LOCUS       CP030436               19523 bp    DNA     circular BCT 10-OCT-2019
DEFINITION  Staphylococcus aureus strain ER04086.3 plasmid unnamed1, complete
            sequence.
ACCESSION   CP030436
VERSION     CP030436.1
DBLINK      BioProject: PRJNA470993
            BioSample: SAMN09484042
KEYWORDS    .
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
            Staphylococcus.
REFERENCE   1  (bases 1 to 19523)
  AUTHORS   Sullivan,M.J., Altman,D.R., Chacko,K., Cliferri,B., Webster,E.,
            Deikus,G., Lewis,M., Khan,Z., Beckford,C., Rendo,A., Samaroo,F.,
            Sebra,R., Karam-Howlin,R., Southwick,K., Adams,E., Ying,L.,
            Kornblum,J., Factor,S., Danesh Yazdi,M., Dingle,T., Hamula,C.,
            Bashir,A., Schadt,E., Kasarskis,A., Patel,G., Wallach,F., Gibbs,K.
            and van Bakel,H.
  TITLE     Whole genome sequencing to identify and define MRSA outbreaks
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 19523)
  AUTHORS   Sullivan,M.J., Altman,D.R., Chacko,K., Cliferri,B., Webster,E.,
            Deikus,G., Lewis,M., Khan,Z., Beckford,C., Rendo,A., Samaroo,F.,
            Sebra,R., Karam-Howlin,R., Southwick,K., Adams,E., Ying,L.,
            Kornblum,J., Factor,S., Danesh Yazdi,M., Dingle,T., Hamula,C.,
            Bashir,A., Schadt,E., Kasarskis,A., Patel,G., Wallach,F., Gibbs,K.
            and van Bakel,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUN-2018) Genetics and Genomic Sciences, Icahn School
            of Medicine, One Gustave L. Levy Place Box 1498, New York, NY 10029,
            USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.2.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 270.26594514x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI
            Annotation Date                   :: 06/29/2018 20:11:27
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            Annotation Method :: Best-placed reference protein set; GeneMarkS+
            Annotation Software revision      :: 4.5
            Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; repeat_region
            Genes (total)                     :: 3,046
            CDS (total)                       :: 2,964
            Genes (coding)                    :: 2,882
            CDS (coding)                      :: 2,882
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 43 of 82
            Pseudo Genes (incomplete)         :: 36 of 82
            Pseudo Genes (internal stop)      :: 23 of 82
            Pseudo Genes (multiple problems)  :: 19 of 82
            ##Genome-Annotation-Data-END##
            Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..19523
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /strain="ER04086.3"
                     /isolation_source="nares"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /plasmid="unnamed1"
                     /geo_loc_name="USA:New York City"
                     /lat_lon="40.7903114 N 73.9528738 W"
                     /collection_date="2015"
                     /collected_by="Mount Sinai Hospital"
     gene            join(18554..19523,1..2)
                     /locus_tag="DQV61_00005"
     CDS             join(18554..19523,1..2)
                     /locus_tag="DQV61_00005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH:quinone reductase"
                     /protein_id="QFJ56461.1"
                     /translation="MFNAVVVRKSASNVSYKVEKVDESHLSKGDVLVKVVYSSINYKDM
                     LALQYKGGVIRDYPMIPGIDFAGIVESSSNDKFKEGDNVLVTGYDVGVTHTGGFSEYAQ
                     VPGEWIVPIPQEMSIKESMVYGTAGFTAALSIFELEKYGMNIKSQPEILVSGATGGVGS
                     VAIQILHKIGYENITAIVRKEKQIEIAKKLGAKQVIIIEDDNKPLKKGIFDYFLDTVGS
                     NVTLYGLKRLNYQGVATVCGNVAGNSLNANILPFILRGIKLIGIDSVYVDHNIREDIWS
                     KLANEWNIGNSLLYNEIGFEEFYKTIDQLLKGQHLGRTILKV"
                     /name="NADPH:quinone reductase"
     gene            complement(174..266)
                     /locus_tag="DQV61_00010"
     CDS             complement(174..266)
                     /locus_tag="DQV61_00010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002495832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="QFJ56444.1"
                     /translation="MLIIFVHIIAPVISGCAVAYYTYWLSKRNK"
                     /name="type I toxin-antitoxin system Fst family toxin"
     gene            complement(423..770)
                     /locus_tag="DQV61_00015"
     CDS             complement(423..770)
                     /locus_tag="DQV61_00015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020366422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="QFJ56445.1"
                     /translation="MSYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
                     /name="transcriptional regulator"
     gene            complement(789..1406)
                     /locus_tag="DQV61_00020"
     CDS             complement(789..1406)
                     /locus_tag="DQV61_00020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017465246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium transporter"
                     /protein_id="QFJ56446.1"
                     /translation="MIQTVVAAAVLYIATAVDLLVILLIFFARAKTRKEYRDIYVGQYL
                     GSIILILVSLFLAFVLNYVPEKWILGLLGLIPIYLGIKVAIYDDCEGEKRAKKELNEKG
                     LSKLVGTVAIVTIASCGADNIGLFVPYFVTLSVTNLLLTLFVFLILIFFLVFTAQKLAN
                     IPGIGEIVEKFSRWIMAIIYIALGLFIIIENDTIQTILGFIF"
