LOCUS       NZ_CP138524.1          16729 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP138524.1 Klebsiella pneumoniae strain KP3813 plasmid pVIR3813,
            complete sequence.
ACCESSION   NZ_CP138524
VERSION     NZ_CP138524.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-06-07 14:29:43
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 177852
            Orig. end    :: 194581
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16729
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[14000:15782]"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      14001..15782
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
     cand_cluster    1..16729
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="IucA_IucC"
                     /kind="single"
                     /product="NI-siderophore"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..16729
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NI-siderophore"
                     /region_number="2"
                     /rules="IucA_IucC"
                     /tool="antismash"
     CDS             complement(641..1207)
                     /locus_tag="ctg1_201"
                     /transl_table=11
                     /translation="MIYYDNAFRLRIRHTSVYQIHQHLDFFMQERKGEKLPYSFKIFPG
                     TGDDSLLLVRTATALELPGEKKRELILSEGHEIKFITLMAIFHKGTKSEGRGRRQFAPS
                     EEASYQLALTKLAKAGFKPGQIVVSGPKFVHIDKGNAGRGFTLPVFTVQGTAIISNQQK
                     AEVGIVYGVGPKRVFGCGFMHLAGQ"
     CDS             complement(1319..2242)
                     /locus_tag="ctg1_202"
                     /transl_table=11
                     /translation="MAKQKFRITNWSTYNKALINRGSLTFWLDDEAIQAWYESATPSSR
                     GRPQRYSDLAITTVLVIKRVFRLTLRAAQGFIDSIFALMNVPLRCPDYTSVSKRAKSVN
                     VSFKTSTRGEIAHLVIDSTGLKVFGEGEWKVRKHGKERRRIWRKLHLAVDSNTHEVVCA
                     DLSLNNVTDSEAFPGLIRQTHRKIRAAAADGAYDTRLCHDEMRRKKISALIPPRKGAGY
                     WPGEYADRNRAVANQRLSGSNARWKWTTEYNRRSIAETAMYRMKQLLGDSLTLRDYDGQ
                     VAEAMAMVRALNRMTKAGMPESVRIA"
     CDS             2987..3814
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 167.1; E-value:
                     8.9e-51)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_203"
                     /transl_table=11
                     /translation="MKRNTVSNLTEKDDFDTLESILSVNIHSLLRPDGGTLLSDVHFAV
                     KAGECLAIIGPNGSGKTSLVRAISQELTHLKGDILLRGRSMSALSRQQRARLVAVLAQN
                     DTPDTRLSLEDYVALGRIPHAGDVPRNVHDAIVANAIKETGLQRLRRRSLLSLSGGERQ
                     RAALARVLAQTPDLVLLDEPTNHLDPPGREELLSLVKNKGIAVVAVLHDLTLTESFADR
                     VLLLSQGQSVICDTPEKVLVSEYLYPVFGLTSFTVPHPHTGKALRIFEVPHYV"
     CDS             3836..4792
                     /gene_functions="transport (smcogs) SMCOG1033:iron compound
                     ABC transporter, periplasmic (Score: 33.5; E-value:
                     3.4e-10)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_204"
                     /transl_table=11
                     /translation="MKKLFISLLSVLSASVASAADFPVTIESCGTPVTFSGPPKRAVIN
                     DLNMAEMAFALDLQDRIVGLTGISGWYKMTPEFKKAMGSIPELAPKYPTLETLLAAEPD
                     FFFAGWNYGMKVGGEVTPDTLSKYGIKTFVLSESCVFTTAHKNKATMDLLYNDILTLGK
                     IFGKRNDALSLVSGWQKRLSELPKPAAGTRPLKVFVYDSGEDKPFTSGKYAMPTAMIEA
                     AGGKNAMEALDTSWGTTSWESVAATEPDFIILLDYQTGSGADTLRHFLENHPLMKLTPA
                     VQHHRYLKLQYAELTPGPANVGAVEKLAWAMYPTEAK"
     CDS             4792..5796
                     /gene_functions="transport (smcogs) SMCOG1011:transport
                     system permease protein (Score: 265.6; E-value: 8.6e-81)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_205"
                     /transl_table=11
                     /translation="MLMSYRYHWVMWGSMVVLIGLMLFSITRGTVSLSLMQVLGALKIV
                     DEPVSAMVSRIVTDLRVPRMLLSVLTGAGLAMVGALLQTTTRNDLADPFLFGLSSGASA
                     GAVLVITRFGDRLGVLTLPVSAFVGGVCSAIAVMLLFHFKKQRGAEHLILCGLAISFLF
