LOCUS       NZ_CP095524.1          15287 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP095524.1 Escherichia coli strain GN04171 plasmid p4171-2.
ACCESSION   NZ_CP095524
VERSION     NZ_CP095524.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-06-07 17:47:43
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 59031
            Orig. end    :: 74318
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15287
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:11990]"
                     /cutoff="20000"
                     /detection_rule="((((goadsporin_like or PF00881 or
                     TIGR03605) and (YcaO or TIGR03604)) or TIGR03882 or
                     TIGR03603 or TIGR03602) and not cyanobactin_synth)"
                     /neighbourhood="10000"
                     /product="LAP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11990
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((((goadsporin_like or PF00881 or
                     TIGR03605) and (YcaO or TIGR03604)) or TIGR03882 or
                     TIGR03603 or TIGR03602) and not cyanobactin_synth)"
                     /neighbourhood="10000"
                     /product="LAP"
                     /protocluster_number="1"
     cand_cluster    1..15287
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((((goadsporin_like or PF00881 or
                     TIGR03605) and (YcaO or TIGR03604)) or TIGR03882 or
                     TIGR03603 or TIGR03602) and not cyanobactin_synth)"
                     /kind="single"
                     /product="LAP"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15287
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="LAP"
                     /region_number="1"
                     /rules="((((goadsporin_like or PF00881 or TIGR03605) and
                     (YcaO or TIGR03604)) or TIGR03882 or TIGR03603 or
                     TIGR03602) and not cyanobactin_synth)"
                     /tool="antismash"
     CDS             1193..1456
                     /locus_tag="ctg1_69"
                     /transl_table=11
                     /translation="MNSTTHYENANFLRELAESLPRIFPEGSTDKSALLQRLANEELAR
                     AEYDEQIRAKVAAARADKRPGMSSAQLRQQLQGRYQELRNEL"
     CDS             1446..1745
                     /locus_tag="ctg1_70"
                     /transl_table=11
                     /translation="MSYEIEWRPGAIEDITALFEYLVENASLWDARNVTERLITATDRL
                     ADYPRLYETDERYGEGVRRISLLGQHVLYEVNDEASRVNILAVVGQRQNPRFIL"
     CDS             complement(1781..2446)
                     /locus_tag="ctg1_71"
                     /transl_table=11
                     /translation="MMFWNRNKKDKATIANEKKRFNHLLSVAEKLPVKALPDLIRAIVR
                     PVQSDFLLAVAEEGTDARPDMTPQEFFFKGLTQIQSYEKMKECEMNGADYPLSLASDIV
                     LPWPWSLPRYIDNVSRIGTHKGKPWKQDKNNHYVDLWLPWRIGFVHGGNHSITAGILAG
                     EGSLIPEHVYDMSWMFELVRTDGNNWFVEGQKAEAVKSGRSAAVFEIGRLLVEGAKER"
     CDS             complement(2634..3494)
                     /gene_functions="resistance (resist) TEM (Score: 673.2;
                     E-value: 2e-205)"
                     /gene_kind="resistance"
                     /locus_tag="ctg1_72"
                     /transl_table=11
                     /translation="MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYI
                     ELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYS
                     PVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRW
                     EPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSA
                     LPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAS
                     LIKHW"
     CDS             complement(3677..4234)
                     /locus_tag="ctg1_73"
