LOCUS       NZ_CP133886.1          16942 bp    DNA              UNK 01-JAN-1980
DEFINITION  NZ_CP133886.1 Klebsiella pneumoniae strain AMR180026 isolate Human
            plasmid unnamed5, complete sequence.
ACCESSION   NZ_CP133886
VERSION     NZ_CP133886.1
KEYWORDS    .
SOURCE      .
  ORGANISM  .
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-06-07 16:34:02
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..6732
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[46:1732]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      47..1732
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..6732
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..6732
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             47..1732
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Cloacin"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1"
                     /sec_met_domain="Cloacin (E-value: 2.1e-110, bitscore:
                     357.5, seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGGDGRGPGNSGLGHNGGQASGNVNGTSGKGGPSSGGGTDPNSG
                     PGWGTTHTPNGDIHNYNPGEFGNGGSKPGGNGGNSGNHSGSSGGGQSSATAMAFGLPAL
                     ATPGAEGLALSVSGDALSAAVADVLAALKGPFKFGLWGIAIYGVLPSEIAKDDPKMMSK
                     IMTSLPADAVTETPASTLPLDQATVRVRQRVVDVVKDERQHIAVVAGRPMSVPVVDAKP
                     TKRPGVFSVSIPGLPSLQVSVPKGVPTAKAPPKGIVAEKGDSRPAGFTAGGNSREAVIR
                     FPKETGQKPVYVSVTDVLTPAQVKQRQEEEKRRQQAWDAAHPEEGLKRDYDKAKAELDA
                     EDKNIATLNSRIASTEKALPGARAAVQEADKKVKEAEANKDDFVTYNPPHEYGSGWQDQ
                     VRYLDKDIQNQNEKLKAAQASLNAMNESLSRDKAALTGAMESRKQKEKKAKDAENKLNE
                     EKNKPRKGTKDYGHDYHPVPKTEDIKGLGELKRGDPKTPKQGGGGKRARWYGDKKRKIY
                     EWDSQHGELEGYRASDGEHLGAFDPKTGKQVKGPDPKRNIKKYL"
     CDS             1742..1999
                     /locus_tag="ctg1_2"
                     /transl_table=11
                     /translation="MGLKLRLTWFDKKTEEFKGEEYSKDFGDDGSVIESLGMPLKDNIN
                     NGEFDLKKEWVPLLQPFFKNQIKPDVDNCYIAFDYRDGNW"
     CDS             2084..2233
                     /locus_tag="ctg1_3"
                     /transl_table=11
                     /translation="MKKVKTIFLFILIVAGFLLAACQANYIRDVQGGTVAPSSSSELTG
                     IAVQ"
     CDS             3716..5677
                     /locus_tag="ctg1_4"
                     /transl_table=11
                     /translation="MFNTDSLAWQWHIPELARQIYPWVSWLYREYYSLAGFFLVIGLFF
                     GLAELWAGRMRFVGLSHKERREYADRYKRDNNRTAPFSVLASLDSPGRMVRARRHVWNY
                     AYWLTGAAGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLV
                     AGVLLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNA
                     LADFSTEQARKQQAVFLGKDEQGQPVLVPRDTWRKTNIQILGLPGSGKSVMATNALIRC
                     VRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLV
                     AGFNLSETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLIT
                     KLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARD
                     EFRWWPHASIMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPADFV
                     KTTVLDNTPIRWFYRAASQESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQK
                     EARPLFDVNTLQHLPDGFAVMTGLGVARLAFSSPLRVDRREIPLKTFPVLAKTDPLAEY
                     QSEAGRQRPGDDDFAGLY"
     CDS             5677..6267
                     /locus_tag="ctg1_5"
                     /transl_table=11
                     /translation="MALERYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVAQRLGI
                     AAVQPVYRFLDSLVAKGLLVRAKYPVDGRQVSVWGLTPHGVAFSFDEDEPLTDIIPFQP
                     SRVSAAQLPHRLAVQSLRLAMEARGATGWRYLHRIALKGMKVPDALAELDGRTVAFEVE
                     RTVKSRRRYQEVVSGYRGLTLSGTKTHVKGFWS"
     CDS             complement(6362..7222)
                     /locus_tag="ctg1_6"
                     /transl_table=11