                     GALTSYFIFSGDQRAASSVLFWSLGGLGLATWNNLPFAVFSLVLLFAFVLLRWRSLDGV
                     LAGEQTALSLGINVSRLRIEIFLCCALATSLMVALTGVIGFVGLMVPHLCRHFAGVKHL
                     LLLPLCGVWGAILLCVGDIVSRTILAPQELPIGIITAGIGGLFIIMLLARNSP"
     CDS             6171..6539
                     /locus_tag="ctg1_206"
                     /transl_table=11
                     /translation="MENELDEVVRSKGYFWLASRPEFAGSWSQAGGIARQALGGMWWAS
                     VPKERWLEDAESLKFIMSNWIDGIGDARQELVFIGMDMNESKLRNRLDSALLTDAEMAE
                     GPQNWRHYPDPVEPWFEE"
     CDS             complement(6459..7166)
                     /locus_tag="ctg1_207"
                     /transl_table=11
                     /translation="MSNVDEGTKIYTPFTLKLYDWWVLSISNSYAWHCPTKEILLPYFL
                     QNLRPNHLDIGVGTGYYLAKAPANYNISLMDLNKASLKTASARIGKARIRYEVQHNVFE
                     SYPEELHGKFDSISMYYLLHCLPGAMVDKGVVIKNVKAALTKDGILYGATILGDGVMHN
                     SFSSKLMRIYNHKGIFSNMSDSEEGLKNGPFFALIRRHPTNTGAFDSFFEPRLNRIGIM
                     PPILRPFSHFCIR"
     CDS             complement(7621..8820)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1178:cobalamin synthesis protein/P47K family protein
                     (Score: 196.6; E-value: 1.1e-59)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_208"
                     /transl_table=11
                     /translation="MKRTPLIILNGFLGAGKTTLLKNLLTQAHKRRMAVSVIVNDMSEL
                     DVDGVLIANTEIVDAASNNFVSISADSISSRSGIQKLDSALKNLLEKRSPDFILLETSG
                     SSHPLPLVRYLREHPQVSLKAFLSLVDTVMLNDDYDGGKKLIPVFQEHLNRGTRGVESL
                     LAEQIMFCNKLLLTKNDRLPFYVVTEVARAIHPLNPQVAIMAVPWGNLQLDELLSMPDY
                     DFHRVALLIDELQDAIDAVLSDEPDKKYDISWRVIEDDRPFHPQRLWDTCHRFMGAGVY
                     RSKGFFWLPGRDDLALLWNQAAGSINLEFISYWKAGVLTHTDNSLTKEERAAIRQQLAK
                     MPGRFGDRRCRLTVIGESGEIDDFALALRQCLLTEEEILWWQQGGIFHDPWPTKVARLA
                     "
     CDS             8918..9304
                     /locus_tag="ctg1_209"
                     /transl_table=11
                     /translation="MATPVAKTYDWKQALRTHEQAPDRVTLYRILERLMQASIVQRYTD
                     SARTQRFALTLRATVGLFECDNCHHVIPIEREPTLEAAIGLVKSHLTGHGMTELWICLT
                     FLQTCGENKGIYDIPVVIYRKEFR"
     CDS             complement(9182..9502)
                     /locus_tag="ctg1_210"
                     /transl_table=11
                     /translation="MNDVHDFNVCSCDPVYHYVMSVCQNRPPRRAQPAYSEITIALWCS
                     ICAHTAKWGADALRRRENAGHLSELLAVDDHRYVINTFIFPTSLQKSQADPQLGHTMPS
                     EM"
     CDS             9541..9858
                     /locus_tag="ctg1_211"
                     /transl_table=11
                     /translation="MKSLFSSIVLLALSVPGGAMADEVTHTQYACDDSKTLDVVYIGDY
                     AVIQQMDELIPMKRAVSGSGMRYVPLNKDYIYELWGKGSNMNLSTYDGKKNEDILSNCK
                     P"
     CDS             complement(10408..10617)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275:peptide deformylase (Score: 56.8; E-value:
                     3e-17)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_212"
                     /transl_table=11
                     /translation="MPRAEKVKIRALNRYGKPFELEADGLLAICIQHEMDHLVGKLFMD
                     YLSPLKQQRIRQKVEKLDRLKDRA"
     CDS             complement(10758..10949)
                     /locus_tag="ctg1_213"
                     /transl_table=11
                     /translation="MSVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEEGI
                     AWLGILMLIYQTHDIRYY"
     CDS             complement(11133..11468)
                     /locus_tag="ctg1_214"
                     /transl_table=11
                     /translation="MVTIHKALDECSAKYPVFYEDEVDIHLNPKIGSDWQLRGQQKRVV
                     TLGQNEKYYLAGALHSGTGKVSYVGGNSKSSALFISLLKRLKATYRRAQAIRRTWTKPG
                     NAALVKV"
     CDS             complement(12410..12649)
                     /locus_tag="ctg1_215"
                     /transl_table=11
