,G., Lewis,M., Khan,Z., Beckford,C., Rendo,A., Samaroo,F.,
            Sebra,R., Karam-Howlin,R., Southwick,K., Adams,E., Ying,L.,
            Kornblum,J., Factor,S., Danesh Yazdi,M., Dingle,T., Hamula,C.,
            Bashir,A., Schadt,E., Kasarskis,A., Patel,G., Wallach,F., Gibbs,K.
            and van Bakel,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUN-2018) Genetics and Genomic Sciences, Icahn School
            of Medicine, One Gustave L. Levy Place Box 1498, New York, NY 10029,
            USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.2.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 209.479092341x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 06/29/2018 17:44:27
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            Annotation Method :: Best-placed reference protein set; GeneMarkS+
            Annotation Software revision      :: 4.5
            Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region
            Genes (total)                     :: 3,084
            CDS (total)                       :: 3,002
            Genes (coding)                    :: 2,924
            CDS (coding)                      :: 2,924
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 78
            Pseudo Genes (ambiguous residues) :: 0 of 78
            Pseudo Genes (frameshifted)       :: 42 of 78
            Pseudo Genes (incomplete)         :: 35 of 78
            Pseudo Genes (internal stop)      :: 20 of 78
            Pseudo Genes (multiple problems)  :: 18 of 78
            ##Genome-Annotation-Data-END##
            Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..20067
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="ER02703.3"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="unnamed2"
                     /geo_loc_name="USA:New York City"
                     /lat_lon="40.7903114 N 73.9528738 W"
                     /collection_date="2015"
                     /collected_by="Mount Sinai Hospital"
     gene            complement(317..1009)
                     /locus_tag="DQV06_15310"
     CDS             complement(317..1009)
                     /locus_tag="DQV06_15310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QFK79011.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVE
                     YKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTA
                     FAAGCSVG"
                     /name="hypothetical protein"
     gene            1119..1313
                     /locus_tag="DQV06_15315"
     CDS             1119..1313
                     /locus_tag="DQV06_15315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QFK79012.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     gene            2429..3046
                     /locus_tag="DQV06_15320"
     CDS             2429..3046
                     /locus_tag="DQV06_15320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017465246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium transporter"
                     /protein_id="QFK79013.1"
                     /translation="MIQTVVAAAVLYIATAVDLLVILLIFFARAKTRKEYRDIYVGQYL
                     GSIILILVSLFLAFVLNYVPEKWILGLLGLIPIYLGIKVAIYDDCEGEKRAKKELNEKG
                     LSKLVGTVAIVTIASCGADNIGLFVPYFVTLSVTNLLLTLFVFLILIFFLVFTAQKLAN
                     IPGIGEIVEKFSRWIMAIIYIALGLFIIIENDTIQTILGFIF"
                     /name="cadmium transporter"
     gene            3065..3412
                     /locus_tag="DQV06_15325"
     CDS             3065..3412
                     /locus_tag="DQV06_15325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="QFK79014.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="transcriptional regulator"
     gene            3569..3661
                     /locus_tag="DQV06_15330"
     CDS             3569..3661
                     /locus_tag="DQV06_15330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="QFK79015.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(3833..4804)
                     /locus_tag="DQV06_15335"
     CDS             complement(3833..4804)
                     /locus_tag="DQV06_15335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH:quinone reductase"
                     /protein_id="QFK79016.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFEEFYKTIDQLLKGQHLGRTILKV"
                     /name="NADPH:quinone reductase"
     gene            4928..5347
                     /locus_tag="DQV06_15340"
     CDS             4928..5347
                     /locus_tag="DQV06_15340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="QFK79017.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     gene            complement(5569..5664)
                     /locus_tag="DQV06_15345"
                     /pseudo=""
     CDS             complement(5569..5664)
                     /locus_tag="DQV06_15345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001560862.1"
                     /note="incomplete; partial on complete genome; missing
