LOCUS       NZ_CP121495.1          17668 bp    DNA              UNK 01-JAN-1980
DEFINITION  NZ_CP121495.1 Staphylococcus epidermidis strain 24FSE03 plasmid
            unnamed7, complete sequence.
ACCESSION   NZ_CP121495
VERSION     NZ_CP121495.1
KEYWORDS    .
SOURCE      .
  ORGANISM  .
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-06-07 14:42:09
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             3..131
                     /locus_tag="ctg1_1"
                     /transl_table=11
                     /translation="MKQLKDINGGRETGCSGDFVEDGIMCNIGQGIGKAINKVRGK"
     CDS             152..301
                     /locus_tag="ctg1_2"
                     /transl_table=11
                     /translation="MKTLNEKQLKDINGGKGIVGEVTGEVTSIGNAISNGWHDLKQSVA
                     DTTK"
     CDS             complement(424..645)
                     /locus_tag="ctg1_3"
                     /transl_table=11
                     /translation="MAKYWKENQEGLLNDGEALTILMMLYNEHPYVVQLPCLNKQLQDD
                     NRYAQPTYTIYSTTKNRKENKRRIKNSI"
     CDS             complement(728..913)
                     /locus_tag="ctg1_4"
                     /transl_table=11
                     /translation="MQNTYIKKWVSLSSIISYSIEIFKCLYSEFSFPLNDVLLEGTDKK
                     ASKEYINKNQKTFYCL"
     CDS             complement(1297..1644)
                     /locus_tag="ctg1_5"
                     /transl_table=11
                     /translation="MSYENACDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKISVASTSHHLRLLYKNDVLDFYKKGKMAYYFIKDDEI
                     KEFFSKNQEGF"
     CDS             complement(1663..2280)
                     /locus_tag="ctg1_6"
                     /transl_table=11
                     /translation="MIQTIVTAAILYIATAVDLLVILLIFFARAKTKKEYRDIYIGQYV
                     GSVALIVVSLFFAFVLNYVPEKWILGLLGLIPIYLGIKVAIYDDCEGEKRAKKELNEKG
                     LSKLVGTVAIVTIASCGADNIGLFVPYFVTLSVTNLLITLFVFLILIFFLVFTAQKLSN
                     IPGVGEIVEKFSRWIMAVIYIALGLFIIIENDTIQTILGFIF"
     CDS             complement(2514..2963)
                     /locus_tag="ctg1_7"
                     /transl_table=11
                     /translation="MQEQVKASQLITDDYEYIKSGKALKDFEEKNKRLEDRLLDEQIKN
                     GKVIDEYNDLADSYNNLLEQNQEKEKELNRSYKLFNNVFKLIKGVMKEETYHSLINHID
                     NHLESSKMRETMIVDDNDEQFFKKKYQRHEPEIIFEDERDDGYTL"
     CDS             complement(3052..3783)
                     /locus_tag="ctg1_8"
                     /transl_table=11
                     /translation="MAYSIIRVAKVKSKTNTKGIQKHVQRQNKNYENMDIDLEKSYLNY
                     DLVNDSPIDYNQKIEEKIEQNYNGKRKIRKDAVKHIDGLITSGNEFFKNQTLEETKQFF
                     EHAKTFLEQEYGKDNLLYATVHMDEKTPHMHYGVVPITEDGRLSAKEVLGNKKALTEFQ
                     DRFNEHINSCGYDLSRGITRGVTPRRHEQISRYKNLTDYHKEEYEHESRKLDRIKQESE
                     EVMEQVSKCFRCSKKAYKCPI"
     CDS             complement(3969..5348)
                     /locus_tag="ctg1_9"
                     /transl_table=11
                     /translation="MFSLYKKFKGLFYSVLFWLCILSFFSVLNEMVLNVSLPDIANHFN
                     TTPGITNWVNTAYMLTFSIGTAVYGKLSDYINIKKLLIIGISLSCLGSLIAFIGHNHFF
                     ILIFGRLVQGVGSAAFPSLIMVVVARNITRKKQGKAFGFIGSIVALGEGLGPSIGGIIA
                     HYIHWSYLLILPMITIVTIPFLIKVMVPGKSTKNTLDIVGIVLMSISIICFMLFTTNYN
                     WTFLILFTIFFVIFIKHISRVSNPFINPKLGKNIPFMLGLFSGGLIFSIVAGFISMVPY
                     MMKTIYHVNVATIGNSVIFPGTMSVIVFGYFGGFLVDRKGSLFVFILGSLSISISFLTI
                     AFFVEFSMWLTTFMFIFVMGGLSFTKTVISKIVSSSLSEEEVASGMSLLNFTSFLSEGT
                     GIAIVGGLLSLQLINRKLVLEFINYSSGVYSNILVAMAILIILCCLLTIIVFKRSEKQF
                     E"
     CDS             6189..6758
                     /locus_tag="ctg1_10"
                     /transl_table=11
                     /translation="MKKMLRISIFIIVVSIFIVFKYSYQIEGILEEYPNILKAFVALFT
                     LLTTVISLVIAYKSYDNSVKQQEKDKEEKNKQFEENSDRIINSLKSDLAKYTRKINVFR
                     LGYTNSDVEFSELAKELSIKSNLEEIEKLTSQVRSSKSTELAKMDEVNIVNLHTASDSA
                     LFLFDIYENTSRENDGFCCKLENHII"
