LOCUS       NZ_CP122692.1          13671 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP122692.1 Escherichia coli strain ETEC4065 plasmid unnamed2,
            complete sequence.
ACCESSION   NZ_CP122692
VERSION     NZ_CP122692.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-06-07 23:59:02
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 66881
            Orig. end    :: 80552
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13671
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[5000:8671]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..8671
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..13671
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13671
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             1624..2037
                     /locus_tag="ctg1_79"
                     /transl_table=11
                     /translation="MFFIENEGQAVARTDYWQSVQAQAGYVYLSWNAGAARLLVPDAAK
                     HLLREMRGAEYVIISKGTLHGRDVLELVFEDGSDAPFVIHMLSEQCDRLLPENNQGGGF
                     VVTVWTRGGNQLRYPGKYRVVENLPDVSPWSEH"
     CDS             2039..2821
                     /gene_functions="other (smcogs) SMCOG1077:phage integrase
                     family protein (Score: 96.2; E-value: 5.2e-29)"
                     /gene_kind="other"
                     /locus_tag="ctg1_80"
                     /transl_table=11
                     /translation="MQHLPAPIHHARDAAQLPVAIDYPAALALRQMSMVHDELPKYLLA
                     PEVSALLHYVPDLRRKMLLATLWNTGARINEALALTRGDFSLTPPYPFVQLATLKQRTE
                     KAARTAGRMPAGQQTHRLVPLSDSWYVSQLQTMVATLKIPMERRNKRTGRTEKARIWEV
                     TDRTVRTWIGEAVAAAAADGVTFSVPVTPHTFRHSYAMHMLYAGIPLKVLQSLMGHKSI
                     SSTEVYTKVFALDVAARHRVQFSMPESDAVTMLKNRHA"
     CDS             2994..3347
                     /locus_tag="ctg1_81"
                     /transl_table=11
                     /translation="MKVISMKFIFILTIIALAAVFFWSEDKGPACYQVSDEQARTFVKN
                     DYLQRMKRWDNDVQLLGTEIPKITWEKIERSLTDVEDEKTLLVPFKAEGPEGKRMYYGM
                     YHCEEGYVEYAND"
     CDS             complement(3397..4212)
                     /locus_tag="ctg1_82"
                     /transl_table=11
                     /translation="METLTVHAPSPSTNLPSYGNGAFSLSAPHVPGAGPLLVRVVYSFF
                     QSPNMCLQALTQFEDYIKKHGASNPLTLQIISTNIGYFCNADRNLVLHPGISVYDAYHF
                     AKPAPSQYDYRSMNMKKMSGNVTTPIVALAHYLWGNGAERSVNIANIGLKISPMKINQI
                     KDIIKSGVVGTFPVSTKFTHATGDYNVITGAYLGNITLKTEGTLTISANGSWTYNGVVR
                     SYDDKYDFNASTHRGIIGESLTRLGAMFSGKEYQILLPGEIHIKESGKR"
     CDS             4456..4983
                     /locus_tag="ctg1_83"
                     /transl_table=11
                     /translation="MTSNKDKNKKANEILYAFSIIGIIPLMAILILRINNQYSQVLYYL
                     YNKVAFLPSITSLHDPVMTTLMSNYNKTAPVMGILVFLCTYKTREIIKPVTRKLVVQSC
                     FWGPVFYAILIYITLFYNLELTTAGGFFKLLSHNVITLFILYCSIYFTVLTMTYAILLM
                     PLLVIKYFKGRQ"
     CDS             complement(5001..6113)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Cloacin"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_84"
                     /sec_met_domain="Cloacin (E-value: 6.3e-68, bitscore:
                     221.2, seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVTQQLEQVTDIPASQLPAAGNNVPVKYRLTDLMQNGTQYMAIIG
                     GIPMTVPVVDAVPVPDRSRPGTNIKDVYSAPVSPNLPDLVLSVGQMNTPVRSNPEIQED
                     GVISETGNYVEAGYTMSSNNHDVIVRFPEGSGVSPLYISAVEILDSNSLSQRQEVENNA
                     KDDFRVKKEQENDEKTVLTKTSEVIISVGDKVGEYLGDKYKALSREIAENINNFQGKTI
                     RSYDDAMSSINKLMANPSLKINATDKEAIVNAWKAFNAEDMGNKFAALGKTFKAADYAI
                     KANNIREKSIEGYQTGNWGPLMLEVESWVISGMASAVALSLFSLTLGSALIAFGLSATV
                     VGFVGVVIAGAIGAFIDDKFVDELNHKIIK"
     CDS             complement(6217..7014)
                     /gene_functions="other (smcogs) SMCOG1151:transposase
                     (Score: 291.8; E-value: 4.7e-89)"
                     /gene_kind="other"
                     /locus_tag="ctg1_85"
                     /transl_table=11
                     /translation="MHELEVLLSRLKMEHLSYHVESLLEQAAKKELNYREFLCMALQQE
                     WNGRHQRGMESRLKQARLPWVKTLEQFDFTFQPGIDRKVVRELAGLAFVERSENVILLG
                     PPGVGKTHLAIALGVKAVDAGHRVLFMPLDRLIATLMKAKQENRLERQLQQLSYARVLI
                     LDEIGYLPMNREEASLFFRLLNRRYEKASIILTSNKGFADWGEMFGDHVLATAILDRLL
                     HHSTTLNIKGESYRLKEKRKAGVLTKNTTPISDDEMVESGQHQ"
     CDS             complement(7014..8186)
                     /gene_functions="other (smcogs) SMCOG1213:transposase
                     (Score: 326.5; E-value: 3.1e-99)"
                     /gene_kind="other"
                     /locus_tag="ctg1_86"
                     /transl_table=11
                     /translation="MLSREDFYMIKQMRQQGAYIVDIAAQIGCSERTVRRYLKYPEPPA
                     RKTRHKMVKLKPFMDYIDMRLAENVWNSEVIFAEIKAMGYTGGRSMLRYYIQPKRKMRP
                     SKRTVRFETQPGYQLQHDWGEVEVEVAGQRCKVNFAVNTLGFSRRFHVFAAPKQDAEHT
                     YESLVRAFRYFGGCVKTVLVDNQKAAVVKNNNGKVVFNSGFLLLADHYNFLPRACRPRR
                     ARTKGKVERMVKYLKENFFVRYRRFDSFTHVNQQLEQWIADVADKRELRQFKETPEQRF
                     ALEQEHLQPLPDTDFDTSYFDIRHVSWDSYIEVGGNRYSVPEALCGQPVSIRISLDDEL
                     RIYSNEKLVASHRLCSASSGWQTVPEHHAPLWQQVSQVEHRPLSAYEELL"
     CDS             complement(8282..8671)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Cloacin"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_87"
                     /sec_met_domain="Cloacin (E-value: 2e-14, bitscore: 46.4,
                     seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDNEGSVPTEGIDYGDTMVVWPSTGRIPGGDVKPGGSSGLAPSM
                     PPGWGDYSPQGIALVQSILFPGIIRRIILDKELEEGDWSGWSVSVHSPWGNEKVSAART
                     VLENGLRGGLPEPSRPAAVSFARLC"
     CDS             9112..9624
                     /locus_tag="ctg1_88"
                     /transl_table=11
                     /translation="MNISVEDLFPESFQRIKEEEEANRPDPNWFAHLPPEKINAYMSKY
                     PFKSFDDIPLDNSGLQYPSLQELEFYFPPAALAANCHQLPERMRQKPVVTMINGLTLLR
                     SLGVQAFNIDPRRWHKIKTYLSQGTIEYPQMSEDGKVIIDGRHRILLIMQIYKVTDVPV
                     FFLKGIS"
     CDS             complement(9775..10125)
                     /locus_tag="ctg1_89"
                     /transl_table=11