                     /transl_table=11
                     /translation="MRLFGYARVSTSQQSLDLQVRALKDAGVKANRIFTDKASGSSTDR
                     EGLDLLRMKVEEGDVILVKKLDRLGRDTADMIQLIKEFDAQGVAVRFIDDGISTDGDMG
                     QMVVTILSAVAQAERRRILERTNEGRQEAKLKGIKFGRRRTVDRNVVLTLHQKGTGATE
                     IAHQLSIARSTVYKILEDERAS"
     CDS             4398..7403
                     /locus_tag="ctg1_74"
                     /transl_table=11
                     /translation="MPVDFLTTEQTESYGRFTGEPDELQLARYFHLDEADKEFIGKSRG
                     DHNRLGIALQIGCVRFLGTFLTDMNHIPSGVRHFTARQLGIRDITVLAEYGQRENTRRE
                     HAALIRQHYQYREFAWPWTFRLTRLLYTRSWISNERPGLLFDLATGWLMQHRIILPGAT
                     TLTRLISEVREKATLRLWNKLALIPSAEQRSQLEMLLGPTDCSRLSLLESLKKGPVTIS
                     GPAFNEAIERWKTLNDFGLHAENLSTLPAVRLKNLARYAGMTSVFNIARMSPQKRMAVL
                     VAFVLAWETLALDDALDVLDAMLAVIIRDARKIGQKKRLRSLKDLDKSALALASACSYL
                     LKEETPDESIRAEVFSYIPRQKLAEIITLVREIARPSDDNFHEEMVEQYGRVRRFLPHL
                     LNTVKFSSAPAGVTTLNACDYLSREFSSRRQFFDDAPTEIISRSWKRLVINKEKHITRR
                     GYTLCFLSKLQDSLRRRDVYVTGSNRWGDPRARLLQGADWQANRIKVYRSLGHPTDPQE
                     AIKSLGHQLDSRYRQVAARLCENEAVELDVSGPKPRLTISPLASLDEPDSLKRLSKMIS
                     DLLPPVDLTELLLEINAHTGFADEFFHASEASARVDDLPVSISAVLMAEACNIGLEPLI
                     RSNVPALTRHRLNWTKANYLRAETITSANARLVDFQATLPLAQIWGGGEVASADGMRFV
                     TPVRTINAGPNRKYFGNNRGITWYNFVSDQYSGFHGIVIPGTLRDSIFVLEGLLEQETG
                     LNPTEIMTDTAGASELVFGLFWLLGYQFSPRLADAGASVFWRMDHDADYGVLNDIARGQ
                     SDPRKIVLQWDEMIRTAGSLKLGKVQVSVLVRSLLKSERPSGLTQAIIEVGRINKTLYL
                     LNYIDDEDYRRRILTQLNRGESRHAVARAICHGQKGEIRKRYTDGQEDQLGTLGLVTNA
                     VVLWNTIYMQAALDHLRAQGETLNDEDIARLSPLCHGHINMLGHYSFTLAELVTKGHLR
                     PLKEASEAENVA"
     CDS             complement(7971..8534)
                     /locus_tag="ctg1_75"
                     /transl_table=11
                     /translation="MDIIEKRITKRHLSESELSGVNYYNCIFERIQLDNFNFRDCEFEK
                     CRFVNCSIKNLKLNFFKLIDCEFKDCLLQGVNAADIMFPCTFSLVNCDLRFVDFISLRL
                     QKSIFLSCRFRDCLFEETDLRKSDFTGSEFNNTEFRHSDLSHCDFSMTEGLDINPEINR
                     ILSIKIPQEAGLKILKRMGVVVGG"
     CDS             complement(8538..9269)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 95.1; E-value:
                     9.3e-29)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_76"
                     /transl_table=11
                     /translation="MTIPLLEINSLSFSYKVNLPPVFNNLSLKIEQGELIGLLGENGAG
                     KTTLFNLIRGGVSNYEGTLKRNFSGGELVSLPQVINLSGTLRNEEVLDLICCFNKLTKK
                     QAWTELNHKWNDNFFIRYDKIRRKRTYTVSYGEKRWLIISLMLTLCKNARLFLLDEPTV
                     GIDIQYRMMLWELINKITADGKTVFFSTHIFDELTRDKIPFYMLSKNSINRYSDMSDFI
                     QSNNETTPEKAFIKEVMGTGD"
     CDS             complement(9266..9991)
                     /locus_tag="ctg1_77"
                     /transl_table=11
                     /translation="MVTLKMAIIFLMEQIRTPFSLIWTIMSPTVLFFFLHFNEIELHYG
                     DTAWLGKQISWFVGYISFSVVLFNYCLYLVGRRESGFIATFVHNMDGRLLFIRSQLIAS
                     LIMSILYVFFFILVVLTGFQASPDYQIVMIILKSIYINAFMMVSLTFMASFRVTFQTTS
                     TIYSVLITVCMVSGIVSLKYNEGIVYWINQVNPIAIYSTILQSDQELSLMTIFFYSIML
                     IISIISALTFKTEPVWSSQ"
     CDS             complement(10001..11191)
                     /gene_functions="biosynthetic (rule-based-clusters) LAP:
                     YcaO"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_78"
                     /sec_met_domain="YcaO (E-value: 1.1e-16, bitscore: 53.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINVYSNLMSAWPATMAMSPKLNRNMPTFSQIWDYERITPASAAG
