LOCUS       NZ_CP089323.1           7898 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP089323.1 Enterococcus faecium strain NMVRE-001 plasmid p4,
            complete sequence.
ACCESSION   NZ_CP089323
VERSION     NZ_CP089323.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-06-07 19:48:25
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 7898
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..804)
                     /locus_tag="ctg1_1"
                     /transl_table=11
                     /translation="MCCGNSILQKGLPFFYLHKIFYTLHVENIGLSEILYVQGNSNKLI
                     PVLKKYGTPTISNINQSDTFQINTNIVLVICYLSIFIVITTIIFAFSKMKEITLKKMLG
                     YNSFDTIKDSIKELNLLFCSLIITFILSIFLSIYYSNENFFLSFLLCSIFHFIISFLFI
                     IVTLSIYHLSSIKNYLKNSRPLKLNLCILNICLFLSMILLLIASTKVINIHNEAENNSL
                     KYWERTTNLYKTNITNQLNRNNTVEENNYLKKASKFVYKIQKNYKT"
     protocluster    1..7898
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2523:2898]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2524..2898
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..7898
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..7898
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             827..2005
                     /gene_functions="other (smcogs) SMCOG1130:transposase
                     (Score: 389.3; E-value: 2.5e-118)"
                     /gene_kind="other"
                     /locus_tag="ctg1_2"
                     /transl_table=11
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDYE
                     KYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDTLEETV
                     IHLFRKGITMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKVRTLNDKYVAIFMD
                     ATYIPLKRQTVSKEAIYIAIGIREDGTKEVLSYAIAPTESTYVWNELLQDIYSRGVHDV
                     LLFITDGLKGMKDTIHQIYPKAKYQHCCVHVSRNIAHKVRVKDRKEICDDFKAVYQASS
                     KEEANTFLGSMIEKWQKTYPKVTQSLIKNQDLLTFYEFPPGIRRSIYSTNLIESFNKQI
                     KKYSRRKEQFQNEESLERFLVSIFDTYNQKFLNRSHKGFQQVTDTLASMFTE"
     CDS             complement(2030..2470)
                     /locus_tag="ctg1_3"
                     /transl_table=11
                     /translation="MLKKINAVLSLFVCITILFFSTNVINGIKTSEALYKNTAEIHMQY
                     KDDMDFNSYINALYEISTQENINISQYSFTAVNQLTILATNPNANKHWKFSKKNILARN
                     DSKVHYTNNKNSKYQLKLPNNFLNINIYPFSHVEGASIILCK"
     CDS             complement(2524..2898)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Lactococcin_972"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_4"
                     /sec_met_domain="Lactococcin_972 (E-value: 2.2e-09,
                     bitscore: 28.1, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKFLCLSALMGVLLTSGGIVSATEALNLDVPEDHTAIYGGGMEA
                     TEEGFSSSKLRYAAGGGDFNCGVNGFKVYANYYHARAKHSATAKNGRGGQVRSVQKAGV
                     RAYATCNATLTGNTGWWNVY"
     CDS             3031..3492
                     /gene_functions="other (smcogs) SMCOG1148:hypothetical
                     protein (Score: 60.7; E-value: 3.7e-18)"
