LOCUS       NZ_KY595970.1           5974 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_KY595970.1 Enterococcus faecium strain VREfm87 plasmid pMIS006,
            complete sequence.
ACCESSION   NZ_KY595970
VERSION     NZ_KY595970.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-06-07 17:35:20
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5974
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..5974
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[749:974]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      750..974
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..5974
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..5974
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             complement(443..790)
                     /locus_tag="ctg1_1"
                     /transl_table=11
                     /translation="MVGLIMVHGHLEGSGREVIIMDFTKEEKLLNAISKVYNEATIDDY
                     PDLKEKLFLYSKEISEGKSVGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQV
                     YRGWASIGIWS"
     CDS             complement(750..974)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_II"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2"
                     /sec_met_domain="Bacteriocin_II (E-value: 1.3e-22,
                     bitscore: 68.5, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEKC
                     WVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     CDS             complement(1429..1623)
                     /locus_tag="ctg1_3"
                     /transl_table=11
                     /translation="MEMKKEILMTKKHLLFGSILLGILSFSPMLLSVANKGNKKGELKL
                     NPNYYNSQNEEVFVEKLDK"
     CDS             complement(1614..2147)
                     /locus_tag="ctg1_4"
                     /transl_table=11
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKVV
                     LRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLREQL
                     ALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATETMD
                     EQTKNWKKWWQLWK"
     CDS             complement(2168..3112)
                     /locus_tag="ctg1_5"
                     /transl_table=11
                     /translation="MANEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMREKGDKTVRF
                     TFDQLKDLSNYKATANVRFVEDLKATYEKILSLRFGRRSESGLSYDMFVMFTEFKINGD
                     VENPYVDIRIYEKALPLLNNLDEWVRYSLQQFNELQSGYAKTMFRLLKQYRTKGFAYFS
                     KEDFLELLDIPKSYKQPDIDKRVIKPIRQELTAIFKGLTIKKKYGKGRGKPVIGYQFTF
                     KPEIKKADDFNKHAPTKEDQNKALALADKQKEYEEPATTINEKIKQKKRELELLQQIKQ
                     LEKEKKALEKQTESALSEKEKKSLLSDLDNLFQ"
     CDS             complement(3956..4645)
                     /locus_tag="ctg1_6"
                     /transl_table=11
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLPG
                     VIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTTCY
                     EEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQTEEA
                     CYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKSVKEW
                     LDQQQQN"
     CDS             complement(4890..5804)
                     /locus_tag="ctg1_7"
                     /transl_table=11
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIRM
                     LYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHNHI
                     VINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKLKEK
                     NEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKKKVRS
                     NKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTTEQPEI
                     RPTRRNHDQHVERGADYQQELSF"
ORIGIN
        1 accctttcag tacgtcctac ggacgtatcg ttcgcaatac cattgtacct aaaaaggtac
