LOCUS       NZ_CP074544.1          15271 bp    DNA              UNK 01-JAN-1980
DEFINITION  NZ_CP074544.1 Klebsiella pneumoniae strain S24_CRE24 plasmid
            pCRE24_3, complete sequence.
ACCESSION   NZ_CP074544
VERSION     NZ_CP074544.1
KEYWORDS    .
SOURCE      .
  ORGANISM  .
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-06-08 00:07:16
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..7049
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[363:2049]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      364..2049
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..7049
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..7049
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             364..2049
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Cloacin"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1"
                     /sec_met_domain="Cloacin (E-value: 2.1e-113, bitscore:
                     367.1, seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGGDGRGPGNSGLGHNGGQASGNVNGTSGKGGPSSGGGTDPNSG
                     PGWGTTHTPNGDIHNYNPGEFGNGGSKPGGNGGNSGNHSGSSGGGQSSATAMAFGLPAL
                     ATPGAEGLALSVSGDALSAAVADVLAALKGPFKFGLWGIAIYGVLPSEIAKDDPKMMSK
                     IVTSLPADTVTETPVSSLPLDQATVSVTKRVADIVKDERQHIAVVTGRPMSVPVVDAKP
                     TKRPGVFSVSIPGLPSLQVSVPKGVPAAKAPPKGIIAEKGDSRPAGFTAGGNSREAVIR
                     FPKESGQKPVYVSVTDVLTPAQVKQRLEEEKRRQQAWDAAHPEEGLKREYDKAKAELDA
                     EDKNIATLNSRIASTEKAIPGARAAVQEADKKVKEAEANKDDFVTYNPPHEYGSGWQDQ
                     VRYLDKDIQNQNEKLKAAQTSLNEMNESLSRDKAALSGAMESRKQKEKKAKDAENKLNE
                     EKKKPRKGTKDYGHDYFPDPKTEDIKGLGELKEGKPKTPKQGGGGKRARWYGDKKRKIY
                     EWDSQHGELEGYRASDGEHLGAFDPKTGKQVKGPDPKRNIKKYL"
     CDS             2059..2316
                     /locus_tag="ctg1_2"
                     /transl_table=11
                     /translation="MGLKLHIHWFDKKTEEFKGGEYSKDFGDDGSVIESLGMPLKDNIN
                     NGWFDVEKSWVSILQPHFKNVIDISKFDYFVSFVYRDGNW"
     CDS             3191..3319
                     /locus_tag="ctg1_3"
                     /transl_table=11
                     /translation="MEKRHLRGLAVLPHMLVPCLFTESVGNFACVRSARRSLTAGA"
     CDS             4031..5995
                     /locus_tag="ctg1_4"
                     /transl_table=11
                     /translation="MFNTDSLAWKWHIPELARQIYPWVSWLYQEYYGLAGAFLVIGLFF
                     GLAELWAGRMRFVGLSHKERREYADRYKRDNKRPAPFSVLASLDSPGRMVRARRHVWNY
                     AYWLTGAAGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLA
                     VGIVLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNA
                     LADFSSEQARQEQAVFLGKDEQGKPVLVPRDTWRKTNIQILGLPGSGKSVMATNALIRC
                     VRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLI
                     AGLNLGETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLIT
                     RLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARD
                     EFREWPHVSVMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPAEFV
                     KTTVLDNTPIRWFYRAASLESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQK
                     EARPLFDVNTLQHLPDGFAVMTGLGVARMAFSSPLRVERREIPLQRFPVLAKTDPLAEF
                     RPPADGGGPKADDDFAGIY"
     CDS             5995..6726
                     /locus_tag="ctg1_5"
                     /transl_table=11