                     /gene_kind="other"
                     /locus_tag="ctg1_5"
                     /transl_table=11
                     /translation="MEDLGSKLRELRVKKGYTQEYVARKFNVTRQTISKWENNKTTPDI
                     ETLKKICEFYSTNINSILNEDNLKNKQNNLLVLTAIIFNIFVTILGLFELIQMNFFSFT
                     HGIFTWFALSGLIVIDILNYFYIYYSYLKNEKFFYTIFFPLVILIILLS"
     CDS             complement(3804..3974)
                     /locus_tag="ctg1_6"
                     /transl_table=11
                     /translation="MTRKNLLFGSILLGILGFSPMLLSVINKGNKHGELKLNPNYYNSP
                     NEELFVKETDK"
     CDS             complement(3990..4529)
                     /locus_tag="ctg1_7"
                     /transl_table=11
                     /translation="MQPKETFTIKELSELFEISRQAISKHVDKLDPSLLAKNERGYKVV
                     LRSGVLQLASNLGNQRLLYRLHEYEQENDKNVYISSKNVIVNELLDKLREENEFLREQL
                     SLKEQNNSNMQKLLDQQQQLTLQANQQIEKLQEQLQLAYTEETPEDESTTILSEETESI
                     EKHTKKKKQKWWQLWK"
     CDS             complement(4557..5294)
                     /locus_tag="ctg1_8"
                     /transl_table=11
                     /translation="MSNDIVRYNNGLNSVPLRKFTPIDMDLFWGICSKMKRKGTKEEIF
                     TFKQIKELIDYNINARGDRFANDLIKMSKKIITLSFIYEDEKTYEQLNLFQKFKIDKVN
                     ETLLIKVSEEFEYILNSIGTNFTRFELENMTNLKSSYVKELYRQLMAHKDRRSKKGHWF
                     VKIEDFRALLAIPESYRMRDIDKQIFAQAKKEFLNVNSTHPAIFKTFEIKKIKAYKGNK
                     IGSLQIYFEENIPSITLDNWLEK"
     CDS             complement(6146..6835)
                     /locus_tag="ctg1_9"
                     /transl_table=11
                     /translation="MAFYLPYLLIFVSISGSIWLIYKIFQTRYSLKGSKIRFKRFFFLG
                     CIFSLIIVSSGLFGVLEGNKRVSRSILLGNVTQKYESARDKKKKEQALAQKMEEFTTCY
                     EEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYVKDTKIEEA
                     CSDLFGDTNPWFASEEEKKEKQQSVTYERYEILLQQATNMQNPTKKETALNYLKSVKEW
                     LDQQQQN"
     CDS             complement(6837..7127)
                     /locus_tag="ctg1_10"
                     /transl_table=11
                     /translation="MNNTLKEEQTTNKNYRSKTLKDIENEIKKQRAFLVPYTQERIQTT
                     IDLQVKKLHQELLDQRNKEQKKVLIQRSLDFLAPLCCLVLTLFAFWLVWGG"
ORIGIN
        1 agttttataa ttcttctgta ttttataaac aaatttacta gcttttttca agtagttatt
       61 ttcttctacg gtgttgtttc tatttaattg attagtaata tttgttttat ataaattagt
      121 agttctttcc caatatttaa gagaattatt ttcggcttca ttatggatat ttattacttt
      181 tgtagaagct attaacagaa ggatcatgct taagaataga cagatattta atatacaaag
      241 atttaactta agtggtcgtg aattttttag ataatttttt atactagata aatgatagat
      301 acttagagta actatgataa ataaaaaact aattataaaa tgaaaaatac tacatagaag
      361 aaatgatagg aaaaaatttt cgttactgta atatatgctc aaaaaaatag ataaaatgaa
      421 agttataatc aaagaacaaa ataagaggtt taactcttta atagaatctt ttatagtatc
      481 aaaagagtta tagcctaaca ttttttttag agtgatttct ttcatttttg aaaaagcaaa
      541 tataattgta gtaattacaa taaatatact aagatagcag ataacaagaa caatattagt
      601 attaatttga aaagtatctg attgattgat attggaaata gtaggtgttc catatttttt