       61 aataagtaaa gctcactaaa gctcactaaa gggcttggca agctctatat ttgctagcca
      121 aatacctacg tatttggtgc aaataaccgc ttgtcaaagg ggcgcaagct cccccttgaa
      181 tccccctccc ccccactctc cacaatacaa aaaagactag caaatgctag ccactttttg
      241 taaagtttcg cttgtttcac cttcggtgaa attgttgcaa atcaataatt aggtagagct
      301 acattttttt cgttgttcaa agattcttat gccatttact attaataaat ctataaatat
      361 gataattttt cggctctata atttatggga ctgatgaatc agaattgatt cttcagtccc
      421 attttcattt tattccaaag aattaactcc aaataccaat agaagcccat cctctatata
      481 cttgagattc cttactaaca atttcttgta attctattaa agatttaggt aatccaaatt
      541 tatgttttaa aatatatctt ccaagaaaac tacttaattt catactaact tcaccaacac
      601 tttttccctc actgatttct ttagaataaa gaaagagctt ttcttttaag tcaggatagt
      661 catctatagt tgcttcattg tatactttac taattgcatt taaaagtttt tcttctttag
      721 taaaatccat tataataacc tccctaccac taccttctag gtgcccatgg accatgatta
      781 acccaaccat taacaataat ttttccaatt tctcctttag cttgattcca atctacccaa
      841 catttttctt tgttacaata aagaccattt ccatagtaag tagctgcatc aacttttatt
      901 cctgtaccga tgccagctag acaagttcct aatattccta gaataacaca atgttttaat
      961 actttctttt tcatgattgt ttttcctttt cgttttttta aaattgcttg ttatattaaa
     1021 taatcttagt aattttatta tataacattt tattatataa caatgattaa cgtcataaaa
     1081 agtagttttg aattcataat cgtttaaata aaattataag atcagttatt taaacagcta
     1141 gtagacataa tgtgtatact accaagtaac gcctgtacca agggatccag gcgctgattt
     1201 tgtgaatttt tattggtcta ggttaaaagc tctttttaag gcttggtttt ctgcggttgt
     1261 ttctttctaa ttctttgtga atattgatcg gtcatttttt aaatacttgt tatttttgtt
     1321 tgtgtttgtt atgcttttta catatctcat attcatttat tattcttttc taaggttaat
     1381 aataggataa tctctttcag aaagactgct cgtacgagca gtcttttctt atttatcaag
     1441 tttttctaca aatacttcct cattttgact gttgtagtaa ttaggattga gttttagttc
     1501 ccctttttta tttcctttgt tggccactga taataacatt gggctaaagc ttaatattcc
     1561 tagtaggata gaaccgaata gcaagtgttt ttttgtcata agtatttcct tcttcatttc
     1621 catagctgcc accatttttt ccaattcttt gtttgttcgt ccattgtttc tgttgcttca
     1681 gaaagagtcg ttgaactatt ctctgaagac tcttccgtat aagtcaactg cagttgctcc
     1741 tgaagttttt cgatttgttg gttggcttgc agggtgagtt gttgttgctg gtcgagtagt
     1801 ttttgtatat gagaattatt ttgctctttg agggcaagtt gttctcgtaa aaattcattt
     1861 tcttcacgca actgatctag caacttgttt gcaaccacgt ttttgtttgg tatataagca
     1921 tttttatcgt tgttttgttc atgtttatgc aacttatcta gcaacctttg attgtctaag
     1981 ttgcgagcaa gttgcaatac tccagaacgc aatacaacct tataaccacg ctcattttta
     2041 gctatcatgg aagaatctaa tttttggata tgtttcgata ttgcttgcct actcatctta
     2101 aaaagatctg acaattcctt tattgtaaag gtttcttgtg gttgcatact ggttgcctcc
     2161 taggttgcta ctggaataaa ttatctaaat cagataataa actttttttc tctttttccg
     2221 aaagtgcgga ctctgtttgt ttttcaagag cttttttctc tttttctagt tgtttgattt
     2281 gttggaggag ttcaagttct cgtttcttct gtttgatttt ttcgttaatt gttgtagcgg
     2341 gttcttcgta ttctttttgt ttatcagcta aagccaatgc tttattttgg tcttctttgg
     2401 ttggtgcatg tttgttaaag tcgtctgctt ttttgatctc aggtttgaac gtaaattgat
     2461 agccaataac aggttttccc cgtccttttc cgtatttctt tttgattgtt agtcctttga
     2521 agattgcagt tagttcttga cgtataggtt ttataactcg tttatctata tcaggttgct
     2581 tataactttt aggaatatct aataattcaa gaaagtcttc tttggagaaa tatgcgaaac
     2641 ctttggttct gtattgcttt aacagacgaa acatagtctt tgcatagcca ctttgtagct
     2701 cgttgaattg ttgtaaagaa tagcgtaccc actcgtctaa attatttaac aaaggcagtg
     2761 ctttttcgta aattcgtata tctacgtaag gattttctac gtccccgttg attttaaatt
     2821 ctgtaaacat tacaaacata tcgtaagaaa gcccagactc acttctacga ccaaagcgta
     2881 aagataagat tttttcataa gttgctttta aatcttctac aaatcgtaca tttgcagttg
     2941 ctttgtagtt acttaaatct tttagttggt caaacgtaaa acgaactgtc ttatcccctt
