LOCUS       CP006623               31004 bp    DNA     circular BCT 26-JUL-2016
DEFINITION  Enterococcus faecium Aus0085 plasmid p3, complete sequence.
ACCESSION   CP006623
VERSION     CP006623.1
DBLINK      BioProject: PRJNA193299
            BioSample: SAMN02604219
KEYWORDS    .
SOURCE      Enterococcus faecium Aus0085
  ORGANISM  Enterococcus faecium Aus0085
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 31004)
  AUTHORS   Lam,M.M., Seemann,T., Tobias,N.J., Chen,H., Haring,V., Moore,R.J.,
            Ballard,S., Grayson,L.M., Johnson,P.D., Howden,B.P. and Stinear,T.P.
  TITLE     Comparative analysis of the complete genome of an epidemic hospital
            sequence type 203 clone of vancomycin-resistant Enterococcus faecium
  JOURNAL   BMC Genomics 14, 595 (2013)
   PUBMED   24004955
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31004)
  AUTHORS   Lam,M.M.C., Seemann,T., Tobias,N.J., Chen,H., Haring,V., Moore,R.J.,
            Ballard,S., Grayson,L., Johnson,P.D.R., Howden,B.P. and Stinear,T.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-AUG-2013) Microbiology and Immunology, University of
            Melbourne, Royal Parade, Parkville, Victoria 3010, Australia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method       :: Newbler v. 2.8
            Genome Coverage       :: 40X
            Sequencing Technology :: 454
            ##Genome-Assembly-Data-END##
            Source Bacteria and DNA are available from Professor Benjamin
            Howden, Austin Hospital, Melbourne, Australia
            (benjamin.Howden@austin.org.au).
FEATURES             Location/Qualifiers
     source          1..31004
                     /organism="Enterococcus faecium Aus0085"
                     /mol_type="genomic DNA"
                     /strain="AUS0085"
                     /db_xref="taxon:1305849"
                     /plasmid="p3"
     gene            1..1425
                     /gene="rep"
                     /locus_tag="EFAU085_p3001"
     CDS             1..1425
                     /gene="rep"
                     /locus_tag="EFAU085_p3001"
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="AGS77119.1"
                     /translation="MKPAGHIDSSRSGAIFAYRSKQLMNVGRGMVITSEEAILENEKKL
                     THWTPNTYRFGTYADDYRTVVKGHSEKNLSQINTFVVDIDSKENHQGEIILACLDQVGY
                     MPTLILESDHGYQVYFVLKTPGYVTKKSNFKVIDVAKKISKTIRLQLAEKLSGVDLGCN
                     HFGIARFPQENNIVFKEMNYQYSFADWIQWSMKLESDQKTKEDRERKLIVFPEKKEIRQ
                     VDEPWFDMLLHKANIVGGEGRLGRNNVIFTLSLAYYSSGYALDTCEYNMFTFNERLQEP
                     LSEAELVKIVRSAYSGNYQAASREFIIELCQQWVSPTLKNNDLFIQRRGWWKFKKPRDQ
                     RKYSHKNEWKEDLLAYLSEKSLASEPYLNLSKKELASQLTMPKRTLDKILNELREENKV
                     FYKVTRGRNGGMIIASVKTLFARVIQLSKEKRLDYSTRITEVFGLNESLVEETFRQLST
                     PLNPLKEVNLFEVDTG"
                     /name="rep"
     gene            1539..1856
                     /gene="prgN"
                     /locus_tag="EFAU085_p3002"
     CDS             1539..1856
                     /gene="prgN"
                     /locus_tag="EFAU085_p3002"
                     /codon_start=1
                     /transl_table=11
                     /product="replication control protein PrgN"
                     /protein_id="AGS77120.1"
                     /translation="MYHGGSCMSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTL
                     SSWVTREKTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYI
                     Q"
                     /name="prgN"
     gene            complement(1880..2839)
                     /locus_tag="EFAU085_p3003"
     CDS             complement(1880..2839)
                     /locus_tag="EFAU085_p3003"
                     /codon_start=1
                     /transl_table=11
                     /product="Integrase core domain protein"
                     /protein_id="AGS77121.1"
                     /translation="MTYTHLTTDELVMIESYFKINQSVAKTAHFLNRSRQTIHKVYLFF
                     KQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIRCS
                     ARTIYRMFKKGLFNPSDLPMKGKRKPNGHQERRGKQAFRRSIHEREKDYSQFSNEFGHL
                     EGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIENKLNHWFESVPKNLFKSITF
                     DCGKEFSNWKQISNANDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNSVDESF
                     IQSVASKRNNIPRKSLNYRTPLEVFLSYVSIDDLSNLI"
                     /name="Integrase core domain protein"
     gene            3022..3873
                     /locus_tag="EFAU085_p3004"
     CDS             3022..3873
                     /locus_tag="EFAU085_p3004"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AGS77122.1"
                     /translation="MKSDDWIEHTWLPLKRNSKRKKFWVLQLWPLGKLCSYGARLILDL
                     TVYSIGVFGTAYYLINDPNRIAASDIFTVLMTLIFVMLLSIFTQLVMQFTRQKLTAGKL
                     FKSLFDLIVVNAILATLIKQIEQSGRTTKGVKDFLLTFIHFVNGHMYLFEVGIILFFVG
                     YVSTKLIKRSIEKEIEIDLIPTLLGYEYNVDFGRYDELINTDIVHTSIHESTVKGIRSI
                     LKNGQEMKAIDRRKEIYNFYEVEASLRYGIGKLWLDGSNIRQNKPYIFWNSSDLELPMK
                     DK"
                     /name="hypothetical protein"
     gene            3876..4106
                     /locus_tag="EFAU085_p3005"
     CDS             3876..4106
                     /locus_tag="EFAU085_p3005"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AGS77123.1"
                     /translation="MENRLKMIPLYRIVLIVGMELKTLKKEQLFKVKERHNQLLCSKTG
                     TMNIEYRTEYLELTNQTDFLLIRKQQEQEKN"
                     /name="hypothetical protein"
     gene            4398..4511
                     /locus_tag="EFAU085_p3006"
     CDS             4398..4511
                     /locus_tag="EFAU085_p3006"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AGS77124.1"
                     /translation="MEVRIRNVDEKIVREIDRRCDERFCCKVLNLLSNKVE"
                     /name="hypothetical protein"
     gene            4521..5219
                     /locus_tag="EFAU085_p3007"
     CDS             4521..5219
                     /locus_tag="EFAU085_p3007"
                     /codon_start=1
                     /transl_table=11
                     /product="Integrase core domain protein"
                     /protein_id="AGS77125.1"
                     /translation="MAGGMTMNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRG
                     INVSHTTIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGL
                     TLDIWLRKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHR
                     TIKYLNNLIEQDYRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCT
                     EIKVLLGIPA"
                     /name="Integrase core domain protein"
     gene            5508..5723
                     /locus_tag="EFAU085_p3008"
     CDS             5508..5723
                     /locus_tag="EFAU085_p3008"
                     /codon_start=1
                     /transl_table=11
                     /product="Omega Transcriptional Repressor"
                     /protein_id="AGS77126.1"
                     /translation="MIVGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETA
                     KNGGNVKEVMDQALEEYIRKYLPDKL"
                     /name="Omega Transcriptional Repressor"
     gene            5740..6012
                     /locus_tag="EFAU085_p3009"
     CDS             5740..6012
                     /locus_tag="EFAU085_p3009"
                     /codon_start=1
                     /transl_table=11
                     /product="Bacterial epsilon antitoxin"
                     /protein_id="AGS77127.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELNKNDSQLLEVN
                     LLNQLKLAKRVNLFDYSLEELQAVHEYWRSMNRYSKQVLNKEKVA"
                     /name="Bacterial epsilon antitoxin"
     gene            6014..6877
                     /locus_tag="EFAU085_p3010"
     CDS             6014..6877
                     /locus_tag="EFAU085_p3010"
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin"
                     /protein_id="AGS77128.1"
                     /translation="MANIVNFTDKQFENRLNDNLEELIQGKKAVESPTAFLLGGQPGSG
                     KTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAIIS
                     RLSDQGYNLVIEGTGRTTDVPIQTATMLQAKGYETKMYVMAVPKINSYLGTIERYETMY
                     ADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETPSISP
                     KETLEKELNRKVSGKEIQPTLERIEQKMVLNKHQETPEFKAIQQKLESLQPPTPPIPKT
                     PKLPGI"
                     /name="zeta toxin"
     gene            complement(7055..7195)
                     /locus_tag="EFAU085_p3011"
     CDS             complement(7055..7195)
                     /locus_tag="EFAU085_p3011"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AGS77129.1"
                     /translation="MSKYCLFLIVIYYLTGGNNSMSRFCKFGKLHVTKGNVDKLLGIGH
                     L"
                     /name="hypothetical protein"
     gene            complement(7140..7877)
                     /gene="erm"
                     /locus_tag="EFAU085_p3012"
     CDS             complement(7140..7877)
                     /gene="erm"
