LOCUS       AP024493                9837 bp    DNA     circular BCT 22-FEB-2024
DEFINITION  Providencia vermicola strain N3 plasmid pPRVEN3-3 DNA, complete
            genome.
ACCESSION   AP024493
VERSION     AP024493.1
DBLINK      BioProject: PRJDB11239
            BioSample: SAMD00281820
            Sequence Read Archive: DRR274671, DRR274672
KEYWORDS    .
SOURCE      Providencia vermicola
  ORGANISM  Providencia vermicola
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Morganellaceae; Providencia.
REFERENCE   1
  AUTHORS   Sekizuka,T., Haque,A., Matsumoto,T., Sah,R. and Kuroda,M.
  TITLE     complete genome sequences of blaNDM-1 and blaOXA-181 co-harboring
            pan-drug resistant Providencia vermicola str. N3
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9837)
  AUTHORS   Sekizuka,T., Haque,A., Matsumoto,T., Sah,R. and Kuroda,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-FEB-2021) Contact:Tsuyoshi Sekizuka National Institute
            of Infectious Diseases, Pathogen Genomics Center; 1-23-1 Toyama,
            Shinjuku-ku, Tokyo 162-8640, Japan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method :: Canu v. 1.4; minimap v. 0.2-r124; racon v. 1.1.0;
            circlator v. 1.5.3; Pilon v. 1.18; SPAdes v. 3.11.1; A5-miseq v.
            20140604
            Genome Coverage       :: 342x
            Sequencing Technology :: PacBio RS II; NextSeq500
            ##Genome-Assembly-Data-END##
            Annotated by DFAST v.1.2.3 (https://dfast.nig.ac.jp).
FEATURES             Location/Qualifiers
     source          1..9837
                     /organism="Providencia vermicola"
                     /mol_type="genomic DNA"
                     /strain="N3"
                     /host="Homo sapiens"
                     /db_xref="taxon:333965"
                     /plasmid="pPRVEN3-3"
                     /geo_loc_name="Nepal"
                     /collection_date="2015"
     gene            101..622
                     /locus_tag="PRVEN3_P3010"
     CDS             101..622
                     /locus_tag="PRVEN3_P3010"
                     /inference="COORDINATES: ab initio
                     prediction:Prodigal:2.6.3"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="BCT08347.1"
                     /translation="MSKFKCSVLALTVLALSGCGEKSDIENAINKNIENKEYCYSLQDN
                     DISFPITIGRDNFSQDFSPILKGLANQGLVTLHNQGYRDYVISLTEKGAKTDFWDKKRG
                     VCMGKRVVDDIKEWTEGEQNTIMVTYTEKLVDVPRWVDKKSFSDIEGMDSPAEKRAVLK
                     KTSNGWKVWN"
                     /name="hypothetical protein"
     gene            794..1324
                     /locus_tag="PRVEN3_P3020"
     CDS             794..1324
                     /locus_tag="PRVEN3_P3020"
                     /inference="COORDINATES: ab initio
                     prediction:Prodigal:2.6.3"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="BCT08348.1"
                     /translation="MNYNLPSPEEMIKQLGDLINKRNEKERLGDFFNNDYFSEIRKCIN
                     NEVSEIKNMEVKRSIKGAYLSACIKRYKRNIVKDYILKIAIIEGLDLTQRIADLFFIEC
