LOCUS       NZ_CP098728.1          15044 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP098728.1 Staphylococcus aureus strain SauR3 plasmid pSauR3-1,
            complete sequence.
ACCESSION   NZ_CP098728
VERSION     NZ_CP098728.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-06-07 22:03:28
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 6421
            Orig. end    :: 21465
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15044
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[5000:10044]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..10044
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..15044
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15044
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             complement(713..1456)
                     /locus_tag="ctg1_11"
                     /transl_table=11
                     /translation="MKNKLLFKIFLSLSLALSVYSINDKIIEVSNTSLAADVKNFTDLD
                     EATKWGNKLIKQAKYSSDDKIALYEYTKDSSKINGPLRLAGGDINKLDSTTQDKVRRLD
                     SSISKSTTPESVYVYRLLNLDYLTSIVGFTNEDLYKLQQTNNGQYDENLVRKLNNVMNS
                     RIYREDGYSSTQLVSGAAVGGRPIELRLELPKGTKAAYLNSKDLTAYYGQQEVLLPRGT
                     EYAVGSVELSNDKKKIIITAIVFKK"
     CDS             1572..1955
                     /locus_tag="ctg1_12"
                     /transl_table=11
                     /translation="MKFKKLIVLATIGLFFSSFNISYAEDLGTRKLVGTTKDPKSKYTA
                     RYDPDYSVYCSATMITDKIGLTAKHCAGNRKINGCIGAVYPVHSGLSTPFGKMNICEYI
                     PNDSNDIAIIKGEEKDMDNTVLL"
     CDS             2215..2889
                     /locus_tag="ctg1_13"
                     /transl_table=11
                     /translation="MNYFRYKQFDKDVITVAVGYYLRYALSYRDISEILRERGIYVHHS
                     TIYRWVQEYAPILYQIWKKKNKQAYYKWHIDETYIKIKGQWHYLYRAIDADGHTLDISL
                     RKKRDNHSAYTFIKRLIKQFGKPQMIITDQAPSTKVAMSKVIKDFKLTPNCHCTSKYLN
                     NLIEQDHRHIKVRKISYQSINTAKNTIKGIECIYGLYKKNRRSLQIYGFSPCRVISIML
                     AS"
     CDS             3071..3361
                     /locus_tag="ctg1_14"
                     /transl_table=11
                     /translation="MFKSNKLDSEAQIKPISRVQAYRILNHSAKSIGLSEIGTHSMRKT
                     FGYHYYKKTKDVALLMDLFNHSSQVVTLRYVGISQEVINSSISETMQNVYY"
     CDS             3482..3853
                     /locus_tag="ctg1_15"
                     /transl_table=11
                     /translation="MGIIKGNIETGGIKELHAKRLVSLLKSNKKYYLYIGFQECPYCRD
                     FSETLREFSSNANLPIYYFNLNSGNSKLNESDKKFIEKVLNESVNLRGTPTFLKIEKKK
                     IIAKFEGSQTTIRDLNDIN"
     CDS             3875..4042
                     /locus_tag="ctg1_16"
                     /transl_table=11
                     /translation="MYKNFDLFLGIVSLLSAIIIYIIDSDSKGIALVVLIMGIVFILTS
                     MIRKKDKFKV"
     CDS             4323..4829
                     /locus_tag="ctg1_17"
                     /transl_table=11
                     /translation="MNSIEQKILNFILECKSTSDEREKIEITEILSRCLLHTYVFIALS
                     MIISVIVDRIYFINSIGTIFLILIFLYISGFISIELRRKSLANINIYTYEEYQNKIKII
                     KFIGLFNGIYFGAGMFLFMEIVYKYIQNIDVNLNFTKIVLYILLGLPFGVFSYYIQKSK
                     LNKEY"
     CDS             5001..5207
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_18"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1.1e-17,
                     bitscore: 56.0, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLETKELVSINGGKKNTWQQNVSGAIGSTVAGAGLGGAICGPA
