LOCUS       NZ_CP083145.1          21380 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP083145.1 Bacillus thuringiensis strain GC-91 plasmid pCH_186-a,
            complete sequence.
ACCESSION   NZ_CP083145
VERSION     NZ_CP083145.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-06-07 23:46:00
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 229300
            Orig. end    :: 250680
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21380
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11380]"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11380
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     cand_cluster    1..21380
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="single"
                     /product="sactipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21380
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="sactipeptide"
                     /region_number="1"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /tool="antismash"
     CDS             complement(471..884)
                     /locus_tag="ctg1_217"
                     /transl_table=11
                     /translation="MREIAKKVKMIRLQEEHSGLKADAEQYSSKRCKIERESINLEKNR
                     VKKRTQKFQTSEEKWDIKCKKAVQLFNQGEEYPTIAKKLRCNVSSLYRELKKRGTLQTP
                     KQVAVSKSLKSPITSTRAKKTNFERYKEYYMYK"
     CDS             complement(1431..1724)
                     /gene_functions="regulatory (smcogs) SMCOG1058:ArsR family
                     transcriptional regulator (Score: 77.5; E-value: 9.6e-24)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_218"
                     /transl_table=11
                     /translation="MTTMQVSNEMYKIPEADIELLKIMAHPVRLQIVKELEHHKICNVT
                     QLTELLDVPQSTVSQHLSKMRGKILRSERRGLEMYYHIVNSKACQIVGVLGI"
     CDS             complement(1784..2116)
                     /locus_tag="ctg1_219"
                     /transl_table=11
                     /translation="MICAGTKEWPCMGVGIYRKDSHVSTYAFPFACIGLMLSVYQITIQ
                     AFPNSEMQICSVGVSCTKDYLNLFGFISIPMLSFVGFLAIIILLYIKSERDKRINNTAI
                     MNNMLE"
     CDS             complement(2337..2549)
                     /locus_tag="ctg1_220"
                     /transl_table=11
                     /translation="MSQVPGFLKFVLAKERRYVYLVVAEKKNKKVHTHMVYRFGSLEKA
                     LETMYEMRGDFENLFPLELKERGYD"
     CDS             complement(2622..2825)
                     /locus_tag="ctg1_221"
                     /transl_table=11
                     /translation="MNENKRNMLLSFINSILFIFASLLPFSNNEYVYVISKIGAAAGVI
                     NIVMMSVFLYFQSKKTGHLLNW"
     CDS             complement(2877..3473)
                     /locus_tag="ctg1_222"
                     /transl_table=11
                     /translation="MPACSNSTQTKNDSRPAQAVQNGIQQHVEGKGIVDIPGDYKGKLK
                     DLETVKGKVLYIKDGDTIDVNVKGQKQMVRLLLLDPPESVSQKIPPQKMGKEPSSFLKK
                     QLEGKSVTFVYDRGPKEDKYGRKLAYVFCVGIHINELMVKSGYGIIAYISRPNTTFLSE
                     MKEAENEAKESKVGVWSIKGFVDEKNQHYNRKDAT"
     CDS             complement(3950..4066)
                     /locus_tag="ctg1_223"
                     /transl_table=11
                     /translation="MTNTISSFENRNNGEKLDAKLSYVIQKQRIMFIHEKKK"
     CDS             4269..5126
                     /locus_tag="ctg1_224"
                     /transl_table=11
                     /translation="MDILLAILPALFWGSIVLFNVKLGGGPYSQILGTTLGALVFSIGV
                     YIFIKPVLTPVMIIVGIISGLFWALGQANQLKSIDLIGVSKTMPISTGMQLVSTTLFGV
                     IVFHEWSTTTSVVLGVLALLCIIIGIVLTSLQSKEEKNDEQKGNFKKGIVMLLISTLGY
                     LVYVVIIRLFGIDGWSALLPQAIGMVLGGILLTFKHQPFNKYAIHNIIPGLIWAAGNMF
                     LFISQPRVGVATSFSLSQMGIVISTLGGIFILGEKKTKRQFIAIVIGIIFIIAAGIMLG
                     IAKG"
     CDS             5143..5928
                     /NRPS_PKS="Domain: PKS_KR (8-120). E-value: 2.9e-10. Score:
                     32.2. Matches aSDomain: nrpspksdomains_ctg1_225_PKS_KR.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     224.1; E-value: 3.3e-68)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_225"
                     /sec_met_domain="adh_short (E-value: 1.2e-35, bitscore:
                     117.6, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYTDLKGKVVVITGASTGLGRAMAIRFGEEQAKVVINYYSNESEA
                     NEVVQVVKQAGGEAIAVKGDVTVESDVINLVKSAVKEFGTLDVMINNAGIENSVPSHEM
                     PLSDWNKVIATNLTGAFLGSREAIKYFVEHDIKGSVINMSSVHEQIPWPLFVHYAASKG
                     GVKLMTETLALEYAPKGIRVNNIGPGAMNTPINAEKFADPEKRADVESMVPMGYIGEPK
                     EIAAVAAWLASSQASYVTGITLFADGGMSLYPSFQAGRG"
     aSDomain        5167..5502
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_225_PKS_KR.1"
                     /evalue="2.90E-10"
                     /label="ctg1_225_PKS_KR.1"
                     /locus_tag="ctg1_225"
                     /protein_end="120"
                     /protein_start="8"
                     /score="32.2"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VVVITGASTGLGRAMAIRFGEEQAKVVINYYSNESEANEVVQVVK
                     QAGGEAIAVKGDVTVESDVINLVKSAVKEFGTLDVMINNAGIENSVPSHEMPLSDWNKV
                     IATNLTGA"
     CDS_motif       5170..5241
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_225_0001"
                     /evalue="5.20E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg1_225"
                     /protein_end="33"
                     /protein_start="9"
                     /score="9.5"
                     /tool="antismash"