     CDS             complement(6924..7460)
                     /locus_tag="ctg1_11"
                     /transl_table=11
                     /translation="MISNKLKSARLAKELTQSEVAKKLYVTRQTVSRWEQGKTLPNIYV
                     IQELSDLYDISLDELVVNTALENKEAKSMKNVNPFALFGAILFNVFLFSLIVIFFGGFL
                     LLSLFISLAMLFSPLILAIFVLTGVQEFNVIQLVMTVIFVVIGLLSIPLLKKVSVFLFK
                     FFKRYLKFNHKAIFY"
     CDS             8007..8255
                     /locus_tag="ctg1_12"
                     /transl_table=11
                     /translation="MNLKINNKIIIEYDIEQKVFSQFQKVKQMNELLRLLLSDFIFDIN
                     TKSNRINRIWIKKSILFIGLTTTEAYEINKNNSIQTI"
     CDS             complement(9028..9138)
                     /locus_tag="ctg1_13"
                     /transl_table=11
                     /translation="MSTKKKIKVTLAMINVLLTAVELYLQWQLSKSENEL"
     CDS             complement(9306..10241)
                     /locus_tag="ctg1_14"
                     /transl_table=11
                     /translation="MPNFEKYNLSQVKTERFYQLPKYLFEDAYFKKMSAEAKIMYALLK
                     DRFELSIQNEWVDKNNNIYFIFSNKHLCEYLGYAEQKIIKLKKELISFNLLTQERVGLN
                     KPNRLYLLKPNYDIKASHSKELPNSQFQNNEFGSSRTVNLSGQELPNSQSNDTENNDTD
                     YIKTESNDTNDLNDNKLTFPSNHTNHSNHNNSNFNNEALKFQLLEELPQSIQRYLSNFS
                     VNEIKIIKPVLLKAKTSFNNSIDTYYLLEDMEIEILHVLKRFKAMLIQKNETVEAMQGY
                     LMKSLKSEFAEMHTLNKRRDHLPITSLFNQ"
     protocluster    10341..17668
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[15340:17500]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      15341..17500
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    10341..17668
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          10341..17668
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             10681..11448
                     /locus_tag="ctg1_15"
                     /transl_table=11
                     /translation="MRTIKMVADELGVTKQTIVNNAKSLNITFEKENGINYIDDNDYLK
                     IIEKITKKESTIQNKESVKKELFGENTAKSEKNIYNNSNSSETLKTKVNELEKQIEIFE
                     TRAKNDEKYIENLTKQLDQQNSNVNTLNKLLENQQILALESNKKIQKLESQLEEERQLN
                     YSFDTATNNRQNINPQEATFTEESQNINQQQTKRQPTEVNYKDIAEEKKNDSTDEGELT
                     KEDKFVEETKSDPDDNREVEPSKKGFWSRFFGN"
     CDS             11674..12159
                     /locus_tag="ctg1_16"
                     /transl_table=11
                     /translation="MFAIFVALISLTSVWVGYKIDNSMKRKSEIEDSRINWIQKVREVN
                     TNLIKAFYDFNTHQNFYSEKTKDINMLDNMRSTLLEGLEYESRKRDNNAEKYKEEIDNI
                     QEKVKEQTKVLNNKKIDRTSAMYNLFTSIEVMKNLFPINKYDIHKVRIEHKKNTSCS"
     CDS             12107..12361
                     /locus_tag="ctg1_17"
                     /transl_table=11
                     /translation="MIFIKYESNIKKILVAVESSASFYKGDLSISNEKIYDSLNELKKN
                     IRESYDGNNTLEETKIDEYKDFINNYLKIEWEKVKSRKT"
     CDS             12640..12792
                     /locus_tag="ctg1_18"
                     /transl_table=11
                     /translation="MITGSIATYFLKNNEKSNIKESLKHDIDNIENLSNNDIERLIKII
                     KTYRD"
     CDS             12901..14223
                     /locus_tag="ctg1_19"
                     /transl_table=11
                     /translation="MKKSLEEINGKVSFDSEANGIKKLIMYLGPGLLVAVGYMDPGNWI
                     TSMAGGAQFGYTLLFIILLSSLSAMLLQSMCARLGIASGMDLAQVTKHISNKPLSIAAW
                     IVTELAIMATDIAEVIGSAIALNLLFDIPLVVGVTITVLDVLLLLLIIKFGFRKIEAIV
                     GVLIFTVLFIFVFEVYFASPEWSAVLGGFIPSTEIATNKGVLYMALGIIGATIMPHNLY
                     LHSSIVQSRNYIRESKAKKKEAIKYAIIDSHIQLSIAFIINCLILILGAALFFGNGEDL
                     GRFYDLYNALQESEFAGAIGGAVMSTLFAIALLASGQNSTITGTLSGQIVMEGFLNIKI
                     PQWARRLVTRLIAVIPVFICLWLYGSSTSKIEDLLIFTQVFLSLALPFSIIPLTLATNN
                     PKIMGKEFTNKTWINIIAWVLTIILSILNIYLIIETFNEFL"
     CDS             complement(14499..15116)
                     /locus_tag="ctg1_20"
                     /transl_table=11
