LOCUS       NZ_CP129366.1          12160 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP129366.1 Staphylococcus epidermidis strain CKFA-393 plasmid
            pCKFA393-1, complete sequence.
ACCESSION   NZ_CP129366
VERSION     NZ_CP129366.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-06-07 23:35:11
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 13351
            Orig. end    :: 25511
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12160
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[5000:7160]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..7160
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..12160
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12160
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             10..684
                     /locus_tag="ctg1_14"
                     /transl_table=11
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TIYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDTEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVVTDQAPSTKAAMAKIIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
     CDS             992..1609
                     /locus_tag="ctg1_15"
                     /transl_table=11
                     /translation="MIQTIVTAAILYIATAVDLLVILLIFFARAKTKKEYRDIYIGQYV
                     GSVALIVVSLFFAFVLNYVPEKWILGLLGLIPIYLGIKVAIYDDCEGEKRAKKELNEKG
                     LSKLVGTVAIVTIASCGADNIGLFVPYFVTLSVTNLLITLFVFLILIFFLVFTAQKLSN
                     IPGVGEIVEKFSRWIMAVIYIALGLFIIIENDTIQTILGFIF"
     CDS             1628..1975
                     /locus_tag="ctg1_16"
                     /transl_table=11
                     /translation="MSYENACDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKISVASTSHHLRLLYKNDVLDFYKKGKMAYYFIKDDEI
                     KEFFSKNQEGF"
     CDS             2359..2544
                     /locus_tag="ctg1_17"
                     /transl_table=11
                     /translation="MQNTYIKKWVSLSSIISYSIEIFKCLYSEFSFPLNDVLLEGTDKK
                     ASKEYINKNQKTFYCL"
     CDS             2627..2848
                     /locus_tag="ctg1_18"
                     /transl_table=11
                     /translation="MAKYWKENQEGLLNDGEALTILMMLYNEHPYVVQLPCLNKQLQDD
                     NRYAQPTYTIYSTTKNRKENKRRIKNSI"
     CDS             3404..4375
                     /gene_functions="other (smcogs) SMCOG1237:transposase
                     (Score: 174.7; E-value: 5.9e-53)"
                     /gene_kind="other"
                     /locus_tag="ctg1_19"
                     /transl_table=11
                     /translation="MNPLEAKFKTSALRSWKTDQADAHKLACLGPTLKQTGSLPIHELI
                     FFELRERVRFHLEIENEQNRLKFQILELLHQTFPGLERLFSSRYSIIALNIAEIFTHPD
                     MVLDIDKEVLITHIFNSTDKGMSMDKATKYALQLRVIAQESYPNVDRHSFLVEKLRLLI
                     QQLKQSIHHLKQLDDAMIQLAQQLDYFENIHSIPGIGKLSTAMIIGEIGDIKRFKSNKQ
                     LNAFVGIDIKRYQSGHTHCRDTINKRGNKKARKLLFWVIMNIIRGQHHYDNHVVDYYYK
                     LRKQPNEKPHKTAIIACINRLLKTIHYLVMNHKLYDYQMSPH"
     CDS             complement(4531..4680)
                     /locus_tag="ctg1_20"
                     /transl_table=11
                     /translation="MKTLNEKQLKDINGGKGIVGEVTGEVTSIGNAISNGWHDLKQSVA
                     DTTK"
     CDS             complement(4701..4844)
                     /locus_tag="ctg1_21"
