LOCUS       NZ_CP076499.1          22982 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP076499.1 Enterococcus faecalis strain UAMS_EL53 plasmid
            pUAMSEL1, complete sequence.
ACCESSION   NZ_CP076499
VERSION     NZ_CP076499.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-06-07 19:49:53
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 13951
            Orig. end    :: 36933
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22982
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12982]"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12982
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     cand_cluster    1..22982
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..22982
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     CDS             151..417
                     /locus_tag="ctg1_14"
                     /transl_table=11
                     /translation="MRNRIEELKEQARTELNEWGLIIDGCFEGDFETWIGCYARPKDKP
                     TALDPINEEEAKEQAKYAVNGFPQDFTEWYEWEINNGKLKNLL"
     CDS             579..1355
                     /locus_tag="ctg1_15"
                     /transl_table=11
                     /translation="MDFQNIQTVKELRYALKQYKQTLATTIFDDTQGYISVAFKKEVIE
                     KDGKNVQFLCFYPNYEVALYPVETLLAYLEKLPEQAIVTIKDHDGNYSSLFLTIDETID
                     QGNNYQWLVISDKNSYERFFFTAQESTQEQAFEKMLKELETDHDSTLEVVHNWLCRQTD
                     EALFLGILKEDRTLKGAMTYCIGKAQEQSKDQSSAMVADEVVFSWIKEYFLLEKLPETK
                     AVGKVTTTNKKKPTKKSETKPERKEADEQIDLFECV"
     CDS             1352..2686
                     /locus_tag="ctg1_16"
                     /transl_table=11
                     /translation="MNKKTPKPLTPPKAFFNWCTAQIPTYEWQNKKETILASSRKNCPT
                     IKKRLTKYSRLSFPTKFYSFGIILVRAKRIEIQTHSYWQTITDGTETLIYEPSSLERFS
                     NDTHVKAHYENGHWHEGLLANYGYMSSAYTNTVFYSNNWQEKLTTISELKYLKLPTISR
                     QELAHVYKYRNEIEFLQKIGATTLANEILFDDERNIFGTWHKKVDMRVITKNWLKANKK
                     RLKTTNPTFHMLMLEKTLKERKVARIEGIENYLHYSQIKQLPKEVNLTKFQHWFMRKGE
                     RFSYYMDYLHMLEELNTPFTDDVLFPENLQLAHDNATNTLNLLERELEEQQYQERKKQL
                     KALETEIDDLLFLAPHSLQEIVEEGQVLHHCVGSQHYLEQHTKGKTTIVFIRRKEEPDK
                     PYFTLEYREKRVIQVQGKYNRGHVPEEVEEAIEQWQIEIEKAMPS"
     CDS             2826..3302
                     /locus_tag="ctg1_17"
                     /transl_table=11
                     /translation="MIQLSAVGRLTKGAELRTTTNGKSVANVTLACKRKRPDTNGNVST
                     TFIQCVLWGKPAQVFAKYTQKGALVGVNGELQTRSYDDQQGVTHYVTELVVEDFEFLES
                     KETVQKREEKQHAVPQGQSTPTVNEQPAMNQAPTQQNVYQQPSMNGLSEYGYNQ"
     CDS             4239..4436
                     /locus_tag="ctg1_18"
                     /transl_table=11
                     /translation="MNKEQAFQTLDSLVYAMEKLENESIRSEDNEELEQMLALMNRDWH
                     ELYTIYGKAWEEYRKNALEK"
     CDS             4577..5512
                     /locus_tag="ctg1_19"
                     /transl_table=11
                     /translation="MTLTTEVFHDFLCSSQQTFIFQEEKQTKSLVKIMIDPKSTRFFSV
                     FLNPFLQDGESLSFRQNESIGDVIGIYDSVTDTFFSQAEYLIEWHLKGVDITGFKDLHE
                     VIQQLERELAEQTLAEINQHYNYYYTLEGKYLADLSDWKITTLKNEVRKKLLDGQTTFI
                     IDHSFVQYECTDSEILDLLTEKQATQSRLVKKYLEKNARMLSEHLQKLQFQQQYAKELA
                     ENKQFQKEKEIIQAVQKKGMKTITVTYQISDKELTFKMRNIIDSSRDYFSSYDITNKKE
                     RDAYDTLTREAIDLLKIKQISYGRKVLYAE"
     CDS             5586..5729
                     /locus_tag="ctg1_20"
                     /transl_table=11
                     /translation="MSNKELSKKYQESLKQRREKQTKRERALEGTVIAPLTDKNNRKDK
                     NK"
     CDS             5726..6169
                     /locus_tag="ctg1_21"
                     /transl_table=11
                     /translation="MREVTAQQLLTEFSIIEKMAQSDAIKQRFCLDNYLAEDVKSAINE
                     LNSLYPAYHFEYQEVFGGFGHDLVVTDIAQKVTYDRIPKTRTYGELFQTLAKVYGIHSS
                     AKFHHKPTDRLTEEEFQETIKFYENFDIDTLFSQDDEDKYDES"
     CDS             6159..7022
                     /locus_tag="ctg1_22"
                     /transl_table=11
                     /translation="MKVKRKKQPYWLGSLLSLVIIGFGLLNHLDLSEQLSSFLSNDIFQ
                     EVAKSDKKSLTKKPRNVKTKKSTSAPYDQQQYNQLANLDFQSGGKAAIEVNNGQSSLDI
                     ATWKENKVIYGDLDSLNRTTFVTAYLDRKNLGRSEGRERQVWQPTGWHQKQIDGDPIVN
                     RGHLLAYTSSFNFDIDGNFKIGENGSQDNPKNLATQTAFSNQKVQTHYEKLVRDAQKLK
                     GNKVIYQIVTVFRGKELMPRGYWLQAIDSAGTLNFNVYEYNVQPNVVFNYEEGTSQIDR
                     TMKVRE"
     CDS             7131..8459
                     /locus_tag="ctg1_23"
                     /transl_table=11
                     /translation="MSLKKMEDRSDIVINKVEKRDILILSSFVFVVMLIYNFGIKQMEF
                     GDDAFFLKQFTHDFQSNYYEFLKFRYNEWTSRLVIEIALTQAVQHVFLWRVLNAIAMSI
                     VAIVPALLFNSDNSRRGLIIGTGMSLLIPASMINNAGWIATTTNYVWVMAAALLSIWPI
                     MNYIRGKSVNWVSLILSLVFLIYATNQEQMVVIMLVSLLILAGILFLSKKNILITLPHI
                     AIVIASLVFILTCKGNAARNVQETKQWLPNFSSYSIFDKLQIGYSSTLKALFFEWSPLM
                     LAFVLLILTAGLVKNGTLVKKMISGIPLLTYLICTRFNTIIDQTYDIVSGKTYMSLVVL
                     LTGLVFLYVIGIFGASNNPLEFLSVIFLLILGVGSRIMMGFSPTIWVSGSRTYYFTYVL
                     IMMSGVYLISQLPENNQSRTFKVLFGYFLVLALLLIMMYTKIL"
     CDS             complement(8905..9105)
                     /locus_tag="ctg1_24"
                     /transl_table=11
                     /translation="MIINNLKLIREKKKISQSELAALLEVSRQTINGIEKNKYNPSLQL
                     ALKIAYYLNTPLEDIFQWQPE"
     CDS             9509..9715
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_25"
                     /transl_table=11
