LOCUS       NZ_CP065780.1           5708 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP065780.1 Enterococcus faecium strain 16-021 plasmid p16-021_3,
            complete sequence.
ACCESSION   NZ_CP065780
VERSION     NZ_CP065780.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-06-07 22:43:53
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 3610
            Orig. end    :: 9318
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..5708
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[5000:5375]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5375
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..5708
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..5708
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             1063..1752
                     /locus_tag="ctg1_7"
                     /transl_table=11
                     /translation="MAFYLPYLLIFVSISGSIWLIYKIFQTRYSLKGSKIRFKRFFFLG
                     FIFYLIIVSSGLFGVLEGNKRVSRSILLGNVTQKYESARDKKKKEQALAQKMEEFTTCY
                     EEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYVKDTKIEEA
                     CSDLFGDTNPWFASEEEKKEKQQSVTYERYEILLQQATNMQNPTKKETALNYLKSVKEW
                     LDQQQQN"
     CDS             2603..3340
                     /locus_tag="ctg1_8"
                     /transl_table=11
                     /translation="MSNDIVRYNNGLNSVPLRKFTPIDMDLFWGICSKMKRKGTKEEIF
                     TFKQIKELIDYNINARGDRFANDLIKMSKKIITLSFIYEDEKTYEQLNLFQKFKIDKVN
                     ETLLIKVSEEFEYILNSIGTNFTRFELENMTNLKSSYVKELYRQLMAHKDRRSKKGHWF
                     VKIEDFRALLAIPESYRMRDIDKQIFAQAKKEFLNVNSTHPAIFKTFEIKKIKAYKGNK
                     IGSLQIYFEENIPSITLDNWLEK"
     CDS             3368..3907
                     /locus_tag="ctg1_9"
                     /transl_table=11
                     /translation="MQPKETFTIKELSELFEISRQAISKHVDKLDPSLLAKNERGYKVV
                     LRSGVLQLASNLGNQRLLYRLHEYEQENDKNVYISSKNVIVNELLDKLREENEFLREQL
                     SLKEQNNSNMQKLLDQQQQLTLQANQQIEKLQEQLQLAYTEETPEDESTTILSEETESI
                     EKHTKKKKQKWWQLWK"
     CDS             3923..4093
                     /locus_tag="ctg1_10"
                     /transl_table=11
                     /translation="MTRKNLLFGSILLGILGFSPMLLSVINKGNKHGELKLNPNYYNSP
                     NEELFVKETDK"
     CDS             complement(4407..4868)
                     /gene_functions="other (smcogs) SMCOG1148:hypothetical
                     protein (Score: 60.7; E-value: 3.7e-18)"
                     /gene_kind="other"
                     /locus_tag="ctg1_11"
                     /transl_table=11
                     /translation="MEDLGSKLRELRVKKGYTQEYVARKFNVTRQTISKWENNKTTPDI
                     ETLKKICEFYSTNINSILNEDNLKNKQNNLLVLTAIIFNIFVTILGLFELIQMNFFSFT
                     HGIFTWFALSGLIVIDILNYFYIYYSYLKNEKFFYTIFFPLVILIILLS"
     CDS             5001..5375
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Lactococcin_972"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_12"
                     /sec_met_domain="Lactococcin_972 (E-value: 1.7e-09,
                     bitscore: 28.1, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKFLCLSALMGVLLTSGGIVSATEALNLDVPEDHTAIYGGGMEA
                     TEEGFSSSKLRYAAGGGDFNCGVNGFKVYANYYHARAKHSATAKNGRGGQVRSVQKAGV
                     RAYATCNATLTGNTGWWNVY"
     CDS             5429..5707
                     /locus_tag="ctg1_13"
                     /transl_table=11
                     /translation="MLKKINAVLSLFVCITILFFSTNVINGIKTSEALYKNTAEIHMQY
                     KDDMDFNSYINALYEISTQENINISQYSFTAVNQLTILATNPNANKHW"
ORIGIN
