LOCUS       NZ_CP076489.1          22982 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP076489.1 Enterococcus faecalis strain UAMS_EL56 plasmid
            pUAMSEL1, complete sequence.
ACCESSION   NZ_CP076489
VERSION     NZ_CP076489.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-06-07 17:52:11
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 41639
            Orig. end    :: 64621
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22982
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12982]"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12982
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     cand_cluster    1..22982
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..22982
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     CDS             complement(33..2384)
                     /locus_tag="ctg1_55"
                     /transl_table=11
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQV
                     ELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVYTP
                     YLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLNVNY
                     LEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGNSGNY
                     VRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKGLLSSA
                     GDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTTEELNNI
                     FSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAVDLDMLGE
                     EILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMSTGYSGNLG
                     FPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNYIAKYNQKVI
                     NQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRKIYDEYRNKLT
                     NSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWLGDLMTCWGEVK
                     KLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDSTALSALKTYYCDK
                     GAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFIDKIVNNSLGTDFT
                     YLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     CDS             complement(2509..3198)
                     /locus_tag="ctg1_56"
                     /transl_table=11
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFEE
                     EDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKNDIE
                     TTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFLRWK
                     SYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNPVAGT
                     YYVVQNI"
     CDS             complement(3212..3673)
                     /locus_tag="ctg1_57"
                     /transl_table=11
                     /translation="MRIVKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHN
                     NKKMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSE
                     LVSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     CDS             3795..4475
                     /locus_tag="ctg1_58"
                     /transl_table=11
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRDINVSHT
                     TIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWL
                     RKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLN
                     NLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLL
                     GIPA"
     CDS             complement(4597..5214)
                     /locus_tag="ctg1_59"
                     /transl_table=11
                     /translation="MAKIGYARVSSKEQNLDRQLQALQGVSKVFSDKLSGQSVERPQLQ
                     AMLNYIREGDIVVVTELDRLGRNNKELTELMNAIQQKGATLEVLNLPSMNGIEDENLRR
                     LINNLVIELYKYQAESERKRIKERQAQGIEIAKSKGKFKGRQHKFKENDPRLKHAFDLF
                     LNGCSDKEVEEQTGINRRTFRRYRKRYNVTVDQRKNKGKRDS"
     CDS             complement(5228..5398)
                     /locus_tag="ctg1_60"
                     /transl_table=11
                     /translation="MKKFIYRVLENDEVVAIFNEQQYAQDFIAYEKTISDKQFEIEKVD
                     IADWLLQPREF"
     CDS             complement(5626..6609)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M50"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_61"
                     /sec_met_domain="Peptidase_M50 (E-value: 1.7e-08, bitscore:
                     27.2, seeds: 56, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKFISPMIFTLLLVIFTLVFELNLVSTAYFALLLSIFVHELGHLA
                     FGLFNKVRPESLIFGFIKFSWENQFKIRLNTQWGFFGGLFRYKPTTFNNKKILRLLTGG
                     PIFSLFFTLTFFVKIDFFQYFSLFNFSIFLITAVPFNFNGFMNDGYNIYKLVTKDYIFE
                     MYYIVSNSLLNKYNQSTFLNTTEVCKIIKKNKELPLYVLNTFLLYVIYEYLIDKNNRKL
                     KLIYPILSKEDKILNNKSYLQNFYLANLYMIEYILSVDNKQTFKKINLKILDSISRSRI
                     RYLNFKCSKSDDDEISQSMTEFSNIIKNYSDQMSTMIIAEKQWVQN"
     CDS             complement(6610..7848)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075:alkaline serine protease, subtilase family
                     (Score: 216; E-value: 1.9e-65)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_62"
                     /sec_met_domain="Peptidase_S8 (E-value: 4.8e-37, bitscore:
                     120.9, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKRGLTYILISYIFLILGTTGYASDLSNNISFFIDNSQTTAIEE
                     IESELSSEKVDYIQEIGLVSFKNLDDSDRKFIGKYFNVSEGKKLPDFKPEEVNSSILNI
                     NILNKDFKSFNWPYKKILSHIDPVKEQLGKDITIALIDSGIDRLHPNLQDNNLRLKNYV
                     NDIELDEYGHGTQVAGVIDTIAPRVNLNSYKVMDGTDGNSINMLKAIVDATNDQVDIIN
                     VSLGSYKNMEIDDERFTVEAFRKVVNYARKNNILIVASAGNESRDISTGNEKHIPGGLE
                     SVITVGATKKSGDIADYSNYGSNVSIYGPAGGYGDNYKITGQIDAREMMMTYYPTSLVS