                     /locus_tag="EFAU085_p3012"
                     /EC_number="2.1.1.184"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA adenine N-6-methyltransferase"
                     /protein_id="AGS77130.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLTT
                     KLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIPYH
                     LSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAECFH
                     PKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHAKVNN
                     LSTVTYEQVLSIFNSYLLFNGRK"
                     /name="erm"
     gene            complement(8627..9412)
                     /gene="aphA"
                     /locus_tag="EFAU085_p3013"
     CDS             complement(8627..9412)
                     /gene="aphA"
                     /locus_tag="EFAU085_p3013"
                     /EC_number="2.7.1.95"
                     /codon_start=1
                     /transl_table=11
                     /product="Aminoglycoside 3'-phosphotransferase"
                     /protein_id="AGS77131.1"
                     /translation="MRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLKMTDS
                     RYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEYEDEQS
                     PEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWEEDTPFK
                     DPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKWYDIAFCV
                     RSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
                     /name="aphA"
     gene            9884..10792
                     /locus_tag="EFAU085_p3014"
     CDS             9884..10792
                     /locus_tag="EFAU085_p3014"
                     /codon_start=1
                     /transl_table=11
                     /product="ISEfm1, transposase"
                     /protein_id="AGS77132.1"
                     /translation="MRSSKYTEHYTDTFITFKEIMRTVSNIYHNCVPDKIKNRRNTDQL
                     KQRDTVIIACVIWGIINGYTSQRATYRAVCSVLFPNGDFPSRSRFTRLSSNLAYTIKII
                     RYFFIKKLTKGELVGIIDSFPSPLCKPVRNRQAKLLNQIAKVGYNSTKKSYFYGLKIHM
                     IVTKTGFPITYSITNPGVHDVKVLETLSEEANLPNILGDKGYISHKIHEKLALKGITIS
                     VPPRKNMDKSEKLDHSLLGKQRKTVETVFSSLEKLGCQNFNSRSVKGLESRFESILLAY
                     SVLLSRAQRRFGGTLRYSLGY"
                     /name="ISEfm1, transposase"
     gene            complement(10795..11043)
                     /gene="sat4"
                     /locus_tag="EFAU085_p3015"
     CDS             complement(10795..11043)
                     /gene="sat4"
                     /locus_tag="EFAU085_p3015"
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin acetyltransferase"
                     /protein_id="AGS77133.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEAP
                     YLKSYQDEEDEEDEEADCLEYIDNTDKIIYLLTRGAS"
                     /name="sat4"
     gene            complement(11040..11948)
                     /gene="aadE"
                     /locus_tag="EFAU085_p3016"
     CDS             complement(11040..11948)
                     /gene="aadE"
                     /locus_tag="EFAU085_p3016"
                     /EC_number="2.7.7.-"
                     /codon_start=1
                     /transl_table=11
                     /product="Streptomycin adenyltransferase"
                     /protein_id="AGS77134.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYDI
                     TYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLTLL
                     PLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNVTPY
                     VIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYISEDLW
                     EKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRDMYKKY
                     TGKTGCLDSTYAADIEERREQ"
                     /name="aadE"
     gene            complement(11981..12715)
                     /locus_tag="EFAU085_p3017"
     CDS             complement(11981..12715)
                     /locus_tag="EFAU085_p3017"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain protein"
                     /protein_id="AGS77135.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGKR
                     VLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDFPE
                     ESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNEKGE
                     ILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPENMMD
                     IPGMADEMRRPMMLIVSAKKKM"
                     /name="methyltransferase domain protein"
     gene            complement(12696..13565)
                     /locus_tag="EFAU085_p3018"
     CDS             complement(12696..13565)
                     /locus_tag="EFAU085_p3018"
                     /codon_start=1
                     /transl_table=11
                     /product="Nucleotidyltransferase domain protein"
                     /protein_id="AGS77136.1"
                     /translation="MVGNVIQIVTEKLSSLPFIEGIVLGGSRARSTHTENSDIDIGIYY
                     NSDSFDLTAINQIATELDDENRNNLVVPPGAWGDWVNGGGWLVINGCHVDLILRDIKRV
                     EQIIKDTEQGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAEIYPTA
                     LKKSLMNFFIFEAEFSLMFVKANAGAEDKYYIAGHVFRIISCLNQVLFACNNAYCINEK
                     KAIKLLETFEYKPEKYAERVNHIFEVLGLSLFECYDMTEKLYKEVNEIVSEINNFLNEE
                     SSDERKQI"
                     /name="Nucleotidyltransferase domain protein"
     gene            complement(13580..13804)
                     /locus_tag="EFAU085_p3019"
     CDS             complement(13580..13804)
                     /locus_tag="EFAU085_p3019"
                     /codon_start=1
                     /transl_table=11
                     /product="toxin-antitoxin system, antitoxin component, Xre
                     family"
                     /protein_id="AGS77137.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLDE
                     LKAIADVLGVKFVQAFILPDGDEIKISNE"
                     /name="toxin-antitoxin system, antitoxin component, Xre
                     family"
     gene            complement(13947..14615)
                     /locus_tag="EFAU085_p3020"
     CDS             complement(13947..14615)
                     /locus_tag="EFAU085_p3020"
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase protein"
                     /protein_id="AGS77138.1"
                     /translation="MQAQEEIYRRSNIYTGEGKNKRIYSSKYALSAITFCGYCGDIYRR
                     TYWNIHGRKEFVWRCVTRIEQGPEVCKNRTVKEDELYGAVMTAINKLLAGGNNMIKTLE
                     ENIHAVIGETTEYQISEINTLLDEKQKELIKLANKGQDYEYLVDEIDEMRDKRQTLLVE
                     DASLSGENERINELIEFIRKNKFRTLEYDDKLVRKIIQNVKVYEDHFVIAFKPGIEMEI
                     "
                     /name="resolvase protein"
     gene            complement(15456..15665)
                     /locus_tag="EFAU085_p3021"
     CDS             complement(15456..15665)
                     /locus_tag="EFAU085_p3021"
                     /codon_start=1
                     /transl_table=11
                     /product="Lincosamide nucleotidyltransferase"
                     /protein_id="AGS77139.1"
                     /translation="MSKNLEKEISLENYKKFAKTTARLDKVELFEAYKNSLLLVMDLQS
                     HLIEQYNLKVTHDILERLLNYISE"
                     /name="Lincosamide nucleotidyltransferase"
     gene            complement(15679..16257)
                     /locus_tag="EFAU085_p3022"
     CDS             complement(15679..16257)
                     /locus_tag="EFAU085_p3022"
                     /codon_start=1
                     /transl_table=11
                     /product="Lincosamide nucleotidyltransferase"
                     /protein_id="AGS77140.1"
                     /translation="MLKQKELIANVKNLTESDERITACMMYGSFTKGEGDQYSDIEFYI
                     FLKDSITSNFDSSNWLFDVAPYLMLYKNEYGTEVVIFDNLIRGEFHFLSEKDMNIIPSF
                     KDSGYIPDTKAMLIYDETGQLENYLSEISGARPNRLTEENANFLLCNFSNLWLMGINVL
                     KRGEYARSLELLSQLQKNTLQLIRMAEKC"
                     /name="Lincosamide nucleotidyltransferase"
     gene            complement(16311..17795)
                     /locus_tag="EFAU085_p3023"
     CDS             complement(16311..17795)
                     /locus_tag="EFAU085_p3023"
                     /codon_start=1
                     /transl_table=11
                     /product="drug resistance ABC transporter ATP-binding
                     protein"
                     /protein_id="AGS77141.1"
                     /translation="MSLINVSNLTFSYEGSYDNIFENVSFQIDTDWKLGFIGRNGRGKT
                     TFLNLLLGKYAYSGNISSTVKFEYFPYDVEDKSLYTIEVMKSICTEFMDWEIFREISLL
                     DVQEDALYRPFNTLSNGEQTKVLLAALFLTASCFLLIDEPTNHLDIDARNVVQNYLKRK
                     KGFILVSHDRSLLDQCVDHILSINKTNIEIQKGNFTSWWENKTLQDNFELAENKKLLKE
                     IGRLSYAAKRSSNWSNKVEKSKYGTTNSGSKLDKGYVGHKAAKAMKRAKNIESRHQEAV
                     LQKSELLHNIEQYDDLKISPLEFHKECLIEANDLSLSYGDKEVCSNLNFRVNIGDRVAI
                     IGKNGSGKSSILKLINGDDIKFTGNFMLASGLKISYISQDTSYLKGNLSEFAYNNKIDE
                     TLFKTILRKLDFNREQFDKNMVDFSAGQKKKVLIAKSLCESAHLYIWDEPLNYIDIFSR
                     IQIEKMILEYCPTLLFVEHDDAFCNNICTKNINLGL"