                     /name="cadmium transporter"
     gene            complement(2522..2716)
                     /locus_tag="DQV61_00025"
     CDS             complement(2522..2716)
                     /locus_tag="DQV61_00025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001004925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QFJ56447.1"
                     /translation="MNENLEKYIKSLPLLGLLISILLIVLFFFILDVDEDLFVVFLYCL
                     LPLIVNLSIYGFYVFVKRK"
                     /name="hypothetical protein"
     gene            2826..3518
                     /locus_tag="DQV61_00030"
     CDS             2826..3518
                     /locus_tag="DQV61_00030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QFJ56448.1"
                     /translation="MKIIKLFSIISLFLLVFSANFSNAYANEEQKSSLLENQKEKLKSK
                     NIEVSQMTKKEISFLEQLQNKNEDMQKFEKQMKKEGFKKIKLEDKNSKLKYLATEANDK
                     NAYGYIANNAYKNEKTKEIVVSETIYDNYNKKITKFIAEKRSMTENKEGKILINKNYVE
                     YKAEKVDKNRPVTYAGFKWNGKAFACSMAGLYACAHYCGVWAIVNPIAGGVCEAVCGTA
                     FAAGCSVG"
                     /name="hypothetical protein"
     gene            complement(4382..4698)
                     /locus_tag="DQV61_00035"
                     /pseudo=""
     CDS             complement(4382..4698)
                     /locus_tag="DQV61_00035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002483623.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /name="replication protein"
     gene            complement(4691..5674)
                     /locus_tag="DQV61_00040"
     CDS             complement(4691..5674)
                     /locus_tag="DQV61_00040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="QFJ56449.1"
                     /translation="MQNQYFTVQENYKERFYQIPKVFFTSENYKNLTNDMKIAYAILRD
                     RLNLSIKNSWVDEDGNIYFVYSNEKLMEILNCKKEKLTKIKKGLENDGLLIQKRRGLNK
                     PNILYLMKPIVTERDIYKIEKEENDVEPYGEKEVRKSNVQKFENRTSRSSKIERPEVRK
                     SNTNDTDFNDIDFNDTENNDMNDLNDIKYKNEISNHSNHSNQFTHNFDDKEMLLQEFPE
                     QLTNYLLKYDYRDLEIIKAVILKAKKSFNSRHEDMHYMLEDIEDEILTSLKRLKKAIHD
                     RGVKGQKETIKSMQAYLMQTILTELEETHALYMRRKNMKQYNIFNQ"
                     /name="replication protein"
     gene            6100..6843
                     /locus_tag="DQV61_00045"
     CDS             6100..6843
                     /locus_tag="DQV61_00045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002508633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="QFJ56450.1"
                     /translation="MKSVKKLSEELGVSKQTIFNNIKRLNIETIKQENTSFIKEDTDIE
                     KIIQRVNENKKKYGFESTTEDKQKKGSDNINFESKSDAQIVEILKNQIDTLNNQIEKQE
                     SRHETTIEFYRKELQERSKLLENQQVLALESNKKIQKLENQLEKEKHLNYPFDTSTNTR
                     QNVDAQEKTYTTNPVNINRDQEETKETEIQYKDISGSQSDESTQGEEAKKEDVPANLND
                     NDSDIEEKSEETEPKKGFWSRLFGS"
                     /name="DUF536 domain-containing protein"
     gene            complement(7070..7255)
                     /locus_tag="DQV61_00050"
     CDS             complement(7070..7255)
                     /locus_tag="DQV61_00050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011276570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="QFJ56451.1"
                     /translation="MKNRIREYRKQKGISQETLSKELKVSRQTINAIENNKYDPTLTLA
                     FKLARLFDTTVDELFS"
                     /name="transcriptional regulator"
     gene            complement(7260..7598)
                     /locus_tag="DQV61_00055"
     CDS             complement(7260..7598)
                     /locus_tag="DQV61_00055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="QFJ56452.1"
                     /translation="MNLIPFIIILIFSCLWTAITNKYLPSETLDKKGQQDRYDERQRKM
                     FIEILAKSFIWIVYCMLFTLVLKFTGLSPSIEGSWFSQYPEIFFIIVALFLMLFNYYTT
                     NKKYTSKG"
                     /name="hypothetical protein"
     gene            complement(7844..8452)
                     /locus_tag="DQV61_00060"
     CDS             complement(7844..8452)
                     /locus_tag="DQV61_00060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002474535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="QFJ56453.1"
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEIIETVNYLKEKDVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRV
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKHDKGLS"
                     /name="recombinase family protein"
     gene            complement(8938..9837)
                     /gene="mph(C)"
                     /locus_tag="DQV61_00065"
     ARG             complement(8942..9837)
                     /name="mph(C)"
                     /gene="mph(C)"
                     /gene_name="Mph(C) family macrolide 2'-phosphotransferase"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE"
                     /identity="100.0"
                     /coverage="100.0"
     gene            complement(9908..11396)
                     /locus_tag="DQV61_00070"
                     /pseudo=""
     CDS             complement(9908..11396)
                     /locus_tag="DQV61_00070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002447408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide efflux ABC transporter Msr(A)"
                     /name="macrolide efflux ABC transporter Msr(A)"
     gene            11870..12160