                     /translation="VVITGASTGLGRAMAIRFGEEQAK"
     CDS             6278..6694
                     /locus_tag="ctg1_226"
                     /transl_table=11
                     /translation="MTKKLFTEREIQILSNNLYVKSVSQKGITYTEEFKHIFIEENEKG
                     KLPRNIFEECGFDIDMIGMKRVMSSGSRWRAAYRKNGVLGLRDTRIENAGRTLERELTL
                     EEKYARLEAERNLLKAENELLKKIKLMEGRMRRK"
     CDS             6760..7611
                     /gene_functions="other (smcogs) SMCOG1026:transposase
                     (Score: 205.5; E-value: 1.5e-62)"
                     /gene_kind="other"
                     /locus_tag="ctg1_227"
                     /transl_table=11
                     /translation="MVSHLCKVAGVSRSGYYNYFSVSSQEQRKQKSDRDEILKETILKA
                     LRFRNRNKGARQIKMTLAGQFQVVYNLKRIRRIMKKYEIICPVRKANPYKRMLKATKEH
                     RIVPNQLNREFKQNTPGKTLLTDITYLVYGKNQRAYLSTILDGSTNEILAYHVSEQMTL
                     ELVTTTLHKLKRNPRIRLTEGAYIHSDQGSHYTSPTYQKLVKKLNLGQSMSRRGNCWDN
                     APQESFFGHLKDEAHIKPCVSFNELKQEIKKYMTYYNHYRYQWNLKKMTPVGYRNHLLD
                     VA"
     CDS             complement(7766..8053)
                     /locus_tag="ctg1_228"
                     /transl_table=11
                     /translation="MSKMKLINFDTYRNSIVLFENNGEIISVSAHFQFFEGSESYIQGF
                     IDNEEVIHFKSNNPGPNISIYRFAPKNITKLIISSENRTNGMVTLYTSEI"
     CDS             complement(8088..9797)
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 174.8; E-value:
                     5.1e-53)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_229"
                     /transl_table=11
                     /translation="MNKKINKQDEIQISYKELLFLYPYLKNTKTLLAFGLIGMVIASLI
                     IAPIPYIIGYIIDKVILLNKSYDQLLKTTLILLLIYCINYLISIGYEYLFTRVQQNVVN
                     EIRLSMISNIIDAPLSYINQKEKGYILSRIAESGNVSALFSPNLLRVFSGIFDFFFALF
                     IMFNLSVKLTGIIVIIIPIYFIISKHSSKMISKSTTNVYESSAVLNAEMYETLNGIEDI
                     KLLNGKNIQTNKIKSKLNNVIKSALKQNLHFIFFMQNLIVTNNFVTVIVLLVSGILILQ
                     NQLTIGVYTSFSIYMAKLLATTQALGSLDITLKPVCISIKRIKEFFNLDVENTLGTNIM
                     KEPINSIEFKDVCFKYNGNSDLIFDHLNVQIEKGDKLLIDGINGSGKSTFIKLLTGLYQ
                     PESGKILINNIDYNLIHKESVRDRIGIVSQNIFLFKGTILDNILYGQTNKTKEDVVKLM
                     KRYHLTSHLNRFENGLDTIIVQDGSSVSGGQAQFIAFLRAILTKRDIIILDEAASNLHI
                     DTRNLMYEILQNYNLCNILIMISHQQDGLYFLNKTLELTHGNKRIALNGSML"
     CDS             complement(10001..11380)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thurincin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_230"
                     /sec_met_domain="Thurincin_rSAM_RRE (E-value: 1.3e-34,
                     bitscore: 112.7, seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.6e-08, bitscore: 29.3,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 1.2e-07, bitscore:
                     26.0, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="subtilosin (E-value: 2.8e-46, bitscore:
                     152.2, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 4e-21, bitscore: 70.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 2.2e-09, bitscore:
                     32.1, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 2.7e-08, bitscore: 28.7,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNGYLFWKEKLEIRKFTSNYESMLVVHKNPNESAPTLKNENTFTI
                     NKTATEIIELIDGTKTYGQVVSFLSLKYSEDPISIEKKLNAFLNNVSKVYNMNIGTQEE
                     PINVPVNLIEEQTIYPKVASIEITNRCNVRCRHCYGDFGAVKPKVMSLDQIKSLLDDLN
                     NIGVKLIELTGGDITVHPNLKEILLYALNLDFSQITLLTNGIALSEKVMDIIIKNKSKT
                     FVQIDMHSLDDNYLTWFFKVPNTLHKIKNNIMKLAENDVRLRIATIVTHLNVHEVEDIA
                     EWVHNLGIDSIGVSPVIPMGRALGCSDLYLNEEDVKTYGEALLKINKKYPKFVSLYEGA
                     RAEIRNCGAITSHIVIAPDGEIKMCTMHSLDDLKNSIGNVFEQNIKDIYDEKFKYINAF
                     FNLQAPQMDSEECKECENKRFCSTCFLRSFIKAQEIGDKCKWFKNHVPEIIKEPLMVGQ
                     N"
     CDS             complement(11382..11492)
                     /locus_tag="ctg1_231"
                     /transl_table=11
                     /translation="MTNSYVKNKSYIFIENEYGIFVIHKLKTNLNFIGDD"
     CDS             complement(11545..11667)
                     /gene_functions="biosynthetic-additional (sactipeptides)
                     predicted sactipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_232"
                     /transl_table=11
                     /translation="METPVVQPRDWTCWSCLVCAACSVELLNLVTAATGASTAS"
     CDS_motif       complement(11638..11667)
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: METPVVQPRD"
                     /locus_tag="ctg1_232_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       complement(11545..11637)
                     /prepeptide="core"
                     /locus_tag="ctg1_232_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="28.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="WTCWSCLVCAACSVELLNLVTAATGASTAS"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="METPVVQPRD"
                     /leader_location="[11637:11667](-)"
     CDS             complement(11773..11895)
                     /gene_functions="biosynthetic-additional (sactipeptides)
                     predicted sactipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_233"
                     /transl_table=11
                     /translation="METPVVQPRDWTCWSCLVCAACSVELLNLVTAATGASTAS"
     CDS_motif       complement(11866..11895)
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: METPVVQPRD"
