LOCUS       NZ_CP095171.1          11188 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP095171.1 Enterobacter roggenkampii strain K666 plasmid
            pK666_mcr-10, complete sequence.
ACCESSION   NZ_CP095171
VERSION     NZ_CP095171.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-06-07 22:08:07
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 27113
            Orig. end    :: 38301
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11188
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:6188]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..6188
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..11188
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11188
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             complement(1200..1772)
                     /locus_tag="ctg1_33"
                     /transl_table=11
                     /translation="MQYAYIRVSSADQNTARQEEALSKAGFQPDKICVEHASAKDTNRP
                     GLQELLGQLRPGDTLLVHSIDRLCRNMSDMCAVTTRLRDQGVTLIFLKEQLTFSAGTNN
                     PMQELQLHMMSAFSQFERALLKERQADGIAAKKARGEKTGRPGADIKKIQEIDALRSRG
                     VRLRIACDHAGLGVSTYYKLRHQMNNQ"
     CDS             complement(1909..2454)
                     /locus_tag="ctg1_34"
                     /transl_table=11
                     /translation="MVWRRLRIAADTSLAALHFIFQIVQGWGDDHLHQFHIYGKDYGIS
                     YEGGIGFVDNPFRVVIDDFAFDAGDRFTYEYNFFEHWLHDIRVEAIYENSTLKAPFCIS
                     GHGMPGATAADEFDKTLAFLEAIVNADDETTVGEIRPFADDLDAVRFNRHKINRQLSRL
                     DLASPVLEPEVIWLGRRR"
     CDS             2584..2715
                     /locus_tag="ctg1_35"
                     /transl_table=11
                     /translation="MLSVSWGLRSNGTETYDNGINMLYLKCFYLGLTLSGTKTYVKV"
     CDS             complement(2977..3537)
                     /locus_tag="ctg1_36"
                     /transl_table=11
                     /translation="MEINGKKITKRQLNEAKISNASYYNCIFERIQLDNINLRDCEFEN
                     CLFINCSLKTLSLDFFKLIDCEFKNCLLQGVNVSDIMFPCTFSLDNCEMRFIDLVGLRL
                     QKSSFLFTKFRDCLFEETDLRKSDFTGSEFYNTEFRHCDLSRCDFSLTDGLDINHEINK
                     VSSMKIPQDAGFKILKRMGVIIS"
     CDS             complement(3541..4269)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 98.1; E-value:
                     1.1e-29)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_37"
                     /transl_table=11
                     /translation="MTLPLLEINSLSFSYKGHPPVFNNLSLEIKQGGLIGLLGENGAGK
                     TTLFNIIKGGSDNYEGSVKRYFTGGEMVSLPQVINLSGTLRNEEVFDLICCFNKLTKKQ
                     AWAELNSKWNDDFFIRYEKIRHKRTYTVSYGEKRWLIISLMLTLCKDARFFLLDEPTVG
                     IDIQYRMMLWDLINEIAANGKTIFFSTHIFDELTRGCIPFYMLSRNGIKHYTDMDNFMH
                     VNNENTPEKAFIKEIMGAEG"
     CDS             complement(4266..4916)
                     /locus_tag="ctg1_38"