                     /locus_tag="DQV61_00075"
                     /pseudo=""
     CDS             11870..12160
                     /locus_tag="DQV61_00075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015311.1"
                     /note="incomplete; partial on complete genome; missing
                     stop; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /name="IS6 family transposase"
     gene            complement(12220..12894)
                     /locus_tag="DQV61_00080"
     CDS             complement(12220..12894)
                     /locus_tag="DQV61_00080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="QFJ56455.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMVKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
                     /name="IS6-like element IS257 family transposase"
     gene            complement(13564..14142)
                     /locus_tag="DQV61_00085"
     CDS             complement(13564..14142)
                     /locus_tag="DQV61_00085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="QFJ56456.1"
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTYGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWQVSRTTIYRYLNKLEAKENKNK"
                     /name="HTH domain-containing protein"
     gene            complement(14406..14786)
                     /gene="blaI"
                     /locus_tag="DQV61_00090"
     ARG             complement(14410..14786)
                     /name="blaI"
                     /gene="blaI"
                     /gene_name="penicillinase repressor BlaI"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="98.41"
                     /coverage="100.0"
     gene            complement(14776..16533)
                     /locus_tag="DQV61_00095"
     CDS             complement(14776..16533)
                     /locus_tag="DQV61_00095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactam sensor/signal transducer BlaR1"
                     /protein_id="QFJ56458.1"
                     /translation="MAKLLIMSVVSFCFIFLLLVFFRYILKRYFNYSLNYKVWYLTMLA
                     GLIPFIPIKFSFIKFNNVNNQAPTVESKSHDLNHNINTTKPIQEFTTDIHKFNWDSIDN
                     ICTVIWIVLVIILSFKFLKALLYLKYLKKQSLYLNENEKNKIDTILFNHQYKKNIVIRK
                     AEAIQSPITFWYGKYIILIPSSYFKSVIDKRLKYIILHEYAHAKNRDTLHLIIFNIFSI
                     IMSYNPLVHIVKRKIIHDNEVEADRFVLNNINKNEFKTYAESIMDSVLKTPFSNKNILS
                     HSFNGKKSLLKSRLINIKEADLKKQSKLILIFICIFTFFIMIIQSQFLMGQSLTDYNYK
                     KPLQSDYQILDESKNFGSNSGSFVMYSMKKDKYYIYNEKESRKRYSPDSTYKIYLALFG
                     LDRHIISDKNSRMSWNHKHYLFESWNKEQDLNTAMQNSVNWYFERISNQIPKNYTAAQL
                     KQLNYGNENLGSYKSYWMEDSLKISNLEQVIVFKNMMEQNNHFSKKAKNQLSSSLLIKK
                     NEKYELYGKTGTGIVNGKYNNGWFVGYVITNHDKYYFATHLSDGNPSGKNAELISEKIL
                     KGMGVLNDQ"
                     /name="beta-lactam sensor/signal transducer BlaR1"
     gene            16640..17485
                     /locus_tag="DQV61_00100"
     CDS             16640..17485
                     /locus_tag="DQV61_00100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /protein_id="QFJ56459.1"
                     /translation="MKKLIFLIVIALVLSACNSNSSHAKELNDLEKKYNAHIGVYALNT
                     KSGKEVKFNSDKRFAYASTSKAINSAILLEQVPYNKLNKKVHINKDDIVAYSPILEKYV
                     GKDITLKELIEASMTYSDNTANNKIIKEIGGIKKVKQRLKELGDKVTNPVRYEIELNYY
                     SPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKNFLLDLMFNNKNGDTLIKDGVPKDYKV
                     ADKSGQAITYASRNDVAFVYPKGQSEPIVLVIFTNKDNKSDKPNDKLISETAKSVMKEF
                     "
                     /name="penicillin-hydrolyzing class A beta-lactamase BlaZ"
     gene            17694..17789
                     /locus_tag="DQV61_00105"
                     /pseudo=""
     CDS             17694..17789
                     /locus_tag="DQV61_00105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001560862.1"
                     /note="incomplete; partial on complete genome; missing
                     stop; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /pseudo=""
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase domain-containing protein"
                     /name="O-antigen ligase domain-containing protein"
     gene            complement(18011..18430)
                     /locus_tag="DQV61_00110"
     CDS             complement(18011..18430)
                     /locus_tag="DQV61_00110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="QFJ56460.1"
                     /translation="MELDNCINYLLSTSQNRVFKHFKSLLSPYNITPAEYGVLNCLINS
                     NLNTPKAIGNTLNLEPSTISGILDKMSKKDLITRQTDNENRRTVLINSTNKAKDLWPTL
                     EKKAYQLNNHYFANLTNEETVVFKKILLKINKTTF"
                     /name="MarR family transcriptional regulator"
     ARG             complement(9973..11396)
                     /name="msr(A)"
                     /gene="msr(A)"
                     /gene_name="ABC-F type ribosomal protection protein Msr(A)"
                     /tool="amrfinderplus"
                     /drug_class="MACROLIDE/STREPTOGRAMIN"
                     /identity="100.0"
                     /coverage="97.34"
     ARG             complement(14780..16533)
                     /name="blaR1"
                     /gene="blaR1"
                     /gene_name="beta-lactam sensor/signal transducer BlaR1"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="95.38"