                     ETLKSIQGAIGEYFERRHFFNEIVTGGQKTLYEMMPPSAAKAFTEAFFQISSLTRDEII
                     THKFKTVRAFNLFSLEQQEIPAVIIALDNITAADDLKFYPDRDTCGCSFHGSLNDAIEG
                     SLCEFMERQSLLLYWLQGKANTEISSEIVTGINHIDEILLALRSEGDIRIFDITLPGAP
                     GHAVLTLYGTKNKISRIKYSTGLSYANSLKKALCKSVVELWQSYICLHNFLIGGYTDDD
                     IIDSYQRHFMSCNKYESFTDLCENTVLLSDDVKLTLEENITSDTNLLNYLQQISDNIFV
                     YYARERVSNSLVWYTKIVSPDFFLHMNNSGAININNKIYHTGDGIKVRESKMVPFP"
     CDS             complement(11172..11990)
                     /gene_functions="biosynthetic (rule-based-clusters) LAP:
                     PF00881"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_79"
                     /sec_met_domain="PF00881 (E-value: 9e-10, bitscore: 31.3,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKHELSLVEVTHYTDPEVLAIVKDFHVRGNFASLPEFAERTFVS
                     AVPLAHLEKFENKEVLFRPGFSSVINISSSHNFSRERLPSGINFCDKNKLSIRTIEKLL
                     VNAFSSPDPGSVRRPYPSGGALYPIEVFLCRLSENTENWQAGTNVYHYLPLSQALEPVA
                     TCNTQSLYRSLSGGDSERLGKPHFALVYCIIFEKALFKYRYRGYRMALMETGSMYQNAV
                     LVADQIGLKNRVWAGYTDSYVAKTMNLDQRTVAPLIVQFFGDVNDDKCLQ"
     CDS             complement(11992..12846)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04424"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_80"
                     /sec_met_domain="TIGR04424 (E-value: 2.3e-88, bitscore:
                     288.9, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINILPFEIISRNTKTLLITYISSVDITHEGMKKVLESLRSKQGI
                     ISEYLLDKLLDESLIDKDKGKEFLITTGVINKTKTSPLWVNSVIISDVPHLFSNAREQW
                     KSDGVFVSHIIDIKDNNINVSDSTLIWLHLENYHSDIVKRIYSKFESNPGVAFIQSYYL
                     KESFRIDGVYSPDLGTPCHFCHIERWLSREEKSFRRNEMSWANLLQLLKKYQMTLPALA
                     LGESERGFSYHLIKRRLQELTGTSLVKSHVDNFMSSVSADLITCILCKEPVIHWQACSC
                     LER"
     CDS             complement(12906..13115)
                     /locus_tag="ctg1_81"
                     /transl_table=11
                     /translation="MELKASEFGVVLSVDALKLSRQSPLGVGIGGGGGGGGGGSCGGQG
                     GGCGGCSNGCSGGNGGSGGSGSHI"
     CDS             13645..14097
                     /locus_tag="ctg1_82"
                     /transl_table=11
                     /translation="MKFMECAVRDVIYGTNVRIVKPVNIYECELRDNVFVGPFVEIQKG
                     CVIGSGSRIQSHTFICENVTLGENCFIGHNVTFANDLFRSGAPDPSPDNWISITLGDSV
                     TVGSGAIILSPYICSGAVIGAGAVVVKPIENKGIYAGNPARLIRIL"
     CDS             complement(14500..14853)
                     /locus_tag="ctg1_83"
                     /transl_table=11
                     /translation="MMDKRRTIAFKLNPDVNQTDKIVCDTLDSIPQGERSRLNRAALTA
                     GLALYRQDPRAPFLLCELLTKETTFSDIVNILRSLFPKEMADLNSSTIIQSSSQSEQKS
                     DEETKKNAMKLIN"
     CDS             complement(14853..15287)
                     /locus_tag="ctg1_84"
                     /transl_table=11
                     /translation="MFLKVMGKLSGISKIYGDSSLGVSLVTSAVKDALSLARTKGSSYL
                     ADDIIIHRKDNNYLKQRINDENKISIVTEAMNEALRKLEQRVLNTLNEFSGYTHVMVIG
                     GGAELICDAVKKHTQIRDERFFKTNNSQYDLVNGMYLIGN"
ORIGIN
        1 gcggaagggc gcttcactgc caatcgtgag gcggtaaaac gcgaagttga gcgtcgtgtg
       61 aaggagcgca tgattctgtc acgtaaccgt aattacagcc ggctggccac agcttccccc
      121 tgaaagtgac ctcctctgaa taatccggcc cgcgctggag gcattcgcac gcctgaagcc
      181 cgtcgatgca caaaaaaaca gcaccacata caaaaaacaa cctcatcatc cagcttctgg
      241 tgcatccggc cccccctgtt ttcgatacaa aacacgcctc acagacgggg aattttgctt
      301 atccacatta aactgcaagg gacttcccca taaggttaca accgttcatg tcataaagcg
      361 ccagccgcca gtcttacagg gtgcaatgta tcttttaaac acctgtttat atctccttta
      421 aactacttaa ttacattcat ttaaaaagaa aacctgttca ctgcctgtcc tgtggacaga