                     LGRSVGEFFLNEHFSGLQYKENKLTKIKRTSENIVLNPVKKEEVKGIIAKYKNQIIDSV
                     EKIKCYFYEAKLS"
                     /name="hypothetical protein"
     gene            1608..1967
                     /locus_tag="PRVEN3_P3030"
     CDS             1608..1967
                     /locus_tag="PRVEN3_P3030"
                     /inference="COORDINATES: ab initio
                     prediction:Prodigal:2.6.3"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="BCT08349.1"
                     /translation="MEVKKFYKDRYQRKNSVRLCFNDLEFSIVEQIAKDKRKSKATALR
                     EFILDKEIKIKKDIQLTDQSGVYYELHKIGVNINQIAKKMNTDLEQFLSGNGEEFAYLI
                     EEIFEYIEYIKNRIN"
                     /name="hypothetical protein"
     gene            1970..3388
                     /locus_tag="PRVEN3_P3040"
     CDS             1970..3388
                     /locus_tag="PRVEN3_P3040"
                     /inference="COORDINATES: ab initio
                     prediction:Prodigal:2.6.3"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="BCT08350.1"
                     /translation="MYHKIIGGIADRKQRNIKNAVNYLLRISKPEEQIHVKTLSMTSQQ
                     DLLNFNNFILPKNKKSPYVCGVLSFEEENINEDLKVKIMSDFEEMLFSGIELTNRPPLM
                     WVQHTDKDRLELNYLTFNALADGRSFTAYFDKTDRKLFNTFSEIINYENDFSSPLEKLD
                     KRNTLINKPNPQVPKDKKLLIENLNNEIMGKIMIGELVDRNEVIKYIESIGYKINRVRK
                     NAISIKLENDDKPIVLKGDIYEEGRIYADYRREPEVSNRRDPEVVKSALNQFRDDFERL
                     LSKRQDKHRKRFKSSQRSIEKSIESRVNSQDLDQNFEFQNSFGIGGVTFSKSNLYHDIN
                     HNNNFKIEEENSELYIRTNKRKEKTEAERFELLRNRILEAKRVQKSIDHGIERFRDQQH
                     RIRDSIRTTQFRNGFVRGYVARFSELFNEILRRAFSFSLRAKTLEERKEKAKILQKEKA
                     SELKSSGRKFRVRY"
                     /name="hypothetical protein"
     gene            complement(3556..4467)
                     /locus_tag="PRVEN3_P3050"
     CDS             complement(3556..4467)
                     /locus_tag="PRVEN3_P3050"
                     /inference="COORDINATES: ab initio
                     prediction:Prodigal:2.6.3"
                     /inference="similar to AA sequence:RefSeq:WP_002679305.1"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="BCT08351.1"
                     /translation="MLHKFNLKIDNESLDSKLLNKDINNYNSLIYNYGQDNLIKEIKSI
                     LDIDEEKKEVKIKHTDIIKNWFPESDCHIFMSHSHKDKNIAIKIANYLYANYKIKTFID
                     SYFWQFVDNAIYEINVNYSKNPKPNDHLLRYDSSLRVGTNFYLTLSNALMDTIDKSDCC
                     IFLNTENSISNINSESESTYSPWIYTELNILDKIRKNPHKDRGIRVGNESLVEKTAALS
                     AKTINESYKFDVEYEVNPSFRLPTISENIIEKILTSPNEIIEDYEEKELKYSNDKIILK
                     VKTISYLDDIYDFINSNLKIEK"
                     /name="hypothetical protein"
     gene            complement(4479..4913)
                     /locus_tag="PRVEN3_P3060"
     CDS             complement(4479..4913)
                     /locus_tag="PRVEN3_P3060"
                     /inference="COORDINATES: ab initio
                     prediction:Prodigal:2.6.3"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="BCT08352.1"