                     /translation="MENLSVVPSFEELSVEEMEAIQGSGDVQAETTPVCAVAATAAASS
                     AACGWVGGGIFTGVTVVVSLKHC"
     CDS_motif       9509..9580
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MENLSVVPSFEELSVEEMEAIQGS"
                     /locus_tag="ctg1_25_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9581..9715
                     /prepeptide="core"
                     /locus_tag="ctg1_25_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="2.00"
                     /molecular_weight="4019.5"
                     /monoisotopic_mass="4017.0"
                     /core_sequence="GDVQAETTPVCAVAATAAASSAACGWVGGGIFTGVTVVVSLKH
                     C"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MENLSVVPSFEELSVEEMEAIQGS"
                     /leader_location="[9508:9580](+)"
                     /alternative_weights="4037.6"
                     /alternative_weights="4055.6"
                     /alternative_weights="4073.6"
                     /alternative_weights="4091.6"
                     /alternative_weights="4109.6"
     CDS             9749..9940
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_26"
                     /transl_table=11
                     /translation="MLNKENQENYYSNKLELVGPSFEELSLEEMEAIQGSGDVQAETTP
                     ACFTIGLGVGALFSAKFC"
     CDS_motif       9749..9856
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence:
                     MLNKENQENYYSNKLELVGPSFEELSLEEMEAIQGS"
                     /locus_tag="ctg1_26_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9857..9940
                     /prepeptide="core"
                     /locus_tag="ctg1_26_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="2.00"
                     /molecular_weight="2632.0"
                     /monoisotopic_mass="2630.3"
                     /core_sequence="GDVQAETTPACFTIGLGVGALFSAKFC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MLNKENQENYYSNKLELVGPSFEELSLEEMEAIQGS"
                     /leader_location="[9748:9856](+)"
                     /alternative_weights="2650.0"
                     /alternative_weights="2668.0"
     CDS             10001..12982
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070:lanthionine synthetase C family protein (Score:
                     844; E-value: 2.6e-255)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_27"
                     /sec_met_domain="DUF4135 (E-value: 8.9e-95, bitscore:
                     311.1, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 2.9e-51, bitscore:
                     167.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEDNLINVLSINERCFLLKQSGNEKYDIKNLQAWKERKSVLKQDD
                     LDYLIKYKYESLDNFGLGITPIENFPDKEVAIQYIKDQSWYIFFESILDSYNDSEEQLL
                     EVDASYPFRYFLQYARLFLLDLNSELNICTKEFIINLLENLTQELIHLTSKTLVLDLHT
                     FKKNEPLKGNDSSKRFIYYLKKRFNSKKDIIAFYTCYPELMRITVVRMRYFLDNTKQML
                     IRVTEDLPSIQNCFNIQSSELNSISESQGDSHSRGNTVSTLTFSDGKKIVYKPKINSEN
                     KLSDFFEFLNKELEADIYIVKKVTRDTYFYEEYIDNIEINNTEEVKKYYERYGKLIGIA
                     FLFNVTDLHYENIIAHGEYPVIIDNETFFQQNIPIEFGNSATVDAKYKYLDSIMVTGLV
                     PYLAMKDKSDSKDEGVNLSALNFKEQSVPFKILKIKNTFTDEMRFEYQTHIMDTAKNTP
                     IMNNEKISFISYEKYIVTGMKSILMKAKDSKKKILAYINNNLQNLIVRNVIRPTQRYAD
                     MLEFSYHPNCFSNAIEREKVLHNMWAYPYKNKKVVHYEFSDLIDGDIPIFYNNISKTSL
                     IASDGCLVEDFYQESALNRCLNKINDLCDKDISIQTVWLEIALNIYNPYKYINDLKNQN
                     SNKYIYTGSELNSKIIQACQKIEKKIFKRAIFNKKTNTVNWIDIKLDQDWNVGILNNNM
                     YDGLPGIFVFYVALKYITKNHKYDYVIECIKNSIYTIPSEDILSAFFGKGSLIYPLLVD
                     YRLNNDINSLNVAVEIADMLIEKKPINNGELKNDWIHGHNSIIKVLLLLSEITEDEKYR
                     KFSLEIFEKLSEEPYFNFRGFGHGIYSYVHLLSKFNRIDKANSLLHKIKESYFEEEPKN
                     NSWCKGTVGELLATIELYDDNISNIDINKTIEYKNKDCLCHGNAGTLEGLIQLAKKDPG
                     TYQYKKNKLISYMLNDFEKNNTLKVAGSEYLESLGFFVGISGVGYELLRNLDSEIPNAL
                     LFEL"
     CDS             12994..15138
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 240.8; E-value:
                     4.9e-73)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_28"
                     /sec_met_domain="Peptidase_C39 (E-value: 4.5e-43, bitscore:
                     139.5, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRLKYVAQGEHSECALACITMLLNYYGNQSTLVELREKYGVPKG
                     GLTIKNIRTVFDEYGFDVSTFKSSFSNYLDLPTPVISYWNNQHFVVIEKIKKKKVLILD
                     PASNKRWIDISEFKKNFSNILIYAHKKKTKKEGKRKQFFLKSFIFTKFKRYFFSLIILS
                     FVSQLLLLLIPIATKYSIDNIRSFQEIPTYVLLLILTSFFSVLYVVQYLKSSVVAEFQY
                     EFDFKLMFSYIDKLFSMPLMYFSNRSTGELVFRANLNIYIRQILSQKVITTLIDSLFLG
                     IYLFLMVNYSILLTIIALVLISLIAFLSIINSHTIKRFVDKEIMEQGNVQRIITEAIEG
                     IETIKSANAEKSFLLNWKNMFTSQLLITKNKNRYIAIFGILPEIIQSVMPALFLIIGIK
                     LIINNSLSLGSLIGFVSIVTMVMKPILSLVSSYNDFLLLNVYFQKLSEVLTYEEKNDFN
                     NKKGNVGKEEFIYRVNNVYYTISVFEKNILNGISFDIRKGDKVAIVGRSGSGKSTLLKL
                     LAGLLQPSNGEILYEGYPLSNNSNNRRNIFYVNQNAHIFNETIEKNISLEFKPNSSINE
                     KKRLKESMSKSKMDEVLLGIPQYEKTIVSENGSNFSGGQRQKIALARAFYSNVNTLLLD
                     EPTSAMDNISEFEVFSNLLDEKRTVITVAHRISTVKNFDKIILMDNGEIVCIGKHEDLI
                     ENSELYRSLYYKKQQFGGTK"
     CDS             15135..16373
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075:alkaline serine protease, subtilase family
                     (Score: 216; E-value: 1.9e-65)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_29"
                     /sec_met_domain="Peptidase_S8 (E-value: 4.8e-37, bitscore:
                     120.9, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKRGLTYILISYIFLILGTTGYASDLSNNISFFIDNSQTTAIEE
                     IESELSSEKVDYIQEIGLVSFKNLDDSDRKFIGKYFNVSEGKKLPDFKPEEVNSSILNI
                     NILNKDFKSFNWPYKKILSHIDPVKEQLGKDITIALIDSGIDRLHPNLQDNNLRLKNYV
                     NDIELDEYGHGTQVAGVIDTIAPRVNLNSYKVMDGTDGNSINMLKAIVDATNDQVDIIN
                     VSLGSYKNMEIDDERFTVEAFRKVVNYARKNNILIVASAGNESRDISTGNEKHIPGGLE
                     SVITVGATKKSGDIADYSNYGSNVSIYGPAGGYGDNYKITGQIDAREMMMTYYPTSLVS
                     PLGKAADFPDGYTLSFGTSLATPEVSAALAAIMSKNVDNSKDSNEVLNTLFENADSFID
                     KNSMLKYKEVRIK"
     CDS             16374..17357
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M50"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_30"
                     /sec_met_domain="Peptidase_M50 (E-value: 1.7e-08, bitscore:
                     27.2, seeds: 56, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKFISPMIFTLLLVIFTLVFELNLVSTAYFALLLSIFVHELGHLA
                     FGLFNKVRPESLIFGFIKFSWENQFKIRLNTQWGFFGGLFRYKPTTFNNKKILRLLTGG
                     PIFSLFFTLTFFVKIDFFQYFSLFNFSIFLITAVPFNFNGFMNDGYNIYKLVTKDYIFE
                     MYYIVSNSLLNKYNQSTFLNTTEVCKIIKKNKELPLYVLNTFLLYVIYEYLIDKNNRKL
                     KLIYPILSKEDKILNNKSYLQNFYLANLYMIEYILSVDNKQTFKKINLKILDSISRSRI
                     RYLNFKCSKSDDDEISQSMTEFSNIIKNYSDQMSTMIIAEKQWVQN"
     CDS             17585..17755
                     /locus_tag="ctg1_31"
                     /transl_table=11
                     /translation="MKKFIYRVLENDEVVAIFNEQQYAQDFIAYEKTISDKQFEIEKVD
                     IADWLLQPREF"
     CDS             17769..18386
                     /locus_tag="ctg1_32"
                     /transl_table=11
                     /translation="MAKIGYARVSSKEQNLDRQLQALQGVSKVFSDKLSGQSVERPQLQ
                     AMLNYIREGDIVVVTELDRLGRNNKELTELMNAIQQKGATLEVLNLPSMNGIEDENLRR
                     LINNLVIELYKYQAESERKRIKERQAQGIEIAKSKGKFKGRQHKFKENDPRLKHAFDLF
                     LNGCSDKEVEEQTGINRRTFRRYRKRYNVTVDQRKNKGKRDS"
     CDS             complement(18508..18828)
                     /locus_tag="ctg1_33"
                     /transl_table=11
                     /translation="MKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLNNL
                     IEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLLGI
                     PA"
     CDS             complement(18836..19189)
                     /locus_tag="ctg1_34"
                     /transl_table=11
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRDINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKTGHTSSLCFS"
     CDS             19311..19772
                     /locus_tag="ctg1_35"
                     /transl_table=11
                     /translation="MRIVKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHN
                     NKKMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSE
                     LVSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     CDS             19786..20475
                     /locus_tag="ctg1_36"
                     /transl_table=11
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFEE
                     EDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKNDIE
                     TTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFLRWK
                     SYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNPVAGT
                     YYVVQNI"
     CDS             20600..22951
                     /locus_tag="ctg1_37"
                     /transl_table=11
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQV
                     ELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVYTP
                     YLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLNVNY
                     LEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGNSGNY
                     VRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKGLLSSA
                     GDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTTEELNNI
                     FSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAVDLDMLGE
                     EILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMSTGYSGNLG
                     FPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNYIAKYNQKVI
                     NQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRKIYDEYRNKLT
                     NSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWLGDLMTCWGEVK
                     KLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDSTALSALKTYYCDK
                     GAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFIDKIVNNSLGTDFT
                     YLDFIGDEGKVANGFSEKIIQFQENRSKLN"
ORIGIN
        1 agaaaagaac accagaaatt aagtgaagcc attatcacaa atgacacagt gacgttacta
       61 cttaattatg gttgtttgaa aaatgcgaat gaccgtttat atcaactaga atattttcta
      121 aatcataaag aatggaagga ctgaaagtat atgagaaaca gaattgaaga actaaaagaa
      181 caagcaagaa cagaattaaa cgaatgggga ttgattattg acggttgctt tgagggcgac
      241 tttgaaacat ggataggctg ttatgcacga ccaaaagaca aaccgacagc ccttgaccca
      301 atcaacgaag aagaagccaa agaacaagca aaatatgcgg tcaatggttt ccctcaagat
      361 tttacagaat ggtacgagtg ggaaattaac aatggaaaac ttaaaaattt actataaaaa
      421 aagaaacctt ttgctaacga caaaagattt ctaaaaaggt acttacactt gaattaattg
      481 taactcaagt ataacttacc taacgacctt tgacaagtga aaatttgctc ccctcttaaa
      541 ttttaagagg ggaagcttac aagaaatgag gaaacgttat ggactttcaa aatatacaaa
      601 ctgtaaaaga attaagatac gcactgaaac aatacaaaca aacactcgca actacgattt
      661 ttgatgatac acaaggctat atcagtgtcg cctttaaaaa agaagtgata gaaaaagacg