                     PLGKAADFPDGYTLSFGTSLATPEVSAALAAIMSKNVDNSKDSNEVLNTLFENADSFID
                     KNSMLKYKEVRIK"
     CDS             complement(7845..9989)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 240.8; E-value:
                     4.9e-73)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_63"
                     /sec_met_domain="Peptidase_C39 (E-value: 4.5e-43, bitscore:
                     139.5, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRLKYVAQGEHSECALACITMLLNYYGNQSTLVELREKYGVPKG
                     GLTIKNIRTVFDEYGFDVSTFKSSFSNYLDLPTPVISYWNNQHFVVIEKIKKKKVLILD
                     PASNKRWIDISEFKKNFSNILIYAHKKKTKKEGKRKQFFLKSFIFTKFKRYFFSLIILS
                     FVSQLLLLLIPIATKYSIDNIRSFQEIPTYVLLLILTSFFSVLYVVQYLKSSVVAEFQY
                     EFDFKLMFSYIDKLFSMPLMYFSNRSTGELVFRANLNIYIRQILSQKVITTLIDSLFLG
                     IYLFLMVNYSILLTIIALVLISLIAFLSIINSHTIKRFVDKEIMEQGNVQRIITEAIEG
                     IETIKSANAEKSFLLNWKNMFTSQLLITKNKNRYIAIFGILPEIIQSVMPALFLIIGIK
                     LIINNSLSLGSLIGFVSIVTMVMKPILSLVSSYNDFLLLNVYFQKLSEVLTYEEKNDFN
                     NKKGNVGKEEFIYRVNNVYYTISVFEKNILNGISFDIRKGDKVAIVGRSGSGKSTLLKL
                     LAGLLQPSNGEILYEGYPLSNNSNNRRNIFYVNQNAHIFNETIEKNISLEFKPNSSINE
                     KKRLKESMSKSKMDEVLLGIPQYEKTIVSENGSNFSGGQRQKIALARAFYSNVNTLLLD
                     EPTSAMDNISEFEVFSNLLDEKRTVITVAHRISTVKNFDKIILMDNGEIVCIGKHEDLI
                     ENSELYRSLYYKKQQFGGTK"
     CDS             complement(10001..12982)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070:lanthionine synthetase C family protein (Score:
                     844; E-value: 2.6e-255)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_64"
                     /sec_met_domain="DUF4135 (E-value: 8.9e-95, bitscore:
                     311.1, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 2.9e-51, bitscore:
                     167.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEDNLINVLSINERCFLLKQSGNEKYDIKNLQAWKERKSVLKQDD
                     LDYLIKYKYESLDNFGLGITPIENFPDKEVAIQYIKDQSWYIFFESILDSYNDSEEQLL
                     EVDASYPFRYFLQYARLFLLDLNSELNICTKEFIINLLENLTQELIHLTSKTLVLDLHT
                     FKKNEPLKGNDSSKRFIYYLKKRFNSKKDIIAFYTCYPELMRITVVRMRYFLDNTKQML
                     IRVTEDLPSIQNCFNIQSSELNSISESQGDSHSRGNTVSTLTFSDGKKIVYKPKINSEN
                     KLSDFFEFLNKELEADIYIVKKVTRDTYFYEEYIDNIEINNTEEVKKYYERYGKLIGIA
                     FLFNVTDLHYENIIAHGEYPVIIDNETFFQQNIPIEFGNSATVDAKYKYLDSIMVTGLV
                     PYLAMKDKSDSKDEGVNLSALNFKEQSVPFKILKIKNTFTDEMRFEYQTHIMDTAKNTP
                     IMNNEKISFISYEKYIVTGMKSILMKAKDSKKKILAYINNNLQNLIVRNVIRPTQRYAD
                     MLEFSYHPNCFSNAIEREKVLHNMWAYPYKNKKVVHYEFSDLIDGDIPIFYNNISKTSL
                     IASDGCLVEDFYQESALNRCLNKINDLCDKDISIQTVWLEIALNIYNPYKYINDLKNQN
                     SNKYIYTGSELNSKIIQACQKIEKKIFKRAIFNKKTNTVNWIDIKLDQDWNVGILNNNM
                     YDGLPGIFVFYVALKYITKNHKYDYVIECIKNSIYTIPSEDILSAFFGKGSLIYPLLVD
                     YRLNNDINSLNVAVEIADMLIEKKPINNGELKNDWIHGHNSIIKVLLLLSEITEDEKYR
                     KFSLEIFEKLSEEPYFNFRGFGHGIYSYVHLLSKFNRIDKANSLLHKIKESYFEEEPKN
                     NSWCKGTVGELLATIELYDDNISNIDINKTIEYKNKDCLCHGNAGTLEGLIQLAKKDPG
                     TYQYKKNKLISYMLNDFEKNNTLKVAGSEYLESLGFFVGISGVGYELLRNLDSEIPNAL
                     LFEL"
     CDS             complement(13043..13234)
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_65"
                     /transl_table=11
                     /translation="MLNKENQENYYSNKLELVGPSFEELSLEEMEAIQGSGDVQAETTP
                     ACFTIGLGVGALFSAKFC"
     CDS_motif       complement(13127..13234)
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence:
                     MLNKENQENYYSNKLELVGPSFEELSLEEMEAIQGS"
                     /locus_tag="ctg1_65_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(13043..13126)
                     /prepeptide="core"
                     /locus_tag="ctg1_65_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="2.00"
                     /molecular_weight="2632.0"
                     /monoisotopic_mass="2630.3"
                     /core_sequence="GDVQAETTPACFTIGLGVGALFSAKFC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MLNKENQENYYSNKLELVGPSFEELSLEEMEAIQGS"
                     /leader_location="[13126:13234](-)"
                     /alternative_weights="2650.0"
                     /alternative_weights="2668.0"
     CDS             complement(13268..13474)
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_66"
                     /transl_table=11
                     /translation="MENLSVVPSFEELSVEEMEAIQGSGDVQAETTPVCAVAATAAASS
                     AACGWVGGGIFTGVTVVVSLKHC"
     CDS_motif       complement(13403..13474)
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MENLSVVPSFEELSVEEMEAIQGS"
                     /locus_tag="ctg1_66_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(13268..13402)
                     /prepeptide="core"
                     /locus_tag="ctg1_66_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="2.00"
                     /molecular_weight="4019.5"
                     /monoisotopic_mass="4017.0"
                     /core_sequence="GDVQAETTPVCAVAATAAASSAACGWVGGGIFTGVTVVVSLKH
                     C"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MENLSVVPSFEELSVEEMEAIQGS"
                     /leader_location="[13402:13474](-)"
                     /alternative_weights="4037.6"
                     /alternative_weights="4055.6"
                     /alternative_weights="4073.6"
                     /alternative_weights="4091.6"
                     /alternative_weights="4109.6"
     CDS             13878..14078