                     /name="drug resistance ABC transporter ATP-binding protein"
     gene            complement(18238..18636)
                     /locus_tag="EFAU085_p3024"
     CDS             complement(18238..18636)
                     /locus_tag="EFAU085_p3024"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AGS77142.1"
                     /translation="MANKEPFLQALQKNIATILNEENDNATNDIDSKLEELQQQLLIQA
                     KSKNDYEDVADEIYHLRELKQNALVENAEREGKRQRIAEMTDFFNEQSCELEEYDEQLV
                     RRLIEKVTVFHDKFAVEFKSGVEIDVEG"
                     /name="hypothetical protein"
     gene            complement(18712..19170)
                     /locus_tag="EFAU085_p3025"
     CDS             complement(18712..19170)
                     /locus_tag="EFAU085_p3025"
                     /codon_start=1
                     /transl_table=11
                     /product="Integrase core domain protein"
                     /protein_id="AGS77143.1"
                     /translation="MDETYIKIKGRWHYLYRAIDADGLTLDIWLRKKRDTQAAYAFLKR
                     LVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLNNLIEQDHRPVKRRNK
                     FYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLLGIPA"
                     /name="Integrase core domain protein"
     gene            complement(19685..20842)
                     /locus_tag="EFAU085_p3026"
     CDS             complement(19685..20842)
                     /locus_tag="EFAU085_p3026"
                     /note="IS605 OrfB family"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="AGS77144.1"
                     /translation="MNFMEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKA
                     YEEVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPR
                     FKSKKNPVQSYTTNNQNGTVALIDSKFIKVPKLKSLVRIKLHRQPKGIIKSATISRHSS
                     GKYYISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDNNKFTSKMEKKLKREQR
                     KLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLNKLSTEMIKNHDIIC
                     IEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIKVDKWFPSSQICSECG
                     HKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLHSMGLA"
                     /name="transposase"
     gene            complement(20850..21254)
                     /locus_tag="EFAU085_p3027"
     CDS             complement(20850..21254)
                     /locus_tag="EFAU085_p3027"
                     /codon_start=1
                     /transl_table=11
                     /product="Transposase"
                     /protein_id="AGS77145.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERISE
                     SYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLWKEMF
                     WSKSFCLLTTGGAPIDVIKKYIQNQGNNHK"
                     /name="Transposase"
     gene            21491..21703
                     /locus_tag="EFAU085_p3028"
     CDS             21491..21703
                     /locus_tag="EFAU085_p3028"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AGS77146.1"
                     /translation="MAVWQIQLKERGAYGLISLSDVLCRKEMPDLFSLDQIIAIIGAAA
                     VVITAVAKASDSILAWLKFKKEQKK"
                     /name="hypothetical protein"
     gene            21865..22383
                     /gene="yfbU"
                     /locus_tag="EFAU085_p3029"
     CDS             21865..22383
                     /gene="yfbU"
                     /locus_tag="EFAU085_p3029"
                     /codon_start=1
                     /transl_table=11
                     /product="YfbU domain protein"
                     /protein_id="AGS77147.1"
                     /translation="MDKFNRLTLINQFEILKALNPNEEKYYAEKIEILTEGYEYHYSEI
                     FENISDPLPEEDSRFVLDILNMYRDITFSKNKLKDINSIDNYYIQFKGFDFNSSTEFKL
                     ALYAQFFIEKLNRFQEIVEDSDFNTFNSHKPMRGTYIKFLENYNDLKSTNNYQFGNLSY
                     EMISKVLSL"
                     /name="yfbU"
     gene            22390..22902
                     /locus_tag="EFAU085_p3030"
     CDS             22390..22902
                     /locus_tag="EFAU085_p3030"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AGS77148.1"
                     /translation="MKLNSINDLFAIIGVIANILFSCLNFRFTQKNKKNKLSIEQMKKD
                     IETDLKNDHKERRKIEEYTSLMEKCKATDAIFSFLRKSDEIITRENIDLENEISKLESI
                     FSDINSLKYLIVEENSDSFLEFEKYLTDLIDNRNNELMRQNIARFLTKLVSEWKSIISQ
                     NMDKLRY"
                     /name="hypothetical protein"
     gene            23173..23796
                     /locus_tag="EFAU085_p3031"
     CDS             23173..23796
                     /locus_tag="EFAU085_p3031"
                     /codon_start=1
                     /transl_table=11
                     /product="Resolvase protein"
                     /protein_id="AGS77149.1"
                     /translation="MYLAYLRVSSDDQSLARQHKLIENWSVKNNIAEDDLKIFEEKVSG
                     KNIENRPELQELISFIRERDTIIIPSLDRLARNSKDTKDLLQLFRSKGASIEILDLPSF
                     NGVTDPALRDLLTNLVIEVFSYVAENERKKIKERQKQGIEIAKKNGRYTGKKIQYHANA
                     TGKNKLIYDEIVDGLKKKETISKIAKNAGVTRKTVYRVKRDLGM"
                     /name="Resolvase protein"
     gene            23886..24572
                     /locus_tag="EFAU085_p3032"
     CDS             23886..24572
                     /locus_tag="EFAU085_p3032"
                     /codon_start=1
                     /transl_table=11
                     /product="Transposase, IS1216"
                     /protein_id="AGS77150.1"
                     /translation="MTMNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVS
                     HTTIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKY
                     LNNLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKV
                     LLGIPA"
                     /name="Transposase, IS1216"
     gene            24770..25375
                     /gene="fic"
                     /locus_tag="EFAU085_p3033"
     CDS             24770..25375
                     /gene="fic"
                     /locus_tag="EFAU085_p3033"
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="AGS77151.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTFK
                     GLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEIIKK
                     YVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDLEIR
                     YLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
                     /name="fic"
     gene            25391..25963
                     /locus_tag="EFAU085_p3034"
     CDS             25391..25963
                     /locus_tag="EFAU085_p3034"
                     /codon_start=1
                     /transl_table=11
                     /product="Resolvase protein"
                     /protein_id="AGS77152.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENCVEKKNIFSEKFTGTKRDR
                     PKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTSMG
                     RMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELLTSG
                     KSYKEVEAITGFSRSTLFRIKKKIEES"
                     /name="Resolvase protein"
     gene            26083..26235
                     /locus_tag="EFAU085_p3035"
     CDS             26083..26235
                     /locus_tag="EFAU085_p3035"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AGS77153.1"
                     /translation="MVTVKGKVIKGMLATLTILGYHHIFIMNDLFVYQTTHIVQRKSRL
                     GTWLF"
                     /name="hypothetical protein"
     gene            complement(26436..26810)
                     /locus_tag="EFAU085_p3036"
     CDS             complement(26436..26810)
                     /locus_tag="EFAU085_p3036"
                     /codon_start=1
                     /transl_table=11
                     /product="Integrase core domain protein"
                     /protein_id="AGS77154.1"
                     /translation="MTVDCVIQTLNKAKIHYHIPEGMILHTDLGSQYTAREVEQWLKTN
                     KIRHSYSRKGTPYDNAGIESFHASLKKEEVYTTSYSDFEEANRALFSYIEGFYNRNRIH
                     SSIHYLTPQEFEELAKEKMA"
                     /name="Integrase core domain protein"
     gene            complement(27109..27945)
                     /locus_tag="EFAU085_p3037"
     CDS             complement(27109..27945)
                     /locus_tag="EFAU085_p3037"
                     /codon_start=1
                     /transl_table=11
                     /product="Integrase core domain protein"
                     /protein_id="AGS77155.1"
                     /translation="MCRILGLSRQSYYYQSKPKKDESELEEVVAEEFIRSRKAYGSRKI
                     KKALSKRGIQISRRKISRIMKNRGLKSSYTVAYFKVHHSTCNEAKTTNVLNRKFLRDNP
                     LEAIVTDLTYVRVGKKWNYVCFILDLFNREILGYSCGEHKDAVLVKKAFSRIKQPLTEV
                     EIFHTDRGKEFDNQAIDELLTTFDINRSLSHKGCPFDNAVAESTYKSLKVEFVYQYTFE
                     TLQQLDLELFDYVNWWNHLRLHGTLGYETPVGYRNQRLAQRILDNELGCANASEAV"
                     /name="Integrase core domain protein"
     gene            complement(27981..28310)
                     /locus_tag="EFAU085_p3038"
     CDS             complement(27981..28310)
                     /locus_tag="EFAU085_p3038"