                     stop; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase domain-containing protein"
                     /name="O-antigen ligase domain-containing protein"
     gene            complement(5873..6718)
                     /locus_tag="DQV06_15350"
     CDS             complement(5873..6718)
                     /locus_tag="DQV06_15350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /protein_id="QFK79018.1"
                     /translation="MKKLIFLIVIALVLSACNSNSSHAKELNDLEKKYNAHIGVYALNT
                     KSGKEVKFNSDKRFAYASTSKAINSAILLEQVPYNKLNKKVHINKDDIVAYSPILEKYV
                     GKDITLKELIEASMTYSDNTANNKIIKEIGGIKKVKQRLKELGDKVTNPVRYEIELNYY
                     SPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKNFLLDLMFNNKNGDTLIKDGVPKDYKV
                     ADKSGQAITYASRNDVAFVYPKGQSEPIVLVIFTNKDNKSDKPNDKLISETAKSVMKEF
                     "
                     /name="penicillin-hydrolyzing class A beta-lactamase BlaZ"
     gene            6825..8582
                     /locus_tag="DQV06_15355"
     CDS             6825..8582
                     /locus_tag="DQV06_15355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactam sensor/signal transducer BlaR1"
                     /protein_id="QFK79019.1"
                     /translation="MAKLLIMSVVSFCFIFLLLVFFRYILKRYFNYSLNYKVWYLTMLA
                     GLIPFIPIKFSFIKFNNVNNQAPTVESKSHDLNHNINTTKPIQEFTTDIHKFNWDSIDN
                     ICTVIWIVLVIILSFKFLKALLYLKYLKKQSLYLNENEKNKIDTILFNHQYKKNIVIRK
                     AEAIQSPITFWYGKYIILIPSSYFKSVIDKRLKYIILHEYAHAKNRDTLHLIIFNIFSI
                     IMSYNPLVHIVKRKIIHDNEVEADRFVLNNINKNEFKTYAESIMDSVLKTPFSNKNILS
                     HSFNGKKSLLKSRLINIKEADLKKQSKLILIFICIFTFFIMIIQSQFLMGQSLTDYNYK
                     KPLQSDYQILDESKNFGSNSGSFVMYSMKKDKYYIYNEKESRKRYSPDSTYKIYLALFG
                     LDRHIISDKNSRMSWNHKHYLFESWNKEQDLNTAMQNSVNWYFERISNQIPKNYTAAQL
                     KQLNYGNENLGSYKSYWMEDSLKISNLEQVIVFKNMMEQNNHFSKKAKNQLSSSLLIKK
                     NEKYELYGKTGTGIVNGKYNNGWFVGYVITNHDKYYFATHLSDGNPSGKNAELISEKIL
                     KGMGVLNDQ"
                     /name="beta-lactam sensor/signal transducer BlaR1"
     gene            8572..8952
                     /gene="blaI"
                     /locus_tag="DQV06_15360"
     ARG             8573..8949
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="98.41"
                     /coverage="100.0"
     gene            9216..9794
                     /locus_tag="DQV06_15365"
     CDS             9216..9794
                     /locus_tag="DQV06_15365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="QFK79021.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEAKENKNK"
                     /name="HTH domain-containing protein"
     gene            complement(10017..10202)
                     /locus_tag="DQV06_15370"
     CDS             complement(10017..10202)
                     /locus_tag="DQV06_15370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QFK79022.1"
                     /translation="MNKLEKWSLVFIIFTFLSSLALLYFKYNFSSVMPVLSLSILTILI
                     LLTSIITVVSVNDEDT"
                     /name="hypothetical protein"
     gene            10464..11138
                     /locus_tag="DQV06_15375"
     CDS             10464..11138
                     /locus_tag="DQV06_15375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="QFK79023.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(11352..12026)
                     /locus_tag="DQV06_15380"
     CDS             complement(11352..12026)
                     /locus_tag="DQV06_15380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001106057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="QFK79024.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6 family transposase"
     gene            12500..13966
                     /locus_tag="DQV06_15385"
     CDS             12500..13966
                     /locus_tag="DQV06_15385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002447408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(A)"
                     /protein_id="QFK79025.1"
                     /translation="MEQYTIKFNQINHKLTDLRSLNIGHLYAYQFEKIALIGGNGTGKT
                     TLLNMIAQKTKPESGTVETVGEIQYFEQLNMDVENDFNTLDGSLMSELHIPMHTTDSMS
                     GGEKAKYKLANVISNYSPILLLDEPTNHLDKIGKDYLKNILKYYYGTLIIVSHDRALID
                     QIADTIWDIQEDGTIRVFKGNYTQYQNQYEQEQLEQQRQYEQYISEKQRLSQASKAKRN
                     QAQQMAQASSKQKNKSIAPDRLSASKQKGTVEKAAQKQAKHIEKRMEHLEEVEKPQSYH
                     EFNFPQNKIYDIHNNYPIIAQNLTLVKGSQKLLTQVRFQIPYGKNIALVGANGVGKTTL
                     LEAIYHQIEGIDCSPKVQMAYYRQLAYEDMRDVSLLQYLMDETDSSESFSRAILNNLGL
                     NEALDRSCNVLSGGERTKLSLAVLFSTKANMLILDEPTNFLDIKTLEALEMFMNKYPGI
                     ILFTSHDTRFVKHVSDKKWELTGQSLHDIT"
                     /name="ABC-F type ribosomal protection protein Msr(A)"
     gene            14065..14964