                     /locus_tag="ctg1_67"
                     /transl_table=11
                     /translation="MIINNLKLIREKKKISQSELAALLEVSRQTINGIEKNKYNPSLQL
                     ALKIAYYLNTPLEDIFQWQPE"
     CDS             complement(14524..15852)
                     /locus_tag="ctg1_68"
                     /transl_table=11
                     /translation="MSLKKMEDRSDIVINKVEKRDILILSSFVFVVMLIYNFGIKQMEF
                     GDDAFFLKQFTHDFQSNYYEFLKFRYNEWTSRLVIEIALTQAVQHVFLWRVLNAIAMSI
                     VAIVPALLFNSDNSRRGLIIGTGMSLLIPASMINNAGWIATTTNYVWVMAAALLSIWPI
                     MNYIRGKSVNWVSLILSLVFLIYATNQEQMVVIMLVSLLILAGILFLSKKNILITLPHI
                     AIVIASLVFILTCKGNAARNVQETKQWLPNFSSYSIFDKLQIGYSSTLKALFFEWSPLM
                     LAFVLLILTAGLVKNGTLVKKMISGIPLLTYLICTRFNTIIDQTYDIVSGKTYMSLVVL
                     LTGLVFLYVIGIFGASNNPLEFLSVIFLLILGVGSRIMMGFSPTIWVSGSRTYYFTYVL
                     IMMSGVYLISQLPENNQSRTFKVLFGYFLVLALLLIMMYTKIL"
     CDS             complement(15961..16824)
                     /locus_tag="ctg1_69"
                     /transl_table=11
                     /translation="MKVKRKKQPYWLGSLLSLVIIGFGLLNHLDLSEQLSSFLSNDIFQ
                     EVAKSDKKSLTKKPRNVKTKKSTSAPYDQQQYNQLANLDFQSGGKAAIEVNNGQSSLDI
                     ATWKENKVIYGDLDSLNRTTFVTAYLDRKNLGRSEGRERQVWQPTGWHQKQIDGDPIVN
                     RGHLLAYTSSFNFDIDGNFKIGENGSQDNPKNLATQTAFSNQKVQTHYEKLVRDAQKLK
                     GNKVIYQIVTVFRGKELMPRGYWLQAIDSAGTLNFNVYEYNVQPNVVFNYEEGTSQIDR
                     TMKVRE"
     CDS             complement(16814..17257)
                     /locus_tag="ctg1_70"
                     /transl_table=11
                     /translation="MREVTAQQLLTEFSIIEKMAQSDAIKQRFCLDNYLAEDVKSAINE
                     LNSLYPAYHFEYQEVFGGFGHDLVVTDIAQKVTYDRIPKTRTYGELFQTLAKVYGIHSS
                     AKFHHKPTDRLTEEEFQETIKFYENFDIDTLFSQDDEDKYDES"
     CDS             complement(17254..17397)
                     /locus_tag="ctg1_71"
                     /transl_table=11
                     /translation="MSNKELSKKYQESLKQRREKQTKRERALEGTVIAPLTDKNNRKDK
                     NK"
     CDS             complement(17471..18406)
                     /locus_tag="ctg1_72"
                     /transl_table=11
                     /translation="MTLTTEVFHDFLCSSQQTFIFQEEKQTKSLVKIMIDPKSTRFFSV
                     FLNPFLQDGESLSFRQNESIGDVIGIYDSVTDTFFSQAEYLIEWHLKGVDITGFKDLHE
                     VIQQLERELAEQTLAEINQHYNYYYTLEGKYLADLSDWKITTLKNEVRKKLLDGQTTFI
                     IDHSFVQYECTDSEILDLLTEKQATQSRLVKKYLEKNARMLSEHLQKLQFQQQYAKELA
                     ENKQFQKEKEIIQAVQKKGMKTITVTYQISDKELTFKMRNIIDSSRDYFSSYDITNKKE
                     RDAYDTLTREAIDLLKIKQISYGRKVLYAE"
     CDS             complement(18547..18744)
                     /locus_tag="ctg1_73"
                     /transl_table=11
                     /translation="MNKEQAFQTLDSLVYAMEKLENESIRSEDNEELEQMLALMNRDWH
                     ELYTIYGKAWEEYRKNALEK"
     CDS             complement(19681..20157)
                     /locus_tag="ctg1_74"
                     /transl_table=11
                     /translation="MIQLSAVGRLTKGAELRTTTNGKSVANVTLACKRKRPDTNGNVST
                     TFIQCVLWGKPAQVFAKYTQKGALVGVNGELQTRSYDDQQGVTHYVTELVVEDFEFLES
                     KETVQKREEKQHAVPQGQSTPTVNEQPAMNQAPTQQNVYQQPSMNGLSEYGYNQ"
     CDS             complement(20297..21631)
                     /locus_tag="ctg1_75"
                     /transl_table=11
                     /translation="MNKKTPKPLTPPKAFFNWCTAQIPTYEWQNKKETILASSRKNCPT
                     IKKRLTKYSRLSFPTKFYSFGIILVRAKRIEIQTHSYWQTITDGTETLIYEPSSLERFS
                     NDTHVKAHYENGHWHEGLLANYGYMSSAYTNTVFYSNNWQEKLTTISELKYLKLPTISR
                     QELAHVYKYRNEIEFLQKIGATTLANEILFDDERNIFGTWHKKVDMRVITKNWLKANKK
                     RLKTTNPTFHMLMLEKTLKERKVARIEGIENYLHYSQIKQLPKEVNLTKFQHWFMRKGE
                     RFSYYMDYLHMLEELNTPFTDDVLFPENLQLAHDNATNTLNLLERELEEQQYQERKKQL
                     KALETEIDDLLFLAPHSLQEIVEEGQVLHHCVGSQHYLEQHTKGKTTIVFIRRKEEPDK
                     PYFTLEYREKRVIQVQGKYNRGHVPEEVEEAIEQWQIEIEKAMPS"
     CDS             complement(21628..22404)
                     /locus_tag="ctg1_76"
                     /transl_table=11
                     /translation="MDFQNIQTVKELRYALKQYKQTLATTIFDDTQGYISVAFKKEVIE
                     KDGKNVQFLCFYPNYEVALYPVETLLAYLEKLPEQAIVTIKDHDGNYSSLFLTIDETID
                     QGNNYQWLVISDKNSYERFFFTAQESTQEQAFEKMLKELETDHDSTLEVVHNWLCRQTD
                     EALFLGILKEDRTLKGAMTYCIGKAQEQSKDQSSAMVADEVVFSWIKEYFLLEKLPETK
                     AVGKVTTTNKKKPTKKSETKPERKEADEQIDLFECV"
     CDS             complement(22566..22832)
                     /locus_tag="ctg1_77"
                     /transl_table=11
                     /translation="MRNRIEELKEQARTELNEWGLIIDGCFEGDFETWIGCYARPKDKP
                     TALDPINEEEAKEQAKYAVNGFPQDFTEWYEWEINNGKLKNLL"
ORIGIN
        1 gaaaaggaca ctgtttaaat agtaaacgat tcttaattaa gtttacttct attttcttga
       61 aattgaataa ttttttcaga aaatccattt gcaactttcc cctcatctcc aataaaatca
      121 agataagtaa aatctgtccc aagtgaatta ttaactattt tatcaatgaa aaatgaaatt
      181 atccctacac ctaagatatc aactgtttcg tcattttcta ataaactatt tgttactgaa
      241 gcgattttat ctgaagaacc aaatctgttc ttaacaaatt gattaaatct atcaatagca
      301 cccttatcac aatagtacgt ttttaaagcc gataaagctg ttgaatcaga atttcttttt
      361 gctaaggtat aaacatttac cgcgtcaaca tcttggtata aatcttctag actaaatgtt
      421 ccacctgcag ccgtacctac taatgcaaat acaccttgct ccatttgtat tcctaatttc
      481 ttaacttcac cccagcaagt cattaaatct cctaaccaac ctgcaaagtc agaaacacta
      541 tcattgattg tgtcggctag aaacatctgt gattgtaacg tcacaattaa gtgaggcaaa
      601 cctattattg aaccagtatt aggatctata aaataattat acaggccctc gctattagtt