        1 tgacgtcgat tatgccaaaa gtgaaatgaa acaaattcgc atgctgtatg gaaaagacga
       61 ccgtgtacag gcacacttat tgattcaatc ttttcgacca ggagaaatta ccgctgaaaa
      121 agctaatcaa ctaggggcag agtatgcaaa aaaaatagcc cccgatcacc aaatagctat
      181 ttacacacat acagacaaag accatattca taatcacatt gtcattaact ccgttaatct
      241 ggagactgga aaaaaatttc aagctcatgg tcaagcattt ctaaacaaat gttatgacct
      301 aaatgacgag atttgtcttg cacataactt accaatcact gagcgaggaa agaagccaga
      361 aaaacgaacc atgtctgaaa taaaattaaa agaaaaaaat gaacctgttt ggaaagacga
      421 aattcggatt gcgatcgatc aaacaatgaa aaacaaaaaa accagaacct atgaccaatt
      481 ttgtaattcc ctcaaaacat tggggattca ttgcttcaat cgcgggaaaa atttcactta
      541 cgaattgatc cacaaaaaga aaaaagtacg atccaacaga ctaggaaagg actacgaaaa
      601 ggagacgatt ttacatgagc tggacagacg agaacgaacc tataaccaac agcgaaccaa
      661 cgagctacga agagctcgag ctagcattcg cgaaactgca gaagaagtac gaagagaaca
      721 acgaactctt acgcctgaac aaccggaaat tagaccggct cgaagaaacc atgaacaaca
      781 cgttgaaaga ggaacagacc accaacaaga attatcgctc taaaacgtta aaagacatag
      841 aaaacgaaat aaagaaacaa cgtgcttttc tcgttcctta tacgcaagaa aggatacaaa
      901 ctacgattga tttacaagtt aaaaaactcc atcaagagct attagaccag cgaaataagg
      961 aacagaaaaa ggtgcttact caacgatcat tggattttct tgccccctta tgttgcttag
     1021 tcctgacact gttcgcattt tggttagtat ggggaggcta aaatggcatt ttatttaccc
     1081 tatctactca tttttgttag tatttcagga agtatttggc tcatctataa aatttttcaa
     1141 acaagatatt cattaaaagg ctctaaaatt cgatttaagc gatttttctt tcttggcttt
     1201 atattttact tgataatcgt ttcaagcggc ttattcggcg ttttagaggg aaataagcgc
     1261 gtttctagaa gtattttatt aggaaatgtc actcaaaagt atgaatcagc gcgtgataaa
     1321 aagaaaaaag agcaagcatt agcacaaaaa atggaagagt ttaccacttg ttatgaggaa
     1381 atgaacgata tttttgtgaa tcaagaaaaa cgtttgacgg ataaaaacat ggaaaaactc
     1441 actcgtcttt atcaaaactt gccagaaaaa cagcaaaaag aggttcaaga caactatgag
     1501 cgaaccaaaa aagacgtgca atatgtaaaa gatacaaaga tagaagaagc ctgtagtgat
     1561 ctatttggag acacaaaccc ttggtttgcc agtgaagaag aaaaaaaaga aaaacaacaa
     1621 tctgtcacat atgaacgcta tgaaatcttg cttcaacaag caactaacat gcaaaatccg
     1681 acaaaaaaag aaaccgcctt aaactatcta aaaagtgtca aggaatggtt agatcagcaa
     1741 caacaaaatt gaatttgatt taaaatcatg ttaaaatgaa tgtgcaaatg atcaaacatt
     1801 agatacacga aagccccaga gaggtcggat tctctggggc tttttttcag gttgatgtcg
     1861 cctttattga ttttacttct tgtttcggtt attcaaccaa taactgaata aagagacaca
     1921 aactcctaca agaagggggc aaatgaacag ttcaaacatt agatacacct ccttccagtc
     1981 gcaagactgt cggataggcg acaagttatt atatcttaaa aaattaaatt tgtgtggtgt
     2041 ttttaagtat cacttgtttt agggttgtta gggcttgccc tgaccgcctg taaggcgctt
     2101 ctcgactaga ttaagggaat taatcaagaa ttatcttaga acggcttaga caagctttca
     2161 gagcctcaca cctcctcttt gaacaacggt tttagcaaag gagccggagg cgactgcgca
     2221 gtataatatg agagcatagc gatcacacct ttttagcgac cgtagggagc aagttttcca
     2281 gtttagaaaa attcgcgaac ctttttggag gaaaaagtag gagtttttta ggcgggaaat
     2341 tcaatgtgct tttaagatat actgttagat atactgttag atatactgtt aataataact
     2401 gttagggatt agcaacctta tgggagagta agtattgaca taggtagtgg gggataaatt
     2461 gtcacactat gggggataaa ttgtcacact atgggggata aattgtcaca ctatggggga
     2521 taaattgtca cactatgggg gataaattgt attttacatc ctcttatgtc tatgataaca
     2581 taatttattg aggtgatttt tattgagtaa cgatatagtt cgatataata atggattaaa
     2641 ttctgtccct ttaagaaaat ttacccctat agatatggat ttattttggg gaatatgttc
     2701 taaaatgaaa agaaaaggta caaaagaaga aatttttaca tttaaacaaa taaaagaatt
     2761 aattgattac aatataaatg cacgtggcga ccgttttgct aatgatttaa taaaaatgtc
     2821 aaaaaaaatc attactttgt cttttattta tgaagacgaa aaaacatatg aacaattaaa