                     /coverage="100.0"
     ARG             16641..17482
                     /name="blaZ"
                     /gene="blaZ"
                     /gene_name="penicillin-hydrolyzing class A beta-lactamase
                     BlaZ"
                     /tool="amrfinderplus"
                     /drug_class="BETA-LACTAM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(793..1406)
                     /name="cadD"
                     /gene="cadD"
                     /gene_name="cadmium resistance transporter CadD"
                     /tool="amrfinderplus"
                     /drug_class="CADMIUM"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(9943..11396)
                     /name="msrA"
                     /gene="msrA"
                     /gene_name="msr-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; streptogramin
                     antibiotic; streptogramin B antibiotic"
                     /identity="98.53"
                     /coverage="99.18"
     ARG             complement(8939..9837)
                     /name="mphC"
                     /gene="mphC"
                     /gene_name="macrolide phosphotransferase (MPH)"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic"
                     /identity="98.66"
                     /coverage="100.0"
     ARG             16641..17485
                     /name="PC1 beta-lactamase (blaZ)"
                     /gene="PC1 beta-lactamase (blaZ)"
                     /gene_name="BlaZ beta-lactamase"
                     /tool="rgi"
                     /drug_class="penam"
                     /identity="96.8"
                     /coverage="100.0"
     Typing          complement(4179..4326)
                     /name="MOBQ"
                     /typing="oriT"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="5.980000000000001e-72"
     Typing          complement(4385..4560)
                     /name="rep_cluster_1017"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="92.697"
                     /coverage="94.0"
                     /evalue="1.04e-65"
     Typing          complement(4692..5674)
                     /name="rep_cluster_2100"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.593"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          6101..6843
                     /name="rep_cluster_1733"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="100.0"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 aagtgtgagt attcattaat acatttacta ttaattcaat cattttgcat ttctctacta
       61 accagtgtta taatttatat aacgaaaatg attaacaatt aatgcaccaa tccccacact
      121 attgcagtag tgtggggatt ttttcgatgc tggcttataa agtcgcctat taattatttg
      181 ttgcgtttac taagccaata agtataatac gcaacagcac agccactgat gactggtgct
      241 atgatgtgaa cgaaaatgat tagcaaagta atgcacctcc tctcttcgtc aattgacgcc
      301 tgagagatag gcgactctat tattatacca tctgtgaata tacaagcata tctacttccg
      361 ataagtcgtc ttatgttata taactttgtt ttttatagta tcaagacaag aagaaactcg
      421 tttcaaaaac cctcatgatt tttagagaaa aactctctta tttcatcgtc tttaataaaa
      481 taatatgcca tctttccatc tttataaaaa tcaagtacct catttttata taaaagcctt
      541 aaatgatgtg aagttgaagc aacactcatt ttcaatatca aagaaatatc acaaacacac
      601 aactcatctt ctttaatcaa agataatatg attttcaatt tcttctcatc acaaattttt
      661 tctaaaatgt taagtaattt cttagattta tcatcttcta aaaaacttaa agcattgtta
      721 actttatcct catgtacaca gatcacatca caagtatttt cataactcat ataaaatcac
      781 accctaaatt aaaatataaa tcctaaaatt gtttgaatag tgtcattttc aataataata
      841 aataaaccta aagctatata aataatagcc ataatccaac gactaaattt ctcaacaatt
      901 tctccaattc ctggaatatt agctaatttt tgtgcagtaa acaccaagaa gaaaattaaa
      961 attaaaaaga caaacagagt aagtaataaa ttagtaacac ttaatgtcac aaaatacgga
     1021 acaaataaac caatattatc ggcgccacaa cttgctatcg taacaattgc aaccgtacca
     1081 actaatttag acaatccttt ttcattcaat tcttttttag ctctcttttc tccttcacaa
     1141 tcatcataaa tagccacttt aattccaaga taaattggta ttaaacccaa taaacctaat
     1201 atccactttt ctggaacata atttaataca aaagctaaaa acaaactaac taatattaaa
     1261 ataatagacc ctaaatattg accaacataa atatctctat attcttttct agtctttgct
     1321 ctagcaaaaa atattaataa aattactaat aaatcaactg ctgtagcaat ataaagaaca
     1381 gcagcagcaa caaccgtttg aatcataata cacctcattc aaaaatattt ttgaatgtat
     1441 tataacttat atttttaaat aatcataggt gctttattcc aattgcttta ttgacgttga
     1501 gcctcggaac ccttaacaat ccgaaaactt gtcgaatggt cggcttaata gctcacgcta
     1561 tgccgacatt cgtctgcaag tttagttaag ggttcttctc aacatcaata aattttttcg
     1621 gcataaatgc gtgtctatgc gtagacatgg agacacttca gaattatgga gtgattacat
     1681 gagtttaact atttttcttt attcagtttt aggaagttta ttagcaaatt atatctacga
     1741 aaaatcttca aaataaataa ctttttcggt tctactttgt acactttatc tacctggtag
     1801 acctaattgt tattgcttta caggtctaaa attcgtcgtt ataatctagt taaatcccgt
     1861 aagggcgcac ttatacgtcg gataaatcga catgtgcaaa aacgtaatcg accttcgtcg
     1921 atttttttat ttcaaaatta aagaaacggc ttgagatatt ccgagcagtt ataaaaatta
     1981 atttgcgttg aatattgcta ctacattctt gaaaaagtga tgtagattta tagcccataa
     2041 cttttttgaa ttacatcgac gatacggcgt cgaaagaaaa ataaatagac cgtatgaaag
     2101 aaaaagctac ctcactttat ctggggtagc ttttattttt tatgccctta ttttgaattt
     2161 taagagggca ttttaaagat ttaggggtga ttcatatagt tttatatcta aaacttatat
     2221 atgcttttaa aacgcaaata tgagccaaat aaatatatgc tattttcaaa aacaaaaatt
     2281 tgagcaaaaa caataactat ttttagacac tgcccattta catgcaaatt aaaaattagc