                     /locus_tag="ctg1_233_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       complement(11773..11865)
                     /prepeptide="core"
                     /locus_tag="ctg1_233_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="28.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="WTCWSCLVCAACSVELLNLVTAATGASTAS"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="METPVVQPRD"
                     /leader_location="[11865:11895](-)"
     CDS             12444..12827
                     /gene_functions="regulatory (smcogs) SMCOG1136:GntR family
                     transcriptional regulator (Score: 71.9; E-value: 1e-21)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_234"
                     /transl_table=11
                     /translation="MKIVLSNVSSLPLYQQIKEQIKESIFNNELKEGEQLPSIRSLAND
                     LHVSVLTTKRVYAELETEGFIITKVGKGTYVAPTNLELLMESKRRMVEVKLTEVCQMAR
                     SIGIHADDLHSILDLILEEENEK"
     CDS             12824..13690
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 147.6; E-value:
                     7.9e-45)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_235"
                     /transl_table=11
                     /translation="MNVVLEVNNLNKSYGNFSLKDVTFSLNTDCITGFIGTNGSGKTTT
                     IKAILGLILKDTGKINFLGKDMDKHERKSKNKIGIVLDEGYFYDELTVKEMKNVIAPSY
                     TEWDETVFQNYIKKFNLNLEQKISTLSKGMRMKFAVALALSHHADLLIMDEPTSGLDPL
                     VRSELMDILLDFMKEPGKSVFFSTHITSDLDKIADMIILIDDGKVLVNDEKDVLIDTHA
                     LVKGDNRLINKQTRPLFLNLHQTHYGFEGITNKKDDVRRLMPDVLIERPTIEEIMLSYI
                     GGNIHVN"
     CDS             13680..14327
                     /locus_tag="ctg1_236"
                     /transl_table=11
                     /translation="MLINLVMKDFLLVKKYFLILLVFAAIAPIYLSSQLQLNDGGLVSF
                     LLTVILMEYILFGTVSKFEDQYKGAALLCATPYTRSAFVKAKYLFLFVIFICAAIIRII
                     ISVVAPSGIESLSASALGITFLTLSILFGVLLPVQFKFGYDKTKIISLLTAFLIPFVAP
                     TLIRGLQSSDIDFKSIFPFSPTVLTWMPCFISIIIGFISMIISLKVYAKKDL"
     CDS             14548..15825
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075:alkaline serine protease, subtilase family
                     (Score: 252.8; E-value: 1.4e-76)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_237"
                     /sec_met_domain="Peptidase_S8 (E-value: 2.8e-42, bitscore:
                     139.5, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIIKFLLLINLISGTFIPITTVHAENKSQYYTIMLKNYENNQK
                     LASKFQKYDMQVVYSVPEIGVIQVKATEKAMNIVHSDPNIDSYNKSLQSFNSREVATNV
                     SSPLPLNEIWENQWDMQQVTHNGDSYRLYPGTKNVTVGIIDSGIDINHPDLKDNISPGS
                     KNLVPKGGFREQESQETGELNRLIDLRGHGTFTAGQVAANGFMKGVAPGIGIKMYRVFG
                     NGAGEAIWVIKAIVEAAKDNVDVINLSLGEYLINGIVSSSDGESSEELSEIKAYRKAIK
                     YAKSKGSIIVAAAGNDALDVTNKQEMNDFFRKKNENTGVTFTGEVLDVPAELPNIVTVS
                     SVGPSKLLSLFSNYGESFIDIAAPGGDNRLFQQYGLEQWVKNKLMLKELILTTAPGGGY
                     ALSIGVSLAAPKVSGALALIIDKNNF"
     CDS             15875..16057
                     /locus_tag="ctg1_238"
                     /transl_table=11
                     /translation="MIPLLIKVFLVMVCLMSIKRFPNKIYTLQFGFKLTIDSDFLMEPL
                     FKASLIALNKGFLLY"
     CDS             16405..16563
                     /locus_tag="ctg1_239"
                     /transl_table=11
                     /translation="MQDRKKAIKSTGSVMKPDFAETDAQKVKQEIQNDVRAGQGAMTSR
                     EAGAMRD"
     CDS             complement(16721..17464)
                     /locus_tag="ctg1_240"
                     /transl_table=11
                     /translation="MKEVLDVETYLKKMKNQKINYDKVLRKMINDWEARNERPKVLLHS
                     CCAPCSTASLEFLAEHADITVFFSNSNIHPKSEYMRRSNEQKIFVEKFNDRTGHTVGFL
                     EDDYRSNVFFKMVKEEGLAEEPEGGLRCSACFDMRLDRSAEVAQEKGFDYFGSAITLSK
                     NKNSQLINELGIGVQKNYDSRYLPSDFKKSNGYQRSIEMCNEYDVFRQCYCGCSFAAEK
                     QGIDLRSVNKDAIHYLKENNLSLKK"
     CDS             complement(17624..17737)
                     /locus_tag="ctg1_241"
                     /transl_table=11
                     /translation="MLYIIGFLVIIVVVIRLNVKYYQLKGNPKDFVMKKKD"
     CDS             complement(17756..18394)
                     /locus_tag="ctg1_242"
                     /transl_table=11
                     /translation="MKVLIFELILIVLLIPINIMVKKHAPKWKGRAGEKMVKRILRKLD
                     HERYWVLHDVTVHTEYGDTTQIDHIVIAETGIFVIETKNYEGWIYGSEKAARWTQGIFR
                     KKHSFQNPFRQNYKHMKTIEWVMEQQLPCISIAAFHPKCSLKRVNVHSKDKYVLYYNDL
                     KKCIESYIDVKLTKDEVEHIYQTILQANITDKDTENKHVKYLQNKFAKQ"
     CDS             complement(18411..18947)
                     /locus_tag="ctg1_243"
                     /transl_table=11
                     /translation="MIAICRMNRTCSRAGMPAKQTRKIETKIIFKLEIHTSYLIITQFI
                     LIGVLVLKRNREYTALRNSILIGWLLTIIVMGLSIYFSSIIYLLIGCFILSLKYGLMGT
                     IKNVEKRLPTWANFGVIEKPVNRRVTRPFQFRGGLIVSLALGFIEMVIKGLCISYYILG
                     LETHVYRLMHRNTRM"
     CDS             complement(19257..19874)
                     /locus_tag="ctg1_244"
                     /transl_table=11
                     /translation="MIGVLCIFVFMIVVLIPLHTAHASVKVDFNELKGNDVSSSFKEGL
                     NNRKKATGKDDSFGSSIIQKIEGMYAPAFKVGVNIFSISFILGVIVMVMALITKNGQWM
                     KWATGSMIFSFVSMMAMRLSVYFLFSSDVFSFMNIFTDFLNLFKSTALIFTPFMLIAGI
                     RLRKIHESTKQPEYYRWSNRVITGSCFLCMLAVLAPWLFANM"