      661 aatttattcc tatattcatc ataaattttt ctatcatgct ctgttacagg agaagaaatg
      721 atgtcccatg acaaaccaga ataatttaca tatctataaa atgtcaaatg agggttccaa
      781 ggattatcaa gaccagcttg tgatagatat tgatacgcac gtaccatctg atttataacc
      841 ttctgattgt atttggcaat gtaattatca ttattagtat catttgataa ctcattaaat
      901 ccgctatctc tacccgatgt agcgattaaa tcgataccaa cagctccgtt gccacttcct
      961 atggtaaatt caacaaattg atcaaaagac cattgtctag gcataggaaa acctaaattc
     1021 ccactataac cagtcgacat atctgaaaca aatgcaaacg aagcataccc gttattgatt
     1081 atttgagaac aaacatttct tgttccgtaa acacccgttt gatacccgct atatgacatt
     1141 acagcagata cccccttaaa atattctcca gcatatgcaa gaatttcttc ccctaacatg
     1201 tctagatcaa cagcaaaata aataactgtt gttaatggta tatttagatt ttttgctgca
     1261 tctatagcct tcttaccatc tgataagcca cgatcataag taaaataagc taatgctgca
     1321 cctccatctt gatagatagg aaacacagat aaatttttag aaaaaatatt attcaattcc
     1381 tctgtagtta gatacttatt tcgttcatct tttccaattc caacagtacc agtaagatat
     1441 ctaccaacta tttttatatc attatcaacc aatgtttgga tttgagatct agttaattgc
     1501 gtagaagtat ctgcgccatc tgcagatctt ctaatatctc cagcgctaga caaaagtcct
     1561 tttattacaa caacatctgc tatttcagta tattcaggca ataccataaa ttttcggaat
     1621 gccagtactt ctaaacccat atatttagtg aaaataccat cgaatgtacc gtcttcaaaa
     1681 taaccattaa catataatcc atattgaatt attcttacat agtttcccga gttaccttca
     1741 gacacaggat aagttttact agttgtccca ttaccataag accctgttgc ttcactggga
     1801 gaatatccta gttcagcttg taatgcaaaa attaatgctt gatttgaatt tctttgataa
     1861 ataccatcac aaggcattat tcccgtgtat tctaaataat ttacatttaa ccattgctgc
     1921 atttttctaa ttttactatc tccgccggga acaagaacaa aagcactcat atcaaataac
     1981 gctttggccc atttcgcatc caaaactcca gttacagcgc ttccattaaa ccctgcatca
     2041 gtctgcaact cttttacagc agtatctaaa tatggagtat ataccccatc gaagccacct
     2101 ggattaatcc ccttacacca aaaggcacct tgaataagaa atacaatatt tttaggtaga
     2161 tttttgcccc atttaggagt aacctgatta tcgtacattt tttcagtggt aggtccaaaa
     2221 ttagctacta gattagtaat accaagttct acttgtagtc cttcaataag tccatagatt
     2281 gtaggccacc ctgttcgccc attttctgga accttatcaa accctgtaac attactgtat
     2341 ttcttgttta gccatttctg agtacttaaa accatctcat ccataaaaat cccctgcttt
     2401 cttgccgaac atacgttcgt ttatgtgttg attatatttt atattttagt gtttgtcaac
     2461 aactaaaaat aataaaacag cacaaagaaa tctctttgtg ctgttttatt aaatattttg
     2521 aacaacataa tacgtacctg caacaggatt ataagtgtaa taaataccta tattcattgt
     2581 ccaaccaggc ccgtttggtg caaagtattt gaatccttca cgagcataca atgccattcc
     2641 ttgaatagaa ccagatttag ttgcgttggc ttgatttaca tttcctactc ttccatcgtc
     2701 aatgtaggat ttccaacgta aaaagttgcc tgtaccatca gctggtttta cacccatacc
     2761 tccaaaacgc catcccgcac cactaaatgg ctgtgattta tagcttcctc ctcctgctag
     2821 tacaagaagg tgtccgctag taccaacatc gggtggaaat gctcctcgag gcataattgg
     2881 agtagtttca atatcatttt tgaatttttc agcaacaatt ttttttgctt ctgtcactga
     2941 aactgaagca ggatcagttt ctgaattata tgaaccttga attatatctg gattatccat
     3001 agatacaatt ttagcttccc cttttaaaaa accaccttct ggcaatgcaa gtactttatc
     3061 ttcttcttca aaatcagcaa agtatcgtga ggcgtactgc tctggatctg aaataacttc
     3121 tttctcagca gcatatactg catttccaaa tgttaacatc ataagtagcc caacagaaac
     3181 accaaaaatc tttttcataa tgaatcttcc tttactctaa ttccactgaa ttagtttctt
     3241 ttatctgctt taattcattt cttttactat ttaaaagctc ttttagatcc ttaatcgaaa
     3301 tagcgttgga atcagtatta acatcaataa actgtctgtg attttgttta taactaacta
     3361 attcggattt gccatctccc attaattgcc caccagcaga caagacaaca attttatctg
     3421 agtcactaat tcctggaata ctttcttcta actgttcccc ggataaatca ccaaattctt
     3481 tatacaattc ttcatctgac atagaataga tatttttggt caaactcatt tttttattat
     3541 tatgttcagc tactctttga tcttttattt gagcgtttga attaacagaa tctaaattca
     3601 aaagaaaata gcccccaatt aatattgtaa atactgaaaa aatacttagt atcgtttttt
     3661 tcacgattct cacctcgctt tcttattaaa tttataatat atatctacga taagataatt
     3721 ggttctgttg caaagtttta aatctactat caaataagat agaataatag aaaaagatag
     3781 caggaggaat aacgatgaat cattttaaag gaaagcaatt tcagcaggat gtgattattg
     3841 tagccgtggg ctactatctt cgttataacc ttagctatcg tgaagttcaa gaaatcttat
     3901 atgatcgtga cattaacgtt tctcatacga cgatttatcg ttgggtgcaa gaatatggca
     3961 aactactcta tcaaatttgg aaaaagaaaa ataaaaaatc cttttattca tggaaaatgg
     4021 atgaaacgta catcaaaatt aaaggaaaat ggcattattt gtatcgagcc atcgatgcag
     4081 atggtttaac cttggatatt tggttacgta aaaaacggga cacacaagca gcctatgctt
     4141 ttcttaagcg gttagtgaag cagtttgatg aaccgaaggt tgtagtcaca gataaagccc
     4201 cctctattac aagtgccttt aagaaactaa aagaatacgg cttttatcaa gggacagaac
     4261 atcgtaccat taaatacctg aataatttga ttgaacaaga ccatcgtcca gtaaagagac
     4321 gcaataaatt ctatcgaagt ttacgcactg cctctaccac gattaaaggc atggaagcca
     4381 ttcgaggatt atataagaaa acccgaaaag aaggcactct cttcgggttt tcggtctgta
     4441 ctgaaatcaa ggtattattg ggaatcccag cttaaatcat agataccgta agggatttta
     4501 ttctttattt aaaactttgc aacagaaccc tctgattaaa tgcctgggca taggctaacg
     4561 cctggcttgg tttttcagct aaaataactg tactcattaa ctatccctct ttcccttgtt
     4621 ttttctttga tcgactgtca cgttatatct tttacgatac cttctaaacg ttctgcgatt
     4681 aattccagtt tgttcctcaa cttctttatc ggaacaaccg ttcaaaaata aatcaaaagc
     4741 atgttttaaa cgtggatcat tttctttaaa tttatgctga cgacctttga attttccttt
     4801 tgacttagct atttcaatcc cttgggcttg tcgttcttta atacgtttgc gttctgattc
     4861 cgcttgatac ttatataatt caatcactaa attattaatc aaacgcctta aattttcatc
     4921 ttcaatccca ttcatagagg gcaaattcaa aacttcaagc gttgctcctt tttgttgaat
     4981 ggcattcatc aattctgtta attctttatt attccgtcct aatcgatcta attcagtaac
     5041 tacaacaata tccccttcac gaatatagtt aagcatagct tgtaattgtg gacgttcgac