                     /translation="MDKNESIISSLGYIQDIIKRMASNSFFIKGWALSISAVIIALIPK
                     LDEIESYSPNSIPIVITLSIIILFMFSLLDTYYLQQERIFRNEYNRKVESIDNEDIKNS
                     LTIISLKKVKTSYLSVYFTISIIPYYFIMISSLIIGSYLI"
                     /name="hypothetical protein"
     gene            complement(4924..5190)
                     /locus_tag="PRVEN3_P3070"
     CDS             complement(4924..5190)
                     /locus_tag="PRVEN3_P3070"
                     /inference="COORDINATES: ab initio
                     prediction:Prodigal:2.6.3"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="BCT08353.1"
                     /translation="MKIKNQKRNTKAKDLAFEYGVSIATVKKYYSQDREDYEQEAAARR
                     KQAFELRQKGLAWREVADSMNATIDAVKSLAKRYKQQDLNLIG"
                     /name="hypothetical protein"
     gene            complement(5187..6041)
                     /locus_tag="PRVEN3_P3080"
     CDS             complement(5187..6041)
                     /locus_tag="PRVEN3_P3080"
                     /inference="COORDINATES: ab initio
                     prediction:Prodigal:2.6.3"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="BCT08354.1"
                     /translation="MYNDNQETIISQLPNKPYCSDNLDYGLKIRPKNKALDMLYLQINN
                     PSIQTCLLFDIDRDNSFYDFEEAHLPVPHFTTQNPENGRCHMGYILKRGVCKTQNAKLE
                     PLRYAAAVELEMGKSLKADQGFAGLITKNPFNPHWRPHWSNADLYELDYLADFITLENT
                     NKETTKYESFGLGRNVNLFDDLRHYAYKNVLKFKDVSDFHHWMNEIEKQAINLNTYSNP
                     TNLLPFNEIKATARSVGKWVWKNFSSEQFSKIQSERGKRNLGKTKTKKKAANLLAALRN
                     ELL"
                     /name="hypothetical protein"
     gene            complement(6355..6636)
                     /gene="vapD"
                     /locus_tag="PRVEN3_P3090"
     CDS             complement(6355..6636)
                     /gene="vapD"
                     /locus_tag="PRVEN3_P3090"
                     /inference="COORDINATES: ab initio
                     prediction:Prodigal:2.6.3"
                     /inference="similar to AA sequence:UniProtKB:P71351"
                     /codon_start=1
                     /transl_table=11
                     /product="endoribonuclease VapD"
                     /protein_id="BCT08355.1"
                     /translation="MYAISFDLVVAETSANHPKGVSQAYIDIATTLGNFGFQRVQGSLY
                     TNHNEDMANLFNAMTALKAMSWFPKSVRDIRAFRIEQWSDFTKTIKTP"
                     /name="vapD"
     gene            complement(6639..6830)
                     /locus_tag="PRVEN3_P3100"
     CDS             complement(6639..6830)
                     /locus_tag="PRVEN3_P3100"
                     /inference="COORDINATES: ab initio
                     prediction:Prodigal:2.6.3"
                     /inference="similar to AA sequence:UniProtKB:P43998"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="BCT08356.1"
                     /translation="MMTINKIPTGAIKTFGNYGVLYQVGEKDSDLPDGDILVNITLLES
                     GEKEKYKLSQLIEDPEAK"
                     /name="hypothetical protein"
     gene            7291..7911
                     /locus_tag="PRVEN3_P3110"