     CDS             complement(19889..20521)
                     /locus_tag="ctg1_245"
                     /transl_table=11
                     /translation="MIIDHISNNVVKKLEQTVRYEKKQVQVLRVSKSSSNMHAYMIFPE
                     FSEVKIFNTDLDEYIEDLSTSLKYVIDRKLSLQEIEKQNHSFIMTCAVEEDGVIDDETI
                     HFNTTYVKPPTLASKVFKLVCGLGNRLNSLKELHITVLNNNINRIEIGFYNENETYVAV
                     EKEEIANAIMGAYTKANIYYSADLRYVAEGNEIKLKSVKPKLAGDVL"
ORIGIN
        1 accacagaaa gatatacatc aataaaaaga attaattata atataaaaat aaaaggaata
       61 tattgagaaa tatataataa aattgaatat tctttctttt tatcgtaaaa tcaatatgag
      121 tcaagtgaca acatctctct aactcttcta aaagaatcct ttatgacatg aggattcttt
      181 tgctttagac aaattattct tattttaaca tttgcaaaaa aactcttctt aaccaactac
      241 tcaacaaata taagtaagga tttagtttta tgaatatttt tatgatctaa gcaacaggta
      301 atagccttca atatttgtta gatgtaaaaa tatataaaaa aacccaaaag atgctctatc
      361 aatactgtaa gaagatttgc tgctaaacat gcattttttc attgtaccct ttataatctg
      421 agctttttaa cactaaagaa ttaagtatag atttatagcc atgaattctt ctatttgtac
      481 atataatatt ctttatatct ctcaaaattt gttttttttg ctcgtgttga tgttatgggt
      541 gattttaatg atttagatac tgctacctgc tttggtgttt gtaatgtgcc ccgtttctta
      601 agttctctat acaaactact cacattgcac ctcagttttt ttgcaatagt tggatattcc
      661 tctccttgat taaataattg tactgctttt ttacatttta tgtcccattt ttcttctgac
      721 gtttgaaatt tttgagttcg ttttttaact ctattttttt ctaaattaat actctctctt
      781 tctattttac atctcttgga agaatactgt tctgcatctg ccttaagccc ggaatgctcc
      841 tcctgtaaac gtatcatttt tactttcttt gcaatttctc tcaagttaaa gtcacctcat
      901 tttgtttgat aaattctacc agtacttgat caccctattg tctgtatccc caatcatcgt
      961 ttataaacag ctataaatac tcacattccc cttataatag ttttcaatct aatatttacg
     1021 gaaaattata atcaattcta tttttacata attggaaact atagtaaatt gataatattg
     1081 acacagaata ttctaaacct taattcatac tatacacatc aatacactaa ttatcccctt
     1141 tgcttaaaaa gtcgaaaata tcgttttcgc atagcaaaac acggtatccc ctattcagag
     1201 tcatataaaa caaaatactt tatctattat agctatggca caaagaaaaa gaatgcagac
     1261 atgtactgca ctctttttta gtaacctcta tatcaatttt tcaccacagt cagctcctcc
     1321 attattagaa ggactaaact ttaagcttgt gaatttatca ttctgcagta catcatcttt
     1381 tgcagctata tttaacaaca ctctttctat catcctattt cgatttagaa ttaaatacct
     1441 aatactccga caatctgaca tgccttggaa ttcacaatat gataatacat ctctaatcct
     1501 cttctttctg agcgaagaat ttttccacgc attttagata aatgctgaga tacggtagat
     1561 tgaggaacat ctaatagctc tgttaactgt gttacattac aaattttgtg gtgttctagc
     1621 tccttcacaa tttgtaatct aactggatgg gccatgattt ttaatagttc tatatccgcc
     1681 tctggaattt tgtacatttc attacttact tgcattgttg tcatttttta tttctccttt
     1741 tttaatttct ttatattttt atctatttat aggtattttt tgtttattcg agcatattgt
     1801 tcataatcgc tgtattgttt attcttttgt ctctctcaga tttaatatat agaagtatta
     1861 tgatagctaa aaatccaaca aaagatagca taggtatcga aatgaaaccg aataaattta
     1921 agtaatcttt tgtgcaagaa actcctactg aacaaatctg catctcacta ttaggaaacg
     1981 cttgaattgt aatttgatat acagataaca ttaaaccgat acacgcaaat ggaaatgcat
     2041 acgtgcttac gtgcgaatct tttctatata tccctacccc catacatggc cattctttgg
     2101 taccagcaca aatcacatgg cggcagcttt atccattcac taaaaaacaa actaattaac
     2161 attgcactag tagctatcgt ccaagcaatt acaatgtgat acttttgaat gatcaacatc
     2221 ttattttcgc ttcacctatt ttttaaaata caaaacattt gctagtatat gactagttta
     2281 tttccgtgtt tcgaataccc tgtttcaata gaaagtatcc aatcattgat atcttctcag
     2341 tcgtatcccc tctcttttaa ttctagaggg aaaagatttt caaaatcacc acgcatttcg
     2401 tacatggttt ctaatgcttt ttctagcgaa ccaaatctat ataccatgtg tgtatgtact
     2461 tttttgtttt tcttttctgc tacaactaaa tatacatacc gtctttcttt cgctaaaaca
     2521 aactttaaaa atccaggtac ttgactcacc tttcacactc cttttcggct ttccttacca
     2581 aacttaaaag aatatgagta aggaaaacta tttagcttta attaccaatt taataaatgt
     2641 cccgtttttt tgctttgaaa atacaagaaa acgctcatca tcacaatatt tattacacca
     2701 gctgcagcac caattttgga gataacatac acatattcat tattactaaa tggcaataga
     2761 ctcgcgaaaa taaataaaat tgaattgata aaggataaga gcatatttct tttgttttca
     2821 ttcattcaaa aaacctccat tttgcacaaa tatttgtatt gcaatgggtt agggtgttaa
     2881 gttgcatctt tacggttata atgctggttc ttttcatcta caaagccttt aatgctccat
     2941 acgccaacct ttgattcttt tgcttcattt tctgcttctt tcatttcaga tagaaatgta
     3001 gtattaggtc tagaaatata ggctataatc ccataacccg acttgaccat taattcgttg
     3061 atgtgtattc caacgcaaaa tacataagcc aattttctac cgtatttgtc ttcttttggt
     3121 ccccgatcat aaacaaatgt tacacttttc ccttctagct gtttctttaa aaaggaagat
     3181 ggttcttttc ccatcttttg tggtggaatt ttttgagata cagactcagg gggatctaat
     3241 aacagtaacc ttaccatctg tttctgcccc tttacgttta cgtctattgt atctccgtct
     3301 tttatatata ataccttccc tttaacggtc tctaagtctt ttaatttccc cttataatcc
     3361 cctggaatat caacaatacc tttcccttct acgtgctgtt gtattccgtt ttgtactgct
     3421 tgggcaggtc tcgaatcatt ttttgtttgc gtcgaattgc tacatgctgg catttgaaat
     3481 acaaatgatg ttatacaaat agccttaatt catattttca tatcggaaat tcttcctcct
     3541 aatcaaaata cgtaaatagc tacatctaat aaacaaacgg actctctatt gtatttactt
     3601 ctcgataatt acaatatagg caatactgta tccattttgg ataatcatta taaagtgctc
     3661 taaatgagag tttcttacaa ttcgggcata ttgacactat gtttttttca ttctcttcct
     3721 gacttttcaa tttttcaaaa gaaacattag tagatgctat attactggta cacaatatac
     3781 atcccccttt tcagtcttga aatcttaaaa acaaataaaa aaggacacac ctatcgcata
     3841 tgtatgcgta ggtgtgtcct tttgcaagat agttttagaa gtattttgtt actttcatca
     3901 tatcatactt cttattaatt ttatatatga aattaaagat tttacgatat tatttctttt