      721 gaaaaaacgt tcagttttta tgtttttatc caaattatga ggtagctctt tatccagtag
      781 aaacgttact ggcttacctt gaaaagttac ctgaacaagc aatcgttacg attaaagacc
      841 atgacggtaa ctactcgtca ctttttctaa caattgacga aacgatagac caaggaaaca
      901 actaccaatg gctagtgatt agcgacaaaa attcttacga acgatttttc tttacagctc
      961 aagaaagcac gcaagaacaa gcttttgaga aaatgttaaa agaactagaa accgaccatg
     1021 acagtacact agaagttgtt cataactggt tatgccgaca aacagacgaa gcgctttttc
     1081 taggtattct caaagaagat agaacgttaa aaggtgctat gacttactgc ataggaaaag
     1141 cccaagaaca atccaaagac caatcaagcg ccatggtggc ggacgaagtg gttttcagtt
     1201 ggataaaaga gtatttctta ttagagaaat taccagaaac caaagcagtt ggtaaagtaa
     1261 cgaccacaaa caaaaagaaa ccgaccaaaa aatcagaaac aaaacctgaa agaaaagagg
     1321 cggacgaaca aattgatttg ttcgagtgcg tatgaataaa aaaacaccaa aaccattaac
     1381 cccacccaaa gcctttttta actggtgtac tgcacaaata ccaacgtatg aatggcaaaa
     1441 caaaaaggag acaattcttg cgagttctcg caagaattgc cccaccataa aaaaacgatt
     1501 aacgaaatac tcacgattat cgtttccaac gaaattttac tcctttggaa tcattctcgt
     1561 tcgtgcaaaa cgaattgaaa ttcaaaccca tagttattgg cagacgatta cagatggaac
     1621 agaaaccctt atctatgagc cgtcaagcct tgaacggttt tcaaacgata cccatgttaa
     1681 agcacattat gaaaacggac actggcatga gggcttgtta gcaaattatg gttacatgag
     1741 tagtgcttac acgaacactg ttttctattc aaataactgg caagaaaaac taacgaccat
     1801 ttcggaattg aaatacctca agctacctac aattagtcgc caagaactgg cgcatgttta
     1861 taaataccgc aatgaaattg aatttttaca aaaaataggt gcaacgacac tggcaaacga
     1921 aatacttttt gatgatgaac gcaatatttt tggcacatgg cataaaaaag tagacatgag
     1981 agttattact aagaactggc taaaagccaa taaaaagcga ctaaaaacca ccaacccaac
     2041 gtttcatatg cttatgctag aaaaaacttt gaaggagcga aaagttgcga gaatagaagg
     2101 aattgaaaat tatttacatt attcacaaat taagcaatta cctaaagaag tgaacttaac
     2161 caagtttcaa cactggttta tgcgaaaagg cgagcgtttt agctactata tggactattt
     2221 acacatgcta gaggaactga atacaccatt tactgatgat gtgcttttcc ctgaaaactt
     2281 gcaactagcc catgacaatg ccacaaatac gttgaattta cttgaaagag agcttgaaga
     2341 acagcaatac caagaacgaa aaaaacaact gaaagcatta gaaaccgaaa ttgacgactt
     2401 actttttctc gccccacatt cgttgcaaga aattgtggag gaagggcagg tattgcacca
     2461 ttgtgttggt agccaacatt accttgaaca acatacaaaa ggaaaaacaa cgattgtttt
     2521 tatccgaaga aaagaagaac cagataaacc atattttacc ttagaatacc gtgaaaaaag
     2581 agtgatacaa gtgcaaggga aatacaatcg gggacacgta ccagaagaag tagaagaagc
     2641 cattgaacaa tggcaaatag agattgaaaa agccatgccc tcataagggc atggcagata
     2701 gaaggaggtg atttgcctag acaggcaaat cactctcatt tcaaaaaaac ttccacttaa
     2761 caagatattt attgccacta aaaaaggcat gatataaata aaaaatcaga aagaaggaaa
     2821 caatcatgat tcaattatca gctgtcgggc gtttaacaaa aggagccgaa ctacgtacca
     2881 ccactaacgg aaagagtgtc gcaaacgtta cattggcttg taagcgaaaa agaccagaca
     2941 ctaacggaaa tgtgtcgacc acatttattc aatgtgtttt atggggcaaa cccgcccaag
     3001 tctttgcaaa atacacgcaa aaaggcgcat tagttggtgt aaatggggaa ctacaaactc
     3061 gttcgtatga tgaccaacaa ggcgttacgc attatgtgac agaattagtt gtagaagatt
     3121 ttgagttttt agagtccaaa gaaaccgtac aaaaacgaga agaaaaacaa cacgcagtcc
     3181 cacaaggaca atcaacccca acggttaatg aacaaccagc aatgaatcaa gcaccaacac
     3241 aacaaaatgt ctaccaacaa ccgtccatga acgggttgtc tgaatatggc tacaatcaat
     3301 agatctgttt tttcatgcgc gccacactcc caccgccacc gccgtttagg cgcgcatgaa
     3361 aaaaggtagg cattcgccta ccttttcgca caaaatgtgg tataataatt atgtaaagag
     3421 gacgtactgg taatacgccc tcattgatag caccgctaaa gacggtggca gagtttttat
     3481 aagttattta gaaataaccg gtctcctgct aaagtgacgg ttatttcttt ttgtctttat
     3541 agttcagaat ggcaacaatg gttgtgatta gggtcaatgt aaacccacca aacgcaagca
     3601 ttagttgcaa actttccgaa acggacaaaa ggcttctcct ttctatagat tttggaagta
     3661 cgttcatacg caccacctca ctttcgattg gatagccacc gtcattaaac tttactatca
     3721 attctattat agcataaaaa gccttgtatt gcttgcaata caaggctttt tacataaaga
     3781 agaatcaaga gaaaagagct gtttcttcct tactccaacc gccaccgccg ttcggaagaa
     3841 agccttgttt cacaaggcaa aggtcaagaa cattccggtc aaaaatttct tttctgatgt
     3901 cagaacggtg tcacgcagcc tttttcgttt tcaggccgtt ccttttgccg tgtgtaacgt
     3961 gctgttcact gtttgttaca gtaccatagc cagtcgaaaa aacaagggta tataaacgag
     4021 caagctcgcc cttgtttttt ctttatgtct acggtccttt ctcggcacag cgaacgacac
     4081 gaacacactg gcgaaaatga acaacctaat cgaaaacgaa aaaggggggg agactacacc
     4141 gtttgacgaa aagaaatttt tgaccgtcca gcttcacttc ctcaaacgcc taacaaaaat
     4201 ggttgttcaa aaatcaaaac cgaaagaagg aaaaccaaat gaacaaagaa caagcctttc
     4261 agacattaga ttcacttgtt tacgccatgg aaaaactaga gaacgagagt atccgctcgg
     4321 aggataacga agaattagag caaatgttgg cattaatgaa cagagattgg cacgaactct
     4381 ataccattta tggaaaagca tgggaagaat atcggaagaa cgcccttgaa aagtaaaaaa
     4441 aaagaaacct tttgcttacg acaaaagatt tctaaaaagg tagttatatt taacaaacta
     4501 tagattttaa gtataactta cctacgtttc tttgacaagt acaaaaaaaa tcaaaaagag
     4561 aaagcaggta agaattatga cactaacaac cgaagtattt catgactttt tatgtagcag
     4621 ccaacaaacc tttatttttc aagaggaaaa acagacaaag tcgctggtta agataatgat
     4681 cgacccgaaa agtacccgct ttttctccgt ctttttgaat ccctttttac aggacggaga
     4741 gtccctttcc tttcggcaaa atgagtcaat aggagacgtt atcggcatat atgacagcgt
     4801 gacagataca ttcttttcac aagcagagta tttgattgaa tggcatttaa agggtgtaga
     4861 tataacaggt tttaaagatc ttcacgaagt gattcaacag ctggaaagag aactggcaga
     4921 acaaacgctt gctgaaatca atcaacacta caactactat tacacactgg aaggaaagta
     4981 tctagcggac ttatcagatt ggaaaataac aacactaaaa aatgaagtgc gaaaaaaact
     5041 actcgatggg caaactacgt tcattataga tcattcgttt gttcagtacg aatgcacaga
     5101 cagtgagata ctagacttac taacggagaa acaagctaca caatcacgat tagtaaaaaa