                     /translation="MIIGYARVSSIDQNLERQLDNLKTFGVEKIFTEKQSGKSVENRPV
                     FQEALNFVRMGDRFVVESIDRLGRNYDEIIETVNYLKEKNVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGRPLLYSPNAKDPQKRV
                     IYHRVVEMLEEGQAISKIAKEVNITRQTVYRIKHDKGIILIN"
     CDS             15341..17500
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="resistance (resist) ABC_efflux (Score:
                     251.8; E-value: 8.1e-77)"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 283.5; E-value:
                     5.8e-86)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_21"
                     /sec_met_domain="Peptidase_C39 (E-value: 2.3e-40, bitscore:
                     128.0, seeds: 36, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR01193 (E-value: 4.4e-190, bitscore:
                     623.9, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMAIKFIRQYDEKDCGPTCLAMISQFYGKRVSIPRLREYAKTDKL
                     GTNLYGLVQAGKKIGIELTGVKADSFDDLKQAQLPVMVHIINQQGYDHYIIIEKIKNNT
                     LYIVDPAKGKYKLSSTEFGKYWTNIAVLIDKTDDFTTDNESPSYLNIFIDIFKNNYGKL
                     LFIAFISLFINIVGIVGALYFKLLTDHIIPSNVLKNLHIISFGILLLYIINALINYLRF
                     QLILHLSLKIDVNLMKDYFYHVLHLPMNFFDTRKSGEILQRFMDTSKIREALSSSTVTL
                     LVDTFMIIIGAILLYMQSPLLLLITIIFIPCFIICSYTLRKPFEKYNQKVAEKDAELSS
                     YLIESFDGSNTIKSYQSEDDRFYIGTTKFNGIIENLLKLGRFSNIQLTVNNFLKLTISL
                     VILWLGSYLVMTDSMTLGSLLAFNALTIYYLDPIERLINIQPTLQSSFVAARRIAEITD
                     LETETELYTSKQPYTFKNNIRIENVNFQYGFRSVVLKDINLNIKKGQKVAIVGESGSGK
                     STIGKLLNRYYTASEGNIMIDNYIIDDIDLSDLRKNIGYVSQNTFLFADTIKNNLLHGS
                     NKYKSDEDIVKACQLAESLDFIQKFPDQFNTMLEKEGANLSGGQGQRLSLARTFLKDPD
                     IYIFDEATSALDSLTENKIMEHIDLLTQHGKTVIIISHKLSTIKNADNIYVLNEGQIAE
                     NGTHDELIHLNGIYKNLWQLQMKID"
ORIGIN
        1 atgaaaaaca attaaaagat atcaatggtg gtcgtgaaac tggttgttct ggtgattttg
       61 tagaagatgg aataatgtgc aatatcggac aaggtattgg taaagcaatt aataaagtac
      121 gaggaaaata atttaaagga ggactatttc aatgaaaaca ctaaatgaaa aacaattaaa
      181 agatatcaat ggtggtaaag ggattgttgg tgaagtcact ggcgaagtca ctagtattgg
      241 taatgccatt tcaaatggtt ggcatgattt aaaacagtct gtcgctgata ctacaaaata
      301 ggactcatta tttaaattaa aaaagtctgg gtaataaccc agactttttt aattgttcga
      361 ctttaaataa ttaaattatc tatatattat tttaatataa caaaattaat tatcttatta
      421 aggttatatg ctatttttta ttcttctttt attctctttt ctgtttttgg ttgtagaata
      481 tatagtatac gtgggttgag cgtatctgtt gtcatcttgt agttgcttat ttaaacacgg
      541 taattgtact acatatggat gctcattata taacatcatt aatatagtta atgcttcccc
      601 atcatttaat aatccctctt gattttcttt ccaatattta gccatttttg catcttttat
      661 ttttttaata accaatgata ctgtttgcaa ttatcgaagt tactagtaaa aagaaagtaa
      721 tagatgatta tagacaataa aaagtttttt gattcttgtt tatatattct ttactcgctt
      781 ttttatcagt accttctagc aatacatcat ttaacggaaa actaaattct gaatacaaac
      841 acttaaatat ttctatacta taacttatga tactactcaa agatacccat tttttaatat
      901 aagtgttttg cattcttcta ctaaccagtg ttataattta gacaacaaga gcttcgtaca
      961 ttatatgcac caatcccctc actactcgca atagtgaggg gatttttagg tgttggctaa
     1021 tatcgcctat tttttcttat tgttacgtgt acgtagccaa tgcgtaaata acgcaacaat
     1081 acaaccactg atgactgtgg tcgtgatgtg aacaagagct tcgaccatct gatatgcacc
     1141 tcctctctgc gtctaaattg acgcctgaga gataggcgac ctgtatatta tatcatctct
     1201 gaataaggga taatagataa cttccgataa gtcattttat gttatatctt tgctttttta
     1261 tagtatcaag acaagaagaa actcgtttca ctcgtttcaa aaaccctcct gatttttaga
     1321 gaaaaattct tttatttcat cgtctttaat aaaataatat gccatctttc cctttttata
     1381 aaaatcaagt acatcatttt tatataaaag tcttaaatga tgtgaagttg aagcaacact
     1441 tattttcaat atcaaagaaa tatcacaaac acacaactca tcttctttaa tcaaagataa
     1501 tatgattttc aatttcttct catcacaaat tttttctaaa atgttaagta atttcttaga
     1561 tttatcatct tctaaaaaac ttaaagcatt gttaacttta tcctcatgta cacagatcac
     1621 atcacaagca ttttcataac tcatataaaa tcgcacccta aattaaaata taaatcctaa
     1681 aattgtttga atagtatcat tttcaataat aataaataaa cctaaagcta tataaataac
