LOCUS       NZ_CP122585.1          15014 bp    DNA              UNK 01-JAN-1980
DEFINITION  NZ_CP122585.1 Klebsiella pneumoniae strain NCRE-61 plasmid
            pNCRE-61-15.0, complete sequence.
ACCESSION   NZ_CP122585
VERSION     NZ_CP122585.1
KEYWORDS    .
SOURCE      .
  ORGANISM  .
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-06-07 22:20:06
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             2..2545
                     /locus_tag="ctg1_1"
                     /transl_table=11
                     /translation="MRIILPGATTLTRLISEVREKATLRLWNKLALIPSAEQRSQLEML
                     LGPTDCSRLSLLESLKKGPVTISGPAFNEAIERWKTLNDFGLHAENLSTLPAVRLKNLA
                     RYAGMTSVFNIARMSPQKRMAVLVAFVLAWETLALDDALDVLDAMLAVIIRDARKIGQK
                     KRLRSLKDLDKSALALASACSYLLKEETPDESIRAEVFSYIPRQKLAEIITLVREIARP
                     SDDNFHEEMVEQYGRVRRFLPHLLNTVKFSSAPAGVTTLNACDYLSREFSSRRQFFDDA
                     PTEIISRSWKRLVINKEKHITRRGYTLCFLSKLQDSLRRRDVYVTGSNRWGDPRARLLQ
                     GADWQANRIKVYRSLGHPTDPQEAIKSLGHQLDSRYRQVAARLCENEAVELDVSGPKPR
                     LTISPLASLDEPDSLKRLSKMISDLLPPVDLTELLLEINAHTGFADEFFHASEASARVD
                     DLPVSISAVLMAEACNIGLEPLIRSNVPALTRHRLNWTKANYLRAETITSANARLVDFQ
                     ATLPLAQIWGGGEVASADGMRFVTPVRTINAGPNRKYFGNNRGITWYNFVSDQYSGFHG
                     IVIPGTLRDSIFVLEGLLEQETGLNPTEIMTDTAGASELVFGLFWLLGYQFSPRLADAG
                     ASVFWRMDHDADYGVLNDIARGQSDPRKIVLQWDEMIRTAGSLKLGKVQVSVLVRSLLK
                     SERPSGLTQAIIEVGRINKTLYLLNYIDDEDYRRRILTQLNRGESRHAVARAICHGQKG
                     EIRKRYTDGQEDQLGTLGLVTNAVVLWNTIYMQAALDHLRAQGETLNDEDIARLSPLCH
                     GHINMLGHYSFTLAELVTKGHLRPLKEASEAENVA"
     protocluster    1493..13178
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[6492:8178]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      6493..8178
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1493..13178
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1493..13178
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             2538..2777
                     /locus_tag="ctg1_2"
                     /transl_table=11
                     /translation="MLNVSFRSTERQTPYLFNRKANGIDEIWYICPDRPTLVRVQRAIL
                     AVDEIVNPQTGEARKTAELDRERLFACFKFMTTE"
     CDS             2784..3314
                     /locus_tag="ctg1_3"
                     /transl_table=11
                     /translation="MALYMVFIEDVEDKDGERCIMPTSEHLEDMAVMAWQTGAYVFRFE
                     DQAQHLAMMKFIGMYHERLNSDDKATYYFTGKNPAWEREKPAGMKLCDYLYRKVEQFAI
                     ENGVQVLDAGKYTPEQIGAMIDVVSERYGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRRWPFGKK"
     CDS             complement(3342..3521)
                     /locus_tag="ctg1_4"
                     /transl_table=11
                     /translation="MTKQEKTALNMAKFIKDQSLLLLEKLNELDMDTPADMCERLHEDA
                     ETLWQVMQDKLGEE"
     CDS             complement(3547..3975)
                     /locus_tag="ctg1_5"
                     /transl_table=11
                     /translation="MAKTLLNLSQAAQAAGITRRTLYNHVKQGKVTVSRDGKNNPVVDV
                     SELIRVYGNVNIPEKQIPGISHRENTQKNFPQEQLLAMQKELADLRQAVTLMLEDKTSR
                     EEERRQHDDERRKLQAEVDRLTTELTQKKKRFWSGWFS"
     CDS             complement(4139..4453)
                     /locus_tag="ctg1_6"
                     /transl_table=11
                     /translation="MPQVTISALAQRDLQRLQDFLKTKNRLAARKAGEVIVRAIQQLKT
                     LPDIGRPVPFLPLEYQELVIGFGDSGYVMLYRHDREMDRIVIVTVRHQKESGYPGADSL