                     /translation="MGERYDKTQTVAALINEDVEVINAYSFQLALLTKDCALLTYRSEV
                     VDSKRRFVRQFGRGAIFVQIIRNVGSSDFTKGRQ"
     CDS             complement(12702..13901)
                     /locus_tag="ctg1_216"
                     /transl_table=11
                     /translation="MPQKTLSCWPLAFSAGLLGVGQNGLLVAIPVLVIQTNLSLSIWAA
                     LLMLGSMLFLPSSPWWGKQIARIGSKPVVLWALGGYGASFTLLGLGSMLMATGAVTTAV
                     GLGILIIARIAYGLTVSAMVPACQVWALQRAGEGNSMVALATISSGLSCGRLFGPLCAA
                     AMLAIHPLAPMGLLMAAPLLALVMLLRLPGTSPRPTAERKSASLRLDCLPYLLCALLLA
                     AAVSMMQLGLSPALTRQFATDTAAISHHVAWLLGLAAVAALIAQFGVLRPQRLTPMALL
                     LSAGALMICGLAIMFAEQLWLFYLGCAVLSFGAALATPAYQLLLNDKLTDGTGAGWIAT
                     SHTLGYGLCALLVPLVSKSGAAAAALIIAAFFVAVLFTIISIFIWFNLKFSTADRAVNG
                     "
     CDS             14001..15782
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_217"
                     /sec_met_domain="IucA_IucC (E-value: 4.8e-64, bitscore:
                     210.0, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGIFIDKILIIMTSEICLTMTLPTKTSTLDVAAQCFLNSLVRETK
                     DWRLTEYQPTQLIIPLGEQQALHFRVAYFSPTQHHRFEFPARLVTASGSHPVDFATLSR
                     LIVDKLQHQLLLPATSCETFHQRVMESHAHTQQAIDARHDWAALREKALNFGEAEQALL
                     VGHAFHPAPKSHEPFNQQEAERYLPDFAPHFPLRWFAVNKTQIAGESLHLNLQQRLTRF
                     AAENAPQLLNELSDNQWLFPLHPWQGEYLLQQEWCQELVAKGLIKDLGEAGAPWLPTTS
                     SRSLYCATSRDMIKFSLSVRLTNSVRTLSVKEVKRGMRLARLAQTDDWQTLQARFPTFR
                     VMQEDGWAGLRDLHGNIMQESLFALRENLLVDQPQSQTNVLVSLTQAAPDGGDSLLVAA
                     VKRLSDRLGITAQQAAHAWVDAYCHQVLKPLFTAEADYGLVLLAHQQNILVQMLGDLPV
                     GLIYRDCQGSAFMPHAAGWLDTIGEAQAENVFTREQLLRYFPYYLLVNSTFAVTAALGA
                     AGLDSEANLMARVRTLLAEMRDQVTHKTCLNYVLENPYWNVKGNFFCYLNDHNENTIVD
                     PSVIYFDFANPLLAQEG"
     CDS             15783..16727
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1203:putative siderophore biosynthesis protein (Score:
                     310.9; E-value: 2.4e-94)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_218"
                     /transl_table=11
                     /translation="MSKANIVHSGYGLRCEKLDKPLNLSWGLDNSAVLHWPGPLPTGWL
                     RDALEQIFIAAPQLSAVVLPWAEWREEPQALTLFGQVKSDIIHRTAFWQLPLWLSSPAN
                     RASGEMVFDAEREIYFPLRPPRPQGEVYRRYDPRVRKTLSFRVADPVLDAERFTRWMND
                     PRVEYFWEQSGSLEVQTAYLERQLTGKHAFPLIGCFDDRPFSYFEIYWAAEDRIGRHYS
                     WQPFDRGLHLLVGEQQWRGAHYVQSWLRGLTHYLLLDEPRTQRTVLEPRADNQRLFRHL
                     EPAGYRTIKEFDFPHKRSRMVMADRHHFFTEVGL"
ORIGIN
        1 atgaggtaca tattttcttt gtcaccgagg atgcggtgat tacacataca gtcgaccatt
       61 accatcgcat gggtcgtaac aataaagtta gcactgagag cattcaggcg aatatcatca
      121 atgtcctgta tatcatccca gatggagtag gtgaccatct ctggcgtgat ctgcgctggc
      181 agttcaccat actcttcttc aaactcaacc agaggttttg accagttagc gagtttttca
      241 aggaccttaa ccgtatccag atcggtaaat tcgtccatga gtaacagtcc acgtactttc
      301 tccagggata cgtaatttac tttccccata agccgggaaa aagtaacttt tatgccgcat
      361 tgttcagcta tctgttcaag gagaggacga tcgcttctga atatctggtg catcagtgca
      421 tgagaattcg tggcaatcac aaattttgcc tcagggtttt tcagcagaat cagaagcgcc
      481 ggtaccagat agcccagcgt ttttcctaca cctgtttcag cactaatcag tgcaacttta
      541 tgatcctgag tcagtgcacc agctgcagcc tcgatataat cctgttggac cttacgtaac
      601 gacaatccgg cagactcaaa taccgctgat gtattcatga ctactgcccc gccagatgca
      661 tgaaaccgca accaaatacg cgtttagggc ctacgccata aacgattccc acttcagctt
      721 tctgttgatt gctgattatg gcggtaccct gtaccgtgaa tacgggtagc gtaaaaccac
      781 gtccagcatt tcctttgtcg atatggacga atttcgggcc actgacgacg atttgaccgg
      841 gtttaaaccc agccttcgct aatttggtga gggccaactg ataactagcc tcttcagatg
      901 gagcaaactg gcgtcggcca cggccttctg actttgttcc tttatgaaag atggccatta
      961 acgtaatgaa cttgatttca tggccctcag agagaataag ctctcttttt ttctccccag