     1741 agccataatc caacgactaa atttctcaac aatttctcca actcctggaa tattagataa
     1801 tttttgtgca gtaaatacca agaagaaaat taaaattaaa aagacaaaca gagtaattaa
     1861 taaattagta acacttaatg tcacaaaata cggaacaaat aaaccaatat tatcagcacc
     1921 acaacttgct atcgtaacaa ttgcaaccgt accaactaat ttagacaatc ctttttcatt
     1981 caattctttt ttagctctct tttctccttc acaatcatca taaatagcta ctttaattcc
     2041 taaataaatc ggtattaacc ctaataatcc taatatccat ttttcaggaa cataatttaa
     2101 gacaaaggca aagaataaac ttacgacaat caatgccaca gatcctacat attgaccaat
     2161 ataaatatct cgatattctt tcttagtctt tgctctagca aaaaatatta ataaaatcac
     2221 taataaatct actgctgtcg caatataaag aatagcagca gttacaatag tctgaatcat
     2281 aattacacct cattcaaaaa tatttttgaa tgtattataa cttatgtttt caaataatca
     2341 tagatgcttt attccaattg ctttattgac gttgagcctc ggaaccctta acaatcccaa
     2401 aacttgtcga atggtcggct taatagctca cgctatgccg acattcgtct gcaagtttag
     2461 ttaagggttc ttctcaacgc acaataaatt ttctcggcat aaatgcgtcg tctttataaa
     2521 gtgtagccat catctcgttc atcttcaaaa ataatttctg gttcatgcct ttgatatttt
     2581 ttcttaaaga attgttcatc gttatcatct acaatcattg tttctcgcat ttttgagctt
     2641 tctaagtgat tatcaatatg gttaatcaac gaatgatatg tttcttcttt catcacacct
     2701 ttaatcaact taaacacatt gttaaatagt ttatacgaac ggtttaactc tttttctttt
     2761 tcttgatttt gttccaataa attattataa ctatccgcta aatcattgta ttcatctatt
     2821 acttttccat ttttaatctg ttcgtctaat aatctatctt ctaatctttt gtttttttcc
     2881 tcaaaatctt ttaaagcttt tccgctttta atatattcat aatcatcagt aatgagttga
     2941 gaagctttta cttgttcctg caataaatca aattcatttt tatcaataac gacgttacct
     3001 gtttcctgtg tttctttgtt gaacagtcca ccaacttttt cagtttcaag ctcatatggg
     3061 acatttatag gcttttttag aacatctaaa gcattttgat acttgttcca ttacttcttc
     3121 gctttcttgc tttatacggt ctaattttcg gctctcatgc tcatattctt ctttgtgata
     3181 atctgttaaa tttttataac gacttatctg ctcatgtcgt ctcggtgtaa cgccccttgt
     3241 tatacctcta ctcaagtcat aaccacaact attgatatgt tcgttaaatc tatcttgaaa
     3301 ttcagttagt gcctttttat tacctaaaac ctctttcgca ctcaatcgac catcttctgt
     3361 aatcggaact accccataat gcatatgagg tgttttttcg tccatatgca ctgttgcata
     3421 taataaatta tcttttccat actcttgttc taaaaacgtt ttagcatgtt caaaaaactg
     3481 ctttgtttct tcaagtgttt gatttttaaa aaattcatta ccagatgtaa ttaaaccatc
     3541 aatatgtttt actgcgtctt ttctaatttt gcgtttccca ttataatttt gttcaatttt
     3601 ctcttcgatt ttttgattat aatcaatcgg actatcattg actaaatcgt aatttaagta
     3661 tgatttttct aaatcaatat ccatattttc ataattttta ttttgtcttt gtacatgttt
     3721 ttgaatgcct tttgtattcg tttttgattt cactttagca actctgataa tagaatacgc
     3781 catattaaaa ttcctccact gcacatgttt ttgcgtagct ttatttatta aagtataaac
     3841 acactagact tatttttaat aagtcgttaa tacgtgtgct ctgcgaggct taaacctgtt
     3901 tttgctaacg caaaaaatga gtggcaaaat gctagccact catagttcta aaccaaaata
     3961 taatataact attcaaactg cttttcagaa cgtttaaata caataatcgt caaaagacaa
     4021 cataaaataa taaggatagc catggctaca agaatattac tatacactcc agaagaataa
     4081 tttataaatt ccagaactag tttacgatta atcaattgta gtgacaataa acctcctaca
     4141 attgctatac ctgttccctc tgataaaaaa cttgtgaaat ttagcaaact cattccagaa
     4201 gcaacttctt cttcagaaag actacttgat actatttttg atataactgt tttagtaaaa
     4261 gataatccgc ccataacaaa tataaacata aaagtagtca accacatact aaactcaaca
     4321 aaaaatgcaa tagttaaaaa acttatagag atagacaatg atcctaaaat aaaaacaaat
     4381 aatgatcctt ttctatccac taaaaaacca ccaaaataac caaaaacaat aacactcatg
     4441 gttccaggaa aaataacact attacctatt gtcgctacat ttacatgata aatagttttc
     4501 atcatataag gcaccattga tataaaacca gctactatag aaaatattag cccaccagaa
     4561 aacaaaccaa gcataaacgg aatgtttttc cctagtttag gattaataaa agggttagaa
     4621 actcttgaaa tatgtttaat aaaaatcaca aaaaagattg tgaagagtat taaaaaagtc
     4681 caattataat ttgtcgtaaa taacataaaa catataatac ttatagacat taaaacaata
     4741 cctacgatat ctaatgtatt ttttgttgat ttaccaggta ccattacttt aataagaaaa
     4801 ggtatagtta ctattgtaat cataggaagt ataagtaggt aagaccaatg aatataatgt
     4861 gctattattc cccctattga aggacctaac ccttcaccta aagctacaat tgatcctata