                     /translation="MALELYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRTKYPVDGRQVSVWGLTPHGVAFSFDEDEPLADVIPFQP
                     SRVSAAHLPHRLAVQSLRLDMEARGATGWRILHRLSLKGMKVPDALAELDGKTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRKANGIDEIWYICPDRATQVRVQRAILSVDEIVNPQTGEA
                     RKTAELDRERLFACFKFMTTE"
     CDS             6733..7263
                     /locus_tag="ctg1_6"
                     /transl_table=11
                     /translation="MALYMVFIEDAEDRNGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGKNPQWERNKPTGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQINAMIDVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
     CDS             complement(7291..7470)
                     /locus_tag="ctg1_7"
                     /transl_table=11
                     /translation="MTKQEKTALNMAKFIKEQSLLLLDKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
     CDS             7539..7916
                     /locus_tag="ctg1_8"
                     /transl_table=11
                     /translation="MAWVTVRQATELTGKARSSLYRDMAKGRVSYRTEADGGRVVDTSE
                     LIRVYGELRQDETHERDELRLSGETEKMASDALIAEIKALREEVAGLRQEMQSMRLLEH
                     KPETAETPAGTPRRWWPWGKR"
     CDS             complement(7978..8277)
                     /locus_tag="ctg1_9"
                     /transl_table=11
                     /translation="MPYDVEWKQGAIEDVTTLFDYIAENSSLWDAQNVTDRVLAAADKL
                     ADFPRLYEVDSRYGEDVRRISLMGQHVLYDVDDQTRKVRVLAVVGQRQNPHIVL"
     CDS             complement(8267..8530)
                     /locus_tag="ctg1_10"
                     /transl_table=11
                     /translation="MSNTTHYENANFLRELAESLPRILPEGGPDKAALLQRLANEELAQ
                     AEYEDQVRAKVTAARADTRPGMTTEQLRQRLHGRYQELRDAV"
     CDS             complement(8836..9255)
                     /locus_tag="ctg1_11"
                     /transl_table=11
                     /translation="MRRSGSKLCLIAMITATATLTACAPKGSVEQHTRHYVYASDDGFD
                     PNFSTQKADTTRMMVPFFRQFWDMGAKDKATGKSRSDVQQRIQQFHSQEFLNSLQGTTQ
                     FAGTDYRSKDLTPKKSRLLADTISAVYLDGYEGRQ"
     CDS             complement(9332..12337)
                     /locus_tag="ctg1_12"
                     /transl_table=11
                     /translation="MPVDFLTTEQVESYGRFTGEPDELQLARYFHLDEADKEFIGKSRG
                     DHNRLGIALQIGCVRFLGTFLTDMNHIPSGVRHFTARQLGIRDITVLAEYGQRENTRRE
                     HAALIRQHYQYREFAWPWTFRLTRLLYTRSWISNERPGLLFDLATGWLMQHRIILPGAT
                     TLTRLISEVREKATLRLWNKLALIPSAEQRSQLEMLLGPTDCSRLSLLESLKKGPVTIS
                     GPAFNEAIERWKTLNDFGLHAENLSTLPAVRLKNLARYAGMTSVFNIARMSPQKRMAVL
                     VAFVLAWETLALDDALDVLDAMLAVIIRDARKIGQKKRLRSLKDLDKSALALASACSYL
                     LKEETPDESIRAEVFSYIPRQKLAEIITLVREIARPSDDNFHDEMVEQYGRVRRFLPHL
                     LNTVKFSSAPAGVTTLNACDYLSREFSSRRQFFDDAPTEIISQSWKRLVINKEKHITRR
                     GYTLCFLSKLQDSLRRRDVYVTGSNRWGDPRARLLQGADWQANRIKVYRSLGHPTDPQE
                     AIKSLGHQLDSRYRQVAARLGENEAVELDVSGPKPRLTISPLASLDEPDSLKRLSKMIS
                     DLLPPVDLTELLLEINAHTGFADEFFHASEASARVDDLPVSISAVLMAEACNIGLEPLI
                     RSNVPALTRHRLNWTKANYLRAETITSANARLVDFQATLPLAQIWGGGEVASADGMRFV
                     TPVRTINAGPNRKYFGNNRGITWYNFVSDQYSGFHGIVIPGTLRDSIFVLEGLLEQETG
                     LNPTEIMTDTAGASDLVFGLFWLLGYQFSPRLADAGASVFWRMDHDADYGVLNDIARGQ
                     SDPRKIVLQWDEMIRTAGSLKLGKVQASVLVRSLLKSERPSGLTQAIIEVGRINKTLYL