                     "
     CDS             complement(4441..4719)
                     /locus_tag="ctg1_7"
                     /transl_table=11
                     /translation="MSSATSIRLDEELKDRLKTLADDRHRSAHALMLEAITEYIDREEK
                     RSQYLRDGQAAWQHYQETGLHLTAEEAEAWISTWGTENEQDAPPCHR"
     CDS             complement(5061..5279)
                     /locus_tag="ctg1_8"
                     /transl_table=11
                     /translation="MKAFTLTVLAAMFLTPVHAIPLKPVTTLQPTYPVQAAAKRIEGQV
                     TATFDILDDGRVDNVSLTGCHFFFGKR"
     CDS             complement(5276..5647)
                     /locus_tag="ctg1_9"
                     /transl_table=11
                     /translation="MRLIPFILLALCSPLLLTACKHSTTQPPKIYTLDKSSKISSYAAA
                     IKTAVEMQMFEPEAYAGKMCTVRISIQRDGTLNSAIAEGGDPKLCKAAISAVTHAKIPP
                     APDENTWQIFKNAPLDFRP"
     CDS             complement(5921..6166)
                     /locus_tag="ctg1_10"
                     /transl_table=11
                     /translation="MTHLKLTPAEEKRLADAFVAQALAMGLKGNRTLPKAVKQQVRERV
                     LRAIQDEREARRAQEMRREKYEAAETTFTWQPLRRR"
     CDS             6493..8178
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Cloacin"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_11"
                     /sec_met_domain="Cloacin (E-value: 2.1e-110, bitscore:
                     357.5, seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGGDGRGPGNSGLGHNGGQASGNVNGTSGKGGPSSGGGTDPNSG
                     PGWGTTHTPNGDIHNYNPGEFGNGGSKPGGNGGNSGNHSGSSGGGQSSATAMAFGLPAL
                     ATPGAEGLALSVSGDALSAAVADVLAALKGPFKFGLWGIAIYGVLPSEIAKDDPKMMSK
                     IMTSLPADAVTETPASTLPLDQATVRVRQRVVDVVKDERQHIAVVAGRPMSVPVVDAKP
                     TKRPGVFSVSIPGLPSLQVSVPKGVPTAKAPPKGIVAEKGDSRPAGFTAGGNSREAVIR
                     FPKETGQKPVYVSVTDVLTPAQVKQRQEEEKRRQQAWDAAHPEEGLKRDYDKAKAELDA
                     EDKNIATLNSRIASTEKALPGARAAVQEADKKVKEAEANKDDFVTYNPPHEYGSGWQDQ
                     VRYLDKDIQNQNEKLKAAQASLNAMNESLSRDKAALTGAMESRKQKEKKAKDAENKLNE
                     EKNKPRKGTKDYGHDYHPVPKTEDIKGLGELKRGDPKTPKQGGGGKRARWYGDKKRKIY
                     EWDSQHGELEGYRASDGEHLGAFDPKTGKQVKGPDPKRNIKKYL"
     CDS             8188..8445
                     /locus_tag="ctg1_12"
                     /transl_table=11
                     /translation="MGLKLRLTWFDKKTEEFKGEEYSKDFGDDGSVIESLGMPLKDNIN
                     NGEFDLKKEWVPLLQPFFKNQIKPDVDNCYIAFDYRDGNW"
     CDS             8530..8679
                     /locus_tag="ctg1_13"
                     /transl_table=11
                     /translation="MKKVKTIFLFILIVAGFLLAACQANYIRDVQGGTVAPSSSSELTG
                     IAVQ"
     CDS             10162..12105
                     /locus_tag="ctg1_14"
                     /transl_table=11
                     /translation="MFNTDSLAWQWHIPELARQIYPWVSWLYREYYSLAGFFLVIGLFF
                     GLAELWAGRMRFVGLSHKERREYADRYKRDNNRTAPFSVLASLDSPGRMVRARRHVWNY
                     AYWLTGAAGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLV
                     AGVLLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNA
                     LADFSTEQARKQQAVFLGKDEQGQPVLVPRDTWRKTNIQILGLPGSGKSVMATNALIRC
                     VRDFGDAVVYFDPKGDAWAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLVAGFNLS
                     ETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLITKLENVA
                     DLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARDEFRWWP
                     HASIMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPADFVKTTVLD
                     NTPIRWFYRAASQESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQKEARPLF
                     DVNTLQHLPDGFAVMTGLGVARLAFSSPLRVDRREIPLKTFPVLAKTDPLAEYQSEAGR
                     QRPGDDDFAGLY"
     CDS             12105..12695
                     /locus_tag="ctg1_15"
                     /transl_table=11
                     /translation="MALERYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVAQRLGI
                     AAVQPVYRFLDSLVAKGLLVRAKYPVDGRQVSVWGLTPHGVAFSFDEDEPLTDIIPFQP
                     SRVSAAQLPHRLAVQSLRLAMEARGATGWRYLHRIALKGMKVPDALAELDGRTVAFEVE
                     RTVKSRRRYQEVVSGYRGLTLSGTKTHVKGFWS"
     CDS             complement(12790..13650)
                     /locus_tag="ctg1_16"
                     /transl_table=11
                     /translation="MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYI
                     ELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYS
                     PVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRW
                     EPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSA
                     LPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAS
                     LIKHW"
     CDS             complement(13833..14390)
                     /locus_tag="ctg1_17"
                     /transl_table=11
                     /translation="MRLFGYARVSTSQQSLDLQVRALKDAGVKANRIFTDKASGSSTDR
                     EGLDLLRMKVEEGDVILVKKLDRLGRDTADMIQLIKEFDAQGVAVRFIDDGISTDGDMG
                     QMVVTILSAVAQAERRRILERTNEGRQEAKLKGIKFGRRRTVDRNVVLTLHQKGTGATE
                     IAHQLSIARSTVYKILEDERAS"
     CDS             14554..15012
                     /locus_tag="ctg1_18"
                     /transl_table=11
                     /translation="MPVDFLTTEQTESYGRFTGEPDELQLARYFHLDEADKEFIGKSRG
                     DHNRLGIALQIGCVRFLGTFLTDMNHIPSGVRHFTARQLGIRDITVLAEYGQRENTRRE
                     HAALIRQHYQYREFAWPWTFRLTRLLYTRSWISNERPGLLFDLATGWLM"
ORIGIN
        1 acatcgtatt attctccccg gagccactac gctgacccgg ttgatttcag aggtaaggga
       61 aaaggcgacg ttgcgcctgt ggaacaaact ggcactgata ccgtcagccg aacagcgttc
      121 acagctggag atgctgctgg ggccaactga ttgcagccgc ctgtctttac tggaatcact
      181 gaaaaagggc cctgtgacca tcagtggtcc ggcgtttaat gaagcaattg aacgctggaa
      241 aactctgaac gattttggcc tgcatgctga aaacctgagt acactcccgg ctgtgcgcct
      301 gaaaaatctc gcacgttatg ctggtatgac ttcggtgttc aatattgcca ggatgtcacc
      361 gcagaaaagg atggcggttc tggttgcctt tgtccttgca tgggaaacgc tggcgctgga
      421 tgatgcattg gacgttctgg acgccatgct ggccgttatc atccgtgacg ccagaaagat
      481 tgggcagaaa aaacggctcc gctcgctgaa ggatctggat aaatctgcat tggcgctcgc
      541 cagcgcatgt tcgtacctgc tgaaagaaga aacaccggac gaatcgattc gtgctgaggt
      601 gttcagctac atcccaaggc aaaagctggc tgaaatcatc acgcttgtcc gtgaaattgc
      661 ccggccctca gacgataatt ttcatgaaga aatggtggag cagtacgggc gcgttcgtcg
      721 tttcctgccc catctgctga ataccgttaa attttcatcc gcacctgccg gggttaccac
      781 tctgaatgcc tgtgactacc tcagccggga gttcagctca cggcggcagt tttttgacga
      841 cgcaccaacg gaaattatca gtcggtcatg gaaacggctg gtgattaaca aggaaaaaca
      901 tatcacccgc aggggataca cgctctgctt tctcagtaaa ctgcaggata gtctgaggcg
      961 gagggatgtc tacgttaccg gcagtaaccg gtggggagat cctcgtgcaa gattactaca
     1021 gggtgctgac tggcaggcaa accggattaa ggtttatcgt tctttggggc acccgacaga
     1081 cccgcaggaa gcaataaaat ctctgggtca tcagcttgat agtcgttaca gacaggttgc