                     CAVVGAHYGPIIWAGVSGATGAF"
     CDS             5226..5417
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_19"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 7.9e-13,
                     bitscore: 40.4, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLKIEELKKFNGGNKWGSSAIGAMGGAATGIKLCSAGGPWAMA
                     GCGVVGGAIGGFTGYHGY"
     CDS             complement(5467..6207)
                     /locus_tag="ctg1_20"
                     /transl_table=11
                     /translation="MTHSIFICDDDISYLNKIKTIIEHYILFHEEQFHIEKITTSTIEF
                     LKYIEDIKISGGVYFLDMDFKQDINGIDLALKIKQRDIQAKIIFITNYSKYATLTLKNK
                     IEAVDYINKSQNIDTLQDEIISNLKYCYNSIIKQKNYSKSVFSFSVNSTTYFIDINDIL
                     FIESSHIPHLLTLATLDSKYNFYGKISNIDKDYENLYKISRSCLINPKNMTKIDFNKRE
                     VYLKENFVKKFSLSRSKLLKSYQP"
     CDS             complement(6227..7531)
                     /locus_tag="ctg1_21"
                     /transl_table=11
                     /translation="MIIDTKLYILRMFLSILIYTYFFYKIYFQTKSPEKLKIAFIGLLI
                     WFIFSIFLGDFIEIFFVVCIAIYYIFLHKDLNKLNVILIFFISIKFININSSYIIIYIY
                     NVTGISGDYLVYLQLLIISIQVILYIKIFKKYNFSTYIYSFVSLSLTLLLLYIYLSIFF
                     ITYIFNKIYYFERFIDLLLFFVIMQGTFIFFLIFYENRVQKEQELKRNNEIKFENINFY
                     SQLIEKKNLEIQKFNHDLNNIIISINEVEESKEVQRFKRELSYISSYIKDIPFSSNKVD
                     THYLKNIKNPYLKNLFLNKIEVMMNKGISFNFECLKMVSEIKRVHILDLVRIIGILCDN
                     AIEEAEKINGGFINIYIYQDNSLLEFFVENNFMNSNQLSIHKLVEPGFSTKEEHKGLGL
                     TIIEDIIEKNKYISVNYEINNNDNIFKAILIINIS"
     CDS             complement(7543..7668)
                     /locus_tag="ctg1_22"
                     /transl_table=11
                     /translation="MKQLDIPQLLIINGGSGGNYTLPGQPKGDIKKCILSFFKNC"
     CDS             7885..10044
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 287.5; E-value:
                     3.5e-87)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_23"
                     /sec_met_domain="Peptidase_C39 (E-value: 2.8e-41, bitscore:
                     132.2, seeds: 36, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR01193 (E-value: 2e-199, bitscore:
                     656.2, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIPFIQQEDAKDCGPVCIAMICKFYNKKVSIEKLRKISGTDNN
                     GTNLFGLIELGQYLGLELSGVQAESTKNLYEIHYPCIAHIINKKGSEHFVIIEKVLNDK
                     VYIVDPDIGRYSTSLNQFDTYWTKILLLIEKKDDFTTYDDRPSISTLFRSLITHNSKYI
                     GLIILSSLLINLFGFLGTFYFKLLIDDILPSNIVYNLHILSGSILLMYLVQSLITYFRS
                     HLILFLSLKIDIKIMLDYYNHVLKLPMGFFETRKSGEILSRFMDSNKIREAFSTVTVTF
                     FIDTLMIFLGSILLYLQSSRLFFITLIFVPIYILLALMFRKPFEKYNRQQMEQNSELNS
                     YLIETINGISTIKSYTAEEEVSIKSEKFFIRLIKKVLKLGIITNIQMSIKGFLSLLIST
                     VILWIGSYYVINNQMTLGELITFNALVVYFLGPIERMIDAQPVIQSAIVASRRIVEILD
                     LEVEDKENAVSEFSFNNQIQISNLYFNYGHREDLLKDINITIPKDTFVALVGESGSGKS
                     TLAKLLVNYYQAKQGDIQIDQKNIVSIENKSLRKNIGYVSQKNFFFSGSIIENLLLGND
                     KHITMDEIIWACKNAEIHDFIEELPQGYQTTLEADGDNFSGGQLQRLALARLYIKNPEV
                     FILDEVTSALDSTTENKIINNLHSVSKKGKTVIIISHKLSTIEKVDNIYCLKNGRIVEQ
                     GNHKQLLSNRSEYYTLWKNQTTEGI"
     CDS             10046..11041
                     /locus_tag="ctg1_24"
                     /transl_table=11
                     /translation="MKKIYSFEDFQDSTVYLNNSPSKFITRSLIILFIIFMAVIISIFF
                     IKKTDYIKSTAVITPKNNPINITTDKDIKVKKLLKDNGELVQQKEKVITIQDINNDKKQ