      661 cagtacagga attaatttgt ttgagtttcc ttgtacatat aatatttcac ttaatccaat
      721 attttccaca tggagagtgt aaaatatttt gtgtaaatag aaaaaaggaa gtcccttctg
      781 tagaatagag ttaccacaac acattcacag aaaagaggac ttccatatga acgattttac
      841 tacagaaatt ctaaagactc tagcgaacaa aggcgatttg aatgaattat tccgtgtcca
      901 tttggaaaaa gctgtcaata cgcttctcaa aacggagtta acggctttcc tcgattacga
      961 aaagtacgat cgcattggtt ttaacacggg taattctcgt aacggctcct atgaccgtac
     1021 ggtcaagacc gagtacgggg aacttcatct ccagattccg cgcgaccgca acggcgagtt
     1081 caagcaacag actgttcctg cttatagacg gacgaatgat accttagagg agaccgtcat
     1141 tcacctcttc cgaaaaggta ttaccatgtc ggaaatcgca gacttgattg agaaaatgta
     1201 tgggcatcac tacacgcccc aaaccatgtc caacatgact aaagtgctga ctgaagaagt
     1261 aaatgcattt aaagttagaa ctctaaatga taagtatgtc gctattttca tggatgctac
     1321 ttatattcct ttaaaacggc aaaccgtctc caaagaagca atctatattg ccattggtat
     1381 acgagaagac ggcactaaag aagtactaag ttatgcgatt gccccgactg aatcgaccta
     1441 cgtttggaat gagttgttac aggacattta ctccagaggg gttcatgatg tcttactgtt
     1501 tattaccgat ggcttaaaag gcatgaaaga tacgattcac cagatttatc ctaaagctaa
     1561 ataccaacat tgctgtgttc acgtttcccg taatattgct cataaagtac gtgtcaaaga
     1621 tcgaaaagaa atctgtgatg attttaaggc tgtttatcaa gctagctcaa aggaagaggc
     1681 aaataccttt ttagggagta tgattgagaa gtggcagaaa acttatccta aagtgacgca
     1741 gtcactgata aaaaatcaag atttattgac tttttatgag tttccgcctg gtatccgccg
     1801 aagcatttac tcaactaatt taatcgaatc tttcaataaa caaatcaaga aatacagccg
     1861 cagaaaagag cagtttcaaa atgaagaatc actagagcgt ttcctagtat ccatctttga
     1921 tacatacaat caaaaattct taaatagaag ccataaaggc ttccaacaag tgacggatac
     1981 attagcttca atgtttactg agtaacccat tattttgcag aaggacgagt tatttacaca
     2041 aaattattga cgctccctcc acatgagaaa aaggataaat atttatattt aaaaaattat
     2101 ttggaagttt taattggtac ttagaatttt tgttattagt ataatggact ttagaatcgt
     2161 ttcttgctaa tatatttttt ttagaaaatt tccagtgttt gttagcgtta gggtttgtag
     2221 caagaatagt tagttggtta acagcagtaa aactatattg agaaatatta atattttctt
     2281 gtgtagatat ttcatacaaa gcgtttatat aactgttaaa gtccatatca tctttatatt
     2341 gcatatgaat ttcagcggta tttttatata gcgcttcaga agtctttata ccatttataa
     2401 cattagtaga aaagaatagt attgtaatgc agacaaaaag tgataaaaca gcgtttattt
     2461 tttttaacat attttgaatt tcctttcaaa tgtaaataaa aaagagagtt taaactctct
     2521 tttttaataa acattccacc aaccagtatt tccagtaagt gtggcattgc atgttgcata
     2581 agctcttact ccagctttct gaactgatcg tacttgaccg cctcgtccat ttttagctgt
     2641 tgcactatgt ttagctctag catggtagta atttgcataa actttaaatc cattaacccc
     2701 acagttgaaa tctccgccgc cagcagcata tctcaattta ctagaagaaa atccttcttc
     2761 tgtagcttcc attcctcctc cgtaaatggc ggtatggtct tcgggtacat ctagatttaa
     2821 agcttctgta gcactaacta ttcctccact agttaataag acacccatta aagcagaaag
     2881 acataaaaat tttttcataa cttatttctc ctatcttttt tactagaatt attttatttt
     2941 agtgtgtttt ataaaataaa gaactttttt ggcgcgttag tatttttatg ataaaatttt
     3001 atgtaaataa tcgtttacat aggagaaaaa atggaggatt taggatctaa gctaagagaa