     2341 ataaaattct ttaaaacttc cccacgtttt tctaaattcc tgtagggcgt ttttatcaaa
     2401 aatcaagaca agaagaaact cgttcacact cgtttcaaaa aaacaagaaa tctaatctat
     2461 acacctaccg ttttccaacc ccctcaaagc atacaaatta aaaacaaaat tattcataat
     2521 cttactttct tttaacaaaa acataaaaac cataaataga caaattaact atcaaaggca
     2581 ataaacagta taaaaaaacc acgaataaat cttcatcaac atctaaaata aaaaagaata
     2641 aaacaattaa caaaatacta attaacaaac ctaaaagtgg caaacttttt atatattttt
     2701 ctaaattttc attcataaaa tagactcctt tcaaaaatat gtttataaat atattaaaat
     2761 aaatattgat tttataaagc gcttacttat acaattaaaa tatcttatta tcttggaggt
     2821 atcaaatgaa aattataaaa ttattttcaa taatttcctt gttcctactg gtatttagcg
     2881 cgaatttttc taatgcttac gcaaatgaag aacaaaaaag ttctttacta gaaaatcaaa
     2941 aagaaaaatt gaaaagcaaa aacatcgaag tatcacaaat gaccaagaaa gaaataagtt
     3001 ttctagaaca attgcaaaat aaaaatgaag atatgcaaaa attcgaaaag caaatgaaaa
     3061 aagaaggatt taaaaaaata aagctagaag acaaaaattc taaattaaaa tatctagcta
     3121 cagaagcaaa tgataaaaat gcatatggct acatagctaa taacgcttat aaaaatgaaa
     3181 aaacaaaaga aattgtagtt tctgaaacaa tatatgataa ctacaacaaa aaaatcacaa
     3241 aattcattgc cgaaaaaaga agtatgactg aaaacaaaga gggaaaaata cttattaaca
     3301 aaaattacgt tgaatataag gctgaaaaag ttgataaaaa cagaccggta acatatgcag
     3361 gattcaaatg gaacggcaaa gcattcgctt gtagtatggc tggactttat gcatgtgctc
     3421 actactgtgg agtatgggca atcgtaaatc caatagccgg cggtgtatgt gaagcagttt
     3481 gcggaactgc atttgcagct ggatgctctg taggttgatt ttattccaat tgttttattg
     3541 acgttgagcc tcggaaccct taacaatccc aaaacttgtc gaatggtcgg cttaatagct
     3601 cacgctatgc cgacattcgt ctgcaagttt agttaagggt tcttctcaac atcaataaat
     3661 tttttcggca taaatacgat gttccttatt tatcctcata aaaaacaata gctgaaatat
     3721 ataaccaatt actgtgtgtt tgaatttcta atacatgaat atcattcttt aaaaacctat
     3781 taacttgttt atctaattga cgatgagtaa aagtagcgaa agttttaatc ttcatgatat
     3841 ctctcctttt ataaaaatag caatccttat tacaatatta aacactttta ttttggattt
     3901 taagaggcat tttgaagact tagaggcaaa tcatataggt tttgtactta aaaatctata
     3961 cagtctctta aaacgcaaat atgagccaaa taaatatatg ctaatttcac aaacaaaaat
     4021 ttcagcaaaa tcagtgacta attttttaga tactgcccat ttacatgcaa atttaaaaat
     4081 tagcataaaa tactttaaaa cttccccatg tttttctaaa ttcctgcagg gcttttctta
     4141 tcaaaaactt agaaatttta atttaactct aaaatctccg taagagcata agggaaattt
     4201 gctatcattc aaaaatgata gatctggcaa ggccagacat tccaagggtt ttaagttatt
     4261 ttaaagtgat atcatacaaa gctgtagtgt cacacttttg tgacactaca tacagcattt
     4321 gtcacaaaaa taagacagca cttttttaca gaaaaacaat aaaaaaagac atcagttatc
     4381 actaatgtct taaataataa ttttgctttt cgaaattcca aattgcggta attgaatgtg
     4441 ctttttttct tcgtctgtcg ttttatcttc atcacttgta ttaatcaaat taccatcttc
     4501 ggcatcgtct aagtttaaaa ttttatgctt ttgtttaagc aatccaccat aacttaacat
     4561 acgttttcga tacaaacctt tttctaaatc acttacaatt tcttgatttt tttcgtcgtc
     4621 atcagttaaa aagtcagatg atttaacgga atattttgat gtctcttcga gtgttataaa
     4681 atcatttgaa ttattgatta aagatattat attgtttcat gtttttacgg cgcatataaa
     4741 gggcatgtgt ttcttcaagt tcagttagaa ttgtttgcat taaataagct tgcattgact
     4801 tgattgtttc cttttggcct ttaactcccc tatcatgtat agctttttta agtcttttta
     4861 aagaagttaa tatttcatcc tcaatgtcct ctaacatgta atgcatatct tcatgccttg
     4921 aattaaatga tttttttgct ttaagaataa cagcctttat gatttctaaa tctctataat
     4981 catattttaa taaataatta gttagttgtt ctgggaattc ttgcaatagc atttctttat
     5041 catcaaaatt atgtgtaaat tgatttgaat gatttgaatg attactaatt tcatttttgt
     5101 actttatatc attcaagtca ttcatatcat tattctcagt atcattaaag tcaatgtcat
     5161 taaagtcagt atcattagtg ttcgattttc gaacttctgg acgttcgatt ttcgaacttc
     5221 tggacgttcg attttcgaac ttctggacgt tcgattttcg aacttccttc tcgccgtaag
     5281 gttcaacatc gttttcttct ttttctattt tgtaaatatc acgttctgtg acaataggtt
     5341 tcattaaata tagaatattt ggtttattta aaccacgtcg tttttgaatg agtagaccat
     5401 cgttttctaa cccttttttt atttttgtta acttttcttt tttacaattt aagatttcca
     5461 ttagcttttc atttgaataa acaaagtaaa tgttaccatc ttcatcaacc cagctatttt
     5521 taatagataa atttaagcga tcacgtaaga tagcataggc tattttcata tcattagtta
     5581 gatttttata attttcactg gtaaagaata ctttagggat ttgataaaat ctttctttgt
     5641 aattttcttg cactgtaaaa tattgatttt gcatgacaaa aaacctcttt ccatatttta
     5701 gtttggtaag aggtaataaa acgtttttat ttagctttac atttatttaa tgatttaggt
     5761 gcttgcacta agatattatt cattatataa tacaagtatc gaaaattata taaataaaca
     5821 gtttctaaac gttttattac caaaccccga ctattaccag tagttggggt ttttgttata
     5881 ttaagtttat tatagcactt taaataaact tataaaaggg aaaatatagc tttatcaagg
     5941 gtttataaac ccttgataaa tatcataaac ctttcataaa cccttgataa aaaggttgat
     6001 ggatgtttat ttttatttat taatcacttt attattaagc attataagct tataatattt
     6061 tatcaagggt ttataaacat tttataaagg gttgatgata tgaaaagtgt gaaaaagttg
     6121 agtgaagaat taggggttag taagcaaacg atttttaata atattaagcg attgaatata
     6181 gagacaataa aacaggaaaa cacttcgttt attaaagaag ataccgatat agaaaaaatc
     6241 attcaaagag taaatgaaaa taaaaagaaa tatggttttg aaagtactac tgaagacaaa
     6301 caaaaaaaag ggtcggataa tattaatttt gaatcgaaaa gcgatgctca aatagtagaa
     6361 atccttaaaa atcagattga tactttaaat aatcaaattg aaaaacaaga aagtcgtcat
     6421 gaaacaacaa ttgaatttta cagaaaagag ttgcaagaaa gatcaaaatt gcttgaaaat
     6481 cagcaagttc tggcattaga gagtaataaa aagattcaaa aattagaaaa tcaattagaa
     6541 aaagaaaaac accttaatta tccctttgat acatctacta acactagaca aaacgttgat
     6601 gcacaagaaa aaacatatac tactaatcct gtaaatatta acagagatca ggaagaaact