                     ITSKIKYKKESLKDLSLLYDKIDNYPLESDKKLHTDYSEKYFESYKKQYNQTDYLDNSQ
                     RNNIKSQSLQILIEKINTLKDELHELSVIKGNDNQDYVTKNGYIFYPKEVQEGLIIPKG
                     KLLYQIYKNRDKEVVTYISSEDILSLNPNQKVSITFKTKKDEFYLQGNIKYISKFPEES
                     KNNETFYKVKISLKDKIPKQLENVYYLKGTSYVELEKETIAQYLYRKIKE"
     CDS             complement(11118..11792)
                     /locus_tag="ctg1_25"
                     /transl_table=11
                     /translation="MNYFRYKQFDKDVITVAVGYYLRYALSYRDISEILRERGIYVHHS
                     TIYRWVQEYAPILYQIWKKKNKQAYYKWHIDETYIKIKGQWHYLYRAIDADGHTLDISL
                     RKKRDNHSAYTFIKRLIKQFGKPQMIITDQAPSTKVAMSKVIKDFKLTPNCHCTSKYLN
                     NLIEQDHRHIKVRKISYQSINTAKNTIKGIECIYGLYKKNRRSLQIYGFSPCRVISIML
                     AS"
     CDS             complement(11832..11951)
                     /locus_tag="ctg1_26"
                     /transl_table=11
                     /translation="MQYNTTRYIDENQDNKTLKDMMKNGKQRPWREKKVLLQS"
     CDS             complement(12133..12480)
                     /locus_tag="ctg1_27"
                     /transl_table=11
                     /translation="MNYENTCDVICVHEDKVNNALSFLEDDKSKKLLNILEKICDEKKL
                     KIILSLIKEDELCVCDISLILKMSVASTSHHLRLLYKNEVLDFYKDGKMAYYFIKDDEI
                     REFFSKNHEGF"
     CDS             complement(12499..13116)
                     /locus_tag="ctg1_28"
                     /transl_table=11
                     /translation="MIQTVVAAAVLYIATAVDLLVILLIFFARAKTRKEYRDIYVGQYL
                     GSIILILVSLFLAFVLNYVPEKWILGLLGLIPIYLGIKVAIYDDCEGEKRAKKELNEKG
                     LSKLVGTVAIVTIASCGADNIGLFVPYFVTLSVTNLLLTLFVFLILIFFLVFTAQKLAN
                     IPGIGEIVEKFSRWIMAIIYIALGLFIIIENDTIQTILGFIF"
     CDS             complement(14359..14529)
                     /locus_tag="ctg1_29"
                     /transl_table=11
                     /translation="MLSYGGLLKQKHKILNLDDAEDGNLINTSDEDKTTDEEKKHIQLP
                     QFGISKSKIII"
ORIGIN
        1 tttggttgcg caaaaaacga gatcatcaat cagcatatgc gtttattaag cgtcttatta
       61 aacaattcgg taaacctcaa atgataatta cagatcaagc accttcaacg aaggttgcaa
      121 tgactaaaat agcgaaagtg tttaagctga acccttactg tcattgcaca tctaaatatc
      181 tcaataacct cattgaacaa gatcatcgtc atattaaggt acgaaagaca aggtatcaaa
      241 gtctcaatac ggtaaaaaat acactcaaag gcattgaatg tatttacgga ttatataaaa
      301 agaaccatag gtctcttcag atctatggat tttcgccatg ccacgaaatc agtcatatgt
      361 tagctagtta aacgaacact gaaatgataa aaaaggaaat tagatggttt tctaactttg
      421 caacagaacc gagacggtta tttgaatgat atttaagaat cattacccta caaaaagcgt
      481 agaggtttaa ttcgtggttt ttgtagggtg tagtaagaga atataagtga gtgcggtggg
      541 aatgaataat ttgagaatat caaagttgat tatcaaaata tcataaaacg ttctgaaaga
      601 aataagttta aagcgtattt ttaggattat taatcatgat tcttttagtt atagaaaata
      661 ttaattaaac atttttaatt tattaatcct tgttattact ttgtttatat ttctattttt
      721 taaaaacaat agctgttatt atgattttct ttttatcatt tgacaattct acacttccaa
      781 cagcgtattc tgtgcctcta ggtaataaaa cttcttgttg accatagtaa gcagttaaat
      841 ctttagaatt aagatacgca gctttagtcc cttttggtaa ttctaacctt aattcaatag
      901 gtctaccacc tacagctgct ccactaacta attgtgtact agagtatccg tcttctctat
      961 atattctgct attcataacg ttattaagct ttctaactag attttcatca tactggccat
     1021 tattggtctg ttgtaattta tataaatctt catttgtaaa tccaacgata cttgtcaaat
     1081 aatctaaatt taaaagtcta taaacgtata cagattcagg agtagtagat ttagaaatag
     1141 atgaatctaa tcttcttact ttgtcttgag ttgttgaatc tagcttatta atatctccac