     CDS             7291..7911
                     /locus_tag="PRVEN3_P3110"
                     /inference="COORDINATES: ab initio
                     prediction:Prodigal:2.6.3"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="BCT08357.1"
                     /translation="MIISCIGQKGGGAKSTIARTLAVGFTEAGWKTHLADIDEKQQTSL
                     KWCKRREDAGLAVVDCALYRRVETAVKIKDQYHLLIIDGRPAAETTSLDVALESDLVLV
                     STGTTIDDLEPSLELVRELIKKGIDKDKITFIVAKSPSDSEGVKAQETIRAWGFNVLNS
                     IIPFKTSYGNALDLGRALNETSFKSLNLIAKNMIEEVHDIINS"
                     /name="hypothetical protein"
     gene            7962..8189
                     /locus_tag="PRVEN3_P3120"
     CDS             7962..8189
                     /locus_tag="PRVEN3_P3120"
                     /inference="COORDINATES: ab initio
                     prediction:Prodigal:2.6.3"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="BCT08358.1"
                     /translation="MKAPKSNIKLTPPQDNEPTLDVTGKGAKPDTDIKPIQIKIPVNKH
                     KEMKAYAAEQGISMTEMLLTGYEMYRSKMN"
                     /name="hypothetical protein"
     gene            complement(8341..8835)
                     /locus_tag="PRVEN3_P3130"
     CDS             complement(8341..8835)
                     /locus_tag="PRVEN3_P3130"
                     /inference="COORDINATES: ab initio
                     prediction:Prodigal:2.6.3"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="BCT08359.1"
                     /translation="MKSLSIIFISLFTLNGCAYYSHQFGLGDHSAFCSNIENDRDRHNE
                     KYYISGSQFFYITKNGDYYSEKEFNQLTSPTLINVSYGGLSAKELKDTAKKAFTVKFTN
                     TNTNKNICSSTLVSSDSYEKNYMDSILGRKLLISSEKGKGASGKEIYRDEGKKSLSIQY
                     L"
                     /name="hypothetical protein"
     gene            complement(8860..9450)
                     /locus_tag="PRVEN3_P3140"
     CDS             complement(8860..9450)
                     /locus_tag="PRVEN3_P3140"
                     /inference="COORDINATES: ab initio
                     prediction:Prodigal:2.6.3"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="BCT08360.1"
                     /translation="MGRIFIYCRCSKVEQDTENQVMAIRNWRAEFKNIPDYRVVNETIS
                     GGVPAMQRPHFANLVNNKLEAGDSLVVLKLDRLGRDNIDIQKTISLLSEKEINLICLDL
                     PIADLMSAEGKLMMQLFASFAEFEKSRIIERTHEGLRKAKAKGVTLGRPKGSSIHKEAI
                     QIAKEAGLSQSKVAKHLGIGIATVKRHWNANKI"
                     /name="hypothetical protein"
     Typing          complement(5188..6041)
                     /name="rep_cluster_1478"
                     /typing="replicon"
                     /tool="MOB-suite"
                     /identity="95.439"
                     /coverage="100.0"
                     /evalue="0.0"
     Typing          1971..3379
                     /name="MOBP"
                     /typing="relaxase"
                     /tool="MOB-suite"
                     /identity="92.766"
                     /coverage="100.0"
                     /evalue="0.0"
ORIGIN
        1 attcttttat tttttataac gctccctgct ttattaagaa cactactttt tagaagaaat