     3061 ttaagagtga aaaaagggta tactcaagaa tatgtggcaa gaaaatttaa tgttacacgt
     3121 caaactattt caaagtggga aaataacaaa acaacaccag atatagagac actaaaaaaa
     3181 atttgtgaat tttatagtac taacataaat tctattttaa atgaagataa tttaaaaaat
     3241 aaacaaaata atttactggt attgacagct attattttta atatatttgt tactatatta
     3301 ggtttatttg aattgattca aatgaatttt tttagcttta cacacggaat atttacttgg
     3361 tttgctctat ctggattaat agtaatagat atcttaaatt atttttatat ttactattct
     3421 tatttaaaaa atgaaaaatt tttttataca atattttttc ccctagtgat tttgattatt
     3481 ttattaagct aatatgaagt agttagttat ttaattgcat agttgacata atgtacacta
     3541 tgccaagtag cctctctacc aagggataca ggggctcact ttgtgatttt tcattggtct
     3601 aggtcaaaag ctctttttaa ggcttgattt tctgcagttg cttctttccg tttctttgtg
     3661 aatttttacc agtcattttt tactggattg ttatttttta taaaatatga taaaattttg
     3721 gtagcgcttt ataagcgcgt gctttttcaa gaataaacac tcattatttt ttaactggct
     3781 gctcggaaga gcagtctttt ttattattta tccgtctctt ttacaaacaa ttcttcgtta
     3841 ggactgttgt aataatttgg attcaatttc aattcaccat gtttattccc tttattgatt
     3901 actgacaata acatcggact gaagcctaga attcctagta aaatagaacc gaatagaaga
     3961 ttttttcttg tcatgaatgt tccctccagt tatttccaaa gttgccacca tttttgcttc
     4021 ttcttttttg tgtgtttttc tatcgattct gtttcttcag aaagaatagt agttgattca
     4081 tcttctggag tttcttccgt ataagctaat tgtaactgtt cttgcagttt ttcgatctgt
     4141 tgatttgcct gtagggtgag ctgttgttgc tggtcgagta atttttgcat attagaatta
     4201 ttttgctctt tgagggaaag ttgttctcgt aaaaattcat tttcttcacg caacttatct
     4261 agcaactcgt ttacaatcac gtttttgctt gatatataaa cgtttttatc gttttcttgt
     4321 tcatactcat gcaacctata tagtaacctt tggttaccta agttgctagc aagttgcaat
     4381 actccagaac gtaatacaac cttataacca cgctcatttt tagctaataa ggacgggtct
     4441 aatttatcaa catgtttaga gattgcttgc ctacttattt caaataattc agataattcc
     4501 tttattgtaa aggtttcttt gggttgcatg ataattgcct cctaaattgt taggtattat
     4561 ttctctaacc aattatctaa ggtaattgaa ggtatatttt cttcaaaata aatttgcaga
     4621 gatcctatct tatttccttt gtaggcttta atttttttga tttcaaaagt tttaaaaata
     4681 gcagggtgag ttgaattaac gtttaaaaat tcttttttcg cttgggcaaa aatttgttta
     4741 tcaatatctc tcatgcgata actttctggt attgctaata gagctctaaa atcttctatt
     4801 tttacaaacc agtgaccttt tttagatctt ctgtctttat gagccataag ttggcgatat
     4861 aactctttaa cgtagctact ctttaagttt gtcatatttt ctaattcgaa acgagtaaaa
     4921 ttagttccga ttgaattaag tatatattca aattcttcag aaacctttat taataatgtt
     4981 tcattcactt tatcgatttt aaatttttga aacagattta attgttcata tgttttttcg
     5041 tcttcataaa taaaagacaa agtaatgatt ttttttgaca tttttattaa atcattagca
     5101 aaacggtcgc cacgtgcatt tatattgtaa tcaattaatt cttttatttg tttaaatgta
     5161 aaaatttctt cttttgtacc ttttcttttc attttagaac atattcccca aaataaatcc
     5221 atatctatag gggtaaattt tcttaaaggg acagaattta atccattatt atatcgaact
     5281 atatcgttac tcaataaaaa tcacctcaat aaattatgtt atcatagaca taagaggatg
     5341 taaaacacaa tttatccccc atagtgtgac aatttatccc ccatagtgtg acaatttatc
     5401 ccccatagtg tgacaattta tcccccatag tgtgacaatt tatcccccac tacctatgtc