      481 cagatatgca cctcccaccg caagcggcgg gccccgaccg gagccacttt agttacaaca
      541 cacaaaaaca acctccagaa aaaccccgga ccagcgcaga actggagccg caaagcccct
      601 ccctcataac tgaaaagcgg ccccgccccg gcccgaaggg ccggaacaga gtcgctttta
      661 attatgaatg ttgtaactat actccgtcat cgctgtcagt gttctggctg gaagtcctca
      721 gtacacgctc gtaagcggcc ctgacggccc gctaacgcgg agatacgccc cgacttcggg
      781 taaaccctcg tcgggaccac tccgaccgcg cacagaagct ctctcatggc tgaaaacagg
      841 tatggtctgg cagggcaagg gatgggtaag gtgaaatcta tcaatcagta ccggctgacg
      901 ccgggcttcg gcggttttac tccggtatca catgtaacca cagcgtgccg ccttccatgc
      961 cgctggcgcg gcataagcat atgttggtgg ctgtgtctga aaggttatat actctgcata
     1021 aaacctgaca acacgcagat tgccaggcaa atgagcatta tgcatccggt tatcgcctgc
     1081 ctgtgaaaca atatcaccgg ggcgaatatc gatactctga ctcgttatac ccatgcgtgt
     1141 ggcatcaaaa aacctgcaat tgccctttat tgaatgaaag ggggagtcaa ttatgaatag
     1201 caccacacat tacgaaaacg ccaatttcct gcgcgagctg gccgaaagcc tgcctcgtat
     1261 ttttccagaa ggcagtacag acaagtctgc actattgcaa cgcctcgcta atgaagaact
     1321 ggcacgggcg gaatacgacg aacagatccg agcgaaagtt gccgctgccc gcgccgataa
     1381 gcggccggga atgagttccg cgcaactgcg ccagcaacta cagggacgtt atcaggaact
     1441 gcgcaatgag ttatgaaata gaatggcgac caggtgcgat tgaggatata acggcgttgt
     1501 ttgaatatct ggtcgagaat gcatctcttt gggatgcaag gaacgtgaca gagcgtctga
     1561 tcactgcaac cgatcgcctg gctgattacc ccaggctgta tgaaacggat gaacgctatg
     1621 gtgaaggggt tcgccgtatt agcttacttg gacagcatgt actttatgaa gtgaatgatg
     1681 aggccagtcg tgtcaatatc ctggcggttg taggccagcg tcagaatccc cgattcattc
     1741 tttgagtgtc cggcttggaa ctccatcttc agagaatcga tcaacgttct ttagctcctt
     1801 ccactaacag ccgacctatc tcaaacaccg cagctgaccg tcccgacttc accgcttcgg
     1861 ctttctgtcc ctcaacaaac cagttattac cgtccgttcg gaccaactca aacatccatg
     1921 acatatcgta aacgtgttcc gggatcagcg acccttctcc ggccagaata cccgccgtta
     1981 tggagtggtt gcccccgtgc acaaagccaa tacgccaggg caaccacagg tcaacatagt
     2041 ggttgttttt atcttgcttc cacggcttcc ccttatgggt tccaatgcgt gaaacgttat
     2101 cgatatagcg tggtaggctc caaggccacg gcagcactat gtcgcttgcc agcgacaacg
     2161 gataatcagc gccgttcatc tcacactctt tcatcttttc gtaagattgt atttgggtaa
     2221 gtcccttaaa gaagaactcc tgcggggtca tatccgggcg ggcatctgtt ccctcctcag
     2281 ctaccgccag caagaaatca ctctgtactg gccgcacgat agcgcgaatg agatctggta
     2341 gcgccttaac gggtagtttc tctgccacag aaagcagatg attgaagcgt tttttttcat
     2401 tggctatagt tgctttatct ttcttgtttc ggttccagaa catcactgtc tgtagccctc
     2461 cttatcgtga tcaggatgat ggttttgggg tctgacgctc agtggaacga aaactcacgt
     2521 taagggattt tggtcatgag attatcaaaa aggatcttca cctagatcct tttaaattaa
     2581 aaatgaagtt ttaaatcaat ctaaagtata tatgagtaaa cttggtctga cagttaccaa
     2641 tgcttaatca gtgaggcacc tatctcagcg atctgtctat ttcgttcatc catagttgcc
     2701 tgactccccg tcgtgtagat aactacgata cgggagggct taccatctgg ccccagtgct
     2761 gcaatgatac cgcgagaccc acgctcaccg gctccagatt tatcagcaat aaaccagcca
     2821 gccggaaggg ccgagcgcag aagtggtcct gcaactttat ccgcctccat ccagtctatt
     2881 aattgttgcc gggaagctag agtaagtagt tcgccagtta atagtttgcg caacgttgtt
     2941 gccattgctg caggcatcgt ggtgtcacgc tcgtcgtttg gtatggcttc attcagctcc
     3001 ggttcccaac gatcaaggcg agttacatga tcccccatgt tgtgcaaaaa agcggttagc
     3061 tccttcggtc ctccgatcgt tgtcagaagt aagttggcag cagtgttatc actcatggtt
     3121 atggcagcac tgcataattc tcttactgtc atgccatccg taagatgctt ttctgtgact
     3181 ggtgagtact caaccaagtc attctgagaa tagtgtatgc ggcgaccgag ttgctcttgc
     3241 ccggcgtcaa cacgggataa taccgcacca catagcagaa ctttaaaagt gctcatcatt
     3301 ggaaaacgtt cttcggggcg aaaactctca aggatcttac cgctgttgag atccagttcg
     3361 atgtaaccca ctcgtgcacc caactgatct tcagcatctt ttactttcac cagcgtttct