                     /transl_table=11
                     /translation="MSPTVLFFFLHFNEIEQHFGDTLWLKHQISWFVGYISFSVVLFNY
                     CLYLTGRRESGFIATFVHSIEGRLLFIRSQLMASLIMSVMYVLFFITVVFIGFQARPDY
                     QTVILILKTICINVMMMISLTFMASFRVTFQTASTIYSVLITVCMVLGIVSLKYNDGLV
                     YWINIINPIAIYSTLLQPGIELSYITILVYGLMFIISLISALTFKTEPVWSSQ"
     CDS             complement(5001..6188)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: YcaO"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_39"
                     /sec_met_domain="YcaO (E-value: 3.8e-17, bitscore: 56.2,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINVYSHLMSAWPATMVMSPKLNRKMPTFSQVWDYERITPASAAG
                     ETLKSIQGAIGEYFERRHFFNEIVAGSEKTLYEMMDPPAADAFTEAFVQTSSLTEDAVK
                     THRFKTTRAFNLFSLEKQEIPAVIIALDNITAADDLKFYPDRDTCGCSFHGNLNDAMDG
                     ALCEFMERQSLLLYWLQGKANTEISGDVITGINYIDEILVALRAEGELRIFDITLPGAP
                     GHAVLTLYGTTNKCSQIKYSTGLSYAGSLKKALCKSVTELWQSYICMHNFLIGGYTDED
                     IIDSYQRHFMSCNKYESFTDLCENTRLRHKDVILSLENNTLEDDLLSYLEKISSNIFVY
                     YARERISDHLVWYAKIVSPDFFLHMNGSGALNFNNKLYCAGNGIKQRESKMVPFP"
     CDS             complement(6181..6363)
                     /locus_tag="ctg1_40"
                     /transl_table=11
                     /translation="MALMEAGSMYQNAGLVADQIGLRNRVWAGFTDSYVAKTMNVDQRT
                     AAPLIVQFFGDVIDD"
     CDS             complement(7034..7738)
                     /locus_tag="ctg1_41"
                     /transl_table=11
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGPALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
     CDS             complement(8216..9052)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1104:putative esterase (Score: 88.5; E-value:
                     7.8e-27)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_42"
                     /transl_table=11
                     /translation="MELIEQHASSGGWQNVYRHYSQSLNCEMNFGVYLPPKAVTEKLPV
                     LYWLSGLTCTEQNFITKSGMQHYAARHNVIVVVPDTSPRGNNVPDADSYDLGQGAGFYL
                     NATEQPWNVHYRMYDYILRELPDVVMNHFPATARKSISGHSMGGLGALVLALRNPGEYV
                     SVSAFSPIVSPSQVPWGQQAFSAYLGENRKTWEAYDPVSLILQGEKLPEIFIDQGLSDA
                     FYEEQLRTKILERVCNEMNLNASFRYHTGYDHSYYFISSFIGEHIAYHANRLRLSA"
     CDS             complement(9117..9515)
                     /locus_tag="ctg1_43"
                     /transl_table=11
                     /translation="MTTPVISGDGIFSHVFIGAADVEKSSAFYDVVLGTLGINNLGPFG
                     NGWVLYGREKPAFIIARPGNGEAPSANGVTVGFAAATPEEVDAFHAAGLAAGGADEGQP
                     GPRGHLPGAYAAYLRDPAGNKITAYTFI"
     CDS             complement(9559..10668)
                     /NRPS_PKS="Domain: PKS_ER (18-363). E-value: 2.1e-11.
                     Score: 35.4. Matches aSDomain:
                     nrpspksdomains_ctg1_44_PKS_ER.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040:alcohol dehydrogenase (Score: 264; E-value:
                     2.7e-80)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_44"
                     /sec_met_domain="ADH_N (E-value: 5.1e-28, bitscore: 90.5,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 2.4e-22, bitscore:
                     72.7, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSRAAVAFAPGKPLEIVEIDVAPPKKGEVLIKNTHTGVCHTDAF
                     TLSGNDPEGVFPVVLGHEGAGIVVEVGEGVTSVKPGDHVIPLYTAECGECEFCQSGKTN
                     LCVSVRETQGKGLMPDGTTRFSYNGQPLYHYMGCSTFSEYTVVAEVSLAKINPEANHEH
                     VCLLGCGVTTGIGAVHNTAKVQPGDSVAIFGLGAIGLAAVQGARQAKAGRIIAIDTNPT
                     KFDLARQFGATDCINPNDYDKPIKDVLLDINKWGIDHTFECIGNVNVMRAALESAHRGW
                     GQSVVIGVAGAGQEISTRPFQLVTGRVWKGSAFGGVKGRTQLPGMVEDAMKGDIDLEPF
                     VTHTMTLDEINDAFELMHEGKSIRTVIHY"
     aSDomain        complement(9580..10614)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_44_PKS_ER.1"
                     /evalue="2.10E-11"
                     /label="ctg1_44_PKS_ER.1"
                     /locus_tag="ctg1_44"
                     /protein_end="363"
                     /protein_start="18"
                     /score="35.4"
                     /tool="antismash"
                     /translation="EIDVAPPKKGEVLIKNTHTGVCHTDAFTLSGNDPEGVFPVVLGHE
                     GAGIVVEVGEGVTSVKPGDHVIPLYTAECGECEFCQSGKTNLCVSVRETQGKGLMPDGT
                     TRFSYNGQPLYHYMGCSTFSEYTVVAEVSLAKINPEANHEHVCLLGCGVTTGIGAVHNT
                     AKVQPGDSVAIFGLGAIGLAAVQGARQAKAGRIIAIDTNPTKFDLARQFGATDCINPND
                     YDKPIKDVLLDINKWGIDHTFECIGNVNVMRAALESAHRGWGQSVVIGVAGAGQEISTR
                     PFQLVTGRVWKGSAFGGVKGRTQLPGMVEDAMKGDIDLEPFVTHTMTLDEINDAFELMH
                     EGKSI"
     CDS_motif       complement(9868..9888)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_44_0002"
                     /evalue="4.70E+01"
                     /label="PKSI-ER_m2"
                     /locus_tag="ctg1_44"
                     /protein_end="267"
                     /protein_start="260"
                     /score="-2.0"
                     /tool="antismash"
                     /translation="FECIGNV"
     CDS_motif       complement(10453..10491)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_44_0001"
                     /evalue="2.30E-03"
                     /label="PKSI-ER_m2"
                     /locus_tag="ctg1_44"
                     /protein_end="72"
                     /protein_start="59"
                     /score="11.0"
                     /tool="antismash"
                     /translation="LGHEGAGIVVEVG"
     CDS             complement(10703..10978)
                     /locus_tag="ctg1_45"
                     /transl_table=11