                     LNYIDDEDYRRRILTQLNRGESRHAVARAICHGQKGEIRKRYTDGQEDQLGALGLVTNA
                     VVLWNTIYMQAALDHLRAQGETLNDEDIARLSPLCHGHINMLGHYSFTLAELVTKGHLR
                     PLKEASEAENVA"
     CDS             12499..13056
                     /locus_tag="ctg1_13"
                     /transl_table=11
                     /translation="MRIFGYARVSTSQQSLDIQIRALKDAGVKANRIFTDKASGSSTDR
                     EGLDLLRMKVEEGDVILVKKLDRLGRDTADMIQLIKEFDAQGVAVRFIDDGISTDGDMG
                     QMVVTILSAVAQAERRRILERTNEGRQEAKLKGIKFGRRRTVDRNVVLTLHQKGTGATE
                     IAHQLSIARSTVYKILEDERAS"
     CDS             13239..13844
                     /locus_tag="ctg1_14"
                     /transl_table=11
                     /translation="MSIQHFQTKLGITKYSIVTNSNDSVTLRLMTEHDLAMLYEWLNRS
                     HIVEWWGGEEARPTLADVQEQYLPSVLAQESVTPYIAMLNGEPIGYAQSYVALGSGDGW
                     WEEETDPGVRGIDQLLANASQLGKGLGTKLVRALVELLFNDPEVTKIQTDPSPSNLRAI
                     RCYEKAGFERQGTVTTPDGPAVYMVQTRQAFERTRSVA"
     CDS             13926..14183
                     /locus_tag="ctg1_15"
                     /transl_table=11
                     /translation="MIAEVSTQLSEVVGVIERHLEPTLLAVHLYGSAVDGGLKPHSDID
                     LLVTVTVRLDETTRRALINDLLETALLQIVGGDKLIIPFC"
     CDS             14195..14899
                     /locus_tag="ctg1_16"
                     /transl_table=11
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
ORIGIN
        1 ttatatatcc gcaggctatc ttatcatcag tttctgaccg tgttcagtga ccgaacaacc
       61 cgaaccagac ccccgtttct tttcctgtcc cggagggggc tttctggtat ctcatataat
      121 gatttcagta aaacatactg aggccggaga acggcgccgt ttgtgctggt ttttgttgca
      181 tctggagggg attgcgcatg gtgtgagtgg ctgttttttt gatcattttc acaaaaacgc
      241 aaatttacag acttgacatg aaaaacaagg cagcgtaatt tttatactgt atataaaacc
      301 agtggttata tgtacagtat tttattttag tttattgttt taaaagtcaa agaggaaaag
      361 tatatgagtg gcggagacgg acgaggtccg ggtaattcag gtctgggaca caatggtggt
      421 caggccagtg ggaatgtgaa cggtacatca ggtaaaggtg gcccttcatc aggtggtggt
      481 acggatccaa acagcgggcc gggctggggt acgacgcata cacctaacgg ggatattcat
      541 aactataacc cgggggagtt tggtaacggc gggagtaaac ccggtggtaa tggcggtaac
      601 agcggcaatc atagcgggag ctctggtggc ggacagtctt cggccaccgc gatggccttc
      661 ggtctgcctg ccttggccac tccgggggct gaaggactgg ctttatccgt ttccggcgat
      721 gcgttgtcgg ccgctgttgc tgatgtgctg gctgccctga aaggtccgtt taagtttggt
      781 ctgtggggga ttgcgattta cggagtgctg ccttctgaga tagcaaaaga tgatccgaaa
      841 atgatgtcaa aaatcgtgac gtcattgccg gcagacacgg taacggagac gccggtcagc
      901 tccctgccgc tggaccaggc gacggtcagc gtcactaaac gtgtggcgga tattgtgaag
      961 gacgagcggc agcatattgc ggttgtcacc ggccggccaa tgagtgttcc tgtggtggat
     1021 gcgaaaccga caaaacgtcc gggggtattc agtgtgtcga ttccgggtct cccgtctctg
     1081 caggtgagcg tacctaaagg tgttccggcc gcgaaagccc cgccaaaagg cattattgct
     1141 gaaaaaggtg attcacgtcc ggctggtttt acggccggtg gtaactcccg tgaagccgtt
     1201 attcgtttcc cgaaagagag cggacagaaa ccggtctatg tgtcggtgac ggatgttctt
     1261 actccggcac aggtaaaaca gcgtctggag gaagaaaagc gtcgccagca ggcatgggac
     1321 gctgctcacc cggaagaggg gctgaaaaga gagtatgata aagcgaaagc tgagctggat
     1381 gctgaagata aaaatattgc gaccttaaac agtcgcattg catcgacaga gaaggcgatc
     1441 cccggtgcaa gggctgctgt tcaggaagcc gataaaaagg taaaagaggc agaggcaaat
     1501 aaagatgatt ttgtgactta taacccgcct catgaatatg gctccgggtg gcaggatcag
     1561 gttcgctatc ttgataagga tattcagaat cagaatgaga aattaaaagc tgcccagaca