     5101 cgattgaccg cttaatttgt ctgaaaagac cttagaaacg ccctgtaacg cttgtaattg
     5161 ccgatctaag ttctgttctt tgctactgac acgtgcataa ccaattttag ccattttcaa
     5221 ccaacctcta aaattctctc ggttgcaata accaatcagc tatatctact ttttcaattt
     5281 caaattgctt atcagaaatt gtcttttcgt aagcgataaa atcttgcgca tattgttgtt
     5341 cattaaaaat agccaccact tcgtcatttt ctaaaactcg ataaataaat tttttcattt
     5401 tactcctcct attatgctca acttaaatga cctattcacc aagtcaatta tactgctaaa
     5461 atcatattag gacaaataag tataccctgt tggttctttt agttaatata ttttaacaga
     5521 aaatttattt attacatcat gaaatactgt ataaaaatcg tagcaagcac acatcacttt
     5581 tgttagccta tcattttacg tcgacagtct agctggtttc ttatctcaat tttgaaccca
     5641 ttgtttttct gctataatca tagtcgacat ttgatctgaa taatttttta tgatattgct
     5701 aaattctgtc attgattggc ttatttcatc atcatcactt tttgagcatt taaagtttag
     5761 atatctaatt ctagatctac taattgagtc tagaattttt aaatttattt ttttaaaagt
     5821 ttgtttatta tctacagata agatatattc tatcatatac aaattagcca aataaaaatt
     5881 ctgtaaataa cttttattat tcagtatctt gtcttcttta ctaagtattg ggtatattag
     5941 ttttaatttc ctattatttt tgtctattaa atactcatat ataacataca ataagaatgt
     6001 atttagcaca tataatggta attctttatt tttttttatt attttgcata cctcagttgt
     6061 atttaagaaa gttgactgat tatatttatt aagtaagcta tttgatacaa tataatacat
     6121 ttcaaaaata taatccttag taactaattt atatatattg tatccatcat tcataaaccc
     6181 gttaaaatta aaaggaactg cagtaattaa aaatatcgaa aaattaaata aagaaaaata
     6241 ttgaaaaaag tcaattttta caaaaaaggt taatgtaaaa aaaagactaa atattggtcc
     6301 cccggttaac aacctcagaa ttttcttatt attaaacgta gttggtttat atctaaataa
     6361 tccaccaaaa aatccccact gtgtatttaa tctgatctta aactgatttt cccacgaaaa
     6421 ttttataaac ccaaatatta atgactctgg tctaacttta ttaaataatc caaaagctaa
     6481 gtgccctaac tcatgtacaa agatagacaa taacaaggca aagtatgctg tagacactaa
     6541 atttaattca aaaacaagag taaagattac gagaagtaac gtaaagatca tcggagatat
     6601 aaatttcatc tattttattc tcacctcttt gtatttaagc atgctatttt tatctataaa
     6661 agaatcagca ttttcaaata aagtatttaa tacttcattt gaatctttag aattatctac
     6721 attctttgac ataatagctg ctaaagctgc gcttacttct ggagttgcta aacttgttcc
     6781 aaaagaaagt gtataaccat ctggaaagtc agcagctttg cctagtggag aaactagcga
     6841 tgtagggtaa taagtcatca tcatttcacg agcatcaatt tgtcctgtta ttttgtaatt
     6901 gtcaccatat cctcctgcgg gaccatatat agatacatta gacccataat tagaatagtc
     6961 agcaatatca ccactctttt ttgtagctcc gacggtaatt acagactcta gtcctcctgg
     7021 tatatgtttt tcattaccag tgcttatatc acgcgactca tttcctgctg atgcaacaat
     7081 tagaatgtta ttttttcttg catagttaac aacttttctg aatgcttcta cagtaaatct
     7141 ttcgtcatct atttccatat ttttatatga tccaagactc acatttatta tatctacttg
     7201 atcatttgta gcatcaacta tagctttaag catatttata gagtttccat ctgtcccatc
     7261 catcaccttg taagaattta aattcactct tggagcaatc gtgtctatta ctccagcaac
     7321 ttgtgtacca tgaccatatt catctaactc aatatcatta acatagtttt ttaatcttag
     7381 gttattgtct tgaagattag gatgaagcct atcaatcccc gagtcaatta gagctatggt
     7441 tatatctttc cctagttgtt ctttcactgg atcaatatga gataaaattt ttttatatgg
     7501 ccaattaaaa gacttaaaat ctttgtttaa aatattaatg tttaaaatag aactattaac
     7561 ttcttcaggt ttaaaatctg gtaatttttt cccttccgaa acattaaaat atttacctat
     7621 aaacttccta tcactatcat ccaggttttt aaaactaact aatcctattt cctgtatata
     7681 atctactttt tcagaagata attcagactc aatttcttct atagcagttg tttgcgaatt
     7741 atcaataaaa aatgaaatat tatttgagag atctgatgca taacctgttg ttcctaatat
     7801 taaaaaaata tatgagatta aaatataagt caatcctctt tttttcattt tgtacctcca
     7861 aattgttgtt ttttgtaata cagtgaacga tataactcgc tattttcaat aagatcttca
     7921 tgctttccaa tacatactat ttcaccatta tccattaata taattttatc aaagtttttc
     7981 acggtactaa ttctgtgagc aacagtaata actgttcttt tctcatctaa taaattagaa
     8041 aaaacttcaa attctgaaat attatccatt gcagatgtag gctcatctaa aagtaatgta
     8101 ttcacattag aatagaacgc tctagctaaa gcaatctttt gcctttgacc accagagaaa
     8161 ttactaccat tttctgatac tatagttttc tcatactgag gaattcctaa aagtacctca
     8221 tccatttttg atttactcat actttctttt agtctttttt tctcatttat agaagaattc
     8281 ggtttaaact ctaaagaaat atttttttcg atagtttcat taaaaatatg cgcattttga
     8341 ttaacataaa aaatgtttct tctattattg gagttgtttg ataaaggata gccttcatac
     8401 aatatttctc cattagaagg ttgtaacaat ccagccaata gttttagtaa agtagatttc
     8461 cctgacccac ttctaccaac aatagcaact ttatcccctt ttcttatgtc aaaagaaata
     8521 ccatttaaaa tatttttttc aaaaacagat atagtatagt aaacattatt aaccctataa
     8581 ataaactctt cttttccaac atttcctttt ttattattaa aatcattttt ttcttcataa
     8641 gttaaaactt cagataattt ttgaaaatat acatttaata gtagaaagtc attataagag
     8701 gaaaccaaac ttagaattgg cttcataacc attgttacta tagaaacaaa accaattagt
     8761 gatcctaatg acaaagaatt gttgattatt aatttaatac ctattattaa aaatagagct
     8821 ggcattacac tttgtatgat ttctggtaat attccaaaaa tagctatata tctattttta
     8881 ttttttgtaa ttaatagttg agacgtaaac atgtttttcc aatttaacaa aaaactcttt
     8941 tctgcattag cagatttaat ggtttcaatt ccttcaattg cttctgtaat aattctctgg
     9001 acgtttcctt gttccattat ttctttatct acaaatcttt ttattgtatg cgaatttata
     9061 atacttaaaa aagctattaa agagattaga acaagagcta ttattgtcag taaaatagaa
     9121 tagttaacca ttaaaaacaa atatatccct aaaaaaagac tatctattaa agttgttatt
     9181 accttttgag acaatatttg cctaatataa atatttaagt tcgctctaaa cactaattct
     9241 ccagttgatc tattactaaa atacattagt ggcatactaa aaagtttatc aatataagaa
     9301 aacattaatt taaaatcaaa ttcatactga aattctgcta ctacagagct ttttaagtat
     9361 tgaactacat ataaaacaga aaaaaaacta gttaatatta ataacagaac ataggtagga
     9421 atttcttgaa aagatctaat attatctatc gaatactttg ttgcaatagg aattaagagt
     9481 aataaaagtt gtgaaacaaa tgataatatt attaaactaa agaaatatct tttgaatttt
     9541 gtaaaaataa atgactttaa aaaaaactgt ttccttttgc cttctttttt agtctttttc