                     /translation="MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYI
                     ELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYS
                     PVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRW
                     EPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSA
                     LPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAS
                     LIKHW"
     CDS             complement(7405..7962)
                     /locus_tag="ctg1_7"
                     /transl_table=11
                     /translation="MRLFGYARVSTSQQSLDLQVRALKDAGVKANRIFTDKASGSSTDR
                     EGLDLLRMKVEEGDVILVKKLDRLGRDTADMIQLIKEFDAQGVAVRFIDDGISTDGDMG
                     QMVVTILSAVAQAERRRILERTNEGRQEAKLKGIKFGRRRTVDRNVVLTLHQKGTGATE
                     IAHQLSIARSTVYKILEDERAS"
     CDS             8126..11131
                     /locus_tag="ctg1_8"
                     /transl_table=11
                     /translation="MPVDFLTTEQTESYGRFTGEPDELQLARYFHLDEADKEFIGKSRG
                     DHNRLGIALQIGCVRFLGTFLTDMNHIPSGVRHFTARQLGIRDITVLAEYGQRENTRRE
                     HAALIRQHYQYREFAWPWTFRLTRLLYTRSWISNERPGLLFDLATGWLMQHRIILPGAT
                     TLTRLISEVREKATLRLWNKLALIPSAEQRSQLEMLLGPTDCSRLSLLESLKKGPVTIS
                     GPAFNEAIERWKTLNDFGLHAENLSTLPAVRLKNLARYAGMTSVFNIARMSPQKRMAVL
                     VAFVLAWETLALDDALDVLDAMLAVIIRDARKIGQKKRLRSLKDLDKSALALASACSYL
                     LKEETPDESIRAEVFSYIPRQKLAEIITLVREIARPSDDNFHEEMVEQYGRVRRFLPHL
                     LNTVKFSSAPAGVTTLNACDYLSREFSSRRQFFDDAPTEIISRSWKRLVINKEKHITRR
                     GYTLCFLSKLQDSLRRRDVYVTGSNRWGDPRARLLQGADWQANRIKVYRSLGHPTDPQE
                     AIKSLGHQLDSRYRQVAARLCENEAVELDVSGPKPRLTISPLASLDEPDSLKRLSKMIS
                     DLLPPVDLTELLLEINAHTGFADEFFHASEASARVDDLPVSISAVLMAEACNIGLEPLI
                     RSNVPALTRHRLNWTKANYLRAETITSANARLVDFQATLPLAQIWGGGEVASADGMRFV
                     TPVRTINAGPNRKYFGNNRGITWYNFVSDQYSGFHGIVIPGTLRDSIFVLEGLLEQETG
                     LNPTEIMTDTAGASELVFGLFWLLGYQFSPRLADAGASVFWRMDHDADYGVLNDIARGQ
                     SDPRKIVLQWDEMIRTAGSLKLGKVQVSVLVRSLLKSERPSGLTQAIIEVGRINKTLYL
                     LNYIDDEDYRRRILTQLNRGESRHAVARAICHGQKGEIRKRYTDGQEDQLGTLGLVTNA
                     VVLWNTIYMQAALDHLRAQGETLNDEDIARLSPLCHGHINMLGHYSFTLAELVTKGHLR
                     PLKEASEAENVA"
     CDS             11124..11363
                     /locus_tag="ctg1_9"
                     /transl_table=11
                     /translation="MLNVSFRSTERQTPYLFNRKANGIDEIWYICPDRPTLVRVQRAIL
                     AVDEIVNPQTGEARKTAELDRERLFACFKFMTTE"
     CDS             11370..11900
                     /locus_tag="ctg1_10"
                     /transl_table=11
                     /translation="MALYMVFIEDVEDKDGERCIMPTSEHLEDMAVMAWQTGAYVFRFE
                     DQAQHLAMMKFIGMYHERLNSDDKATYYFTGKNPAWEREKPAGMKLCDYLYRKVEQFAI
                     ENGVQVLDAGKYTPEQIGAMIDVVSERYGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRRWPFGKK"
     CDS             complement(11928..12107)
                     /locus_tag="ctg1_11"
                     /transl_table=11
                     /translation="MTKQEKTALNMAKFIKDQSLLLLEKLNELDMDTPADMCERLHEDA
                     ETLWQVMQDKLGEE"
     CDS             complement(12133..12561)
                     /locus_tag="ctg1_12"
                     /transl_table=11
                     /translation="MAKTLLNLSQAAQAAGITRRTLYNHVKQGKVTVSRDGKNNPVVDV
                     SELIRVYGNVNIPEKQIPGISHRENTQKNFPQEQLLAMQKELADLRQAVTLMLEDKTSR
                     EEERRQHDDERRKLQAEVDRLTTELTQKKKRFWSGWFS"
     CDS             complement(12725..13039)
                     /locus_tag="ctg1_13"
                     /transl_table=11
                     /translation="MPQVTISALAQRDLQRLQDFLKTKNRLAARKAGEVIVRAIQQLKT
                     LPDIGRPVPFLPLEYQELVIGFGDSGYVMLYRHDREMDRIVIVTVRHQKESGYPGADSL
                     "
