LOCUS       NZ_LR135411.1           6510 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_LR135411.1 Enterococcus faecium isolate E8284 plasmid 4.
ACCESSION   NZ_LR135411
VERSION     NZ_LR135411.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-06-07 16:51:27
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6510
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..6510
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[1135:1510]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1136..1510
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..6510
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..6510
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             complement(3..1082)
                     /locus_tag="ctg1_1"
                     /transl_table=11
                     /translation="MLKKINAVLSLFVCITILFFSTNVINGIKTSEALYKNTAEIHMQY
                     KDDMDFNSYINALYEISTQENINISQYSFTAVNQLTILATNPNANKHWKFSKKNILARN
                     DSKVHYTNNKNSKYQLKLPNNFLNINIYPFSHVENIGLSEILYVQGNSNKLIPVLKKYG
                     TPTISNINQSDTFQINTNIVLVICYLSIFIVITTIIFAFSKMKEITLKKMLGYNSFDTI
                     KDSIKELNLLFCSLIITFILSIFLSIYYSNENFFLSFLLCSIFHFIISFLFIIVTLSIY
                     HLSSIKNYLKNSRPLKLNLCILNICLFLSMILLLIASTKVINTHNEAENNSLKYWERTT
                     NLYKTNITNQLNRNNTVEEN"
     CDS             complement(1136..1510)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Lactococcin_972"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2"
                     /sec_met_domain="Lactococcin_972 (E-value: 1.7e-09,
                     bitscore: 28.1, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKFLCLSALMGVLLTSGGIASATEALNLDVPEDHTAIYGGGMEA
                     TEEGFSSSKLRYAAGGGDFNCGVNGFKVYANYYHARAKHSATAKNGRGGQVRSVQKAGV
                     RAYATCNATLTGNTGWWNVY"
     CDS             1643..2104
                     /gene_functions="other (smcogs) SMCOG1148:hypothetical
                     protein (Score: 61.9; E-value: 1.6e-18)"
                     /gene_kind="other"
                     /locus_tag="ctg1_3"
                     /transl_table=11
                     /translation="MEDLGSKLRELRVKKGYTQEYVARKFNVTRQTISKWENNKTTPDI
                     ETLKKICEFYSTNINSILNEDNSKNKKNNLLVLTAIIFNIFVTILGLFELIQMNFFSFT
                     HGIFTWFALSGLIVIDILNYFYIYYSYLKNEKFFYTMFFPLVILIILLS"
     CDS             complement(2416..2586)
                     /locus_tag="ctg1_4"
                     /transl_table=11
                     /translation="MTRKNLLFGSILLGILGFSPMLLSVINKGNKHGELKLNPNYYNSP
                     NEELFVKETDK"
     CDS             complement(2602..3141)
                     /locus_tag="ctg1_5"
                     /transl_table=11
                     /translation="MQPKETFTIKELSELFEISRQAISKHVDKLDPSLLAKNERGYKVV
                     LRSGVLQLASNLGNQRLLYRLHEYEQENDKNVYISSKNVIVNELLDKLREENEFLREQL
                     SLKEQNNSNMQKLLDQQQQLTLQANQQIEKLQEQLQLAYTEETPEDESTTILSEETESI
                     EKHTKKKKQKWWQLWK"
     CDS             complement(3169..3906)