                     /translation="MPSTPEEKKKVLTRVRRIRGQIDALERALESGAECRSVLQQIAAV
                     RGAANGLMAEVLESHIRETFDQNDSYSHEVSKSVDDTIELVRAYLK"
ORIGIN
        1 tcgccgtagt ttgggatcat catcttatta ttccggatgt aggtatacat ttcatccaga
       61 tgtttttgca gggatttcag gctaggatag ctgagttcag ggtcatcgca atacataacg
      121 caattatcaa tatgttccag cgcagcgaca acattgccat gccagagata tcgtttaatg
      181 ctttccagca gtgccagaac tttactcccc gcctctggat ctgataccag cagtccccgg
      241 gcatattgca tgagcacctt cagcctcatg gtgatatgaa accagtccag cacatgcgtt
      301 gactcagggt acataccgaa ctggaggtcc ctgagattat ccgcgccgtc ggacagaaaa
      361 aatatctgct ggttggcctg cattccctgc gctgaaaggt gggtcatgag cctgcgttcc
      421 ggatgacagt catccttctg aacaaaaccg aagcggcggg tgtcagcagg cgcaccaacg
      481 gaaaaagact tcccggcaat aatttcaaaa ttacgctttt tgtcatcccg atcgcgaaca
      541 taaccaccat ctatacccac cacaagcggt tttcctggcc tgggcaggtt cccccagtcg
      601 cgggggcagc cggaaagaaa acctgaatga gcttcagcct cagcgtcaag acgctgcgcc
      661 acctggcata aatgattcct caccgttgag gcattcaggc tgtggcccac cggcagaata
      721 tctttcagca gacgagtcgt catttcatag gagatcatcg aggcccagcg ggtttcaata
      781 tatttcagtg ccgggtgaga ataatcgccg gcccagtcgc tgagcaaact gactgtcttt
      841 gtatcactct cttcacaacg gcaccggtac acccgaagcc cggataccgg aataacgcca
      901 aacagcgtcc ggtaccgtat tttctgtttg cctttgattc tgcgcgcagc aaggcagtga
      961 gggcaccgga tatggtgttg agtatattcg tctgcctgca gctggaccac cgactgctgg
     1021 accgtattca gcaacagctt ggattctgac accgataatc cgatgtcgtt ccgggtctcc
     1081 cctgatttct ggattgtcat cagttcctcc gttcgactgg agcctgattc atcggtgatg
     1141 actatctgga gcgtcagttg catcattgcc tcctgctgtg gtggatgact atctcccggc
     1201 tactggttgt tcatctggtg acgaagctta taatatgtgg aaacgccaag gcccgcatgg
     1261 tcgcaggcga tcctgagcct gacccctctg cttctgagtg cgtcaatttc ctggatcttt
     1321 ttgatatcgg cgccggggcg ccctgttttt tcaccccgtg cttttttcgc ggcgatgccg
     1381 tcggcctgcc tttccttcag taaggctcgt tcaaactggc tgaatgccga catcatgtgc
     1441 agctgcagtt cctgcatcgg attgtttgtg ccggcgctga acgtcagctg ctctttcaga
     1501 aaaataaggg taacgccctg gtcacgaagc cgggtggtga cagcgcacat atccgacata
     1561 ttccggcaaa ggcgatcgat ggaatgaacc agaagcgtat caccagggcg taattgcccc
     1621 aggagttcct gtaaccccgg gcggtttgtg tccttcgcgc tggcatgctc aacacaaatt
     1681 ttatcaggct gaaaacccgc ctttgacaat gcctcttcct gacgggccgt attctgatcg
     1741 gccgagctta ccctgatgta ggcatattgc acgcaaaacc tccggaaggt ctttaaacat
     1801 catagagatt taaagaataa tccataaaca ctgatttagg gaggtttata gacatttttt
     1861 cggggatctg agaggcatgc tgaaaacgta tacctttata gacatcagtc agcgacgacg
     1921 gcccagccag ataacttcag gctccagtac cggagatgca aggtcgagcc tgctcagttg
     1981 ccggttgatt ttgtggcggt tgaacctgac agcatccagg tcgtcagcaa aagggcggat
     2041 ctcgccgacc gttgtttcat catccgcatt aacgatagct tcaagaaacg ccagggtttt
     2101 atcgaactca tccgcagctg tggctccggg cataccatgg ccgcttatac aaaacggcgc