                     /translation="MDKRRTIAFKLNPDVNQTDKIVCDTLDSIPQGERSRLNRAALTAG
                     LALYRQDPRAPFLLCELLTKETTFSDIVNILRSLFPKEMADFNSSTITQPSSQQEQRSD
                     EETKKNAMKLIN"
     CDS             complement(10128..11090)
                     /locus_tag="ctg1_90"
                     /transl_table=11
                     /translation="MLVFIDDGSTNIKLQWQESDGTIKQHISPNSFKREWAVSFGDKKV
                     FNYTLNGEQYSFDPISPDAVVTTNIAWQYSDVNVVAVHHALLTSGLPVSEVDIVCTLPL
                     TEYYDRNNQPNTENIERKKANFRKKITLNGGDTFTIKDVKVMPESIPAGYEVLQELDEL
                     DSLLIIDLGGTTLDISQVMGKLSGISKIYGDSSLGVSLVTSAVKDALSLARTKGSSYLA
                     DDIIIHRKDNNYLKQRINDENKISIVTEAMNEALRKLEQRVLNTLNEFSGYTHVMVIGG
                     GAELICDAVKKHSQIRDERFFKTNNSQYDLVNGMYLIGN"
     CDS             11608..12291
                     /locus_tag="ctg1_91"
                     /transl_table=11
                     /translation="MSRFIQGDCVRVMATFPGNAVDFILTDPPYLVGFRDRQGRTIAGD
                     KTDEWLQPACNEMYRVLKKDALMVSFYGWNRVDRFMAAWKNAGFSVVGHLVFTKTYTSK
                     AAYVGYRHECAYILAKGRPALPQKPLPDVLGWKYSGNRHHPTEKPVTSLQPLIESFTHP
                     NAIVLDPFAGSGSTCVAALQSGRRYIGIELLEQYHRAGQQRLAAVQRAMQQGAANDNWF
                     EPEAA"
     CDS             12292..12513
                     /locus_tag="ctg1_92"
                     /transl_table=11
                     /translation="MNYAGHEKLRADVAEVANTMCDLRARLNDMEHRCRFDSDVLVERL
                     TRQTLYRANRLFMEAYTEILELDSCFKD"
     CDS             12527..12961
                     /locus_tag="ctg1_93"
                     /transl_table=11
                     /translation="MYGTCETLCRELAAKYPGDAPLMLVIWSPEEIQALADGMDISLSD
                     HEIRTVLARLEDIPEDQRIESGISSGVAMEIINNVRENRQVTVPAELLASLIQTAEQAL
                     WKREWAARDNGLALPECVTRRQAVVNQARALLKNNTREND"
ORIGIN
        1 taggtttgtc gcgctgaggt tcgcgtccag taaaaaaggc aataagtcca taaataatcc
       61 agatggcata agctaataat acatacacaa cggaaagcgg tgctaaaggc accaacaacc
      121 agcaacgatg aaaccaggcg ctaaaagcac caataacaca aactacgccg acccagataa
      181 gcggaaacat tgccaacacc acaccatgcg gcccggtggt gatgaattca ttaaaccagg
      241 tagtgagata aatcccaacg ccataaagca caaccaacag cataggaaat atactgaaga
      301 taccgaaacg gctaaataaa agccttttat gcaggcgcat acagaccgca tagcccacaa
      361 tccatcgtcg ccaacgacgc cattcatcaa ggagactatt acattcctgt gggtaaacga
      421 tgcagcgatt cgcctgacgg atgcggtaac cattggcgac caatgtccag gtaaggtcga
      481 gatcttcaac ttttgttcga tctgaaaaac cgaatttacg cagcacatcg gtacggaaca
      541 tcccgcagga cccgctgata ataaacggtg accgcccgca tgaatcactg aacaatatga
      601 cgccagagga atatcaacaa caccattatc tggcagggat ctcaaaaatg cctgaaacta
      661 aaacgggtct attacattac caatgtactc tttcataaag taaaaatcct gatgggaaag
      721 gaaaaagatt gcaccctcat tgtgtatggt gattgttttt ccaggaagtt atacgaactt
      781 gagtattgca ctgataaaca taatgagctt ggcataaaaa tggtaaataa accagaaaag
      841 gggtatcagc cacatgttct tccatatatt attggaaact gtacaatata tttcgttccg
      901 aactgtctgg ataattactc attactgatc cggaattcat cttttggtct tttacgtctg
      961 ttccgttacc ctgatgatac gatgttctgc acgttctgca gggaagatgt agatgctcca
     1021 cttaaaagta ttataaccca catctgggag ctggatgtag agatgacaga tcctgtcata