                     /locus_tag="ctg1_6"
                     /transl_table=11
                     /translation="MSNDIVRYNNGLNSVPLRKFTPIDMDLFWGICSKMKRKGTKEEIF
                     TFKQIKELIDYNINARGDRFANDLIKMSKKIITLSFIYEDEKTYEQLNLFQKFKIDKVN
                     ETLLIKVSEEFEYILNSIGTNFTRFELENMTNLKSSYVKELYRQLMAHKDRRSKKGHWF
                     VKIEDFRALLAIPESYRMRDIDKQIFAQAKKEFLNVNSTHPAIFKTFEIKKIKAYKGNK
                     IGSLQIYFEENIPSITLDNWLEK"
     CDS             complement(4758..5447)
                     /locus_tag="ctg1_7"
                     /transl_table=11
                     /translation="MAFYLPYLLIFVSISGSIWLIYKIFQTRYSLKGSKIRFKRFFFLG
                     CIFSLIIVSSGLFGVLEGNKRVSRSILLGNVTQKYESARDKKKKEQALAQKMEEFTTCY
                     EEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYVKDTKIEEA
                     CSDLFGDTNPWFASEEEKKEKQQSVTYERYEILLQQATNMQNPTKKETALNYLKSVKEW
                     LDQQQQN"
ORIGIN
        1 ttattttctt ctacggtgtt gtttctattt aattgattag taatatttgt tttgtataaa
       61 ttagtagttc tttcccaata tttaagagaa ttattttcgg cttcattatg ggtatttatt
      121 acttttgtag aagctattaa cagaaggatc atgcttaaga atagacagat atttaatata
      181 caaagattta acttaagtgg tcgtgaattt tttagataat tttttatact agataaatga
      241 tagatactta gagtaactat gataaataaa aaactaatta taaaatgaaa aatactacat
      301 agaagaaatg ataggaaaaa attttcgtta ctgtaatata tgctcaaaaa aatagataaa
      361 atgaaagtta taatcaaaga acaaaataag aggtttaact ctttaataga atcttttata
      421 gtatcaaaag agttatagcc taacattttt tttagagtga tttctttcat ttttgaaaaa
      481 gcaaatataa ttgtagtaat tacaataaat atactaagat agcagataac aagaacaata
      541 ttagtattaa tttgaaaagt atctgattga ttgatattgg aaatagtagg tgttccatat
      601 tttttcagta caggaattaa tttgtttgag tttccttgta catataatat ttcacttaat
      661 ccaatatttt ccacatgaga aaaaggataa atatttatat ttaaaaaatt atttggaagt
      721 tttaattggt acttagaatt tttgttatta gtataatgga ctttagaatc gtttcttgct
      781 aatatatttt ttttagaaaa tttccagtgt ttgttagcgt tagggtttgt agcaagaata
      841 gttagttggt taacagcagt aaaactatat tgagaaatat taatattttc ttgtgtagat
      901 atttcataca aagcgtttat ataactgtta aagtccatat catctttata ttgcatatga
      961 atttcagcgg tatttttata tagcgcttca gaagtcttta taccatttat aacattagta
     1021 gaaaaaaata gtattgtaat gcagacaaaa agtgataaaa cagcgtttat tttttttaac
     1081 atattttgaa tttcctttca aatgtaaata aaaaagagag tttaaactct cttttttaat
     1141 aaacattcca ccaaccagta tttccagtaa gtgtggcatt gcatgttgca taagctctta
     1201 ctccagcttt ctgaactgat cgtacttgac cgcctcgtcc atttttagct gttgcactat
     1261 gtttagctct agcatggtag taatttgcat aaactttaaa tccattaacc ccacagttga
     1321 aatccccgcc gccagcagca tatctcaatt tactagaaga aaatccttct tctgtagctt
     1381 ccattcctcc tccgtaaatg gcggtatggt cttcgggtac atctagattt aaagcttctg
     1441 tggcactagc tattcctcca ctagttaata agacacccat taaagcagaa agacataaaa
     1501 attttttcat aacttatttc tcctatcttt tttactagaa ttattttatt ttagtgtgtt
     1561 ttataaaata aagaactttt ttggcgcgtt agtattttta tgataaaatt ttatgtaaat
     1621 aatcgtttac ataggagaaa aaatggagga tttaggatct aagctaagag aattaagagt