                     /transl_table=11
                     /translation="METLNEKQLKDINGGRETGCSGDFVEDGIMCNIGQGIGKAINKVR
                     GK"
     CDS             complement(5001..7160)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="resistance (resist) ABC_efflux (Score:
                     251.8; E-value: 8.1e-77)"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 283.5; E-value:
                     5.8e-86)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_22"
                     /sec_met_domain="Peptidase_C39 (E-value: 3.6e-40, bitscore:
                     128.0, seeds: 36, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR01193 (E-value: 7e-190, bitscore:
                     623.9, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMAIKFIRQYDEKDCGPTCLAMISQFYGKRVSIPRLREYAKTDKL
                     GTNLYGLVQAGKKIGIELTGVKADSFDDLKQAQLPVMVHIINQQGYDHYIIIEKIKNNT
                     LYIVDPAKGKYKLSSTEFGKYWTNIAVLIDKTDDFTTDNESPSYLNIFIDIFKNNYGKL
                     LFIAFISLFINIVGIVGALYFKLLTDHIIPSNVLKNLHIISFGILLLYIINALINYLRF
                     QLILHLSLKIDVNLMKDYFYHVLHLPMNFFDTRKSGEILQRFMDTSKIREALSSSTVTL
                     LVDTFMIIIGAILLYMQSPLLLLITIIFIPCFIICSYTLRKPFEKYNQKVAEKDAELSS
                     YLIESFDGSNTIKSYQSEDDRFYIGTTKFNGIIENLLKLGRFSNIQLTVNNFLKLTISL
                     VILWLGSYLVMTDSMTLGSLLAFNALTIYYLDPIERLINIQPTLQSSFVAARRIAEITD
                     LETETELYTSKQPYTFKNNIRIENVNFQYGFRSVVLKDINLNIKKGQKVAIVGESGSGK
                     STIGKLLNRYYTASEGNIMIDNYIIDDIDLSDLRKNIGYVSQNTFLFADTIKNNLLHGS
                     NKYKSDEDIVKACQLAESLDFIQKFPDQFNTMLEKEGANLSGGQGQRLSLARTFLKDPD
                     IYIFDEATSALDSLTENKIMEHIDLLTQHGKTVIIISHKLSTIKNADNIYVLNEGQIAE
                     NGTHDELIHLNGIYKNLWQLQMKID"
     CDS             7385..7993
                     /locus_tag="ctg1_23"
                     /transl_table=11
                     /translation="MIIGYARVSSVDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEVINTVNYLKDKEVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIVQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRI
                     IYHRVVEMLEEGKAISKIAKEVNITRQTVYRIKNGKGLS"
     CDS             complement(8245..8919)
                     /locus_tag="ctg1_24"
                     /transl_table=11
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYALSYRDISEILRERGVNVHHS
                     TVYRWVQEYAPILYRIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDIWL
                     RKQRDNHSAYAFIKRLIKQFGKPQKVITDQSPSTKVAMAKVIKAFKLKPDCHCTSKYLN
                     NLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIML
                     AS"
     CDS             8935..9507
                     /gene_functions="other (smcogs) SMCOG1130:transposase
                     (Score: 161.3; E-value: 4.6e-49)"
                     /gene_kind="other"
                     /locus_tag="ctg1_25"
                     /transl_table=11
                     /translation="MLKLYYKFNFATEPFFEYLKERGLQGTELVISDAHKGLVSAIRKS
                     FTNVSWQRCQVHFLRNIFTTIPKKNSKSFREAVKGIFKFTDINLAREAKNRLIHDYIDQ
                     PKYSKACASLDDGFEDAFQYTVQGNSHNRLKSTNLIERLNQEVRRREKIIRIFPNQTSA
                     NRLIGAVLMDLHDEWIYSSRKYINFDK"
     CDS             9510..9956
                     /locus_tag="ctg1_26"
                     /transl_table=11