     1081 gctatgttta atcacgtctg agtgccgtga gtgatttctg tcttttatgc aacagtgcca
     1141 agatattgta atcaaaaaaa gcattaatgc attttggaca gtaatctatt ttaactgatg
     1201 acatagaagc attaatcttt ctttttcttc aggaagatcc gaaaactcct ggttcaggat
     1261 cttcctctcc cccacacaac gccacctcct gtaagtacaa catgtagtgc tgcattcagc
     1321 tgcttatgac actatatgtt gtgttatctc cctgacctgt gatgcgccgc gcaggggcgg
     1381 aaaacagcaa tatgatgatt tcctctgcgt ggtacacttc cggaaagttg tgatattcag
     1441 gaaagtcgga tctgacggaa acggctctcc ggtaatttaa cggcgtggtt atatgtatgc
     1501 ttgttatcat ggtgatgatg ataacggcat gatgttatca gacggcgtga cggtaagggc
     1561 agtgatgatg gatgacgtta tcgcatgacc gtccctgccc ggaaaagaaa aaaggagtca
     1621 cccatgtttt ttattgagaa tgaaggtcag gctgtcgcca gaacggatta ctggcagtct
     1681 gtacaggcgc aggccggata tgtctacctc agctggaatg ccggcgcagc caggctgctt
     1741 gtcccggatg cggcaaaaca tttactcagg gagatgcggg gggctgagta cgtcatcatc
     1801 agtaagggaa cgctgcatgg ccgcgatgtg ctggaactgg tatttgaaga cggcagcgat
     1861 gcgccgtttg tgatccacat gctgagtgag cagtgcgatc gcctgctccc cgaaaacaac
     1921 cagggagggg gttttgttgt caccgtctgg acgcgtggcg gtaaccagct ccgttatccg
     1981 ggaaagtacc gggttgtgga aaacctgccc gacgtttccc cgtggagtga acactgatat
     2041 gcagcacctg ccggcaccga tccaccatgc ccgggatgct gctcagcttc ctgttgccat
     2101 cgattatccg gcagcgctgg cactccgcca gatgtcgatg gttcatgatg aactgccaaa
     2161 atacctgctg gcccctgaag tgagcgccct gctccattac gtcccggatc tgcgccgcaa
     2221 gatgctgctg gccacactgt ggaacaccgg tgcgcgcatt aatgaagcac tggcgctgac
     2281 gcggggggat ttttcgctca cgcccccgta tccgtttgtg cagctggcca ctctgaagca
     2341 gcggacagaa aaagccgcca ggacggcagg aagaatgcca gccggtcagc agactcaccg
     2401 gctggttccg ctctccgact cctggtacgt cagccagctg cagacgatgg tggccacact
     2461 gaaaatcccc atggaacggc gtaataaacg aacaggcagg acagagaaag cgcggatctg
     2521 ggaagtgacg gacagaacgg tcaggacctg gattggggag gcggttgccg ccgctgccgc
     2581 tgatggtgtg acgttctctg tcccggtcac gccacatacg ttccgccatt cctatgcgat
     2641 gcacatgctg tatgccggta taccgctgaa ggtcctgcag agcctgatgg ggcataagtc
     2701 catcagctca acggaggtct acacgaaggt gtttgcactg gatgtggctg cacggcaccg
     2761 ggtgcagttt tcgatgcctg agtccgatgc ggtcacaatg ctgaaaaaca gacatgcata
     2821 ataagtcaca attatgaatt gtgatttctt ctataaaaaa gagaccactg caatatgtga
     2881 tctcttgtat tatttcataa ttgttaaagc cacttcacag tatgctcaca ttgtacggat
     2941 atattcgtaa tgttttttta tatcgaatga acgacagaag ttgtggagat tttatgaaag
     3001 taattagcat gaaatttatt tttattttaa cgattattgc tcttgctgct gtttttttct
     3061 ggtctgaaga taaaggtccg gcatgctatc aggtcagcga tgaacaggcc agaacgtttg
     3121 taaaaaatga ttacctgcaa agaatgaaac gctgggacaa cgatgtacaa cttcttggta
     3181 cagaaatccc gaaaattaca tgggaaaaga ttgagagaag tttaacagat gttgaagatg
     3241 aaaaaacact tcttgtccca tttaaagctg aaggcccgga gggtaagaga atgtattatg
     3301 gcatgtacca ttgtgaggag ggatatgttg aatatgcgaa tgactaatac actgttataa
     3361 aggctgcata aaaaggccgg aaccccggtc cttatattat cgcttaccac tttctttaat
     3421 gtgaatttca ccaggaagca gtatctggta ctctttacca gaaaacatcg ccccgagcct
     3481 tgtgagcgac tctccgataa tgccacggtg agtgctggcg ttaaaatcgt atttatcatc
     3541 atatgaacga acaacgccat tgtaagtcca ggagccattg gcagagatag ttaaagtacc