                     /codon_start=1
                     /transl_table=11
                     /product="Transposase"
                     /protein_id="AGS77156.1"
                     /translation="MCRLEENIPGGIFMSKRTRRTFSQEFKQQIVNLYLAGKPRVEIIR
                     EYELTASAFDKWVKQSKTSGSFKEKDNLTPEQKELLELRKRNQQLEMENDILKQAALIF
                     GRRDK"
                     /name="Transposase"
     gene            complement(28312..28566)
                     /locus_tag="EFAU085_p3039"
     CDS             complement(28312..28566)
                     /locus_tag="EFAU085_p3039"
                     /codon_start=1
                     /transl_table=11
                     /product="Transposase"
                     /protein_id="AGS77157.1"
                     /translation="MTATEIRNNKLKKKISTIFFTNKQRYGATKIHQVLLKEGISVSLK
                     HVQKLMKQLNLRSIVVKKYRPQRSNKPIMDRLQLTRQKN"
                     /name="Transposase"
     gene            complement(28677..28931)
                     /locus_tag="EFAU085_p3040"
     CDS             complement(28677..28931)
                     /locus_tag="EFAU085_p3040"
                     /codon_start=1
                     /transl_table=11
                     /product="Transposase"
                     /protein_id="AGS77158.1"
                     /translation="MTRYEENFKQMIVELNQTGRSVRGLAKEYGLSEATIYKWKNLYLP
                     DQSTGLTGKEVAELRKENARLNEELEILKKAAAIFSRKT"
                     /name="Transposase"
     gene            complement(29124..29399)
                     /locus_tag="EFAU085_p3041"
     CDS             complement(29124..29399)
                     /locus_tag="EFAU085_p3041"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AGS77159.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVDP
                     PVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
                     /name="hypothetical protein"
     gene            complement(29371..30324)
                     /locus_tag="EFAU085_p3042"
     CDS             complement(29371..30324)
                     /locus_tag="EFAU085_p3042"
                     /codon_start=1
                     /transl_table=11
                     /product="putative PrgP protein"
                     /protein_id="AGS77160.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLFE
                     KDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGSPG
                     SEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAADYII
                     AMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQKTID
                     KYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYYEQHGD
                     IEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
                     /name="putative PrgP protein"
     ARG             complement(8631..9421)
                     /name="aph(3')-IIIa"
                     /gene="aph(3')-IIIa"
                     /gene_name="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(11044..11948)
                     /name="ant(6)-Ia"
                     /gene="ant(6)-Ia"
                     /gene_name="aminoglycoside nucleotidyltransferase
                     ANT(6)-Ia"
                     /tool="amrfinderplus"
                     /drug_class="AMINOGLYCOSIDE"
                     /identity="100.0"
                     /coverage="100.0"
     ARG             complement(7144..7877)
                     /name="erm(B)"
                     /gene="erm(B)"
                     /gene_name="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /tool="amrfinderplus"
                     /drug_class="LINCOSAMIDE/MACROLIDE/STREPTOGRAMIN"
                     /identity="99.59"
                     /coverage="100.0"
     ARG             complement(16315..17795)
                     /name="lsa(E)"
                     /gene="lsa(E)"
                     /gene_name="ABC-F type ribosomal protection protein Lsa(E)"
                     /tool="amrfinderplus"
                     /drug_class="LINCOSAMIDE/STREPTOGRAMIN"
                     /identity="99.8"
                     /coverage="100.0"
     ARG             complement(16312..17795)
                     /name="lsaE"
                     /gene="lsaE"
                     /gene_name="lsa-type ABC-F protein"
                     /tool="rgi"
                     /drug_class="lincosamide antibiotic; streptogramin
                     antibiotic; pleuromutilin antibiotic"
                     /identity="99.8"
                     /coverage="100.0"
     ARG             complement(15680..16257)
                     /name="lnuB"
                     /gene="lnuB"
                     /gene_name="lincosamide nucleotidyltransferase (LNU)"
                     /tool="rgi"
                     /drug_class="lincosamide antibiotic"
                     /identity="99.48"
                     /coverage="71.91"
     ARG             complement(15457..15665)
                     /name="lnuB"
                     /gene="lnuB"
                     /gene_name="lincosamide nucleotidyltransferase (LNU)"
                     /tool="rgi"
                     /drug_class="lincosamide antibiotic"
                     /identity="100.0"
                     /coverage="25.84"
     ARG             complement(7141..7877)
                     /name="ErmB"
                     /gene="ErmB"
                     /gene_name="Erm 23S ribosomal RNA methyltransferase"
                     /tool="rgi"
                     /drug_class="macrolide antibiotic; lincosamide antibiotic;
                     streptogramin antibiotic; streptogramin A antibiotic;
                     streptogramin B antibiotic"
                     /identity="98.78"
                     /coverage="98.79"
     ARG             complement(10796..11043)
                     /name="SAT-4"
                     /gene="SAT-4"
                     /gene_name="streptothricin acetyltransferase (SAT)"
                     /tool="rgi"
                     /drug_class="nucleoside antibiotic"
                     /identity="98.68"
                     /coverage="45.56"
     ARG             complement(11041..11948)
                     /name="aad(6)"
                     /gene="aad(6)"
                     /gene_name="ANT(6)"
                     /tool="rgi"
                     /drug_class="aminoglycoside antibiotic"
                     /identity="100.0"
                     /coverage="109.42"
     Typing          2..1425
                     /name="rep_cluster_185"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="99.86"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 atgaaacctg caggtcatat tgattccagt aggagtggtg ctatctttgc gtaccgtagc
       61 aagcaattaa tgaatgttgg gcgtggtatg gtcattactt cggaagaagc tattttagag
      121 aacgaaaaga aactaacgca ttggacacct aatacctatc gctttggtac ttatgcggat
      181 gattatcgaa cagtggttaa aggtcattct gagaaaaact taagtcaaat caacacattt
      241 gtagttgata tcgattcaaa agagaaccat caaggcgaaa ttattttagc ctgtttagat
      301 caagtgggct acatgccaac gctaatttta gaatcagatc atggttatca agtttatttt
      361 gtactaaaga caccaggcta tgtcacaaag aaaagcaatt tcaaggtgat cgatgtagca
      421 aaaaaaattt caaaaacaat tcgtctacag ttggctgaaa aattgtccgg agtggatcta
      481 ggatgtaacc acttcggaat tgctcgattc ccacaagaaa ataatattgt ttttaaagaa
      541 atgaactatc agtattcttt tgctgactgg attcaatggt cgatgaagct tgaatcagat
      601 caaaaaacaa aagaagatcg agaacgaaaa ctaattgtct ttcctgagaa aaaagaaatt
      661 cgtcaagtag atgaaccgtg gttcgatatg ttacttcata aagcaaacat cgtcggcgga
      721 gaaggacgtc ttggtcgaaa taatgtgatt ttcacgcttt ctttagctta ttactcttca
      781 ggttatgcat tggatacttg cgaatacaat atgttcacat tcaacgaacg gttacaggaa
      841 ccgctatctg aagcagaatt agtaaagatt gtacgtagtg cttattctgg taattatcaa
      901 gcagcaagca gagaattcat tattgaattg tgccagcaat gggtttcacc aaccttaaaa
      961 aataatgatc tgttcattca acgacgtggc tggtggaaat ttaaaaagcc acgagatcaa
     1021 agaaaatata gtcataaaaa tgaatggaaa gaagatctat tggcttatct aagcgaaaaa
     1081 agtcttgcta gtgagcctta tttgaacctg tcaaaaaaag aattggcttc acaactaacg
     1141 atgcccaagc gaacacttga taagatctta aatgagttac gagaggagaa taaagtcttc
     1201 tacaaggtaa cacgaggaag aaatggcgga atgatcattg cttcagtcaa aacgttgttc
     1261 gcgagggtta ttcaactaag taaagaaaag agactagatt attcaacaag gatcacagag
     1321 gtatttggac tcaacgagag cttagtagaa gagacattta gacaattatc aacccccttg
     1381 aaccctctta aagaagtgaa tctttttgaa gtagatacag gttgaaaaat aaaaggtgca
     1441 aattgcctta tacaatatat ctatgatact tctgtaggtg ttgctccctt tgcctagcta
     1501 cgtgtaggtg gtatacttat aactgcgtat gcagtcttat gtatcatgga ggaagttgta
     1561 tgtcgttaaa aaattatgtc tattcacatc ctgttaatgt gtttatcatt ggtcgtttgg
     1621 gattatctgt ggaagtgttc tgtgagcttt atggttttaa gcaggggact ttgtcttctt
     1681 gggttaccag ggaaaaaaca gttgcttctt tgccgattga gtttcttcat gggttgtcct
     1741 tagcttctgg ggagactatg gatcaggtat atgattgttt gtgtgtgtta gagcaggagt
     1801 atattgagta taaaatagct aacgagttaa gaaaaaggaa gaagtatatc cagtagtagt
     1861 ttttatttac tcttaattgt caaattaagt tagacaaatc atcaatactt acgtaactca
     1921 aaaatacttc caaaggtgtt cgataattca gtgattttct aggaatatta tttcgtttcg
     1981 atgcgacaga ttgaataaaa gattcatcta ctgaattgaa atccatagat ttcaataaac