     3961 tctcatgtat aaacataatg cgttgttttt gtataacata gcttaatttt gcatcaagtt
     4021 tttctccatt attcctattt tcaaaacttg aaattgtatt ggtcatattc tttctaataa
     4081 cttttttatt tcgtgctagt tattttcttt ttcaacatga tgttattttt cttttatttt
     4141 gggtaaacaa atattacggg tagaaaaacg aaaaatttct cttattctaa aataattccc
     4201 tcgacacaaa gatactatct cgtacaagca ttcaacttaa taaatatgtt ttaggaaggt
     4261 tagaaaaaat ggatatttta ttagcgattt taccagcatt attttgggga agtattgtac
     4321 tcttcaacgt taaactagga ggcggtcctt acagtcaaat acttggaact acccttggcg
     4381 ctctagtttt ttctatcggt gtttatattt ttataaaacc cgttttgacg cccgtgatga
     4441 taattgtcgg gattatatct ggcctatttt gggcattagg acaagccaat caattgaaaa
     4501 gtattgattt aattggggtt tctaaaacaa tgcctatttc aacagggatg caattagttt
     4561 cgactacttt atttggggtc attgtatttc atgaatggtc aacaacaaca tctgttgtat
     4621 taggtgttct ggcacttctt tgtatcataa tcggaatcgt tctaacatca ctccaaagca
     4681 aagaggagaa aaacgatgaa caaaaaggaa atttcaaaaa agggattgtg atgttattaa
     4741 tttcaactct tggttactta gtatatgtgg taattatccg cctattcggt atagacggat
     4801 ggtcagcgtt attaccacaa gccattggta tggtgttagg tggaattcta ctaaccttta
     4861 agcatcaacc atttaataaa tatgcgattc acaatattat tcctggttta atttgggcag
     4921 caggaaatat gtttttattt atttcccagc cgcgtgtagg ggtggcaaca agtttttccc
     4981 tttcccaaat ggggatcgtg atctcaactt taggtggaat ttttatatta ggtgaaaaga
     5041 aaacaaaacg acaatttatt gcgattgtca ttggaattat cttcattatt gcagctggca
     5101 ttatgttagg aattgctaaa ggataaaaag gaggaaaaaa ttatgtatac agatttaaaa
     5161 gggaaagttg ttgttattac aggtgcatcc acaggattag gaagagcgat ggcaattcgt
     5221 tttggagaag aacaagccaa agttgtaatt aattattatt caaacgaatc agaagcaaat
     5281 gaggtagtac aagtagttaa acaagcaggt ggagaagcga ttgcggtaaa aggagatgta
     5341 acagttgaat cagatgttat caatctcgtt aaatctgctg tgaaagaatt tggtacactg
     5401 gatgtcatga ttaataatgc gggtattgaa aattcagtac cttcacatga aatgccatta
     5461 agtgattgga ataaggtaat tgctacgaat ttaacagggg ctttcttagg gagccgggaa
     5521 gcaattaaat attttgttga gcatgatatt aaaggtagtg ttattaatat gtcaagcgtt
     5581 cacgagcaaa ttccatggcc attatttgta cactatgcag caagtaaagg tggcgttaag
     5641 ctaatgacag aaacattagc actagaatat gcaccaaaag gaatccgtgt aaataatatt
     5701 gggcctggtg ctatgaatac gccgattaat gctgaaaaat ttgcggatcc agaaaaacgt
     5761 gccgatgttg aaagtatggt tcctatggga tatatcggag aaccgaaaga aattgcagcg
     5821 gtagcagcat ggcttgcttc ttcacaagcg agctatgtaa caggtattac actgtttgct
     5881 gatggtggta tgtcgctata tccatctttc caagctggac gtggttgatt gatatataac
     5941 taaattagtt actttcaata agtttaaatg cggcagtaag ctttttattg aataaccttt
     6001 taattattcg tgacatcaca tgcattttgc aaaaaataca cttttctttc tgtagaatta
     6061 taggaaagga taaagttatt ttattttagg tttacaattt cgctttagtt aaatgccgat
     6121 gggtaaagaa accctataat aaatttaata ttataatcaa aaaaaaggaa taccttataa
     6181 taaaatgtac cctatagaat agacacttga aaaaagtcta ttctataggg tatttcttgt
     6241 ataataaaag gaaaattggg atcggagaat gttgaaaatg acaaaaaaac tatttacaga
     6301 aagagaaatt caaattctat caaataacct atacgtaaaa tctgtaagtc agaaaggtat
     6361 cacttataca gaggaattta agcatatttt tattgaggaa aatgaaaaag gaaagctacc
     6421 tcgaaatatt tttgaagaat gtggttttga tatagatatg attggaatga aacgagttat
     6481 gtcatcggga agtagatggc gtgctgctta tagaaaaaat ggtgtattgg gtttaaggga
     6541 tacacgtatc gaaaacgctg gaagaactct tgagagagag cttacgttag aagaaaagta
     6601 tgcccgttta gaagccgaac gaaacttact aaaggcggaa aacgaattgc taaaaaaaat
     6661 caaacttatg gaagggagga tgagaaggaa ataacactac cacctagtca gaaattcatc
     6721 ttgattcgtt ctgtcatcat gaaatacaac ttaaggaata tggtcagtca tttgtgtaaa
     6781 gtagctggtg tatcccgttc gggatactat aattactttt cagtttcatc tcaagaacaa
     6841 cggaaacaaa agagtgatcg agatgaaatc ttgaaggaaa ccatattaaa agcacttcga
     6901 tttagaaata gaaacaaagg ggctcgtcag ataaagatga cattggcggg tcagtttcaa
     6961 gttgtctaca atttaaagcg tatccgtaga attatgaaga aatacgagat tatctgtccg
     7021 gttcgcaaag cgaatcctta taaaagaatg cttaaagcta caaaagaaca tcgaatagta
     7081 ccaaatcaat taaatcggga atttaaacaa aataccccag ggaaaacact tcttacagat
     7141 atcacctatt tagtttacgg taagaatcaa agggcctatt tatctacaat tttagacggc
     7201 tcaactaatg aaattttagc ttaccatgtt tcagaacaga tgacattaga gctcgtaacg
     7261 acaactctcc ataaactaaa aaggaatccg cggattcgat tgactgaagg tgcttatatt
     7321 cattcagatc aaggatccca ctacacaagc cctacctatc aaaagctagt taaaaagcta
     7381 aacctaggac aatccatgtc aagaagagga aactgttggg ataacgcccc acaagaatca
     7441 ttttttggtc atctgaaaga tgaagctcat ataaaacctt gcgtgtcctt taatgaattg
     7501 aaacaagaga ttaagaaata tatgacgtat tataatcatt atagatatca atggaattta
     7561 aaaaagatga ctcctgttgg atacagaaat catcttcttg atgttgccta acttttttca
     7621 aaatgtcctt tacaaagggt acagattata ataaaggatt cctttttttt gattatatag
     7681 ctgctattta aaaacaaata atgttataca agcgatctta atccaagact tcatcgtatt
     7741 aactattaaa aaatttagat gttagctata tttctgaagt atacaatgtg accattccat
     7801 ttgttctatt ttcacttgat ataattaatt tggtaatatt cttaggcgca aatcgatata
     7861 tagaaatatt tggaccagga ttattagatt taaagtgaat aacttcttca ttatcaataa
     7921 aaccttgaat atagctttca cttccttcaa aaaattgaaa atgagctgac actgatataa
     7981 tctcgccatt gttctcaaat aaaactattg aatttctata tgtatcaaaa ttaataagtt
     8041 tcatttttga cataattagg atgctccctt ctatgaaagc atgatgatta aagcatacta
     8101 ccatttaaag caattctttt attaccatgt gtaagttcta atgttttatt gagaaaatac
     8161 aagccatctt gctgatgtga aatcataatt aatatattac aaagattgta attttgaagt
     8221 atctcataca taagatttct tgtatcaata tgtaaattag atgctgcttc atctaatatt
     8281 attatatccc tttttgtgag gatagccctt aaaaaggcta taaattgtgc ttgacctcct