     6661 aaagaaacag agattcaata taaggatata tctggaagtc aaagcgacga aagtacacaa
     6721 ggtgaagaag caaaaaaaga agacgttcca gctaatctaa atgacaatga tagtgatata
     6781 gaagaaaaga gtgaagaaac ggaacctaaa aaggggtttt ggagtcgttt gtttggtagc
     6841 taaaataatt gattaggcac taaaagttat aaaattttag tgtcttttat atagtgagaa
     6901 cttctggtaa tcatcgatta tgtaaactaa agtatttcaa ataattaact gtattaatac
     6961 tctcatcatg attgcgttat aaacgttcgt tattgagaca aaatttaata gtactactac
     7021 acaaaaagag agtgcgaatt cgcactctct ttttgtgata aatgaatggt taagaaaata
     7081 attcatccac agttgtatca aacaatcttg ccaacttaaa tgctaatgtc aatgtaggat
     7141 catatttatt gttttctatt gcattaatag tttgcctaga cacttttaat tctttactta
     7201 aagtttcttg agaaattcct ttttgttttc tatattctct aattctattt ttcattaatt
     7261 taacctttag atgtatattt tttatttgta gtatagtaat taaacagcat aagaaatagt
     7321 gctacaatta taaagaaaat ttctggatat tgagaaaacc aagatccttc aatacttggt
     7381 gacaaacctg taaatttaag cactagtgta aataacatac aatatacaat ccaaataaaa
     7441 cttttagcca gtatttcaat aaacatttta cgttgtcttt catcgtatcg atcttgttgt
     7501 ccttttttat ctaatgtttc tgaaggtaaa tatttgttag ttatagccgt ccataaacaa
     7561 gaaaaaatta aaataataat aaaaggaatt aaattcatta taacacctca taaatgtaaa
     7621 aagtatttga catttatgag tgtaaatatt tttgatacaa atgtcaaata ctttttacat
     7681 tataatatat tttaaaacac cttattagta aaacaattac tatatagaaa gctgcgaact
     7741 cgtactcttt tttcttgtat aattattaaa atctcaattc aataatatgt tatggaattt
     7801 gagacactgt gagagacgct catttgcatt gacaatcaat ttatcaagat aatcccttat
     7861 catgtttaat tctataaact gtttgtcttg tgatattaac ttctttcgca atcttactaa
     7921 tcgctttgcc ttcttctaac atttccacca cgcgatgata aataacacgt ttctgtgggt
     7981 ctttagcatt tggtgaataa agtaaagggc gccctttata tacgcctttt tccttcgcaa
     8041 cttgaatccc ttgcgcttgt cgacgtttac tttcatttct ctcttgttct gaaaccattg
     8101 ctaatatttg aatgattaaa tctttcataa acttatccag taatggattg ccaattactt
     8161 cattcatcat aggtaagctg gtaatcatta actgaacgtc tttttctttt aaataattca
     8221 cagtttcaat aatttcatca tagttacgtc ctaaacgatc aatagattcc acaacgaatc
     8281 gatctcccat tctgacaaaa ttgagtgctt cttgaaatac aggtctattt tccactgact
     8341 ttcccgactg tttctctgta aagattttct ccacaccaaa cgtctttaaa ttatccaatt
     8401 gtctttctaa attttgatct atcgatgata ctctcgcata acctataatc attcatcttc
     8461 actccataat aaatatacac cctaatcata cgttttaatt gttataattt caacaattct
     8521 ttttgtatgg ttagggtgta ctcaaagtgt acatatctat aattaaaact tactaaaaat
     8581 aaatatagat tttttctttg taacagaacc gttcatttga aggtcatctc tatcataaat
     8641 atttaaatta actaaaaatt ttaatcatct gtttaatact tatgaaatgt atttacggta
     8701 ggtattaaaa ttgatgaaat ttatataagt gctttcaatg aaaatgaccg tttatttatc
     8761 ctcctgattt aaggagttag aaatttcgaa aacgattctt tccatttgtt gcatttgttc
     8821 catgtccaga tatttaatac attatagaaa accaaagacc atcactaatt aaacgcagtt
     8881 ttaaaatttc atcaggattg ccttcgtctt taaaatgggc ctcttttaat ataagttcta
     8941 ctctttcata cctaactctt tcaatgccat cgtttcatac gccgattctc ctgattccat
     9001 agcaaactca gcgataaaca ttgggaatac tgcattgagt tctattatat gctctttcat
     9061 tcgtggccat atttcacctc cagctttacc gtatgctgtt ataagttgct ctaatccttc
     9121 gtcgtcgaat acacgatggt gtcctataaa gtccattgat gggtcggagt gggttgcttc
     9181 agtccagtct atgagacctg tgacgtttgc ttggttatct accattatat gtcctggatg
     9241 taagtcccca tgtatcatgg tcgcatgtcg aggccatagt tcgtcgtttt ctaaccattg
     9301 tttccatctg ttccataatt catctgatac gccataagtt tctttaactt tattcattct
     9361 tctttgaaag tcatttttta tttcttgtat ggttttgata tttatatgct gaacgttaat
     9421 gttttcttct ggtatgttgt gtaaatctac gagtgtttca gctaatgtgt taataaagtt
     9481 ttctggtaat ggtttgtgtt caatttccca tacataattt tgtatttctg gatctattgt
     9541 ggctgcgggt ttacctgtaa gttttgggta agcaataagg tcttttgcat gtactttcca
     9601 cttcggtatt tcaaatgaaa cattcttctg taagaagtct accgtttgtt tttcgggttt
     9661 tgttcgttta taaacgtcag gtcttcttgg tagtctcaaa acccattcta ctccatgttt
     9721 atcttttcca aatgcaactt gaaaatcaag tcccgattca ttcaatgaga ttgtttgagg
     9781 ttggatgtgt aattgatatt tttctgcaca tttaataatt tcattatgtc gagtcatttt
     9841 attggatcct tatttctatt atatttttct tgtgaacgta ttttttatat tgatataaat
     9901 aataatatta atataatatt atgatatcta taagtttatt atcatgaaga gattgtcctg
     9961 ttaattccat ttttatctga tacatgttta acaaaccttg tatcatgtga tgtaaacaaa
    10021 atgattccag gatatttatt cataaacatt tctaatgctt ctaatgtttt aatatctaaa
    10081 aaattagttg gttcatccaa aattaacata ttcgctttcg ttgaaaataa tactgctaac
    10141 gataatttcg ttctttcccc accactcaaa acattacaag aacgatcaag tgcttcattt
    10201 aaacccaagt tatttaaaat agctctactg aatgattctg atgaatccgt ttcatccatt
    10261 aaatattgca ataatgaaac gtcacgcatg tcttcataag caagttgacg atagtatgcc
    10321 atttgcactt taggagaaca atcaattccc tctatttggt ggtaaatagc ttcaagtaaa
    10381 gttgtcttac ctacaccatt tgcacctacg agcgctatat ttttgccata tggtatttgg
    10441 aatcgtactt gtgttagcag tttttgactt cctttaacca atgttagatt ttgtgcaatg
    10501 attggataat tattatggat atcataaatt ttattttgtg ggaaattgaa ttcatgataa
    10561 ctttgtggtt tttcaacttc ttccaaatgt tccattcttt tttcaatatg cttagcttgt
    10621 ttttgagcag ccttctcaac cgtgcctttt tgttttgatg cacttaaacg atctggtgct
    10681 atacttttgt ttttttgttt tgatgatgct tgtgccattt gttgcgcttg atttcgttta
    10741 gctttactgg cttgggacaa tctttgtttt tcacttatat actgttcata ttgacgttgt
    10801 tgttctaact gttcttgttc atattgattt tgatactgtg tgtaattacc tttaaacact
    10861 cttattgtgc catcttcttg tatatcccaa attgtgtcag caatttggtc tataagtgct