     CDS             complement(13027..13305)
                     /locus_tag="ctg1_14"
                     /transl_table=11
                     /translation="MSSATSIRLDEELKDRLKTLADDRHRSAHALMLEAITEYIDREEK
                     RSQYLRDGQAAWQHYQETGLHLTAEEAEAWISTWGTENEQDAPPCHR"
     CDS             complement(13647..13865)
                     /locus_tag="ctg1_15"
                     /transl_table=11
                     /translation="MKAFTLTVLAAMFLTPVHAIPLKPVTTLQPTYPVQAAAKRIEGQV
                     TATFDILDDGRVDNVSLTGCHFFFGKR"
     CDS             complement(13862..14233)
                     /locus_tag="ctg1_16"
                     /transl_table=11
                     /translation="MRLIPFILLALCSPLLLTACKHSTTQPPKIYTLDKSSKISSYAAA
                     IKTAVEMQMFEPEAYAGKMCTVRISIQRDGTLNSAIAEGGDPKLCKAAISAVTHAKIPP
                     APDENTWQIFKNAPLDFRP"
     CDS             complement(14507..14752)
                     /locus_tag="ctg1_17"
                     /transl_table=11
                     /translation="MTHLKLTPAEEKRLADAFVAQALAMGLKGNRTLPKAVKQQVRERV
                     LRAIQDEREARRAQEMRREKYEAAETTFTWQPLRRR"
     CDS             15400..16884
                     /locus_tag="ctg1_18"
                     /transl_table=11
                     /translation="MYGEEKSDSLIVAAKQANNPKGAESVERRSGAKGNAEQPHMRRTQ
                     SRESMSQRLSRVREAAKQRKKERFTALFHLLTVEALEAAFLSLSRKAAAGVDGIRWMDY
                     AGNMKNNITDLHRRLHQGSYRAQPGRRHYIPKADGKQRPLGIASLEDKIVQYALVKILN
                     AVYENDFMGFSYGFRPGRSQHDALDALATGLVRTNVNWVLDADISQFFDRVSHEWLIRF
                     TEHRIGDRRVIRLIRKWLTAGTSEEGQWRATEEGTPQGAVISPLLANIYLHYVFDLWAH
                     QWRRRYATGNVVMVRYADDIVIGFDKRYDARRFRIAMQRRLREFGLTVHPEKTRLMEFG
                     RFAAENRAIRGKGKPETFNFLGFTHISGKDRNGRFMLIRKTRRDRMTATLKAIKDGLRR
                     RWHYSIPEQGKWLRRVVQGYLNYHSVPGNFPTMQKFRTHVTNLWRRALRRRSQKDDTTW
                     TKANKLAAAWLPRVRVLHPWPVERFTARHPRQEPGA"
ORIGIN
        1 atattggctt taatttattg ttttaaatgt caaagaggaa aacgatatga gtggtggaga
       61 cggtcgaggt ccgggtaatt caggtctggg acataatggt ggtcaggcca gtgggaatgt
      121 gaacggtacg tctggtaaag gtggcccttc atcaggtggt ggtacggatc caaacagcgg
      181 gccgggctgg ggtacgacgc atacgccgaa tggagatatt cataactata atccggggga
      241 gtttggtaac ggcgggagta aacccggtgg taatggtggt aacagcggca atcatagcgg
      301 tagctctggt ggcggacagt cttcggccac tgcgatggcc ttcggtctgc ctgccctggc
      361 tactccgggg gctgaaggac tggctttatc agtttccggc gatgcgttgt cggccgccgt
      421 tgctgatgtg ctggctgccc tgaaggggcc gtttaagttt ggtctgtggg ggattgcgat
      481 ctacggtgtg ctgccttctg agattgcaaa agatgatccg aaaatgatgt caaaaattat
      541 gacgtcatta ccggccgatg cggtgacgga gactccggca agtactttac cactggacca
      601 ggcgacggtt cgtgtcagac aacgggttgt ggatgtggtg aaggatgagc ggcagcatat
      661 tgcggttgtc gcaggtcggc caatgagtgt ccctgtggtg gatgcgaaac cgacaaaacg
      721 tccgggggta ttcagtgtgt cgattccggg tctcccgtct ctgcaggtga gcgtaccgaa
      781 aggtgttccg acagcgaaag ccccgccaaa aggcattgtt gctgaaaaag gtgattcacg
      841 tccggctggt tttacagccg gtggtaactc ccgtgaggcc gttattcgtt tcccgaaaga
      901 gaccggacag aagccggttt atgtgtcggt gacagatgtt cttaccccgg cacaggtaaa
      961 acagcgtcag gaggaagaaa agcgtcgcca gcaggcatgg gacgccgctc atccggaaga
     1021 ggggctgaaa agagactatg ataaagcgaa agctgagctg gatgccgaag ataaaaatat
     1081 tgcgacctta aacagccgca ttgcatcgac agagaaggcg ctccccggtg caagggctgc
     1141 tgttcaggaa gccgataaaa aggtaaaaga ggcagaggca aataaagatg attttgtgac
     1201 ttataacccg cctcatgaat atggctccgg gtggcaggat caggttcgct atcttgataa
     1261 ggatattcag aatcagaatg agaaattaaa agcggctcag gcatctttaa acgcaatgaa
     1321 tgaatcctta tccagagata aggctgcact taccggggcg atggagagcc ggaaacaaaa
     1381 ggagaaaaaa gcgaaggatg cagaaaataa gttaaatgag gaaaagaaca agcctcgcaa
     1441 ggggactaaa gactacggcc atgattatca tccagtacct aaaacagaag acataaaggg
     1501 acttggagag ttaaagcgag gtgatcctaa aacacctaaa caaggtggtg gtggtaagcg