                     /gene="mph(C)"
                     /locus_tag="DQV06_15390"
     ARG             14066..14961
                     /name="mph(C)"
                     /gene="mph(C)"
                     /gene_name="Mph(C) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            15450..16058
                     /locus_tag="DQV06_15395"
     CDS             15450..16058
                     /locus_tag="DQV06_15395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="QFK79027.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEIIETVNYLKEKDVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRV
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDKGLS"
                     /name="recombinase family protein"
     gene            16304..16642
                     /locus_tag="DQV06_15400"
     CDS             16304..16642
                     /locus_tag="DQV06_15400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QFK79028.1"
                     /translation="MNLIPFIIILIFSCLWTAITNKYLPSETLDKKGQQDRYDERQRKM
                     FIEILAKSFIWIVYCMLFTLVLKFTGLSPSIEGSWFSQYPEIFFIIVALFLMLFNYYTT
                     NKKYTSKG"
                     /name="hypothetical protein"
     gene            16647..16832
                     /locus_tag="DQV06_15405"
     CDS             16647..16832
                     /locus_tag="DQV06_15405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011276570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="QFK79029.1"
                     /translation="MKNRIREYRKQKGISQETLSKELKVSRQTINAIENNKYDPTLTLA
                     FKLARLFDTTVDELFS"
                     /name="transcriptional regulator"
     gene            complement(17059..17802)
                     /locus_tag="DQV06_15410"
     CDS             complement(17059..17802)
                     /locus_tag="DQV06_15410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002508633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="QFK79030.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     gene            18228..19211
                     /locus_tag="DQV06_15415"
     CDS             18228..19211
                     /locus_tag="DQV06_15415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="QFK79031.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNK
                     PNILYLMKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSKIERPEVRK
                     SNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNQFTHNFDDKEMLLQEFPE
                     QLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHD
                     RGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication protein"
     gene            19204..19520
                     /locus_tag="DQV06_15420"
                     /pseudo=""
     CDS             19204..19520
                     /locus_tag="DQV06_15420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002483623.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /name="replication protein"
     ARG             12501..13963
                     /name="msr(A)"
                     /gene="msr(A)"
                     /gene_name="ABC-F type ribosomal protection protein Msr(A)"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             6826..8579
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.38"
                     /coverage="100.0"
     ARG             complement(5877..6718)
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             2430..3043
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             12501..13966
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="98.36"
                     /coverage="100.0"
     ARG             14066..14964
                     /name="mphC"
                     /gene="mphC"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="98.66"
                     /coverage="100.0"
     ARG             complement(5874..6718)
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     Typing          19577..19724
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          complement(17060..17802)
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          18229..19211
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.593"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          19343..19512
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="93.605"
                     /coverage="91.0"
                     /evalue="1.04e-65"
ORIGIN
        1 tgaagattaa aactttcgct acttttactc atcgtcaatt agataaacaa gttaataggt
       61 ttttaaagaa tgatattcat gtattagaaa ttcaaacaca cagtaattgg ttatatattt
      121 cagctattgt tttttatgag gataaataag gaacatcgta tttatgccga aaaaatttat
      181 tgatgttgag aagaaccctt aactaaactt gcagacgaat gtcggcatag cgtgagctat
      241 taagccgacc attcgacaag ttttgggatt gttaagggtt ccgaggctca acgtcaataa
      301 aacaattgga ataaaatcaa cctacagagc atccagctgc aaatgcagtt ccgcaaactg
      361 cttcacatac accgccggct attggattta cgattgccca tactccacag tagtgagcac