     1021 gcaactccag agctgtagct gtgcggacca ggagtaacga atcatccccg gtaccgggaa
     1081 aaattttaaa agagtacggc agcttctctc ccttacgttc ctgcatgaaa aaatccaggt
     1141 gctggtggat ctggtaaaca cttgtgtgac ggatacgcaa ccgaaacgca ttatcgtagt
     1201 aaatcatggt tatacctttt tcaagaggtg caaaatgctc aggcgttgat ggggatcagt
     1261 cggggctttg ttgaataaat aagatttcgt gcgaacgacc ctgtagctgg ctggattttc
     1321 aggcaatacg cacgctttct ggcatcccag cctttgtcat cctgttcaac gcacgcacca
     1381 tggccatagc ttccgctacc tgaccatcgt agtcacgcag cgtcagtgaa tctcccaaca
     1441 actgcttcat tctgtacatt gccgtttccg ctatcgagcg acggttatat tccgttgtcc
     1501 atttccaccg tgcattgctt ccgctcagcc gctgattagc aacggcacgg ttgcggtctg
     1561 cgtactcacc gggccagtaa cctgctcctt ttcggggagg aataagcgcg ctgatttttt
     1621 tgcggcgcat ttcatcgtga caaagccgtg tatcgtaagc cccgtctgcc gcggctgccc
     1681 tgatttttct gtgagtctgc cggataaggc ccgggaaggc ttctgagtcc gtgacgttat
     1741 tcagcgacag gtctgcacag acaacttcat gtgtgttgct gtcaacagca agatgcaact
     1801 ttcgccagat acgacggcgc tctttgccgt gctttctgac tttccattcg ccttcaccaa
     1861 agaccttcag cccggtggaa tcaatcacca ggtgtgcgat ttcaccccgg gtggacgttt
     1921 tgaaactgac attaaccgac tttgcccgct tactgacact ggtgtaatcc gggcagcgca
     1981 acggaacgtt catcagggca aaaatggaat caataaaacc ctgcgcagcc cgcagggtca
     2041 gccggaatac gcgtttaatc accagaacgg tggtgatggc gagatcagaa tagcgctggg
     2101 gccttcctcg tgatgaaggc gttgccgact cataccaggc ctgaatcgcc tcatcatcca
     2161 gccagaaagt gagggagcca cggttgatga gagctttgtt gtaagtggac cagttggtga
     2221 ttctgaactt ttgctttgcc acggaatggt ctgagttgtc gggaggatgc gtgatctgat
     2281 ccttcaactc agcaaaagtt cgatttattc aacaaagccc tttgacatgc acaattattg
     2341 tctgcccaat agtccgatag ttagcctgtt tacaaaaact gttgctggtc atactggtgc
     2401 tttattcccg gttaagcggg ctagttaacc cagagtgatg aaccatcctg gagtggcaga
     2461 taaagcagaa agaatggatt tgttgccctg attttttccg aatctaaata aagattagct
     2521 taatcactcg ttgttatgtt ataacattaa attagcaata ttctcagcca gcagcacggc
     2581 ctgtgggggg cggttattga gaacgaattc ggtgaaatct gtatagatga tgcattggtt
     2641 atcaatgcag atgaagaagt cttcgagatg aataatggct gcatctgctg cacggtgcga
     2701 ggagatttga ttcatatcct gagtcgtctg atgtaccgcc gcgataaatt tgaccgtatt
     2761 ctgatcgaat accaccggga tggccaatct actgagtgaa gcaaatgaag agagagccgc
     2821 taacgatcct gaatggtttt cttagtccta gtaaaaacat gcggttaaaa atttgttaat
     2881 gcagacacct caaccacaat ttcgatgtgc gtcatcgtga acgatttgag cggacaggat
     2941 gtcggcggcg tcctgattgc cagtatagaa atcaagaagg aacaccatga agcgcaatac
     3001 cgtaagtaat ctgacagaaa aagatgattt tgatacgctg gaaagtattc tcagcgttaa
     3061 tattcattct ctgttgcggc cagacggcgg gacgttgctt tctgacgtcc attttgcggt
     3121 caaagcagga gaatgtctgg ccattatcgg gcctaacggc agcggtaaaa cttccctcgt
     3181 gagagcgatt agtcaggaac tgacccatct aaagggggac attcttctgc ggggccgttc
     3241 tatgtctgct ttatcccgtc aacagcgagc ccggctggtt gctgttttgg cccagaatga
     3301 tacacctgat acgagattat cccttgagga ttatgtagcg ctggggcgta tccctcatgc
     3361 cggggatgta ccgcgtaatg tacatgacgc gattgtagca aatgccatta aagaaaccgg
     3421 attacaacgg ctacgcaggc ggtcactttt atcgctttcc ggcggcgaaa gacaacgagc
     3481 ggcgctggca cgggtactgg cacagacgcc cgacctggta ttgcttgatg aacccaccaa
     3541 tcatctcgat cctcccgggc gcgaggaact gctttccctt gtaaaaaaca aggggattgc
     3601 cgtcgtggcg gtgttgcacg atctgacact gacagaatca tttgctgacc gtgttctcct
     3661 cttgtcgcag gggcaatcag tgatctgtga cacaccggag aaggtattgg tatcagaata
     3721 cctttatccc gtttttggct tgaccagttt taccgtaccg catccccata caggaaaggc
     3781 gttgcgtatt tttgaagttc cgcattatgt ataaattact ttccgagagt cagtgatgaa
     3841 aaaattgttt atatccctgc tgtcggtact gtctgcttca gtagccagtg ctgccgattt
     3901 tcctgttact attgaaagtt gtgggactcc tgtaacattc tccggcccgc cgaaaagggc
     3961 tgtgatcaac gaccttaata tggcagagat ggcgtttgca ctggatttgc aggatcgtat
     4021 tgttgggctg accggtatta gtggctggta caaaatgacg ccggaattta aaaaggcgat
     4081 gggctcgatc cctgaactgg cacccaaata tcccaccctg gaaacattgc tggcagccga