     1621 tctttaaacg aaatgaatga atccttatcc agggataagg ctgcgctttc cggggcgatg
     1681 gagagccgga aacaaaagga gaaaaaagcg aaggatgcag aaaataaatt aaatgaggaa
     1741 aagaaaaaac ctcgtaaggg aactaaagat tacggccatg attattttcc tgatcccaag
     1801 actgaagata ttaaggggtt gggagagttg aaagagggta aacctaaaac ccctaaacaa
     1861 ggtggtggtg gtaagcgggc ccgatggtat ggtgataaaa agcgtaaaat ttatgaatgg
     1921 gattcccagc acggtgagct tgaagggtac cgcgccagtg atggcgaaca cctcggggca
     1981 ttcgatccaa aaacgggtaa gcaggttaaa gggccggatc caaaacgaaa cattaaaaaa
     2041 tatctttaag aggtaaatat ggggcttaaa ttacatattc attggtttga taagaaaacc
     2101 gaagagttta aaggtggtga atactcaaaa gacttcggtg atgatggttc tgtcattgaa
     2161 agtctgggga tgcctttaaa ggataatatt aataatggtt ggtttgatgt tgaaaaatca
     2221 tgggtttcga tattacagcc acactttaaa aatgtaatcg atattagtaa atttgattac
     2281 tttgtatcct ttgtttaccg ggatggtaac tggtaagcaa aagttatcaa ggatgatttg
     2341 aaatacagac ttccggtgtt cagggatgaa taccggggtt tttaaataca gggaaggtat
     2401 atgaaaaagg taaaggttgt ttttcttttt atattgattt tttcaggctt tcttctggtc
     2461 gcatgtcagg caaactatat ccgggatgtt cagggtggaa cggtggcacc atcgtcctcc
     2521 tctgaactga cggggatcgc ggttcagtag aaaagatcaa aggatcttct tgagatcctt
     2581 tttttctgcg cgtaatcttt tgccctgtaa acgaaaaaac cacctgggga ggtggtttga
     2641 tcgaaggtta agtcagttgg ggaactgctt aaccgtggta actggctttc gcagagcaca
     2701 gcaaccaaat ctgtccttcc agtgtagccg gactttggcg cacacttcaa gagcaaccgc
     2761 gtgtttagct aaacaaatcc tctgcgaact cccagttacc aatggctgct gccagtggcg
     2821 ttttgcgtgc ttttccgggt tggactcaag tgaacagtta ccggataagg cgcagcagtc
     2881 gggctgaacg gggggttctt gcttacagcc cagcttggag cgaacgacct acaccgagcc
     2941 gagataccag agtgtgagct atgagaaagc gccacacttc ccgcaaggga gaaaggcgga
     3001 acaggtatcc gggaaacggc agggttggaa caggagagcg caagagggag cgattcatcg
     3061 gaaacggtga tgatctttaa gtcctgtcgg gtttcgccac tcctgactga ttcatggttg
     3121 agccaccggc tcccacagat gcaccgaaaa agcgtctgtt tatgtgaact cagtcaggag
     3181 ggcggagcct atggaaaaac gccacctgcg tggccttgcc gttttgcctc acatgttagt
     3241 cccctgctta ttcacggaat ctgtgggtaa ctttgcatgt gtccgcagcg cccgccgcag
     3301 tctcacggcc ggagcgtagc gaccgagtga gcgaggaggc gcaatttccc cggcacctac
     3361 aagacggaca ccggacgcgc tgatgtggca tattgtcccc tgattaagtc tttatattcc
     3421 ctgataataa attaccagga taggtgaatc atatcggttt ttcgctgaac attttacgtt
     3481 aacctatctc tgttgctttt ttctccttac ggagaaatac aggtcatccc cgcgagggcg
     3541 tggctgacct cagggggata tcccctgctt acgctggctg gacgccaccg acgcacggtc
     3601 tctccccctc tttctggctc cgtccggctg gacgccggcc acgccagaaa ttcacccggc
     3661 ccccgtcagg ctcacgcctg accacccaca aaaatccacg gtgctggacg cacctggcga
     3721 agcagcaaag ctgctcctga ttttgcgggt ggtcagccgc tcgctatggc gaactctgac
     3781 gggggccgga acaccggaaa agaccgcact ggggtgccgc cttttcctct cacacgctgg
     3841 ggcgtgctcg ttgttcctcc ggggctgcgc cttttccgca tggggcggaa agaggctggc
     3901 ctccgtggtg aaagctgaac gcaatcacca cggacgtgac cgccgccgcc atgccttggg
     3961 gcatgtccgc ggcttgtgca gcgggggctg cacatcacgc cggcaaacca tcgtctgaag
     4021 gagagagaac atgtttaata cggattcgct tgcctggaag tggcacattc cggagctggc
     4081 ccggcagatt tatccgtggg tcagctggct gtaccaggag tattacggtc tggccggggc
     4141 tttcctagtt atcggcctgt ttttcggtct ggctgaactt tgggccggac ggatgcgttt
     4201 tgtggggctg agtcataagg agcgacggga gtatgccgat cgctataagc gcgataataa
     4261 acggccagcg ccattttcgg tgctggcctc gctggattcg cccgggcgga tggtcagggc