      421 atgcataaag tccagccata ctacaagcga atgctttgcc gttccatttg aatcctgcat
      481 atgttaccgg tctgttttta tcaacttttt cagccttata ttcaacgtaa tttttgttaa
      541 taagtatttt tccctctttg ttttcagtca tacttctttt ttcggcaatg aattttgtga
      601 tttttttgtt gtagttatca tatattgttt cagaaactac aatttctttt gttttttcat
      661 ttttataagc gttattagct atgtagccat atgcattttt atcatttgct tctgtagcta
      721 gatattttaa tttagaattt ttgtcttcta gctttatttt tttaaatcct tcttttttca
      781 tttgcttttc gaatttttgc atatcttcat ttttattttg caattgttct agaaaactta
      841 tttctttctt ggtcatttgt gatacttcga tgtttttgct tttcaatttt tctttttgat
      901 tttctagtaa agaacttttt tgttcttcat ttgcgtaagc attagaaaaa ttcgcgctaa
      961 ataccagtag gaacaaggaa attattgaaa ataattttat aattttcatt tgatacctcc
     1021 aagataataa gatattttaa ttgtataagt aagcgcttta taaaatcaat atttatttta
     1081 atatatttat aaacatattt ttgaaaggag tctattttat gaatgaaaat ttagaaaaat
     1141 atataaaaag tttgccactt ttaggtttgt taattagtat tttgttaatt gttttattct
     1201 tttttatttt agatgttgat gaagatttat tcgtggtttt tttatactgt ttattgcctt
     1261 tgatagttaa tttgtctatt tatggttttt atgtttttgt taaaagaaag taagattatg
     1321 aataattttg tttttaattt gtatgctttg agggggttgg aaaacggtag gtgtatagat
     1381 tagatttctt gtttttttga aacgagtgtg aacgagtttc ttcttgtctt gatttttgat
     1441 aaaaacgccc tacaggaatt tagaaaaacg tggggaagtt ttaaagaatt ttatgctaat
     1501 ttttaatttg catgtaaatg ggcagtgtct aaaaatagtt attgtttttg ctcaaatttt
     1561 tgtttttgaa aatagcatat atttatttgg ctcatatttg cgttttaaaa gcatatataa
     1621 gttttagata taaaactata tgaatcaccc ctaaatcttt aaaatgccct cttaaaattc
     1681 aaaataaggg cataaaaaat aaaagctacc ccagataaag tgaggtagct ttttctttca
     1741 tacggtctat ttatttttct ttcgacgccg tatcgtcgat gtaattcaaa aaagttatgg
     1801 gctataaatc tacatcactt tttcaagaat gtagtagcaa tattcaacgc aaattaattt
     1861 ttataactgc tcggaatatc tcaagccgtt tctttaattt tgaaataaaa aaatcgacga
     1921 aggtcgatta cgtttttgca catgtcgatt tatccgacgt ataagtgcgc ccttacggga
     1981 tttaactaga ttataacgac gaattttaga cctgtaaagc aataacaatt aggtctacca
     2041 ggtagataaa gtgtacaaag tagaaccgaa aaagttattt attttgaaga tttttcgtag
     2101 atataatttg ctaataaact tcctaaaact gaataaagaa aaatagttaa actcatgtaa
     2161 tcactccata attctgaagt gtctccatgt ctacgcatag acacgcattt atgccgaaaa
     2221 aatttattga tgttgagaag aacccttaac taaacttgca gacgaatgtc ggcatagcgt
     2281 gagctattaa gccgaccatt cgacaagttt tgggattgtt aagggttccg aggctcaacg
     2341 tcaataaagc aattggaata aagcacctat gattatttaa aaatataagt tataatacat
     2401 tcaaaaatat ttttgaatga ggtgtattat gattcaaacg gttgttgctg ctgctgttct
     2461 ttatattgct acagcagttg atttattagt aattttatta atattttttg ctagagcaaa
     2521 gactagaaaa gaatatagag atatttatgt tggtcaatat ttagggtcta ttattttaat
     2581 attagttagt ttgtttttag cttttgtatt aaattatgtt ccagaaaagt ggatattagg
     2641 tttattgggt ttaataccaa tttatcttgg aattaaagtg gctatttatg atgattgtga
     2701 aggagaaaag agagctaaaa aagaattgaa tgaaaaagga ttgtctaaat tagttggtac
     2761 ggttgcaatt gttacgatag caagttgtgg cgccgataat attggtttat ttgttccgta
     2821 ttttgtgaca ttaagtgtta ctaatttatt acttactctg tttgtctttt taattttaat
     2881 tttcttcttg gtgtttactg cacaaaaatt agctaatatt ccaggaattg gagaaattgt
     2941 tgagaaattt agtcgttgga ttatggctat tatttatata gctttaggtt tatttattat
     3001 tattgaaaat gacactattc aaacaatttt aggatttata ttttaattta gggtgtgatt
     3061 ttatatgagt tatgaaaata cttgtgatgt gatctgtgta catgaggata aagttaacaa
     3121 tgctttaagt tttttagaag atgataaatc taagaaatta cttaacattt tagaaaaaat
     3181 ttgtgatgag aagaaattga aaatcatatt atctttgatt aaagaagatg agttgtgtgt
     3241 ttgtgatatt tctttgatat tgaaaatgag tgttgcttca acttcacatc atttaaggct
     3301 tttatataaa aatgaggtac ttgattttta taaagatgga aagatggcat attattttat
     3361 taaagacgat gaaataagag agtttttctc taaaaatcat gagggttttt gaaacgagtt
     3421 tcttcttgtc ttgatactat aaaaaacaaa gttatataac ataagacgac ttatcggaag
     3481 tagatatgct tgtatattca cagatggtat aataatagag tcgcctatct ctcaggcgtc
     3541 aattgacgaa gagaggaggt gcattacttt gctaatcatt ttcgttcaca tcatagcacc
     3601 agtcatcagt ggctgtgctg ttgcgtatta tacttattgg cttagtaaac gcaacaaata
     3661 attaataggc gactttataa gccagcatcg aaaaaatccc cacactactg caatagtgtg
     3721 gggattggtg cattaattgt taatcatttt cgttatataa attataacac tggttagtag
     3781 agaaatgcaa aatgattgaa ttaatagtaa atgtattaat gaatactcac acttatactt
     3841 ttaaaatagt tcttcctaaa tgttgtcctt ttaaaagctg atctatcgtt ttatagaatt
     3901 cttcaaatcc aatttcattg tatagaagtg aatttcctat attccattca tttgctaact
     3961 tactccatat atcttcacgg atattatgat caacatatac agaatcaatg ccaattaatt
     4021 taatacctct aagaataaac ggtaatatat tagcgttaag tgaatttcct gctacatttc
     4081 cacatacagt agcaacacct tgataattta gacgttttaa accgtataat gttacattac
     4141 tccccactgt atctaagaaa taatcaaaaa tacctttttt aagcggttta ttatcatctt
     4201 caattattat tacttgtttt gcacctaatt tttttgcgat ttctatttgc ttttcttttc
     4261 ttacgatagc agtgatattt tcatatccaa ttttatgtaa aatttgtata gcaacactgc
     4321 ccacaccacc tgtagcccca gacactaaaa tttcaggttg tgatttgata ttcattccat