     3421 gggtgagcaa aaacaggaag gcaaaatgcc gcaaaaaagg gaataagggc gacacgaaaa
     3481 tgttgaatac tcatactctt cctttttcaa tattattgaa gcatttacca gggttattgt
     3541 ctcatgagcg gatacatatt tgaatgtatt tagaaaaata aacaaatagg ggttccgcgc
     3601 acatttcccc gaaaagtgcc acctgacgtc taagaaacca ttattatcat gacattaacc
     3661 tataaaaata ggcgtatcac gaggcccttt cgtcttcaag aattttataa accgtggagc
     3721 gggcaatact gagctgatga gcaatttccg ttgcaccagt gcccttctga tgaagcgtca
     3781 gcacgacgtt cctgtccacg gtacgcctgc ggccaaattt gattcctttc agctttgctt
     3841 cctgtcggcc ctcattcgtg cgttctagga tcctccggcg ttcagcctgt gccacagccg
     3901 acaggatggt gaccaccatt tgccccatat caccgtcggt actgatcccg tcatcaatga
     3961 accggactgc cacgccctga gcgtcaaatt cctttatcag ttggatcata tcggcagtgt
     4021 cgcggccaag acggtcgagc ttcttaacca gaatgacatc accttcctcc accttcatcc
     4081 tcagcaaatc cagcccttcc cggtctgttg aactgccgga tgccttatcg gtaaatatac
     4141 ggtttgcttt cacacctgcg tctttgagtg ctctgacctg aagatcaaga gactgctgac
     4201 tggttgagac ccgagcgtaa ccaaaaagtc gcataaaaat gtaccttaaa tcgaatatcg
     4261 gacaactcat gtctattatt acaaatttac gatttaatag acatattaat gtaacagttt
     4321 tacgatgtcc gataatttat aacatttcgt acggttggaa aaatgttact aaatgcccgt
     4381 caggcaggga ggccgatatg cccgttgact ttctgaccac tgagcagact gaaagctatg
     4441 gcagattcac cggtgaaccg gatgagcttc agctggcacg atattttcac cttgatgaag
     4501 cagacaagga atttatcgga aaaagcagag gtgatcacaa ccgtctgggc attgccctgc
     4561 aaattggatg tgtccgtttt ctgggcacct tcctcaccga tatgaatcat attccttccg
     4621 gcgtccggca ttttaccgcc agacagctcg ggattcgtga tatcaccgtt cttgcagaat
     4681 acggtcagag ggaaaatacc cgccgtgagc atgcagcgct gatacgtcag cactatcagt
     4741 atcgtgaatt tgcctggccc tggacatttc gccttacccg tcttttatat acccggagct
     4801 ggataagcaa cgaacgtcct ggcctgcttt tcgatctggc gacagggtgg cttatgcaac
     4861 atcgtattat tctccccgga gccactacgc tgacccggtt gatttcagag gtaagggaaa
     4921 aggcgacgtt gcgcctgtgg aacaaactgg cactgatacc gtcagccgaa cagcgttcac
     4981 agctggagat gctgctgggg ccaactgatt gcagccgcct gtctttactg gaatcactga
     5041 aaaagggccc tgtgaccatc agtggtccgg cgtttaatga agcaattgaa cgctggaaaa
     5101 ctctgaacga ttttggcctg catgctgaaa acctgagtac actcccggct gtgcgcctga
     5161 aaaatctcgc acgttatgct ggtatgactt cggtgttcaa tattgccagg atgtcaccgc
     5221 agaaaaggat ggcggttctg gttgcctttg tccttgcatg ggaaacgctg gcgctggatg
     5281 atgcattgga cgttctggac gccatgctgg ccgttatcat ccgtgacgcc agaaagattg
     5341 ggcagaaaaa acggctccgc tcgctgaagg atctggataa atctgcattg gcgctcgcca
     5401 gcgcatgttc gtacctgctg aaagaagaaa caccggacga atcgattcgt gctgaggtgt
     5461 tcagctacat cccaaggcaa aagctggctg aaatcatcac gcttgtccgt gaaattgccc
     5521 ggccctcaga cgataatttt catgaagaaa tggtggagca gtacgggcgc gttcgtcgtt
     5581 tcctgcccca tctgctgaat accgttaaat tttcatccgc acctgccggg gttaccactc
     5641 tgaatgcctg tgactacctc agccgggagt tcagctcacg gcggcagttt tttgacgacg
     5701 caccaacgga aattatcagt cggtcatgga aacggctggt gattaacaag gaaaaacata
     5761 tcacccgcag gggatacacg ctctgctttc tcagtaaact gcaggatagt ctgaggcgga
     5821 gggatgtcta cgttaccggc agtaaccggt ggggagatcc tcgtgcaaga ttactacagg
     5881 gtgctgactg gcaggcaaac cggattaagg tttatcgttc tttggggcac ccgacagacc
     5941 cgcaggaagc aataaaatct ctgggtcatc agcttgatag tcgttacaga caggttgctg
     6001 cacgtctttg cgaaaatgag gctgtcgaac tcgatgtttc tggcccgaag ccccggttga
     6061 caatttctcc cctcgccagt cttgatgagc cggacagtct gaaacgactg agcaaaatga
     6121 tcagtgatct actccctccg gtggatttaa cggagttgct gctcgaaatt aacgcccata
     6181 ccggatttgc tgatgagttt ttccatgcta gtgaagccag tgccagagtt gatgatctgc
     6241 ccgtcagcat cagcgccgtg ctgatggctg aagcctgcaa tatcggtctg gaaccactga
     6301 tcagatcaaa tgttcctgca ctgacccgac accggctgaa ctggacaaaa gcgaactatc
     6361 tgcgggctga aactatcacc agcgctaatg ccagactggt tgattttcag gcaacgctgc