     1681 gaaaaaaggg tatactcaag aatatgtggc aagaaaattt aacgttacac gtcaaactat
     1741 ttcaaagtgg gaaaataaca aaacaacacc agatatagag acactaaaaa aaatttgtga
     1801 attttatagt actaacataa attctatttt aaatgaagat aattcaaaaa ataaaaaaaa
     1861 taatttactg gtattgacag ctattatttt taatatattt gttactatat taggtttatt
     1921 tgaattgatt caaatgaatt tttttagctt tacacatgga atatttactt ggtttgctct
     1981 atctggatta atagtaatag atatcttaaa ttatttttat atttactatt cttatttaaa
     2041 aaatgaaaaa tttttttata caatgttttt ccccctagtt attttgatta ttttattaag
     2101 ctaatatgaa gtagttagtt atttaattgc atagttgaca taatgtcgac tatgccaagt
     2161 agcccctcta tcaagggcta tagctgctca ctttgtgatt tttaattggt ctagctaaaa
     2221 gcaactttct aaagcttgat ttttcgcggt tatctatatc taattctttg tgcattttta
     2281 tctgtcattt ttttaagact tgttattttt tgtaaaatat ggtaaatttt tggcagcgct
     2341 tcataagcgc gtgctttttc aagaataaac actcattatt ttttaactgg ctgctcggaa
     2401 gagcagtctt ttttattatt tatccgtctc ttttacaaac aattcttcgt taggactgtt
     2461 gtaataattt ggattcaatt tcaattcacc atgtttattc cctttattga ttactgacaa
     2521 taacatcgga ctgaagccta gaattcctag taaaatagaa ccgaatagaa gattttttct
     2581 tgtcatgaat gttccctcca gttatttcca aagttgccac catttttgct tcttcttttt
     2641 tgtgtgtttt tctatcgatt ctgtttcttc agaaagaata gtagttgatt catcttctgg
     2701 agtttcttcc gtataagcta attgtaactg ttcttgcagt ttttcgatct gttgatttgc
     2761 ctgtagggtg agctgttgtt gctggtcgag taatttttgc atattagaat tattttgctc
     2821 tttgagggaa agttgttctc gtaaaaattc attttcttca cgcaacttat ctagcaactc
     2881 gtttacaatc acgtttttgc ttgatatata aacgttttta tcgttttctt gttcatactc
     2941 atgcaaccta tatagtaacc tttggttacc taagttgcta gcaagttgca atactccaga
     3001 acgtaataca accttataac cacgctcatt tttagctaat aaggacgggt ctaatttatc
     3061 aacatgttta gagattgctt gcctacttat ttcaaataat tcagataatt cctttattgt
     3121 aaaggtttct ttgggttgca tgataattgc ctcctaaatt gttaggtatt atttctctaa
     3181 ccaattatct aaggtaattg aaggtatatt ttcttcaaaa taaatttgca gagatcctat
     3241 cttatttcct ttgtaggctt taattttttt gatttcaaaa gttttaaaaa tagcagggtg
     3301 agttgaatta acgtttaaaa attctttttt cgcttgggca aaaatttgtt tatcaatatc
     3361 tctcatgcga taactttctg gtattgctaa tagagctcta aaatcttcta tttttacaaa
     3421 ccagtgacct tttttagatc ttctgtcttt atgagccata agttggcgat ataactcttt
     3481 aacgtagcta ctctttaagt ttgtcatatt ttctaattcg aaacgagtaa aattagttcc
     3541 gattgaatta agtatatatt caaattcttc agaaaccttt attaataatg tttcattcac
     3601 tttatcgatt ttaaattttt gaaacagatt taattgttca tatgtttttt cgtcttcata
     3661 aataaaagac aaagtaatga ttttttttga catttttatt aaatcattag caaaacggtc
     3721 gccacgtgca tttatattgt aatcaattaa ttcttttatt tgtttaaatg taaaaatttc
     3781 ttcttttgta ccttttcttt tcattttaga acatattccc caaaataaat ccatatctat
     3841 aggggtaaat tttcttaaag ggacagaatt taatccatta ttatatcgaa ctatatcgtt
     3901 actcaataaa aatcacctca ataaattatg ttatcataga cataagagga tgtaaaacac
     3961 aatttatccc ccatagtgtg acaatttatc ccccatagtg tgacaattta tcccccatag
     4021 tgtgacaatt tatcccccat agtgtgacaa tttatccccc actacctatg tcaatactta