     1561 ggcccgatgg tatggcgata aaaaacgtaa aatttatgaa tgggattccc agcacggtga
     1621 gcttgaaggg tatcgtgcca gtgatggcga acacctcggg gcatttgatc ccaaaacggg
     1681 taagcaggtt aaagggccag atccaaaacg gaacattaaa aaatatcttt gagaggtaaa
     1741 tatggggctt aaattacgtt tgacatggtt tgataagaaa actgaagagt ttaaagggga
     1801 agagtattct aaagactttg gtgacgatgg ttctgtcatt gaaagcttgg gaatgccttt
     1861 aaaggataat attaataatg gtgagtttga tttgaagaaa gaatgggttc ctttactaca
     1921 gccatttttt aaaaatcaaa taaaacctga tgtggataat tgttatatag cttttgatta
     1981 tcgggacggt aactggtaac aaaaaattat caaggatgat ttgaaatact gacttccggt
     2041 gttcagggat gaatgccgga gtctttaaat acagggaaag tatatgaaaa aggtaaagac
     2101 tatttttctt tttatattga ttgttgctgg ctttcttctg gccgcatgtc aggcaaatta
     2161 tatccgggat gttcagggcg gaacggtggc accatcgtcc tcctctgaac tgacggggat
     2221 cgcggttcag tagaaaagat caaaggatct tcttgagatc ctttttttct gcgcgtaatc
     2281 ttttgccctg taaacgaaaa aaccacctgg ggaggtggtt tgatcgaagg ttaagtcagt
     2341 tggggaactg cttaaccgtg gtaactggct ttcgcagagc acagcaacca aatctgtcct
     2401 tccagtgtag ccggactttg gcgcacactt caagagcaac ctcgtgttta gctaaacaaa
     2461 tcctctgcga actcccagtt accaatggct gctgccagtg gcgttttgcg tgctttcccg
     2521 ggttggactc aagtgaacag ttaccggata aggcgcagca gtcgggctga acggggagtt
     2581 cttgcttaca gcccagcttg gagcgaacga cctacaccgg gccgagatac cagtgtgtga
     2641 gctatgagaa agcgccacac ttcccgcaag ggagaacggc ggacaggtat ccggtaaacg
     2701 gcagggtcgg aacaggagag cgcaagaggg agcgacctac cggaaacggt ggggatcttt
     2761 aagtcctgtc gggtttcgcc cgtactgtca gattcatggt tgagcctcac ggctcccaca
     2821 gatgcaccga aaaagcgtct gtttatgtga actctggcag gagggcggag cctatggaaa
     2881 aacgccaccg gcgcggccct gccgttttgc ctcacatgct cgttccctgc ttatccacgg
     2941 aatctgtggg taactttgcg agagttcgca gcgcccgccg cagtctcacg gccggcgcgt
     3001 agcgaccgag tgagcgagga ggcgcaattt ccccggcacc tgcaagacgg tcaccggacg
     3061 cgtggatgtg acatattgct ccgtgttacc gcctttctct tccctgccga taaattattc
     3121 agataggtga agtctgtcgg ttttctgctg aatattttac gttaacctat ctctgttgct
     3181 tttttctcct tgcggagaaa tgcacgtcat ccccgctggg gcgtgactga cttcaggggg
     3241 aaatcccctg cttacgctgg ctggacgcca ccgacgcact gtctttcccc ctctttctgg
     3301 ctctgtccgg ctggacgccg gtcacgccag aaattcaccc ggcccccgtc aggctcacgc
     3361 ctgaccaccc acaaaatcca cggtgctgga cgcacctgac gaagcagcaa agctgctcct
     3421 gattttgcgg gtggtcagcc gctcgctatg gcgaactctg acgggggccg gaacaccgga
     3481 aaagaccgca ctggggtgcc gccttttcct ctcacacgct ggggcgtgct cgttgttcct
     3541 ccggggctgc gccttttccg catggggcgg aaagaggctg gcctccgcgg tgaaagctga
     3601 acgcaatcac cacggacgtg accgccgccg ccatgccttg gggcatgtcc gcggcttgtg
     3661 cagcaggggc tgcacaacac gccggtaaac ccgtcgtctg aaggagagag attgcatgtt
     3721 taatacggat tcgcttgcct ggcagtggca tatcccggag ctggcccggc agatttaccc
     3781 gtgggtcagc tggctgtacc gggagtatta cagtctggcc ggtttttttc tggttatcgg
     3841 cctgtttttc ggtctggcag aactctgggc cgggcggatg cgattcgtgg ggctgagtca
     3901 taaggagcgg cgggagtatg ccgatcgcta taagcgcgat aataaccgga ctgcgccatt
     3961 ttcggtgctg gcctcgctgg attcgcccgg gcggatggtc agggcacggc gacatgtctg
     4021 gaactacgca tactggctga ccggcgctgc cggtctggcc cttctggggg ggctggttgt
     4081 cgccgtgttt atcgagagct ggggagaaac cgtcctgcgt ccggacctct acgcgaacgc
     4141 agattattac ctgctgcagc cggctaacct gttcgggatt gcctggtgtg ccggaggtct
     4201 tgtcgcaggc gtcctcctgg cgcggctgct ggcgttcctg ctgcttgacg ggcattttgc
     4261 ggccgctgac gaggcggtga acgcgaaact gaatcaggag agccggcgca gcagccagcg
     4321 gaccggagaa atgaccgacg tccgccacct gcatttcggg gagccggtac cggttaacgc
     4381 gctggccgat ttttccacgg agcaggcccg gaaacagcag gcggtgtttc tgggtaagga
     4441 tgagcagggc cagccggtgc tggtcccgcg tgatacctgg cgcaagacca acattcagat
     4501 cctcggcctg cccgggagcg gcaagagcgt gatggccacc aacgcgctca ttcgctgcgt
     4561 acgcgatttc ggggacgcgg tggtgtactt cgacccgaaa ggggacgcgt gggcgccgca