     4921 aaaccaaagg ctttgccttg tttttttctt gtaatatttc tagctacaac caccataatc
     4981 agtgaaggga atgcagcaga tcctactcct tgtactaacc taccaaaaat caaaataaaa
     5041 aagtgattgt gaccaataaa agcaatcaat gaaccaagac agctcaaact aataccaata
     5101 attaacaatt tttttatatt tatataatca gataattttc catatactgc tgttcctatc
     5161 gaaaaagtta acatatatgc agtgtttacc cagtttgtaa ttccaggagt agtattaaaa
     5221 tgatttgcaa tatcaggtaa agaaacattt aaaaccattt catttaatac actaaaaaat
     5281 gaaagaatac aaagccaaaa taaaacgcta taaaacaaac ctttaaattt tttatataaa
     5341 ctaaacaatt ttacctcttt acttgaggtg actaaagttt ataggggtaa attattcttt
     5401 cacctcatat aaattcccca aatttttaaa tagacacttc ataaaaaaat cctcctaaat
     5461 tagaatagtt taaatatatc atttttgttc agtaatatta aggttctgtt gcaaagttaa
     5521 attaatatac aaagttatgc aaaagcagta aattatatac tattatatca acagattatt
     5581 cggttggatt ttattatttt tcatttcttt gtatctatat tatatgattt tcaagtttgc
     5641 aacagaacct aaaatgactt atcggaagtg aatatgctta tgtatttaca aatgatataa
     5701 taatagagtc gcctatctct caggcgtcaa tttgacgtag agaggaggtg catacgcgat
     5761 gtctgaaatc tttgtgaaca tcatgaccac agcagcaagt ggttgtctcg ttgcgctatt
     5821 tgcgcattgg ctacgcaagc gtaatgacga ataggcgact agtcacacca aaaaatcccc
     5881 ttactacggc catagtaagg ggatttggtg catacatgcc tgataatctt tgttaattac
     5941 attgtaacac tataattggt aggaatgcaa agttcataaa gtttgagcgt aaatattata
     6001 attacggagt tattttattt atatctgtag tatatataaa taggaatagg gttaatgata
     6061 tttataaaac atgcattttt aattgatgtt ttaataacta tactgatata tgttatatat
     6121 tataagaatc atttgataat aatgtgagtc agtaacattt ttatatggct tagagaggaa
     6181 gttttagaat gaagaagatg ttacgtatat cgattttcat aatagtggtc tccatattta
     6241 ttgtttttaa atactcttat caaattgagg gaattctaga agaatatcca aatattttaa
     6301 aagcatttgt agcattattc actctcctta caactgttat cagtcttgtt atcgcatata
     6361 aatcatatga taatagcgtt aagcaacaag aaaaagataa agaagaaaaa aacaaacagt
     6421 tcgaagaaaa tagcgatagg attattaata gtttgaaatc tgatttagca aaatatacta
     6481 ggaaaataaa tgtttttaga ttaggatata cgaattcaga tgttgaattc tctgaacttg
     6541 caaaagaact ttctataaaa agtaatttag aggaaataga aaaacttaca tcacaagtga
     6601 gaagtagcaa aagtactgaa cttgctaaaa tggatgaagt taatatagtc aatttacata
     6661 ctgcaagtga ttcagctcta tttttatttg atatttatga aaatacatca agggaaaatg
     6721 atgggttctg ttgcaaactt gaaaatcata taatatagat acaaagaaat gaaaaataat
     6781 aaaatccaac cgaataatct gttgatataa tagtatataa tttactgctt ttgcataact
     6841 ttgtatatta atttaacttt gcaacagaac ctcattttat attatatctt tgcttacttt
     6901 tataaagaaa ctcgtttcta aattcaataa aaaattgctt tatgattaaa tttcaaatat
     6961 cgtttgaaaa atttaaataa aaatacactg acttttttca ataaaggaat tgataacaaa
     7021 ccaataacaa cgaaaataac agtcataact agttgaatta cattaaactc ttgtacaccc
     7081 gttaaaacaa agattgctaa aatcaaagga ctaaataaca tagctaaaga aatgaataaa
     7141 gataataaca aaaagccacc aaaaaatata actattaaag aaaataaaaa cacattaaat
     7201 aatatcgctc caaataaagc aaaaggattt acatttttca tacttttagc ctccttattt
     7261 tctaatgctg tatttactac taattcatct aaagaaatat cataaagatc gcttaattct
     7321 tgaattacat aaatattagg caacgtttta ccttgctccc atcgagaaac agtttgtcta
     7381 gtaacgtata attttttagc tacctcagat tgcgttaatt cctttgctaa tctcgcagat
     7441 tttaatttat tcgatatcat aagcttctcc ttgtttttta taaatttata atctcacaac
     7501 aaatccaaat taaaagaaac aaacctgtta catcccaacg aaatcaatga tgtaacaggt
     7561 ttaaaacatt aatactttat cacaattgct ccctaaaatt gtcgaatggt cggcttaata
     7621 gctcacgcta taccgacatt cgtctataag tttagttaag agttcttctc aacgaacaat
     7681 aaattttttc gtcataaatg ctacgttata attaaaatat cttttcttga ttttttggta
     7741 ttattttcac ttttatcatc caaaaagtga gtaagagcta ctgaaatttt aagttagctc
     7801 ttaaaacgca aatgagaatc aaataaatat aaatgtattt cacaaacaaa aatttgagta
     7861 atcattcgat gaatcttatt atatattttt ccgttttttt aattttctat ttaataaaaa
     7921 gataaagtga tctttatttc gggtcacttt ttaataaaat cgagcataga aaagtataga
     7981 aattgtttta ttctttccct tcttttttga acttaaaaat aaataataag atcattattg
     8041 aatacgatat tgagcaaaaa gtatttagtc aatttcaaaa agtaaaacaa atgaatgaat