     5161 atatttagag aaaaatgcaa ggatgttgtc tgaacactta caaaaactac agttccaaca
     5221 acagtatgca aaagaattag cagagaataa acaattccaa aaagaaaagg aaattattca
     5281 agcagtgcag aagaaaggaa tgaaaaccat tacggtgacg taccaaattt cagataagga
     5341 actgacattc aagatgagaa acatcataga tagcagtcgt gattacttct cgagttacga
     5401 tattaccaac aaaaaggaac gtgacgccta tgatacattg acgcgtgaag ctattgattt
     5461 actaaaaatt aagcaaatta gctacggacg aaaagtttta tatgcagagt aaaaacaact
     5521 aaatcaaaag gggtcctaag agtagaaaat ttctactctt aggaattgta aaggagaagc
     5581 gaaaaatgtc taataaagaa ttaagcaaaa agtatcaaga aagtttgaaa caacgccgag
     5641 aaaagcaaac aaaacgggaa cgtgcgttag aaggaacagt tattgcccca ctcaccgata
     5701 aaaataatcg aaaggacaaa aacaaatgag agaagtaacg gcacaacaac ttttaacaga
     5761 attttccata atagaaaaaa tggcgcaatc agacgccatt aaacaacgtt tttgtttgga
     5821 taactatcta gcagaagatg tgaaatctgc tattaatgaa ttgaacagtt tatatccagc
     5881 ataccatttt gaataccaag aagtatttgg tggattcggt catgatttag tcgttaccga
     5941 tattgcgcaa aaagtaacat acgatcgtat ccctaaaaca cgtacttatg gcgaactttt
     6001 tcaaacacta gcaaaggttt acgggattca ctcaagtgca aaatttcatc ataaaccaac
     6061 agatcgatta actgaggaag aatttcaaga aacaatcaag ttctatgaaa actttgatat
     6121 agatacatta ttcagtcaag atgatgagga caaatacgat gaaagttaaa agaaaaaaac
     6181 agccctattg gttaggtagt ctattgtcct tggtgataat tggttttgga ttgttgaatc
     6241 atttagactt atcagagcag ctctcgtctt ttttatctaa tgatatattt caagaagtgg
     6301 cgaaatcaga taaaaagtca cttacaaaga aaccaagaaa tgtaaaaaca aagaaatcca
     6361 caagtgcgcc atacgatcag caacaatata atcaattagc taacctagac tttcaaagtg
     6421 gcggaaaagc cgctatagag gtcaataacg gacaatctag tttagatatt gccacgtgga
     6481 aagaaaacaa agtgatttat ggagacttag attctttgaa ccggacaaca tttgtgactg
     6541 cctaccttga taggaagaat ttaggacgtt ctgaaggacg agaacggcaa gtctggcaac
     6601 cgactggttg gcaccaaaaa cagatcgatg gagatccgat tgtgaatcgc ggacatttac
     6661 ttgcatatac gtccagcttt aactttgata ttgacggaaa ctttaagata ggtgaaaatg
     6721 gaagccaaga caatcccaaa aacctggcaa cacaaacagc tttttctaat caaaaagtgc
     6781 agacgcacta tgagaaacta gtcagagatg cacaaaagct taaggggaac aaagtcattt
     6841 atcagatcgt gacagttttt cgtggaaagg aattaatgcc tcgaggttat tggttacaag
     6901 cgattgacag tgcgggtaca ctgaatttca atgtttatga atataatgtg cagccaaacg
     6961 tcgtgttcaa ttatgaagag ggtacaagcc aaatcgatag aacaatgaaa gtgagggagt
     7021 agcaatgact aaagaagaaa aaataatatt gattgtacgt aatagtgact ttacgtatga
     7081 agaattagaa aagcttccaa tgtctagtat cgatagtatt tataaagcgc atgtccttga
     7141 aaaaaatgga ggataggagt gacatagtga taaataaagt ggaaaagaga gatattttaa
     7201 ttctcagtag ttttgtattt gtggtaatgt taatttacaa ttttggtatt aaacaaatgg
     7261 aatttgggga cgatgcgttt ttcttaaagc agtttacaca tgattttcaa agtaactatt
     7321 atgaattttt gaagtttagg tacaatgaat ggacgtctcg attagtgatt gaaatagctc
     7381 taacacaagc ggtacaacac gtatttttgt ggagagtttt aaatgctata gcaatgtcta
     7441 tagtggcaat tgtccctgca ctactgttta actcagataa tagtcgaaga ggattaatta
     7501 taggtactgg catgtcatta ttaattcctg cttcgatgat aaataatgca ggatggatag
     7561 caacaacaac aaattatgtt tgggtcatgg cagcagcgtt gttaagtatt tggcctatta
     7621 tgaactatat aagaggaaaa agtgtaaatt gggtatctct tattttatcg ttggtgttct
     7681 tgatttatgc tacaaatcaa gaacaaatgg tagtcattat gttagtttct ttattaattt
     7741 tagcgggtat tctatttttg tctaaaaaga atatcctgat aactttacct catattgcta
     7801 ttgtaatcgc tagccttgtg tttattttaa catgtaaggg gaatgcggca agaaacgtcc
     7861 aagaaacgaa acaatggtta cctaattttt ctagctacag tatttttgat aagttacaaa
     7921 tagggtattc gtccactttg aaagctttat tttttgagtg gtctccattg atgttagctt
     7981 ttgtattgct aattcttact gctggactag taaaaaatgg gacattagtc aaaaagatga
     8041 ttagtggaat accgctattg acgtatttga tttgtacaag atttaatacg attattgatc
     8101 aaacttatga tatagtttca ggaaaaacat atatgtcact agtagttctt cttactgggt
     8161 tggtttttct ttatgtaata gggatttttg gggcaagtaa taatccctta gaatttttat
     8221 cagttatctt tcttcttatt ttgggtgtag gaagtcgtat tatgatgggg ttctctccta
     8281 ccatatgggt atctggatca aggacttact atttcactta tgttcttata atgatgtcag
     8341 gtgtctattt aataagtcag ctacctgaaa ataaccaaag tagaaccttt aaagtgctat
     8401 tcggatattt tctggtattg gctctattat taataatgat gtatacaaaa atattgtaaa
     8461 atgttttgct aaactttcga cagttgttga aaggacagtg tgtatactgt agaataatta
     8521 caagtcactt cagatttaac tattttctta cagactgaat taatcaatca tttagttcta
     8581 tgagtatgcg ttagaaatga aaggctaaaa taagttataa ccttagagac tgtctccccc
     8641 caaaaagaga tagtctttac tatacatttg agcctagttt ttatttaaat gaatgtaatc
     8701 ataagtgagg gttttactga taaaaaatca gttatgatta aagtataaaa caacagtcat
     8761 aattatttat gctttaaaat ataaactgtt actatgccaa caattattcc taaaaataaa
     8821 atcagaaggg atataaactt tttcttcata cgaagcacct ttcttttaat ttaaatattc
     8881 tgtggtgaaa tttaaaaatc ttttttattc aggttgccat tgaaaaatat cttctagtgg
     8941 agtattcagg tagtaagcaa tttttaatgc taactgtaaa gaagggttat atttattttt
     9001 ttctatacca ttaatagttt gtctgctaac ttctaataaa gcagctaatt cactttggct
     9061 aatttttttt ttctctctaa ttaattttaa gttattgatt atcatttatg aagtcctctt
     9121 gttgaaaaaa agtagtaaca gagagtgcaa tatcattgat agagagaagt aatagtagat
     9181 aaaattaaag agatagtttt tagtaataac attaggtaga aaaagaaaaa tagcaactac
     9241 tataagtatg gaaaagttaa taaataagta catgtaagta gatgttaagg aaattgtata
     9301 taaaattcgc tcatcttttt ttgaatcagt cagattaaaa acaaagtaga ctacagaaat
     9361 gatatccaat aaaaaaataa aaatagccat tttggttcct cctttttgtc aagtgacact
     9421 tgacaaaaga ttaaaagctc tataatatta aattgtaaca tattatgtta tgcaatatac
     9481 aacaatttta tgatggaggg taagaattat ggaaaattta agtgtagttc ctagttttga
     9541 agaactaagt gttgaggaaa tggaagcgat tcaaggtagt ggagatgttc aggctgagac