     8341 gaaacactgg aaccatcttg tacaattata gtatctaatc cattctcaaa tctgttgaga
     8401 tgtgatgtta aatgatacct tttcattaac ttaactacat cttctttcgt tttatttgtt
     8461 tgtccatata atatgttatc taatatagtt cctttaaaca aaaatatatt ttgtgaaact
     8521 atacctattc tatctctaac actttcttta tgtattaagt tatagtcaat attatttatc
     8581 aatatctttc cactttcagg ttgatataaa cctgttaata attttataaa ggtagatttt
     8641 cctgatccat ttataccatc aattaataac ttgtcaccct tttcaatttg cacgtttaaa
     8701 tgatcaaata tcaaatcact atttccatta tatttaaaac aaacatcttt aaattctatt
     8761 gaattaattg gttctttcat tatatttgta cctagtgtat tttcaacatc taaattgaag
     8821 aactccttaa ttctcttaat actaatacac acgggtttta gagttatatc taagctgcct
     8881 aaagcttggg tagtcgcaag gagtttagcc atataaattg aaaatgaagt atacacccct
     8941 atagtaagct ggttttgtaa aattaaaata cctgatacca gtaatactat tactgtaaca
     9001 aagttatttg ttactattaa attttgcata aagaaaataa aatgtaaatt ttgttttagc
     9061 gcacttttaa ttacattatt taatttactc ttaatcttat tggtttgtat atttttaccg
     9121 tttaataatt ttatatcctc tattccattt aaggtttcat acatttctgc gtttaatact
     9181 gccgatgact cgtatacgtt tgtggtactt ttcgatatca ttttagaaga atgtttggat
     9241 attataaaat atattgggat aataattact atgatacctg taagtttaac acttaaatta
     9301 aacattataa ataaagcaaa gaaaaaatcg aatatacctg aaaaaaccct taataaattt
     9361 ggagaaaata atgcacttac attaccagat tcagcaattc tgctaagaat gtaacctttc
     9421 tccttctgat taatataaga aagaggcgca tctataatat tacttatcat agataatcga
     9481 atttcattaa ctacattttg ttgtacacga gtaaataaat actcataacc tatcgatatt
     9541 aaatagttaa tacaataaat taataagagt ataagagttg tttttaataa ttgatcgtag
     9601 cttttgttta atagtataac tttatcaata atgtacccaa taatatatgg tatcggtgcg
     9661 ataatcaaag aagctataac catcccaatt aaaccaaaag ctaacaaagt ttttgtattt
     9721 ttcaaatacg gatataaaaa taataactct ttataagaaa tttgaatttc atcttgttta
     9781 tttatcttct tattcaccct ctttctcctc ctttgtctat ttattatatt aatttacgaa
     9841 tcaatataat gaggtttata taattccata gatatcttga gaccttatcc cgacgcatta
     9901 tctatggaat tatattggtt tatcctcaga aacttaacaa tattcatctc atccaatcat
     9961 actaattttg cccttaccat taatggctcc ttcaatcata ctaattttgc cctaccatta
    10021 atggctcctt aattatttca gggacatgat ttttaaacca tttacattta tcgccaattt
    10081 cttgtgcttt tataaagctt cttaagaagc atgtactaca aaaacgttta ttttcacact
    10141 ctttacattc ctcagagtcc atttgaggtg cttgcaagtt aaaaaatgca ttaatgtatt
    10201 tgaatttttc gtcataaata tctttaatat tctgttcaaa aacattacct atactgtttt
    10261 tcaaatcatc taaactatgc atagtacaca ttttaatttc accatcaggc gcaatcacaa
    10321 tatgtgatgt tattgcacca caattcctaa tctcagcgcg cgcaccttca tataatgaaa
    10381 caaatttagg atatttttta tttattttca acaatgcttc accatatgtt ttaacatcct
    10441 cttcatttaa ataaagatca ctacatccta aggctcttcc cattggtatt actggagata
    10501 ccccaatact atcaatccct aaattatgta cccattcagc tatatcttct acctcgtgca
    10561 cattcaaatg tgtaactatt gtggcgatcc gcaaacgaac atcattttcg gctaatttca
    10621 ttatgttatt tttaatttta tgaagtgtat taggaacttt aaagaaccaa gtcaaataat
    10681 tatcatctaa gctatgcata tcaatttgca caaatgtttt cgacttattt tttattatta
    10741 tgtccataac tttctcagaa agagctatac cattggtcaa cagtgttatt tgagaaaaat
    10801 ccaagttaag tgcatataac aatatctctt ttagatttgg atgtactgtt atatcaccgc
    10861 ccgtaagttc aattaatttc actcctatat tatttaagtc atctaataag gattttattt
    10921 gatctaagct cattactttt ggctttactg ctccaaaatc tccatagcaa tgacgacatc
    10981 ttacattaca tctgtttgtg atttcaattg aagccacttt tggatatata gtctgttctt
    11041 caattaaatt aactggtaca tttataggtt cttcttgcgt accaatgttc atattgtaaa
    11101 ctttggatac attatttaaa aatgcattta atttcttttc aatacttatt ggatcttcac
    11161 tgtattttaa agacaagaaa gatacaactt gtccatatgt tttagtacca tcaattaact
    11221 caataatttc agtggcggtt ttatttatcg taaatgtatt ttcgttttta agcgtaggag
    11281 cgctttcgtt tgggttttta tgaactacca acatagattc ataatttgat gtgaattttc
    11341 ttatttctag cttttctttc caaaataaat agccattcac tttaatcatc tcctataaaa
    11401 tttaaatttg tttttagttt atgtattaca aaaatcccat actcgttttc gataaatata
    11461 taggacttat tcttaacata actgtttgtc attagaataa gccctaattt aatttcacca
    11521 taaacactct cacattttaa aattttaact tgcagtacta gctccggttg ccgcagtaac
    11581 tagatttaat aactctacag aacatgctgc acatactaag caactccaac aagtccaatc
    11641 ccttggttgt actactggtg tttccattta gaacatctcc tttttggtta tttatttttc
    11701 ttctagaaaa ttcatttgac caaaagtgct cattctctta gtacctttaa ccaaaaaact
    11761 tctaaaagga tattagcttg cagtactagc ccctgttgcc gcagtaacta aatttaataa
    11821 ttccacagaa catgctgcac atactaagca actccaacaa gtccaatccc ttggttgtac
    11881 tactggtgtt tccatttaga acatctcctt tttgattatt tatttttctc ctagaaagtc
    11941 taatttgacc aaaagtgctc attctcttag tgcttttaac caaaaaactt ctgaaaggat
    12001 attagcttgc agtactagcc cctgttgccg cagtaactaa atttaataat tccacagaac
    12061 atgctgcaca tactaaacaa ctccaacaag tccagtccct tggttgtact actggtgttt
    12121 ccatttgacc tacccccttt tctgtattgt gtggtgcgac taaagtataa ctccctatgt
    12181 tttctaaaaa caatcaaaaa attttaaaca ttttgtgtgt gtttctttaa tattttgtga
    12241 catatattta caaaactttc tttttggttt atttaaaata acaaatatct ttattaactg
    12301 atactaaaaa ttttatttat gaaaagttat ttaatcgcag tatatcttgt taaactgctt
    12361 tttataattt ataatgttaa ctgtgtatag tgtgtatggt gtgcattaca taacataaca
    12421 cttatcgata gagaggttgt ttaatgaaaa tagtcttaag taatgtatca agtctgcctt
    12481 tatatcaaca gataaaggag caaattaagg aatccatatt taacaatgaa ttaaaagagg
    12541 gtgaacaatt accatcaatc cgctcacttg ctaacgactt acatgtaagt gtacttacta
    12601 caaaaagagt ttatgcagaa ttagaaacag aaggctttat tattacaaag gttggaaaag