     8101 tacttagatt acttttgagt gattttattt ttgatattaa tactaaaagt aataggatta
     8161 ataggatttg gataaaaaaa tcaatcctat ttataggatt gacgacgact gaagcctatg
     8221 aaatcaataa aaacaatagt attcagacaa tttaaagtgg tcttgtaaca attgtaaata
     8281 gtatgcaata ttaaggttta taatgtcgat taatttttat ttaatattaa ctataaatgt
     8341 tgttatatca acacttgtag tgaatttcaa agagcaagta agcaaagcga acggtaagac
     8401 aatccttcag ctatgctgaa taccaccaaa ggtggtactg gatttcctta tgctcatgtc
     8461 aaatactatt tgaaaatcct attatatttg taatatttcc aaaaacaaaa cgtgctttaa
     8521 gacaaaagtg gctattctct tgttcacttt ttactttaag tgcttatttt tattttcaaa
     8581 ataagcattg ttagtaaaat aattggagat aaaaaaaaag aaaactaagt aaatatcttt
     8641 actcagtttg ggatagaaaa aatcaaattt aaaattacat tcgacttatg tcttgaacat
     8701 taacgactta ctttttgttt atgatgtata tcaattgaat ctgaattttg attttttgga
     8761 atgataaaat caatcttttc tttccgatca ttaacaaagt aaatgacaaa aacgatttta
     8821 ttaagttact tttataacta agaaagattg ctaaagaata taaaaacggt tagtattttt
     8881 ataattttta aagttaaaac aacgttaaat gatcatttta tttttcatct tatgcgacat
     8941 gtttgagcca ttttcaaatg aataataacc atttatagaa aaaataggac taaaacagaa
     9001 acgttttagt cctacctact tgtttaacta cagttcattt tcagatttac tcaattgcca
     9061 ttgaagataa agttcgactg cagttaaaag aacattaatc attgccaaag taactttaat
     9121 ctttttctta gtactcataa gtcttcctcc tttctttaat agcagcatgc tatattgtga
     9181 tattgtgttg atcttatttt gttatcccct cccttacctt tcgtttgatc taggtggttg
     9241 ccttagcaac cacttgtaaa taaaaaaaga gaacatctat ttaaagatgc tctctaattg
     9301 aatcattatt gattaaataa agaagtgatt ggtaaatgat cacgtcgttt attaagcgta
     9361 tgcatttcag cgaattcaga cttaagggat ttcattaagt acccttgcat ggcttcaacg
     9421 gtttcatttt tttgaataag catagctttg aaacgtttaa gaacatgaag tatttctatt
     9481 tccatatctt ctaataagta atatgtatca atagaattat taaaggacgt cttggctttt
     9541 aataatacag gtttgatgat tttaatttca tttacagaaa agttacttaa atacctttga
     9601 atactttgag gtagttcttc gagtaattgg aattttaaag cttcattatt aaagtttgaa
     9661 ttgttgtgat ttgaatgatt tgtatgatta ctaggaaaag ttagcttatt atcattcaaa
     9721 tcattcgtat cattactctc agttttaata taatcagtat cattattctc agtatcatta
     9781 gactgtgaat ttggaagttc ttgaccactt aaattcacag ttctagaact tccaaattca
     9841 ttgttctgga actgtgaatt tggaagttcc ttgctatgac tggctttaat gtcataatta
     9901 ggttttaata aatataatct atttggttta ttaaggccaa cacgttcttg agttaataaa
     9961 ttaaaactta ttaactcttt ttttaatttt ataatttttt gttctgcata acctaagtat
    10021 tcgcacaaat gtttattact gaaaataaag taaatgttat tatttttatc tacccattca
    10081 ttttggatgg ataattcaaa gcgatctttt aataacgcat acataatttt ggcttccgcc
    10141 gacatttttt taaaatatgc atcttcgaat aaatatttag gtagttgata aaacctttca
    10201 gtttttactt gtgataaatt gtatttttca aaattgggca taataaaaac ctcatttcca
    10261 tttttaggat tgaggtaata aaacaatttt tacgtaagtt atatgttttg tgcttgcact
    10321 tagatgatta gatagatata atacaagtat caaaaaatat ataaacaaac gagtgcgaat
    10381 cgttttatta ccgagagtca atgctacgcc aatagcattg actcttttag tatttataaa
    10441 gcaatattaa cacttttaag aaagtatata aagagtttta aatgtagtta aaagcacatt
    10501 gccatggcaa aatgtgtagt tcattgtttt agtacctaat taagctccaa aaacatatta
    10561 taggtagcta attaggtgca tatgtagtaa ataggtagta aatttagtgg taattgatga
    10621 aataaaattc attaggtggt aaaatttagg tactaaatta ggtacctaag ggtggatgtt
    10681 atgagaacta ttaaaatggt tgctgatgaa ttaggtgtaa ctaaacaaac tattgttaat
    10741 aatgctaaaa gtttaaatat aacttttgaa aaagaaaatg ggattaatta tattgatgat
    10801 aatgattatt tgaaaattat agaaaaaatt actaagaaag agagtacaat ccaaaataaa
    10861 gaatcagtaa aaaaagaatt gtttggtgaa aatactgcaa aatcagaaaa gaatatatat
    10921 aataattcaa atagttctga gacattaaaa acaaaagtaa acgaattaga aaagcaaata
    10981 gaaatctttg aaactagagc taaaaatgat gaaaaatata ttgagaattt aactaagcaa
    11041 ttagatcaac aaaatagcaa tgttaatacg ttaaataaat tgttggagaa tcaacaaata
    11101 ttagctttag aaagcaataa aaaaattcaa aaactagaaa gtcaattaga agaagaaaga
    11161 cagcttaatt attcttttga tacagcgacg aataatagac aaaatattaa tccgcaagaa
    11221 gcaactttta ctgaagaatc gcaaaatatc aaccaacaac aaacaaagcg tcaaccaaca