     4141 gcctgatttc tttttcgctg gctggaacta tggaatgaaa gtaggcggcg aagtgacgcc
     4201 ggatacgtta agcaaatatg gcatcaagac tttcgttctg agtgaaagct gtgtgttcac
     4261 cactgcgcac aaaaataaag ccacgatgga tctgctgtat aacgatatcc tcacgctggg
     4321 taagattttt ggcaagcgca atgacgcact gtccctggtc agcggctggc aaaagaggct
     4381 gagtgaactg ccgaagccag cggcaggtac ccgtccttta aaggtgttcg tctacgactc
     4441 aggtgaggat aaaccgttta ccagtggtaa atatgcgatg cctacggcca tgattgaggc
     4501 ggctggtggt aaaaatgcaa tggaggcgct ggataccagt tggggaacga cgtcttggga
     4561 aagcgtggcc gctactgagc cggacttcat tattttgtta gattaccaga cgggcagcgg
     4621 tgcggataca ctgcgtcatt ttcttgagaa tcatccgtta atgaaactga ctccggctgt
     4681 tcagcatcat cgatacctga aattacaata tgctgaactg acgccgggac cagctaatgt
     4741 tggtgcggtg gaaaaactcg cgtgggcaat gtacccgaca gaagcgaagt gatgctcatg
     4801 tcgtaccgtt atcactgggt gatgtgggga tcgatggtcg tgctgattgg gttaatgtta
     4861 ttcagcataa ccagagggac agtctcactg tcgctaatgc aggtgctggg tgcactgaag
     4921 attgtggatg agccggtatc tgccatggtc agcagaattg tgacggattt acgcgtaccg
     4981 aggatgttgc tctctgtgct gacaggggcg ggactggcaa tggtaggggc attgttacaa
     5041 actaccaccc gtaacgatct ggctgatcct tttttattcg ggttatcctc cggtgcgtca
     5101 gcaggagcgg tgctggtgat cacccgtttt ggtgatcgac taggagtatt aacgctcccc
     5161 gtatcggcgt ttgttggtgg tgtgtgttcc gccatagcag taatgctgtt atttcatttt
     5221 aaaaagcaac gcggagctga gcatctaatt ctctgcggtc ttgccatctc ttttttgttc
     5281 ggggcgctga ctagttattt tattttttcg ggcgatcagc gagccgccag ctcagtgctt
     5341 ttctggtcac tgggtggcct gggattagcc acctggaata atttgccttt tgcagtgttc
     5401 agcctggtat tgctgtttgc ctttgtcctg ttgcggtggc gctctctgga tggtgtgctg
     5461 gcaggagaac aaacagcgtt gtcgctgggg attaacgtga gtcgtctgcg catcgagatt
     5521 tttctttgtt gtgcactggc aacatcgttg atggtggcat taaccggcgt gattggattt
     5581 gttggcttaa tggtgcctca tctgtgtcgg cattttgcag gagttaagca tctgttgttg
     5641 ttacctctgt gtggcgtctg gggtgcaata ttactgtgtg tcggcgatat agtcagccgg
     5701 acgatactgg caccacagga actaccaatt ggcattatta cggcgggcat tggagggttg
     5761 tttattatca tgttactcgc gcgaaactcg ccctagagaa tatgggcgat tactcgccgg
     5821 gcctcctgta attttcaagc gatgttatga aacgatggta atctaactga tggtttgagc
     5881 gtgccatgta agtaaagaag aactggcaaa ccttaatgtt gcattatatc ataacaaatg
     5941 ataagtgagg cccaatgttt ctcttactgg tcgtgctccc aagcatgcct ttggcgaaaa
     6001 ggttagacct caggctgcgt tcagcaacta catgatatct gtctggattg tgacggagat
     6061 gcggtactac tgcttgtggt tcaaaaaggt gaagcctgcc acacaagtcg gcggagttgt
     6121 ttttacaacg ctaccgccgg ccttttcatc cgacccgttt ctggcaggtg atggaaaatg
     6181 agctggatga agtcgtcaga tcaaaaggtt acttctggct ggccagccgt ccggaattcg
     6241 caggttcatg gtcacaggct ggtggcattg cgcgccaggc gctggggggc atgtggtggg
     6301 cgagtgtgcc gaaagaacgt tggctagagg atgctgagtc actgaagttc atcatgtcta
     6361 actggataga tggcattggt gatgcccgtc aggaactcgt ttttattgga atggatatga
     6421 atgaatcaaa actgcgcaac agactggatt ccgccctgtt aacggatgca gaaatggctg
     6481 aagggcctca aaattggcgg cattatcccg atcctgttga gccttggttc gaagaatgaa
     6541 tcgaaggcac ccgtatttgt cgggtgcctt cgtatgaggg cgaaaaaggg gccatttttt
     6601 agcccttctt cagaatcact catattagaa aaaatacctt tgtgattata aatcctcatt
     6661 agttttgatg agaaactatt atgcattacc ccatcgccaa gtatggttgc cccgtaaagt
     6721 attccgtcct tagttaaagc agctttcacg ttttttatga caacaccttt atccaccatc
     6781 gccccaggaa gacaatgtaa gagataatac attgatatag aatcgaattt accatgtagt
     6841 tcctctggat aagattcaaa tacattatgc tgaacttcat accgtattct ggctttccct
     6901 atccttgctg atgccgtttt caaactagcc ttattgagat ccataagtga gatattgtaa
     6961 tttgcaggag ctttggcaag ataataccca gttccaacgc caatatctaa atggttaggt
     7021 cttaaatttt gtaaaaaata agggagcaaa atctcttttg tcggacaatg ccaagcgtaa
     7081 ctgttggaaa tgctcagcac ccaccagtca taaagcttca aagtgaatgg tgtgtagatc
     7141 ttcgttcctt catcaacatt actcattagt tataccttgc aacagtcaat gtggataagc
     7201 agagcatata gcaatatgct caatatctcc tttctatttt atcacgattt tttccactac
     7261 ttaccaagat ttacaacaaa caacatatta ttgcaatgca ttgccatttt gttcacatac