     1201 ctgcgagtct taatggacca tttatcttag aactatcttt tgtatattcg tatagagcta
     1261 ttttatcatc cgaactatac ttagcttgtt ttataagttt attcccccat ttagttgcct
     1321 catctaaatc agtgaaattt ttaacatcag ctgctaaaga agtattagat acttctatga
     1381 ttttatcatt aattgaataa acgcttaatg ctaaagataa actcaaaaaa attttaaaaa
     1441 gtaatttgtt tttcataaaa atctcctctt gattgttatt tatatataat ttcattatat
     1501 gatattttat tattaaaaga aaatatttat tctgtttttg tatacaaaaa atatgaatga
     1561 ggagtgatat tatgaagttt aaaaaattga ttgttcttgc tactataggt ttgttttttt
     1621 cgtcatttaa catatcatat gcagaagatt taggaactag aaagttggta ggtacaacca
     1681 aagatcctaa aagtaaatat acggcaaggt atgatccaga ctattcagta tattgttctg
     1741 caactatgat tacagacaaa ataggattaa cagcaaaaca ctgtgctggt aatagaaaaa
     1801 taaatggatg tataggtgcg gtgtatcctg ttcattcagg gttaagcaca ccatttggta
     1861 agatgaatat ttgtgagtat atacctaatg attcgaatga tatcgctatt ataaaaggcg
     1921 aggaaaaaga tatggataat acggttctgt tgtaaagttg aatttctatg cagatctata
     1981 caaagccaat aaatataaat ttaatttaac agcatttctc tagataaaaa agcgataata
     2041 tgcaatttat acacctcctc tctacgtcta gattgacgcc tgagagatag gcgactctat
     2101 tattatacta tctgtgaata tacaagcata tctacttccg ataagtcatc ttatatggtt
     2161 ctgttgcaaa gttagaaata tagtataata gtcaacaaaa atgaggtgca gaggatgaat
     2221 tatttcagat ataagcaatt tgacaaagat gtcattactg tagccgttgg ctactatcta
     2281 agatatgcat taagttatcg tgatatatct gaaatattga gagaacgagg catctatgtt
     2341 catcattcaa caatttatcg atgggtacag gaatatgctc ctattttgta tcaaatttgg
     2401 aagaaaaaga ataagcaagc ttattataaa tggcatatag acgagacgta tatcaaaatt
     2461 aaagggcaat ggcattattt atatcgcgct attgatgcag atggccatac actagatatt
     2521 tcgttacgta agaaacgaga taatcactca gcatatacgt ttattaaacg tcttattaaa
     2581 caatttggca aacctcaaat gataattaca gaccaagccc cttcaacgaa ggtggcaatg
     2641 tccaaagtga ttaaagattt taaacttacc cccaactgtc attgtacctc taaatattta
     2701 aataatctca ttgaacaaga tcatcgtcat atcaaagtaa ggaaaataag ttatcaaagt
     2761 atcaatacgg caaagaatac gatcaaaggc attgaatgta tttatggact atataaaaag
     2821 aaccgcagat ctcttcagat ctacgggttt tcgccatgcc gtgtaattag catcatgcta
     2881 gctagttaat acgaagtatt attttaaaca taaggttaga cacttatttt ttaactttgc
     2941 aacagaacct attaaggact atacaattaa actcagagaa cagaaaaccc gtaaacaaaa
     3001 acaaatcccc ctttatcatc taaagaagga tattgatcgt tatattcagt tcctggagga
     3061 tgaagattat ttgtttaaaa gcaataaact cgattctgag gcccaaatta aacctatcag
     3121 tcgtgtacag gcttatcgaa ttcttaatca ttcagcaaaa tcaatcggtt taagtgaaat
     3181 tggtacacac tcgatgcgta aaacctttgg ttaccattac tacaagaaaa caaaggatgt
     3241 ggctttgttg atggatttat ttaatcattc ttctcaggtt gttacattga ggtatgttgg
     3301 aatcagtcaa gaagttataa attcttcaat aagtgaaaca atgcaaaatg tctattatta
     3361 attgtaaaga tatctcatta tgtctttgct aaagtttaaa taaatataat tttacatagt
     3421 gatactctac tcaagactat atattaggat gtcaggatat ttttaattcc tctaatcttt
     3481 attgggtata attaaaggaa atatagagac tgggggaata aaagagttac acgctaaaag
     3541 gttggttagt ttgttgaaat ctaataaaaa atattatctt tatataggat ttcaagaatg
     3601 tccgtattgc cgagattttt ctgaaacatt aagagaattt agtagtaatg ccaatctccc
     3661 tatttattat tttaatttaa acagtggaaa ctctaaacta aatgaatcag ataaaaaatt
     3721 catagaaaag gtattgaacg aaagtgtaaa tttaagagga actcctacat ttttaaagat
     3781 tgaaaagaaa aaaataattg ctaaatttga aggttctcag acaacaatta gagatttaaa
     3841 tgatattaat taaagtatat aaggtgtgaa aactatgtat aaaaattttg acttattttt
     3901 aggtattgta tcattactat ctgcaataat catttatatt attgattcag atagtaaagg