     4381 atttttctag ttcaaaaatt gataatgctg ccgtaaaacc ggctgtgcca tataccatag
     4441 actctttaat agacatttct tggggaatag gaacaatcca ctctccaggc acttgtgcat
     4501 attctgaaaa tccacctgta tgtgtcacgc caacatcata accagtaact aatacattat
     4561 cgccttcttt aaacttatca ttcgaacttg attcaacaat acctgcaaaa tctataccag
     4621 gaatcatagg ataatctcta attacaccgc ctttatattg taaagctagc atatccttat
     4681 aatttattga agagtatacc acttttacta atacatcacc cttcgataaa tgagattcat
     4741 caactttttc tactttataa ctaacatttg atgcactttt tctcactact accgcattga
     4801 acatttatta gccttctttc acaattgttt tgtagaagta tgtttttgtt gcaaaactat
     4861 tttcctacaa aacttatcat gatatgataa gcgagtcaat actaatgatt taagagaggt
     4921 tttagttgtg gaattagata attgtataaa ttatttgttg agtacttctc agaatagagt
     4981 ttttaaacat tttaaaagtt tattaagtcc ctataatatt actccagcag aatatggtgt
     5041 tttgaattgc ttgattaata gtaatttgaa tacacctaaa gcgattggta atactttaaa
     5101 tttagaacct tcaacaatat ctggaatatt agataagatg tccaaaaagg atctaataac
     5161 acgtcaaact gataatgaaa atagaagaac tgtgctaata aacagtacaa ataaagcaaa
     5221 agacttatgg ccaacattag aaaagaaagc ctatcaactt aataatcatt acttcgctaa
     5281 tttaactaat gaagaaactg tagtgtttaa aaagatatta ctaaagataa ataaaactac
     5341 gttttaattt ttacgttata aaaaagttga agtgcgaatt ataatcgagt aaatataaat
     5401 gatagcttag cttaattata tattaaagcc aactatactt ttattcccga aaaacctact
     5461 atccaaattt ctaagatact ttagcctcta taataaacat attgtaatat aatttatgta
     5521 ttatttaggt ttaccctaat cgaacaataa aaaatacttg taaaatgcta ttgtcacttt
     5581 gcttgatata tgagaattat ttaaccttat aaatgagaaa aaagcaacgc actttaaata
     5641 agatacgttg ctttttcgat tgatgaacac ctataattaa actattcatc tattatttat
     5701 gattttttgt atatacaata tttctagttt gttaaagaga attaagaaaa taaatctcga
     5761 aaataataaa gggaaaatca gtttttgata tcaaaattat acatgtcaac gataatacaa
     5821 aatataatac aaactataag atgttatcag tatttattat gcatttagaa tattaaaatt
     5881 ccttcattac actcttggcg gtttcactta tcaacttatc atttggctta tcacttttat
     5941 tgtctttatt cgtaaaaatg actaaaacaa taggttcaga ttggccctta ggataaacaa
     6001 aagcaacatc atttctagaa gcatatgtta ttgcttgacc acttttatca gcaaccttat
     6061 agtcttttgg aacaccatct ttaattaaag tgtctccgtt tttattatta aacattaaat
     6121 caagtaagaa atttttattt tttttgctta attttccatt tgcgataagt ttatttaaag
     6181 tcttgccgaa agcagcaggc gttgaagtat cttttttgct ctttggtgaa tagtaattta
     6241 attctatctc atatctaact ggatttgtta ctttatctcc tagttctttt agacgttgtt
     6301 taactttttt gattccaccg atttctttta taattttatt gtttgctgta ttatcactat
     6361 atgtcattga agcctcaata agttctttta aagtgatatc ttttcctaca tatttttcta
     6421 aaataggaga ataagcaact atatcatctt tgttaatatg tactttttta tttaacttat
     6481 tataaggtac ttgttctaac aaaatagcac tatttatcgc ttttgaagtc gaagcatagg
     6541 caaatctctt atctgaatta aattttactt ccttaccact tttagtattt aaagcataaa
     6601 caccaatatg agcattatat tttttttcta aatcatttaa ctctttggca tgtgaactgt
     6661 ttgaattaca tgcacttaaa actaaagcaa ttacaattaa aaatattaac tttttcaaaa
     6721 taaaccctcc gatattacag ttgtaatttt tataaatcaa taatattaca attgtaatat
     6781 tgatgtcaat tgtttattat aaatatttga aagaaggtgt caaaatggct aaattactaa
     6841 taatgagcgt agtaagcttt tgttttatat ttctattgtt agtatttttt aggtacatat
     6901 taaaacgcta ttttaattat agtttaaatt ataaagtttg gtatctaact atgcttgctg
     6961 gattaattcc ttttatccca attaaattct cttttataaa atttaataat gtgaataatc
     7021 aagcgcccac agttgaaagt aagtcacacg atttgaacca taacataaat accaccaaac
     7081 ctattcaaga gttcacaaca gatatccata agtttaattg ggattcaatt gataatatct
     7141 gcacagttat ttggatagtt ttagttatta ttttaagttt taaatttttg aaagccttat
     7201 tatatcttaa atatttaaag aaacagtcac tttatctaaa cgaaaatgaa aaaaataaaa
     7261 tagatacgat acttttcaac catcaatata aaaaaaatat tgtgattcga aaagcagagg
     7321 ctattcaatc tccaataact ttttggtatg ggaaatatat tattttgatt cctagttcat
     7381 attttaaaag tgtaattgat aaaagactaa aatatataat actgcatgaa tatgctcatg
     7441 ctaaaaatag agatacttta catttaatta tctttaatat cttctctatt attatgagtt
     7501 acaatccatt agtacatatt gtaaaaagaa agataattca tgacaatgaa gtagaagccg
     7561 atagatttgt ccttaataat attaacaaaa atgaatttaa aacttatgcg gaatctatta
     7621 tggactccgt attaaaaacc ccattttcca acaaaaatat attaagccat tcatttaatg
     7681 gtaaaaaatc attactcaaa agtagattaa ttaatataaa agaagccgat ctgaaaaagc
     7741 agtcaaaatt aattctaatt tttatttgta tttttacttt ttttatcatg ataattcaaa
     7801 gccagttttt aatggggcaa tccttaactg attataatta taaaaagccc ttacaaagcg
     7861 attaccaaat tttagatgaa agtaaaaatt ttggttcaaa tagtggatct ttcgttatgt
     7921 acagcatgaa gaaagacaaa tactatattt ataatgaaaa agaaagtaga aaaagatatt
     7981 ctcctgattc aacttacaaa atttatttag cactgtttgg acttgaccgt catattataa
     8041 gtgataaaaa ttcacgtatg tcatggaatc ataaacatta tcttttcgag tcttggaata
     8101 aggaacaaga tttaaataca gcaatgcaaa attcagttaa ttggtacttc gaacgtatta
     8161 gtaatcaaat accaaagaac tatactgcgg ctcaactcaa gcaattaaat tatggtaatg
     8221 aaaatttggg aagttataaa agctattgga tggaagatag tttgaaaata tctaatcttg