     7321 ttggcaattt ataagtatat tgcataaata taaagttgac ttttagagtt cttttttgta
     7381 gataaactct catggaaata tggaaatatg gaaatatgga aatatggaaa tatggaaata
     7441 tggaaatatg gaaatatgga aatatggaaa tatggaaata tggaaatatg gaaatgaggt
     7501 aagaaacaga agactataaa atttgaagtc aaaaatggta actgagctcc tcctcgtttg
     7561 ggtgcttagg agatataact agtggagaat gaaatataac tattactgca aaataacctg
     7621 ttaagccagc cgggccactt tcgtgggcca gggatcgtgg aaaatccccc cctgctgcca
     7681 ccagagaatt tcctcttcag tgagtaaaca ctggcgcaat gcgagggcaa aatcgtcaat
     7741 ttcgccgctc tcgccaataa cagtcaggcg gcagcgccgg tcaccaaatc tgcccggcat
     7801 ttttgccagt tgctgacgga tagctgcgcg ttcttccttt gtcaatgaat tatcagtgtg
     7861 agtcaggacc ccggctttcc agtagcttat gaattcgaga ttgatgctcc ctgctgcctg
     7921 gttccacaat aatgccaggt catcccttcc cggtagccag aaaaaaccct tgctgcggta
     7981 aacgcctgcg cccatgaagc gatggcaggt atcccacagc cgctgcggat gaaatggacg
     8041 gtcatcctca atgacccgcc acgaaatatc atattttttg tcgggttcat ccgacaaaac
     8101 tgcatcaatt gcatcctgaa gctcatcgat aagtaacgcc acccgatgaa aatcgtaatc
     8161 cggcatggaa agcaattcat ccagctgtaa atttccccag ggcacggcca taattgcaac
     8221 ctgcggatta aggggatgta tggctctggc tacctcagta acaacataga agggtaatct
     8281 gtcgtttttg gttaacaaga gcttattaca gaacataatc tgttctgcca gcaggctttc
     8341 cactccccgg gtccctctgt tgaggtgctc ctggaaaacc ggaataagtt tctttccacc
     8401 gtcgtagtca tcattaagca tgaccgtatc tacaagcgac aaaaatgctt taagacttac
     8461 ctgggggtgt tctcgcagat agcggaccag gggaagagga tggctgctgc ctgacgtttc
     8521 cagtaaaata aaatccggag accgtttttc gagcaggttt ttcagcgcgg aatccagctt
     8581 ctggatccca cttctgctgc tgatactgtc tgctgaaata ctcacaaaat tgttactggc
     8641 tgcatcaacg atttctgtgt tggctatcag gacgccatcc acatcaagtt cactcatgtc
     8701 attaacgatg acggatacag ccattcgccg tttgtgtgcc tgtgtaagaa ggttttttag
     8761 cagagtagtt tttcctgctc ccagaaaacc attaaggata atgagcggtg ttcttttcat
     8821 agcatccagc cttatgccgc taaacgttaa tgcaatcaag ttgcaataat accggcttcc
     8881 tgccagaatt caaatgacat gactcggagg gggaaatatg gcaacaccag tagccaaaac
     8941 gtatgactgg aagcaagcgt tgcgcacaca tgagcaggct cccgatcgtg tgacccttta
     9001 ccgaatactg gagcggctaa tgcaggccag tattgtccag cgttataccg actcggcaag
     9061 aactcagcgt ttcgctctga ctctacgggc taccgtagga ctttttgaat gcgataactg
     9121 ccatcatgtt attcctattg agcgggagcc aaccctggaa gcggccattg gattggtaaa
     9181 gtcacatctc actgggcatg gtatgaccga gctgtggatc tgcttgactt ttctgcaaac
     9241 ttgtggggaa aataaaggta tttatgacat acctgtggtc atctaccgca aggagttccg
     9301 atagatggcc cgcattttct ctcctccgga gagcatcggc tccccacttg gctgtgtggg
     9361 cgcagataga acaccaaagc gcgatggtga tctcgctgta agcgggttgt gcgcgacgag
     9421 gaggtcgatt ttgacaaaca ctcatcacat agtgatatac agggtcacag ctgcacacat
     9481 tgaagtcgtg aacgtcgttc atgcccgccc tcagaataac gaaacaagga gaaaactttc
     9541 atgaaatctc tattttcctc tatcgttctg cttgctttga gcgtccccgg gggggctatg
     9601 gcagatgaag tcacccacac ccaatacgcc tgcgatgaca gcaaaacgct ggatgtggtc
     9661 tacatcgggg actatgctgt catccagcag atggatgagt tgatcccgat gaagcgggct
     9721 gttagtggtt caggcatgcg ctatgtgccg ctcaacaagg attacatcta cgagctgtgg
     9781 ggcaaaggca gcaacatgaa tctttccacc tatgatggta aaaagaacga agacatcctg
     9841 agcaactgca agccgtaagc attcaacgag acagcccgtc atagccacga ctgcggttcc
     9901 gatcacgccc tcggcccagc tctgattgtc tgtgggactg acctgcaaaa cagggggggg
     9961 ctgaaagatg tcctgatagc ctgagtggat ggactcattg gctttcctga agtagtcagt
    10021 gtgcggaagt ggatttccgt gtctcgttgt tgcacaaaca cgacaacgcc gaatagcttc
    10081 gcgttttatt agggcgaagc ttggaagaaa caccaactgc gccatgtctt tacccgcagc
    10141 caagatgccg atgcaaccca gcagatgcta cagttcaggc gtaacaaagc caccgttgga
    10201 tcgcatcaca gcgcgccgtt gcgataacgg ctcagcgtgg caatcacttc actcaaaggt
    10261 ttatcgctga agctcagaat gccctgcgac caagcggcgc tttcatcatc cactgaggct
    10321 attgcaccaa attcaggcgc gctaaactgc agactctcgc tttcaaggcc atgtaccaga
    10381 tcaaatcgcg actaatacat cttatcctta agcccggtct ttcagacgat ccagtttttc