     4621 cgtcttccgg gcgcactgcc cggacttcac cctgctggat ctgcggccgg ggaaaccggc
     4681 gcagctgaat ctgttccgcg atctcgacca gtacgccctg aagaatcttc tggttgccgg
     4741 atttaacctg agtgagaccg gcgacgtggc ggaccactac cgcatcagcg agcagaaagc
     4801 ggcgaagctg attgcggagc agtttccgca gggggcaaat attcagcagg tgctggcggc
     4861 ggcgtacgca ctgccggagg ccctgaaaaa ggacgtgaag gggctgatca ccaagctgga
     4921 gaacgtggcc gacctgagcg tccttcagac ggacagcggc atcgacgtgg cggggataat
     4981 caacggcggc ggctgcctgt acgtcatcgg ctcgatggac gatgaggcgg tgatccgggt
     5041 gcagaagatg ctgtttgccc gctgcgcgca aatcatcatt gcgcgggacg agttccggtg
     5101 gtggccgcac gcgagcatca tgctcgatga gattaaatat ctgctgtcga agtacgtgct
     5161 gaacgcgctg gggacgctgc gcagccggga ctgcaacctg ctgctcgcgc accagtcgct
     5221 gggcgacttc ggccagtgcg ggcaggatct gcccgctgat tttgtgaaaa ccacggtact
     5281 ggataacacg ccgatccgct ggttctaccg ggcggccagc caggagtccg ctcagtgggc
     5341 ggccggacag accggggaga tccgggtgga cgtggagcgc cgccgggcca gccgggaggc
     5401 ggggaacgtg gagcatatca gcggggacag cttcatccag aaggaggcgc ggccgctgtt
     5461 tgacgtgaac accctgcaac atctgcctga cgggttcgcg gtgatgaccg ggctgggcgt
     5521 ggcgcggctg gcgttcagca gcccgctgcg tgttgatcgc cgggaaattc cgctgaaaac
     5581 cttccctgtg ctggcgaaaa cggacccgct ggcggagtac cagtcggagg ccgggcggca
     5641 gcggccgggt gatgatgatt ttgcggggct gtactgatgg cactggagcg atacaacgtc
     5701 agccacgcga agcggcaggc acggaacgcg gagaaaacac ggctgaccct gcgctggctg
     5761 cgggaagaac tgtgttccac ggcggagctg gttgcgcaac ggctggggat tgcggcggta
     5821 cagccggttt accgcttcct ggacagcctg gtggcgaaag ggctgctggt ccgggcgaaa
     5881 tacccggttg acggccgtca ggtcagcgtg tgggggctga cgccgcacgg ggtggcgttc
     5941 tcgttcgacg aggacgagcc gctgacggac attattccgt ttcagccgtc gcgggtgtcg
     6001 gcggcgcagc tgccgcaccg gctggccgtg cagtccctgc gcctcgccat ggaggcccgg
     6061 ggggccaccg gctggcggta cctgcaccgt attgccctga aagggatgaa ggtgccggac
     6121 gcgctggcgg agctggacgg cagaacggtg gcgtttgagg tggaacgtac cgtcaagagc
     6181 cgtcgccggt atcaggaagt ggtgtccggg tatcggggtc tgacgctcag tggaacgaaa
     6241 actcacgtta agggattttg gtcatgagat tatcaaaaag gatcttcacc tagatccttt
     6301 taaattaaaa atgaagtttt aaatcaatct aaagtatata tgagtaaact tggtctgaca
     6361 gttaccaatg cttaatcagt gaggcaccta tctcagcgat ctgtctattt cgttcatcca
     6421 tagttgcctg actccccgtc gtgtagataa ctacgatacg ggagggctta ccatctggcc
     6481 ccagtgctgc aatgataccg cgagacccac gctcaccggc tccagattta tcagcaataa
     6541 accagccagc cggaagggcc gagcgcagaa gtggtcctgc aactttatcc gcctccatcc
     6601 agtctattaa ttgttgccgg gaagctagag taagtagttc gccagttaat agtttgcgca
     6661 acgttgttgc cattgctgca ggcatcgtgg tgtcacgctc gtcgtttggt atggcttcat
     6721 tcagctccgg ttcccaacga tcaaggcgag ttacatgatc ccccatgttg tgcaaaaaag
     6781 cggttagctc cttcggtcct ccgatcgttg tcagaagtaa gttggcagca gtgttatcac
     6841 tcatggttat ggcagcactg cataattctc ttactgtcat gccatccgta agatgctttt
     6901 ctgtgactgg tgagtactca accaagtcat tctgagaata gtgtatgcgg cgaccgagtt
     6961 gctcttgccc ggcgtcaaca cgggataata ccgcaccaca tagcagaact ttaaaagtgc
     7021 tcatcattgg aaaacgttct tcggggcgaa aactctcaag gatcttaccg ctgttgagat
     7081 ccagttcgat gtaacccact cgtgcaccca actgatcttc agcatctttt actttcacca
     7141 gcgtttctgg gtgagcaaaa acaggaaggc aaaatgccgc aaaaaaggga ataagggcga
     7201 cacgaaaatg ttgaatactc atactcttcc tttttcaata ttattgaagc atttaccagg
     7261 gttattgtct catgagcgga tacatatttg aatgtattta gaaaaataaa caaatagggg
     7321 ttccgcgcac atttccccga aaagtgccac ctgacgtcta agaaaccatt attatcatga
     7381 cattaaccta taaaaatagg cgtatcacga ggccctttcg tcttcaagaa ttttataaac
     7441 cgtggagcgg gcaatactga gctgatgagc aatttccgtt gcaccagtgc ccttctgatg
     7501 aagcgtcagc acgacgttcc tgtccacggt acgcctgcgg ccaaatttga ttcctttcag
     7561 ctttgcttcc tgtcggccct cattcgtgcg ttctaggatc ctccggcgtt cagcctgtgc
     7621 cacagccgac aggatggtga ccaccatttg ccccatatca ccgtcggtac tgatcccgtc