     1141 tgcacgtctt tgcgaaaatg aggctgtcga actcgatgtt tctggcccga agccccggtt
     1201 gacaatttct cccctcgcca gtcttgatga gccggacagt ctgaaacgac tgagcaaaat
     1261 gatcagtgat ctactccctc cggtggattt aacggagttg ctgctcgaaa ttaacgccca
     1321 taccggattt gctgatgagt ttttccatgc tagtgaagcc agtgccagag ttgatgatct
     1381 gcccgtcagc atcagcgccg tgctgatggc tgaagcctgc aatatcggtc tggaaccact
     1441 gatcagatca aatgttcctg cactgacccg acaccggctg aactggacaa aagcgaacta
     1501 tctgcgggct gaaactatca ccagcgctaa tgccagactg gttgattttc aggcaacgct
     1561 gccactggca cagatatggg gtggaggaga agtggcatct gcagatggaa tgcgctttgt
     1621 tacgccagtc agaacaatca atgccggacc gaaccgcaaa tactttggta ataacagagg
     1681 gatcacctgg tacaactttg tgtccgatca gtattccggc tttcatggca tcgttatacc
     1741 ggggacgctg agggactcta tctttgtgct ggaaggtctt ctggaacagg agaccgggct
     1801 gaatccaacc gaaattatga ccgatacagc aggtgccagc gaacttgtct ttggcctttt
     1861 ctggctgctg ggataccagt tttctccacg cctggctgat gccggtgctt cggttttctg
     1921 gcgaatggac catgatgccg actatggcgt gctgaatgat attgccagag ggcaatcaga
     1981 tccccgaaaa atagtccttc agtgggacga aatgatccgg accgctggct ccctgaagct
     2041 gggcaaagta caggtttcag tgctggtccg ttcattgctg aaaagtgaac gtccttccgg
     2101 actgactcag gcaatcattg aagtggggcg catcaacaaa acgctgtatc tgcttaatta
     2161 tattgatgat gaagattacc gccggcgcat tctgacccag cttaatcggg gagaaagtcg
     2221 ccatgccgtt gccagagcca tctgtcacgg tcaaaaaggt gagataagaa aacgatatac
     2281 cgacggtcag gaagatcaac tgggcacact ggggctggtc actaacgccg tcgtgttatg
     2341 gaacactatt tatatgcagg cagccctgga tcatctccgg gcgcagggtg aaacactgaa
     2401 tgatgaagat atcgcacgcc tctccccgct ttgccacgga catatcaata tgctcggcca
     2461 ttattccttc acgctggcag aactggtgac caaaggacat ctgagaccat taaaagaggc
     2521 gtcagaggca gaaaacgttg cttaacgtga gttttcgttc cactgagcgt cagaccccgt
     2581 atctgttcaa ccgtaaggcg aacggcatcg atgaaatctg gtacatctgc cctgaccggc
     2641 cgacgcttgt ccgggtacag cgggcgattc tggcggtgga tgaaatcgtg aacccgcaga
     2701 ccggcgaggc ccgcaaaacg gcggagctgg accgggagag gctgttcgca tgctttaaat
     2761 ttatgacaac ggagtgaggg attatggcgc tgtacatggt atttattgag gacgtggaag
     2821 acaaagacgg cgagcgctgc attatgccaa ccagcgagca tctggaagac atggcggtca
     2881 tggcctggca gaccggtgca tatgtattca ggtttgaaga tcaggcccag catctggcaa
     2941 tgatgaagtt tatcggcatg tatcacgaac ggctgaacag cgatgacaaa gccacgtatt
     3001 acttcaccgg caaaaatccg gcgtgggaac gtgagaaacc ggccggaatg aagctgtgtg
     3061 attatcttta tcgcaaggtt gagcagttcg ccatcgagaa cggcgtgcag gtactggacg
     3121 ccgggaaata caccccggag cagatcgggg cgatgattga cgtcgtgagt gagcggtacg
     3181 gggaaagcgc ggtgaacgag aagctgaaag cggagctgat gcgggaatat aacagccgct
     3241 attttaacgt tccggtgcca gaactgccgg aggataaacc cgcccgccgg aggtggccgt
     3301 tcggcaaaaa ataaacgcca gcaccggcca tgccggtgct gttattcttc cccgagctta
     3361 tcctgcatca cctgccagag tgtttccgca tcctcgtgca gccgctcgca catgtcggcc
     3421 ggggtatcca tatccagctc gttcagtttc tcgagcaaca gcagcgactg gtccttaatg
     3481 aatttagcca tattgagggc ggttttttcc tgcttcgtca tgttctccat tcccttcggt
     3541 aagttctcag ctaaaccagc cggaccagaa gcgttttttc ttctgtgtca gttctgttgt
     3601 caatctgtcc acttcggcct ggagtttccg gcgctcatca tcgtgctggc ggcgttcttc
     3661 ttctcgggat gttttatctt ccagcatcag ggtgacagcc tgccggagat cggccagttc
     3721 cttttgcatt gccagaagct gttcctgtgg gaaatttttt tgtgtatttt cacggtgtga
     3781 aatgccggga atttgtttct cagggatatt cacatttccg tatacacgga tcagttctga
     3841 cacatccacg acagggttgt ttttcccgtc acgtgacacg gtaacctttc cctgttttac