     8281 aacaagtaat agtttttaaa aatatgatgg aacaaaataa ccattttagt aaaaaagcaa
     8341 agaatcaatt atcttcttca ttattgatta agaaaaatga aaagtatgaa ctgtatggga
     8401 aaacaggtac aggtatagta aacgggaagt ataataatgg gtggtttgta ggttacgtaa
     8461 ttacaaatca tgataagtat tattttgcta cacatttatc agatggaaac ccgtctggga
     8521 aaaatgctga attaataagt gaaaaaatat taaaaggaat gggtgtttta aatgaccaat
     8581 aagcaagttg aaatatctat ggctgaatgg gatgttatga atataatatg ggataaaaaa
     8641 tcagtatcag ctaatgaaat tgtagttgaa attcaaaaat ataaagaagt tagtgataaa
     8701 acgattagaa cattaatcac aagactatat aaaaaagaga ttataaaacg atacaaatca
     8761 gaaaatattt atttttactc atcaaatatt aaagaagacg atattaaaat gaaaactgct
     8821 aaaacctttc ttaataaact gtatggaggg gatatgaaaa gtttagtgct gaattttgcg
     8881 aaaaatgaag aattaaataa caaagaaatt gaagaattgc gagacatttt aaatgatatt
     8941 agtaaaaagt aattagaggt atgtttcaaa cataatacat atgtaaacca tacttgactc
     9001 ttattaaatt agttttgtta atgacattta aaatatatta ttaaagatga gagtgtccag
     9061 aaaataacca ttttctgtac actcttgttt tttgtctaaa taagtaagta ttacatagaa
     9121 ttatgtgttc aaaaacccaa caaaaaatct atgttcacaa aagacctcgt aatcaagtta
     9181 tggtacacta aaggtgtata taggaggtct gtattttgaa aataggttat gcaagagttt
     9241 caactggatt acaaaatttg aatttacagg aggatcgatt aaatacatat ggttgtgaaa
     9301 agatatttaa tgaccatatg agtggttcaa aaagtaagcg acctggttta gataaagcaa
     9361 ttgaatttgc gaggtcagga gatacgattg ttgtttggag attagataga ctaggacgga
     9421 acatggagga tttaatcacg ttagttaatg aacttaacga acgaggtgtg agttttcata
     9481 gtttagaaga aaatataacg atggataaat caagttctac aggacaatta ttatttcatt
     9541 tattcgcagc atttgcagag tttgaacgta atttaatttt agagcgatca tcagccggtc
     9601 gaattgcagc acgtgctaga ggccgatatg gaggtagacc tgaaaaatta aataaacaag
     9661 atttaaactt acttaagaca ctttatgata atggtacgcc aattaaaaca attgcagagc
     9721 agtggcaagt ttcacgtaca actatttatc gttatctcaa taaattagag gcaaaagaga
     9781 ataaaaacaa gtagagcaac taatctagct tactataatg aatctactaa ataattttat
     9841 atatcattaa catacaaaga ctttgattca atgtcactcg atgtaaaaga gacgttctga
     9901 cagcgtctaa aatctcataa tattttcctg ttatgagatt ttaataataa cacaagaaaa
     9961 aagcgtacaa attcgtacgc ttttttaata taatacctgt ttcactaatg aacgttttaa
    10021 gtatcttcat cattaactga aactacagta ataatactcg tcaacaatat tagtatagtt
    10081 aaaatagaaa gacttaggac tggcataacc gaactaaaat tatatttgaa atataaaagt
    10141 gctaatgaag agagaaatgt aaaaataata aataccaaag accatttttc taatttattc
    10201 attggcttca cctctttgaa cttttatata atcataggag atatttttac tacgatttat
    10261 aaaaaataag aagataatca ttattaaaga aacgattaat ataatgttga atcctatagt
    10321 atcacctaat tcgtttacac ctttgcctaa tatcggagat acaaagcttt gtattaataa
    10381 tgaaagagat gcccatatag taaatgaggt tctgttgcaa agttgaattt atagtataat
    10441 tttaacaaaa aggagtcttc tgtatgaact atttcagata taaacaattt aacaaggatg
    10501 ttatcactgt agctgttggc tactatctaa gatatgcatt gagttatcgt gatatatctg
    10561 aaatattaag ggaacgtggt gtaaacgttc atcattcaac ggtctaccgt tgggttcaag
    10621 aatatgcccc aattttatat caaatttgga agaaaaagca taaaaaagct tattacaaat
    10681 ggcgtattga tgagacgtac atcaaaataa aaggaaaatg gagctattta tatcgtgcca
    10741 ttgatgcaga gggacataca ttagatattt ggttgcgtaa gcaacgagat aatcattcag
    10801 catatgcgtt tatcaaacgt ctcattaaac aatttggtaa acctcaaaag gtaattacag
    10861 atcaggcacc ttcaacgaag gtagcaatgg ttaaagtaat taaagctttt aaacttaaac
    10921 ctgactgcca ttgtacatcg aaatatctga ataacctcat tgagcaagat caccgtcata
    10981 ttaaagtaag aaagacaagg tatcaaagta tcaatacagc aaagaatact ttaaaaggta
    11041 ttgagtgtat ttacgctcta tataaaaaga accgcaggtc tcttcagatc tacggatttt
    11101 cgccatgcca cgaaattagc atcatgctag caagttaagc gaacactgac atgataaatt
    11161 agtggttagc tatatttttt actttgcaac agaaccagca tttgttttaa tatttgttcc
    11221 aaagagccat catggctttg acagagctct tcttctatgc aaatgctttt aatccgatcc
    11281 acacgaaaat tccggttctg ttgcaaagta aaaaatatag ctaatcacta atatatcatg
    11341 tcagtgttcg tttaacttgc tagcatgatg ctaatttcgt ggcatgggga aaatccgtag
    11401 atctgaagag acctacggtt ctttttatat agagcgtaaa tacattcaat accttttaaa
    11461 gtattctttg ccgtattgat actttgatat cttgtctttc ttactttaat atgacggtga
    11521 tcttgctcaa tgaggttatt cagatatttc gatgtacaat gacagtcagg tttaagttta
    11581 aaagctttaa ttattttagc cattgctgcc ttcgttgaag gtgcctgatc tgtaactacc
    11641 ttttgaggct taccaaattg tttaatgaga cgtttgataa acgcatatgc tgaatgatta
    11701 tctcgttgct tacgcaacca aatatctaat gtatgtccct ctgtatcaat ggcacgatat
    11761 aaatagctcc attttccttt tattttgata tacgtctcat caatacgcca tttgtaataa
    11821 gcttttttat gctttttctt ccaaatttga tataaaattg gggcatattc ttgaacccaa
    11881 cggtagatcg ttgaatgatg aacgtttaca ccacgttctc ttaatatttc agatatatca
    11941 cgatagctca atgcatatct tagatagtag ccaacggcta cagtgataac atccttgtta
    12001 aattgtttat atctgaaata gttcatacag aagactcctt tttgttaaaa ttatattata
    12061 aattcaactt tgcaacagaa ccgtatttta tgagtacact ctaaattaag gagatgtata
    12121 atcaatctaa aattgtattt ttatactttt gttatataat ctttctactt agagatatat
    12181 tgtaaaaaaa ccaacaaaat gttatattaa cattactatt ttatcgatga aggaggatta