     6421 cactggcaca gatatggggt ggaggagaag tggcatctgc agatggaatg cgctttgtta
     6481 cgccagtcag aacaatcaat gccggaccga accgcaaata ctttggtaat aacagaggga
     6541 tcacctggta caactttgtg tccgatcagt attccggctt tcatggcatc gttataccgg
     6601 ggacgctgag ggactctatc tttgtgctgg aaggtcttct ggaacaggag accgggctga
     6661 atccaaccga aattatgacc gatacagcag gtgccagcga acttgtcttt ggccttttct
     6721 ggctgctggg ataccagttt tctccacgcc tggctgatgc cggtgcttcg gttttctggc
     6781 gaatggacca tgatgccgac tatggcgtgc tgaatgatat tgccagaggg caatcagatc
     6841 cccgaaaaat agtccttcag tgggacgaaa tgatccggac cgctggctcc ctgaagctgg
     6901 gcaaagtaca ggtttcagtg ctggtccgtt cattgctgaa aagtgaacgt ccttccggac
     6961 tgactcaggc aatcattgaa gtggggcgca tcaacaaaac gctgtatctg cttaattata
     7021 ttgatgatga agattaccgc cggcgcattc tgacccagct taatcgggga gaaagtcgcc
     7081 atgccgttgc cagagccatc tgtcacggtc aaaaaggtga gataagaaaa cgatataccg
     7141 acggtcagga agatcaactg ggcacactgg ggctggtcac taacgccgtc gtgttatgga
     7201 acactattta tatgcaggca gccctggatc atctccgggc gcagggtgaa acactgaatg
     7261 atgaagatat cgcacgcctc tccccgcttt gccacggaca tatcaatatg ctcggccatt
     7321 attccttcac gctggcagaa ctggtgacca aaggacatct gagaccatta aaagaggcgt
     7381 cagaggcaga aaacgttgct taacgtgagt tttcgttcca ctgagcgtca gaccccgttt
     7441 tcattctaat ggtgtagtag tttcacgtca cgcgcacgtg catattcttc gaaagcttcg
     7501 gcgttagccg gtcaaccagg ggtttgaggc ccaaccgtac gagatcgtac gctaagttca
     7561 ttttttgagc agaagaggtg agtaaagaaa acgagggttt tatttactct tcccgtcaat
     7621 gccagtagcc atgcggtttc agggactttc agtgttaata aactcggtaa tcaaatcaac
     7681 gtaaacctgc ctaacaacgc cacgacttta ttgacttaaa atcatatagt tagcttctta
     7741 gcgtacgttt ccgctccatt gggcttcaaa ccccacaccc aatgacatga gaaaagctgg
     7801 atctgattct caaaatgctg ggatacccat cgagatggag aactcagtca atgttccatt
     7861 ctttctgaaa tatgtgtggg gacactgatc tgtcgggagc cggatgcggt agttccgcag
     7921 gtccggttct gaggaggggc ccgtccgggc aaccggcggg tctactcacc tcatccccct
     7981 acaaccactc ccattcgttt aagtattttt aaacctgctt cctgtggtat ctttatagat
     8041 aagatcctgt ttatctcagg atttatatcg agaccttctg tcattgaaaa atcacagtga
     8101 gacaaatcag aatgtctgaa ctctgtatta ttaaactccg aaccagtaaa atcagattta
     8161 cgaaggtctg tttcctcaaa taaacaatca cggaagcgac aggataaaaa aatagatttc
     8221 tgtaaccgta aactaataaa atcaacaaat ctcaaatcac aatttacaag agaaaaagta
     8281 cagggaaaca taatgtctgc tgcatttact ccttgtaata aacaatcttt gaattcacag
     8341 tcaataagtt taaaaaaatt aagttttaaa ttctttattg agcagtttac gaagcgacat
     8401 ttttcgaact cacaatcgcg aaagttaaag ttgtcaagct gtattcgttc aaatatacaa
     8461 ttgtaataat ttacacctga taattcactt tcactgaggt gtcgttttgt gattcttttt
     8521 tctattatat ccatgtgtca gtctcctgtt cccataactt ctttaataaa tgccttttct
     8581 ggagttgttt cattattgga ttgaataaaa tcactcatat cagaataacg atttatacta
     8641 ttttttgaaa gcatatagaa ggggatttta tctcttgtta attcatcaaa aatatgagtt
     8701 gagaaaaata ccgttttccc gtcagcggtg atcttattta tcagttccca taacatcatt
     8761 ctgtactgaa tatcaatgcc tacagttggt tcatccagta aaaataaacg ggcatttttg
     8821 caaagcgtta gcatcaaaga tatgataagc caacgcttct ctccataact taccgtgtaa
     8881 gtccttttac gtcttatttt atcatagcga atgaaaaaat tatcattcca tttatgatta
     8941 agctctgtcc atgcctgttt tttagttaac ttattgaagc agcaaatcaa atcaagaacc
     9001 tcctcattcc ttagtgtacc tgaaagattt atgacttgag gtagacttac taattctcca
     9061 ccagagaaat ttcgcttgag ggtcccttca taattactga ctccgcccct gataaggtta
     9121 aaaagagtgg tcttcccggc tccattttct ccaagcagac ctatcaactc tccctgctca
     9181 atcttaagcg acagattatt gaaaacaggg ggtaaattta ctttatatga aaagctcaga
     9241 gagttgattt ctaaaagagg tatggtcatt gagaactcca gactggctca gttttgaagg
     9301 ttagtgctga aataatactt atgattaaca ttatactata gaaaaatatc gtcatcagag