     5461 aatacttact ctcccataag gttgctaatc cctaacagtt attattaaca gtatatctaa
     5521 cagtatatct aacagtatat cttaagagca cattgaattt cccgcctaaa aaactcctac
     5581 tttttcctcc aaaaaggttc gcgaattttt ctaaactgga aaacttgctc cctacggtcg
     5641 ctaaaaaggt gtgatcgcta tgctctcata ttatactgcg cagtcgcctc cggctccttt
     5701 gctaaaaccg ttgttcaaag aggaggtgtg agactctgaa agcttgtcta agccgttcta
     5761 agacaattct tgattaattt cccttaatct agtcgagaag cgccttacag gcggtcaggg
     5821 caagccctaa caaccctaaa acaagtgata cttaaaaaca ccacacaaat ttaatttttt
     5881 aagatataat aacttgtcgc ctatccgaca gtcttgcgac tggaaggagg tgtatctaat
     5941 gtttgaactg ttcatttgcc cccttcttgt aggagtttgt gtctctttat tcagttattg
     6001 gttgaataac cgaaacaaga agtaaaatca ataaaggcga catcaacctg aaaaaaagcc
     6061 ccagagaatc cgacctctct ggggctttcg tgtatctaat gtttgatcat ttgcacattc
     6121 agtttaacat gattttaaat caaattcaat tttgttgttg ctgatctaac cattccttga
     6181 cactttttag atagtttaag gcggtttctt tttttgtcgg attttgcatg ttagttgctt
     6241 gttgaagtaa gatttcatag cgttcatatg tgacagattg ttgtttttct tttttttctt
     6301 cttcactggc aaaccaaggg tttgtgtctc caaatagatc actacaggct tcttctatct
     6361 ttgtatcttt tacatattgc acgtcttttt tggttcgctc atagttgtct tgaacctctt
     6421 tttgctgttt ttctggcaag ttttgataaa gacgagtgag tttttccatg tttttatccg
     6481 tcaaacgttt ttcttgattc acaaaaatat cgttcatttc ctcataacaa gtggtaaact
     6541 cttccatttt ttgtgctaat gcttgctctt ttttcttttt atcacgcgct gattcatact
     6601 tttgagtgac atttcctaat aaaatacttc tagaaacgcg cttatttccc tctaaaacgc
     6661 cgaataagcc gcttgaaacg attatcaagg aaaatataca gccaagaaag aaaaatcgct
     6721 taaatcgaat tttagagcct tttaatgaat atcttgtttg aaaaatttta tagatgagcc
     6781 aaatacttcc tgaaatacta acaaaaatga gtagataggg taaataaaat gccattttag
     6841 cctccccata ctaaccaaaa tgcgaacagt gtcaggacta agcaacataa gggggcaaga
     6901 aaatccaatg atcgttgaat aagcaccttt ttctgttcct tatttcgctg gtctaatagc
     6961 tcttgatgga gttttttaac ttgtaaatca atcgtagttt gtatcctttc ttgcgtataa
     7021 ggaacgagaa aagcacgttg tttctttatt tcgttttcta tgtcttttaa cgttttagag
     7081 cgataattct tgttggtggt ctgttcctct ttcaacgtgt tgttcatggt ttcttcgagc
     7141 cggtctaatt tccggttgtt caggcgtaag agttcgttgt tctcttcgta cttcttctgc
     7201 agtttcgcga atgctagctc gagctcttcg tagctcgttg gttcgctgtt ggttataggt
     7261 tcgttctcgt ctgtccagct catgtaaaat cgtctccttt tcgtagtcct ttcctagtct
     7321 gttggatcgt acttttttct ttttgtggat caattcgtaa gtgaaatttt tcccgcgatt
     7381 gaagcaatga atccccaatg ttttgaggga attacaaaat tggtcatagg ttctggtttt
     7441 tttgtttttc attgtttgat cgatcgcaat ccgaatttcg tctttccaaa caggttcatt
     7501 tttttctttt aattttattt cagacatggt tcgtttttct ggtttctttc ctcgctcagt
     7561 gattggtaag ttatgtgcaa gacaaatctc gtcatttagg tcataacatt tgtttagaaa
     7621 tgcttgacca tgagcttgaa atttttttcc agtctccaga ttaacggagt taatgacaat
     7681 gtgattatga atatggtctt tgtctgtatg tgtgtaaata gctgtttggt gatcgggggc
     7741 tatttttttt gcatactctg cccctagttg attagctttt tcagcggtaa tttctcctgg
     7801 tcgaaaagat tgaatcaata agtgtgcctg tacacggtcg tcttttccat acagcatgcg
     7861 aatttgtttc atttcacttt tggcataatc gacgtcac
//