     3961 gatagctctc gtagttttaa taatggggat agtatttatt ttgactagta tgatacgaaa
     4021 aaaagacaag ttcaaagtat aatttacttt gaacttgtct tttttgtcaa atatatatga
     4081 caaaaaaggg atgaatatgt acaatatatg cgacattgag gtgaagataa ttgaataaaa
     4141 taaaagaatt taggaaaaaa aggggttatc acaattagat ttagctagaa atattttagt
     4201 ctctagacaa actataaatt tgattgaaaa taacaaatat aacccatcgt tagatttatg
     4261 tttaaaatta gcaagtgtgt tagaaacaga tttaaattca ttgttttggg aggaaaaaga
     4321 ccatgaatag tattgagcaa aagatattga attttatttt agagtgtaaa agtacatctg
     4381 atgaacgcga gaagatagaa atcactgaaa ttttaagtag atgtttactt catacatatg
     4441 tgtttatagc tctcagtatg attatatctg taattgtaga tcgcatatat tttatcaatt
     4501 caataggaac tatattttta attttaattt tcctatacat ctcaggcttt atttctattg
     4561 aattgagaag aaaatcttta gctaatatta acatttatac gtacgaagaa tatcagaata
     4621 aaataaagat tataaaattt attggtttat ttaatgggat atactttggt gcaggtatgt
     4681 ttttatttat ggaaatcgta tataaatata ttcaaaatat agatgtaaat ttaaacttca
     4741 caaaaatagt attatatata ttattaggac tgccttttgg tgtatttagt tattatattc
     4801 agaagagtaa attaaataaa gaatattaag aggacaatat aggatacttt tcattatttt
     4861 taagaaaagt atcctatatt gtccttcttt ttctatatac ttattcaaga taaaattctc
     4921 atgattaagt atatttttac atatctttaa tttttatatt ttaaaattaa tatgtactaa
     4981 aaattaggag gcgtaataaa atgaaaaaat tagaaacaaa agaattagtt tcaattaatg
     5041 gtggtaaaaa aaacacttgg caacaaaatg ttagtggagc tataggttct acagtagctg
     5101 gagcaggttt aggaggagct atttgtggtc cggcttgtgc agtagtaggt gctcattatg
     5161 gaccaattat atgggcagga gtatctggtg ctaccggagc attttagagg aggtattgta
     5221 tagatatgaa aaaattaaaa attgaggaat taaaaaaatt taatggtggt aataagtggg
     5281 ggagttcagc tataggtgca atgggaggag ctgctactgg aataaagctt tgttcagctg
     5341 gtggtccttg ggcaatggct ggatgcggcg ttgtaggtgg tgctataggt ggatttacag
     5401 gctatcatgg atactaaaat aaaaaacgaa atctatttca atagatttcg tttttagtat
     5461 ataattttag ggctggtatg actttaaaag tttggatctg gatagagaaa attttttaac
     5521 aaaattttct ttcagatata cttctctttt gttgaagtca attttcgtca tattcttagg
     5581 attaatcaaa catgatctag aaattttata tagattttcg taatctttat ctatgttaga
     5641 aattttacca taaaaattat atttagagtc taacgtcgct agagttaata aatgaggtat
     5701 atgagaactt tctataaaaa gtatatcatt tatatcaata aagtaagtag ttgaatttac
     5761 tgaaaagcta aacacagatt tagagtaatt tttttgttta attatagaat tataacaata
     5821 ttttagatta cttataatct catcttgcaa tgtatctata ttttgagatt tatttatata
     5881 atcaacagct tctattttat tttttaaagt taaagttgca tacttactat aatttgtaat
     5941 gaatattatt ttagcttgaa tatctctttg ttttatcttt aatgctaaat caataccatt
     6001 aatatcttgt ttaaaatcca tatctaaaaa ataaacaccc ccacttattt taatatcttc
     6061 tatatatttc aaaaactcta ttgttgatgt agttattttt tcaatatgaa attgttcttc
     6121 atgaaataat atataatgtt ctattatcgt tttgatttta ttgagataac taatatcatc
     6181 gtcacaaata aaaatagaat gcgtcatatg tgctcctttc ctgttattac gatatattga
     6241 ttattaatat agctttaaaa atattatcgt tattattaat ttcataatta acactaatat
     6301 atttgttttt ttcaattata tcttcaatta tcgtcaaacc taatccttta tgttcttctt
     6361 ttgtagaaaa tccaggttct actagtttat ggatagataa ttgattgcta ttcataaaat
     6421 tattttctac aaaaaattct aataaactat tatcttgata tatatatata tttataaatc
     6481 caccattaat tttctcagct tcttcaatgg cattatcgca aagaatccct ataattcgaa
     6541 ctaagtctaa aatatgcact ctttttattt ctgataccat ttttaaacat tcaaaattaa
     6601 atgatatacc tttattcatc atgacttcaa ttttatttaa aaataaattt tttaaatatg
     6661 gatttttaat attttttaaa taatgagtat caactttatt actcgaaaaa ggtatatctt