    11281 gaagtaaatt acaaggatat agccgaagag aaaaagaatg acagtacaga tgaaggtgaa
    11341 ttaacaaaag aggataagtt cgttgaagaa acgaagagtg atcctgatga taatagggag
    11401 gtagaaccat ctaaaaaggg attttggagt cgattcttcg gtaattaaaa atgaatgtaa
    11461 aaggtgtatc aagggggtat aaatctttga tacacctttt atagtgatga aacttctgat
    11521 aatcatcgat tatgttaact aattatttaa agaggagcaa tctttaaata tatatgtaaa
    11581 gcacagccta atgcaataac ttatctaaac taaaagttaa gttattgcaa ctaaaagcag
    11641 acgaaagaat aaaaagattg gatgatgaaa aatatgtttg ccatttttgt agcattaatt
    11701 agtttaacgt cagtgtgggt gggttataaa atagacaatt caatgaaaag aaaatctgaa
    11761 attgaagatt caaggataaa ttggattcag aaagtaagag aagtaaatac taatttgata
    11821 aaagcatttt atgatttcaa cactcatcaa aatttttata gtgaaaaaac taaagatatt
    11881 aatatgttag ataatatgag aagcaccttg ttagaaggtt tagaatatga atcaaggaaa
    11941 agagacaata atgcggaaaa atacaaagaa gaaatagaca atatacaaga aaaggtaaag
    12001 gaacaaacga aggttttaaa taacaaaaaa atagatagaa ccagtgctat gtataatcta
    12061 tttacttcta tagaagtaat gaaaaattta tttccgataa ataaatatga tattcataaa
    12121 gtacgaatcg aacataaaaa aaatactagt tgcagttgaa agtagtgcaa gtttttataa
    12181 aggggattta tcaattagca atgagaaaat ctatgattct ttaaatgaat taaaaaaaaa
    12241 tatcagagaa tcttatgatg gtaataatac tttagaagaa acaaaaatag atgaatataa
    12301 agattttatt aataattacc tgaaaattga atgggaaaaa gttaaatcaa gaaaaacata
    12361 atccctccat attaaaaatg ttcgttattt agatatattt taaatttgaa acgcttaaga
    12421 cacttctttt aaaaggaagt gtcttttcat gtattagcat attattttct gcaatcccac
    12481 ttacttattt tgagccatct gtaagatcat ataatgatgg ggtttcgtta gctatagtga
    12541 cagttactac agttggctat ggtgatatca gtccagagac actaattggc agaataacaa
    12601 gtgtttatct gatgtttttt tggtatcggt ttagttggaa tgataacagg ttcaatagca
    12661 acttattttc tgaaaaataa tgagaagtct aatataaaag agtcgcttaa acatgacata
    12721 gacaatatag aaaacctctc aaataatgat atagaaagat taattaaaat aatcaaaacg
    12781 tatcgtgact aaaattttaa tgagaaaaaa tatatatgaa gcaaaataat ttttaggtca
    12841 gcctaattta tactataata ttcattgata aatttaatat tcaatgagga gatttttata
    12901 gtgaagaaaa gtttagaaga aataaatgga aaagtttctt ttgatagcga agcaaatggt
    12961 atcaagaaac taataatgta tctaggtcct ggacttcttg ttgctgtagg ctatatggat
    13021 ccaggtaatt ggattacttc aatggcagga ggagcacaat ttggatatac attattattt
    13081 ataatattat tatcgagctt atcagccatg ttacttcaaa gtatgtgcgc tcgtttaggt
    13141 attgcgagtg gtatggactt agctcaagta actaaacaca taagtaataa gccgttatcg
    13201 atagcagcct ggattgttac agaattagca attatggcta cggatattgc agaggtcatt
    13261 ggtagtgcga tagcactaaa tctacttttt gatatacctt tagtagtggg agtaactatt
    13321 actgtattag atgttttact tttactatta attattaaat ttggctttag aaagattgaa
    13381 gctatcgtag gtgtattaat ttttacagtt ctttttatct ttgtatttga agtttacttt
    13441 gcttctccag aatggagtgc tgttttaggt ggctttattc caagtacaga aatagctact
    13501 aacaagggtg tgttatacat ggctttaggt atcattggtg cgacaatcat gcctcataat
    13561 ttgtatttgc attcttcaat tgttcaatca cgtaactata tacgtgaaag taaagctaag
    13621 aaaaaagagg ctattaaata cgctattatt gattcacata tacaactttc aattgcgttt
    13681 attattaatt gtttgatttt aatattaggt gccgctctat tctttggtaa tggtgaagac
    13741 ttaggacgat tttatgattt atataatgct ttacaagaat ccgagtttgc aggagctata
    13801 ggtggtgctg ttatgagtac attatttgcc atagctttgt tagcttcagg acaaaattca
    13861 accattactg gcacattatc aggacaaatt gtcatggaag ggtttttgaa tataaaaata
    13921 cctcaatggg caagaagatt agttactaga ttaatcgctg tgattcctgt attcatatgt
    13981 ttatggttat atggttcaag tacttctaag attgaagatc ttttaatctt cacacaagta
    14041 tttttaagtc ttgcattacc ctttagtatt attcctttaa cgttagcaac caataatcct
    14101 aagataatgg gaaaagaatt tacaaataaa acatggatta atattattgc ttgggtttta
    14161 acaatcatat taagtatatt gaatatatat ctaattatag aaacatttaa tgagttttta
    14221 taatttaatt gatttaaaaa cacatcttct tagtaaaata agaaggtgtg ttttttgtct
    14281 atttggagcc taccttaatt gaaccattat tgatgctagt aaaacagtat ttctgtatgt
    14341 atgattaggt tgtcaaaatt attcgttatt gagaaaaaat atagaaaaaa agagggcaaa
    14401 aacgctctct ctttttcctg tcttattatt aaaatctcat aatacatgat taacatatat