     2041 catctctacg taacaatccg ttagaattct cgtttaggcc tctttgagac ggcgttcctg
     2101 gatcagcgaa ataaatggca atatcattgg cattactgat ctgtttccaa tttgaaaatt
     2161 cttttccaca atcaaaagta attgatttga aaagattttt cggtacagat tcaaaccaat
     2221 gatttaattt gttttcaata tcaatcgctt gtctaccaca cggtttcaat gtgatgataa
     2281 cttttgataa tcgctcaact aaggtaatta cagcactttt atgtttcaaa cctacgatag
     2341 tgtcaccttc aaggtgacca aactcatttg agaattggct ataatctttt tcacgttcat
     2401 gaatagagcg acggaaagct tgttttccac gtctttcttg atgtccattt ggtttacgct
     2461 tgcctttcat cggtaagtca gaaggattaa atagcccctt tttgaacata cgataaatgg
     2521 tacgagcaga acaacgaata ggaaacgctg cacgaccaac aatcacatcg ggtgtccatc
     2581 cttgaacaac ctttctttga atatattctg attgttcctc aggtaaaaca agcgggcgtc
     2641 taccacagtt tgatttgttt ttcttatact gttgatagta ctctaaggct gattttcctt
     2701 gcttgaagaa caggtatact ttatggatcg tttgtcttga acgattcaag aaatgcgcag
     2761 ttttcgcaac agattgattt attttgaaat aagactctat cattacaagt tcatccgttg
     2821 taagatgggt ataggtcatt tgtactcact ccttataatt ctttggacgg aactattttg
     2881 agtgtagcac aaatgacttt tttagttgtc tagcttaatt ttacaatcgg cgtacttaaa
     2941 aaattggttc attgagcaac ctatcgctgc taaagtagca aaggaaaacg ttaaaggaaa
     3001 gaatttaggg aagaaatcga aatgaaatcg gacgactgga ttgaacacac ctggcttcct
     3061 ctgaaaagaa atagcaaacg aaagaaattt tgggtattgc aattatggcc attaggaaaa
     3121 ctttgtagtt acggggcacg acttattctt gatttaaccg tttactcgat tggagtattt
     3181 ggaacggctt attacttgat aaatgatccc aataggattg cagcatcaga catttttaca
     3241 gtgctaatga cgttgatttt tgtcatgcta ttgtctattt ttactcaatt agtcatgcaa
     3301 tttaccaggc aaaaattaac agcaggaaaa cttttcaaaa gcctattcga tttaattgtt
     3361 gtaaatgcaa ttctagcgac tttaataaaa caaattgaac aatctggaag aacaacaaaa
     3421 ggagtgaagg attttttatt gacgtttatt cactttgtaa atggacacat gtatttgttt
     3481 gaagtgggta ttattctctt ttttgtcggg tatgtatcca cgaaacttat taaacgttca
     3541 attgaaaaag aaattgaaat tgacctgatt ccgacacttc ttggttatga gtacaatgtt
     3601 gattttggaa gatatgacga attgatcaat acggatatcg ttcacacgag tatccatgaa
     3661 tctactgtta agggcatcag atctatttta aaaaatggcc aggaaatgaa agcaatagat
     3721 cgaagaaaag agatctacaa tttttatgaa gtcgaagcaa gcctacgata tggcatcgga
     3781 aaattgtggt tagatggaag taatattcgt caaaacaaac catacatttt ttggaacagt
     3841 agtgatttag aacttccaat gaaagataaa taattatgga gaatcgtttg aaaatgattc
     3901 ctctatacag gattgtgctt atagttggca tggagttaaa aaccttaaag aaggagcagt
     3961 tattcaaagt gaaagaacgt cataatcagt tactatgtag taaaacgggt acgatgaaca
     4021 ttgaataccg aacagaatat ttagaattaa cgaatcaaac tgattttttg ttgattcgaa
     4081 agcaacaaga gcaagaaaaa aattaatggc tacttatagc caattgattg atgaatggga
     4141 acaattcaag gaatctaaaa ttccagaacg tctctaaaag cctttatttg taaagagcat
     4201 aaggaaacgt gggaacactt tttaaaaaaa gtgttccaat aggctgtgcc tattacgttt
     4261 ctcaaaaata aatgtgggaa caaaatattt aaaaatagga tagtgaaagg atagtgaagg
     4321 atagtaaaag gagggtagta ggatagcaaa aaggataggc tccttttcgc tatccttttt
     4381 aaattggagg aattaatatg gaagtaagaa taagaaatgt ggatgagaaa atcgtaagag
     4441 aaattgatcg aagatgtgac gaacggttct gttgcaaagt tttaaatcta ctatcaaata
     4501 aggtagaata atagaaaaag atggcaggag gaatgacgat gaatcatttt aaaggaaagc
     4561 aatttcagca ggatgtgatt attgtagccg tgggctacta tcttcgttat aaccttagct
     4621 atcgtgaagt tcaagaaatc ttatatgatc gtggcattaa cgtttctcat acgacgattt
     4681 atcgttgggt gcaagaatat ggcaaactac tctatcaaat ttggaaaaag aaaaataaaa
     4741 aatcctttta ttcatggaaa atggatgaaa cgtacatcaa aattaaagga aaatggcatt
     4801 atttgtatcg agccatcgat gcagatggtt taaccttgga tatttggtta cgtaaaaaac
     4861 gggacacaca agcagcctat gcttttctta agcggttagt gaagcagttt gatgaaccga
     4921 aggttgtagt cacagataaa gccccctcta ttacaagtgc ctttaagaaa ctaaaagaat
     4981 acggctttta tcaagggaca gaacatcgta ccattaaata cctgaataat ttgattgaac
     5041 aagactatcg tccagtaaag agacgcaata aattctatcg aagtttacgc actgcctcta
     5101 ccacgattaa aggcatggaa gccattcgag gattatataa gaaaacccga aaagaaggca
     5161 ctctcttcgg gttttcggtc tgtactgaaa tcaaggtatt attgggaatc ccagcttaaa
     5221 tcatagatac cgtaagggat tttattcttt atttaaaact ttgcaacaga accagcgaag
     5281 taataaagta agtacctggt ctaaaaacgg cattacagag cataaaggct atgacaaaaa
     5341 agttttatcc atgtataaga acgtattttt tgaaatgctt gagcgaatta ttcaattaga
     5401 aaacgaaaaa gaatagaatc acaaatcaca agtgattaat cacaaatcac ttgtgatttg
     5461 tgattgttga tgataaaata agagtaagaa gaaatagaaa gaagtgagtg attgtgggaa
     5521 atttaggcgc acaaaaagca aaacgaaatg atacaccaat cagtgcaaaa aaagatataa
     5581 tgggagataa gacggttcgt gttcgtgctg acttgcacca tatcataaaa atcgaaacag
     5641 caaagaatgg cggaaacgta aaagaagtta tggatcaagc cttagaagaa tatatacgga
     5701 aatatttacc tgacaaactt taaaaggagt gaaaatgaaa tggcagttac gtatgaaaaa
     5761 acatttgaaa tagagatcat taacgaatta tcggcaagcg tttataatcg agtattaaac
     5821 tatgttttga accatgaatt aaataaaaat gactctcaat tattggaagt caatttatta
     5881 aaccaattaa agcttgcaaa acgtgtaaat ctttttgatt attctttaga agaattacaa
     5941 gccgttcatg agtattggcg gtcaatgaat cgttactcaa aacaagtttt gaataaagag
     6001 aaagtggctt aatatggcaa atatagtcaa ttttactgac aaacaatttg agaatcgctt
     6061 aaatgataat ttagaagaat tgattcaagg aaaaaaagcg gttgaatcgc caaccgcttt
     6121 tttacttggt gggcaaccag ggtcagggaa aaccagtttg cgatcagcaa tttttgaaga
     6181 aacacaaggg aatgttattg tcattgataa tgataccttt aaacaacagc accctaattt
     6241 tgatgaacta gtgaaacttt atgaaaaaga cgtagtaaaa cacgttaccc cttattctaa
     6301 tcgcatgaca gaagcgatca taagccgttt gagcgatcaa gggtataatt tggtgatcga
     6361 aggtacagga cgaacaacag acgttcctat tcaaaccgca acaatgcttc aagccaaagg
     6421 ttatgaaaca aaaatgtatg tcatggcagt acctaaaatc aactcatatt taggaacaat
     6481 tgaacgatat gaaaccatgt atgcagatga tccaatgaca gccagggcaa caccaaaaca
     6541 agcgcatgat attgttgtca aaaacttacc gaccaattta gaaacccttc ataaaacggg
     6601 cttatttagc gatataaggc tatataacag agaaggagta aaactctatt caagtttgga
     6661 aacaccttct attagtccaa aagaaacctt agaaaaagaa ttgaatcgta aagtatcagg
     6721 gaaagaaatt caaccgactt tagaacgaat agagcaaaaa atggttctaa ataaacacca
     6781 agagacacct gaatttaaag caattcaaca aaaattggaa agcttgcagc cacctacacc
     6841 accaataccc aaaacaccta aacttccagg tatttaaacc ttaaaaaagg aaaagagtag
     6901 ttaccaaaaa acggtaacta ctcttttttt ataaaaacat ttcctcatgt tggggtcccg
     6961 agcgcctacg aggaatttgt atcgataaga aatagattta aaaatttcgc tgtttttttc
     7021 taatttcatt ttgaggtgaa ttaattggta gttattagag gtgccctata cctaataatt
     7081 tatctacatt ccctttagta acgtgtaact ttccaaattt acaaaagcga ctcatagaat
     7141 tatttcctcc cgttaaataa tagataacta ttaaaaatag acaatacttg ctcataagta
     7201 acggtactta aattgtttac tttggcgtgt ttcattgctt gatgaaactg atttttagta
     7261 aacagttgac gatattctcg attgacccat tttgaaacaa agtacgtata tagcttccaa
     7321 tatttatctg gaacatctgt ggtatggcgg gtaagtttta ttaagacact gtttactttt
     7381 ggtttaggat gaaagcattc cgctggcagc ttaagcaatt gctgaatcga gacttgagtg
     7441 tgcaagagca accctagtgt tcggtgaata tccaaggtac gcttgtagaa tccttcttca
     7501 acaatcagat agatgtcaga cgcacggctt tcaaaaacca cttttttaat aatttgtgtg
     7561 cttaaatggt aaggaatatt cccaacaatt ttatacctct gtttgttagg gaattgaaac
     7621 tgtagaatat cttggtgaat taaagtgaca cgagtattca gttttaattt ttctgacgat
     7681 aagttgaata gatgactgtc taattcaata gacgttacct gtttacttat tttagccagt
     7741 ttcgtcgtta aatgcccttt acctgttcca atttcgtaaa cggtatcggt ttcttttaaa
     7801 ttcaattgtt ttattatttg gttgagtact ttttcactcg ttaaaaagtt ttgagaatat
     7861 tttatatttt tgttcatgtt atcactcctg aagtgattac atctataaac aaatacagaa
     7921 gttaaacgat ttgtttgtaa ttttagttat ctgtttaaaa agtcataaga ttagtcactg
     7981 gtaggaatta atctaacgta tttatttatc tgcgtaatca ctgtttttag tctgtttcaa
     8041 aacagtagat gttttatcta cataacgcat ttggaatacc aacatgacga atccctcctt
     8101 cttaattaca aatttttagc atctaattta acttcaattc ctattataca aaattttaag
     8161 ataatgcact atcaacacac tcttaagttt gcttctaagt cttatttcca taactttagg
     8221 gttaaccata cgcaagacca atcactctcg gacaatactc atgattttaa tgataaaatc
     8281 catgttaaac ccatagataa gaaatacacc tgcaataacc gttacctgtt tgtgccaatt
     8341 taaaaatgca ccactttttt ataattaaaa cggttgaaaa ctgtaccact aataactcac
     8401 aatagagaga tgtcaccgtc aagttaaatg tacaaaataa cagcgaaatt tttaaatcta
     8461 tttcttatcg atacaaattc ctcgtaggcg ctcgggaccc ctatctagcg aacttttaga
     8521 aaagatataa aacatcagag tatggacagt tgcggatgta cttcagaaaa gattagatgt
     8581 ctaaaaagct tgtagttaaa gctttttaga catctaaatc taggtactaa aacaattcat
     8641 ccagtaaaat ataatatttt attttctccc aatcaggctt gatccccagt aagtcaaaaa
     8701 atagctcgac atactgttct tccccgatat cctccctgat cgaccggacg cagaaggcaa
     8761 tgtcatacca cttgtccgcc ctgccgcttc tcccaagatc aataaagcca cttactttgc
     8821 catctttcac aaagatgttg ctgtctccca ggtcgccgtg ggaaaagaca agttcctctt
     8881 cgggcttttc cgtctttaaa aaatcataca gctcgcgcgg atctttaaat ggagtgtctt
     8941 cttcccagtt ttcgcaatcc acatcggcca gatcgttatt cagtaagtaa tccaattcgg
     9001 ctaagcggct gtctaagcta ttcgtatagg gacaatccga tatgtcgatg gagtgaaaga
     9061 gcctgatgca ctccgcatac agctcgataa tcttttcagg gctttgttca tcttcatact
     9121 cttccgagca aaggacgcca tcggcctcac tcatgagcag attgctccag ccatcatgcc
     9181 gttcaaagtg caggaccttt ggaacaggca gctttccttc cagccatagc atcatgtcct