     6721 ttatataact acttatataa cttaattctc ttttaaatct ttgaacttct ttactttctt
     6781 caacttcatt tatactgatg attatattat ttaaatcatg attaaatttt tgaatttcta
     6841 gattcttttt ttctatcaat tgtgagtaaa aatttatatt ttcaaatttt atttcattgt
     6901 ttctttttaa ttcttgttct ttttgtactc tattttcata aaaaataaga aaaaatataa
     6961 aagtaccttg cattattaca aaaaacaaaa gtaaatcaat gaatctttca aaataataga
     7021 ttttattgaa aatataagtt ataaagaaaa tggataagta tatatacaat aaaagtaaag
     7081 ttaatgataa gcttacaaat gaatagatat acgttgaaaa attgtatttt ttaaaaattt
     7141 ttatatataa tatcacctga attgatatga ttaataattg gagataaact aaataatcac
     7201 cagatatccc tgtaacatta taaatatata ttatgatgta agaactattt atattgataa
     7261 atttaatgct tataaaaaat attagtatta cattcaattt atttaagtct ttatgtaaaa
     7321 atatataata aatggcaata cagactacaa aaaagatttc tataaaatct cctaaaaata
     7381 ttgaaaaaat aaaccaaata aggagcccta tgaaagctat ttttagtttc tcagggctct
     7441 ttgtttgaaa gtatatttta tagaaaaaat acgtataaat aagaatagat aaaaacattc
     7501 taagaatgta tagcttagta tcaatgatca tttttgtatt ccttaacagt ttttaaagaa
     7561 tgaaagtata cattttttta tatcaccttt aggttgtcca ggaagtgtat aattacctcc
     7621 gctaccacca tttataatta acaattgtgg aatatctaat tgtttcattg gtctccctca
     7681 cttttctcat tttataaaca atataacatt aagtatagaa tattataaag gatatcttga
     7741 attgatcttt ttttactcat aaatgaatgt ttttcttatt tatagaggtg taggttatat
     7801 ttttaatgtt tcatgcatag ttttattttt ttcactttat tactttatac tactatctga
     7861 aattattttt tgaaaggaaa acaaatgaaa aaaataccct ttatccaaca agaagatgca
     7921 aaagattgtg gtcctgtatg tatcgcgatg atatgtaaat tttataataa aaaagtatca
     7981 atagaaaagc ttagaaaaat ttctggtacc gacaacaatg gtactaacct atttggcctt
     8041 atagaacttg ggcaatattt agggcttgaa ctcagcggag tacaggcgga aagtacaaaa
     8101 aatctatatg aaatccatta tccgtgtata gcgcacataa ttaataaaaa agggagcgaa
     8161 cactttgtta taattgaaaa agttttaaat gataaagttt atattgtaga tcctgatatt
     8221 ggtagatatt ctacatcttt aaatcaattt gatacatact ggactaaaat attacttctc
     8281 atagaaaaaa aagacgattt tactacatat gatgataggc cttccatatc cactttgttt
     8341 cgtagtttaa ttactcataa tagtaaatat ataggattaa taattttatc ttctctatta
     8401 atcaatttat ttggatttct cggtactttt tattttaagt tgctgattga tgatatatta
     8461 cctagtaata tagtatataa ccttcatata ttgtctggat ctatcttact aatgtatctt
     8521 gtccaatcgt tgattacata tttcagatct catctaatac ttttcttaag tctgaaaatt
     8581 gatataaaaa ttatgcttga ttattataat catgtattaa agttacctat gggtttcttc
     8641 gaaacacgta agtctggaga aattctttca agatttatgg atagtaataa aatcagagaa
     8701 gctttttcta ctgttacagt tacgtttttt attgatactt taatgatttt cttaggtagt
     8761 attctactgt atttacaaag tagtagacta ttttttatta ctctaatatt tgtgcctatc
     8821 tatatattat tggcattaat gtttagaaaa ccttttgaaa aatataatcg ccaacaaatg
     8881 gaacaaaatt ctgagcttaa ttcttattta attgaaacca ttaacggtat atccacgata
     8941 aaaagttata ctgcagaaga agaagtatca attaaatcag aaaagttttt cattcgtcta
     9001 attaagaaag ttttaaagtt aggtattata actaacatac agatgagtat aaaaggattt
     9061 ttgtcactat taatcagtac ggttatttta tggataggtt catattatgt tattaataat
     9121 caaatgactt taggcgaact catcacattt aatgcccttg ttgtttattt tttaggtcct
     9181 attgaacgca tgatagatgc ccaacctgtt atacaatcag caatcgttgc gtctagaaga
     9241 attgttgaaa tactcgattt agaagtagag gataaagaaa atgctgtatc agaattctca
     9301 tttaataatc aaatacagat aagtaatcta tattttaact atggtcatcg agaagattta
     9361 ttaaaagata ttaatattac aatacctaaa gatacttttg ttgctttagt aggagaaagt
     9421 ggttccggta agtcaacatt agcgaaactt ctagttaatt actatcaagc aaaacaaggc