     3601 ttctgttttc agtgtgatat taccaagata tgcaccggta ataacattat aatcaccagt
     3661 ggcatgtgtg aactttgtag aaacagggaa tgtacctact acaccagatt ttataatgtc
     3721 ttttatctga ttaattttca taggggaaat tttaagacca atgttggcga tattaacgct
     3781 cctttcagcg ccattacccc ataaatagtg agcaagcgcc acaattggtg tagtgacatt
     3841 accgctcatt tttttcatat tcattgagcg atagtcatat tgacttggcg ctggttttgc
     3901 gaagtggtaa gcgtcataaa cgcttattcc agggtgaaga accagatttc ggtcggcgtt
     3961 acagaagtaa ccaatatttg tcgatatgat ctgcaatgtg agagggttgc tggccccatg
     4021 ttttttgatg taatcctcaa attgagttaa agcctgaaga cacatgtttg gactctggaa
     4081 aaaactataa acaacccgga ctaaaagagg gccagcacca ggcacatgag gtgctgaaag
     4141 agaaaatgca ccattgccat aacttggtaa gttagttgat ggtgatggtg catgaacagt
     4201 taaggtttcc atacataatt ccttataagt taacaagata acagagttcg ccgctggcta
     4261 acgcctccgc cggcgaacaa accccatgag agaggctccc cataacattg tttgcctgat
     4321 atgccgttaa aaatggtagg gcagctcctg aactaccata tataagatat atatctgtac
     4381 actccattaa atactggaaa tatattgaga actctgatat ataatctata tataaaaata
     4441 caaaaaggta tatatatgac cagcaataaa gataagaaca agaaagcaaa cgaaatatta
     4501 tatgcatttt ccataatcgg gattattcca ttaatggcta tattaatact tcgaataaat
     4561 aatcaatatt ctcaagtgct gtactactta tataataagg tggcatttct cccttctatt
     4621 acatcattgc atgatcccgt catgacaaca cttatgtcaa actacaacaa gacagcacca
     4681 gttatgggta ttctcgtttt tctttgcaca tataagacaa gagaaatcat aaagccagta
     4741 acaagaaaac ttgttgtgca atcctgtttc tgggggcccg ttttttatgc cattctgatt
     4801 tatatcacac tgttctataa tctggaacta acaacagcag gtggtttttt taaattatta
     4861 tctcataatg tcatcactct gtttatttta tattgctcca tttactttac tgttttaacc
     4921 atgacatatg cgattttact gatgccattg cttgtcatta aatattttaa agggaggcag
     4981 taacactgcc ttccttttaa ttattttatg atcttgtgat tcaactcatc aacaaattta
     5041 tcatcgataa atgcaccaat agcacctgca ataactacgc caacaaaacc aacaactgtg
     5101 gccgaaagac caaaggctat aagggccgag cctaatgtca aagaaaacaa actaagagct
     5161 acagcagatg ccatcccact gataacccag gactcgactt ccagcattaa tggcccccag
     5221 ttaccagtct ggtaaccctc aatactcttc tccctgatgt tgtttgcctt tattgcataa
     5281 tctgctgctt tgaacgtttt acccaacgca gcaaatttat tccccatatc ctcagcatta
     5341 aatgctttcc acgcattcac aatggcttct ttgtccgttg catttatttt aaggctgggg
     5401 ttagccatta acttattaat ggaagacatt gcatcatcat aactacgaat cgtttttccc
     5461 tgaaaattat ttatattctc tgcaatttca cgggaaagcg ccttgtattt atctccaaga
     5521 tattccccga ctttgtcacc gacactaatg atgacctcgc tggtttttgt caggaccgtc
     5581 ttctcgtcat tttcttgttc tttcttgact ctgaagtcat cctttgcgtt attttcgact
     5641 tcctggcgct ggcttaaact attactgtcc agaatctcca cggctgaaat atatagcgga
     5701 gaaactccac tgccttcagg aaaacggaca atgacatcat gattattact ggacatcgta
     5761 taaccagcct caacataatt ccctgtctca gaaataacgc catcttcctg gatttcggga
     5821 ttagaccgaa ctggagtatt catctgaccc acacttaata ccaggtccgg tagatttggt
     5881 gatacagggg cactgtaaac atctttaata ttggttcccg gacgactccg gtccggaact
     5941 ggaacggcat ccactactgg cactgtcatc ggaatacctc cgataatagc catatattgt
     6001 gtaccattct gcataaggtc cgtcagacga tattttaccg gtacattatt acccgctgct
     6061 ggtaactggc tggcagggat atccgttacc tgctccagtt gctgtgtaac cataagacga