    10441 aactttctga cgaatacgtt gttgtttcaa cggtgacaga taatccataa acagtttacc
    10501 aaccaagtga tccatctcat gctgaataca gatggctaac aagccgtctg cttccagttc
    10561 aaatggttta ccgtagcggt tcagggcgcg aattttcact ttctctgcgc gtggcactaa
    10621 agcacgttgt tcagggatcg acaggcaacc ttcttcaatg ctctagttct ttcgcgccga
    10681 gcgcttattt tctctaaaaa gctcggattc cggatgttca acaccaaccg ttcagtatca
    10741 cgttttactc cgaaacatca ataataacgg atatcgtgtg tttgatatat caacatgagg
    10801 attccgagcc aagcaatacc ttcttctgca tacatcgtct caaacatatc atcgacgata
    10861 cgctgaattt ctgcattcac ttcttctacc ggtttagcaa ctttgcgaag ccgctcgtcc
    10921 ggaatatgta acacttgcaa aactgacata aatctccaga gatatgttaa ggggttagaa
    10981 cgattatttt tctattctag acaaatccca ctctaattaa cagcattgta gtagtttact
    11041 gaatttgacc actgaacaga ggtgatgtgg tcgtctctgt tcaggtgcat caatgaaaac
    11101 aaagattatc taaatagctg cgccgaatac cgctacactt taaccagcgc tgcgtttccc
    11161 ggctttgtcc acgtccgcct gatggcttgc gcccgccgat acgtcgcttt aagccgcttc
    11221 agcaggctga tgaacagcgc cgaacttttg ctgttgccgc ctacatagct gactttacct
    11281 gttccgctgt gcagtgcgcc agccagataa tatttttcat tttgaccaag cgtcaccact
    11341 cgtttttgct gtccgcgcaa ctgccagtcc gaaccgattt tgggattaag atggatatcc
    11401 acctcatctt cataaaaaac cggatatttt gcgctgcatt cgtccagtgc tttgtggatt
    11461 gtcaccatct tttcatcctt atgcgggtca cggattcgca gagttggcgc ggccctgcgc
    11521 cacacaagct ccgcagaagg caaccagcgg cgaacggttc ctgcatgtaa ctggctgccg
    11581 gttatctcat tgattttgat tgccagaatt ttgtactcca gcgtgagcgc tggtagccaa
    11641 aatcgccggg agcatgtttt acaagctcac gtaattaagt ccttttgccc ccgctcgggg
    11701 ctttccggtt caggccggag ctggacgctt cggcattaac cctgacacaa accgaacagt
    11761 attgccttgt tctacgcatg gttgcgaaat agctacaaaa gtgagaatat taataataat
    11821 gaatatcatt ttcaatgttt gttcgcatgg tccacaccac aggcttcagc agcgacgtga
    11881 ctttgcagcc tttaccggcc agcacctgct gtactgcatt ttccggtacg cgggttgacc
    11941 cagcctgcat cgagaggagg ctggcaaacg ccacgcaggt tccgagatcg atctgcccat
    12001 gcaacccgcg tatacacttc cattgagcgt ggagccttat aaccgaccaa ggcctagatg
    12061 acttttctcg gttgccggta ttggcgacaa ctgtagtacc agatattatc catatcctga
    12121 ctggccttcg gtgtaagttt aacggttaag cgtattgggg taatttccag gttacgccct
    12181 ttcctctgta cggaggcatt acattgcctt tggtaattgg tgctgttgtg gaaggagttc
    12241 ctgctacttt ccagatacca ctttcagaac attttgtccg gtagttctgg tctgggaagt
    12301 cattccggtg atggtggtaa tccgaacagc ggttcgggct ggggtacaac acgaacacac
    12361 ctgtcttaat tcgccatctt gcgtgcctgc ccttcttcct gaacatcttt cactggcgtc
    12421 ccttggtgaa atctgagctg ccaacatttc tgatgatttg tacaaatatg gctcctctgc
    12481 caaattgacg aacgaagcgt ctttttgaat cgacaacctc gctgcggtac gtgagcaacg
    12541 cgcagtcctt ggttagtaaa gccaactgaa agctgtaagc attgatgacc tccacgtcct
    12601 cgttaattaa tgctgctacg gtctgcgttt tatcgtaacg ctctcccaca gtggcctatc
    12661 tccagagatt cgtcattgtc ctcttctaag catcaaccga tttagccatt aacagcccta
    12721 tcagctgttg aaaactttag attgaaccag atgaaaatag atattatggt aaataaaaca
    12781 gcaacgaaaa aagccgctat aatcagcgcc gcagcggcgg caccactttt cgacaccagc
    12841 ggcaccagca atgcacaaag cccatagcca agcgtatgac tggtagcaat ccagcccgca
    12901 cccgtgccgt ctgtcagttt atcattcagt agaagctgat aagcaggtgt tgccagagcc
    12961 gccccaaacg acagcaccgc acagccgagg taaaacaacc atagctgttc agcgaacatt
    13021 atcgccaggc cacaaatcat cagcgctccg gcactcaaaa gcagcgccat cggcgtcagg
    13081 cgctgcgggc ggagcacccc gaactgtgcg ataagcgcgg caactgcggc cagccctaac
    13141 agccacgcca catgatggct aatagcggcg gtatctgtag cgaactggcg agtaagggcg
    13201 ggagaaagac caagctgcat catgctcacc gccgcagcta ataacagcgc gcaaagcaga
    13261 taaggcaggc aatccagcct caggctggcg ctcttgcgct ccgctgtagg ccgcggtgac
    13321 gtgccaggca accgcagcag catcaccagc gccagcagtg gcgctgccat cagcagcccc
    13381 atcggcgcca gagggtgaat tgccagcatc gccgccgcgc acaacggccc gaatagtctg
    13441 ccgcagctca agccggagct aatggttgcc agagcgacca tgctattccc ttcccccgct
    13501 ctctgcaatg cccagacctg acaggctggt accatcgctg acacggtaag cccgtaggcg
    13561 atccgcgcga tgattaatat tcccagcccc accgctgttg ttacagcgcc ggtcgccatc