       61 aagacaattt ggtatagata acttataaat aggaataatt atgtctaagt ttaaatgttc
      121 agtattagct ttaacggtat tagctttgtc tggttgtggt gagaaaagcg atatagagaa
      181 cgcgataaat aaaaacatag aaaataagga gtattgttat agcctacaag ataatgatat
      241 ttcatttcct atcacaatag gacgagataa cttttctcaa gatttttcac ctattttaaa
      301 aggattagct aatcaagggt tagtaacttt acataatcaa ggttataggg attatgttat
      361 aagcttaacc gaaaaggggg ctaaaacaga tttttgggat aaaaaacgtg gtgtgtgtat
      421 ggggaaacgg gttgttgacg atataaaaga gtggactgaa ggtgagcaaa atacaatcat
      481 ggtcacatat acagagaaat tagttgatgt tcctcgttgg gtagataaaa agtctttctc
      541 tgatattgaa ggaatggata gccctgcaga gaaacgtgct gttttaaaaa aaacaagtaa
      601 tggttggaaa gtttggaatt aatataaaac gttttcaaaa aaacacagaa agcagacaaa
      661 acaagttttg cctgctttct gtgttgtcat aactaaattt aatagtattc gatagataaa
      721 aatttgacat taccttttta tgtattattt attttactaa ataatcgatt aaataactat
      781 aaagaggttt ataatgaatt ataatttacc aagcccagag gaaatgatta aacaattagg
      841 tgatttaatt aataaaagga atgaaaaaga gagattggga gattttttca ataatgatta
      901 tttttctgag atcagaaaat gtataaacaa tgaagtttct gaaataaaaa acatggaggt
      961 taaaaggtca ataaaaggtg catatttaag cgcttgtata aaaagataca aaaggaacat
     1021 agtaaaagac tacatactta aaatagcgat tattgagggg ttagacctga ctcagaggat
     1081 agcagatcta ttttttattg aatgcctagg aagaagtgtg ggagagttct ttctcaatga
     1141 gcatttttct ggattgcaat ataaagaaaa taaattaact aaaataaaaa gaacgagtga
     1201 aaatattgta ttaaatccag taaaaaaaga agaagtaaaa ggaattatag caaaatataa
     1261 aaatcaaatt atcgactcag tagaaaaaat aaaatgttat ttttacgaag ctaagctttc
     1321 ttgaaatact attgctattt aatcgactat ataactttta ctatctaagc taattaatcg
     1381 attaattgat attaataact aaagctaaat aatcgattaa atagctttaa atgtaaatat
     1441 ttgactttta ttttatttga tttatttact ttatatgtga gagagcaagc tcagacaata
     1501 ctgcgtattg tcgcttgtga ggggttggct tcgccctccc cttcaatccc cacccaaggg
     1561 cggaaaaacc aaaagacaaa atcaaaaccc aatcggaggt gttatttatg gaagtgaaaa
     1621 agttttataa agatcgctat cagcgaaaaa attctgtgcg tttatgtttt aatgatttgg
     1681 aattttccat tgtcgaacaa atagcaaaag ataaaaggaa aagcaaagct accgcattgc
     1741 gtgaatttat tctcgataaa gaaataaaaa taaaaaaaga cattcagtta acagatcaat
     1801 ctggtgttta ttatgagtta cataaaatcg gtgtgaatat aaaccagatt gctaagaaaa
     1861 tgaatacaga cttagagcag ttcttatcag gcaatggtga ggaattcgct tatttaattg
     1921 aggaaatctt cgaatatatt gaatatataa aaaacaggat aaattaatta tgtatcataa
     1981 aattataggc ggtatcgcag atagaaaaca acgaaatata aaaaatgcgg ttaattattt
     2041 attaaggata agtaaaccag aagagcagat acacgttaaa acgctctcta tgacgtcaca
     2101 acaagactta ttaaatttta ataacttcat attaccaaag aataaaaaat cgccctacgt
     2161 gtgcggtgtg ctctcatttg aagaagaaaa cattaatgaa gacttaaaag tcaaaattat
     2221 gtctgatttt gaagaaatgc ttttttcagg gatagaacta acgaatagac cgcctttaat
     2281 gtgggttcag catactgaca aagatagatt agaactcaat tatttaacat ttaatgcatt
     2341 ggctgacggt cgttctttta ctgcttactt tgataagaca gatagaaaat tattcaacac
     2401 attttcagag atcataaatt atgaaaatga tttttccagt ccattagaga agttagataa
     2461 aagaaacaca ttgataaata aaccaaatcc tcaagttccc aaagataaaa agcttcttat