    12661 ggacctatgt agctcctaca aatttagagt tgttaatgga gtccaaacgc cggatggtag
    12721 aagttaaact tactgaagtt tgtcaaatgg ctcgtagtat aggtattcat gcagatgatc
    12781 tccattcaat tttagattta attttagagg aggagaatga aaaatgaatg ttgtgttaga
    12841 agtaaataat ttaaataaat cttacggaaa tttttcgtta aaagatgtta ccttttcact
    12901 taatacagac tgtataacag gatttatcgg tacaaatggt tctggaaaga ccactacaat
    12961 taaagcgatt ttgggtctta ttttaaaaga tactgggaaa attaattttc taggaaaaga
    13021 tatggataag catgaaagaa agtctaaaaa caaaattggt attgtgctag acgagggcta
    13081 tttttatgat gaattaacag taaaggaaat gaaaaatgtt attgctccat cctacactga
    13141 atgggatgaa acagttttcc aaaattatat taaaaagttt aacttaaatc tagaacaaaa
    13201 aatctctact ctatccaaag gaatgcgaat gaaatttgca gttgcattag ccctatccca
    13261 tcatgcagat ctattaataa tggatgaacc aacaagtggc ttggatccat tagtacggag
    13321 tgaattaatg gatattctcc ttgatttcat gaaagagccg gggaaaagcg tatttttttc
    13381 cactcatatt acatctgatt tagataaaat tgctgatatg attattttaa ttgatgatgg
    13441 aaaagtttta gtaaatgatg aaaaagatgt tttaatagac acacatgcat tggtaaaggg
    13501 cgacaaccgc ttaattaata aacaaacaag acctcttttt ttaaatttac atcaaactca
    13561 ctatggattt gaagggatta ctaataaaaa agatgatgta cgtcgactca tgcctgatgt
    13621 attaatagaa agaccaacta ttgaggagat tatgctttca tatattgggg ggaacatcca
    13681 tgttaattaa cctagtgatg aaagactttt tgttagtcaa aaaatatttt ctaatcttac
    13741 tcgtttttgc tgctatagct cctatttatc tttcttcaca attacaatta aacgatggcg
    13801 gtcttgttag ctttctttta accgttattt tgatggaata tattttgttc ggaacggtat
    13861 ccaaatttga ggatcagtac aagggagcgg ctttactttg tgctacccca tacacacgaa
    13921 gcgcatttgt aaaagcgaag tacctttttc tttttgtaat ttttatttgt gcagctatta
    13981 tccgtataat catttcagtt gtcgcaccat cgggtataga aagcttgagc gctagcgctc
    14041 ttggaataac ttttttaact ctaagtattt tatttggtgt actacttcct gttcagttta
    14101 aatttggtta tgacaaaacc aaaatcatat cacttttaac tgctttttta ataccttttg
    14161 ttgctcctac tcttataagg ggactacaat caagtgatat tgatttcaaa agtatttttc
    14221 cattctcacc aactgtccta acatggatgc cttgtttcat ctcaattatt attggtttta
    14281 tatcaatgat aatatctctg aaagtatatg caaaaaaaga tttataattt aaatttgaaa
    14341 tcataggaat gagtaattaa atactttata tatttaatta ctcattccct tttatttaat
    14401 tctcttctct aatgaactta ttcctaaaat acattttatc gatatcaaag tgaataaatt
    14461 tttcaaatca ctaattctct taacatctct tttcattaac gatttagtaa actaaggatt
    14521 atacataata tatcaagagg tgattttatg aaaaaaataa ttaaattcct tctgttaatt
    14581 aacttgattt ccggaacttt catacctatt actacagttc atgctgaaaa taaatcacaa
    14641 tattatacta taatgttgaa gaattatgaa aataaccaaa aactagctag taagtttcaa
    14701 aaatatgata tgcaagtagt ctatagtgtc ccagagattg gtgttataca agtgaaagct
    14761 accgaaaaag caatgaatat tgttcattcg gatcctaata tagattcata taataagtca
    14821 ttacaatcgt ttaattcaag agaagtagca accaatgtct cttcccccct gcccttaaat
    14881 gaaatatggg agaatcaatg ggatatgcaa caagtaaccc ataatggtga tagctataga
    14941 ctatatccag gaactaaaaa tgtaactgtt ggtatcattg attcaggcat tgatataaat
    15001 catcctgatt taaaagataa catttcacct ggatctaaaa atttagtacc taaaggtgga
    15061 tttagagagc aagaatctca agaaacaggt gaattaaatc gcctaataga tctaagagga
    15121 catggaactt ttactgctgg acaggttgca gctaatggtt ttatgaaagg ggttgctcct
    15181 ggtattggaa ttaaaatgta tagagtgttt ggtaatggag caggtgaggc tatttgggtt
    15241 attaaagcca tagttgaagc tgcgaaagat aatgttgatg ttatcaattt aagtttaggc
    15301 gaatacctca tcaatggtat agtatcttct tcagacggtg aatctagtga ggaattatcc
    15361 gaaattaaag cttatagaaa agccattaaa tatgctaaat caaagggaag tattatagtt
    15421 gctgcggctg gtaatgatgc tcttgatgtt actaacaagc aggaaatgaa tgattttttt
    15481 agaaaaaaaa atgaaaatac tggggtaaca tttactggag aagtattaga tgttcctgct
    15541 gaattgccaa atatagtaac agtttcatct gttggtccat ctaaattact ctccttattt
    15601 tcaaattatg gtgaaagttt tatagatatt gctgcacctg gaggagataa tagattattt
    15661 cagcaatatg gtttagaaca gtgggtaaaa aataagttaa tgttaaaaga actaatatta
    15721 actaccgccc ctggtggtgg ctatgctctc tctatagggg tttcacttgc cgctccaaaa
    15781 gtgtcaggtg ctttagcatt aattattgat aaaaataatt tttaaaaaaa tccagataag
    15841 gccgtgagat atctttataa aaatggagtt agcaatgata cccctactaa taaaagtttt
    15901 tttggtaatg gtttgcttga tgtctataaa gcgatttccc aataaaatat atacacttca
    15961 atttggtttt aaactaacaa ttgatagtga ttttttgatg gaacctttat ttaaagcaag
    16021 tctaattgcc ttaaataaag gttttttatt atattgaatt aaatttttcc atatccatct
    16081 attagattcc ctatttagtc attcttggat cccactttta ctaataacct taacaagtgg
    16141 ttatttgcat aattagacta ttgtatccaa aattaaaaaa cactattctt cctttatatt
    16201 tccacagaga gaaaggcgtt tttcccgcag atatttctct aaacttttga gagagatatt
    16261 tatggaagat tgttattccc tatgttcctc taccacttta tagtaatcaa ttttttcttc
    16321 aataaacaat atactactcg gagtataccg agtgtatttt tgtaaatact aaaattgtta
    16381 aatgttaaat cgaggagggt ttgtatgcaa gatcgtaaaa aagctataaa aagtactggt
    16441 tctgttatga aaccagattt tgctgaaaca gatgcacaaa aagtgaaaca agaaattcaa
    16501 aatgatgtaa gagcaggaca aggagcaatg acttcccgag aggcaggggc aatgcgagat
    16561 taagaaaaca ctccttattg gttttttctt ctctagaact ttaaccagta aggagttatt
    16621 cccgaactat tttagctttt tacgtttttc ctttagaaac ataatgcgtt tcgtttgtaa
    16681 atcataggtt aatcttacat cgaatttctc tccattaaat ctattttttt aaactaagat
    16741 tattttcttt cagataatgt attgcatctt tgttcaccga tcttaaatct ataccttgtt
    16801 tctctgctgc aaatgaacat ccacaataac attgacggaa aacatcatat tcattacaca
    16861 tttcaattga acgttgatat ccattacttt ttttgaaatc acttggtaaa taacgcgaat
    16921 cataattttt ttgcacaccg attccaagtt catttattaa ttgactattt ttatttttag
    16981 aaagagtaat ggcactccca aagtaatcaa aacctttttc ttgtgctacc tcagctgaac