     9601 ttatgtgcgt atattaatat atttgaaaaa ttttttttga attctgaaat atcaatccag
     9661 cgtttattac ttgcaggatc taagattaat actttcttct tttttatttt ctctatgacc
     9721 acaaaatgtt gattattcca ataacttatt acaggagtcg gaagatctaa ataatttgaa
     9781 aaacttgatt taaatgtcga tacatcaaat ccatattcgt caaagacagt acgaatattc
     9841 ttgatagtta gtcctccttt gggcacccca tatttttccc ttagttctac tagtgtactt
     9901 tgattaccat aataattaag tagcatagtg atacatgcca aagcacattc actatgctct
     9961 ccttgcgcaa cgtacttcaa tcttttcata attacacctc ttataactca aaaagtaatg
    10021 cattcggaat ttcagaatct aggtttctca ataattcata acccacacca ctgattccta
    10081 caaagaatcc tagtgattct aaatactcac ttccggcaac ctttagtgta ttattttttt
    10141 caaaatcatt taacatatag ctaataagtt tatttttttt atactgataa gttccaggat
    10201 cttttttagc taattgaatt agaccttcta aagtacctgc atttccatgg cacagacaat
    10261 ctttattttt atattctatg gttttattaa tatctatatt tgaaatgtta tcatcatata
    10321 attcaattgt cgctaaaagt tcacctacag ttcccttaca ccaactattg tttttaggtt
    10381 cttcttcaaa gtatgattct ttaattttat gaagtaaaga atttgcctta tctatcctat
    10441 tgaattttga tagaagatgg acatagctat atataccgtg tccgaatcct ctgaaattaa
    10501 aatagggttc ttcggataat ttttcaaaaa tttctaatga aaattttcta tatttttcat
    10561 cctctgttat ctcggataac aataataaaa cttttattat actattatgc ccgtggatcc
    10621 aatcattttt taactcgcca ttatttatcg gtttcttttc aatcaacatg tctgcaattt
    10681 ctacggctac atttaaagag tttatatcat tatttaagcg gtaatctaca agtaaaggat
    10741 atattaaact tccttttcca aaaaaagctg acaatatatc ttcagatggt attgtataaa
    10801 ttgaattttt tatacattca attacataat catatttatg attctttgta atgtatttaa
    10861 gagccacata aaatacgaat ataccaggca atccatcgta catattatta tttaggatgc
    10921 ccacattcca atcttgatcc aattttatgt caatccaatt tacagtattg gtttttttat
    10981 taaaaatagc tctcttgaaa atttttttct ctatcttctg acatgcttga ataattttac
    11041 tatttagctc tgagccagta taaatatatt tatttgaatt ttgatttttc aaatcattaa
    11101 tatatttata tggattataa atattcaaag caatttctag ccaaacggtt tgaatagaaa
    11161 tatctttatc acaaagatca tttattttat ttaggcatct attcaaagca ctttcttgat
    11221 aaaaatcttc tactaagcac ccgtcactag ctattaatga tgtttttgag atattgttat
    11281 aaaaaatagg tatatcccca tctattaagt ctgaaaattc gtaatgaaca accttcttat
    11341 tcttatatgg ataggcccac atattatgaa gtactttttc tctctctatt gcattagaaa
    11401 agcaattagg atggtatgaa aattccaaca tatcagcata tctttgagtt ggtctgatta
    11461 catttctaac tataagattt tgtaaattat tattaatata tgccaatatt tttttcttag
    11521 aatcctttgc tttcattaaa atacttttca taccagtaac tatatatttt tcatagctga
    11581 taaaactaat tttttcatta ttcataattg gagtattttt tgcagtatcc ataatgtgtg
    11641 tttgatattc aaaacgcatt tcatcagtaa atgtattttt aatttttaat atcttgaacg
    11701 gtacgctttg ctctttaaag tttaacgcac taaggttaac cccttcatct ttcgaatctg
    11761 acttatcttt catcgctaaa tatggtacta gccctgtcac cattatagaa tctaaatatt
    11821 tatatttagc atctactgtt gcgctattac caaactctat aggaatattt tgttgaaaaa
    11881 aagtttcgtt atctatgata acagggtatt ctccatgagc gattatattc tcatagtgta
    11941 agtctgttac attaaataag aaagctattc cgattagttt accatacctt tcataatatt
    12001 tttttacttc ttctgtgtta tttatttcta tattatctat atattcttca tagaaatagg
    12061 tatctctagt aactttttta actatataaa tatctgcctc taattcttta tttaaaaatt
    12121 caaaaaaatc gcttaattta ttctcgctat taatctttgg cttgtatact atcttctttc
    12181 catccgaaaa agttagtgta gaaacagtat ttccgcgact atgagagtct ccctgtgatt
    12241 ctgatataga gttaagctct gaggattgta tgttaaaaca attttgtatg ctaggtaaat
    12301 cttcagtcac tcttataagc atttgtttag tattatctaa aaaatatctc attctaacaa
    12361 cagtaatacg catcaactca ggatagcatg tataaaaagc tattatatct tttttagagt
    12421 taaatctttt ttttagataa tagataaatc gcttgctact atcatttccc tttagaggtt
    12481 catttttttt aaaagtatgc aaatctagca ctaatgtttt acttgtcaag tgaataagct
    12541 cttgtgttag attttctaat aaattaataa tgaattcttt tgtacaaata tttaactctg
    12601 agtttaaatc aagtaaaaat aaacgagcat attgtaagaa atatctaaaa ggataactag
    12661 catctacttc taataattgc tcttcactat cattataaga atctaaaatg gattcaaaaa
    12721 aaatatacca tgattgatct ttaatgtatt gaattgcaac ttctttatca ggaaagtttt
    12781 caataggtgt tattcctaat ccaaaattat ccagtgattc atatttatat ttaatcaagt
    12841 agtctaaatc atcttgttta agaacacttt ttctttcttt ccaagcttgt aaatttttaa
    12901 tgtcgtactt ctcgttacca ctttgcttta gtaaaaagca tctttcattt atgcttaaaa
    12961 catttattaa attatcttcc atgtaagcac tcctttttta tgtataagag ggctagtttc
    13021 actagccctc ttaatatata aattagcaaa atttagctga aaataatgca cctactccta
    13081 agcctatggt aaaacatgct ggagttgtct cagcctgaac atctccacta ccttgaatcg
    13141 cttccatttc ttctaaactt aactcttcaa aagaaggacc aacaagttct aatttattag
    13201 agtaatagtt ttcttgattt tccttattta gcactgtgct tcacctcact aagttttata
    13261 gtatatttta acaatgtttt aaagacacaa ctacagttac tccagtaaaa ataccgccac
    13321 caacccagcc acaagcagca ctacttgctg cagctgtcgc cgcaacagca cacaccggtg
    13381 ttgtctcagc ctgaacatct ccactacctt gaatcgcttc catttcctca acacttagtt
    13441 cttcaaaact aggaactaca cttaaatttt ccataattct taccctccat cataaaattg
    13501 ttgtatattg cataacataa tatgttacaa tttaatatta tagagctttt aatcttttgt
    13561 caagtgtcac ttgacaaaaa ggaggaacca aaatggctat ttttattttt ttattggata
    13621 tcatttctgt agtctacttt gtttttaatc tgactgattc aaaaaaagat gagcgaattt
    13681 tatatacaat ttccttaaca tctacttaca tgtacttatt tattaacttt tccatactta
    13741 tagtagttgc tatttttctt tttctaccta atgttattac taaaaactat ctctttaatt
    13801 ttatctacta ttacttctct ctatcaatga tattgcactc tctgttacta ctttttttca
    13861 acaagaggac ttcataaatg ataatcaata acttaaaatt aattagagag aaaaaaaaaa
    13921 ttagccaaag tgaattagct gctttattag aagttagcag acaaactatt aatggtatag
    13981 aaaaaaataa atataaccct tctttacagt tagcattaaa aattgcttac tacctgaata