                     /translation="MVKTLYSILHRSLDLTEFMEEVLIDDNMVFDIDNLKGFLNDTSSF
                     GFIAKENNKIIGFAYCYTLLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEI
                     GCSEMFLITDKGNPRACHVYEKLGGKNDYKDEIVYVYDYEKGDK"
     CDS             9957..11396
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_functions="resistance (resist) APH3 (Score: 59.1;
                     E-value: 3e-18)"
                     /gene_kind="other"
                     /locus_tag="ctg1_27"
                     /sec_met_domain="APH (E-value: 2.6e-26, bitscore: 84.1,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYGGRDKKYTLES
                     LKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFIGE
                     PNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLPEHE
                     LHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYLVNNE
                     YIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKEIKGTF
                     LTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYILLRETIY
                     NDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGIIDFGDSGI
                     IDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPIETIVYGIK
                     NIKQEFIENGRKEIYKRTYKD"
ORIGIN
        1 gtcttctgta tgaactattt cagatataaa caatttaaca aggatgttat cactgtagcc
       61 gttggctact atctaagata tgcattgagc tatcgtgata tatctgaaat attaagagaa
      121 cgtggtgtaa acgttcatca ttcaacgatc taccgttggg ttcaagaata tgccccaatt
      181 ttatatcaaa tttggaagaa aaagcataaa aaagcttatt acaaatggcg tattgatgag
      241 acgtatatca aaataaaagg aaaatggagc tatttatatc gtgccattga tacagaggga
      301 catacattag atatttggtt gcgtaagcaa cgagataatc attcagcata tgcgtttatc
      361 aaacgtctca ttaaacaatt tggtaagcct caaaaggtag ttacagatca ggcaccttca
      421 acgaaggcag caatggctaa aataattaaa gcttttaaac ttaaacctga ctgtcattgt
      481 acatcgaaat atctgaataa cctcattgag caagatcacc gtcatattaa agtaagaaag
      541 acaagatatc aaagtatcaa tacggcaaag aatactttaa aaggtattga atgtatttac
      601 gctctatata aaaagaaccg taggtctctt cagatctacg gattttcccc atgccacgaa
      661 attagcatca tgctagcaag ttaaacgaac actgacatga tatattagtg attagctata
      721 ttttttactt tgcaacagaa ccaaaagtat tttaattata acacggcatt tatgccgaga
      781 aaatttattg tgcgttgaga agaaccctta actaaacttg gagacgaatg tcggcatagc
      841 gtgagctatt aagccgacca ttcgacaagt tttgggattg ttaagggttc cgaggctcaa
      901 cgtcaataaa gcaattggaa taaagcatct atgattattt gaaaacataa gttataatac
      961 attcaaaaat atttttgaat gaggtgtaat tatgattcag actattgtaa ctgctgctat
     1021 tctttatatt gcgacagcag tagatttatt agtgatttta ttaatatttt ttgctagagc
     1081 aaagactaag aaagaatatc gagatattta tattggtcaa tatgtaggat ctgtggcatt
     1141 gattgtcgta agtttattct ttgcctttgt cttaaattat gttcctgaaa aatggatatt
     1201 aggattatta gggttaatac cgatttattt aggaattaaa gtagctattt atgatgattg
     1261 tgaaggagaa aagagagcta aaaaagaatt gaatgaaaaa ggattgtcta aattagttgg
     1321 tacggttgca attgttacga tagcaagttg tggtgctgat aatattggtt tatttgttcc
     1381 gtattttgtg acattaagtg ttactaattt attaattact ctgtttgtct ttttaatttt
     1441 aattttcttc ttggtattta ctgcacaaaa attatctaat attccaggag ttggagaaat
     1501 tgttgagaaa tttagtcgtt ggattatggc tgttatttat atagctttag gtttatttat
     1561 tattattgaa aatgatacta ttcaaacaat tttaggattt atattttaat ttagggtgcg