     2881 tctgtttcaa aaatttaaaa tcgataaagt gaatgaaaca ttattaataa aggtttctga
     2941 agaatttgaa tatatactta attcaatcgg aactaatttt actcgtttcg aattagaaaa
     3001 tatgacaaac ttaaagagta gctacgttaa agagttatat cgccaactta tggctcataa
     3061 agacagaaga tctaaaaaag gtcactggtt tgtaaaaata gaagatttta gagctctatt
     3121 agcaatacca gaaagttatc gcatgagaga tattgataaa caaatttttg cccaagcgaa
     3181 aaaagaattt ttaaacgtta attcaactca ccctgctatt tttaaaactt ttgaaatcaa
     3241 aaaaattaaa gcctacaaag gaaataagat aggatctctg caaatttatt ttgaagaaaa
     3301 tataccttca attaccttag ataattggtt agagaaataa tacctaacaa tttaggaggc
     3361 aattatcatg caacccaaag aaacctttac aataaaggaa ttatctgaat tatttgaaat
     3421 aagtaggcaa gcaatctcta aacatgttga taaattagac ccgtccttat tagctaaaaa
     3481 tgagcgtggt tataaggttg tattacgttc tggagtattg caacttgcta gcaacttagg
     3541 taaccaaagg ttactatata ggttgcatga gtatgaacaa gaaaacgata aaaacgttta
     3601 tatatcaagc aaaaacgtga ttgtaaacga gttgctagat aagttgcgtg aagaaaatga
     3661 atttttacga gaacaacttt ccctcaaaga gcaaaataat tctaatatgc aaaaattact
     3721 cgaccagcaa caacagctca ccctacaggc aaatcaacag atcgaaaaac tgcaagaaca
     3781 gttacaatta gcttatacgg aagaaactcc agaagatgaa tcaactacta ttctttctga
     3841 agaaacagaa tcgatagaaa aacacacaaa aaagaagaag caaaaatggt ggcaactttg
     3901 gaaataactg gagggaacat tcatgacaag aaaaaatctt ctattcggtt ctattttact
     3961 aggaattcta ggattcagtc cgatgttatt gtcagtaatc aataaaggga ataaacatgg
     4021 tgaattgaaa ttgaatccaa attattacaa cagtcctaac gaagaattgt ttgtaaaaga
     4081 gacggataaa taataaaaaa gactgctctt ccgagcagcc agttaaaaaa ataatgagag
     4141 tttattcttg aaaaagcaac gcgcttataa agcgctacca aaattttatc atattttata
     4201 aaaaataaca atccagtaaa aaatgactgg taaaaattca caaagaaacg gaaagaagca
     4261 actacagaaa atcaagcctt aaaaagagct ttttacctag accaattaaa aatcacaaag
     4321 tgagcgtctc tatccattgg tagaggggca acttggtcta gtgtacatta tgtcaactat
     4381 gcaattaaat aactaactac ttcatattag cttaataaaa taatcaaaat cactagggga
     4441 aaaaatattg tataaaaaaa tttttcattt tttaaataag aatagtaaat ataaaaataa
     4501 tttaagatat ctattactat taatccagat agagcaaacc aagtaaatat tccgtgtgta
     4561 aagctaaaaa aattcatttg aatcaattca aataaaccta atatagtaac aaatatatta
     4621 aaaataatag ctgtcaatac cagtaaatta ttttgtttat tttttaaatt atcttcattt
     4681 aaaatagaat ttatgttagt actataaaat tcacaaattt tttttagtgt ctctatatct
     4741 ggtgttgttt tgttattttc ccactttgaa atagtttgac gtgtaacatt aaattttctt
     4801 gccacatatt cttgagtata cccttttttc actcttaatt ctcttagctt agatcctaaa
     4861 tcctccattt tttctcctat gtaaacgatt atttacataa aattttatca taaaaatact
     4921 aacgcgccaa aaaagttctt tattttataa aacacactaa aataaaataa ttctagtaaa
     4981 aaagatagga gaaataagtt atgaaaaaat ttttatgtct ttctgcttta atgggtgtct
     5041 tattaactag tggaggaata gttagtgcta cagaagcttt aaatctagat gtacccgaag
     5101 accataccgc catttacgga ggaggaatgg aagctacaga agaaggattt tcttctagta
     5161 aattgagata tgctgctggc ggcggagatt tcaactgtgg ggttaatgga tttaaagttt
     5221 atgcaaatta ctaccatgct agagctaaac atagtgcaac agctaaaaat ggacgaggcg
     5281 gtcaagtacg atcagttcag aaagctggag taagagctta tgcaacatgc aatgccacac
     5341 ttactggaaa tactggttgg tggaatgttt attaaaaaag agagtttaaa ctctcttttt
     5401 tatttacatt tgaaaggaaa ttcaaaatat gttaaaaaaa ataaacgctg ttttatcact
     5461 ttttgtctgc attacaatac tattcttttc tactaatgtt ataaatggta taaagacttc
     5521 tgaagcgcta tataaaaata ccgctgaaat tcatatgcaa tataaagatg atatggactt
     5581 taacagttat ataaacgctt tgtatgaaat atctacacaa gaaaatatta atatttctca
     5641 atatagtttt actgctgtta accaactaac tattcttgct acaaacccta acgctaacaa
     5701 acactgga
//