     2161 tttcagcgta gagttttcat aaatggcctc aacacgaatg tcatgaagcc agtgctcaaa
     2221 gaaattgtat tcataggtaa agcgatcgcc agcatcaaaa gcaaaatcat caatcacgac
     2281 ccggaacgga ttatcgacaa aaccgatgcc tccttcgtag gagataccgt aatctttgcc
     2341 ataaatgtga aattgatgga gatggtcgtc cccccagccc tgcactatct ggaaaatgaa
     2401 gtgaagcgcg gccagtgacg tgtcggcagc aattctcagc cgacgccaga ccatcggact
     2461 gactccatga actgctattt tgatgacgta gatcttcata gtcagcaggt attgttatga
     2521 aatgatggtg gttattttaa cccctgtaga tggcatcatt cgatggctgc cccgaggttt
     2581 ttcatgctct ctgttagttg gggtttgagg tccaacggaa cggaaacgta cgataatggt
     2641 attaacatgt tgtatttaaa atgtttttac ttggggctga cgctcagtgg aacgaaaact
     2701 tacgttaagg tttaattgtt aaaaaggatc tcttatggat cctttttagg ggctactaag
     2761 tgggttgagg gtcaatggaa gcaaaacgta cgttaaaaaa cctaactata tgattttaaa
     2821 tacataagat ttcccctatc tcacatggaa atacttttat aatttaccta ggtttgttaa
     2881 ttactattct taatatcgct aattatgacg atagttgaaa tattaaataa ctttaataaa
     2941 tatcgcactg agtaaattat taatactcaa ccggaatcat gaaataataa cccccatcct
     3001 tttaaggatt ttaaaaccgg catcctgagg aattttcata gaagaaacct tatttatttc
     3061 atgatttata tcaaggccat cagtcaatga aaagtcacag cgagataaat cacaatgcct
     3121 gaattcggta ttataaaatt ccgacccggt gaaatcagat ttacgaagat cagtttcttc
     3181 aaataaacaa tctctgaact ttgtaaataa aaaacttgat ttctgcaatc gcaaaccgac
     3241 taagtcaata aatctcattt cgcaattatc aagagaaaac gtacagggga acataatatc
     3301 agagacgttc acaccctgca gtaaacaatt tttaaactca caatcaataa gtttaaaaaa
     3361 atcgagactc aaggttttta atgagcagtt tataaacagg caattttcaa actcacaatc
     3421 gcgaaggttt atattgtcta gttgaatacg ttcaaaaata caattatagt agctagcatt
     3481 cgatattttc gcttcattca gttgtctttt tgttattttt ttaccattaa tctccatcaa
     3541 tcaaccctca gctcccataa tttctttgat aaaagccttt tctggcgtat tttcgttgtt
     3601 tacatgcatg aaattatcca tatcagtata gtgcttaata ccattcctag acaacatgta
     3661 gaatggaata caccctctgg taagttcatc aaatatatgt gttgagaaaa aaatagtttt
     3721 cccattagcg gcaatttcgt taataagatc ccacaacatc attctgtatt gaatgtcaat
     3781 accaaccgtt ggttcatcca gcaaaaagaa acgggcatcc ttacagagag ttaacatcag
     3841 ggatattata agccatcgtt tttcaccata acttaccgta taggttcttt tatgtcttat
     3901 tttttcatac cggataaaaa aatcatcatt ccacttactg ttaagttctg cccacgcctg
     3961 ctttttggtc aatttattaa aacagcaaat tagatcaaaa acctcctcat ttctaagcgt
     4021 cccggaaaga tttatcactt gaggcagact taccatttca ccaccagtga agtaacgttt
     4081 gacagaacct tcataattgt cgcttccccc ttttattatg ttaaagaggg tagttttccc
     4141 ggccccattt tcaccaagca gacctatcag tcctccctgc tttatttcaa gcgacagatt
     4201 attgaataca ggaggatggc ctttgtatga aaagctaagg gagtttattt ctaaaagtgg
     4261 taaagtcatt gagaactcca cactggttct gttttgaagg tcagcgctga aatcagactt
     4321 atgataaaca tgaggccata gactaaaata gtgatgtacg ataactcaat gcctggctgg
     4381 agaagtgtgg agtatatggc aatcggattt atgatattaa tccagtaaac tagtccatcg