     3901 atgattgtat agcgttcttc tggtaatgcc cgcggcttgt gctgcctgtg aaaggttgag
     3961 caatgttttc gccactgtat acccctgatt ttatcgggtg tgaaagatgt gtaatttctc
     4021 acggtaaatg tatcgctgaa ttttacccgt ttttccgttc aggatgtggt tttctgacgc
     4081 gctgtgcttg tcaaaccggc gacggccacg caatgaattg cgcccccgtc atcggttatt
     4141 agaggctgtc tgcccccgga tacccggatt ctttctgatg cctgacggtg acgatcacaa
     4201 tccggtccat ttcccggtcg tggcggtaga gcatcacata gccactgtcg ccaaacccga
     4261 tcaccagttc ctgatattcc agcggcagaa atggcaccgg gcggccaatg tctggcaatg
     4321 ttttcagttg ctggatagcc cggacgatca cctcaccggc ttttctggct gccagccgat
     4381 ttttggtttt gagaaagtcc tggaggcgtt gtaaatctcg ctgtgccagc gcggaaatcg
     4441 ttacctgtgg catggcggag catcctgctc gttctcagtt ccccaggtac ttatccaggc
     4501 ttctgcttct tccgcagtaa ggtgcagacc cgtttcctga tagtgctgcc atgcggcttg
     4561 tccgtcccgc aggtactggc tgcgcttctc ttcccggtcg atgtattcgg tgattgcctc
     4621 cagcattagc gcgtgcgctg agcggtgccg gtcatcggcc agcgttttca gccggtcctt
     4681 aagttcttca tcgagcctga tggatgttgc tgatgacata aaagcccctt tgtagtcatg
     4741 tgtaatacat atgactactt taatccgtgg cggcgctatt tgccagaaat acggcttttg
     4801 ctacccattt ttcagcttcg cttccccatt tttcagcttc gcttccacta atcagggctg
     4861 ctacaggctc actcatcatc caggactatt gcagcctgcg ggttaaagga cctgttactg
     4921 gcggcaacca tcatcattga actttttggt ggtggctggt cgcggatcct gtaagccgtc
     4981 atttttcaga ctgaattcaa aatttataac ctgtcgcatt gccgggtgcc ctgcgggata
     5041 tagccagtgc ctcattgccg tcagcgtttc ccgaaaaaaa agtgacagcc ggtaagcgac
     5101 acgttgtcca ctcgtccatc gtccagaata tcaaacgtgg cggtcacctg accttcgatg
     5161 cgttttgctg cggcctgtac cgggtaggtt ggctgcagtg tggttacggg ttttagtggt
     5221 atcgcatgta ccggagtgag gaacatggcc gccagcactg tcagagtaaa agctttcatg
     5281 gtctgaaatc cagaggggcg tttttgaata tttgccaggt attttcatcc ggtgccggcg
     5341 gaattttggc gtgggtaacg gctgatattg ctgctttaca gagtttcgga tctcctcctt
     5401 cagcaatggc gctgttcaga gtgccatcac gttgtatgga tatccgcacg gtgcacattt
     5461 ttcccgcata ggcctctggt tcaaacatct gcatttcaac agcggtcttg atggccgcag
     5521 cgtagctact gattttagat gacttatcca gagtataaat tttcggcggc tgggtggtgg
     5581 aatgcttaca ggccgtcagg agtaaggggc tgcacaatgc cagcaggata aagggtatta
     5641 aacgcatcgg gttgatgacc tgtcagtaaa aaatattaca tgtatatttg ccactcttta
     5701 cggccacgtt cattgacata aacacggctt atcgtatcgt ttttacacca aacggcccgc
     5761 catgcagttg cgtgcatagg catgcagcgg gttacaattt accgggcgcg tttccggcgg
     5821 ttttccgggt gatttgttgc ctgttttatc ccgtagccgc cggaaacgct ctgagggctt
     5881 ctcgggcggt gctgataacg ggttttatgg taaatacccc tcaccggcgg cgcagcggct
     5941 gccaggtgaa ggtggtttcc gccgcctcgt atttctcccg acgcatttcc tgcgcccgcc
     6001 tggcttcacg ttcgtcctga atggcgcgaa gcaccctttc ccgcacctgc tgttttaccg
     6061 cctttggcag cgttctgttc cctttcaggc ccatggccag tgcctgagcg acaaaggcgt
     6121 ccgctaggcg cttttcttca gcgggagtca gtttcaggtg tgtcatggtg gcctccgggc
     6181 gtctcaggtt tcctgaacag tttaaccgcg ggtcctcccc tcataccagt tagctttcag
     6241 atgtgtctat accacctgaa atgtaagtgt gatgtacatc tcaaataata aaatttgttg
     6301 ccgtgagaaa ttttcgggaa aagacgcgat ctgcttacag gtggctccgg gcgctttttt
     6361 gtgcctgaag atgagaacta atctcatata ttgacacctg aaaacgggag gagtaaggta
     6421 ataattatac tgtgtatatg tacagtatat tggctttaat ttattgtttt aaatgtcaaa
     6481 gaggaaaacg atatgagtgg tggagacggt cgaggtccgg gtaattcagg tctgggacat
     6541 aatggtggtc aggccagtgg gaatgtgaac ggtacgtctg gtaaaggtgg cccttcatca
     6601 ggtggtggta cggatccaaa cagcgggccg ggctggggta cgacgcatac gccgaatgga
     6661 gatattcata actataatcc gggggagttt ggtaacggcg ggagtaaacc cggtggtaat