     9481 gatattcaga tagatcaaaa gaatatagtc tctattgaaa ataagtcttt aagaaaaaac
     9541 ataggctatg tatcacaaaa gaattttttc tttagtgggt caattataga aaacctatta
     9601 ctgggtaatg ataagcatat caccatggat gaaataatat gggcctgtaa aaacgctgaa
     9661 atacatgatt ttattgaaga gttgcctcaa ggatatcaaa ctactttaga agctgatggt
     9721 gataattttt ctgggggaca actacagaga cttgctttag ctagattata tattaaaaat
     9781 cctgaggtct ttatattaga cgaagttaca agtgctttag attctacgac agaaaacaaa
     9841 atcatcaata acttacacag tgtttctaaa aaaggtaaaa cagtaattat catctcacat
     9901 aagttaagta ctattgaaaa agtagataat atttattgtt taaaaaatgg gagaatagtt
     9961 gaacaaggaa atcataagca gttactatca aaccgttcag aatattatac actatggaaa
    10021 aatcaaacaa cggagggaat ataatatgaa aaaaatatac tcctttgaag attttcaaga
    10081 tagtactgtg tatttgaata attctccttc aaagttcata acaagatcgc tcataatact
    10141 cttcataata tttatggccg ttattatttc tatatttttt attaaaaaaa ctgattatat
    10201 taaatccacg gctgtaataa caccaaaaaa taatcctatt aatattacaa cagataagga
    10261 tattaaagtt aaaaagctgc taaaagataa tggagaatta gtacagcaaa aggagaaagt
    10321 tattactatt caagatataa ataatgataa gaaacagata acttctaaaa taaaatataa
    10381 aaaggagtcg ttaaaggatt tatcattact ctatgataaa atagacaact atcctttaga
    10441 atcagataaa aaactgcata ctgattatag tgaaaagtac tttgaaagct ataaaaaaca
    10501 atataatcaa acagactacc tagataattc acaacgtaac aacattaaat ctcaaagcct
    10561 tcaaattcta attgaaaaaa taaatactct aaaagatgag ttacacgagt tatccgtaat
    10621 taagggaaat gacaatcagg attatgtaac caagaatggt tatatttttt accctaaaga
    10681 agtacaagaa ggattaataa ttcctaaagg taaattgctc tatcaaattt acaaaaatag
    10741 agataaagaa gtagttacat atatttcgag tgaagatatt ttaagcttaa atcctaatca
    10801 aaaagtctca attacattta aaacaaaaaa agatgaattc taccttcagg ggaatattaa
    10861 atatatttcg aaattccccg aagaatcaaa aaataatgaa acattttaca aagtaaaaat
    10921 ttcactgaaa gataaaattc ctaagcaact tgaaaatgta tattacctta aaggtacctc
    10981 gtatgttgaa ctagaaaaag agacaatagc tcaatatctg tatcgtaaaa taaaagaata
    11041 aaaaataagt gtctaacggt tctgttgcaa agttaaaaaa taagtgtcta accttatgtt
    11101 taaaataata cttcgtatta actagctagc atgatgctaa ttacacggca tggcgaaaac
    11161 ccgtagatct gaagagatct gcggttcttt ttatatagtc cataaataca ttcaatgcct
    11221 ttgatcgtat tctttgccgt attgatactt tgataactta ttttccttac tttgatatga
    11281 cgatgatctt gttcaatgag attatttaaa tatttagagg tacaatgaca gttgggggta
    11341 agtttaaaat ctttaatcac tttggacatt gccaccttcg ttgaaggggc ttggtctgta
    11401 attatcattt gaggtttgcc aaattgttta ataagacgtt taataaacgt atatgctgag
    11461 tgattatctc gtttcttacg taacgaaata tctagtgtat ggccatctgc atcaatagcg
    11521 cgatataaat aatgccattg ccctttaatt ttgatatacg tctcgtctat atgccattta
    11581 taataagctt gcttattctt tttcttccaa atttgataca aaataggagc atattcctgt
    11641 acccatcgat aaattgttga atgatgaaca tagatgcctc gttctctcaa tatttcagat
    11701 atatcacgat aacttaatgc atatcttaga tagtagccaa cggctacagt aatgacatct
    11761 ttgtcaaatt gcttatatct gaaataattc atcctctgca cctcattttt gttgactatt
    11821 atactatatt tctaactttg caacagaacc ttcttttctc tccatgggcg ctgtttccca
    11881 tttttcatca tatcttttaa tgttttatta tcttgatttt cgtctatata tctagtagta
    11941 ttgtattgca tataaaaaga cctccagtat tgatttagat tagacacctt aatcatatta
    12001 ctggagtttt tttatgtcaa attttatttt ccccacggaa aacagtatga aacgccgtca
    12061 tatcaacgct tcaaaaggat tttagaaaag aacgttattt ctatatagta tcaagacaag
    12121 aagaaactcg tttcaaaaac cctcatgatt tttagagaaa aactctctta tttcatcgtc
    12181 tttaataaaa taatatgcca tctttccatc tttataaaaa tcaagtacct catttttata
    12241 taaaagcctt aaatgatgtg aagttgaagc aacactcatt ttcaatatca aagaaatatc