    13621 agcatgcttc ccagcccaag cagagtaaag cttgcaccgt atccccccag agcccacagc
    13681 accacaggct tactgccaat acgggcaatt tgctttcccc accacgggga agacggcagg
    13741 aacagcattg agccaagcat cagcaaagcc gcccaaatcg acaaactcag gtttgtctga
    13801 atcaccagta cagggatcgc gaccagcagg ccgttttgcc cgacaccgag taaccccgcg
    13861 ctgaacgcaa gcggccagca ggacaatgtt ttttgcggca tttccgcgct ctcaagagac
    13921 gtcacgatgt tgtaattcca tatattgatt gtgcttattt ataaaataaa ttttatcaat
    13981 cctaataatt tttgttgata atgggaatct ttatcgacaa aattctcatt atcatgacga
    14041 gtgagatctg tttgactatg actttgccaa ctaaaacctc aaccttggat gtggctgcgc
    14101 agtgcttcct taattccttg gttcgtgaaa ccaaagactg gcggctgacg gaataccagc
    14161 caacccaatt gatcatcccg ctgggcgaac agcaggcgct ccatttcaga gtggcttatt
    14221 tctccccaac ccagcatcac cgctttgaat ttccggcgcg tctggtcacg gcctccggca
    14281 gtcaccccgt cgatttcgcc accctctccc ggcttattgt tgataagctc cagcaccaac
    14341 tcttgctacc cgcgaccagt tgcgaaacct tccaccagcg cgtgatggaa agccacgccc
    14401 atacgcagca ggcaattgat gcccgccatg actgggcagc cctgcgtgaa aaagcgttga
    14461 actttggcga ggcggagcag gctctgctgg tcgggcacgc cttccacccg gcgcctaagt
    14521 ctcatgaacc gtttaaccag caggaggccg aacgctacct gccggacttc gcgccccact
    14581 tcccgctgcg gtggtttgcg gtgaacaaaa cgcagatcgc cggtgaaagc ctgcatctca
    14641 acctgcaaca acggttgacg cgatttgccg cagagaatgc gccgcagtta ctcaatgaat
    14701 taagcgacaa tcaatggcta ttcccgctgc acccgtggca gggggagtat ctgttgcagc
    14761 aggaatggtg ccaggagctt gtcgctaaag ggctgattaa agatttaggc gaggccggcg
    14821 cgccgtggct accgaccacc tcttcccgct cgctatactg cgccaccagc cgcgacatga
    14881 tcaaattctc cctgagcgtg cgcctgacca actccgtccg taccctgtca gtgaaagaag
    14941 tgaagcgtgg aatgcgcctg gcgcgcctgg cgcaaaccga cgactggcag acgctacagg
    15001 cccgcttccc gactttccgg gtgatgcagg aagacggttg ggccgggctg cgcgatctcc
    15061 acggcaacat catgcaggaa agcctgtttg ccctgcgtga aaacctgctg gtggatcagc
    15121 cgcaaagcca gactaacgta ctggtctccc tgacccaggc cgcgccggat ggcggtgatt
    15181 cgctgctggt tgcggcggta aaacgcctga gcgatcgcct cggcatcact gcgcaacagg
    15241 ccgcccacgc atgggtcgat gcttactgcc atcaggtgct gaagccgctg tttacggctg
    15301 aagcggatta cggcctggtg ctgctggcgc atcagcaaaa tattctggtt cagatgcttg
    15361 gggatctgcc ggtcgggctt atctaccgtg actgccaggg cagcgcgttt atgcctcacg
    15421 cggcaggctg gctcgacacc attggcgagg cgcaggcgga aaacgtcttc acccgtgagc
    15481 agttgctgcg ctacttccct tattacctgc tggttaactc cacttttgcc gtgaccgccg
    15541 cgctgggcgc tgccgggctg gacagtgaag cgaatctgat ggctcgcgta cgaacgttgc
    15601 tggctgaaat gcgtgatcag gtgactcata aaacctgtct caactacgtg ctggaaaatc
    15661 cgtactggaa cgtaaaaggt aactttttct gttatctgaa cgaccacaac gagaacacca
    15721 tcgtcgatcc ctcggtgatc tacttcgatt tcgccaaccc gctgctggct caggagggtt
    15781 aaatgtctaa ggcaaacatc gttcacagcg gatatggact gcgctgtgaa aaactcgaca
    15841 agcctctgaa tcttagctgg gggctggaca atagcgcggt gctgcactgg ccggggccgt
    15901 tgccgacagg gtggctgcgc gacgcgctgg agcagatatt tatcgccgca ccgcaacttt
    15961 cagcggtggt tctcccttgg gccgaatggc gtgaggagcc acaggcgctg acgcttttcg
    16021 ggcaggtaaa aagcgacatc atccatcgca ccgccttctg gcagttaccg ctatggctga
    16081 gttctccggc aaaccgggcc tccggcgaaa tggtttttga tgcagagcgt gagatttatt
    16141 tcccgctgcg cccaccccgt ccgcagggcg aggtttatcg ccgttacgat ccacgcgttc
    16201 gcaagacgct gagtttccgc gttgccgatc ccgttcttga tgcagaacgt ttcacccgct
    16261 ggatgaacga tccgcgcgtt gagtatttct gggagcaaag cggctcgctg gaggtacaga
    16321 ccgcctatct ggaacgccag ctcaccggta aacatgcgtt cccgctgatc ggctgcttcg
    16381 acgataggcc gtttagctat ttcgaaatct actgggcggc ggaagaccgc attggccgcc
    16441 actattcatg gcaacccttt gaccgtggcc tgcatctgct ggttggtgaa cagcaatggc
    16501 gcggagccca ctacgtacaa agctggctgc gagggctgac acattacctg ttgctggatg
    16561 agccccgcac gcagcgcacc gtactggagc cacgcgccga taaccagcgc ctgttccgcc
    16621 accttgagcc tgcgggatac cggacaatta aagagttcga cttcccacac aagcgctcgc
    16681 gcatggtgat ggcggatcgc catcacttct tcacggaggt cggtctgta
//