     9241 tttcccgttc cacatcatag gtggtccctt tataccggct gtccgtcatt tttaaatata
     9301 ggttttcatt ttctcccacc agcttatata ccttagcagg agacattcct tccgtatctt
     9361 ttacgcagcg gtatttttcg atcagttttt tcaattccgg tgatattctc attttagcca
     9421 tttattattt ccttcctctt ttctacagta tttaaagata ccccaagaag ctaattataa
     9481 caagacgaac tccaattcac tgttccttgc attctaaaac cttaaatacc agaaaacagc
     9541 tttttcaaag ttgttttcaa agttggcgta taacatagta tcgacggagc cgattttgaa
     9601 accacaatta tgatagaatt tacaagctat aaggttattg tcctgggttt caagcattag
     9661 tccatgcaag tttttatgct ttgcccattc tatagatata ttgataagcg cgctgcctat
     9721 gccttgcccc ctgaaatcct tacatacggc gatatcttct atataaaaga taacccgtgg
     9781 tgctagttaa ttttttccta gaggaaaatg tctaaacatg ttggtaaatc aacaaaaaaa
     9841 cgcatatagt agtctcaaaa ctcccaagaa atgaggacta catatgcgtt catcaaaata
     9901 tactgaacat tatacagata cttttataac attcaaggaa attatgagaa ctgtttctaa
     9961 catataccac aattgtgtac cagataagat taaaaaccga agaaatactg atcaactgaa
    10021 gcaacgcgat acagtgatta ttgcttgtgt tatatggggc ataattaatg gctatactag
    10081 ccaaagagcc acgtatagag cggtttgttc cgtcttattt cctaatggtg actttcctag
    10141 taggagtcga ttcactcgct taagttcaaa cttagcttac actatcaaga ttattcgata
    10201 ctttttcatc aagaagctca ccaaaggtga actagtcgga attatagata gttttcctag
    10261 tccattatgt aaaccagtta gaaatagaca agcaaaacta ttgaatcaaa tagccaaagt
    10321 tggctataac tcaacaaaaa aatcttattt ttatggtctt aaaattcata tgatcgttac
    10381 taagactggc tttccgatta cttactcaat cacgaatcca ggtgtccatg acgtgaaagt
    10441 gttagagact ttatcggaag aagcgaatct tcccaatatc ctaggggaca aaggatatat
    10501 tagccataaa atccatgaaa agcttgccct taagggcatt actatatccg ttcctccacg
    10561 taaaaacatg gataaatcag aaaaactaga ccacagctta cttggaaaac aaagaaaaac
    10621 agttgagact gttttttctt ccttagaaaa attaggttgt caaaatttca actcacgttc
    10681 tgttaaaggg ctagagagta gatttgaaag catattactg gcttacagtg ttctattaag
    10741 tcgagcacaa cgacgttttg gaggaacttt gagatattct ttaggatatt aaaattaact
    10801 agcaccacgg gttaaaagat atattatctt atcagtattg tcaatatatt caaggcaatc
    10861 tgcctcctca tcctcttcat cctcttcgtc ttggtagctt tttaaatatg gcgcttcata
    10921 gagtaattct gtaaaggtcc aattctcgtt ttcatacctc ggtataatct tacctatcac
    10981 ctcaaatggt tcgctgggtt tatcgatatc tttcaggtgc cctgctttca tttctgtaat
    11041 cactgttccc gcctctcttc tatatcagcg gcatatgtgc tatccaggca gccggtttta
    11101 ccagtgtatt ttttatacat gtccctggta tattttgtta tattcctatc atactccgga
    11161 taggcataat gaagcctttc cgccacctca ccggataccg ccctgaacaa ttgatggcat
    11221 agaaataatg cttcccatat gttttcatag gaatccatcc ggtaggtgga caaaagtttc
    11281 tcccacaaat cctcggatat atacctttca ataaacttat agttcttgcc tacacttaat
    11341 ttaaagcctg tttcgatgcc gaccttccat gatatcattc tcagcagctc atggcgaaca
    11401 atctgattaa aatgatcaat agcaaataaa atttccttac ggcacaatcc tttaataaca
    11461 taaggtgtta cattccaaaa ttcattgcag caatcatcat actcccttgc gcttggcttt
    11521 cttacatgat aatctatatc agtcggaact atgtcccttt taattctaca atctttatca
    11581 attagaacct ttattaattt atcgcccttt aggtaattat ctaactcttc caagggcaat
    11641 aaggtaagat caattttatt gtaatcatca aatagcataa gataggaaaa tcccttttct
    11701 tcaggtggga ataattccat atcctccggc ttttgcatca ttattatatt cccaaattga
    11761 ttaagccagt catcattaga tataaacggt tctatatcac ttacaaaata tgtaatatca
    11821 taatcctgaa attcatcttt aggtatatta atatttgcgc gtgacccctc aagggtcaca
    11881 attcgaatac gttcatcctg ttctgctaaa gaaagtacta aatccatcat ttctttttct
    11941 gatctcattt acatactcct cgtttatttt ttctatatta ttacatcttc ttttttgccg
    12001 atacaatcag catcattggg cgtcgcattt catccgccat ccccggaata tccatcatgt
    12061 tctctggcgg ctgtggctcc acaatctgat ttattataaa actatttgaa agcagtgtat
    12121 ttagatatgt ggtcagtgtt ctatgatatt ttgtaacctt ttcttccaaa aacatagctg
    12181 tccgtttgcc ctcataataa taattgtcca ccgggaaatg cagtatttct cctttttcgt
    12241 tataatacca gtcttgtgtt ccatgagcag taaaaacagg atgttcaact gtaaaaacta
    12301 aattgccacc agccttcagc atcctatata tcttttttat taaattctca tagtctgcta
    12361 cataatgaaa cgcaagcgaa cttagtatta catcaaagct ctcctctggg aaatccacat
    12421 cttctatggc acagcattca tattcaatct gtggaaaatg ggtttttcct tttgctactt
    12481 cgagcatttt atgagaaata tcaacaccta ctacagagga agcaccgttt tccatcgcat
    12541 atatacagtg ccatccatag ccgcatccta aatcaagcac acgcttaccc ttaaaatcag
    12601 gtagcatctt tttcaaagtc tcccattctc ccgcaccagc cagtcctttc tgcgagcgac
    12661 tcatttgact gtatttttga aaaaatatat tatcatcata tttgttttct ttcatctgaa
    12721 ctctcctcgt ttaaaaagtt atttatctcc gatacaattt cattcacttc tttataaagt
    12781 ttctcggtca tgtcgtagca ttcaaaaaga gaaagaccga gtacttcaaa aatatgatta
    12841 actctttcgg catatttttc aggtttatat tcaaaagttt caagcagttt tatagctttc
    12901 ttttcgttaa tgcaataagc attattacat gcaaatagta cttgatttaa gcatgaaata
    12961 atacgaaaaa catggcctgc aatataatat ttatcctctg cccccgcatt tgcttttaca
    13021 aacattaaag agaattcagc ttcaaatata aaaaagttca tcaagctttt ctttagagca
    13081 gtagggtaaa tttctgcctg cttttttaat tcgcataagc tttcgttctt agcatatagt
    13141 attttactaa tcgctaattc tccacgatac atagcactta tataaccatg gggatgcccg
    13201 gtctgataat tggcagtaac aattccttgc tccgtatctt tgattatttg ttccacccgt
    13261 tttatatcac gtaatatcaa gtcaacatga cacccgttta taactaacca tccaccgcca
    13321 ttaacccaat caccccacgc tccgggaggt acaacaaggt tgtttctatt ctcatcatcc
    13381 aactctgtag caatttgatt aatcgctgtc aggtcaaatg agtctgaatt gtaatagatt
    13441 ccgatatcta tatcagaatt ttctgtatgg gtgcttcttg cacgtgagcc ccctaataca
    13501 atgccttcta taaaaggcaa agatgataat ttctctgtta ctatttgaat aacattacct
    13561 accatataaa catcctcctt tattcgttag atatttttat ttcatctcca tctggtaaaa
    13621 taaatgcctg cacaaacttg acacctagca catcagcaat ggccttcaac tcatccaagg
    13681 ttactgtttc tcgttgtaat tttttattaa aattctgtgg agtctggcca atacgtctag
    13741 caagttcgga aacacttata ttcatttgct cacacagttc tttaatcatt tctgccgtag
    13801 tcatacagca cctccaagtt tatgctaaga ataacataaa ccatttggtt gataaatgca
    13861 atagtcatta aaatattatt ataatcagca attaaaagaa aacccacaac tctacttcag
    13921 agtcatgggc tatttacttc tggttttcat atttccattt cgatacctgg tttgaaggct
    13981 atgacgaagt ggtcttcata gaccttaacg ttctggatta tcttccttac aagcttatca
    14041 tcatattcta aggtgcggaa tttgttcttg cggataaatt caatcaactc attgatgcgc
    14101 tcgttctcgc cactgaggga ggcatcttct actaaaagag tctgacgctt atctcgcatc
    14161 tcatcgatct catctaccag gtattcataa tcttgacctt tattggccag cttgattagt
    14221 tctttttgtt tttcatctag tagggtatta atctctgaaa tttggtattc tgtggtttct
    14281 ccaatcacag catgaatatt ttcttccagt gtctttatca tattgttgcc accagcaagt
    14341 agcttattaa ttgcggtcat taccgcacca tagagttcat cttcttttac ggttcggttc
    14401 ttacatacct cgggaccctg ctcgattcta gtcacgcatc gccagacaaa ttcttttctg
    14461 ccatgaatat tccaataggt tctcctataa atatcgccac aatatccaca gaaggtgatg
    14521 gcacttaaag cgtacttgct actataaatt cttttgttct tgccttctcc tgtgtagata
    14581 ttacttctcc gataaatttc ttcttgagcc tgcaaaaata actctttaga aataatcgct
    14641 tcatggctat tttcaacata atactgggga aaatgagaga ttaactacag tctcacttac
    14701 tggctagtga cagtaagcag acacactcaa cgtttagtac tcaggcgatt tagggatcaa
    14761 gtcaacaaac actaaaaact attgattgca taggattttt aagcatctcc taacaaccca
    14821 acatctaatc tatcacttca tttaagtagg gtattttagt ttcgctgtta aaatcaagcc
    14881 tatttttatc tgtggatgta aatcctacta atatccgatt ctccactccc ttaagccatg
    14941 caaagaaatt ctaaaccata tttgcaccaa aaagagatta accactagcg gatcgaagaa
    15001 aaacaccttg tctcagctac gtcaaaagat gaaatgtgag tgacgctaga ttcgtgcttc
    15061 agcaattcta ggatcgaagc ggtctcgcag cccctcacac aaggcggttt tccataggat
    15121 agcgcgagat tcaatcacca ctatttgcca aagagcccaa aaaaccgcta gccaaaaatc
    15181 ggctaccggt tctaaaaatg atgtttatcc ttttcgagtc taacaactcg tcaggacgaa
    15241 caataattat tttcttgtta acagacatac tgcttccaca tggattgaga ggacagaatg
    15301 aatgtcattt gtgtatgtcc gttctcggaa acatatccac gacacttttt gcactatcgg
    15361 tagacgggaa catatccata ggcttcgctg ttttttgaaa aactgaggta tgctgttaat
    15421 tttcagtacc caatactgtg aataacgtta ctctcctatt cactaatgta attcaacaat
    15481 ctttctaaaa tgtcatgtgt aacttttaag ttgtattgtt caataaggtg actttgcaaa
    15541 tccataacta atagcaaaga atttttatag gcttcaaata attctacctt atctaatcga
    15601 gcagtggtct ttgcaaattt tttataattt tcaaggctaa tttctttttc aaggttttta
    15661 ctcatgttta gccaattatc agcatttttc tgccatacgt ataagttgta gtgtattttt
    15721 ttgaagttgt gataagagtt ctaatgaacg agcatattct cctcttttta gaacgttgat
    15781 tcccatcaac catagattag agaaattaca caacaaaaaa ttagcatttt cttcagtaag
    15841 tctatttggt cttgcaccac ttatctctga taaataattt tctaattgcc ctgtttcatc
    15901 gtaaataagc atagccttcg tatcaggaat ataacctgaa tctttaaacg aggggattat
    15961 gttcatatct ttttcagaaa ggaaatgaaa ttccccacgt ataagattat caaaaataac
    16021 tacctctgtt ccgtactcat ttttataaag catcaagtac ggagctacgt caaacaacca
    16081 gttggatgaa tcaaagttcg aggttatact atctttcaaa aatatataga actctatatc
    16141 agagtattgg tcaccttctc ctttggtaaa cgatccatac atcatacaag ctgtaattcg
    16201 ttcatctgac tcagtaagat tcttaacgtt tgcaattaat tctttttgtt ttaacatttc
    16261 ttcacccttt catgtaaata tcttttagtt attgtggcaa ctcaaaatct ctacaaacct
    16321 aaattaatat ttttcgtaca aatgttattg caaaaagcat catcatgctc cacaaacaat
    16381 agtgtaggac aatattccaa aatcattttt tcaatttgga tacgtgaaaa aatatcaata
    16441 tagttcaatg gctcatccca tatatacaaa tgtgcacttt cacaaaggct tttagcaatt