     4321 acgtcgacat gtctggaact acgcgtactg gctgaccggc gcggccggtc tggcccttct
     4381 gggggggctg gttgtcgccg tgtttatcga gagctgggga gaaaccgtcc tgcgtccgga
     4441 cctctacgca aacgcagatt attacctgct gcagccggct aacctgttcg ggattgcctg
     4501 gtgcgcgggc gggctggctg tcgggattgt gttggcgcgg ctgctggcgt tcctgctgct
     4561 tgacggtcat tttgcggctg ctgacgaggc ggtgaacgcg aaactgaatc aggagagccg
     4621 gcgcagcagc cagcggacag gagagatgac cgacgtgcgc cacctgcatt tcggggagcc
     4681 ggtaccggtt aatgcgctgg ccgatttttc ctcggagcag gcccggcagg agcaggcggt
     4741 gtttctgggt aaggatgagc agggcaagcc ggtgctggtt ccgcgtgata cctggcgcaa
     4801 gaccaacatt cagatcctcg gcctgcccgg gagcggcaag agcgtgatgg ccaccaacgc
     4861 gctcattcgc tgcgtacgcg atttcgggga cgcggtggtg tacttcgacc ccaaagggga
     4921 cgcatgggcg ccgcacgtct tccgggcgca ctgtccggac ttcaccctgc tggatctgcg
     4981 gccggggaaa ccggcgcagc tgaatctgtt ccgcgatctc gaccagtacg cgctgaaaaa
     5041 cctgctgatt gccgggctta acctgggcga gaccggcgac gtggcggacc actaccgcat
     5101 cagcgagcag aaagcggcga agctgattgc ggagcagttt ccgcaggggg caaacattca
     5161 gcaggtgctg gcggcggcgt acgcgctgcc ggaggccctg aaaaaggacg tgaaggggtt
     5221 gatcactagg ctggaaaacg tcgctgacct gagcgtcctg cagacggaca gtggcatcga
     5281 tgtggcgggg attatcaacg gcggcggctg cctgtacgtt atcggctcga tggacgacga
     5341 ggcggtgatc cgtgtgcaaa aaatgctgtt tgcccgctgc gcgcaaatca tcattgcgcg
     5401 ggacgagttc cgggagtggc cacacgtcag cgtgatgctc gatgaaatta aatatctgct
     5461 gtcgaagtat gtactgaacg cactggggac gctgcgcagc cgggactgca atctgttgct
     5521 cgcgcaccag tcgctgggcg atttcgggca gtgcgggcag gatctgcccg ctgaatttgt
     5581 gaaaaccacg gtactggata acacgccgat ccgctggttt taccgggcgg ccagcctgga
     5641 gtccgcgcag tgggcggcgg ggcagaccgg ggaaatcagg gtggacgtgg agcgccgccg
     5701 tgccagccgg gaggcgggga acgtggagca tatcagcggg gacagcttca tccagaagga
     5761 ggcgcggccg ctgtttgacg tgaacaccct gcaacacctg ccggacgggt tcgcggtcat
     5821 gaccgggctg ggtgtggccc ggatggcgtt cagcagtccg ctgcgggttg agcgccggga
     5881 aatcccgttg cagcgtttcc cggtgctggc gaaaaccgat cccctggcgg agttccggcc
     5941 cccggccgac ggcggcgggc cgaaagcgga tgatgatttt gcggggattt actgatggcg
     6001 ctggagctgt acaacgtcag ccacgcgaaa cgacaggcgc ggaacgcgga gaaaacccgg
     6061 ctgaccctgc gctggttgcg ggaagagctg tgttccacgg cggagctggt tgcgcggcgg
     6121 ctggggattg cggcggtgca gccggtctac cgcttcctcg acagcctggt ggcgaaaggg
     6181 ctgctggtcc ggaccaaata tccggtggac ggccgtcagg tcagcgtgtg ggggctgacg
     6241 ccgcatggcg tggcgttctc gttcgacgag gacgaaccgc tggcggatgt tattccgttt
     6301 cagccgtcaa gggtgtcggc agcacatctg ccgcaccggc tggccgtgca atccctgcgc
     6361 cttgatatgg aagccagagg ggccaccggc tggcgcattc tgcaccgtct gagtcttaaa
     6421 ggcatgaaag tgccggacgc cctggcggag ctggacggta aaacggtggc gtttgaggtg
     6481 gagcgcaccg tcaagagccg tcgccggtat caggaagtgg tgtccgggta tctgttcaac
     6541 cgcaaagcta acggcatcga tgaaatctgg tacatctgcc cggaccgggc gacgcaggtc
     6601 agggtgcagc gggcaatcct gtcggtggat gaaatcgtga acccacagac cggcgaggcc
     6661 cgcaaaacgg cagagctgga tcgtgaacgg ttgtttgcgt gctttaaatt tatgacaacg
     6721 gagtgaggga ttatggcgct gtacatggta tttattgaag acgcggagga ccggaacggc
     6781 gagcgctgca tcatgccgac cagcgagcat ctggaagata tggtggtgct cgcctggcag
     6841 accggggcgt atgttttctg ttttgtcgac cgggcccagc atctggcgat gatgaaatcc
     6901 atcgggatgt atgacgagcg gctcaacagc gacgaaaaag ccacgtactt tttcactggt
     6961 aaaaatccgc aatgggaacg gaacaaaccc acaggaatga agctgtgtga ttacctctat
     7021 cgcaaggtgg agcggttcgc catcgagaac ggtgtgcagg tggttgatgc cgggaagtgc