     2521 tgaaaatctt aacaatgaaa ttatggggaa aattatgatt ggcgaattag tagatcgtaa
     2581 cgaagtaata aaatacatag aatcaatagg ttataaaata aatagagtaa gaaaaaatgc
     2641 gataagtata aagttagaaa atgacgacaa acccattgtt ttaaaaggag atatttatga
     2701 agagggtaga atatacgcag attatagaag agagccagaa gttagcaata gaagagatcc
     2761 agaagttgtt aaaagcgcac tcaatcaatt tagagacgac tttgagcgat tgcttagcaa
     2821 acgacaagat aaacatagaa aacgctttaa aagctcacag agaagcattg agaaaagcat
     2881 tgagagcaga gttaacagcc aagatttgga tcaaaatttt gaatttcaaa attcatttgg
     2941 gattgggggc gttactttct ctaagtctaa tttatatcac gatattaacc ataataataa
     3001 ttttaaaata gaggaggaaa acagtgagtt atatattaga acgaataaga gaaaagaaaa
     3061 aacagaagca gaaagatttg aattattacg aaatagaata cttgaagcta aacgagtcca
     3121 gaaatcaatt gatcatggaa ttgagagatt tagagatcag cagcatagaa ttcgagactc
     3181 aattagaact actcaattca gaaatggatt tgttagagga tacgttgcta gatttagcga
     3241 actatttaac gaaatcttgc gaagagcttt cagctttagt ctcagagcta aaaccctcga
     3301 agagcgcaaa gaaaaagcaa aaatcctcca aaaagaaaaa gcgtccgaac tcaaaagttc
     3361 aggaagaaag tttagagtca gatattgaaa atataaagcg tatggttgat tttttaatgt
     3421 cacaatataa aaaagcaata gaaaataaga agaaagaaac tataaagggc aattgatttg
     3481 cccttgaaat catagctata taatcgatta attcgtctaa tgaaaaaaca agccattgtg
     3541 tctttagtat atgttttatt tttcaatctt tagatttgaa tttatgaaat cataaatgtc
     3601 atcaagataa ctaattgttt ttacttttaa aataatttta tcatttgaat atttaagttc
     3661 tttttcttca taatcctcaa ttatttcatt aggagatgtc agtattttct ctattatatt
     3721 ttcacttata gttggaagcc gaaaactagg gtttacttca tattctacat caaatttata
     3781 agattcattt attgttttag cggaaagagc tgccgttttt tcaactaaac tttcattgcc
     3841 aacgcgaata cctctgtctt tatgtgggtt ctttcgaatt ttatctaata tatttaattc
     3901 tgtatatatc caaggagagt atgtgctttc gctttctgag tttatgttag atatggaatt
     3961 ttctgtattt aaaaatatac aacagtcact tttatctata gtatccatta atgcatttga
     4021 taaggtaaga taaaagttag tcccaactct tagactgcta tcgtatctaa gtaagtggtc
     4081 atttggtttt gggtttttag aatagttgac gtttatttca taaatagcgt tatcaacaaa
     4141 ttgccaaaaa taagaatcta taaatgtttt tattttataa tttgcataaa ggtaattagc
     4201 tatttttatt gctatatttt tatctttatg actatgagac ataaaaatat gacaatcaga
     4261 ttctgggaac caatttttta ttatatcagt atgctttatt tttacttcct ttttttcttc
     4321 atcaatatct aatattgact taatctcttt tattaaattg tcttgaccat aattataaat
     4381 taatgaatta taattattta tatctttatt tagaagttta ctatctaaag attcattatc
     4441 tatttttaaa ttgaatttat gtagcatgat tcaccttgtt atattaaata gcttccaatt
     4501 attaaacttg atatcattat gaagtaatac ggtataatgc taattgtgaa gtatacagat
     4561 aagtaggaag ttttgacctt ctttaaagat attatagtta atgaattctt tatgtcttca
     4621 ttatcaatag attctacctt tctattatac tcatttctaa aaattctctc ctgttgtaaa
     4681 tagtatgtat ctaataatga aaacataaat aatattataa tagataatgt tattacgata
     4741 ggaattgagt ttggggagta tgattctatt tcatccaatt ttggtataag tgcgatgata
     4801 actgcactta ttgataaagc ccatcccttt ataaaaaatg agttagatgc cattcttttt
     4861 attatgtctt gaatataacc tagtgacgat ataattgatt catttttatc catgaaatat