    14461 tttgggacgc tgtgagaaac gctcatttgc attgacaatc aatttatcaa gataatcccc
    14521 ttatcatgtt taattctata aactgtttgt cttgtaatat taacttcttt ggcaatttta
    14581 ctaattgctt gcccttcttc taacatttcc accacgcgat gataaataac acgtttctgt
    14641 gggtctttag catttggtga ataaagtaag gggcgccctt tatatacgcc tttttccttc
    14701 gcaacttgaa ttccttgcgc ttgtcgacgt ttactttcat ttctctcttg ttctgaaacc
    14761 attgctaata tttgaatgat taaatctttc ataaacttat ccagtaatgg attgccaatc
    14821 acttcattca tcataggtaa gctggtaatc attaactgaa cgtttttttc ttttaaataa
    14881 ttcacagttt caataatttc atcatagtta cgtcctaaac gatcaataga ttccacaacg
    14941 aatcgatctc ccattctgac aaaattgagt gcttcttgaa atacaggtct attttccact
    15001 gactttcccg actgtttctc tgtaaagatt ttctccacac caaacgtctt taaattatcc
    15061 aattgtcttt ctaaattttg atctatcgat gatactctcg cataacctat aatcattcat
    15121 cttcactcca tgattaatat acaccctaat catacgtttt aattgcgata atttcaacaa
    15181 cttattttgt atgattaggg tgtaccacaa gtagacatat agacaaatat ttttactttt
    15241 tagcgctttt aacattatca aaaggattat ttaacttatg tttaatacta actatttata
    15301 cttattaaaa tagagttaaa ttttattgaa aggactcatt atgatggcta taaaatttat
    15361 aagacaatac gatgaaaagg attgtggtcc tacttgcctt gccatgattt cacagtttta
    15421 tggtaagcgt gtatctatcc cacgtttgcg cgaatatgct aaaacagata aattaggtac
    15481 aaatttatat ggtctcgtac aagcaggtaa aaagattggt attgagttaa ctggcgtaaa
    15541 agctgattcc tttgatgatt taaaacaagc acaattacca gttatggtac atattattaa
    15601 tcaacaaggt tatgatcact atatcattat tgaaaaaata aaaaataaca cgctttatat
    15661 tgtcgatcct gctaaaggta aatataagtt atcaagtact gaatttggaa aatattggac
    15721 taatattgct gtattaattg ataaaacaga tgattttact actgacaatg aatcaccctc
    15781 gtatcttaat atttttattg atatatttaa aaataattat ggaaagttgt tatttattgc
    15841 ttttatctca ctatttatta atattgttgg tattgtcggg gctctatatt ttaaattatt
    15901 aaccgatcat attattccat ccaatgttct taaaaattta catattatta gcttcggtat
    15961 tttactttta tacataatca atgcactcat taattattta aggtttcaac ttatcttaca
    16021 tttaagtttg aaaatcgatg ttaatttaat gaaagattat ttttatcatg ttttacatct
    16081 tccgatgaac ttttttgata cacgtaaatc tggcgaaatc ctacaacgtt tcatggatac
    16141 atctaaaatt cgtgaagctt tatcatcttc aacggtaacg ttgctagttg atactttcat
    16201 gattattatc ggtgctatat tactttatat gcaaagtcct ttgttactac tgataacaat
    16261 tatttttata ccttgtttta ttatttgtag ttacacttta cgtaaacctt ttgaaaaata
    16321 taatcaaaag gtggctgaaa aagatgctga attgagttca tatttaatag aatcctttga
    16381 tggtagtaat actattaaaa gttatcaatc tgaagacgat cgtttctaca ttggtactac
    16441 taaatttaat ggtattattg aaaacttatt aaaactgggt agattttcta atatacaatt
    16501 aacggttaac aactttttaa aattaactat cagtcttgtt atattgtggc ttggtagtta
    16561 cttagtcatg acggatagta tgacgttagg tagtttatta gcttttaatg ccttaactat
    16621 ttattacctt gatcctattg aacgtctcat aaatattcaa ccaacactgc aatcttcatt
    16681 tgttgcagca cgtcgtattg ctgaaataac tgatttagag accgaaactg aattatatac
    16741 ttctaaacaa ccttatactt ttaaaaacaa cattcgcatt gaaaatgtaa actttcagta
    16801 tggctttcga agtgtggtat tgaaggatat taatttaaat attaaaaaag ggcaaaaggt
    16861 tgctattgtt ggtgaaagtg gtagtggtaa atcaactata ggtaagttac tcaatcgcta
    16921 ttacactgct tcagaaggta atattatgat tgataactat attattgatg atattgatct
    16981 ttctgactta cgtaagaata taggctatgt ttcacaaaac acattccttt ttgctgatac
    17041 aattaaaaac aatcttttac atggtagcaa taaatacaaa agtgatgaag atatcgttaa
    17101 agcttgtcaa ttagcagaat ccttagattt tatacagaaa ttcccagatc agtttaacac
    17161 tatgttagaa aaagaaggag ctaatctatc gggcggacaa ggccaacgct tatctttagc
    17221 acgtacattt ttaaaagatc ctgatatata tattttcgat gaagctacaa gtgccttaga
    17281 tagtttaact gaaaacaaaa ttatggagca tattgactta ctaactcaac atggtaaaac
    17341 cgtaattatt atttcacata aattaagtac tataaaaaat gctgataata tctatgtttt
    17401 aaacgagggt caaattgctg agaatggtac acatgatgag ttgattcatt taaacggtat
    17461 atataaaaat ttatggcaac ttcaaatgaa aatagactga ttttatatta atatactcta
    17521 tttattaaat atatttcgat aataaaaaaa ataaactcaa aaaaaagctc acttaactgt
    17581 ctatttacat tctctttata ttcaaatgct aatttataag atgtaagatg aaattactta
    17641 aaggaggact atttcaatgg aaacacta
//