    12241 aaatgacagc ttctatgaga ctcaaataaa cctttttgaa tacaaaacta aattaattca
    12301 aaaaggcttg tccgcaatac acactcatag gatgacttat gtcatttttt atccttcgat
    12361 aggaataata aacgctttca aatactaaaa catcataata aatttttaag tgtttgaaag
    12421 tgtaatgtga atgagacggg agtagcctgt ctcatttttt tgcgtacacg tcctttaaat
    12481 atacaaggag tgtataaata tggaacaata tacaattaaa tttaaccaaa tcaatcataa
    12541 attgacagat ttacgatcac ttaacatcgg tcatctttac gcttaccaat ttgaaaaaat
    12601 agcacttatt gggggtaatg gtactggcaa aaccacatta ctaaatatga ttgctcaaaa
    12661 aacaaaacca gaatctggaa cagttgaaac ggttggcgaa attcaatatt ttgaacagct
    12721 taacatggat gtggaaaatg attttaacac gttagacggt agtttaatga gtgaactcca
    12781 tatacctatg catacaaccg acagtatgag tggtggtgaa aaagcaaaat ataaattagc
    12841 taatgtcata tcaaattata gtccgatatt acttttagat gaacctacaa atcacttgga
    12901 taaaattggt aaagattatc tgaaaaatat tttaaaatat tactatggta ctttaattat
    12961 agtaagtcat gatagagcac ttatagacca aattgctgac acaatttggg atatacaaga
    13021 agatggcaca ataagagtgt ttaaaggtaa ttacacacag tatcaaaatc aatatgaaca
    13081 agaacagtta gaacaacaac gtcaatatga acagtatata agtgaaaaac aaagattgtc
    13141 ccaagccagt aaagctaaac gaaatcaagc gcaacaaatg gcacaagcat catcaaaaca
    13201 aaaaaacaaa agtatagcac cagatcgttt aagtgcatca aaacaaaaag gcacggttga
    13261 gaaggctgct caaaaacaag ctaagcatat tgaaaaaaga atggaacatt tggaagaagt
    13321 tgaaaaacca caaagttatc atgaattcaa tttcccacaa aataaaattt atgatatcca
    13381 taataattat ccaatcattg cacaaaatct aacattggtt aaaggaagtc aaaaactgct
    13441 aacacaagta cgattccaaa taccatatgg caaaaatata gcgctcgtag gtgcaaatgg
    13501 tgtaggtaag acaactttac ttgaagctat ttaccaccaa atagagggaa ttgattgttc
    13561 tcctaaagtg caaatggcat actatcgtca acttgcttat gaagacatgc gtgacgtttc
    13621 attattgcaa tatttaatgg atgaaacgga ttcatcagaa tcattcagta gagctatttt
    13681 aaataacttg ggtttaaatg aagcacttga tcgttcttgt aatgttttga gtggtgggga
    13741 aagaacgaaa ttatcgttag cagtattatt ttcaacgaaa gcgaatatgt taattttgga
    13801 tgaaccaact aattttttag atattaaaac attagaagca ttagaaatgt ttatgaataa
    13861 atatcctgga atcattttgt ttacatcaca tgatacaagg tttgttaaac atgtatcaga
    13921 taaaaaatgg gaattaacag gacaatctct tcatgatata acttaaaaac tatacactaa
    13981 tttatattga atattaggtt catttatatc aatataaaaa atacgttcac aagaaaaata
    14041 taatagaaat aaggatccaa taaaatgact cgacataatg aaattattaa atgtgcagaa
    14101 aaatatcaat tacacatcca acctcaaaca atctcattga atgaatcggg acttgatttt
    14161 caagttgcat ttggaaaaga taaacatgga gtagaatggg ttttgagact accaagaaga
    14221 cctgacgttt ataaacgaac aaaacccgaa aaacaaacgg tagacttctt acagaagaat
    14281 gtttcatttg aaataccgaa gtggaaagta catgcaaaag accttattgc ttacccaaaa
    14341 cttacaggta aacccgcagc cacaatagat ccagaaatac aaaattatgt atgggaaatt
    14401 gaacacaaac cattaccaga aaactttatt aacacattag ctgaaacact cgtagattta
    14461 cacaacatac cagaagaaaa cattaacgtt cagcatataa atatcaaaac catacaagaa
    14521 ataaaaaatg actttcaaag aagaatgaat aaagttaaag aaacttatgg cgtatcagat
    14581 gaattatgga acagatggaa acaatggtta gaaaacgacg aactatggcc tcgacatgcg
    14641 accatgatac atggggactt acatccagga catataatgg tagataacca agcaaacgtc
    14701 acaggtctca tagactggac tgaagcaacc cactccgacc catcaatgga ctttatagga
    14761 caccatcgtg tattcgacga cgaaggatta gagcaactta taacagcata cggtaaagct
    14821 ggaggtgaaa tatggccacg aatgaaagag catataatag aactcaatgc agtattccca
    14881 atgtttatcg ctgagtttgc tatggaatca ggagaatcgg cgtatgaaac gatggcattg
    14941 aaagagttag gtatgaaaga gtagaactta tattaaaaga ggcccatttt aaagacgaag
    15001 gcaatcctga tgaaatttta aaactgcgtt taattagtga tggtctttgg ttttctataa
    15061 tgtattaaat atctggacat ggaacaaatg caacaaatgg aaagaatcgt tttcgaaatt
    15121 tctaactcct taaatcagga ggataaataa acggtcattt tcattgaaag cacttatata
    15181 aatttcatca attttaatac ctaccgtaaa tacatttcat aagtattaaa cagatgatta
    15241 aaatttttag ttaatttaaa tatttatgat agagatgacc ttcaaatgaa cggttctgtt
    15301 acaaagaaaa aatctatatt tatttttagt aagttttaat tatagatatg tacactttga
    15361 gtacacccta accatacaaa aagaattgtt gaaattataa caattaaaac gtatgattag
    15421 ggtgtatatt tattatggag tgaagatgaa tgattatagg ttatgcgaga gtatcatcga
    15481 tagatcaaaa tttagaaaga caattggata atttaaagac gtttggtgtg gagaaaatct
    15541 ttacagagaa acagtcggga aagtcagtgg aaaatagacc tgtatttcaa gaagcactca
    15601 attttgtcag aatgggagat cgattcgttg tggaatctat tgatcgttta ggacgtaact
    15661 atgatgaaat tattgaaact gtgaattatt taaaagaaaa agacgttcag ttaatgatta
    15721 ccagcttacc tatgatgaat gaagtaattg gcaatccatt actggataag tttatgaaag
    15781 atttaatcat tcaaatatta gcaatggttt cagaacaaga gagaaatgaa agtaaacgtc
    15841 gacaagcgca agggattcaa gttgcgaagg aaaaaggcgt atataaaggg cgccctttac
    15901 tttattcacc aaatgctaaa gacccacaga aacgtgttat ttatcatcgc gtggtggaaa
    15961 tgttagaaga aggcaaagcg attagtaaga ttgcgaaaga agttaatatc acaagacaaa
    16021 cagtttatag aattaaacat gataagggat tatcttgata aattgattgt caatgcaaat
    16081 gagcgtctct cacagtgtct caaattccat aacatattat tgaattgaga ttttaataat