     4441 ttatatttta atgatacgat ccctaaaacc atacacaccg ttatcaacac ggaatagata
     4501 gtgctggctg tctggaaagt cacacggaat gatgccataa acgtcagtga aatcatcatc
     4561 atcacattta tgcatatagt ttttaaaatt aatataaccg tctgatagtc tggccgtgcc
     4621 tggaatccaa tgaatacgac tgtaataaaa aataacacat acataactga catgataaga
     4681 gaagccatca attgagaacg aataaacaac aaacggccct ctatactgtg gacgaaggta
     4741 gcaataaaac cactttctct tctgcctgtc agatacagac agtaattaaa aagaacaaca
     4801 gaaaatgaaa tatatcctac gaaccacgat atctgatgct tcagccataa tgtatcaccg
     4861 aaatgctgtt caatttcatt gaaatgcaga aaaaagaaca acacggttgg agacataata
     4921 gtccatatta tgctaaaagg agttctgatt tgttccatta aaaaaataat cgtcattctt
     4981 aatgttgcca caatatttcc ttatggaaat ggaaccattt tagattctct ttgtttaata
     5041 ccgtttccgg cacagtatag tttattgtta aaatttagtg ctcctgaacc gttcatatga
     5101 aggaaaaaat caggacttac tatttttgca taccagacaa gatggtcgct aattctttct
     5161 ctcgcatagt aaacaaaaat attactagat attttttcta ggtagctaag taaatcatct
     5221 tctaatgtat tgttttcaag agacaatatg acatccttat gccgcagcct ggtgttttcg
     5281 cacaaatcag tgaaggactc atatttgttg catgacatga aatggcgctg atagctgtca
     5341 atgatatcct catcggtata gccaccaata aggaaattgt gcatacatat atatgattgc
     5401 catagttccg ttacagattt acacagggct tttttcagac taccggcata agataacccg
     5461 gtactatatt ttatctgact acatttattt gttgtaccat aaagcgtcag tactgcgtgt
     5521 cctggcgctc cggggagggt gatatcgaaa attctgagct caccttcagc tctgagggct
     5581 actaaaattt catctatata gttgatccct gttatgacgt ctccagaaat ttcagtgttt
     5641 gcttttccct gtaaccagta aagcagtaac gactgtcttt ccataaactc gcacagggca
     5701 ccgtccatag catcgtttaa attaccatga aagctacatc cgcatgtatc tctgtcaggg
     5761 taaaatttca ggtcatcagc agctgttata ttgtcgagag caataatgac cgctgggatt
     5821 tcttgtttct ccaggctaaa cagattgaag gcgcgagtag tcttgaatct gtgggtcttg
     5881 accgcatcct ctgtcagcga agaagtctga acaaacgctt ctgtaaaagc atctgcggct
     5941 ggcggatcca tcatttcgta taatgttttt tcactgccag ctacgatctc attaaaaaaa
     6001 tggcggcgtt caaagtattc acctatggct ccctgtattg acttcagtgt ttcaccagct
     6061 gcactggctg gtgtaattct ctcgtagtcc catacctgag aaaaagtggg catttttctg
     6121 ttcaactttg ggctcatgac cattgtggct ggccatgcgg acatcaggtg actgtagaca
     6181 ttaatcatcg atgacatctc caaaaaattg aacaatcagc ggtgcggcag tcctctggtc
     6241 aacattcatg gtttttgcta cgtatgaatc agtaaatccc gcccatacgc ggtttcttag
     6301 cccaatttga tctgcaacca atcccgcatt ctgatacatc gaacctgctt ccattaaggc
     6361 catcctgtaa cctctgtacc ggtacttgaa taaagctttt tcaaaaatga cgcaatagac
     6421 aagtgcaaaa tggggtctac cgagacgttc tgcatctcca ccggacaagc ttcggtaaag
     6481 ctcctgggta tcacacgcag cgaccggttc taatgcccga cttagtggca ggtagtgata
     6541 aacgttagtt ccggtctgcc agttttccgt gttttcagac aatcggcata aaaaaacctc
     6601 aactgggtac tgagcaccac ctgaagggta aggccgcctg acggaggctg gatcaggaga