    12301 acaaacacac aactcatctt ctttaatcaa agataatatg attttcaatt tcttctcatc
    12361 acaaattttt tctaaaatgt taagtaattt cttagattta tcatcttcta aaaaacttaa
    12421 agcattgtta actttatcct catgtacaca aatcacatca caagtatttt cataattcat
    12481 ataaaatcac accctaaatt aaaatataaa tcctaaaatt gtttgaatag tgtcattttc
    12541 aataataata aataaaccta aagctatata aataatagcc ataatccaac gactaaattt
    12601 ctcaacaatt tctccaattc ctgggatatt agctaatttt tgtgcagtaa acaccaagaa
    12661 gaaaattaaa attaaaaaga caaacagagt aagtaataaa ttagtaacac ttaatgtcac
    12721 aaaatacgga acaaataaac caatattatc ggcgccacaa cttgctatcg taacaattgc
    12781 aaccgtacca actaatttag acaatccttt ttcattcaat tcttttttag ctctcttttc
    12841 tccttcacaa tcatcataaa tagccacttt aattccaaga taaattggta ttaaacccaa
    12901 taaacctaat atccactttt ctggaacata atttaataca aaagctaaaa acaaactaac
    12961 taatattaaa ataatagacc ctaaatattg accaacataa atatctctat attcttttct
    13021 agtctttgct ctagcaaaaa atattaataa aattactaat aaatcaactg ctgtagcaat
    13081 ataaagaaca gcagcagcaa caaccgtttg aatcataata cacctcattc aaaaatattt
    13141 ttgaatgtat tataacttat atttttaaat aatcataggt gctttattcc aattgcttta
    13201 ttgacgttga gcctcggaac ccttaacaat cccaaaattt gtcgaatggt cggcttaata
    13261 gctcacgcta tgccgacatt cgtctgcaag tttagttaag ggttcttctc aacgcacaat
    13321 aaattttctc ggcataaatg cgtgtctatg cgtagacatg gagacacttc agaattatgg
    13381 agtgattaca tgagtttaac tatttttctt tattaagttt taggaagttt attagcaaat
    13441 tatatctacg aaaaatcttc gaaataaata actttttcgg gtctactttg tacactttat
    13501 ctacctggta gacccaatgt tattgcttta caggtctaaa attcgtcgtt ataatctagt
    13561 taaatcccgt aagggcgcac ttatacgtcg gataaatcga cgtgtacaaa aacgtaatcg
    13621 accttcgtcg atttttttta tttcaaaatt aaagaaacgg cttgagatat tccgagcagt
    13681 tataaaaatt aatttgcgtt gaatattgct actacattct tgaaaaagtg atgtagattt
    13741 atagcccata acttttttga attacatcga cgatacggcg tcgaaagaaa aataaataga
    13801 ccgtatgaaa gaaaaagcta cctcacttta tctgggatag cttttatttt ttatgccctt
    13861 attttgaatt ttaagagggc attttaaaga tttaggggtg attcatatag ttttattatc
    13921 taaaacttat atacgctttt aaaacgcaaa tatgagccaa ataaatatat gctattttca
    13981 aaaacaaaaa tttgagcaaa aacaataact attttttaga cactgcccat ttacatgcaa
    14041 attaaaaatt agcataaaat tctttaaaac ttccccacgt ttttctaaat tcctgcaggg
    14101 cttttcttat caaaaactta gaaattttaa tttaactcta aaatctccgt aagagcataa
    14161 gggaaatttg ctatcattca aaaatgatag gtctggcaaa gccagacatt ccaagggttt
    14221 taagtaattt taaagtgata tcatacaaag ctgtagtgtc acacttttgt gacactacat
    14281 acagcatttg tcacaaaaat aagacagtac ttttttacaa aaaaatcaac aaaaaagaca
    14341 tcagttatca ctaatgtctt aaataataat tttgcttttc gaaattccaa attgcggtaa
    14401 ttgaatgtgc tttttttctt cgtctgtcgt tttatcttca tcacttgtat taatcaaatt
    14461 accatcttcg gcatcgtcta agtttaaaat tttatgcttt tgtttaagca atccaccata
    14521 acttaacata cgttttcgat acaaaccttt ttctaaatca cttaaaattt cttggttttt
    14581 ttcgtcgtca tcagttaaaa agtcagatga tttaacggaa tattttgatg tctcttcgag
    14641 tgttataaaa tcatttgaat tattgattaa agatattata ttgtttcatg tttttacggc
    14701 gcatataaag ggcatgtgtt tcttcaagtt cagttagaat tgtttgcatt aaataagctt
    14761 gcattgactt gattgtttcc ttttggcctt taactcctct gtcatgtata gcttttttaa
    14821 gtctttttaa agaagttaat atttcatcct caatgtcttc taacatgtaa tgcatatctt
    14881 catgccttga attaaatgat ttttttgctt taagaataac agcctttatg atttctaaat
    14941 ctctataatc atattttaat aaataattag ttagttgttc tgggaattct tgcaatagca
    15001 tttctttatc atcaaaatta tgtgtaaatt gatttgaatg attt
//