     9601 aacaccggtg tgtgctgttg cggcgacagc tgcagcaagt agtgctgctt gtggctgggt
     9661 tggtggcggt atttttactg gagtaactgt agttgtgtct ttaaaacatt gttaaaatat
     9721 actataaaac ttagtgaggt gaagcacagt gctaaataag gaaaatcaag aaaactatta
     9781 ctctaataaa ttagaacttg ttggtccttc ttttgaagag ttaagtttag aagaaatgga
     9841 agcgattcaa ggtagtggag atgttcaggc tgagacaact ccagcatgtt ttaccatagg
     9901 cttaggagta ggtgcattat tttcagctaa attttgctaa tttatatatt aagagggcta
     9961 gtgaaactag ccctcttata cataaaaaag gagtgcttac atggaagata atttaataaa
    10021 tgttttaagc ataaatgaaa gatgcttttt actaaagcaa agtggtaacg agaagtacga
    10081 cattaaaaat ttacaagctt ggaaagaaag aaaaagtgtt cttaaacaag atgatttaga
    10141 ctacttgatt aaatataaat atgaatcact ggataatttt ggattaggaa taacacctat
    10201 tgaaaacttt cctgataaag aagttgcaat tcaatacatt aaagatcaat catggtatat
    10261 tttttttgaa tccattttag attcttataa tgatagtgaa gagcaattat tagaagtaga
    10321 tgctagttat ccttttagat atttcttaca atatgctcgt ttatttttac ttgatttaaa
    10381 ctcagagtta aatatttgta caaaagaatt cattattaat ttattagaaa atctaacaca
    10441 agagcttatt cacttgacaa gtaaaacatt agtgctagat ttgcatactt ttaaaaaaaa
    10501 tgaacctcta aagggaaatg atagtagcaa gcgatttatc tattatctaa aaaaaagatt
    10561 taactctaaa aaagatataa tagcttttta tacatgctat cctgagttga tgcgtattac
    10621 tgttgttaga atgagatatt ttttagataa tactaaacaa atgcttataa gagtgactga
    10681 agatttacct agcatacaaa attgttttaa catacaatcc tcagagctta actctatatc
    10741 agaatcacag ggagactctc atagtcgcgg aaatactgtt tctacactaa ctttttcgga
    10801 tggaaagaag atagtataca agccaaagat taatagcgag aataaattaa gcgatttttt
    10861 tgaattttta aataaagaat tagaggcaga tatttatata gttaaaaaag ttactagaga
    10921 tacctatttc tatgaagaat atatagataa tatagaaata aataacacag aagaagtaaa
    10981 aaaatattat gaaaggtatg gtaaactaat cggaatagct ttcttattta atgtaacaga
    11041 cttacactat gagaatataa tcgctcatgg agaataccct gttatcatag ataacgaaac
    11101 tttttttcaa caaaatattc ctatagagtt tggtaatagc gcaacagtag atgctaaata
    11161 taaatattta gattctataa tggtgacagg gctagtacca tatttagcga tgaaagataa
    11221 gtcagattcg aaagatgaag gggttaacct tagtgcgtta aactttaaag agcaaagcgt
    11281 accgttcaag atattaaaaa ttaaaaatac atttactgat gaaatgcgtt ttgaatatca
    11341 aacacacatt atggatactg caaaaaatac tccaattatg aataatgaaa aaattagttt
    11401 tatcagctat gaaaaatata tagttactgg tatgaaaagt attttaatga aagcaaagga
    11461 ttctaagaaa aaaatattgg catatattaa taataattta caaaatctta tagttagaaa
    11521 tgtaatcaga ccaactcaaa gatatgctga tatgttggaa ttttcatacc atcctaattg
    11581 cttttctaat gcaatagaga gagaaaaagt acttcataat atgtgggcct atccatataa
    11641 gaataagaag gttgttcatt acgaattttc agacttaata gatggggata tacctatttt
    11701 ttataacaat atctcaaaaa catcattaat agctagtgac gggtgcttag tagaagattt
    11761 ttatcaagaa agtgctttga atagatgcct aaataaaata aatgatcttt gtgataaaga
    11821 tatttctatt caaaccgttt ggctagaaat tgctttgaat atttataatc catataaata
    11881 tattaatgat ttgaaaaatc aaaattcaaa taaatatatt tatactggct cagagctaaa
    11941 tagtaaaatt attcaagcat gtcagaagat agagaaaaaa attttcaaga gagctatttt
    12001 taataaaaaa accaatactg taaattggat tgacataaaa ttggatcaag attggaatgt
    12061 gggcatccta aataataata tgtacgatgg attgcctggt atattcgtat tttatgtggc
    12121 tcttaaatac attacaaaga atcataaata tgattatgta attgaatgta taaaaaattc
    12181 aatttataca ataccatctg aagatatatt gtcagctttt tttggaaaag gaagtttaat
    12241 atatccttta cttgtagatt accgcttaaa taatgatata aactctttaa atgtagccgt
    12301 agaaattgca gacatgttga ttgaaaagaa accgataaat aatggcgagt taaaaaatga
    12361 ttggatccac gggcataata gtataataaa agttttatta ttgttatccg agataacaga
    12421 ggatgaaaaa tatagaaaat tttcattaga aatttttgaa aaattatccg aagaacccta
    12481 ttttaatttc agaggattcg gacacggtat atatagctat gtccatcttc tatcaaaatt
    12541 caataggata gataaggcaa attctttact tcataaaatt aaagaatcat actttgaaga
    12601 agaacctaaa aacaatagtt ggtgtaaggg aactgtaggt gaacttttag cgacaattga
    12661 attatatgat gataacattt caaatataga tattaataaa accatagaat ataaaaataa
    12721 agattgtctg tgccatggaa atgcaggtac tttagaaggt ctaattcaat tagctaaaaa
    12781 agatcctgga acttatcagt ataaaaaaaa taaacttatt agctatatgt taaatgattt
    12841 tgaaaaaaat aatacactaa aggttgccgg aagtgagtat ttagaatcac taggattctt
    12901 tgtaggaatc agtggtgtgg gttatgaatt attgagaaac ctagattctg aaattccgaa
    12961 tgcattactt tttgagttat aagaggtgta attatgaaaa gattgaagta cgttgcgcaa
    13021 ggagagcata gtgaatgtgc tttggcatgt atcactatgc tacttaatta ttatggtaat
    13081 caaagtacac tagtagaact aagggaaaaa tatggggtgc ccaaaggagg actaactatc
    13141 aagaatattc gtactgtctt tgacgaatat ggatttgatg tatcgacatt taaatcaagt
    13201 ttttcaaatt atttagatct tccgactcct gtaataagtt attggaataa tcaacatttt
    13261 gtggtcatag agaaaataaa aaagaagaaa gtattaatct tagatcctgc aagtaataaa
    13321 cgctggattg atatttcaga attcaaaaaa aatttttcaa atatattaat atacgcacat
    13381 aagaaaaaga ctaaaaaaga aggcaaaagg aaacagtttt ttttaaagtc atttattttt
    13441 acaaaattca aaagatattt ctttagttta ataatattat catttgtttc acaactttta
    13501 ttactcttaa ttcctattgc aacaaagtat tcgatagata atattagatc ttttcaagaa
    13561 attcctacct atgttctgtt attaatatta actagttttt tttctgtttt atatgtagtt
    13621 caatacttaa aaagctctgt agtagcagaa tttcagtatg aatttgattt taaattaatg
    13681 ttttcttata ttgataaact ttttagtatg ccactaatgt attttagtaa tagatcaact
    13741 ggagaattag tgtttagagc gaacttaaat atttatatta ggcaaatatt gtctcaaaag
    13801 gtaataacaa ctttaataga tagtcttttt ttagggatat atttgttttt aatggttaac
    13861 tattctattt tactgacaat aatagctctt gttctaatct ctttaatagc ttttttaagt
    13921 attataaatt cgcatacaat aaaaagattt gtagataaag aaataatgga acaaggaaac
    13981 gtccagagaa ttattacaga agcaattgaa ggaattgaaa ccattaaatc tgctaatgca
    14041 gaaaagagtt ttttgttaaa ttggaaaaac atgtttacgt ctcaactatt aattacaaaa