     4921 ctcctatcca attaaattta aatcttgttg cttgtagcgc ttagctaatg atttaacggc
     4981 atcgattgta gcattcatgc tatcagcaac ctctctccag gctaaacctt tctggcgaag
     5041 ttcaaacgct tgttttctgc gagctgcagc ttcttgttcg taatcttcac gatcctgaga
     5101 atagtatttt tttactgttg cgattgatac accatattca aatgctaaat cttttgcttt
     5161 tgtgtttctt ttttgatttt taattttcat agtaattcat tccttagtgc agcgagtaga
     5221 ttagctgctt ttttcttcgt cttagtcttc cctaggtttc tttttcctcg ctcactttgt
     5281 atttttgaaa attgttcgga gctaaaattc ttccataccc actttccaac gcttcttgct
     5341 gttgctttaa tttcgttaaa aggtaataaa ttagtcggat ttgaataagt attgagatta
     5401 attgcttgtt tttcgatttc attcatccag tgatgaaaat cgctgacgtc tttaaatttt
     5461 aaaacatttt tataagcata atgccttaag tcgtcaaaaa ggttgacgtt gcgacctaat
     5521 ccaaagcttt catacttagt ggtctcttta tttgtgtttt ctagtgtaat gaaatcagct
     5581 aaataatcga gttcatataa atccgcatta ctccagtgtg gtctccagtg tggattgaat
     5641 gggtttttag ttattaagcc tgcaaatccc tgatctgctt ttaggctttt ccccatttct
     5701 aactcaactg cagcggcata acgtaaaggt tctaactttg cgttttgcgt cttacatacc
     5761 cctcttttta gtatatatcc catatgacaa cgcccatttt ctgggttttg agttgtaaaa
     5821 tgaggaactg ggaggtgtgc ttcttcaaaa tcataaaagc tgttatctct atctatatca
     5881 aacaataagc atgtttgaat tgaaggatta tttatctgta agtaaagcat atctaacgct
     5941 ttatttttag gtcttatttt tagcccgtaa tctaggttat cactgcaata tggcttattg
     6001 ggaagttgac taattattgt ttcttggtta tcgttataca tgaataaaca attccttgta
     6061 gttgaaaccc tgcacttaag tttgccgacc agagtgtggg gttttgtttt ttataagtta
     6121 taactccttt tttctttgtg tcaagtgtct aaattaacca tatcagataa cagccaactt
     6181 ttgggtgggt tttcatacta aaaaggaaaa ctgtttattt agatcattgg tcgtgtcaag
     6241 tgtctagatt aaccatatca gataacagcc agatcttctg gggggtttta gatcatagga
     6301 aagtaatgct atttataaaa aaggactgat ttttcagccc ttttccttat attgttatgg
     6361 cgtttttatt gtcttagtga agtctgacca ttgttcaatt ctaaatgctc taatatctct
     6421 tactgacttt ggaaaccaac tcattgcttt taatgcggtc attgcattga ataagttagc
     6481 catatcttcg ttgtggtttg tgtataagct accttgaact cgttgaaatc caaagtttcc
     6541 cagtgttgta gctatgtcta tgtaagcttg cgatacacct ttagggtggt ttgctgatgt
     6601 ctctgctact actaaatcaa atgaaattgc atacataatt atttagcttc tggatcttct
     6661 atgagttgag ataatttata cttctctttt tcgccacttt ctagcagggt gatattcact
     6721 aaaatatctc cgtctggaag atcgctatct ttctcgccaa cctgatatag aaccccatag
     6781 ttcccaaagg tttttattgc tccagttggt attttgttta ttgtcatcat gaaaacctcc
     6841 tttgagatca ataaatctga ttgtttttta atctaatact actcttttgt caatttgttc
     6901 atatgaatag tgtcaagcgt ctatttaacc atatcagata tcagcggtat ctaagcgctt
     6961 ttgtatactg aagggaaagt agtaatttac tttgtttaat tgatcgagat ccaaaagaga
     7021 tccttattta gatcatttgt tagacttcct ctatcccatt ttgcggcgtt ttttacattc
     7081 accctttatg atttcctatt tattactcaa aactcaatca agcgcgttat acggcgttta
     7141 gcatgtggtt ataaaaatta gccaatattt ctattgaatg tgacttattt ttctatcatt
     7201 aaatcatgat agcatgaagt tttattttaa tatcaatcta aatgtggcaa tatagccaac
     7261 tacaacatga aataatgaaa gagtgaaatc atgataattt cttgcattgg tcagaaaggt
     7321 ggcggcgcaa aaagcactat agctagaacg ttagccgtag gttttactga agccggttgg