     9361 acaactcctg gtctgactgg agtattgtag aatagatggc gataggatta acctgattta
     9421 tccagtaaac gatcccctca ttatatttta atgatacaat tcctgatacc atacagacag
     9481 ttattaatac agaatagata gtgctggttg tttggaatgt gactctgaac gatgccatga
     9541 aagtgagtga aaccatcata aatgcattta tgtatatcga ttttaaaata atcattacta
     9601 tttgataatc tggacttgcc tggaatcctg ttagtacgac taaaatgaaa aaaaacacat
     9661 acaaaataga catgataagt gaggctatta attgagaacg aataaataat agtcgaccat
     9721 ccatattatg cacgaaggta gcaataaaac cactttctct tcttccgacc agatacagac
     9781 agtaattaaa cagaacaaca gaaaaagaaa tgtagcctac aaaccatgat atttgttttc
     9841 cgagccatgc tgtatcacca taatgaagtt caatttcatt gaaatgaagg aaaaagaaca
     9901 acactgtagg tgacataatt gtccatatta agctgaaagg ggttctgatt tgttccatca
     9961 gaaaaattat cgccattttt aatgtaacca tttgttatcc ttatgggaat ggtaccatct
    10021 ttgattctct gactttaata ccgtccccgg tatggtaaat tttattatta atgtttattg
    10081 cacctgagtt attcatatga aggaaaaaat cagggcttac tatttttgtg taccagacaa
    10141 ggctgttact tactctttcc ctggcatagt aaacaaaaat attatcagaa atttgttgaa
    10201 gatagtttaa taaatttgtg tctgacgtaa tattttcctc aagcgttaac ttgacatcat
    10261 cagacagtag taccgtattt tcacacaaat ccgtaaacga ctcgtacttg ttgcatgaca
    10321 taaagtgacg ctggtaacta tcaataatgt catcatcagt ataaccgcca ataagaaagt
    10381 tgtgcaggca tatatacgat tgccacaatt ccactacgga tttacaaagt gcttttttca
    10441 gactattagc ataggataat ccggtactgt attttattcg actgattttg ttttttgtgc
    10501 catacagggt tagtactgcg tgtccaggag ctccgggcag ggtgatatcg aaaatcctga
    10561 tatctccttc tgacctgaga gccagtaaaa tctcatctat atgatttatg cctgttacta
    10621 tttcactgga tatttcagta ttggcttttc cctgtaacca gtaaagaagg agggactgtc
    10681 tctccataaa ttcacacaag gaaccttcta tggcatcgtt caaactacca tgaaagctac
    10741 atccgcatgt atctctgtca ggataaaatt tcagatcatc tgcagcggtt atattgtcga
    10801 gtgcaattat gactgcaggt atttcttgtt gttcaaggct aaacagatta aaggctctga
    10861 ccgttttaaa tttatgggtt atgatttcat cgcgggtcag tgatgagatc tgaaaaaatg
    10921 cttcggtaaa agcctttgca gcagatggag gcatcatctc atataatgtt ttctgaccac
    10981 cggtgactat ctcattaaaa aaatgacggc gttcaaaata ttcacctatt gccccctgaa
    11041 ttgacttcag agtttcaccg gccgcgctgg ctggtgtaat acgctcatag tcccatatct
    11101 gagaaaacgt tggcatattt ctgttcagtt ttggactcat ggccattgtg gccggccatg
    11161 cggacataag gttactgtag acatttatca tcgtttacat ctccaaaaaa ctgaacgatc
    11221 agtggcgcta cagtcctctg atccagattc attgtttttg ctacgtatga atcggtatat
    11281 cccgcccata cccggttttt cagtcctatt tgatctgcaa ccaatactgc gttctgatac
    11341 atcgaacctg tttccattaa ggccatccgg tatcctctgt agcgatattt gaacaaagct
    11401 ttttcaaaaa taatgcaata gacgagagca aaatggggtt taccaagacg ttccgaatcc
    11461 ccaccggaca ggcttcggta gagtgactga gtattacatg tagcaacagg ttccagtgcc
    11521 tgacttagcg gcaggtagtg ataaacatta gttcctgcct gccagttttc tgtattttca
    11581 gataatctgc ataaaaaaac ttcaatcggg tacaatgccc ccccagaagg ataaggtctt
    11641 cttacagagc caggatcagg tgagctgaat gcattgacta ataacttttc aatagtacga
    11701 atggaaagtt tatttttgtc gcaaaagttt attcctgatg ggagcctttc acgactaaaa
    11761 ttatgtgatg aggatatgtt tattacggag ctgaaacctg gcctgaagag aacttcttta
    11821 ttttcaaatt tctccagatg ggcaagaggt accgcggaca cgaaagttcg ttcagcaaat
    11881 tcggggaggg aagcaaagtt acctctgaca tgaaaatctt taacaatggc cagaacttca
    11941 ggatctgtgt aatgcgttac ttccactaaa gagagttcgt gttttgacat gttatctctc
    12001 cagacagctg caagcctgcc agtgaattac cggctcttta cataaaatac aggtgattaa
    12061 atcagcgcta acagatgaca taaagttatc gacatgactt ttaaccagtg aagtacctgt
    12121 caactcctga agtcgccgtt ttattaaatg atagctgaat cctctttctg attcgcctaa
    12181 agccaatgct ggtagtgtca tttggtattt tttcagtaac tgaagtaagt ttgcccagga
    12241 catttcgtta cgtctgaagc ttttttcttc cctgctcagc catctctcta tatgacaaaa