     7681 atcaatgaac cggactgcca cgccctgagc gtcaaattcc tttatcagtt ggatcatatc
     7741 ggcagtgtcg cggccaagac ggtcgagctt cttaaccaga atgacatcac cttcctccac
     7801 cttcatcctc agcaaatcca gcccttcccg gtctgttgaa ctgccggatg ccttatcggt
     7861 aaatatacgg tttgctttca cacctgcgtc tttgagtgct ctgacctgaa gatcaagaga
     7921 ctgctgactg gttgagaccc gagcgtaacc aaaaagtcgc ataaaaatgt accttaaatc
     7981 gaatatcgga caactcatgt ctattattac aaatttacga tttaatagac atattaatgt
     8041 aacagtttta cgatgtccga taatttataa catttcgtac ggttggaaaa atgttactaa
     8101 atgcccgtca ggcagggagg ccgatatgcc cgttgacttt ctgaccactg agcagactga
     8161 aagctatggc agattcaccg gtgaaccgga tgagcttcag ctggcacgat attttcacct
     8221 tgatgaagca gacaaggaat ttatcggaaa aagcagaggt gatcacaacc gtctgggcat
     8281 tgccctgcaa attggatgtg tccgttttct gggcaccttc ctcaccgata tgaatcatat
     8341 tccttccggc gtccggcatt ttaccgccag acagctcggg attcgtgata tcaccgttct
     8401 tgcagaatac ggtcagaggg aaaatacccg ccgtgagcat gcagcgctga tacgtcagca
     8461 ctatcagtat cgtgaatttg cctggccctg gacatttcgc cttacccgtc ttttatatac
     8521 ccggagctgg ataagcaacg aacgtcctgg cctgcttttc gatctggcga cagggtggct
     8581 tatgcaacat cgtattattc tccccggagc cactacgctg acccggttga tttcagaggt
     8641 aagggaaaag gcgacgttgc gcctgtggaa caaactggca ctgataccgt cagccgaaca
     8701 gcgttcacag ctggagatgc tgctggggcc aactgattgc agccgcctgt ctttactgga
     8761 atcactgaaa aagggccctg tgaccatcag tggtccggcg tttaatgaag caattgaacg
     8821 ctggaaaact ctgaacgatt ttggcctgca tgctgaaaac ctgagtacac tcccggctgt
     8881 gcgcctgaaa aatctcgcac gttatgctgg tatgacttcg gtgttcaata ttgccaggat
     8941 gtcaccgcag aaaaggatgg cggttctggt tgcctttgtc cttgcatggg aaacgctggc
     9001 gctggatgat gcattggacg ttctggacgc catgctggcc gttatcatcc gtgacgccag
     9061 aaagattggg cagaaaaaac ggctccgctc gctgaaggat ctggataaat ctgcattggc
     9121 gctcgccagc gcatgttcgt acctgctgaa agaagaaaca ccggacgaat cgattcgtgc
     9181 tgaggtgttc agctacatcc caaggcaaaa gctggctgaa atcatcacgc ttgtccgtga
     9241 aattgcccgg ccctcagacg ataattttca tgaagaaatg gtggagcagt acgggcgcgt
     9301 tcgtcgtttc ctgccccatc tgctgaatac cgttaaattt tcatccgcac ctgccggggt
     9361 taccactctg aatgcctgtg actacctcag ccgggagttc agctcacggc ggcagttttt
     9421 tgacgacgca ccaacggaaa ttatcagtcg gtcatggaaa cggctggtga ttaacaagga
     9481 aaaacatatc acccgcaggg gatacacgct ctgctttctc agtaaactgc aggatagtct
     9541 gaggcggagg gatgtctacg ttaccggcag taaccggtgg ggagatcctc gtgcaagatt
     9601 actacagggt gctgactggc aggcaaaccg gattaaggtt tatcgttctt tggggcaccc
     9661 gacagacccg caggaagcaa taaaatctct gggtcatcag cttgatagtc gttacagaca
     9721 ggttgctgca cgtctttgcg aaaatgaggc tgtcgaactc gatgtttctg gcccgaagcc
     9781 ccggttgaca atttctcccc tcgccagtct tgatgagccg gacagtctga aacgactgag
     9841 caaaatgatc agtgatctac tccctccggt ggatttaacg gagttgctgc tcgaaattaa
     9901 cgcccatacc ggatttgctg atgagttttt ccatgctagt gaagccagtg ccagagttga
     9961 tgatctgccc gtcagcatca gcgccgtgct gatggctgaa gcctgcaata tcggtctgga
    10021 accactgatc agatcaaatg ttcctgcact gacccgacac cggctgaact ggacaaaagc
    10081 gaactatctg cgggctgaaa ctatcaccag cgctaatgcc agactggttg attttcaggc
    10141 aacgctgcca ctggcacaga tatggggtgg aggagaagtg gcatctgcag atggaatgcg
    10201 ctttgttacg ccagtcagaa caatcaatgc cggaccgaac cgcaaatact ttggtaataa
    10261 cagagggatc acctggtaca actttgtgtc cgatcagtat tccggctttc atggcatcgt
    10321 tataccgggg acgctgaggg actctatctt tgtgctggaa ggtcttctgg aacaggagac
    10381 cgggctgaat ccaaccgaaa ttatgaccga tacagcaggt gccagcgaac ttgtctttgg
    10441 ccttttctgg ctgctgggat accagttttc tccacgcctg gctgatgccg gtgcttcggt
    10501 tttctggcga atggaccatg atgccgacta tggcgtgctg aatgatattg ccagagggca
    10561 atcagatccc cgaaaaatag tccttcagtg ggacgaaatg atccggaccg ctggctccct
    10621 gaagctgggc aaagtacagg tttcagtgct ggtccgttca ttgctgaaaa gtgaacgtcc
    10681 ttccggactg actcaggcaa tcattgaagt ggggcgcatc aacaaaacgc tgtatctgct
    10741 taattatatt gatgatgaag attaccgccg gcgcattctg acccagctta atcggggaga