    10921 ctatcatgac ttactataat taaagtacca tagtaatatt ttaaaatatt tttcagataa
    10981 tctttaccaa ttttatccaa gtgatttgta ggttcatcta aaagtaatat cggactataa
    11041 tttgatatga cattagctaa tttatatttt gctttttcac caccactcat actgtcggtt
    11101 gtatgcatag gtatatggag ttcactcatt aaactaccgt ctaacgtgtt aaaatcattt
    11161 tccacatcca tgttaagctg ttcaaaatat tgaatttcgc caaccgtttc aactgttcca
    11221 gattctggtt ttgttttttg agcaatcata tttagtaatg tggttttgcc agtaccatta
    11281 cccccaataa gtgctatttt ttcaaattgg taagcgtaaa gatgaccgat gttaagtgat
    11341 cgtaaatctg tcaatttatg attgatttgg ttaaatttaa ttgtatattg ttccatattt
    11401 atacactcct tgtatattta aaggacgtgt acgcaaaaaa atgagacagg ctactcccgt
    11461 ctcattcaca ttacactttc aaacacttaa aaatttatta tgatgtttta gtatttgaaa
    11521 gcgtttatta ttcctatcga aggataaaaa atgacataag tcatcctatg agtgtgtatt
    11581 gcggacaagc ctttttgaat taatttagtt ttgtattcaa aaaggtttat ttgagtctca
    11641 tagaagctgt cattttaatc ctccttcatc gataaaatag taatgttaat ataacatttt
    11701 gttggttttt ttacaatata tctctaagta gaaagattat ataacaaaag tataaaaata
    11761 caattttaga ttgattatac atctccttaa tttagagtgt actcataaaa tacggttctg
    11821 ttgcaaagtt gaatttataa tataatttta acaaaaagga gtcttctgta tgaactattt
    11881 cagatataaa caatttaaca aggatgttat cactgtagcc gttggctact atctaagata
    11941 tgcattgagc tatcgtgata tatctgaaat attaagagaa cgtggtgtaa acgttcatca
    12001 ttcaacgatc taccgttggg ttcaagaata tgccccaatt ttatatcaaa tttggaagaa
    12061 aaagcataaa aaagcttatt acaaatggcg tattgatgag acgtatatca aaataaaagg
    12121 aaaatggagc tatttatatc gtgccattga tacagaggga ggttctgttg caaagtaaaa
    12181 aaatatagct aaccactaat ttatcatgtc agtgttcgct taacttgcta gcatgatgct
    12241 aatttcgtgg catggcgaaa atccgtagat ctgaagagac ctgcggttct ttttatatag
    12301 agcgtaaata cactcaatac cttttaaagt attctttgct gtattgatac tttgatacct
    12361 tgtctttctt actttaatat gacggtgatc ttgctcaatg aggttattca gatatttcga
    12421 tgtacaatgg cagtcaggtt taagtttaaa agctttaatt actttaacca ttgctacctt
    12481 cgttgaaggt gcctgatctg taattacctt ttgaggttta ccaaattgtt taatgagacg
    12541 tttgataaac gcatatgctg aatgattatc tcgttgctta cgcaaccaaa tatctaatgt
    12601 atgtccctct gcatcaatgg cacgatataa atagctccat tttcctttta ttttgatgta
    12661 cgtctcatca atacgccatt tgtaataagc ttttttatgc tttttcttcc aaatttgata
    12721 taaaattggg gcatattctt gaacccaacg gtagaccgtt gaatgatgaa cgtttacacc
    12781 acgttccctt aatatttcag atatatcacg ataactcaat gcatatctta gatagtagcc
    12841 aacagctaca gtgataacat ccttgttaaa ttgtttatat ctgaaatagt tcatacagaa
    12901 gactcctttt tgttaaaatt atactataaa ttcaactttg caacagaacc tcatttacta
    12961 tatgggcatc tctttcatta ttaatacaaa gctttgtatc tccgatatta ggcaaaggtg
    13021 taaacgaatt aggtgatact ataggattca acattatatt aatcgtttct ttaataatga
    13081 ttatcttctt attttttata aatcgtagta aaaatatctc ctatgattat ataaaagttc
    13141 aaagaggtga agccaatgaa taaattagaa aaatggtctt tggtatttat tatttttaca
    13201 tttctctctt cattagcact tttatatttc aaatataatt ttagttcggt tatgccagtc
    13261 ctaagtcttt ctattttaac tatactaata ttgttgacga gtattattac tgtagtttca
    13321 gttaatgatg aagatactta aaacgttcat tagtgaaaca ggtattatat taaaaaagcg
    13381 tacgaatttg tacgcttttt tcttgtgtta ttattaaaat ctcataacag gaaaatatta
    13441 tgagatttta gacgctgtca gaacgtctct tttacatcga gtgacattga atcaaagtct
    13501 ttgtatgtta atgatatata aaattattta gtagattcat tatagtaagc tagattagtt
    13561 gctctacttg tttttattct cttttgcctc taatttattg agataacgat aaatagttgt
    13621 acgtgaaact tgccactgct ctgcaattgt tttaattggc gtaccattat cataaagtgt
    13681 cttaagtaag tttaaatctt gtttatttaa tttttcaggt ctacctccat atcggcctct
    13741 agcacgtgct gcaattcgac cggctgatga tcgctctaaa attaaattac gttcaaactc
    13801 tgcaaatgct gcgaataaat gaaataataa ttgtcctgta gaacttgatt tatccatcgt
    13861 tatattttct tctaaactat gaaaactcac acctcgttcg ttaagttcat taactaacgt
    13921 gattaaatcc tccatgttcc gtcctagtct atctaatctc caaacaacaa tcgtatctcc
    13981 tgacctcgca aattcaattg ctttatctaa accaggtcgc ttactttttg aaccactcat
    14041 atggtcatta aatatctttt cacaaccata tgtatttaat cgatcctcct gtaaattcaa
    14101 attttgtaat ccagttgaaa ctcttgcata acctattttc aaaatacaga cctcctatat
    14161 acacctttag tgtaccataa cttgattacg aggtcttttg tgaacataga ttttttgttg
    14221 ggtttttgaa cacataattc tatgtaatac ttacttattt agacaaaaaa caagagtgta
    14281 cagaaaatgg ttattttctg gacactctca tctttaataa tatattttaa atgtcattaa
    14341 caaaactaat ttaataagag tcaagtatgg tttacatatg tattatgttt gaaacatacc
    14401 tctaattact ttttactaat atcatttaaa atgtctcgca attcttcaat ttctttgtta
    14461 tttaattctt catttttcgc aaaattcagc actaaacttt tcatatcccc tccatacagt
    14521 ttattaagaa aggttttagc agttttcatt ttaatatcgt cttctttaat atttgatgag
    14581 taaaaataaa tattttctga tttgtatcgt tttataatct cttttttata tagtcttgtg
    14641 attaatgttc taatcgtttt atcactaact tctttatatt tttgaatttc aactacaatt
    14701 tcattagctg atactgattt tttatcccat attatattca taacatccca ttcagccata
    14761 gatatttcaa cttgcttatt ggtcatttaa aacacccatt ccttttaata ttttttcact
    14821 tattaattca gcatttttcc cagacgggtt tccatctgat aaatgtgtag caaaataata
    14881 cttatcatga tttgtaatta cgtaacctac aaaccaccca ttattatact tcccgtttac
    14941 tatacctgta cctgttttcc catacagttc atacttttca tttttcttaa tcaataatga
    15001 agaagataat tgattctttg cttttttact aaaatggtta ttttgttcca tcatattttt
    15061 aaaaactatt acttgttcaa gattagatat tttcaaacta tcttccatcc aatagctttt
    15121 ataacttccc aaattttcat taccataatt taattgcttg agttgagccg cagtatagtt
    15181 ctttggtatt tgattactaa tacgttcgaa gtaccaatta actgaatttt gcattgctgt