     7081 tcaccggagc agattaacgc gatgattgac gtggtgagtg agcggcacgg ggaaagcgcg
     7141 gtgaacgaga agctgaaagc ggagctgatg cgggaatata acagccgcta ttttaacgtg
     7201 ccggtacctg aactgccgga ggacaaacct gcccgccggt ggtggccgtt cggcaaaaaa
     7261 taaatgccag caccggccat gccggtgctg ttattcctcc ccgagcttat cccgcatcac
     7321 ctgccagagt gtttccgcat cctcgtgtag ccgctcgcac atgtcggccg gggtatccat
     7381 atccagctca ttcagtttat cgagcaatag cagcgactgc tccttaataa atttagccat
     7441 attgagggct gttttttcct gttttgtcat gattctttcc ttccgggcat ggtgtgcgcc
     7501 tgtcaggtat actgtctcaa aaatagcggg gtgagacaat ggcgtgggtg acggtgagac
     7561 aggcgacgga actgacgggt aaagcccgaa gttccctgta tcgggatatg gcgaaaggcc
     7621 gcgtatcata ccgtacggaa gctgatggcg gccgggtggt ggataccagc gagcttatcc
     7681 gggtgtacgg tgagttaaga caggatgaga ctcacgagcg ggacgagttg agactgtcgg
     7741 gtgagactga aaaaatggcc tccgacgcgt tgatcgcgga gataaaagca ctcagggagg
     7801 aggtggccgg gctacggcag gaaatgcagt ccatgagact gctggaacac aaaccggaga
     7861 cagcagagac cccggccgga acaccgcgcc ggtggtggcc gtggggaaaa cgctgacgcg
     7921 ctgtgcttgt ccaaccggcg acggccacgc aatgaattgc gtccccgtca ccggttatta
     7981 gagaacaata tggggattct ggcgctggcc gaccacggcc agaacccgga cttttctggt
     8041 ctggtcatca acatcataga ggacatgctg tcccatcaga ctgatccggc gaacgtcctc
     8101 gccatagcgt gagtccactt catagagtcg cgggaagtcg gccagtttgt ccgccgcagc
     8161 gagaacccgg tcggtaacgt tctgcgcatc ccacagggat gaattttccg cgatatagtc
     8221 aaacagcgtc gttacatcct cgatggctcc ctgcttccat tccacgtcat acggcatcgc
     8281 gcagttcctg ataacggcca tgcaggcgct ggcggagttg ttccgtggtc atacccggac
     8341 gcgtgtcagc acgggcggcg gtcactttgg cgcgaacctg atcttcatac tctgcctggg
     8401 ccagttcttc gttagccagt cgctgcaaca gcgcagcttt gtccgggcca ccttccggca
     8461 gtatgcgggg caggctttca gccagttccc gaagaaagtt ggcgttttcg tagtgtgtag
     8521 tgttgctcat tgcggagcct cccgggttaa tgcggcaata tgaaggaagt ttagcagggg
     8581 gcggtctgaa agaatatggt cgtgtcagtc aggctgatga agcagaaagt cggtaaaaaa
     8641 gggcttacgg catccatttt acgtcaaaac atatgccatg cagttgcgtg cataggcatg
     8701 cattaggata aaatttatcg ggcgcgtttc cggcagtttt ccgggggggt tgttgcctgt
     8761 tttatcccgt agccgccgga aacgccctga gcccgtctga gcggtgcgcg taatgacgcg
     8821 ttatggtaaa tccacttact gtctgccttc atagccatcg agataaacag ctgaaatggt
     8881 gtcagccagt agccttgatt ttttcggtgt gaggtctttg ctgcggtaat cggtacccgc
     8941 aaattgtgtt gtgccttgga gtgagtttaa aaattcctga ctgtgaaact gctgaatgcg
     9001 ttgctgcaca tcactccgtg attttccggt cgctttatcc tttgcgccca tatcccagaa
     9061 ctgccggaaa aaaggcacca tcattcgtgt tgtgtcagct ttctgggtgg aaaaattggg
     9121 atcaaaaccg tcatctgaag catatacgta atgccgggta tgctgttcca cgctgccctt
     9181 tggagcacag gcagtgagag ttgctgtcgc tgttatcatg gcgataagac acagtttgct
     9241 gccggaacgt ctcatgagcg tctccttacc tttaattctt ttttctcatt gagttatagg
     9301 ggtctgacgc tcagtggaac gaaaactcac gttaagcaac gttttctgcc tctgacgcct
     9361 cttttaatgg tctcagatga cctttggtca ccagttctgc cagcgtgaag gaataatggc
     9421 cgagcatatt gatatgtccg tggcaaagcg gggagaggcg tgcgatatct tcatcattca
     9481 gtgtttcacc ctgcgcccgg agatgatcca gagctgcctg catataaata gtgttccata
     9541 acacgacggc gttagtgacc agccccagag ctcccaactg atcttcctga ccgtcggtat
     9601 atcgttttct tatctcacct ttttgaccgt gacagatggc tctggcaact gcatgacggc
     9661 tttctccccg attaagctgg gtcagaatgc gccggcggta atcttcatca tcaatataat
     9721 taagcagata cagcgttttg ttgatgcgcc ccacttcaat gattgcctga gtcagtccgg
     9781 agggacgttc acttttcagc aatgaacgga ccagcactga ggcctgtact ttgcccagct