     6721 ggtggtaaca gcggcaatca tagcggtagc tctggtggcg gacagtcttc ggccactgcg
     6781 atggccttcg gtctgcctgc cctggctact ccgggggctg aaggactggc tttatcagtt
     6841 tccggcgatg cgttgtcggc cgccgttgct gatgtgctgg ctgccctgaa ggggccgttt
     6901 aagtttggtc tgtgggggat tgcgatctac ggtgtgctgc cttctgagat tgcaaaagat
     6961 gatccgaaaa tgatgtcaaa aattatgacg tcattaccgg ccgatgcggt gacggagact
     7021 ccggcaagta ctttaccact ggaccaggcg acggttcgtg tcagacaacg ggttgtggat
     7081 gtggtgaagg atgagcggca gcatattgcg gttgtcgcag gtcggccaat gagtgtccct
     7141 gtggtggatg cgaaaccgac aaaacgtccg ggggtattca gtgtgtcgat tccgggtctc
     7201 ccgtctctgc aggtgagcgt accgaaaggt gttccgacag cgaaagcccc gccaaaaggc
     7261 attgttgctg aaaaaggtga ttcacgtccg gctggtttta cagccggtgg taactcccgt
     7321 gaggccgtta ttcgtttccc gaaagagacc ggacagaagc cggtttatgt gtcggtgaca
     7381 gatgttctta ccccggcaca ggtaaaacag cgtcaggagg aagaaaagcg tcgccagcag
     7441 gcatgggacg ccgctcatcc ggaagagggg ctgaaaagag actatgataa agcgaaagct
     7501 gagctggatg ccgaagataa aaatattgcg accttaaaca gccgcattgc atcgacagag
     7561 aaggcgctcc ccggtgcaag ggctgctgtt caggaagccg ataaaaaggt aaaagaggca
     7621 gaggcaaata aagatgattt tgtgacttat aacccgcctc atgaatatgg ctccgggtgg
     7681 caggatcagg ttcgctatct tgataaggat attcagaatc agaatgagaa attaaaagcg
     7741 gctcaggcat ctttaaacgc aatgaatgaa tccttatcca gagataaggc tgcacttacc
     7801 ggggcgatgg agagccggaa acaaaaggag aaaaaagcga aggatgcaga aaataagtta
     7861 aatgaggaaa agaacaagcc tcgcaagggg actaaagact acggccatga ttatcatcca
     7921 gtacctaaaa cagaagacat aaagggactt ggagagttaa agcgaggtga tcctaaaaca
     7981 cctaaacaag gtggtggtgg taagcgggcc cgatggtatg gcgataaaaa acgtaaaatt
     8041 tatgaatggg attcccagca cggtgagctt gaagggtatc gtgccagtga tggcgaacac
     8101 ctcggggcat ttgatcccaa aacgggtaag caggttaaag ggccagatcc aaaacggaac
     8161 attaaaaaat atctttgaga ggtaaatatg gggcttaaat tacgtttgac atggtttgat
     8221 aagaaaactg aagagtttaa aggggaagag tattctaaag actttggtga cgatggttct
     8281 gtcattgaaa gcttgggaat gcctttaaag gataatatta ataatggtga gtttgatttg
     8341 aagaaagaat gggttccttt actacagcca ttttttaaaa atcaaataaa acctgatgtg
     8401 gataattgtt atatagcttt tgattatcgg gacggtaact ggtaacaaaa aattatcaag
     8461 gatgatttga aatactgact tccggtgttc agggatgaat gccggagtct ttaaatacag
     8521 ggaaagtata tgaaaaaggt aaagactatt tttcttttta tattgattgt tgctggcttt
     8581 cttctggccg catgtcaggc aaattatatc cgggatgttc agggcggaac ggtggcacca
     8641 tcgtcctcct ctgaactgac ggggatcgcg gttcagtaga aaagatcaaa ggatcttctt
     8701 gagatccttt ttttctgcgc gtaatctttt gccctgtaaa cgaaaaaacc acctggggag
     8761 gtggtttgat cgaaggttaa gtcagttggg gaactgctta accgtggtaa ctggctttcg
     8821 cagagcacag caaccaaatc tgtccttcca gtgtagccgg actttggcgc acacttcaag
     8881 agcaacctcg tgtttagcta aacaaatcct ctgcgaactc ccagttacca atggctgctg
     8941 ccagtggcgt tttgcgtgct ttcccgggtt ggactcaagt gaacagttac cggataaggc
     9001 gcagcagtcg ggctgaacgg ggagttcttg cttacagccc agcttggagc gaacgaccta
     9061 caccgggccg agataccagt gtgtgagcta tgagaaagcg ccacacttcc cgcaagggag
     9121 aacggcggac aggtatccgg taaacggcag ggtcggaaca ggagagcgca agagggagcg
     9181 acctaccgga aacggtgggg atctttaagt cctgtcgggt ttcgcccgta ctgtcagatt
     9241 catggttgag cctcacggct cccacagatg caccgaaaaa gcgtctgttt atgtgaactc
     9301 tggcaggagg gcggagccta tggaaaaacg ccaccggcgc ggccctgccg ttttgcctca
     9361 catgctcgtt ccctgcttat ccacggaatc tgtgggtaac tttgcgagag ttcgcagcgc
     9421 ccgccgcagt ctcacggccg gcgcgtagcg accgagtgag cgaggaggcg caatttcccc