     4081 ctctcccata aggttgctaa tccctaacag ttattattaa cagtatatct aacagtatat
     4141 ctaacagtat atcttaagag cacattgaat ttcccgccta aaaaactcct actttttcct
     4201 ccaaaaaggt tcgcgaattt ttctaaactg gaaaacttgc tccctacggt cgctaaaaag
     4261 gtgtgatcgc tatgctctca tattatactg cgcagtcgcc tccggctcct ttgctaaaac
     4321 cgttgttcaa agaggaggtg tgagactctg aaagcttgtc taagccgttc taagacaatt
     4381 cttgattaat ttcccttaat ctagtcgaga agcgccttac aggcggtcag ggcaagccct
     4441 aacaacccta aaacaagtga tacttaaaaa caccacacaa atttaatttt ttaagatata
     4501 ataacttgtc gcctatccga cagtcttgcg actggaagga ggtgtatcta atgtttgaac
     4561 tgttcatttg cccccttctt gtaggagttt gtgtctcttt attcagttat tggttgaata
     4621 accgaaacaa gaagtaaaat caataaaggc gacatcaacc tgaaaaaaag ccccagagaa
     4681 tccgacctct ctggggcttt cgtgtatcta atgtttgatc atttgcacat tcagtttaac
     4741 atgattttaa atcaaattca attttgttgt tgctgatcta accattcctt gacacttttt
     4801 agatagttta aggcggtttc tttttttgtc ggattttgca tgttagttgc ttgttgaagt
     4861 aagatttcat agcgttcata tgtgacagat tgttgttttt cttttttttc ttcttcactg
     4921 gcaaaccaag ggtttgtgtc tccaaataga tcactacagg cttcttctat ctttgtatct
     4981 tttacatatt gcacgtcttt tttggttcgc tcatagttgt cttgaacctc tttttgctgt
     5041 ttttctggca agttttgata aagacgagtg agtttttcca tgtttttatc cgtcaaacgt
     5101 ttttcttgat tcacaaaaat atcgttcatt tcctcataac aagtggtaaa ctcttccatt
     5161 ttttgtgcta atgcttgctc ttttttcttt ttatcacgcg ctgattcata cttttgagtg
     5221 acatttccta ataaaatact tctagaaacg cgcttatttc cctctaaaac gccgaataag
     5281 ccgcttgaaa cgattatcaa ggaaaatata cagccaagaa agaaaaatcg cttaaatcga
     5341 attttagagc cttttaatga atatcttgtt tgaaaaattt tatagatgag ccaaatactt
     5401 cctgaaatac taacaaaaat gagtagatag ggtaaataaa atgccatttt agcctcccca
     5461 tactaaccaa aatgcgaaca gtgtcaggac taagcaacat aagggggcaa gaaaatccaa
     5521 tgatcgttga ataagcacct ttttctgttc cttatttcgc tggtctaata gctcttgatg
     5581 gagtttttta acttgtaaat caatcgtagt ttgtatcctt tcttgcgtat aaggaacgag
     5641 aaaagcacgt tgtttcttta tttcgttttc tatgtctttt aacgttttag agcgataatt
     5701 cttgttggtg gtctgttcct ctttcaacgt gttgttcatg gtttcttcga gccggtctaa
     5761 tttccggttg ttcaggcgta agagttcgtt gttctcttcg tacttcttct gcagtttcgc
     5821 gaatgctagc tcgagctctt cgtagctcgt tggttcgctg ttggttatag gttcgttctc
     5881 gtctgtccag ctcatgtaaa atcgtctcct tttcgtagtc ctttcctagt ctgttggatc
     5941 gtactttttt ctttttgtgg atcaattcgt aagtgaaatt tttcccgcga ttgaagcaat
     6001 gaatccccaa tgttttgagg gaattacaaa attggtcata ggttctggtt tttttgtttt
     6061 tcattgtttg atcgatcgca atccgaattt cgtctttcca aacaggttca tttttttctt
     6121 ttaattttat ttcagacatg gttcgttttt ctggtttctt tcctcgctca gtgattggta
     6181 agttatgtgc aagacaaatc tcgtcattta ggtcataaca tttgtttaga aatgcttgac
     6241 catgagcttg aaattttttt ccagtctcca gattaacgga gttaatgaca atgtgattat
     6301 gaatatggtc tttgtctgta tgtgtgtaaa tagctgtttg gtgatcgggg gctatttttt
     6361 ttgcatactc tgcccctagt tgattagctt tttcagcggt aatttctcct ggtcgaaaag
     6421 attgaatcaa taagtgtgcc tgtacacggt cgtcttttcc atacagcatg cgaatttgtt
     6481 tcatttcact tttggcataa tcgacgtcac
//