    10801 aagtcgccat gccgttgcca gagccatctg tcacggtcaa aaaggtgaga taagaaaacg
    10861 atataccgac ggtcaggaag atcaactggg cacactgggg ctggtcacta acgccgtcgt
    10921 gttatggaac actatttata tgcaggcagc cctggatcat ctccgggcgc agggtgaaac
    10981 actgaatgat gaagatatcg cacgcctctc cccgctttgc cacggacata tcaatatgct
    11041 cggccattat tccttcacgc tggcagaact ggtgaccaaa ggacatctga gaccattaaa
    11101 agaggcgtca gaggcagaaa acgttgctta acgtgagttt tcgttccact gagcgtcaga
    11161 ccccgtatct gttcaaccgt aaggcgaacg gcatcgatga aatctggtac atctgccctg
    11221 accggccgac gcttgtccgg gtacagcggg cgattctggc ggtggatgaa atcgtgaacc
    11281 cgcagaccgg cgaggcccgc aaaacggcgg agctggaccg ggagaggctg ttcgcatgct
    11341 ttaaatttat gacaacggag tgagggatta tggcgctgta catggtattt attgaggacg
    11401 tggaagacaa agacggcgag cgctgcatta tgccaaccag cgagcatctg gaagacatgg
    11461 cggtcatggc ctggcagacc ggtgcatatg tattcaggtt tgaagatcag gcccagcatc
    11521 tggcaatgat gaagtttatc ggcatgtatc acgaacggct gaacagcgat gacaaagcca
    11581 cgtattactt caccggcaaa aatccggcgt gggaacgtga gaaaccggcc ggaatgaagc
    11641 tgtgtgatta tctttatcgc aaggttgagc agttcgccat cgagaacggc gtgcaggtac
    11701 tggacgccgg gaaatacacc ccggagcaga tcggggcgat gattgacgtc gtgagtgagc
    11761 ggtacgggga aagcgcggtg aacgagaagc tgaaagcgga gctgatgcgg gaatataaca
    11821 gccgctattt taacgttccg gtgccagaac tgccggagga taaacccgcc cgccggaggt
    11881 ggccgttcgg caaaaaataa acgccagcac cggccatgcc ggtgctgtta ttcttccccg
    11941 agcttatcct gcatcacctg ccagagtgtt tccgcatcct cgtgcagccg ctcgcacatg
    12001 tcggccgggg tatccatatc cagctcgttc agtttctcga gcaacagcag cgactggtcc
    12061 ttaatgaatt tagccatatt gagggcggtt ttttcctgct tcgtcatgtt ctccattccc
    12121 ttcggtaagt tctcagctaa accagccgga ccagaagcgt tttttcttct gtgtcagttc
    12181 tgttgtcaat ctgtccactt cggcctggag tttccggcgc tcatcatcgt gctggcggcg
    12241 ttcttcttct cgggatgttt tatcttccag catcagggtg acagcctgcc ggagatcggc
    12301 cagttccttt tgcattgcca gaagctgttc ctgtgggaaa tttttttgtg tattttcacg
    12361 gtgtgaaatg ccgggaattt gtttctcagg gatattcaca tttccgtata cacggatcag
    12421 ttctgacaca tccacgacag ggttgttttt cccgtcacgt gacacggtaa cctttccctg
    12481 ttttacatga ttgtatagcg ttcttctggt aatgcccgcg gcttgtgctg cctgtgaaag
    12541 gttgagcaat gttttcgcca ctgtataccc ctgattttat cgggtgtgaa agatgtgtaa
    12601 tttctcacgg taaatgtatc gctgaatttt acccgttttt ccgttcagga tgtggttttc
    12661 tgacgcgctg tgcttgtcaa accggcgacg gccacgcaat gaattgcgcc cccgtcatcg
    12721 gttattagag gctgtctgcc cccggatacc cggattcttt ctgatgcctg acggtgacga
    12781 tcacaatccg gtccatttcc cggtcgtggc ggtagagcat cacatagcca ctgtcgccaa
    12841 acccgatcac cagttcctga tattccagcg gcagaaatgg caccgggcgg ccaatgtctg
    12901 gcaatgtttt cagttgctgg atagcccgga cgatcacctc accggctttt ctggctgcca
    12961 gccgattttt ggttttgaga aagtcctgga ggcgttgtaa atctcgctgt gccagcgcgg
    13021 aaatcgttac ctgtggcatg gcggagcatc ctgctcgttc tcagttcccc aggtacttat
    13081 ccaggcttct gcttcttccg cagtaaggtg cagacccgtt tcctgatagt gctgccatgc
    13141 ggcttgtccg tcccgcaggt actggctgcg cttctcttcc cggtcgatgt attcggtgat
    13201 tgcctccagc attagcgcgt gcgctgagcg gtgccggtca tcggccagcg ttttcagccg
    13261 gtccttaagt tcttcatcga gcctgatgga tgttgctgat gacataaaag cccctttgta
    13321 gtcatgtgta atacatatga ctactttaat ccgtggcggc gctatttgcc agaaatacgg
    13381 cttttgctac ccatttttca gcttcgcttc cccatttttc agcttcgctt ccactaatca
    13441 gggctgctac aggctcactc atcatccagg actattgcag cctgcgggtt aaaggacctg
    13501 ttactggcgg caaccatcat cattgaactt tttggtggtg gctggtcgcg gatcctgtaa
    13561 gccgtcattt ttcagactga attcaaaatt tataacctgt cgcattgccg ggtgccctgc
    13621 gggatatagc cagtgcctca ttgccgtcag cgtttcccga aaaaaaagtg acagccggta
    13681 agcgacacgt tgtccactcg tccatcgtcc agaatatcaa acgtggcggt cacctgacct
    13741 tcgatgcgtt ttgctgcggc ctgtaccggg taggttggct gcagtgtggt tacgggtttt
    13801 agtggtatcg catgtaccgg agtgaggaac atggccgcca gcactgtcag agtaaaagct