    14041 ctccactaga agatattttt caatggcaac ctgaataaaa aagattttta aatttcacca
    14101 cagaatattt aaattaaaag aaaggtgctt cgtatgaaga aaaagtttat atcccttctg
    14161 attttatttt taggaataat tgttggcata gtaacagttt atattttaaa gcataaataa
    14221 ttatgactgt tgttttatac tttaatcata actgattttt tatcagtaaa accctcactt
    14281 atgattacat tcatttaaat aaaaactagg ctcaaatgta tagtaaagac tatctctttt
    14341 tggggggaga cagtctctaa ggttataact tattttagcc tttcatttct aacgcatact
    14401 catagaacta aatgattgat taattcagtc tgtaagaaaa tagttaaatc tgaagtgact
    14461 tgtaattatt ctacagtata cacactgtcc tttcaacaac tgtcgaaagt ttagcaaaac
    14521 attttacaat atttttgtat acatcattat taataataga gccaatacca gaaaatatcc
    14581 gaatagcact ttaaaggttc tactttggtt attttcaggt agctgactta ttaaatagac
    14641 acctgacatc attataagaa cataagtgaa atagtaagtc cttgatccag atacccatat
    14701 ggtaggagag aaccccatca taatacgact tcctacaccc aaaataagaa gaaagataac
    14761 tgataaaaat tctaagggat tattacttgc cccaaaaatc cctattacat aaagaaaaac
    14821 caacccagta agaagaacta ctagtgacat atatgttttt cctgaaacta tatcataagt
    14881 ttgatcaata atcgtattaa atcttgtaca aatcaaatac gtcaatagcg gtattccact
    14941 aatcatcttt ttgactaatg tcccattttt tactagtcca gcagtaagaa ttagcaatac
    15001 aaaagctaac atcaatggag accactcaaa aaataaagct ttcaaagtgg acgaataccc
    15061 tatttgtaac ttatcaaaaa tactgtagct agaaaaatta ggtaaccatt gtttcgtttc
    15121 ttggacgttt cttgccgcat tccccttaca tgttaaaata aacacaaggc tagcgattac
    15181 aatagcaata tgaggtaaag ttatcaggat attcttttta gacaaaaata gaatacccgc
    15241 taaaattaat aaagaaacta acataatgac taccatttgt tcttgatttg tagcataaat
    15301 caagaacacc aacgataaaa taagagatac ccaatttaca ctttttcctc ttatatagtt
    15361 cataataggc caaatactta acaacgctgc tgccatgacc caaacataat ttgttgttgt
    15421 tgctatccat cctgcattat ttatcatcga agcaggaatt aataatgaca tgccagtacc
    15481 tataattaat cctcttcgac tattatctga gttaaacagt agtgcaggga caattgccac
    15541 tatagacatt gctatagcat ttaaaactct ccacaaaaat acgtgttgta ccgcttgtgt
    15601 tagagctatt tcaatcacta atcgagacgt ccattcattg tacctaaact tcaaaaattc
    15661 ataatagtta ctttgaaaat catgtgtaaa ctgctttaag aaaaacgcat cgtccccaaa
    15721 ttccatttgt ttaataccaa aattgtaaat taacattacc acaaatacaa aactactgag
    15781 aattaaaata tctctctttt ccactttatt tatcactatg tcactcctat cctccatttt
    15841 tttcaaggac atgcgcttta taaatactat cgatactaga cattggaagc ttttctaatt
    15901 cttcatacgt aaagtcacta ttacgtacaa tcaatattat tttttcttct ttagtcattg
    15961 ctactccctc actttcattg ttctatcgat ttggcttgta ccctcttcat aattgaacac
    16021 gacgtttggc tgcacattat attcataaac attgaaattc agtgtacccg cactgtcaat
    16081 cgcttgtaac caataacctc gaggcattaa ttcctttcca cgaaaaactg tcacgatctg
    16141 ataaatgact ttgttcccct taagcttttg tgcatctctg actagtttct catagtgcgt
    16201 ctgcactttt tgattagaaa aagctgtttg tgttgccagg tttttgggat tgtcttggct
    16261 tccattttca cctatcttaa agtttccgtc aatatcaaag ttaaagctgg acgtatatgc
    16321 aagtaaatgt ccgcgattca caatcggatc tccatcgatc tgtttttggt gccaaccagt
    16381 cggttgccag acttgccgtt ctcgtccttc agaacgtcct aaattcttcc tatcaaggta
    16441 ggcagtcaca aatgttgtcc ggttcaaaga atctaagtct ccataaatca ctttgttttc
    16501 tttccacgtg gcaatatcta aactagattg tccgttattg acctctatag cggcttttcc
    16561 gccactttga aagtctaggt tagctaattg attatattgt tgctgatcgt atggcgcact
    16621 tgtggatttc tttgttttta catttcttgg tttctttgta agtgactttt tatctgattt
    16681 cgccacttct tgaaatatat cattagataa aaaagacgag agctgctctg ataagtctaa
    16741 atgattcaac aatccaaaac caattatcac caaggacaat agactaccta accaataggg
    16801 ctgttttttt cttttaactt tcatcgtatt tgtcctcatc atcttgactg aataatgtat
    16861 ctatatcaaa gttttcatag aacttgattg tttcttgaaa ttcttcctca gttaatcgat
    16921 ctgttggttt atgatgaaat tttgcacttg agtgaatccc gtaaaccttt gctagtgttt
    16981 gaaaaagttc gccataagta cgtgttttag ggatacgatc gtatgttact ttttgcgcaa
    17041 tatcggtaac gactaaatca tgaccgaatc caccaaatac ttcttggtat tcaaaatggt
    17101 atgctggata taaactgttc aattcattaa tagcagattt cacatcttct gctagatagt
    17161 tatccaaaca aaaacgttgt ttaatggcgt ctgattgcgc cattttttct attatggaaa
    17221 attctgttaa aagttgttgt gccgttactt ctctcatttg tttttgtcct ttcgattatt
    17281 tttatcggtg agtggggcaa taactgttcc ttctaacgca cgttcccgtt ttgtttgctt
    17341 ttctcggcgt tgtttcaaac tttcttgata ctttttgctt aattctttat tagacatttt
    17401 tcgcttctcc tttacaattc ctaagagtag aaattttcta ctcttaggac cccttttgat
    17461 ttagttgttt ttactctgca tataaaactt ttcgtccgta gctaatttgc ttaattttta
    17521 gtaaatcaat agcttcacgc gtcaatgtat cataggcgtc acgttccttt ttgttggtaa
    17581 tatcgtaact cgagaagtaa tcacgactgc tatctatgat gtttctcatc ttgaatgtca
    17641 gttccttatc tgaaatttgg tacgtcaccg taatggtttt cattcctttc ttctgcactg
    17701 cttgaataat ttccttttct ttttggaatt gtttattctc tgctaattct tttgcatact
    17761 gttgttggaa ctgtagtttt tgtaagtgtt cagacaacat ccttgcattt ttctctaaat
    17821 atttttttac taatcgtgat tgtgtagctt gtttctccgt tagtaagtct agtatctcac
    17881 tgtctgtgca ttcgtactga acaaacgaat gatctataat gaacgtagtt tgcccatcga
    17941 gtagtttttt tcgcacttca ttttttagtg ttgttatttt ccaatctgat aagtccgcta
    18001 gatactttcc ttccagtgtg taatagtagt tgtagtgttg attgatttca gcaagcgttt
    18061 gttctgccag ttctctttcc agctgttgaa tcacttcgtg aagatcttta aaacctgtta
    18121 tatctacacc ctttaaatgc cattcaatca aatactctgc ttgtgaaaag aatgtatctg
    18181 tcacgctgtc atatatgccg ataacgtctc ctattgactc attttgccga aaggaaaggg
    18241 actctccgtc ctgtaaaaag ggattcaaaa agacggagaa aaagcgggta cttttcgggt
    18301 cgatcattat cttaaccagc gactttgtct gtttttcctc ttgaaaaata aaggtttgtt
    18361 ggctgctaca taaaaagtca tgaaatactt cggttgttag tgtcataatt cttacctgct
    18421 ttctcttttt gatttttttt gtacttgtca aagaaacgta ggtaagttat acttaaaatc
    18481 tatagtttgt taaatataac taccttttta gaaatctttt gtcgtaagca aaaggtttct