     6121 ataatttttt gctcatttcc ggaagcaggc tccagatgtc aacgccacga tttttaaccg
     6181 ttatttgcca ttttcatgcc cgctaagata ctttcgttac tgatgctgtc cgctttccac
     6241 catttcatca tcactgattg gcgttgtgtt tttggtcagc actcctgctt tacgtttctc
     6301 ttttaaccgg taactctctc ctttgatatt cagcgtagtt gagtgatgta gcagccggtc
     6361 caggatcgct gttgccagca cgtgatctcc gaacatttct ccccagtctg cgaacccttt
     6421 gtttgacgtc agtatgatgc tcgctttttc atatcgacgg ttcagtagcc ggaagaacag
     6481 gctggcttcc tctctgttca tcggcagata acctatttca tccaggatca acacccgggc
     6541 ataactcagt tgctgtagct gacgctccag ccggttttcc tgtttcgctt tcatcagtgt
     6601 cgcgatcagt ctgtccagtg gcataaacag tacccgatgt cccgcatcca ccgcttttac
     6661 gccaagagct atggccagat gcgtttttcc gacaccagga ggtcccagca ggatcacgtt
     6721 ttcgctgcgc tccacgaacg ccagaccagc cagttcccgg acaaccttac ggtcgatgcc
     6781 cggctggaag gtaaagtcga actgctccag cgttttgacc cacggcagac gagcctgctt
     6841 cagccgggac tccataccgc gctgatgcct gccgttccat tcctgctgta gcgccatgca
     6901 caggaactcc cggtaattca gctctttttt agctgcctgt tccagcaggc tttcaacgtg
     6961 ataactcaga tgctccattt tcaggcggct cagcaggact tccagctcat gcatcacaac
     7021 agctcctcat aggcactcag tggtcgatgt tccacctgac tgacctgctg ccagagcggg
     7081 gcatgatgct ccggcactgt ctgccagcca gacgatgccg aacagaggcg atgtgaggcc
     7141 accagtttct cattactgta gatccgcaac tcgtcatcca gcgatattcg tatcgatacc
     7201 ggctgaccac acagcgcttc gggaacgctg taacgattac cgccaacctc gatatagctg
     7261 tcccaggaca catggcggat gtcgaagtaa ctggtatcga agtccgtatc cggtaacggc
     7321 tgcagatgtt cctgctccag cgcgaagcgc tgttccggcg tttctttgaa ctggcgaagt
     7381 tcccgtttgt cagccacatc ggctatccat tgctccagtt gttgattgac atgagtgaag
     7441 ctgtcgaacc tgcggtaccg gacgaagaag ttctccttga ggtatttcac catccgctca
     7501 accttacctt ttgttctggc cctgcgtgga cggcatgccc gtggcaggaa gttatagtgg
     7561 tcggccagca acaggaatcc ggagttgaac acgactttcc cgttgttatt cttcaccacc
     7621 gcagccttct ggttatcaac cagcaccgtt ttcacacaac caccgaagta gcggaaggcg
     7681 cgaaccagtg attcgtaggt atgctcagca tcctgttttg gtgcggcgaa gacatggaag
     7741 cggcgggaga accccagcgt attaaccgca aagttaactt tgcaccgttg ccctgcaacc
     7801 tccacctcaa cttcgcccca gtcgtgctgg agctggtatc caggctgagt ttcgaagcga
     7861 actgttcttt ttgacggacg cattttacgt ttgggctgga tgtagtaacg cagcatggaa
     7921 cgtccgcccg tatagcccat tgccttaatc tccgcgaaga taacctcgct attccagaca
     7981 ttctctgcca ggcgcatgtc gatgtaatcc ataaacggtt tcagcttaac cattttgtgg
     8041 cgggtttttc tggctggcgg ttcagggtat ttgagatagc gtctgaccgt tcgttcagag
     8101 caaccaatct gagccgcaat atcgacaatg tacgcgccct gctggcgcat ttgctttatc
     8161 atgtaaaagt cctctctgct cagcatgttg atgtcctttt tggtgtgaga accttaagga
     8221 aacaacatgt tgggtggagc ggacaatcca aatggtgaat taccgtctta tatcactggc
     8281 gctaacacag acgggcaaaa gaaacagcag ccgggcgaga cggttctggc aaaccaccac
     8341 gtaaaccatt ttcaagaact gttcgtgcag cggaaacttt ctcgtttccc caggggctat
     8401 gcacactgac agaccatccc gaccagtctc cctcttcaag ttccttatca agaataatcc
     8461 ggcgaataat tccaggaaaa agaatacttt gtacaagtgc gataccttgt gggctgtaat
     8521 ccccccatcc cggaggcatg gatggagcga gacctgatga gcctccgggt ttcacatcac
     8581 cgcccggaat tcgtcctgtt gacggccaca caaccattgt gtccccgtaa tcaatacctt