    16501 agtactttct ttttctgacc agcactaaaa tccaccatgt tcttatcaaa ctgctctcta
    16561 ttaaaatcca gtttacgaag aatcgtttta aatagagttt catcgatctt attattatag
    16621 gcaaattcag atagattacc ttttaaatat gaagtatctt gcgaaatata agaaattttt
    16681 agtccacttg ctagcataaa atttccggta aatttaatat catctccatt aatcaatttt
    16741 aggatactag acttaccact cccatttttt ccgataatgg caactctatc accaatattg
    16801 actctgaaat taagattact gcatacttct ttatctccat aagacaatga taaatcattc
    16861 gcttctatta agcactcttt gtgaaattca agtggtgaaa tttttaagtc atcatattgt
    16921 tcaatgttgt ggagcagttc tgatttttgt aaaacggctt cctgatgtct tgactcaata
    16981 tttttggcac gtttcatcgc ttttgcagcc ttatgtccaa cataaccctt atccagtttt
    17041 gaaccagaat ttgttgttcc atatttactt ttttctactt tatttgacca gtttgaacta
    17101 cgttttgctg cataagacaa ccttcctatt tctttaagga gtttcttgtt ttctgccagt
    17161 tcaaaattat cttgtaacgt tttgttctcc caccaagaag taaaatttcc cttttggatt
    17221 tcgatattcg ttttattgat agatagtata tggtcaacac attgatcaag taagcttcta
    17281 tcatgagata ccaaaataaa ccccttcttg cgtttcaaat agttttgcac tacattacgt
    17341 gcatcgatgt caagatggtt tgtaggttca tcaataagca ggaaacaact cgctgtaagg
    17401 aataaagctg caagaaggac cttcgtttgc tcaccatttg acaatgtatt aaacggacga
    17461 tataaagcat cttcttgaac atcaagcaat gatatttcac gaaaaatctc ccaatccata
    17521 aattccgtac aaatactctt cattacttca attgtatata gactcttatc ttccacatca
    17581 taaggaaaat actcaaactt aactgtagaa cttatattgc cggaatacgc atatttgcca
    17641 agcagtaaat ttaagaaagt agttttaccg cgtccgtttc ttccaataaa accgagtttc
    17701 caatctgtat ctatctgaaa acttacattt tcaaaaatat tgtcataact tccttcatat
    17761 gaaaaagtta gatttgaaac atttattaag gacatatatt tcttcctcct ttacattata
    17821 aaaattttat aagcaaagtc ggttttcggc attaattact ctataatgtt atccaactct
    17881 gcaaggattt tgtcatgaat gacatagtat cattgtctat cacgtttatc ttcctttctt
    17941 ttacaaatat taaaagccgc aagaaagtaa attcttacgg ctcaaaaaca aatactatta
    18001 ttaccttttg ttatacataa cataaggtta ctgtaatgta ttattgagtg tagaatactt
    18061 aactttcttg caatttgcat aacaaaacaa acggttctat agccgtttct ttaaatatct
    18121 tattatgcat catataatta gcaagaaaag ttatacattc ttccacctcc aagtcgtttt
    18181 attatatcat attatcttta aaaatccaat ataattcttc tgttctcttt ctaaagatta
    18241 cccttctaca tcaatctcga ctcctgattt gaattcaacg gcgaacttat catgaaatac
    18301 cgtaactttt tctataagcc tccttactaa ctgctcatca tattcctcta actcacagga
    18361 ttgttcatta aagaaatcag tcatttcagc gattcgttgc ctttttcctt cacgctctgc
    18421 attttcaaca agtgcatttt gcttcaattc tcgaaggtgg tagatttcat cagccacatc
    18481 ttcatagtca ttcttggatt ttgcttggat aagaagctgt tgttgtaatt cttccaattt
    18541 gctatcaata tcattggtgg cattatcatt ttcttcatta agtatagtag ctatgttttt
    18601 ctgcaacgcc tggaggaagg gttctttgtt agccaaaagt tcgttaatag ccttgacggt
    18661 tctgttgcaa agttttaaat aaagaataaa atcccttacg gtatctatga tttaagctgg
    18721 gattcccaat aataccttga tttcagtaca gaccgaaaac ccgaagagag tgccttcttt
    18781 tcgggttttc ttatataatc ctcgaatggc ttccatgcct ttaatcgtgg tagaggcagt
    18841 gcgtaaactt cgatagaatt tattgcgtct ctttactgga cgatggtctt gttcaatcaa
    18901 attattcagg tatttaatgg tacgatgttc tgtcccttga taaaagccgt attcttttag
    18961 tttcttaaag gcacttgtaa tagagggggc tttatctgtg actacaacct tcggttcatc
    19021 aaactgcttc actaaccgct taagaaaagc ataggctgct tgtgtgtccc gttttttacg
    19081 taaccaaata tccaaggtta aaccatctgc atcgatggct cgatacagat aatgccaacg
    19141 tcccttaatt ttgatgtacg tttcatccat tttccatgaa taaaaggatt tttaattttc
    19201 tttttccaaa tttgatagag tagtttgcca tattcttgca cccaacgata aatcgtcgta
    19261 tgagaaacgt taatgccacg atcatataag atttcttgaa cttcacgata gctaaggtta
    19321 taacgaagat agtagcccac ggctacaata atcacatcct gctgaaattg ctttccttta
    19381 aaatgattca tcgtcattcc tcctgctatc tttttctatt attctacctt atttgatagt
    19441 agatttaaaa ctttgcaaca gaaccctaaa aacactatat attccgaaaa gtgagtatct
    19501 ccattcataa aataatcaac atatgtgaac tactcaccac ttagctaaac ctgacggttc
    19561 ttaacgcttg aagtgggagc ttcttgggaa tagagcatac ttgatagcgt atttctttac
    19621 taacagcggt gtctcttatt taccaagcta tccccgtagt tcctacggtt cttgatgatt
    19681 ggatctaagc caatcccata gaatgtagtc ttagaccttc ggtcagaata ttgatactag
    19741 cattgatatc acgatcatga tgagtatgac aaacaggaca agtccattct cgaatttcaa
    19801 gagatttctt gccatcttta tgtccgcact ctgaacaaat ctgactagac ggaaaccatt
    19861 tatctacttt gatgattttt cgtccatacc agtcagcctt gtattgtaat ttagtcacaa
    19921 actttgacca agaaacatca gaaatacttt tagctaattt atgatttcgc aacatacctt
    19981 ttgtgtttaa gtcttcaata cagataatat cgtgattttt gatcatttct gtactcaact
    20041 tattcagaaa atcagtacgt tgattcatta ctttttcatg caatctagct actttgcgtt
    20101 tttgtttttg ataattttta gcttcaaata gattggtacc tttattttta gccaataaag
    20161 cacgcctaga caatttgcgt tgttcacgct ttagtttctt ttccattttg gacgtgaatt
    20221 tattattatc aattttttgt ccatcagaaa gaatcgcaaa gtccataata cctaagtcaa
    20281 taccaattgt ggaattagtt ttaggtaatt cgataatttc ttctttacac aacaaagaaa
    20341 tatagtattt accgctagaa tgacgtgata ttgtagcgga tttgataatc ccttttggtt
    20401 gtctatgaag cttaattctt actaatgact tcaatttagg aactttgatg aatttactat
    20461 caatcaaagc aactgtacca ttttgattat tcgttgtata actctgaaca ggatttttct
    20521 tacttttgaa acgtggaaat ccaacggatt tatcccgaaa aaaattcttg tatgctttat
    20581 ctaaattaag ttgggcattg gctaaagcaa ggctatcaat ttctttcaaa aacggaaatt
    20641 ctttcttgta tttagctggt gtcggaaaag tcattttttt agaagaatca tttttaactt
    20701 cttcatacgc cttttttcgg tcatcaagca ttagattgta gaccttacgg acacaaccaa
    20761 aagatttggc aaagaagatt tcttgttcct ctgttggata gattctgaat ttgtatgctt
    20821 ttagttgttc cataaagttc acctactttc tatttatgat tgtttccttg attttggata
    20881 tacttcttaa tcacatcaat tggtgcgcca ccagttgtca gaagacaaaa acttttagac
    20941 cagaacattt ctttccaaag aaattgtttg actcttggaa agtcacgttt tatcaatctt
    21001 gagctggcac ttttataggc attgatgaat tttgtcaatt ctgttttagg ttgagctttg
    21061 aacataatat gaacgtggtc tttatcatga ttccactcca ctaaagtaat gtgatacgat
    21121 tctgaaattc tttcaaaagt agttttggca taatcagata tttcatcatc aatcacttgt
    21181 ctacgatatt tcgttactaa aacaaggtgg taataaagaa gaaatactga atgattattt
    21241 gtatctaatt ccatgttata tcaactcatt tcttgtatag actgattgta acatggaaca
    21301 aaataaaaag gcaatacgcc ttagttgtcg gtcttcgagt taccaacggt aaccctcata
    21361 ccgaacggca ttcatcaccc acctatagag gatgggcgac ttctgcctaa ttctgttaaa
    21421 aaatctaatt agctttttta gtcaatctaa agttctttat tctatgatat aatgttactg
    21481 tagaaagttt gtggcggttt ggcaaatcca attgaaggag cgtggtgcct atgggcttat
    21541 tagcttatcg gacgtactct gtagaaagga aatgcctgat ttgttctcat tggatcaaat
    21601 cattgctatt atcggagcag cagcagtagt tattactgcc gtagcgaaag ctagcgattc
    21661 gattttagct tggttaaagt tcaaaaaaga acaaaaaaaa tagagccgtc tcaacttttg
    21721 gcgaggtaga cgagctctaa agctttattt acatgccatc cgctttgaac ggactacact
    21781 gggcatgtga cagcatgccc tttcatttat attatatctc attcttttat ataatgaaag
    21841 taaataaatc atggaggata aaatatggat aaatttaata gattaacatt aataaatcag
    21901 tttgaaattt taaaagcttt aaatcctaac gaagaaaaat actatgctga aaaaatagaa
    21961 atactaacag aaggttacga atatcactat agtgaaatat ttgaaaatat ttctgatcca
    22021 ttgccagaag aagattcgcg gtttgttcta gacatattaa atatgtatag agatattact
    22081 tttagtaaaa ataaattaaa agatataaat tcaattgata attattatat acaatttaaa
    22141 ggttttgact ttaatagctc taccgaattt aagttagcac tttatgcaca attttttatt
    22201 gaaaaattaa ataggtttca agaaatagtt gaagatagtg attttaacac ttttaatagc
    22261 cataaaccga tgagaggtac ttatataaaa tttctcgaaa attataatga tttaaaatct
    22321 accaataatt atcaatttgg aaacttgtct tatgagatga taagtaaagt tctaagtttg
    22381 tgatgataaa tgaaattaaa tagtataaat gatttatttg ctattatagg tgttattgct
    22441 aacatacttt tttcgtgttt gaattttaga tttactcaaa agaacaaaaa gaacaaactc
    22501 agtatagaac aaatgaaaaa agacattgaa actgatttaa aaaatgacca taaagaaaga
    22561 agaaaaattg aagaatatac ttctttaatg gaaaagtgta aagcaactga tgcaattttt
    22621 agctttttaa gaaaaagtga tgagataatc acacgtgaaa atatagattt agaaaatgag
    22681 attagtaaac ttgaatctat cttttccgat ataaattctc ttaagtattt aatcgtcgaa
    22741 gaaaattcgg atagcttttt agaatttgaa aaatatctaa cagatcttat agataataga
    22801 aataatgaat taatgagaca aaacattgca agattcctta ctaaattagt ttctgaatgg
    22861 aaaagtatta tttctcaaaa tatggataaa ttaagatatt aaggatgtta gttttaaaat
    22921 aaactaatgt ccttattttt gtgttcacat ttctgttacc taagaaatac ttaaaggagg
    22981 tgatgtagcc agcaacgact acaacttgaa cccgctatct acagtttatt tgttgtttct
    23041 tttgggtata ctctaatggt acaaatccat atttgcttaa agcgttgatt tttcagcggt
    23101 ttttctttat tgcaaagtgt accctaagac ctgtatacta atagtaaata gattggatag
    23161 gaatgatggc aaatgtattt agcttattta agagtttctt ccgacgatca aagtttagct
    23221 cggcaacata agctaattga aaattggtca gtcaaaaata atattgctga agacgattta
    23281 aaaattttcg aggaaaaagt ctctggaaaa aatattgaaa acagaccaga gctgcaagag
    23341 cttatttctt tcatacgtga acgagatacg attattattc ctagtcttga tcgattagca
    23401 agaaatagta aagatacaaa agacttactt caattgtttc gtagtaaagg tgcttctatt
    23461 gaaatattag acctaccgtc gtttaatggg gtaactgacc ctgcattaag agacttgcta
    23521 acaaatttag tcatagaagt gtttagctat gttgctgaaa acgaacggaa aaaaatcaaa
    23581 gagcgtcaaa aacaaggcat tgaaattgca aagaaaaatg gtcgttatac tggtaaaaag
    23641 attcaatacc atgccaatgc aacaggaaaa aacaaattga tttacgatga aattgttgat
    23701 ggtctgaaga aaaaagaaac tatttctaaa atagcaaaga acgcaggagt tacaagaaaa