    18541 ttttttttac ttttcaaggg cgttcttccg atattcttcc catgcttttc cataaatggt
    18601 atagagttcg tgccaatctc tgttcattaa tgccaacatt tgctctaatt cttcgttatc
    18661 ctccgagcgg atactctcgt tctctagttt ttccatggcg taaacaagtg aatctaatgt
    18721 ctgaaaggct tgttctttgt tcatttggtt ttccttcttt cggttttgat ttttgaacaa
    18781 ccatttttgt taggcgtttg aggaagtgaa gctggacggt caaaaatttc ttttcgtcaa
    18841 acggtgtagt ctccccccct ttttcgtttt cgattaggtt gttcattttc gccagtgtgt
    18901 tcgtgtcgtt cgctgtgccg agaaaggacc gtagacataa agaaaaaaca agggcgagct
    18961 tgctcgttta tatacccttg ttttttcgac tggctatggt actgtaacaa acagtgaaca
    19021 gcacgttaca cacggcaaaa ggaacggcct gaaaacgaaa aaggctgcgt gacaccgttc
    19081 tgacatcaga aaagaaattt ttgaccggaa tgttcttgac ctttgccttg tgaaacaagg
    19141 ctttcttccg aacggcggtg gcggttggag taaggaagaa acagctcttt tctcttgatt
    19201 cttctttatg taaaaagcct tgtattgcaa gcaatacaag gctttttatg ctataataga
    19261 attgatagta aagtttaatg acggtggcta tccaatcgaa agtgaggtgg tgcgtatgaa
    19321 cgtacttcca aaatctatag aaaggagaag ccttttgtcc gtttcggaaa gtttgcaact
    19381 aatgcttgcg tttggtgggt ttacattgac cctaatcaca accattgttg ccattctgaa
    19441 ctataaagac aaaaagaaat aaccgtcact ttagcaggag accggttatt tctaaataac
    19501 ttataaaaac tctgccaccg tctttagcgg tgctatcaat gagggcgtat taccagtacg
    19561 tcctctttac ataattatta taccacattt tgtgcgaaaa ggtaggcgaa tgcctacctt
    19621 ttttcatgcg cgcctaaacg gcggtggcgg tgggagtgtg gcgcgcatga aaaaacagat
    19681 ctattgattg tagccatatt cagacaaccc gttcatggac ggttgttggt agacattttg
    19741 ttgtgttggt gcttgattca ttgctggttg ttcattaacc gttggggttg attgtccttg
    19801 tgggactgcg tgttgttttt cttctcgttt ttgtacggtt tctttggact ctaaaaactc
    19861 aaaatcttct acaactaatt ctgtcacata atgcgtaacg ccttgttggt catcatacga
    19921 acgagtttgt agttccccat ttacaccaac taatgcgcct ttttgcgtgt attttgcaaa
    19981 gacttgggcg ggtttgcccc ataaaacaca ttgaataaat gtggtcgaca catttccgtt
    20041 agtgtctggt ctttttcgct tacaagccaa tgtaacgttt gcgacactct ttccgttagt
    20101 ggtggtacgt agttcggctc cttttgttaa acgcccgaca gctgataatt gaatcatgat
    20161 tgtttccttc tttctgattt tttatttata tcatgccttt tttagtggca ataaatatct
    20221 tgttaagtgg aagttttttt gaaatgagag tgatttgcct gtctaggcaa atcacctcct
    20281 tctatctgcc atgcccttat gagggcatgg ctttttcaat ctctatttgc cattgttcaa
    20341 tggcttcttc tacttcttct ggtacgtgtc cccgattgta tttcccttgc acttgtatca
    20401 ctcttttttc acggtattct aaggtaaaat atggtttatc tggttcttct tttcttcgga
    20461 taaaaacaat cgttgttttt ccttttgtat gttgttcaag gtaatgttgg ctaccaacac
    20521 aatggtgcaa tacctgccct tcctccacaa tttcttgcaa cgaatgtggg gcgagaaaaa
    20581 gtaagtcgtc aatttcggtt tctaatgctt tcagttgttt ttttcgttct tggtattgct
    20641 gttcttcaag ctctctttca agtaaattca acgtatttgt ggcattgtca tgggctagtt
    20701 gcaagttttc agggaaaagc acatcatcag taaatggtgt attcagttcc tctagcatgt
    20761 gtaaatagtc catatagtag ctaaaacgct cgccttttcg cataaaccag tgttgaaact
    20821 tggttaagtt cacttcttta ggtaattgct taatttgtga ataatgtaaa taattttcaa
    20881 ttccttctat tctcgcaact tttcgctcct tcaaagtttt ttctagcata agcatatgaa
    20941 acgttgggtt ggtggttttt agtcgctttt tattggcttt tagccagttc ttagtaataa
    21001 ctctcatgtc tactttttta tgccatgtgc caaaaatatt gcgttcatca tcaaaaagta
    21061 tttcgtttgc cagtgtcgtt gcacctattt tttgtaaaaa ttcaatttca ttgcggtatt
    21121 tataaacatg cgccagttct tggcgactaa ttgtaggtag cttgaggtat ttcaattccg
    21181 aaatggtcgt tagtttttct tgccagttat ttgaatagaa aacagtgttc gtgtaagcac
    21241 tactcatgta accataattt gctaacaagc cctcatgcca gtgtccgttt tcataatgtg
    21301 ctttaacatg ggtatcgttt gaaaaccgtt caaggcttga cggctcatag ataagggttt
    21361 ctgttccatc tgtaatcgtc tgccaataac tatgggtttg aatttcaatt cgttttgcac
    21421 gaacgagaat gattccaaag gagtaaaatt tcgttggaaa cgataatcgt gagtatttcg
    21481 ttaatcgttt ttttatggtg gggcaattct tgcgagaact cgcaagaatt gtctcctttt
    21541 tgttttgcca ttcatacgtt ggtatttgtg cagtacacca gttaaaaaag gctttgggtg
    21601 gggttaatgg ttttggtgtt tttttattca tacgcactcg aacaaatcaa tttgttcgtc
    21661 cgcctctttt ctttcaggtt ttgtttctga ttttttggtc ggtttctttt tgtttgtggt
    21721 cgttacttta ccaactgctt tggtttctgg taatttctct aataagaaat actcttttat
    21781 ccaactgaaa accacttcgt ccgccaccat ggcgcttgat tggtctttgg attgttcttg
    21841 ggcttttcct atgcagtaag tcatagcacc ttttaacgtt ctatcttctt tgagaatacc
    21901 tagaaaaagc gcttcgtctg tttgtcggca taaccagtta tgaacaactt ctagtgtact
    21961 gtcatggtcg gtttctagtt cttttaacat tttctcaaaa gcttgttctt gcgtgctttc
    22021 ttgagctgta aagaaaaatc gttcgtaaga atttttgtcg ctaatcacta gccattggta
    22081 gttgtttcct tggtctatcg tttcgtcaat tgttagaaaa agtgacgagt agttaccgtc
    22141 atggtcttta atcgtaacga ttgcttgttc aggtaacttt tcaaggtaag ccagtaacgt
    22201 ttctactgga taaagagcta cctcataatt tggataaaaa cataaaaact gaacgttttt
    22261 tccgtctttt tctatcactt cttttttaaa ggcgacactg atatagcctt gtgtatcatc
    22321 aaaaatcgta gttgcgagtg tttgtttgta ttgtttcagt gcgtatctta attcttttac
    22381 agtttgtata ttttgaaagt ccataacgtt tcctcatttc ttgtaagctt cccctcttaa
    22441 aatttaagag gggagcaaat tttcacttgt caaaggtcgt taggtaagtt atacttgagt
    22501 tacaattaat tcaagtgtaa gtaccttttt agaaatcttt tgtcgttagc aaaaggtttc
    22561 tttttttata gtaaattttt aagttttcca ttgttaattt cccactcgta ccattctgta
    22621 aaatcttgag ggaaaccatt gaccgcatat tttgcttgtt ctttggcttc ttcttcgttg
    22681 attgggtcaa gggctgtcgg tttgtctttt ggtcgtgcat aacagcctat ccatgtttca
    22741 aagtcgccct caaagcaacc gtcaataatc aatccccatt cgtttaattc tgttcttgct
    22801 tgttctttta gttcttcaat tctgtttctc atatactttc agtccttcca ttctttatga
    22861 tttagaaaat attctagttg atataaacgg tcattcgcat ttttcaaaca accataatta
    22921 agtagtaacg tcactgtgtc atttgtgata atggcttcac ttaatttctg gtgttctttt
    22981 ct
//