    16141 tatacaagaa aaaagagtac gagttcgcag ctttctatat agtaattgtt ttactaataa
    16201 ggtgttttaa aatatattat aatgtaaaaa gtatttgaca tttgtatcaa aaatatttac
    16261 actcataaat gtcaaatact ttttacattt atgaggtgtt ataatgaatt taattccttt
    16321 tattattatt ttaatttttt cttgtttatg gacggctata actaacaaat atttaccttc
    16381 agaaacatta gataaaaaag gacaacaaga tcgatacgat gaaagacaac gtaaaatgtt
    16441 tattgaaata ctggctaaaa gttttatttg gattgtatat tgtatgttat ttacactagt
    16501 gcttaaattt acaggtttgt caccaagtat tgaaggatct tggttttctc aatatccaga
    16561 aattttcttt ataattgtag cactatttct tatgctgttt aattactata ctacaaataa
    16621 aaaatataca tctaaaggtt aaattaatga aaaatagaat tagagaatat agaaaacaaa
    16681 aaggaatttc tcaagaaact ttaagtaaag aattaaaagt gtctaggcaa actattaatg
    16741 caatagaaaa caataaatat gatcctacat tgacattagc atttaagttg gcaagattgt
    16801 ttgatacaac tgtggatgaa ttattttctt aaccattcat ttatcacaaa aagagagtgc
    16861 gaattcgcac tctctttttg tgtagtagta ctattaaatt ttgtctcaat aacgaacgtt
    16921 tataacgcaa tcatgatgag agtattaata cagttaatta tttgaaatac tttagtttac
    16981 ataatcgatg attaccagaa gttctcacta tataaaagac actaaaattt tataactttt
    17041 agtgcctaat caattatttt agctaccaaa caaacgactc caaaacccct ttttaggttc
    17101 cgtttcttca ctcttttctt ctatatcact atcattgtca tttagattag ctggaacgtc
    17161 ttcttttttt gcttcttcac cttgtgtact ttcgtcgctt tgacttccag atatatcctt
    17221 atattgaatc tctgtttctt tagtttcttc ctgatctctg ttaatattta caggattagt
    17281 agtatatgtt ttttcttgtg catcaacgtt ttgtctagtg ttagtagatg tatcaaaggg
    17341 ataattaagg tgtttttctt tttctaattg attttctaat ttttgaatct ttttattact
    17401 ctctaatgcc agaacttgct gattttcaag caattttgat ctttcttgca actcttttct
    17461 gtaaaattca attgttgttt catgacgact ttcttgtttt tcaatttgat tatttaaagt
    17521 atcaatctga tttttaagga tttctactat ttgagcatcg cttttcgatt caaaattaat
    17581 attatccgac cctttttttt gtttgtcttc agtagtactt tcaaaaccat atttcttttt
    17641 attttcattt actctttgaa tgattttttc tatatcggta tcttctttaa taaacgaagt
    17701 gttttcctgt tttattgtct ctatattcaa tcgcttaata ttattaaaaa tcgtttgctt
    17761 actaacccct aattcttcac tcaacttttt cacacttttc atatcatcaa ccctttataa
    17821 aatgtttata aacccttgat aaaatattat aagcttataa tgcttaataa taaagtgatt
    17881 aataaataaa aataaacatc catcaacctt tttatcaagg gtttatgaaa ggtttatgat
    17941 atttatcaag ggtttataaa cccttgataa agctatattt tcccttttat aagtttattt
    18001 aaagtgctat aataaactta atataacaaa aaccccaact actggtaata gtcggggttt
    18061 ggtaataaaa cgtttagaaa ctgtttattt atataatttt cgatacttgt attatataat
    18121 gaataatatc ttagtgcaag cacctaaatc attaaataaa tgtaaagcta aataaaaacg
    18181 ttttattacc tcttaccaaa ctaaaatatg gaaagaggtt ttttgtcatg caaaatcaat
    18241 attttacagt gcaagaaaat tacaaagaaa gattttatca aatccctaaa gtattcttta
    18301 ccagtgaaaa ttataaaaat ctaactaatg atatgaaaat agcctatgct atcttacgtg
    18361 atcgcttaaa tttatctatt aaaaatagct gggttgatga agatggtaac atttactttg
    18421 tttattcaaa tgaaaagcta atggaaatct taaattgtaa aaaagaaaag ttaacaaaaa
    18481 taaaaaaagg gttagaaaac gatggtctac tcattcaaaa acgacgtggt ttaaataaac
    18541 caaatattct atatttaatg aaacctattg tcacagaacg tgatatttac aaaatagaaa
    18601 aagaagaaaa cgatgttgaa ccttacggcg agaaggaagt tcgaaaatcg aacgtccaga
    18661 agttcgaaaa tcgaacgtcc agaagttcga aaatcgaacg tccagaagtt cgaaaatcga
    18721 acactaatga tactgacttt aatgacattg actttaatga tactgagaat aatgatatga
    18781 atgacttgaa tgatataaag tacaaaaatg aaattagtaa tcattcaaat cattcaaatc
    18841 aatttacaca taattttgat gataaagaaa tgctattgca agaattccca gaacaactaa
    18901 ctaattattt attaaaatat gattatagag atttagaaat cataaaggct gttattctta
    18961 aagcaaaaaa atcatttaat tcaaggcatg aagatatgca ttacatgtta gaggacattg
    19021 aggatgaaat attaacttct ttaaaaagac ttaaaaaagc tatacatgat aggggagtta
    19081 aaggccaaaa ggaaacaatc aagtcaatgc aagcttattt aatgcaaaca attctaactg
    19141 aacttgaaga aacacatgcc ctttatatgc gccgtaaaaa catgaaacaa tataatatct
    19201 ttaatcaata attcaaatga ttttataaca ctcgaagaga catcaaaata ttccgttaaa
    19261 tcatctgact ttttaactga tgacgacgaa aaaaatcaag aaattgtaag tgatttagaa
    19321 aaaggtttgt atcgaaaacg tatgttaagt tatggtggat tgcttaaaca aaagcataaa
    19381 attttaaact tagacgatgc cgaagatggt aatttgatta atacaagtga tgaagataaa
    19441 acgacagacg aagaaaaaaa gcacattcaa ttaccgcaat ttggaatttc gaaaagcaaa
    19501 attattattt aagacattag tgataactga tgtctttttt tattgttttt ctgtaaaaaa
    19561 gtgctgtctt atttttgtga caaatgctgt atgtagtgtc acaaaagtgt gacactacag
    19621 ctttgtatga tatcacttta aaataactta aaacccttgg aatgtctggc cttgccagat
    19681 ctatcatttt tgaatgatag caaatttccc ttatgctctt acggagattt tagagttaaa
    19741 ttaaaatttc taagtttttg ataagaaaag ccctgcagga atttagaaaa acatggggaa
    19801 gttttaaagt attttatgct aatttttaaa tttgcatgta aatgggcagt atctaaaaaa
    19861 ttagtcactg attttgctga aatttttgtt tgtgaaatta gcatatattt atttggctca
    19921 tatttgcgtt ttaagagact gtatagattt ttaagtacaa aacctatatg atttgcctct
    19981 aagtcttcaa aatgcctctt aaaatccaaa ataaaagtgt ttaatattgt aataaggatt
    20041 gctattttta taaaaggaga gatatca
//