     8641 ctgtcggtac actaccttca ttatcactca tagaaaacct ctttgacttt aaaaacaatc
     8701 aattaaaatt aaatactgta catataacca ctggttttat gtacagatca aaaattacgc
     8761 cgctgtgttt tctctgtcaa gactgtggat ttcaattttt gtgaaaacga tcaaaaaaca
     8821 ggcattcaca ccacgtgcta ttctcgcctg ataccacaaa aaacggcaca ggcataactg
     8881 ttctctggcc tcagcatgtt ttaatgaaac tatgatatga gacacctggg gggatactgt
     8941 cactttatgg catggtacac atcgtgatat gtgtacaggc cttgttagtt accgtaccgg
     9001 tcaggacgga cgacgggagt ttgaaaccag tgagttgttc tgtactggcg tgttttataa
     9061 tgaaatcctt atcggtggcg atgagcaatg ctctcaaggg aggatattgt gatgaacata
     9121 agtgtggaag atttgtttcc ggagtcattt caacgaatta aagaagaaga agaagcgaac
     9181 aggcctgatc ctaactggtt tgcacattta ccgcctgaaa aaatcaatgc gtatatgtcc
     9241 aagtatcctt tcaaatcctt tgatgatatt cctctggaca acagtgggtt gcaataccct
     9301 tcactacagg aactggagtt ttattttccc ccggcggccc tggctgctaa ttgccatcaa
     9361 cttcctgaga gaatgagaca aaagcctgtg gtcacgatga ttaatgggtt aaccctgtta
     9421 aggtcgcttg gcgttcaggc tttcaatatc gatccacgcc gatggcacaa aattaaaacc
     9481 tatttaagtc aaggaacgat tgaatatcca caaatgtccg aagacgggaa agtaattata
     9541 gatggcaggc atagaatact acttattatg cagatttata aagtaactga tgttcccgtt
     9601 ttttttctga aaggaataag ctgaacagtg caaagggtaa agctatactg atttttagac
     9661 tgtgatttgt tacgtagaaa taacttgtca gatgtaatct gtacatagct aaaaaatagg
     9721 tttgttgata cctttacccc gtttatgggg gtaaagatat caataaaaat ttaatcagtt
     9781 tattaacttc atcgcgtttt tttttgtctc ttcatcactt ctttgctcct gttgtgaaga
     9841 gggttgagtg attgttgaag aattaaaatc agccatctct tttggaaata gcgatctcaa
     9901 tatattcacg atatctgaaa atgtggtttc tttcgtcagc agttcacata aaaggaaagg
     9961 ggccctgggg tcttgtctgt ataaggccag acctgccgtc agtgcggccc ggttaaggcg
    10021 gctgcgttcc ccttgcggga tactgtccag tgtatcacaa acaattttat ctgtttgatt
    10081 tacatctgga tttagtttga aggcaatggt tctgcgcttg tccattatta attacctatg
    10141 agatacatac cgttaactaa atcatattga gagttattgg ttttgaaaaa acgttcatca
    10201 cgaatctgtg agtgtttttt tactgcatcg catattaatt ctgcgccacc gcctataacc
    10261 ataacatgcg tataaccaga aaattcattg agcgtattta atacacgttg ctcaagttta
    10321 cgaagtgctt cattcattgc ttcggtgact attgatattt tgttctcatc attaattcgt
    10381 tgcttcagat agttgttgtc ttttctgtga ataattatat cgtcagcaag atagctactt
    10441 ccttttgttc tcgcaagaga aagtgcatct tttactgcag atgtgaccag agatacacca
    10501 agagatgagt ctccgtatat tttactgatc cctgataatt tccccattac ctgagaaata
    10561 tctaatgtgg tgcccccgag gtctataatt aataaagaat ctaactcatc cagttcttgt
    10621 agaacttcat aacctgctgg tatagattca ggcatgactt ttacatcttt tattgtgaat
    10681 gtatccccac catttaatgt aatttttttc cggaagtttg ctttcttacg ctcaatattt
    10741 tccgtattgg gttggttatt cctgtcgtaa tactctgtca gaggaagtgt gcaaacaata
    10801 tccacttcgc ttaccggcag accactggtc agtaaggcgt gatgcaccgc aacgacatta
    10861 acgtcgctgt attgccatgc gatattggtt gtgactacag catccgggct gattggatca
    10921 aatgaatact gttcgccgtt cagtgtgtag ttaaagacct ttttatcacc aaaagagact
    10981 gcccactcgc gtttgaagct gttcgggcta atgtgctgtt taattgttcc gtcgctttcc
    11041 tgccactgta gtttgatgtt tgttgaaccg tcatcaatga ataccaacat ttataaaact
    11101 ccttatggtg ttttttttgg tgtgtatttg ggtgtgtttt gggttttaag tgggtttatt