    13861 ttcatggtct gaaatccaga ggggcgtttt tgaatatttg ccaggtattt tcatccggtg
    13921 ccggcggaat tttggcgtgg gtaacggctg atattgctgc tttacagagt ttcggatctc
    13981 ctccttcagc aatggcgctg ttcagagtgc catcacgttg tatggatatc cgcacggtgc
    14041 acatttttcc cgcataggcc tctggttcaa acatctgcat ttcaacagcg gtcttgatgg
    14101 ccgcagcgta gctactgatt ttagatgact tatccagagt ataaattttc ggcggctggg
    14161 tggtggaatg cttacaggcc gtcaggagta aggggctgca caatgccagc aggataaagg
    14221 gtattaaacg catcgggttg atgacctgtc agtaaaaaat attacatgta tatttgccac
    14281 tctttacggc cacgttcatt gacataaaca cggcttatcg tatcgttttt acaccaaacg
    14341 gcccgccatg cagttgcgtg cataggcatg cagcgggtta caatttaccg ggcgcgtttc
    14401 cggcggtttt ccgggtgatt tgttgcctgt tttatcccgt agccgccgga aacgctctga
    14461 gggcttctcg ggcggtgctg ataacgggtt ttatggtaaa tacccctcac cggcggcgca
    14521 gcggctgcca ggtgaaggtg gtttccgccg cctcgtattt ctcccgacgc atttcctgcg
    14581 cccgcctggc ttcacgttcg tcctgaatgg cgcgaagcac cctttcccgc acctgctgtt
    14641 ttaccgcctt tggcagcgtt ctgttccctt tcaggcccat ggccagtgcc tgagcgacaa
    14701 aggcgtccgc taggcgcttt tcttcagcgg gagtcagttt caggtgtgtc atggtggcct
    14761 ccgggcgtct caggtttcct gaacagttta accgcgggtc ctcccctcat accagttagc
    14821 tttcagatgt gtctatacca cctgaaatgt aagtgtgatg tacatctcaa ataataaaat
    14881 ttgttgccgt gagaaatttt cgggaaaaga cgcgatctgc ttacaggtgg ctccgggcgc
    14941 ttttttgtgc ctgaagatga gaactaatct catatattga cacctgaaaa cgggaggagt
    15001 aaggtaataa ttatactgtg tatatgtaca gtgtgcgccg ggagaccggt tagagatcaa
    15061 ggggtgaaag tccccgacca ttgaaggacc agcaatccac aaggtccccg agtcatgcgt
    15121 tgcataccgc gaggtatggg gcgaagcgtt gacaggggtg ttgacaggcc agccattgag
    15181 ccacgaaatg tatattaaat taccgggtgc cgacgttgta ctgttaacgg aaggcaacat
    15241 catagggtgc gatactgcga gtgccacatg gacccggcgg ggtctgagac cctggcatgt
    15301 caatacgatc tctacgcggg aaccgggaga tctcccctct gaccatctgc cagtgtcgga
    15361 gatggcccgc accgggaaga cgaggagtca tagccggtga tgtacggaga ggagaagtcg
    15421 gactcgctca tagtagcggc gaagcaggcg aacaacccga aaggagcgga gtcagtggag
    15481 cgaaggagcg gggccaaggg gaacgcggaa cagccacaca tgcgccggac acagagccgg
    15541 gaaagcatgt cacagaggct gtcacgcgtg cgggaagctg cgaagcagcg gaagaaagaa
    15601 cggtttacag cattgttcca cctgctgaca gtcgaagcac tggaagccgc attcctctcc
    15661 ctgagcagga aagcggccgc cggagtggat ggcatcaggt ggatggacta cgccggaaac
    15721 atgaagaaca acataacaga tctgcaccgg aggctacatc agggcagcta cagggcgcag
    15781 cccggcaggc gtcactacat cccaaaagcg gatggaaaac aacgcccgct cggcatcgcc
    15841 tcgctggagg acaagatcgt ccagtatgcg ctggtgaaaa tcctgaacgc agtctatgaa
    15901 aacgacttta tggggttctc atacgggttc agacccgggc gaagccagca cgatgcactg
    15961 gacgcactgg ccacagggct ggtacgcact aacgtaaact gggtactgga tgccgacatc
    16021 agtcagttct tcgacagggt gagccacgaa tggctgatca ggttcacaga gcatcggatc
    16081 ggcgaccgga gggtaatcag gctcatacgt aagtggctca cagccgggac gtcggaggag
    16141 ggtcaatggc gagcaacgga ggaaggcacc ccacagggtg cggtcatctc accgctgctg
    16201 gcaaacatat acctccacta cgtcttcgat ctgtgggcgc atcagtggcg acgtcgctat
    16261 gccacaggca atgtggtaat ggtcagatac gccgatgaca tcgtcatcgg gttcgacaaa
    16321 cgatacgatg cccggcgctt ccgtatagcc atgcagcgca gactgaggga gttcggactc
    16381 acggttcacc cggagaaaac ccgtctgatg gagttcggcc gcttcgctgc cgaaaaccgt
    16441 gccatcaggg gaaaaggcaa accagaaacg ttcaacttcc tcgggttcac gcacatcagc
    16501 gggaaagatc gcaacggcag gttcatgctg atacgaaaga cccgccggga tcggatgacg
    16561 gcaactctga aagccatcaa agacggtctg cgaaggcgct ggcattactc aatccccgaa
    16621 cagggaaaat ggctcaggag agtggttcag ggatacctga actatcactc ggtaccgggc
    16681 aacttcccca ccatgcagaa gttcaggaca cacgtaacaa acctctggcg ccgggcgctc
    16741 aggcgcagga gccagaagga tgatacgacc tggacgaaag caaacaaact ggcagccgca
    16801 tggctaccaa gggttcgggt tcttcatcca tggcctgtgg agcggttcac cgccagacac
    16861 ccgaggcagg agcccggtgc gtaaatcgcg cacgccggga tctgtgcggg gggtatccgg
    16921 taacgggtat ccctaccgcg ac
//