     3001 tttcacgcat tctagacacg atggaaaaaa acaaattcat ttcaaccggt gtaaattttc
     3061 ttaaaggaat tgtatttaat tcatggtggt attttacaat ctcattagcc atataatcac
     3121 ctcaatccaa ttatgaatga cattttttaa atgtcaagac attcatattt gacgttcaaa
     3181 cagacaaaat gtccttcata aacagacaaa atgtccttca taaacagaca aaatgtcctt
     3241 cataaacaga caaaatgtcc ttcataacat tctgtatcca ttggtagagt aaggacacag
     3301 cttacggtaa agaggtttaa aaagaggttt aaaaagagat ataaaaagag gggggctaat
     3361 tttcccgcct aaaaaccact tcttttttct ttaaacaggt tcgcgcattt ttcaaaactg
     3421 ccaatccaaa accttgcttc ctacggtcgc caaaaaggtg tgatcgctac gctctcacat
     3481 tgtactgcgc agtcgcctaa aggctccttt gctaaaaaca tgttggtaaa gaggcctttg
     3541 agcggttctg aatgcttatc taagccgttt taagacagtc ttggataaaa atccttatct
     3601 agctttaaag cgccttacag gcggtcaggg caagccctaa caaccctaaa ataagcgata
     3661 cttaaaaaca ccacacaagt ttaatttttt aagatataat aacttgtcgc ctatccgaca
     3721 gtcttgcgac tggaaggagg tgtatctaat gtttgaattg ttcatttgcc cccttcttat
     3781 agaagtttgt gtctctttat tcagttattg gttgaataac cgaaacaaga agtaaaatca
     3841 ataaaggcga catcaacctg aaaaaaagcc ccagagaatc cgacctctct ggggctttcg
     3901 tgtatctaat gtttgatcat ttgcatgttt agtttaacat gattgccgat caaattcaat
     3961 tttgctgttg ctgatctaac cattccttga cactttttag ataatttaat gccgtttctt
     4021 ttttcgttgg attttgtatg ttcgttgctt gctgaagcag tgctttataa cgttcgtagg
     4081 taactgattg ttgccgttct tttcgttcct gttcactagt tgaaaaaggg attgtatcac
     4141 tgaataaatt ataacaagct tcttctgtct gcgtatcttt aaaatattgc acgtcttttt
     4201 tggttcgctc atagttgtct tgaacctctt tttgctgttt ttctggcaag ttttgataaa
     4261 gacgagtgag tttttccatg tttttatccg tcaaacgttt ttcttgattc acaaaaatat
     4321 cgttcatttc ctcataacaa gtggtaaact cttccatttt ttgtgttaac acttgctcct
     4381 ttttcttttt atcacatgct gcttcatact tttgagtgat atcccctaat aaaatacttc
     4441 ttgaaatacg tttatttccc tctaaaacgc cgaataaacc acttaaaacg attgataatg
     4501 taaatataac ccctggcaat aaaaacctct taaatcgaat tttagagcct tttaatgaat
     4561 atcttgtttg ataagcctta tagctaagcc aaataattcc taaaatactg gcaaaaatga
     4621 gtagataggg taaatagaat gccatttcta tttattctcc ccataccagc caaaaggcta
     4681 acagtgtcat gattaagcaa cataaggggg caagaatatc cattgatcgc tgcataatta
     4741 cttttttctg ttctttattt cgctggttta atagcgcatg gtggaatttt ttgacttgtg
     4801 aatcaattgt agtttgtatt ctttctttgg tataaggtgc aagaaaagca cgttgtttct
     4861 ttatttcatt ttctatgtct tgtaacgttt tagaacgata attcttgttg gtagtctgct
     4921 cctctttcaa cgtgttggtc atggtttctt cgagtcggtc taatttccgg ttgttcagtc
     4981 gtaagagttc gttgttctct tcgtacttct tttgcagttt cgcgaatgct agctcgagct
     5041 cttcgtagct cgttggttcg ttgttgattg taggctcgtt ctcgtctgtc cagctcatgt
     5101 aaaatcgtct ccttttcgta atcctttcct agtttgttgg atcgtacttt tttctttttg
     5161 tggatcaatt cgtaagtaaa atttttccca cgattcaagc aatgaatgcc gaatgtttta
     5221 agagaatcac aaaattggtt atacgttcga gtttttttgt ttttcattgt ttgatcaatc
     5281 gcaaaccgaa tttcgtcttt ccaaacaggt tcattttttt cttttaattt gatttcagac
     5341 atggttcgtt tttcgggttt cttccctcgt tcagtgattg ttaagtcatg ttcaagacaa
     5401 atctcgtcat ttaggtcata acatttgttt aaaaatgctt gaccatgggc ttgaaatttg
     5461 ttcccagttt ccagattgac ggagttaatg acaatgtggt tatgaatatg gtctttgtct
     5521 gtatgtgtgt aaatcgcgat ttggtggtca ggggctattt ttttcgcata ctctgcccct
     5581 agttgattgg ctttttcagc ggtaatttct cctggtcgaa aagactggat caataagtgt
     5641 gcttgtacac gatcgtcttt tccatacagc atgcgaattt gtttcatttc gcttttggca
     5701 taatcaatgt cacagtttat ccctgttttg acggttgctc gtggttcggc gtaattgatc
     5761 gctcggctac aagaagtggt tcggcttact ttaactgttg ccatatcttt tgtagctcct
     5821 tttgcatgat ttttaggttt tcggataagc gttgggcgtc gccaggatca acgtcgtgtt
     5881 ggtgtgtgtt gcaccacttg gcaatttgat tgatattccc gccagctttg gctaaatcgc
     5941 gcgcgattgc ctgagcaatg tctggcgcca cttt
//