    17041 gatccaatct catatcaaaa caagctgaac aacgaagccc gccttctggc tcttctgcca
    17101 aaccttcttc ttttaccatt ttaaaaaata catttgaacg gtagtcatcc tcaagaaatc
    17161 ctactgtgtg cccagtacga tcattgaact tttctacaaa aatcttttgt tcattagagc
    17221 gtcgcatgta ctcacttttc ggatgaatat tcgaattcga gaaaaaaacc gtaatatctg
    17281 catgttctgc aaggaattcc aatgaagcag tactacaagg agcacagcat gaatgaagta
    17341 acacttttgg tctttcgttc cttgcttccc aatcattaat catttttctt aatactttat
    17401 cataatttat tttctgattc ttcattttct ttaaatacgt ttctacatct aacacttctt
    17461 tcacaactaa acctcctgtt tatttttatt tattatatca cttaaattaa ttaataaaat
    17521 atagtaatgt atgtatttat cgatcgtaaa acggttctta tgacctttgg tgatggctaa
    17581 aataatatat gtattctatt acctctattt ctaaaataaa tccttaatcc ttctttttca
    17641 tcacaaaatc ttttggatta ccttttaact ggtaatactt cacgttaaga cgaataacta
    17701 ctacaatgat taccaaaaat cctattatat ataacattgt tccttgctcc gtttcttatt
    17761 gtttagcgaa cttattctgt aaatacttca catgtttatt ttcagtatcc ttatcagtaa
    17821 tatttgcttg caaaatagtc tggtaaatat gctcgacctc gtcttttgtt aatttcacat
    17881 caatatagga ttcgatacat ttttttagat cgttataata taggacatat ttatctttag
    17941 aatgaacatt tactcttttt aggctgcatt ttggatgaaa cgctgcaata gaaatacacg
    18001 gcagctgttg ttccatcacc cattcaattg ttttcatgtg cttatagttt tgtctaaatg
    18061 gattctgaaa agagtgcttc tttctaaaaa taccttgtgt ccatcttgct gccttctcac
    18121 ttccataaat ccagccctcg tagttcttcg tttctataac aaatatacct gtttctgcga
    18181 taacaatatg gtcaatttga gttgtatcac catactctgt atgaaccgtc acatcatgta
    18241 acacccaata cctttcgtga tctaattttc ttaatatacg ttttaccatc ttttctccag
    18301 ctcttccttt ccattttgga gcatgttttt ttaccataat gtttatcggt atcagaagca
    18361 caattagaat taattcaaat attaatactt tcataatata agtccccttt tcacattctt
    18421 gtgtttctat gcattaaacg atatacatgg gtttctaatc ctaaaatata atatgagata
    18481 cataaacctt ttatcaccat ctctatgaat cctaatgcta atgaaacaat gagtccgccc
    18541 cgaaattgaa acggtcttgt caccctccga ttcactggct tttcaatcac tccaaaatta
    18601 gcccaggttg gcaaacgctt ttctacattc tttatagtgc ccattaatcc atatttcaat
    18661 gacaaaatga aacatccaat tagtaaatat ataatagaag aaaaatagat agataagccc
    18721 ataacaataa ttgtgagcag ccaacctatc aagatagaat tacgtaaagc ggtatattct
    18781 cgatttcttt tcaaaacaag cactcctatc aaaataaatt gagttattat taaatatgag
    18841 gtatgaattt ctaatttaaa tattatttta gtttctatct tcctcgtctg ttttgcaggc
    18901 ataccagctc tactacaagt tctgttcatt ctacaaatgg caatcatttt ctatctgtta
    18961 aagcgtagtt gtctgtatat cgaaagatta ccgatacata atctctatca aataaagcaa
    19021 tatatttgca acaaaaaaca attaaaaatc gaataaatta tcctcaataa tgaggagcat
    19081 gaaaccctta ctatttaaac caaagataaa caaaattata tataacagtg tacttaagta
    19141 gcatattacc ccctatacca tatgaaatat ttgcagaata cgaaagaaaa aatgagatgg
    19201 gtagttaaaa ggtactgaat gaacattcag taccttttat atctatatat acttctttac
    19261 atattcgcaa atagccatgg agcgagtacg gctaacatac acaggaaaca agatcccgtt
    19321 atgactcgat tggaccaacg gtaatactct ggctgtttcg tactctcatg aatttttctt
    19381 aaacgaatac ctgcaattaa cataaagggt gtgaaaataa gtgctgttga tttaaacaga
    19441 tttaaaaaat ccgtaaaaat gttcataaac gaaaatacat ccgaactaaa taagaagtat
    19501 acacttaatc tcatcgccat catgctaacg aaagagaaaa tcatactccc agttgcccac
    19561 ttcatccatt gaccattctt tgtaattaac gccataacca taacgataac acctaatatg
    19621 aatgagatag aaaaaatatt tactcctact ttaaaagctg gtgcatacat accctcaatt
    19681 ttttgtataa ttgatgaccc aaatgaatcg tcttttcctg tcgctttttt tcgattattt
    19741 aatccttctt taaaagatga cgaaacatca tttcctttta attcattaaa atccactttt
    19801 acagatgcat gagctgtatg taaaggtatc agtactacga tcataaaaac aaatatacat
    19861 aaaacaccaa tcatcctttt ttctcgcttc acaacacatc acccgctaat ttaggcttaa
    19921 cgctctttaa tttgatttca tttccttccg caacgtaacg cagatctgct gaataataaa
    19981 tattcgcttt tgtatatgct cccataatcg catttgcaat ttcttctttt tccactgcta
    20041 catatgtttc attttcattg taaaacccaa tttcaattcg attaatatta ttatttaata
    20101 ctgttatatg taactctttt aagctattca aacgatttcc taaaccacaa actagcttaa
    20161 atactttgct cgcaagtgtt ggtggcttaa catatgtcgt attaaaatga atagtttcat
    20221 catctataac accatcttcc tcgactgcgc atgtcataat gaaagaatga ttttgttttt
    20281 caatttcttg tagacttaac ttgcgatcaa tgacatattt cagacttgtt gatagatctt
    20341 ctatatattc atctaaatca gtattaaaaa ttttaacctc tgagaattct gggaaaatca
    20401 tgtaagcgtg catgttagaa ctacttttac ttacacgtaa tacctgtacc tgtttctttt
    20461 catagcgcac cgtctgttcc aattttttta ctacattgtt gcttatatga tctattatca
    20521 tatttcatca acctccagta attttaataa aataattttt tacaatctca tgtatataaa
    20581 gcattgcaat atttgctgag gtctcgaaac tcatatttta tgattaataa tcactttaat
    20641 cttaaaacat cttaatatta caatgacgta caatttttca ttatagtcga atattcttat
    20701 atggtgaatc gttctgtttc actcatttgt ataaagataa aaagatattt tatccttata
    20761 caaatgagtg agacatactg tatttcacgc tatttatcta agaaaataaa actaggaaat
    20821 agattttata tacgcactag ttatctatga ttccattcaa ataatgtata aaaattaagc
    20881 aaattccctt caaattctaa atatattcat gcatttctcc tttttttttt agaattacaa
    20941 actatcagaa gtacatatca aaacagacca ataaatacca ttgtaaacat gatttttact
    21001 ctctattctg taaattaact gtactcaaac tattcatctt tgaatctatt ttttcatttt
    21061 tcttctactt gttaattttg aataaagttc tgtccctaaa ctattttcta tacgcataat
    21121 ttttcttacc agatttctaa ttgcaataaa aaaggaagat ccaagtattc atatcactta
    21181 gttcttcctt ttcccctgta taaactacca tcacataatt tacatcgtat ttcttcattc
    21241 gtactctcta ataacttatc tatattaatc aatatatcat ccggctcttt agaatactct
    21301 tttggttcaa ctaatactat tcaaacatta tttttttcgt ttttcatgtt atgaatcata
    21361 aatgatccca cctgcaactt
//