    23761 accgtttatc gagtaaaaag agatttagga atgtaatatg ttccagttag aaagaagggt
    23821 tctgttgcaa agttttaaat ctactatcaa ataaggtaga ataatagaaa aagatagcag
    23881 gaggaatgac gatgaatcat tttaaaggaa agcaatttca gcaggatgtg attattgtag
    23941 ccgtgggcta ctatcttcgt tataacctta gctatcgtga agttcaagaa atcttatatg
    24001 atcgtggcat taacgtttct catacgacga tttatcgttg ggtgcaagaa tatggcaaac
    24061 tactctatca aatttggaaa aagaaaaata aaaaatcctt ttattcatgg aaaatggatg
    24121 aaacgtacat caaaattaaa ggaaaatggc attatttgta tcgagccatc gatgcagatg
    24181 gtttaacctt ggatatttgg ttacgtaaaa aacgggacac acaagcagcc tatgcttttc
    24241 ttaagcggtt agtgaagcag tttgatgaac cgaaggttgt agtcacagat aaagccccct
    24301 ctattacaag tgcctttaag aaactaaaag aatacggctt ttatcaaggg acagaacatc
    24361 gtaccattaa atacctgaat aatttgattg aacaagacca tcgtccagta aagagacgca
    24421 ataaattcta tcgaagttta cgcactgcct ctaccacgat taaaggcatg gaagccattc
    24481 gaggattata taagaaaacc cgaaaagaag gcactctctt cgggttttcg gtctgtactg
    24541 aaatcaaggt attattggga atcccagctt aaatcataga taccgtaagg gattttattc
    24601 tttatttaaa actttgcaac agaaccaact agactgtgca aaatagagac acttgaaaaa
    24661 tctatcgggg gtcagaaact taatagtttt tgacacataa acaaaatcgc gatataatgg
    24721 ggttgagagt gtttcataaa cttatgtcat aaagttaagg agatttcgca tgattttaga
    24781 gaataaattg ggattaacca atcaagttga gttggctaag gttgaagaaa aactcagtaa
    24841 acaaaaagcg aaagaattgt acgattgtgg aaaaataaat gaaatcgaag ttggtacatt
    24901 taaaggttta tctgaaattc atgaatttct attttcggat atttacgatt ttgccggaaa
    24961 aatccgatcg gtcaatattg caaaaggaaa ttttcgattt gcaccagtta tgtatttaga
    25021 acattcgtta cagcatattg atcagatgcc acaaacttct tttgaagaga ttatcaagaa
    25081 atatgtggag atgaatatcg ctcacccatt tcgagaagga aatggccgaa gtactagaat
    25141 ttggctggat ctcattttaa aggaagaatt gcaaaaagtt gtagattgga acttaatcga
    25201 taaagcagac tatctttctg caatggagcg aagtcccata aacgatttgg aaatacgcta
    25261 tctaatttcc aatgctctga ctgataaaat tgacgatcgc gagttatata tgaaaggaat
    25321 cgatgtcagc tatttctatg aagggtattc tgagtatacg atagatgatt tgtaaaagta
    25381 ggtggaccaa atgacgaaat atggatatgc acgtgtctca accgcttctc aaagtacaaa
    25441 agaacaaatt caacagttgc ttgagaactg cgtagagaag aagaatattt tttcagaaaa
    25501 atttacgggt acaaaacggg atcggccaaa attcaatcag ctgttggctg gtctgaagcc
    25561 tggagatgaa atagttgtta cgaagcttga tcgatttgct cgtaacacga gagaagcatt
    25621 agagatcatt gaacctttac tcgatgataa cgtaacgatc aaggttttga atctaggaac
    25681 gattgaaaat acgtccatgg ggcgaatggt gacacggacg ttgttgagtg tagcagaaat
    25741 ggaacgtgat atgattgtgg aacgtaccca agaaggaaaa atgtttgcaa gaaagaataa
    25801 tcctaatttc agagaaggac gtccgaaagc aacaatcaca ccgaagaaga ggcacgcata
    25861 tgaactgctt acttcaggta aatcgtataa ggaagttgaa gctataaccg gtttcagtcg
    25921 cagtacgctt tttagaataa agaagaaaat tgaagaaagt taaaaaagaa gtctcagcga
    25981 accagacagg taaatactta atgcgttcta gatatgagtc tattagcatg ttgtgaaata
    26041 taatattttt ttatttactt gatttctgct caaaaaatgt gtatggtaac tgtaaaaggt
    26101 aaagtaatta aaggtatgct agccacgctt actatattag gataccatca tatatttata
    26161 atgaacgatt tgttcgtcta ccaaacaaca catatcgttc agcgtaagtc acgtttagga
    26221 acgtggcttt tttagtgtta ttatcgataa ataatctatt gactctattg attttatctc
    26281 catatcccta cggtgttgat tgtctttaga tctttcattt aagaaccaaa taactatcat
    26341 aaaaatcagc actgctgcta atataataaa cagcattcct attgtgatat tactggattt
    26401 gagtcaatat cttggacaca ttttagtaga gacggttaag ccattttttc ttttgctaat
    26461 tcttcaaatt cctgtggggt tagatagtga atcgagctat ggattcgatt tcggttataa
    26521 aatccttcaa tgtagctaaa tagcgctcga tttgcttctt caaaatctga gtagctagtc
    26581 gtgtagactt cttctttttt caatgaggca tggaaagatt cgattccagc attatcataa
    26641 ggtgttcctt ttctactata agaatgcctt attttgttgg ttttaagcca ttgttccact
    26701 tctcttgctg tgtattggct gcccaagtca gtgtgtagaa tcattccttc tggaatgtga
    26761 taatgtattt ttgctttatt caatgtttga atgacacaat ccacagtcat tcgttttgaa
    26821 aatgtataac taataattct tttcgtgtgt aaatccatga ttgaagataa gtaacaccaa
    26881 ccatttttct tagtaggaat gtacgtaatg tcagctgccc atttctcaca gatcgtttca
    26941 gtagaaaagt cctgatttaa gagattctct tttgaaatga tggaatggca acagtttttt
    27001 tgacaaattt tataaggtgc agaacttctt tccgtatgct attccgattg tccttgacaa
    27061 tgagcctcct cggatgtgac gatcttcggc aggagctaac agttaaagtt agactgcctc
    27121 gctagcgtta gcacatccga gctcattatc aaggattcgc tgcgccaatc tctggttacg
    27181 gtaaccaacc ggtgtctcgt agccaagtgt accgtgcaac cgaaggtggt tccaccaatt
    27241 gacatagtca aataactcca aatccaattg ttgtaaggtt tcaaatgtgt attgatagac
    27301 aaattctact ttcaacgact tataagttga ttcagctacg gcattatcaa aaggacagcc
    27361 tttatgactc aatgatcgat tgatgtcaaa agttgttaat aattcatcaa tagcttggtt
    27421 atcaaactct tttccacgat cagtatgaaa aatctcaacc tctgtcagag gttgtttgat
    27481 acggctaaat gcttttttta ctagaacggc atctttatgt tctccacaag aatagccgag
    27541 aatttctcga ttgaacagat ccaaaatgaa acagacataa ttccattttt tcccgactcg
    27601 tacataagtc aagtctgtta cgatcgcttc taatgggttg tctcttaaga atttacgatt
    27661 caatacgttt gtcgttttgg cttcattgca agtagaatga tgtactttaa aataagcaac
    27721 agtatagctc gattttaatc ctctattttt catgattcta ctaatttttc gtcggctgat
    27781 ctgaatgcct cgttttgata aggctttttt tatttttctt gagccgtagg cctttcggct
    27841 gcggataaat tcttcagcga ctacttcttc aagttctgat tcgtctttct ttggttttga
    27901 ttgataataa taggactgac gtgatagacc taatattctg cacatcgctg atatagggta
    27961 aagatgctta ttcgcatcga ttacttgtct cttcgtccga atatcagcgc tgcttgcttt
    28021 aaaatatcat tttccatttc taattgctgg tttcttttac gtagttctaa caattctttt
    28081 tgttcaggcg taagattatc tttttctttg aatgaaccac tcgttttaga ttgctttacc
    28141 catttgtcaa atgctgaagc cgttagttca tattctcgaa tgatttctac acgtggcttt
    28201 ccagctaagt aaagattgac gatttgttgc ttgaattctt gtgaaaaagt tcttcgtgtt
    28261 ctcttagaca taaaaattcc tcctggtatg ttttcttcta gtctacacac cttaattttt
    28321 ctgtctagtt aattgtagcc tatccatgat cggtttatta gacctttgag gtctatattt
    28381 tttaactaca atcgacctta aatttaattg tttcattagc ttttggacat gtttaagaga
    28441 tactgaaatc ccttctttta ataaaacttg atggatcttt gtggcaccat agcgttgttt
    28501 attcgtaaaa aaaattgttg aaatcttctt tttcaactta ttatttctga tttctgtagc
    28561 tgtcaacggt ttattcttat aaaaataata gacacttcta gggatttcta ataaccgaca
    28621 caacaaagaa acagtgtaat ccttacacca tttttcaata aattgaacaa gcgaatttag
    28681 gttttccgag agaatatggc tgcggctttt tttaagattt caagttcctc atttaaacga
    28741 gcattttctt ttctcagttc agctacttct tttccagtca gtcctgtgga ctgatcaggt
    28801 aaatataaat tcttccattt gtaaatcgtt gcttcagata agccatattc tttcgctaac
    28861 cctcgaacag aacgtccagt ttgattcagt tcaacaatca tttgtttaaa attttcttca
    28921 tatcgggtca taaaaattca tcctctcgta gataagttta atttattctt gtctctacga
    28981 aaagctgtct aagatttgat actaacacca aatgttgtat acccccaaac aatacacata
    29041 ttttgaagga ttaggattaa taaagctaaa aatatagtaa gtatactaaa tatatttact
    29101 atatctagta tacttactat attttaatct tttgatcgtc tattatatat aatccgttcc
    29161 tcgtcgttta aagtatcaac ataggcgtcc attgcaagtt tgactatttc atacatagga
    29221 atatcttttg cataactaag atcccgaatg gtttttagta cgggaggatc tacttgaact
    29281 ggttttcttt ctttcgcagt gtactttcgt tcccctaact cgacattaat atcatcttta
    29341 attgaaatat cttcagcacc aattttcttc ttatctttgt tcgttggtaa taatgccatt
    29401 tagtttaatc tcctttccaa gaggtaggat atgattggcc attgagtcag catatttagg
    29461 tgtataatca aatccttcaa tatcaccatg ttgttcatag tattcaattc tttcttctaa
    29521 ttctgtaaag atgtctgcaa aaatagccca ccatcttcga tctacataat catttaattg
    29581 gataccattc tcaccataca tttctaaccg atccgagcct ttaacaatgc ttttaaaaat
    29641 gtttgattca ccatacttat caattgtttt ttgatagttt gcgtgttgag aggaacgtcg
    29701 cactgagaaa agaacaggca aaattccaat gatttgaaga tgagactctt caaaattcgt
    29761 gacaatcgga actaaaactt tattaataaa atcttctgtt ccttccattg cgtaccgttt
    29821 taattcttgc attgcaataa tataatctgc agcagttaag aatgcacgaa ccacattatc
    29881 tgttgatggt gggcagtcga taaagatata atcgaaattt tttctcaatt cttctaaagg
    29941 tttaatgaag gccaatgatc tcttacgacg atcaggatat ttttcggaca agtattcatt
    30001 aagttcttca gatccaggag agccagccat aatatataaa tgtggactta cttgagtaat
    30061 acctgaaacc cagtcccctt ttttgattgc tgcagacatg gatcgatcaa agctagtaat
    30121 ttgatacgtt gatccaatgt tggaagtagt atttctttgt tggtcataat caattagcaa
    30181 cacgtctttt tcaaaaagtt gactagaaac aatcgctaat aaatcattgt ctgtagtctt
    30241 accaatgccg ccttttctac ctgtaagcat tacaactttt cctagtttat ctgatgtttt
    30301 aaatgcagtc cgtaagtttt ccatagttcc ctccaatttc ctatactaaa tatatttagt
    30361 atacttcata tacttaatat attcgatata tctaatatac tccaaattga taagaattca
    30421 gactttataa ggaatatagt ggatatacta aatatatttg ctatattcag tatatcagat
    30481 atattcaaaa tgtcaaaata tatttgtgcg ttttgcgttg acaatttaga gtgaaaagag
    30541 gtaaacttaa ttctatagaa accacagata attcactatt tacaaagtag caaaagcagt
    30601 ggtactcttt aaacagaaaa attacataaa aaaaagagac ggaaataatt gattttagca
    30661 gaatcaatta tttctgaatc acatggttag gacatgtgtt cacgctcgtc tcaagaatat
    30721 gtaagtagct accaactact tatattaaaa gttgatcgga taccttttcc gattgccttt
    30781 attctaccaa aaaaaggcga gcaactcaac agaagaacgt ttatttagtg tacttaaatt
    30841 aaatattctt aaacactgaa gagagaacac atactatggc tgagattaaa gctaaactgt
    30901 gttctctttt tgtttgagaa aggacgttac aatcgatgtt gagcgaaatt tattcagcta
    30961 ttcttaaaaa cggcttacgt acatacaaat atcgaaacag cacc
//