     9481 ggcacctgca agacggtcac cggacgcgtg gatgtgacat attgctccgt gttaccgcct
     9541 ttctcttccc tgccgataaa ttattcagat aggtgaagtc tgtcggtttt ctgctgaata
     9601 ttttacgtta acctatctct gttgcttttt tctccttgcg gagaaatgca cgtcatcccc
     9661 gctggggcgt gactgacttc agggggaaat cccctgctta cgctggctgg acgccaccga
     9721 cgcactgtct ttccccctct ttctggctct gtccggctgg acgccggtca cgccagaaat
     9781 tcacccggcc cccgtcaggc tcacgcctga ccacccacaa aatccacggt gctggacgca
     9841 cctgacgaag cagcaaagct gctcctgatt ttgcgggtgg tcagccgctc gctatggcga
     9901 actctgacgg gggccggaac accggaaaag accgcactgg ggtgccgcct tttcctctca
     9961 cacgctgggg cgtgctcgtt gttcctccgg ggctgcgcct tttccgcatg gggcggaaag
    10021 aggctggcct ccgcggtgaa agctgaacgc aatcaccacg gacgtgaccg ccgccgccat
    10081 gccttggggc atgtccgcgg cttgtgcagc aggggctgca caacacgccg gtaaacccgt
    10141 cgtctgaagg agagagattg catgtttaat acggattcgc ttgcctggca gtggcatatc
    10201 ccggagctgg cccggcagat ttacccgtgg gtcagctggc tgtaccggga gtattacagt
    10261 ctggccggtt tttttctggt tatcggcctg tttttcggtc tggcagaact ctgggccggg
    10321 cggatgcgat tcgtggggct gagtcataag gagcggcggg agtatgccga tcgctataag
    10381 cgcgataata accggactgc gccattttcg gtgctggcct cgctggattc gcccgggcgg
    10441 atggtcaggg cacggcgaca tgtctggaac tacgcatact ggctgaccgg cgctgccggt
    10501 ctggcccttc tgggggggct ggttgtcgcc gtgtttatcg agagctgggg agaaaccgtc
    10561 ctgcgtccgg acctctacgc gaacgcagat tattacctgc tgcagccggc taacctgttc
    10621 gggattgcct ggtgtgccgg aggtcttgtc gcaggcgtcc tcctggcgcg gctgctggcg
    10681 ttcctgctgc ttgacgggca ttttgcggcc gctgacgagg cggtgaacgc gaaactgaat
    10741 caggagagcc ggcgcagcag ccagcggacc ggagaaatga ccgacgtccg ccacctgcat
    10801 ttcggggagc cggtaccggt taacgcgctg gccgattttt ccacggagca ggcccggaaa
    10861 cagcaggcgg tgtttctggg taaggatgag cagggccagc cggtgctggt cccgcgtgat
    10921 acctggcgca agaccaacat tcagatcctc ggcctgcccg ggagcggcaa gagcgtgatg
    10981 gccaccaacg cgctcattcg ctgcgtacgc gatttcgggg acgcggtggt gtacttcgac
    11041 ccgaaagggg acgcgtgggc gcactgcccg gacttcaccc tgctggatct gcggccgggg
    11101 aaaccggcgc agctgaatct gttccgcgat ctcgaccagt acgccctgaa gaatcttctg
    11161 gttgccggat ttaacctgag tgagaccggc gacgtggcgg accactaccg catcagcgag
    11221 cagaaagcgg cgaagctgat tgcggagcag tttccgcagg gggcaaatat tcagcaggtg
    11281 ctggcggcgg cgtacgcact gccggaggcc ctgaaaaagg acgtgaaggg gctgatcacc
    11341 aagctggaga acgtggccga cctgagcgtc cttcagacgg acagcggcat cgacgtggcg
    11401 gggataatca acggcggcgg ctgcctgtac gtcatcggct cgatggacga tgaggcggtg
    11461 atccgggtgc agaagatgct gtttgcccgc tgcgcgcaaa tcatcattgc gcgggacgag
    11521 ttccggtggt ggccgcacgc gagcatcatg ctcgatgaga ttaaatatct gctgtcgaag
    11581 tacgtgctga acgcgctggg gacgctgcgc agccgggact gcaacctgct gctcgcgcac
    11641 cagtcgctgg gcgacttcgg ccagtgcggg caggatctgc ccgctgattt tgtgaaaacc
    11701 acggtactgg ataacacgcc gatccgctgg ttctaccggg cggccagcca ggagtccgct
    11761 cagtgggcgg ccggacagac cggggagatc cgggtggacg tggagcgccg ccgggccagc
    11821 cgggaggcgg ggaacgtgga gcatatcagc ggggacagct tcatccagaa ggaggcgcgg
    11881 ccgctgtttg acgtgaacac cctgcaacat ctgcctgacg ggttcgcggt gatgaccggg
    11941 ctgggcgtgg cgcggctggc gttcagcagc ccgctgcgtg ttgatcgccg ggaaattccg
    12001 ctgaaaacct tccctgtgct ggcgaaaacg gacccgctgg cggagtacca gtcggaggcc
    12061 gggcggcagc ggccgggtga tgatgatttt gcggggctgt actgatggca ctggagcgat
    12121 acaacgtcag ccacgcgaag cggcaggcac ggaacgcgga gaaaacacgg ctgaccctgc
    12181 gctggctgcg ggaagaactg tgttccacgg cggagctggt tgcgcaacgg ctggggattg