    12301 atggcaggga gtaccaagat caggtgaata tactccatct atcctgaatg actcctttag
    12361 gtagtagctt tggatgaagg caacaccagg gttactttca aattttgaat agattctttt
    12421 tacaatgtct gaatgatagt tttcgagatg taaccagatt agtgttgaat cgctcacatt
    12481 aatattatta tcttttatat caatgatatg agaaacaaaa acaccatcag atttccattg
    12541 ttcccgggca ttactgaaaa gatgtggaac atcgcttatt atgactgagt ttacccagag
    12601 aggtgatgtt ttcgttttat ttatcacgcc tgtggtaata agaaactctt tgcccttgtc
    12661 tttatcaata agcgattcgt ccagtagttt atcaaggagg tattcagaaa taataccctg
    12721 tttggatcgt aggctttcga gtactttttt cattccctca tgtgtaatgt ctactgaaga
    12781 aatgtaggta ataagcaggg tctttgtatt tctggaaatt atctcaaacg gcagaatatt
    12841 gatcatatct tttccttttt taatatcagg gagcaccatg ctccctgaac ggttaattca
    12901 acgtatcaga tatgtgaacc acttccgccg ctgccaccgt ttccaccact acaaccgttg
    12961 ctgcaaccac cacaaccgcc accttgacca ccgcagctac cgccgccgcc gccgccgcca
    13021 ccaccaccaa tgccaacacc taatggagac tggcgtgata atttaagagc atcaacggac
    13081 aaaactacac caaattcact cgcttttaat tccataagga ctcctttttt aagggaaatt
    13141 aatgcttatg acatctgaat agtatgttgg ccaacactag ttacttgccg taattaacta
    13201 tattttgcaa tgataatttg aactaaattt gtacgcctgt taaatattta ataataatat
    13261 cagttggtta tgtttatgct gttattgttt ttttacaaaa attaatattg tgtttacatt
    13321 ttgctttcag ttgctgtcag gatgtcacac taccccttta agcccccact ggtctggcag
    13381 ggccgggggt gggtaaggtg aaacctgtca atcagtaccg gcttacgccg gtatcatatg
    13441 caacaactga gtgccgcctt ccatatcata tcatttgccc gtttcccgcc gtgcagatcc
    13501 ggtttccggc tgaagtggat ccagacctga tttgttgctg agtatcggta aaagagcggc
    13561 ttataatcta ttctgaaaca tggcaagtga atctgggctg tataattccg gcaagtgtca
    13621 tctgtattta aaggtcgtgt gagtatgaaa tttatggaat gtgctgtccg ggatgtgatt
    13681 tatgggacca atgtccgtat tgtcaaaccg gtcaacattt atgaatgtga actcagggac
    13741 aatgtgtttg tcggcccctt cgttgagata cagaaaggct gtgtcattgg tagtggaagc
    13801 cggatacagt cgcacacgtt tatttgtgag aacgtaacac tgggggagaa ctgcttcatt
    13861 ggtcataacg tgacgttcgc caacgatctg tttcgttcag gagcaccaga tccgtcaccg
    13921 gataactgga tcagcattac cctgggggat tcggttactg ttggcagtgg agccattatt
    13981 ctgtctccgt atatatgcag cggagctgtt attggtgcgg gggcagttgt agtaaaaccg
    14041 attgagaaca aaggcattta tgcaggaaac ccggcaagac tgatcagaat attatgaaaa
    14101 agaaaagggc cgttactggc cctttttatc agaggtaggt ctgtgaatac ggcaggtgta
    14161 cagaaatcga ctgccgggga tcgatttcca gggccgcccg gtattctgcg tcagtgatat
    14221 cacctttttt cagtaaataa ccgagagcat cgtttcccag ccctgacagt atgcgtattc
    14281 tggcgatccg gactggcaaa taacccatca aaaacgttat tgccagacat tgcgaactca
    14341 ccaattttga ttattggagc cactttttca taagttccgt gaaattattt cataataacg
    14401 accctgttta ttttatgtaa tgactggcaa taaaataact tgattaagtt ccctttatcc
    14461 agcctgatag tggataaagg aaactcaatc ataatttaat tagtttatta acttcatcgc
    14521 attctttttt gtctcctcat cacttttttg ctccgattgt gaagaggact gaatgattgt
    14581 tgaagaattt aaatcggcca tctcttttgg aaatagcgat ctcaatatat tcacgatatc
    14641 tgaaaatgtg gtttctttcg tcagcagttc acataaaagg aaaggggccc tgggatcttg
    14701 tctgtataag gccagacctg ccgtcagtgc agcccggtta aggcggctgc gttccccttg
    14761 cgggatactg tccagtgtat cacaaacaat tttatctgtt tgatttacat ctggatttag
    14821 cttaaaggca atggttctgc gcttgtccat cattaattac ctatgagata cataccgtta
    14881 actaaatcat attgagagtt attggtttta aaaaaacgtt catcacgaat ctgtgtgtgt
    14941 ttttttactg catcgcatat taattctgcg ccaccaccta taaccataac atgagtataa
    15001 ccagaaaatt cattgagtgt atttaataca cgttgctcaa gtttacgaag tgcttcattc
    15061 attgcttcgg tgactattga tattttattc tcatcattaa ttcgttgctt cagatagtta
    15121 ttatcttttc tgtgaataat tatatcgtca gcaagatagc tacttccttt tgttctcgca
    15181 agagaaaggg catcttttac tgcagatgtg accagagata caccaagaga tgagtctccg
    15241 tatattttac tgattcccga taatttcccc attaccttga gaaatat
//