     1621 attttatatg agttatgaaa atgcttgtga tgtgatctgt gtacatgagg ataaagttaa
     1681 caatgcttta agttttttag aagatgataa atctaagaaa ttacttaaca ttttagaaaa
     1741 aatttgtgat gagaagaaat tgaaaatcat attatctttg attaaagaag atgagttgtg
     1801 tgtttgtgat atttctttga tattgaaaat aagtgttgct tcaacttcac atcatttaag
     1861 acttttatat aaaaatgatg tacttgattt ttataaaaag ggaaagatgg catattattt
     1921 tattaaagac gatgaaataa aagaattttt ctctaaaaat caggagggtt tttgaaacga
     1981 gtgaaacgag tttcttcttg tcttgatact ataaaaaagc aaagatataa cataaaatga
     2041 cttatcggaa gttatctatt atcccttatt cagagatgat ataatataca ggtcgcctat
     2101 ctctcaggcg tcaatttaga cgcagagagg aggtgcatat cagatggtcg aagctcttgt
     2161 tcacatcacg accacagtca tcagtggttg tattgttgcg ttatttacgc attggctacg
     2221 tacacgtaac aataagaaaa aataggcgat attagccaac acctaaaaat cccctcacta
     2281 ttgcgagtag tgaggggatt ggtgcatata atgtacgaag ctcttgttgt ctaaattata
     2341 acactggtta gtagaagaat gcaaaacact tatattaaaa aatgggtatc tttgagtagt
     2401 atcataagtt atagtataga aatatttaag tgtttgtatt cagaatttag ttttccgtta
     2461 aatgatgtat tgctagaagg tactgataaa aaagcgagta aagaatatat aaacaagaat
     2521 caaaaaactt tttattgtct ataatcatct attactttct ttttactagt aacttcgata
     2581 attgcaaaca gtatcattgg ttattaaaaa aataaaagat gcaaaaatgg ctaaatattg
     2641 gaaagaaaat caagagggat tattaaatga tggggaagca ttaactatat taatgatgtt
     2701 atataatgag catccatatg tagtacaatt accgtgttta aataagcaac tacaagatga
     2761 caacagatac gctcaaccca cgtatactat atattctaca accaaaaaca gaaaagagaa
     2821 taaaagaaga ataaaaaata gcatataacc ttaataagat aattaatttt gttatattaa
     2881 aataatatat agataattta attatttaaa gtcgaacaat taaaacatac taagattagc
     2941 tatgaagaaa tctatgacga tagatttttt catagctatt ttttatagtt atagagagga
     3001 gtagactgtc cagactcttg gattttaaat ccgtataaaa aacaagtcag ctttactctc
     3061 gccttttgaa attcgtttgt agtatgttgg gttcttgaaa ccgtgtatag gaaaatgaaa
     3121 tgagaaaggt taagtaaagt ttttagcttc tcaattattc aaaggaggtt tttttatcga
     3181 ttacttaggt gttgatatta gtaaaagaag tagtgtagtt gcacattata aaaatggaaa
     3241 attccaaaaa gagtttttca tccaaaataa taaaaatggt tacaattatt tactcaagta
     3301 tttgaatgac ttacaccacc cacaactcat ttttgaatct acaggtatct attcaagagg
     3361 tatggaacga ttttgttgtg taaatcaaat taactatatt caaatgaatc cgttagaagc
     3421 caaatttaaa acgagcgctc taagatcatg gaaaactgat caggcagatg ctcataagct
     3481 tgcttgttta ggaccgacgc ttaaacaaac aggcagctta cctatacatg agttaatatt
     3541 ctttgaatta agagaacgcg tccgttttca tctagaaatc gagaatgaac aaaatcgact
     3601 taaatttcag atccttgaat tactccatca aacattccct ggtttagaaa gattatttag
     3661 tagtcgatat tcaatcattg cactcaacat cgcagaaatc tttactcatc cagacatggt
     3721 tcttgatatc gacaaggagg tactgattac acatatattc aattctacag ataagggaat
     3781 gtcaatggat aaagctacaa aatatgcact tcaattaagg gtgattgctc aagaaagcta
     3841 tcctaatgtc gatagacatt cctttctagt cgaaaaatta cgcttactta ttcaacaatt
     3901 aaaacaatct attcatcatc tcaaacaatt agatgatgcc atgattcaat tagcacaaca
     3961 actcgattat tttgaaaata ttcattcgat acctggtatt ggtaagctaa gcacagctat
     4021 gattattggg gagattggtg atattaagcg atttaaatca aataaacaac tcaatgcttt
     4081 tgttggcatt gatatcaaac gatatcaatc aggtcataca cactgtagag ataccatcaa
     4141 caagcgtggt aataaaaaag cgagaaaact tttattttgg gtgattatga atataataag
     4201 agggcagcat cattatgaca atcatgtcgt cgattattac tacaaactaa gaaagcagcc