    12241 cggcggtaca gccggtttac cgcttcctgg acagcctggt ggcgaaaggg ctgctggtcc
    12301 gggcgaaata cccggttgac ggccgtcagg tcagcgtgtg ggggctgacg ccgcacgggg
    12361 tggcgttctc gttcgacgag gacgagccgc tgacggacat tattccgttt cagccgtcgc
    12421 gggtgtcggc ggcgcagctg ccgcaccggc tggccgtgca gtccctgcgc ctcgccatgg
    12481 aggcccgggg ggccaccggc tggcggtacc tgcaccgtat tgccctgaaa gggatgaagg
    12541 tgccggacgc gctggcggag ctggacggca gaacggtggc gtttgaggtg gaacgtaccg
    12601 tcaagagccg tcgccggtat caggaagtgg tgtccgggta tcggggtctg acgctcagtg
    12661 gaacgaaaac tcacgttaag ggattttggt catgagatta tcaaaaagga tcttcaccta
    12721 gatcctttta aattaaaaat gaagttttaa atcaatctaa agtatatatg agtaaacttg
    12781 gtctgacagt taccaatgct taatcagtga ggcacctatc tcagcgatct gtctatttcg
    12841 ttcatccata gttgcctgac tccccgtcgt gtagataact acgatacggg agggcttacc
    12901 atctggcccc agtgctgcaa tgataccgcg agacccacgc tcaccggctc cagatttatc
    12961 agcaataaac cagccagccg gaagggccga gcgcagaagt ggtcctgcaa ctttatccgc
    13021 ctccatccag tctattaatt gttgccggga agctagagta agtagttcgc cagttaatag
    13081 tttgcgcaac gttgttgcca ttgctgcagg catcgtggtg tcacgctcgt cgtttggtat
    13141 ggcttcattc agctccggtt cccaacgatc aaggcgagtt acatgatccc ccatgttgtg
    13201 caaaaaagcg gttagctcct tcggtcctcc gatcgttgtc agaagtaagt tggcagcagt
    13261 gttatcactc atggttatgg cagcactgca taattctctt actgtcatgc catccgtaag
    13321 atgcttttct gtgactggtg agtactcaac caagtcattc tgagaatagt gtatgcggcg
    13381 accgagttgc tcttgcccgg cgtcaacacg ggataatacc gcaccacata gcagaacttt
    13441 aaaagtgctc atcattggaa aacgttcttc ggggcgaaaa ctctcaagga tcttaccgct
    13501 gttgagatcc agttcgatgt aacccactcg tgcacccaac tgatcttcag catcttttac
    13561 tttcaccagc gtttctgggt gagcaaaaac aggaaggcaa aatgccgcaa aaaagggaat
    13621 aagggcgaca cgaaaatgtt gaatactcat actcttcctt tttcaatatt attgaagcat
    13681 ttaccagggt tattgtctca tgagcggata catatttgaa tgtatttaga aaaataaaca
    13741 aataggggtt ccgcgcacat ttccccgaaa agtgccacct gacgtctaag aaaccattat
    13801 tatcatgaca ttaacctata aaaataggcg tatcacgagg ccctttcgtc ttcaagaatt
    13861 ttataaaccg tggagcgggc aatactgagc tgatgagcaa tttccgttgc accagtgccc
    13921 ttctgatgaa gcgtcagcac gacgttcctg tccacggtac gcctgcggcc aaatttgatt
    13981 cctttcagct ttgcttcctg tcggccctca ttcgtgcgtt ctaggatcct ccggcgttca
    14041 gcctgtgcca cagccgacag gatggtgacc accatttgcc ccatatcacc gtcggtactg
    14101 atcccgtcat caatgaaccg gactgccacg ccctgagcgt caaattcctt tatcagttgg
    14161 atcatatcgg cagtgtcgcg gccaagacgg tcgagcttct taaccagaat gacatcacct
    14221 tcctccacct tcatcctcag caaatccagc ccttcccggt ctgttgaact gccggatgcc
    14281 ttatcggtaa atatacggtt tgctttcaca cctgcgtctt tgagtgctct gacctgaaga
    14341 tcaagagact gctgactggt tgagacccga gcgtaaccaa aaagtcgcat aaaaatgtac
    14401 cttaaatcga atatcggaca actcatgtct attattacaa atttacgatt taatagacat
    14461 attaatgtaa cagttttacg atgtccgata atttataaca tttcgtacgg ttggaaaaat
    14521 gttactaaat gcccgtcagg cagggaggcc gatatgcccg ttgactttct gaccactgag
    14581 cagactgaaa gctatggcag attcaccggt gaaccggatg agcttcagct ggcacgatat
    14641 tttcaccttg atgaagcaga caaggaattt atcggaaaaa gcagaggtga tcacaaccgt
    14701 ctgggcattg ccctgcaaat tggatgtgtc cgttttctgg gcaccttcct caccgatatg
    14761 aatcatattc cttccggcgt ccggcatttt accgccagac agctcgggat tcgtgatatc
    14821 accgttcttg cagaatacgg tcagagggaa aatacccgcc gtgagcatgc agcgctgata
    14881 cgtcagcact atcagtatcg tgaatttgcc tggccctgga catttcgcct tacccgtctt
    14941 ttatataccc ggagctggat aagcaacgaa cgtcctggcc tgcttttcga tctggcgaca
    15001 gggtggctta tgca
//