    11161 tgtcaagttt accccatttt aaccatcaat caatgattat ttgtcttgtt tcggtgtttt
    11221 attgggtttg gtttgggttg tttttgggtt ttgttttgtg ggtaacaaaa gatgtcgccg
    11281 ggctcctctt tttactgcgc cggctgacgc ggcgcggcag gaacgctgcc tgtggtcagt
    11341 gtcccgcgtc cggccgggca cgggacgggc gcttttaccg ctcccggctg gcgttggtga
    11401 cagtgtacgc cagccgggag cccttttctg atgaacgccc ttcaagccgc tttcgcggca
    11461 tatcctcgcc gtcaaaaaga cgacggctgc ggtattccac ggtcggcctg acccgttacc
    11521 ggacgcggtg aacagcccac aggcagcggg gaacgggcgc cacaggggcg ccctcccggt
    11581 gccctctgta agagaaggag tgctgttatg tcccgtttta tccagggtga ctgcgtgcgt
    11641 gttatggcca cgtttccggg caatgctgtc gatttcatcc tcaccgaccc gccatatctc
    11701 gtcggtttcc gtgaccgtca ggggcgtacc atcgccggcg ataaaaccga tgaatggctg
    11761 caaccggcct gtaatgaaat gtaccgcgta ctcaaaaaag atgcgctgat ggtgagcttc
    11821 tatggctgga accgcgtcga tcgctttatg gccgcctgga aaaatgcggg attcagcgtg
    11881 gttggccacc tggtatttac caaaacctac acatcgaagg ccgcatatgt gggctatcgc
    11941 cacgaatgcg cttacatcct ggcaaaaggg cgtccggcgc tgcctcagaa gccattgccc
    12001 gacgtgctgg gctggaaata ttcaggcaac cgccatcacc cgacggaaaa gcccgttacc
    12061 agcctgcaac cactgattga gagcttcaca catccgaacg cgattgtgct ggacccgttt
    12121 gcaggcagcg gctcaacctg cgtggccgcc ctccagtccg gacgccggta tatcggtatc
    12181 gagctgcttg aacagtatca ccgtgccgga cagcaacgac tggccgccgt gcaacgggcc
    12241 atgcagcagg gggccgcgaa tgataactgg tttgaaccgg aggctgcgta aatgaactat
    12301 gccggacacg aaaaacttcg cgccgacgtg gcggaggtgg ccaacaccat gtgtgacctt
    12361 cgggccaggc tgaacgatat ggagcatcgc tgtcgctttg attccgatgt gcttgttgaa
    12421 cgtctgacac gccagacgct gtatcgcgcc aatcgcctgt ttatggaggc gtataccgaa
    12481 attctggaac tggattcctg cttcaaagat tgagaaggag acgagaatgt acggaacatg
    12541 cgaaacgcta tgccgggagc tggcagcaaa gtatccggga gacgcgccgc tgatgctggt
    12601 tatctggtcc ccggaagaaa ttcaggccct cgctgacgga atggatattt ccctgtccga
    12661 tcatgaaatc aggaccgtcc tggcgcggct ggaggacatc ccggaagacc agcggattga
    12721 gtccggtatt tcttccggcg tggcgatgga gatcatcaat aacgtgagag aaaaccgcca
    12781 ggtgaccgtc cctgctgaac tgctggcgtc cctgattcag accgccgaac aggcactgtg
    12841 gaaacgtgag tgggccgccc gtgataacgg cctcgccctc ccggaatgcg tcacccgccg
    12901 acaggcggtg gttaatcagg cccgcgccct gctgaaaaac aacacacgcg aaaacgactg
    12961 atgttatcgc cgcctgcggg cggcgattca gggagaccat gaatcatgaa cgaaacgctg
    13021 aatgcactga tttgtcgcca cgcccgtaac ctgctgctgg cgcagggctg gccggaagag
    13081 acggatgttg accagcgtaa cccgaagtat ccgggctgga tcagcattta tgttctgctg
    13141 gatgcgcccc ggctggcgac cttacttatc aaccgtcacg gcggcgtact gccgccgctc
    13201 ctggcctccg ccattcagaa actgaccgga accggggcgg aacttgttct gtccggcagt
    13261 cagtggcagt cgctgccggt acttccggca gacggaacgc aggtgtcttt cccgtatgcc
    13321 ggtgagtggc tggcagaaga cgaaatcagg gctgtacttg cggcggtgcg cgatgcaata
    13381 cgaagcatct gttaccaggt ggcagacgat gcgctgcgta tccgggcggc gctgaccacc
    13441 accggtcaga cgttgctgac ccgccagacg cgccgctttc gtctggttgt gaaggaaagc
    13501 gatcacccct gctggctcga tgaagatgac gaaaacctgc ccgtggtgct cgatgccatc
    13561 gtgaaccggg gagcacgttt ttcgtcggtg gaaatgtacc tggtcagcga ttgtattgag
    13621 catatcctgt ccagtgggct ggcctgcgat gtgctgcgta taccggatga a
//