     4261 taatgagaaa cctcataaga ctgccatcat tgcttgtata aatcgattat taaaaacaat
     4321 tcattatctt gtaatgaatc ataaattgta cgattatcaa atgtcaccac attagccaaa
     4381 cgtacaatca aatgtagttt aacaccttat tcaaaaaaat taaaatgaac ggtttagtta
     4441 agtaatgctt attttaatta taagtacttg actaatcgta ggaaaaagtc tgggttatta
     4501 cccagacttt tttaatttaa ataatgagtc ctattttgta gtatcagcga cagactgttt
     4561 taaatcatgc caaccatttg aaatggcatt accaatacta gtgacttcgc cagtgacttc
     4621 accaacaatc cctttaccac cattgatatc ttttaattgt ttttcattta gtgttttcat
     4681 tgaaatagtc ctcctttaaa ttattttcct cgtactttat taattgcttt accaatacct
     4741 tgtccgatat tgcacattat tccatcttct acaaaatcac cagaacaacc agtttcacga
     4801 ccaccattga tatcttttaa ttgtttttca tttagtgttt ccattgaaat agtcctcctt
     4861 taagtaattt catcttacat cttataaatt agcatttgaa tataaagaga atgtaaatag
     4921 acagttaagt gagctttttt ttgagtttat tttttttatt atcgaaatat atttaataaa
     4981 tagagtatat taatataaaa tcagtctatt ttcatttgaa gttgccataa atttttatat
     5041 ataccgttta aatgaatcaa ctcatcatgt gtaccattct cagcaatttg accctcgttt
     5101 aaaacataga tattatcagc attttttata gtacttaatt tatgtgaaat aataattacg
     5161 gttttaccat gttgagttag taagtcaata tgctccataa ttttgttttc agttaaacta
     5221 tctaaggcac ttgtagcttc atcgaaaata tatatatcag gatcttttaa aaatgtacgt
     5281 gctaaagata agcgttggcc ttgtccgccc gatagattag ctccttcttt ttctaacata
     5341 gtgttaaact gatctgggaa tttctgtata aaatctaagg attctgctaa ttgacaagct
     5401 ttaacgatat cttcatcact tttgtattta ttgctaccat gtaaaagatt gtttttaatt
     5461 gtatcagcaa aaaggaatgt gttttgtgaa acatagccta tattcttacg taagtcagaa
     5521 agatcaatat catcaataat atagttatca atcataatat taccttctga agcagtgtaa
     5581 tagcgattga gtaacttacc tatagttgat ttaccactac cactttcacc aacaatagca
     5641 accttttgcc cttttttaat atttaaatta atatccttca ataccacact tcgaaagcca
     5701 tactgaaagt ttacattttc aatgcgaatg ttgtttttaa aagtataagg ttgtttagaa
     5761 gtatataatt cagtttcggt ctctaaatca gttatttcag caatacgacg tgctgcaaca
     5821 aatgaagatt gcagtgttgg ttgaatattt atgagacgtt caataggatc aaggtaataa
     5881 atagttaagg cattaaaagc taataaacta cctaacgtca tactatccgt catgactaag
     5941 taactaccaa gccacaatat aacaagactg atagttaatt ttaaaaagtt gttaaccgtt
     6001 aattgtatat tagaaaatct acccagtttt aataagtttt caataatacc attaaattta
     6061 gtagtaccaa tgtagaaacg atcgtcttca gattgataac ttttaatagt attactacca
     6121 tcaaaggatt ctattaaata tgaactcaat tcagcatctt tttcagccac cttttgatta
     6181 tatttttcaa aaggtttacg taaagtgtaa ctacaaataa taaaacaagg tataaaaata
     6241 attgttatca gtagtaacaa aggactttgc atataaagta atatagcacc gataataatc
     6301 atgaaagtat caactagcaa cgttaccgtt gaagatgata aagcttcacg aattttagat
     6361 gtatccatga aacgttgtag gatttcgcca gatttacgtg tatcaaaaaa gttcatcgga
     6421 agatgtaaaa catgataaaa ataatctttc attaaattaa catcgatttt caaacttaaa
     6481 tgtaagataa gttgaaacct taaataatta atgagtgcat tgattatgta taaaagtaaa
     6541 ataccgaagc taataatatg taaattttta agaacattgg atggaataat atgatcggtt
     6601 aataatttaa aatatagagc cccgacaata ccaacaatat taataaatag tgagataaaa
     6661 gcaataaata acaactttcc ataattattt ttaaatatat caataaaaat attaagatac
     6721 gagggtgatt cattgtcagt agtaaaatca tctgttttat caattaatac agcaatatta
     6781 gtccaatatt ttccaaattc agtacttgat aacttatatt tacctttagc aggatcgaca
     6841 atataaagcg tgttattttt tattttttca ataatgatat agtgatcata accttgttga