    15241 atttaaatct tgttccttat tccaagactc gaaaagataa tgtttatgat tccatgacat
    15301 acgtgaattt ttatcactta taatatgacg gtcaagtcca aacagtgcta aataaatttt
    15361 gtaagttgaa tcaggagaat atctttttct actttctttt tcattataaa tatagtattt
    15421 gtctttcttc atgctgtaca taacgaaaga tccactattt gaaccaaaat ttttactttc
    15481 atctaaaatt tggtaatcgc tttgtaaggg ctttttataa ttataatcag ttaaggattg
    15541 ccccattaaa aactggcttt gaattatcat gataaaaaaa gtaaaaatac aaataaaaat
    15601 tagaattaat tttgactgct ttttcagatc ggcttctttt atattaatta atctactttt
    15661 gagtaatgat tttttaccat taaatgaatg gcttaatata tttttgttgg aaaatggggt
    15721 ttttaatacg gagtccataa tagattccgc ataagtttta aattcatttt tgttaatatt
    15781 attaaggaca aatctatcgg cttctacttc attgtcatga attatctttc tttttacaat
    15841 atgtactaat ggattgtaac tcataataat agagaagata ttaaagataa ttaaatgtaa
    15901 agtatctcta tttttagcat gagcatattc atgcagtatt atatatttta gtcttttatc
    15961 aattacactt ttaaaatatg aactaggaat caaaataata tatttcccat accaaaaagt
    16021 tattggagat tgaatagcct ctgcttttcg aatcacaata ttttttttat attgatggtt
    16081 gaaaagtatc gtatctattt tatttttttc attttcgttt agataaagtg actgtttctt
    16141 taaatattta agatataata aggctttcaa aaatttaaaa cttaaaataa taactaaaac
    16201 tatccaaata actgtgcaga tattatcaat tgaatcccaa ttaaacttat ggatatctgt
    16261 tgtgaactct tgaataggtt tggtggtatt tatgttatgg ttcaaatcgt gtgacttact
    16321 ttcaactgtg ggcgcttgat tattcacatt attaaatttt ataaaagaga atttaattgg
    16381 gataaaagga attaatccag caagcatagt tagataccaa actttataat ttaaactata
    16441 attaaaatag cgttttaata tgtacctaaa aaatactaac aatagaaata taaaacaaaa
    16501 gcttactacg ctcattatta gtaatttagc cattttgaca ccttctttca aatatttata
    16561 ataaacaatt gacatcaata ttacaattgt aatattattg atttataaaa attacaactg
    16621 taatatcgga gggtttattt tgaaaaagtt aatattttta attgtaattg ctttagtttt
    16681 aagtgcatgt aattcaaaca gttcacatgc caaagagtta aatgatttag aaaaaaaata
    16741 taatgctcat attggtgttt atgctttaaa tactaaaagt ggtaaggaag taaaatttaa
    16801 ttcagataag agatttgcct atgcttcgac ttcaaaagcg ataaatagtg ctattttgtt
    16861 agaacaagta ccttataata agttaaataa aaaagtacat attaacaaag atgatatagt
    16921 tgcttattct cctattttag aaaaatatgt aggaaaagat atcactttaa aagaacttat
    16981 tgaggcttca atgacatata gtgataatac agcaaacaat aaaattataa aagaaatcgg
    17041 tggaatcaaa aaagttaaac aacgtctaaa agaactagga gataaagtaa caaatccagt
    17101 tagatatgag atagaattaa attactattc accaaagagc aaaaaagata cttcaacgcc
    17161 tgctgctttc ggcaagactt taaataaact tatcgcaaat ggaaaattaa gcaaaaaaaa
    17221 taaaaatttc ttacttgatt taatgtttaa taataaaaac ggagacactt taattaaaga
    17281 tggtgttcca aaagactata aggttgctga taaaagtggt caagcaataa catatgcttc
    17341 tagaaatgat gttgcttttg tttatcctaa gggccaatct gaacctattg ttttagtcat
    17401 ttttacgaat aaagacaata aaagtgataa gccaaatgat aagttgataa gtgaaaccgc
    17461 caagagtgta atgaaggaat tttaatattc taaatgcata ataaatactg ataacatctt
    17521 atagtttgta ttatattttg tattatcgtt gacatgtata attttgatat caaaaactga
    17581 ttttcccttt attattttcg agatttattt tcttaattct ctttaacaaa ctagaaatat
    17641 tgtatataca aaaaatcata aataatagat gaatagttta attataggtg ttcatcaatc
    17701 gaaaaagcaa cgtatcttat ttaaagtgcg ttgctttttt ctcatttata aggttaaata
    17761 attctcatat atcaagcaaa gtgacaatag cattttacaa gtatttttta ttgttcgatt
    17821 agggtaaacc taaataatac ataaattata ttacaatatg tttattatag aggctaaagt
    17881 atcttagaaa tttggatagt aggtttttcg ggaataaaag tatagttggc tttaatatat
    17941 aattaagcta agctatcatt tatatttact cgattataat tcgcacttca acttttttat
    18001 aacgtaaaaa ttaaaacgta gttttattta tctttagtaa tatcttttta aacactacag
    18061 tttcttcatt agttaaatta gcgaagtaat gattattaag ttgataggct ttcttttcta
    18121 atgttggcca taagtctttt gctttatttg tactgtttat tagcacagtt cttctatttt
    18181 cattatcagt ttgacgtgtt attagatcct ttttggacat cttatctaat attccagata
    18241 ttgttgaagg ttctaaattt aaagtattac caatcgcttt aggtgtattc aaattactat
    18301 taatcaagca attcaaaaca ccatattctg ctggagtaat attataggga cttaataaac
    18361 ttttaaaatg tttaaaaact ctattctgag aagtactcaa caaataattt atacaattat
    18421 ctaattccac aactaaaacc tctcttaaat cattagtatt gactcgctta tcatatcatg
    18481 ataagttttg taggaaaata gttttgcaac aaaaacatac ttctacaaaa caattgtgaa
    18541 agaaggctaa taaatgttca atgcggtagt agtgagaaaa agtgcatcaa atgttagtta
    18601 taaagtagaa aaagttgatg aatctcattt atcgaagggt gatgtattag taaaagtggt
    18661 atactcttca ataaattata aggatatgct agctttacaa tataaaggcg gtgtaattag
    18721 agattatcct atgattcctg gtatagattt tgcaggtatt gttgaatcaa gttcgaatga
    18781 taagtttaaa gaaggcgata atgtattagt tactggttat gatgttggcg tgacacatac
    18841 aggtggattt tcagaatatg cacaagtgcc tggagagtgg attgttccta ttccccaaga
    18901 aatgtctatt aaagagtcta tggtatatgg cacagccggt tttacggcag cattatcaat
    18961 ttttgaacta gaaaaatatg gaatgaatat caaatcacaa cctgaaattt tagtgtctgg
    19021 ggctacaggt ggtgtgggca gtgttgctat acaaatttta cataaaattg gatatgaaaa
    19081 tatcactgct atcgtaagaa aagaaaagca aatagaaatc gcaaaaaaat taggtgcaaa
    19141 acaagtaata ataattgaag atgataataa accgcttaaa aaaggtattt ttgattattt
    19201 cttagataca gtggggagta atgtaacatt atacggttta aaacgtctaa attatcaagg
    19261 tgttgctact gtatgtggaa atgtagcagg aaattcactt aacgctaata tattaccgtt
    19321 tattcttaga ggtattaaat taattggcat tgattctgta tatgttgatc ataatatccg
    19381 tgaagatata tggagtaagt tagcaaatga atggaatata ggaaattcac ttctatacaa
    19441 tgaaattgga tttgaagaat tctataaaac gatagatcag cttttaaaag gacaacattt
    19501 aggaagaact attttaaaag tat
//