     9841 tcagggagcc tgcggtccgg atcatttcgt cccactgaag gactattttt cggggatctg
     9901 attgccctct ggcaatatca ttcagcacgc catagtcggc atcatggtcc attcgccaga
     9961 aaaccgaagc accggcatca gccaggcgtg gagaaaactg gtatcccagc agccagaaaa
    10021 ggccaaagac aagatcgctg gcacctgccg tatcggtcat aatttcggtt ggattcagcc
    10081 cggtctcctg ttccagaagg ccttccagca caaagataga gtccctcagc gtccccggta
    10141 taacgatgcc atgaaagccg gaatactgat cggacacaaa gttgtaccag gtgatccctc
    10201 tgttattacc aaagtatttg cggttcggtc cggcattgat tgttctgact ggcgtaacaa
    10261 agcgcattcc atctgcagat gccacttctc ctccacccca tatctgtgcc agtggcagcg
    10321 ttgcctgaaa atcaaccagt ctggcattag cgctggtgat agtttcagcc cgcagatagt
    10381 tcgcttttgt ccagttcagc cggtgtcggg tcagtgcagg aacatttgat ctgatcagtg
    10441 gttccagacc gatattgcag gcttcagcca tcagcacggc gctgatgctg acgggcagat
    10501 catcaactct ggcactggct tcactggcat ggaaaaactc atcagcaaat ccggtatggg
    10561 cgttaatttc gagcagcaac tccgttaaat ccaccggagg gagcagatca ctgatcattt
    10621 tgctcagtcg tttcagactg tccggctcat caagactggc gaggggagaa attgtcaacc
    10681 ggggcttcgg gccagaaaca tcgagttcga cagcctcatt ttcgccaaga cgtgcagcaa
    10741 cctgtctgta acgactatca agctgatggc ccagagattt tattgcttcc tgcgggtctg
    10801 tcgggtgccc caaagaacga taaaccttaa tccgatttgc ctgccagtca gcaccctgta
    10861 gtaatcttgc acgaggatct ccccaccggt tactgccggt aacgtagaca tccctccgtc
    10921 tcagactatc ctgcagttta ctgagaaagc agagcgtgta tccccttcgg gtgatatgtt
    10981 tttccttgtt aatcaccagc cgtttccatg actgactgat gatttccgtt ggtgcgtcgt
    11041 caaaaaactg ccgccgtgag ctgaactccc ggctgaggta gtcacaggca ttcagagtgg
    11101 taaccccggc aggtgcggat gaaaatttaa cggtattcag cagatggggc aggaaacgac
    11161 gaacgcgccc gtactgctcc accatttcgt catgaaaatt atcgtctgag ggccgggcaa
    11221 tttcacggac aagcgtgatg atttcagcca gcttttgcct agggatgtag ctgaacacct
    11281 cagcacgaat cgattcgtcc ggtgtttctt ctttcagcaa gtacgaacat gcgctggcga
    11341 gcgccaatgc agatttatcc agatccttca gcgagcggag ccgttttttc tgcccaatct
    11401 ttctggcgtc acggatgata acggccagca tggcgtccag aacgtccagt gcatcatcca
    11461 gcgccagcgt ttcccatgca aggacaaagg caaccagaac cgccatcctt ttctgcggtg
    11521 acatcctggc aatattgaac accgaagtca taccagcata acgtgcgaga tttttcaggc
    11581 gcacagccgg gagtgtactc aggttttcag catgcaggcc aaaatcgttc agagttttcc
    11641 agcgttcaat tgcttcatta aacgccggac cactgatggt cacagggcct tttttcagtg
    11701 attccagtaa agacaggcgg ctgcaatcag ttggccccag cagcatctcc agctgtgaac
    11761 gctgttcggc tgacggtatc agtgccagtt tgttccacag gcgcaacgtc gccttttccc
    11821 ttacctctga aatcaaccgg gtcagcgtgg tggctccggg gagaataata cgatgttgca
    11881 taagccaccc tgtcgccagg tcgaaaagca ggccaggacg ttcgttgctt atccagctcc
    11941 gggtatataa aagacgggta aggcgaaatg tccagggcca ggcaaattca cgatactgat
    12001 agtgctgacg tatcagcgct gcatgctcac ggcgggtatt ttccctctga ccgtattctg
    12061 caagaacggt gatatcacga atcccgagct gtctggcggt aaaatgccgg acgccggaag
    12121 gaatatgatt catgtcagta agaaaagtgc ccagaaaacg cacacacccg atttgcaggg
    12181 caataccaag tcgattgtga tcaccccggc ttttcccgat aaattcttta tccgcttcat
    12241 caagatgaaa ataacgcgcc agctgaagtt catcgggttc gccagtgaac ctgccataac
    12301 tctcaacctg ctcagtggtc aaaaaatcaa cgggcatatc ggcctccctg cctgacggct
    12361 tttttaacac aactgcaacc gttcgaaata ttataaatta tcagacatag taaaacggct
    12421 tcgtttgagt gtccattaaa tcgtcatttt ggcataatag acacatcgtg tctgatattc
    12481 gatttaaggt acatttttat gcgaattttt ggttatgcgc gggtctcaac cagccagcag