     6901 ttaataatat gtaccataac tggtaattgt gcttgtttta aatcatcaaa ggaatcagct
     6961 tttacgccag ttaactcaat accaatcttt ttacctgctt gtacgagacc atataaattt
     7021 gtacctaatt tatctgtttt agcatattcg cgcaaacgtg ggatagatac acgcttacca
     7081 taaaactgtg aaatcatggc aaggcaagta ggaccacaat ccttttcatc gtattgtctt
     7141 ataaatttta tagccatcat aatgagtcct ttcaataaaa tttaactcta ttttaataag
     7201 tataaatagt tagtattaaa cataagttaa ataatccttt tgataatgtt aaaagcgcta
     7261 aaaagtaaaa atatttgtct atatgtctac ttgtggtaca ccctaatcat acaaagagag
     7321 ttattgaatt tataataact taaacgtatg attagggtgt atattaattg tggagtgaaa
     7381 atgaatgatt ataggttatg caagagtatc ttcggtagat cagaatttag agagacagct
     7441 agataatttg aaaacatttg gcgtagagaa aatatttaca gagaaacaat cgggaaagtc
     7501 agtagaaaat agacccgtat ttcaagaagc acttaacttt gtgagaatgg gcgatagatt
     7561 tgtagtagaa tcgattgatc gcttaggtcg taattatgat gaagtgatta acacagttaa
     7621 ttatttaaag gataaagaag ttcaattgat gattactagt ttacctatga tgaatgaagt
     7681 gattggtaat ccactattag ataaatttat gaaagattta atcgttcaaa tcttagcaat
     7741 ggtttcagaa caagaacgaa atgaaagtaa acgtagacaa gcacaaggta ttcaagttgc
     7801 gaaagaaaaa ggtgtgtata aaggacgccc tttactatat tcacctaatg ctaaagatcc
     7861 tcaaaaacgt attatctacc atcgtgttgt tgaaatgtta gaagaaggca aagcaattag
     7921 taagattgcg aaagaggtta atatcacaag acagacagtt tatagaatta aaaatggtaa
     7981 gggattatct tgataaatgg attgttaatg caaatgagat cttctcacag cgtcctaaat
     8041 tatatgttat tcatctatta tgagattcta ataataagac aagaaaagag agtgcgaatt
     8101 cgcactctcc ttttgtgtag tactattgaa attttgtctt aaaaacgaac gtaatttaga
     8161 aataatattt attggtattt caagaaggtt ctgttgcaaa gtaaaaaata tagctaacca
     8221 ctaatttatc atgtcagtgt tcgcttaact tgctagcatg atgctaattt cgtggcatgg
     8281 cgaaaatccg tagatctgaa gagacctgcg gttcttttta tatagagcgt aaatacattc
     8341 aatacctttt aaagtattct ttgctgtatt gatactttga taccttgtct ttcttacttt
     8401 aatatgacgg tgatcttgct caatgaggtt attcagatat ttcgatgtac aatgacagtc
     8461 aggtttaagt ttaaaagctt taattacttt agccattgct accttcgttg aaggtgactg
     8521 atctgtaatt accttttgag gtttaccaaa ttgtttaatg agacgtttga taaacgcata
     8581 tgctgaatga ttatctcgtt gcttacgcaa ccaaatatct aatgtatgtc cctctgcatc
     8641 aatggcacga tataaatagc tccattttcc ttttattttg atgtacgtct catcaatacg
     8701 ccatttgtaa taagcttttt tatgcttttt cttccaaatt cgatataaaa ttggggcata
     8761 ttcttgaacc caacggtaga ccgttgaatg atgaacgttt acaccacgtt cccttaatat
     8821 ttcagatata tcacgataac tcaatgcata tcttagatag tagccaacgg ctacagtgat
     8881 aacatccttg ttaaattgtt tatatctgaa atagttcata cagaagactc ctttttgtta
     8941 aaattatact ataaattcaa ctttgcaaca gaaccatttt ttgaatacct aaaagaacgc
     9001 ggtttacaag gtacggaact cgttatttct gatgcgcaca aaggattagt ctctgccatt
     9061 agaaaatcct tcaccaacgt aagttggcaa agatgccaag ttcacttcct aagaaatatc
     9121 tttaccacca ttcctaaaaa aaattcaaaa tctttcagag aagctgttaa aggaattttt
     9181 aagttcacag atattaactt agcgcgtgag gctaaaaatc gattgattca tgattatatc
     9241 gatcaaccaa aatattcaaa agcttgcgca tcattggatg atggattcga agacgccttt
     9301 caatataccg tacaaggaaa ttcccacaat cgactaaaga gtaccaatct aattgaacga
     9361 ctgaatcaag aagtacgcag aagagaaaag attattcgca tcttccccaa tcaaacatca
     9421 gccaatcgct taattggagc cgttcttatg gacctacatg atgaatggat ttattcttca
     9481 agaaaataca tcaattttga taagtagaaa tggtaaaaac attgtatagc attttacaca