     7381 aaaactcacc ttgcagatat tgacgaaaag cagcaaacct ctttgaagtg gtgcaaaaga
     7441 agagaagatg ccggcttagc tgttgttgat tgtgcattat accggcgagt tgaaactgca
     7501 gttaaaataa aagatcaata tcatttgcta atcatcgatg gaagacctgc agccgaaaca
     7561 acttcgttag acgtagctct cgagtcagac cttgttctgg tttctactgg aacaacaatt
     7621 gacgacttag agccatcatt agagttagtg agagagctga tcaaaaaggg aatagataaa
     7681 gataagatta cttttattgt tgctaaatcc ccgtctgaca gtgaaggcgt taaggctcaa
     7741 gaaacaataa gggcttgggg ctttaatgtg cttaattcaa taattccttt taaaacgagc
     7801 tacggaaacg cacttgatct agggagagca ttgaatgaaa cctcatttaa gtcattaaat
     7861 cttattgcta aaaacatgat tgaagaagtt catgatataa ttaattcatg atatcatgaa
     7921 ttggtattgt aaataaaatt gattaattag tagaggtgag aatgaaagcg ccaaaaagta
     7981 atatcaaatt aacaccacca caagataatg agccaaccct tgacgtgaca gggaaaggag
     8041 cgaagcctga tacagatatc aagcctattc aaataaaaat tcctgttaac aaacataaag
     8101 aaatgaaagc gtatgctgca gagcagggga tctcaatgac ggaaatgtta ttgactggat
     8161 atgaaatgta tcgaagtaaa atgaattaat gaaatcatga tttcattaat ttgtttgtgt
     8221 tatatcaaat agttagttgg atttttaatt gtttgttatt tttacattca gtattttctt
     8281 atttgaatat tttgtatttc agtaataaaa tgccagtatc aaaaaccgaa cggttattat
     8341 ttaaagatat tgaattgaaa ggcttttttt gccttcatct cgataaatct cttttccaga
     8401 agctcccttg cctttctcgc ttgaaataag aagttttcta cctaagatag aatccatata
     8461 gtttttttca taagaatcag agctaactag tgttgaagaa caaatatttt tgtttgtatt
     8521 cgtatttgtg aatttaacag tgaaggcttt tttggctgtg tcttttagct ctttagcaga
     8581 tagcccacca taggaaacat tgatcagtgt tggagaggtc aattggttga actctttttc
     8641 agagtagtaa tcaccgttct ttgtgatata gaaaaattga gagccactaa tgtaatattt
     8701 ttcgttatgt cgatctctat cattttctat attagaacaa aaagcggaat ggtcacctaa
     8761 cccgaactgg tgagagtaat atgcacagcc atttaacgta aataatgata tgaatatgat
     8821 tgataatgat ttcatgctaa atattactct ttgaattatt taaattttat tagcgttcca
     8881 gtgtcttttt actgttgcta taccaatacc taaatgcttt gctactttgc tttggcttaa
     8941 acctgcttct ttggctattt gtatagcttc tttatgaatg cttgatcctt taggtctccc
     9001 cagtgtgacg cctttcgctt tggcttttct taatccttca tgtgttctct cgataatccg
     9061 agatttttca aattcagcaa aagaggcaaa aagttgcatc attaatttac cttctgcaga
     9121 catgagatcg gctattggta aatcgagaca aattaggttt atttctttct cacttaataa
     9181 gcttatcgtt ttttgaatat cgatattatc tcttcctaag cgatctaatt tcaaaacaac
     9241 taacgagtca cccgcttcca gcttattgtt aaccaagtta gcaaaatggg gacgttgcat
     9301 tgcaggaacg ccaccactaa tagtctcatt cacaacccta taatctggaa tatttttaaa
     9361 ttctgctctc caattacgta ttgccataac ttggttttct gtatcttgtt ctacctttga
     9421 acacctacaa taaataaaaa ttctacccat aactttatcc tcctaagaat cattaatcgg
     9481 tatcataatg ttttaaggta tcaataagtt atgtcaatgc ttttgtagcg aataaagtta
     9541 cctatatccc taatatcaat aaccgttcgg tttttgatac cgtaaaaata cgtaggggga
     9601 ataggtatgg ctgagtgtcc attttgtaaa tcagaggttc atgatgaagc ttcgatatgt
     9661 cgaagctgtg gagctgagaa agttgactca ttcggggggc actttaataa agcatttaaa
     9721 gagactcaac atggagtagc gccattaggt tttgtaggat tgcttattgg ggggcttttg
     9781 gggctttcag tcggcatgaa ttcaaatggt gttctaggtt ttattgtatt catactt
//