    12541 tccctcgata ttcagatcag agcgctcaaa gatgcagggg taaaagctaa ccgcatcttt
    12601 accgacaagg catccggcag ttcaacagat cgggaagggc tggatttgct gaggatgaag
    12661 gtggaggaag gtgatgtcat tctggtgaag aagctcgacc gtcttggccg cgacaccgcc
    12721 gacatgatcc aactgataaa agagtttgat gctcagggtg tagcggttcg gtttattgac
    12781 gacgggatca gtaccgacgg tgatatgggg caaatggtgg tcaccatcct gtcggctgtg
    12841 gcacaggctg aacgccggag gatcctagag cgcacgaatg agggccgaca ggaagcaaag
    12901 ctgaaaggaa tcaaatttgg ccgcaggcgt accgtggaca ggaacgtcgt gctgacgctt
    12961 catcagaagg gcactggtgc aacggaaatt gctcatcagc tcagtattgc ccgctccacg
    13021 gtttataaaa ttcttgaaga cgaaagggcc tcgtgatacg cctattttta taggttaatg
    13081 tcatgataat aatggtttct tagacgtcag gtggcacttt tcggggaaaa gtgcgcggaa
    13141 cccctatttg tttatttttc taaatacatt caaatatgta tccgctcatg agacaataac
    13201 cctgataaat gcttcaataa tattgaaaaa ggaagagtat gagtattcaa catttccaaa
    13261 caaagttagg catcacaaag tacagcatcg tgaccaacag caacgattcc gtcacactgc
    13321 gcctcatgac tgagcatgac cttgcgatgc tctatgagtg gctaaatcga tctcatatcg
    13381 tcgagtggtg gggcggagaa gaagcacgcc cgacacttgc tgacgtacag gaacagtact
    13441 tgccaagcgt tttagcgcaa gagtccgtca ctccatacat tgcaatgctg aatggagagc
    13501 cgattgggta tgcccagtcg tacgttgctc ttggaagcgg ggacggatgg tgggaagaag
    13561 aaaccgatcc aggagtacgc ggaatagacc agttactggc gaatgcatca caactgggca
    13621 aaggcttggg aaccaagctg gttcgagctc tggttgagtt gctgttcaat gatcccgagg
    13681 tcaccaagat ccaaacggac ccgtcgccga gcaacttgcg agcgatccga tgctacgaga
    13741 aagcggggtt tgagaggcaa ggtaccgtaa ccaccccaga tggtccagcc gtgtacatgg
    13801 ttcaaacacg ccaggcattc gagcgaacac gcagtgttgc ctaacccttc catcgagggg
    13861 gacgtccaag ggctggcgcc cttggccgcc cctcatgtca aacgttaaac atcatgaggg
    13921 aagcggtgat cgccgaagta tcgactcaac tatcagaggt agttggcgtc atcgagcgcc
    13981 atctcgaacc gacgttgctg gccgtacatt tgtacggctc cgcagtggat ggcggcctga
    14041 agccacacag tgatattgat ttgctggtta cggtgaccgt aaggcttgat gaaacaacgc
    14101 ggcgagcttt gatcaacgac cttttggaaa cggcactgtt gcaaatagtc ggtggtgata
    14161 aacttatcat ccccttttgc tgatggagct gcacatgaac ccattcaaag gccggcattt
    14221 tcagcgtgac atcattctgt gggccgtacg ctggtactgc aaatacggca tcagttaccg
    14281 tgagctgcag gagatgctgg ctgaacgcgg agtgaatgtc gatcactcca cgatttaccg
    14341 ctgggttcag cgttatgcgc ctgaaatgga aaaacggctg cgctggtact ggcgtaaccc
    14401 ttccgatctt tgcccgtggc acatggatga aacctacgtg aaggtcaatg gccgctgggc
    14461 gtatctgtac cgggccgtcg acagccgggg ccgcactgtc gatttttatc tctcctcccg
    14521 tcgtaacagc aaagctgcat accggtttct gggtaaaatc ctcaacaacg tgaagaagtg
    14581 gcagatcccg cgattcatca acacggataa agcgcccgcc tatggtcgcg cgcttgctct
    14641 gctcaaacgc gaaggccggt gcccgtctga cgttgaacac cgacagatta agtaccggaa
    14701 caacgtgatt gaatgcgatc atggcaaact gaaacggata atcggcgcca cgctgggatt
    14761 taaatccatg aagacggctt acgccaccat caaaggtatt gaggtgatgc gtgcactacg
    14821 caaaggccag gcctcagcat tttattatgg tgatcccctg ggcgaaatgc gcctggtaag
    14881 cagagttttt gaaatgtaag gcctttgaat aagacaaaag gctgcctcat cgctaacttt
    14941 gcaacagtgc cctgataaat ctggagccgg tgagcgtggg tctcgcggta tcattgcagc
    15001 actggggcca gatggtaagc cctcccgtat cgtagttatc tacacgacgg ggagtcaggc
    15061 aactatggat gaacgaaata gacagatcgc tgagataggt gcctcactga ttaagcattg
    15121 gtaactgtca gaccaagttt actcatatat actttagatt gatttaaaac ttcattttta
    15181 atttaaaagg atctaggtga agatcctttt tgataatctc atgaccaaaa tcccttaacg
    15241 tgagttttcg ttccactgag cgtcagaccc c
//