    14101 aataaaaata gatatatagc tatttttgga atattaccag aaatcataca aagtgtaatg
    14161 ccagctctat ttttaataat aggtattaaa ttaataatca acaattcttt gtcattagga
    14221 tcactaattg gttttgtttc tatagtaaca atggttatga agccaattct aagtttggtt
    14281 tcctcttata atgactttct actattaaat gtatattttc aaaaattatc tgaagtttta
    14341 acttatgaag aaaaaaatga ttttaataat aaaaaaggaa atgttggaaa agaagagttt
    14401 atttataggg ttaataatgt ttactatact atatctgttt ttgaaaaaaa tattttaaat
    14461 ggtatttctt ttgacataag aaaaggggat aaagttgcta ttgttggtag aagtgggtca
    14521 gggaaatcta ctttactaaa actattggct ggattgttac aaccttctaa tggagaaata
    14581 ttgtatgaag gctatccttt atcaaacaac tccaataata gaagaaacat tttttatgtt
    14641 aatcaaaatg cgcatatttt taatgaaact atcgaaaaaa atatttcttt agagtttaaa
    14701 ccgaattctt ctataaatga gaaaaaaaga ctaaaagaaa gtatgagtaa atcaaaaatg
    14761 gatgaggtac ttttaggaat tcctcagtat gagaaaacta tagtatcaga aaatggtagt
    14821 aatttctctg gtggtcaaag gcaaaagatt gctttagcta gagcgttcta ttctaatgtg
    14881 aatacattac ttttagatga gcctacatct gcaatggata atatttcaga atttgaagtt
    14941 ttttctaatt tattagatga gaaaagaaca gttattactg ttgctcacag aattagtacc
    15001 gtgaaaaact ttgataaaat tatattaatg gataatggtg aaatagtatg tattggaaag
    15061 catgaagatc ttattgaaaa tagcgagtta tatcgttcac tgtattacaa aaaacaacaa
    15121 tttggaggta caaaatgaaa aaaagaggat tgacttatat tttaatctca tatatttttt
    15181 taatattagg aacaacaggt tatgcatcag atctctcaaa taatatttca ttttttattg
    15241 ataattcgca aacaactgct atagaagaaa ttgagtctga attatcttct gaaaaagtag
    15301 attatataca ggaaatagga ttagttagtt ttaaaaacct ggatgatagt gataggaagt
    15361 ttataggtaa atattttaat gtttcggaag ggaaaaaatt accagatttt aaacctgaag
    15421 aagttaatag ttctatttta aacattaata ttttaaacaa agattttaag tcttttaatt
    15481 ggccatataa aaaaatttta tctcatattg atccagtgaa agaacaacta gggaaagata
    15541 taaccatagc tctaattgac tcggggattg ataggcttca tcctaatctt caagacaata
    15601 acctaagatt aaaaaactat gttaatgata ttgagttaga tgaatatggt catggtacac
    15661 aagttgctgg agtaatagac acgattgctc caagagtgaa tttaaattct tacaaggtga
    15721 tggatgggac agatggaaac tctataaata tgcttaaagc tatagttgat gctacaaatg
    15781 atcaagtaga tataataaat gtgagtcttg gatcatataa aaatatggaa atagatgacg
    15841 aaagatttac tgtagaagca ttcagaaaag ttgttaacta tgcaagaaaa aataacattc
    15901 taattgttgc atcagcagga aatgagtcgc gtgatataag cactggtaat gaaaaacata
    15961 taccaggagg actagagtct gtaattaccg tcggagctac aaaaaagagt ggtgatattg
    16021 ctgactattc taattatggg tctaatgtat ctatatatgg tcccgcagga ggatatggtg
    16081 acaattacaa aataacagga caaattgatg ctcgtgaaat gatgatgact tattacccta
    16141 catcgctagt ttctccacta ggcaaagctg ctgactttcc agatggttat acactttctt
    16201 ttggaacaag tttagcaact ccagaagtaa gcgcagcttt agcagctatt atgtcaaaga
    16261 atgtagataa ttctaaagat tcaaatgaag tattaaatac tttatttgaa aatgctgatt
    16321 cttttataga taaaaatagc atgcttaaat acaaagaggt gagaataaaa tagatgaaat
    16381 ttatatctcc gatgatcttt acgttacttc tcgtaatctt tactcttgtt tttgaattaa
    16441 atttagtgtc tacagcatac tttgccttgt tattgtctat ctttgtacat gagttagggc
    16501 acttagcttt tggattattt aataaagtta gaccagagtc attaatattt gggtttataa
    16561 aattttcgtg ggaaaatcag tttaagatca gattaaatac acagtgggga ttttttggtg
    16621 gattatttag atataaacca actacgttta ataataagaa aattctgagg ttgttaaccg
    16681 ggggaccaat atttagtctt ttttttacat taaccttttt tgtaaaaatt gacttttttc
    16741 aatatttttc tttatttaat ttttcgatat ttttaattac tgcagttcct tttaatttta
    16801 acgggtttat gaatgatgga tacaatatat ataaattagt tactaaggat tatatttttg
    16861 aaatgtatta tattgtatca aatagcttac ttaataaata taatcagtca actttcttaa
    16921 atacaactga ggtatgcaaa ataataaaaa aaaataaaga attaccatta tatgtgctaa
    16981 atacattctt attgtatgtt atatatgagt atttaataga caaaaataat aggaaattaa
    17041 aactaatata cccaatactt agtaaagaag acaagatact gaataataaa agttatttac
    17101 agaattttta tttggctaat ttgtatatga tagaatatat cttatctgta gataataaac
    17161 aaacttttaa aaaaataaat ttaaaaattc tagactcaat tagtagatct agaattagat
    17221 atctaaactt taaatgctca aaaagtgatg atgatgaaat aagccaatca atgacagaat
    17281 ttagcaatat cataaaaaat tattcagatc aaatgtcgac tatgattata gcagaaaaac
    17341 aatgggttca aaattgagat aagaaaccag ctagactgtc gacgtaaaat gataggctaa
    17401 caaaagtgat gtgtgcttgc tacgattttt atacagtatt tcatgatgta ataaataaat
    17461 tttctgttaa aatatattaa ctaaaagaac caacagggta tacttatttg tcctaatatg
    17521 attttagcag tataattgac ttggtgaata ggtcatttaa gttgagcata ataggaggag
    17581 taaaatgaaa aaatttattt atcgagtttt agaaaatgac gaagtggtgg ctatttttaa
    17641 tgaacaacaa tatgcgcaag attttatcgc ttacgaaaag acaatttctg ataagcaatt
    17701 tgaaattgaa aaagtagata tagctgattg gttattgcaa ccgagagaat tttagaggtt
    17761 ggttgaaaat ggctaaaatt ggttatgcac gtgtcagtag caaagaacag aacttagatc
    17821 ggcaattaca agcgttacag ggcgtttcta aggtcttttc agacaaatta agcggtcaat
    17881 cggtcgaacg tccacaatta caagctatgc ttaactatat tcgtgaaggg gatattgttg
    17941 tagttactga attagatcga ttaggacgga ataataaaga attaacagaa ttgatgaatg
    18001 ccattcaaca aaaaggagca acgcttgaag ttttgaattt gccctctatg aatgggattg
    18061 aagatgaaaa tttaaggcgt ttgattaata atttagtgat tgaattatat aagtatcaag
    18121 cggaatcaga acgcaaacgt attaaagaac gacaagccca agggattgaa atagctaagt
    18181 caaaaggaaa attcaaaggt cgtcagcata aatttaaaga aaatgatcca cgtttaaaac
    18241 atgcttttga tttatttttg aacggttgtt ccgataaaga agttgaggaa caaactggaa
    18301 ttaatcgcag aacgtttaga aggtatcgta aaagatataa cgtgacagtc gatcaaagaa
    18361 aaaacaaggg aaagagggat agttaatgag tacagttatt ttagctgaaa aaccaagcca
    18421 ggcgttagcc tatgcccagg catttaatca gagggttctg ttgcaaagtt ttaaataaag
    18481 aataaaatcc cttacggtat ctatgattta agctgggatt cccaataata ccttgatttc