     6661 actgaacgca ttaacgagca gcttttcaat agtgtgaaca gaacatctat ttctgtcgca
     6721 aaagccaatt ccggatggac atctttccct gctgaagtga agtgaggggg agatgttcac
     6781 tgctgaactg aagcccggtt tgaaaagaac ttctttattt tcaaatttat caagatgggc
     6841 cgtcggtact gctgaaacaa aagttcgttc agagaattcg ggaagggagg caaaattccc
     6901 tctaatatga aaatccttta cattatccag aacttcaggg tcagtgtaat gtgttacttc
     6961 aaccaaagag agttcatgtt tggcactgtt gcaaagttag cgatgaggca gccttttgtc
     7021 ttattcaaag gccttacatt tcaaaaactc tgcttaccag gcgcatttcg cccaggggat
     7081 caccataata aaatgctgag gcctggcctt tgcgtagtgc acgcatcacc tcaatacctt
     7141 tgatggtggc gtaagccgtc ttcatggatt taaatcccag cgtggcgccg attatccgtt
     7201 tcagtttgcc atgatcgcat tcaatcacgt tgttccggta cttaatctgt cggtgttcaa
     7261 cgtcagacgg gcaccggcct tcgcgtttga gcagagcaag cgcgggacca taggcgggcg
     7321 ctttatccgt gttgatgaat cgcgggatct gccacttctt cacgttgttg aggattttac
     7381 ccagaaaccg gtatgcagct ttgctgttac gacgggagga gagataaaaa tcgacagtgc
     7441 ggccccggct gtcgacggcc cggtacagat acgcccagcg gccattgacc ttcacgtagg
     7501 tttcatccat gtgccacggg caaagatcgg aagggttacg ccagtaccag cgcagccgtt
     7561 tttccatttc aggcgcataa cgctgaaccc agcggtaaat cgtggagtga tcgacattca
     7621 ctccgcgttc agccagcatc tcctgcagct cacggtaact gatgccgtat ttgcagtacc
     7681 agcgtacggc ccacagaatg atgtcacgct gaaaatgccg gcctttgaat gggttcatgt
     7741 gcagctccat cagcaaaagg ggatgataag tttatcacca ccgactattt gcaacagtgc
     7801 caaaccaggg atctggcccg ggcggatctt cgattacatt gaagtcttct ataaccggtc
     7861 ccggcgccac agccacctcg gcgacgtcag tccggaggcc ttcgaacagg cctcgtcgtg
     7921 aggacaggat ttgtctacag gcgtggggtc agtccaaact atagggcagg atcgtctacc
     7981 ggggcggggt cagtccatca acggctcgga agtgtctaga ttatccgtgg cgattcaccg
     8041 gggcaaacag gccgatcagg aacgacataa gaaagttctg tattaccgac aggtcaagaa
     8101 actgagcata agagaaactg ctgaagccac cagttacagt acatctcagg tctgcagggt
     8161 tcaggccctg ttcaggcctg aaaattaagc acattttctg aggctggaaa tcaactcatg
     8221 ctgacagcct gagcctgttg gcatggtaag caatgtgctc accaataaag ctggaaatga
     8281 aataatagct gtggtcgtat ccagtatgat atcggaacga cgcattgagg ttcatctcat
     8341 tgcatactct ctcaaggatt ttggtgcgca gttgctcttc ataaaaggcg tcactcagcc
     8401 cctgatcaat gaagatttct ggtaattttt caccctgtaa aatgaggctg actggatcgt
     8461 aggcttccca cgtttttctg ttttcaccca ggtaagcgct aaatgcctgt tgcccccatg
     8521 gcacctgaga aggcgatact atcggggaaa atgctgatac gctcacatat tcaccaggat
     8581 ttcgcagagc cagcaccaga gcacccagcc ctcccataga atgaccggat atagattttc
     8641 ttgccgttgc aggaaaatga ttcatgacga catccggaag ctctctgaga atatagtcat
     8701 acatcctgta atgaacattc cacggctgtt ccgtcgcgtt cagataaaaa ccggccccct
     8761 ggccaagatc gtaactgtcg gcatccggga cattattacc ccggggactg gtatccggga
     8821 caacaacgat gacgttatgc cgggctgcat aatgctgcat acctgatttg gtgatgaaat
     8881 tctgctcagt acaggtcagg cccgacaacc agtatagtac cggcagtttt tctgttactg