     9541 ggagtctgga cttgactgag tttatggaag aagttttaat tgatgataat atggtttttg
     9601 atattgataa tttaaaagga tttcttaatg ataccagttc atttgggttt atagctaaag
     9661 aaaataataa aattatagga tttgcatatt gctatacact tttaagacct gatggaaaaa
     9721 caatgtttta tttacactca ataggaatgt tacctaacta tcaagacaaa ggttatggtt
     9781 caaaattatt atcttttatt aaggaatatt ctaaagagat tggttgttct gaaatgtttt
     9841 taataactga taaaggtaat cctagagctt gccatgtata tgaaaaatta ggtggtaaaa
     9901 atgattataa agatgaaata gtatatgtat atgattatga aaaaggtgat aaataaatga
     9961 atatagttga aaatgaaata tgtataagaa ctttaataga tgatgatttt cctttgatgt
    10021 taaaatggtt aactgatgaa agagtattag aattttatgg tggtagagat aaaaaatata
    10081 cattagaatc attaaaaaaa cattatacag agccttggga agatgaagtt tttagagtaa
    10141 ttattgaata taacaatgtt cctattggat atggacaaat atataaaatg tatgatgagt
    10201 tatatactga ttatcattat ccaaaaactg atgagatagt ctatggtatg gatcaattta
    10261 taggagagcc aaattattgg agtaaaggaa ttggtacaag atatattaaa ttgatttttg
    10321 aatttttgaa aaaagaaaga aatgctaatg cagttatttt agaccctcat aaaaataatc
    10381 caagagcaat aagggcatac caaaaatctg gttttagaat tattgaagat ttgccagaac
    10441 atgaattaca cgagggcaaa aaagaagatt gttatttaat ggaatataga tatgatgata
    10501 atgccacaaa tgttaaggca atgaaatatt taattgagca ttactttgat aatttcaaag
    10561 tagatagtat tgaaataatc ggtagtggtt atgatagtgt ggcatattta gttaataatg
    10621 aatacatttt taaaacaaaa tttagtacta ataagaaaaa aggttatgca aaagaaaaag
    10681 caatatataa ttttttaaat acaaatttag aaactaatgt aaaaattcct aatattgaat
    10741 attcgtatat tagtgatgaa ttatctatac taggttataa agaaattaaa ggaacttttt
    10801 taacaccaga aatttattct actatgtcag aagaagaaca aaatttgtta aaacgagata
    10861 ttgccagttt tttaagacaa atgcacggtt tagattatac agatattagt gaatgtacta
    10921 ttgataataa acaaaatgta ttagaagagt atatattgtt gcgtgaaact atttataatg
    10981 atttaactga tatagaaaaa gattatatag aaagttttat ggaaagacta aatgcaacaa
    11041 cagtttttga gggtaaaaag tgtttatgcc ataatgattt tagttgtaat catctattgt
    11101 tagatggcaa taatagatta actggaataa ttgattttgg agattctgga attatagatg
    11161 aatattgtga ttttatatac ttacttgaag atagtgaaga agaaatagga acaaattttg
    11221 gagaagatat attaagaatg tatggaaata tagatattga gaaagcaaaa gaatatcaag
    11281 atatagttga agaatattat cctattgaaa ctattgttta tggaattaaa aatattaaac
    11341 aggaatttat cgaaaatggt agaaaagaaa tttataaaag gacttataaa gattgattat
    11401 ataatatatg aaaagctatt ataaaagaca ttagtattaa atagtttaaa aaaatgaaaa
    11461 ataataaagg aagtgagtca agtccagact cctgtgtaaa atgcggttct gttgcaaagt
    11521 aaaaaatata gctaaccact aatttatcat gtcagtgttc gcttaacttg ctagcatgat
    11581 gctaatttcg tggcatggcg aaaatccgta gatctgaaga gacctgcggt tctttttata
    11641 tagagcgtaa atacattcaa taccttttaa agtattcttt gctgtattga tactttgata
    11701 ccttgtcttt cttactttaa tatgacggtg atcttgctca atgaggttat tcagatattt
    11761 cgatgtacaa tgacagtcag gtttaagttt aaaagcttta attactttag ccattgctac
    11821 cttcgttgaa ggtgactgat ctgtaattac cttttgaggt ttaccaaatt gtttaatgag
    11881 acgtttgata aacgcatatg ctgaatgatt atctcgttgc ttacgcaacc aaatatctaa
    11941 tgtatgtccc tctgcatcaa tggcacgata taaatagctc cattttcctt ttattttgat
    12001 gtacgtctca tcaatacgcc atttgtaata agctttttta tgctttttct tccaaattcg
    12061 atataaaatt ggggcatatt cttgaaccca acggtagacc gttgaatgat gaacgtttac
    12121 accacgttcc cttaatattt cagatatatc acgataactc
//