    18541 agtacagacc gaaaacccga agagagtgcc ttcttttcgg gttttcttat ataatcctcg
    18601 aatggcttcc atgcctttaa tcgtggtaga ggcagtgcgt aaacttcgat agaatttatt
    18661 gcgtctcttt actggacgat ggtcttgttc aatcaaatta ttcaggtatt taatggtacg
    18721 atgttctgtc ccttgataaa agccgtattc ttttagtttc ttaaaggcac ttgtaataga
    18781 gggggcttta tctgtgacta caaccttcgg ttcatcaaac tgcttcacta accgcttaag
    18841 aaaagcatag gctgcttgtg tgtcccgttt ttttacgtaa ccaaatatcc aaggttaaac
    18901 catctgcatc gatggctcga tacaaataat gccattttcc tttaattttg atgtacgttt
    18961 catccatttt ccatgaataa aaggattttt tatttttctt tttccaaatt tgatagagta
    19021 gtttgccata ttcttgcacc caacgataaa tcgtcgtatg agaaacgtta atgtcacgat
    19081 catataagat ttcttgaact tcacgatagc taaggttata acgaagatag tagcccacgg
    19141 ctacaataat cacatcctgc tgaaattgct ttcctttaaa atgattcatc gttattcctc
    19201 ctgctatctt tttctattat tctatcttat ttgatagtag atttaaaact ttgcaacaga
    19261 accaattatc ttatcgtaga tatatattat aaatttaata agaaagcgag gtgagaatcg
    19321 tgaaaaaaac gatactaagt attttttcag tatttacaat attaattggg ggctattttc
    19381 ttttgaattt agattctgtt aattcaaacg ctcaaataaa agatcaaaga gtagctgaac
    19441 ataataataa aaaaatgagt ttgaccaaaa atatctattc tatgtcagat gaagaattgt
    19501 ataaagaatt tggtgattta tccggggaac agttagaaga aagtattcca ggaattagtg
    19561 actcagataa aattgttgtc ttgtctgctg gtgggcaatt aatgggagat ggcaaatccg
    19621 aattagttag ttataaacaa aatcacagac agtttattga tgttaatact gattccaacg
    19681 ctatttcgat taaggatcta aaagagcttt taaatagtaa aagaaatgaa ttaaagcaga
    19741 taaaagaaac taattcagtg gaattagagt aaaggaagat tcattatgaa aaagattttt
    19801 ggtgtttctg ttgggctact tatgatgtta acatttggaa atgcagtata tgctgctgag
    19861 aaagaagtta tttcagatcc agagcagtac gcctcacgat actttgctga ttttgaagaa
    19921 gaagataaag tacttgcatt gccagaaggt ggttttttaa aaggggaagc taaaattgta
    19981 tctatggata atccagatat aattcaaggt tcatataatt cagaaactga tcctgcttca
    20041 gtttcagtga cagaagcaaa aaaaattgtt gctgaaaaat tcaaaaatga tattgaaact
    20101 actccaatta tgcctcgagg agcatttcca cccgatgttg gtactagcgg acaccttctt
    20161 gtactagcag gaggaggaag ctataaatca cagccattta gtggtgcggg atggcgtttt
    20221 ggaggtatgg gtgtaaaacc agctgatggt acaggcaact ttttacgttg gaaatcctac
    20281 attgacgatg gaagagtagg aaatgtaaat caagccaacg caactaaatc tggttctatt
    20341 caaggaatgg cattgtatgc tcgtgaagga ttcaaatact ttgcaccaaa cgggcctggt
    20401 tggacaatga atataggtat ttattacact tataatcctg ttgcaggtac gtattatgtt
    20461 gttcaaaata tttaataaaa cagcacaaag agatttcttt gtgctgtttt attattttta
    20521 gttgttgaca aacactaaaa tataaaatat aatcaacaca taaacgaacg tatgttcggc
    20581 aagaaagcag gggattttta tggatgagat ggttttaagt actcagaaat ggctaaacaa
    20641 gaaatacagt aatgttacag ggtttgataa ggttccagaa aatgggcgaa cagggtggcc
    20701 tacaatctat ggacttattg aaggactaca agtagaactt ggtattacta atctagtagc
    20761 taattttgga cctaccactg aaaaaatgta cgataatcag gttactccta aatggggcaa
    20821 aaatctacct aaaaatattg tatttcttat tcaaggtgcc ttttggtgta aggggattaa
    20881 tccaggtggc ttcgatgggg tatatactcc atatttagat actgctgtaa aagagttgca
    20941 gactgatgca gggtttaatg gaagcgctgt aactggagtt ttggatgcga aatgggccaa
    21001 agcgttattt gatatgagtg cttttgttct tgttcccggc ggagatagta aaattagaaa
    21061 aatgcagcaa tggttaaatg taaattattt agaatacacg ggaataatgc cttgtgatgg
    21121 tatttatcaa agaaattcaa atcaagcatt aatttttgca ttacaagctg aactaggata
    21181 ttctcccagt gaagcaacag ggtcttatgg taatgggaca actagtaaaa cttatcctgt
    21241 gtctgaaggt aactcgggaa actatgtaag aataattcaa tatggattat atgttaatgg
    21301 ttattttgaa gacggtacat tcgatggtat tttcactaaa tatatgggtt tagaagtact
    21361 ggcattccga aaatttatgg tattgcctga atatactgaa atagcagatg ttgttgtaat
    21421 aaaaggactt ttgtctagcg ctggagatat tagaagatct gcagatggcg cagatacttc
    21481 tacgcaatta actagatctc aaatccaaac attggttgat aatgatataa aaatagttgg
    21541 tagatatctt actggtactg ttggaattgg aaaagatgaa cgaaataagt atctaactac
    21601 agaggaattg aataatattt tttctaaaaa tttatctgtg tttcctatct atcaagatgg
    21661 aggtgcagca ttagcttatt ttacttatga tcgtggctta tcagatggta agaaggctat
    21721 agatgcagca aaaaatctaa atataccatt aacaacagtt atttattttg ctgttgatct
    21781 agacatgtta ggggaagaaa ttcttgcata tgctggagaa tattttaagg gggtatctgc
    21841 tgtaatgtca tatagcgggt atcaaacggg tgtttacgga acaagaaatg tttgttctca
    21901 aataatcaat aacgggtatg cttcgtttgc atttgtttca gatatgtcga ctggttatag
    21961 tgggaattta ggttttccta tgcctagaca atggtctttt gatcaatttg ttgaatttac
    22021 cataggaagt ggcaacggag ctgttggtat cgatttaatc gctacatcgg gtagagatag
    22081 cggatttaat gagttatcaa atgatactaa taatgataat tacattgcca aatacaatca
    22141 gaaggttata aatcagatgg tacgtgcgta tcaatatcta tcacaagctg gtcttgataa
    22201 tccttggaac cctcatttga cattttatag atatgtaaat tattctggtt tgtcatggga
    22261 catcatttct tctcctgtaa cagagcatga tagaaaaatt tatgatgaat ataggaataa
    22321 attaactaat agcgagggcc tgtataatta ttttatagat cctaatactg gttcaataat
    22381 aggtttgcct cacttaattg tgacgttaca atcacagatg tttctagccg acacaatcaa
    22441 tgatagtgtt tctgactttg caggttggtt aggagattta atgacttgct ggggtgaagt
    22501 taagaaatta ggaatacaaa tggagcaagg tgtatttgca ttagtaggta cggctgcagg
    22561 tggaacattt agtctagaag atttatacca agatgttgac gcggtaaatg tttatacctt
    22621 agcaaaaaga aattctgatt caacagcttt atcggcttta aaaacgtact attgtgataa
    22681 gggtgctatt gatagattta atcaatttgt taagaacaga tttggttctt cagataaaat
    22741 cgcttcagta acaaatagtt tattagaaaa tgacgaaaca gttgatatct taggtgtagg
    22801 gataatttca tttttcattg ataaaatagt taataattca cttgggacag attttactta
    22861 tcttgatttt attggagatg aggggaaagt tgcaaatgga ttttctgaaa aaattattca
    22921 atttcaagaa aatagaagta aacttaatta agaatcgttt actatttaaa cagtgtcctt
    22981 tt
//