     8941 ctttgggagg aagatacaca ccgaaattca tttcacaatt aagggattgt gaataatgcc
     9001 ggtacacgtt ttgccagccg ccagagctgg catgctgctc aatgagttcc atcagccgtt
     9061 atctcatggt tatttcccct gaccgaagcc aggggaagta tctttaaatc cggacgtcag
     9121 ataaacgtat acgccgtgat tttgttaccc gccggatccc gcaggtaggc agcataggcc
     9181 ccgggaaggt gaccacgcgg gccaggttga ccttcatcag ctccaccggc ggcaaggccg
     9241 gcagcatgga aagcatcaac ctcttccggg gtggcagcag cgaagccgac agtcaccccg
     9301 ttagcggaag gtgcttcacc gttgcccgga cgggcaatga taaatgccgg cttttcgcgg
     9361 ccatagagta cccagccgtt gccaaacggg ccgaggttat tgataccaag cgtgcccagg
     9421 acgacatcgt aaaatgcgga ggatttctcg acatcggctg cgccaatgaa cacatgagaa
     9481 aagatgccgt caccagaaat taccggagtt gtcattttcc acttccttca gtttgagttg
     9541 attaaaattc tgatgggatc agtaatgaat cactgtccgg atagatttgc cttcatgcat
     9601 aagctcgaag gcgtcattga tttcatccag tgtcatcgta tgggttacaa atggctcaag
     9661 gtcaatatcc cccttcatgg catcctcgac cataccgggg agctgagtgc ggccttttac
     9721 tccgccaaac gcggaacctt tccatacgcg cccggtgacc agctggaaag gacgggtgga
     9781 aatctcctgt ccggcccctg cgacaccaat gacaacggac tgcccccacc cacggtgagc
     9841 actttccagc gctgcacgca tgacgttaac gttaccgata cattcaaagg tatggtcaat
     9901 accccacttg ttgatatcca gcagaacatc tttaatcggt ttgtcataat cattcgggtt
     9961 aatgcagtca gtggccccga actgacgggc caggtcaaat tttgtcggat tagtatcgat
    10021 agcgataata cgtcccgctt ttgcctgacg ggccccctgt accgcagcca gaccaattgc
    10081 ccccagacca aaaatggcaa ctgaatcgcc cggctgcact ttagccgtgt tatggacggc
    10141 gccaataccg gtagtcacgc cacaacccaa caggcagacg tgttcatggt tcgcctccgg
    10201 gttaattttt gccagagaaa cctcggccac aacggtgtat tcactgaatg tggaacatcc
    10261 catgtagtgg taaagaggct gaccgttgta tgaaaagcga gtggtcccgt caggcatcag
    10321 tcctttgccc tgagtctcgc gaaccgatac acagaggttc gttttaccgg actggcagaa
    10381 ttcacactcc ccgcattcag cggtgtagag cggaataaca tggtcacccg gcttcacact
    10441 ggtgacgcct tcaccaactt caacgacgat accggctccc tcgtggccga gaaccaccgg
    10501 gaaaacgccc tcagggtcat tccctgagag ggtaaaggca tcggtatggc agacacctgt
    10561 gtgggtgttt ttaatcagca cctcgccttt tttaggcgga gcaacatcaa tttcaacaat
    10621 ctccaggggc ttccctggtg caaatgcaac agcggcacgt gatttcatac gtaatatatc
    10681 ctcaatgtaa taatggcctc acctatttaa gataggcacg aaccagctca atcgtatcgt
    10741 caactgattt actgacttca tgactgtagc tgtcattctg gtcaaaggtt tcccgtatgt
    10801 ggctctccag cacctctgcc atcagtccgt tagcggcgcc ccggacggcg gcgatttgct
    10861 ggagaacgga acggcattca gcgccacttt caagtgctct ttccagagca tcaatctgac
    10921 cccggatacg gcgaacccgg gttaggacct tttttttctc ttcaggagta ctgggcattg
    10981 cttacctcac tgctctgtat ttcttatact ataggggagt attacattaa gatcaacaca
    11041 taccccacta tagtataata aatatatcag agcaccggta atgactccaa cttactgata
    11101 gtgttttatg ttcagataat gcccgatgac tttgtcatgc agctccaccg attttgagaa
    11161 cgacagtgac ttcctgccca gccttgcc
//
