LOCUS       NZ_CP065660.1          14880 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP065660.1 Staphylococcus epidermidis strain FDAARGOS_913 plasmid
            unnamed6.
ACCESSION   NZ_CP065660
VERSION     NZ_CP065660.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-06-07 21:47:56
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14880
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14880
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2327:4880]"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2328..4880
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     cand_cluster    1..14880
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14880
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-iii"
                     /region_number="1"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     CDS             3..98
                     /locus_tag="ctg1_1"
                     /transl_table=11
                     /translation="MLMQSIKAELEEIHTLNMRRQNMPKYNIFNE"
     CDS             complement(216..470)
                     /locus_tag="ctg1_2"
                     /transl_table=11
                     /translation="MIRKLNKKDQEILKTLGSIWLNSNIATHNFINEEYWVNNYDNVIE
                     SFKTAEIIVYEKNTEIIGFCGLIDNYIAGMFIKKSSRNQ"
     CDS             complement(460..690)
                     /locus_tag="ctg1_3"
                     /transl_table=11
                     /translation="MNYFRYKQFNKDVIIVAVGYYLRYAFIKRLIKQFGKPQKIITDQA
                     PSTKVAMAKVIKTRRNSFSTRFKIKVIKNDT"
     CDS             1545..1841
                     /locus_tag="ctg1_4"
                     /transl_table=11
                     /translation="MEKKLLIITAAHSVFDWHYKKFAESISFFDYEGNEVNINRIVLSN
                     NWVSEGILDFDTAILIPDKTNDCNYNKIYPKFFYDKEQKITVLYLKDKLFKKN"
     CDS             1841..2113
                     /locus_tag="ctg1_5"
                     /transl_table=11
                     /translation="MCHEANTFEDYIYESSMIGVNLKAKEGYSGSPWYYKDEKGTYQIT
                     NTSLSFKKYKKLTFAPYWGMHMKDMFLFSENVNNVNEKYINHILY"
     CDS             2125..2268
                     /locus_tag="ctg1_6"
                     /transl_table=11
                     /translation="MNKNSVLKLQGIRTKKSTNSQASNASVMCKKQSSVSVVFCVFPQG
                     NK"
     CDS             2328..4880
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1030:serine/threonine protein kinase (Score: 69.9;
                     E-value: 4.2e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_7"
                     /sec_met_domain="micKC (E-value: 2.9e-133, bitscore: 437.4,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 3.4e-16, bitscore: 51.2,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 2.7e-43, bitscore:
                     139.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYRYVKYINNSRYYTKPSYENEGIINLKQVPHNFEIVQGEHWTN
                     VFNNTQHLPKQGWKIHICTQLKEARKTLDIVSNLMFKENVSFKYVKSMHELMLKDSKYG
                     DRSSSGKFITIYPSSNEQFIDLLKKLEHELSNLPKGPYILNDKRWYKSNVYFRYGGFMP
                     RTFRYNGEILDAIEDPNGNLIEDQRKPYYVLPDFIEEPEEIKKMNLEVDHEYKRTPLDN
                     YNIKEALHFSNGGGVYLAEHNKWGNVVLKEGRPHTSTGFDNIDAFERVENEGKVLKKLM
                     KANYPAKIYDSFSAWEHKFIVEEYIEGDSLSIWMVNKYPFSSESNNENYVKSSINILNQ
                     LIKAIKELHNLNIGFGDLQPANIIVSKEEKIRLIDFETAGSINDSLSSVMTPGFIGSPK
                     MNKGQGDWFAVLRIAKQMFIPIGSVQDISHNLDSVHNSWIKSTFGQEALHIIKKIENIC
                     KYQNSRPMKEFITSQNKTVRNFNLLSVKEKLINCIKNDLRDEELLMHGDIRQYEMNSGK
                     WNVLTGGFGVIMAVKRSGEWDEKFDKWIKSIDYSNLGYLENGLYTGKIGIANVLIESGY
                     IKEAATIIKTINIEDSNQDISLASGLSGLGFLSIYYELKENIYLDESKKIGEMLENNFQ
                     DNTPVYTFDYDIVDKGFLTGWSGASLFMSCLYRATNNEKWLHLSRKMLNKELEKTLFDD
                     TGLFQVDDDFRILPYLSSGGAGLAIPMIAYESIVNESIWRKELEGISKIAKSKTFFNGG
                     LFQGTTGIVAISNLLDNYLNKEDLTKSSLFTLNLHLIETENCIYLPGDSCFRVSSDLMS
                     GTAGLLTVVDDIINNSYFSWLPLLNIDKLINLDKITRR"
     CDS             4890..5015
                     /locus_tag="ctg1_8"
                     /transl_table=11
                     /translation="MKNVLDLQQMRSKAGKKKPTRKQSSTSWGCAPSSNTSWFFC"
     CDS             5054..5173
                     /locus_tag="ctg1_9"
                     /transl_table=11
                     /translation="MNKVLSLQQETVSKEVQLKAKSSKSQNCKNSSHSSWFIC"
     CDS             5231..6958
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 261.8; E-value:
                     2.2e-79)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_10"
                     /transl_table=11
                     /translation="MELFNLNVYNILKIAIDNKSKKIYLAVIIIISLIFTLASLYFPLI
                     IKNIITELEKNKVSVFIICYLILFLILRSVMESINEYLIAKLGNIVIKDLQQNIYDRIV
                     NYPISFFDEYNSGDLSSRLVNDTEVIKDLITFHIPKVINGLVMIVGAVCLIVLLDWKLT
                     VLILLISPVIFGIIFPLMKKLENTGEIQQNEISNFISKTQETFKNIRMVKASTAEQSES
                     KSISRYINNLFKVNLYESKVMSLVSPLVNLLLIFGLLIIAGYGAYRIQNDTLTLSTLIA
                     FIIYSFQLMSPISSISSFIGEYHKSNGAFKSLTVILSKDIENAKNTYKYNFKLEDKLIF
                     DNVSLEFKEKKILDNISFKLNKGESLTIIGPSGSGKTTLLNVIEKFYYINSGSITIDGI
                     DINDINTQNLRYNIGLVSQDIPIISGTIKDNLLYGLNNVSITNFEIKDILKSTMLKDLV
                     INQIDGINSYVGESGNRLSGGEKQRINIGRVLLKNPNIILLDEATSNLDNESKSEIINS
                     ISEITQDKTVLKITHNMHELKEDEQILFIENGKIIFKGKHGELLKNNERYKKFIKNEA"
     CDS             7038..7361
                     /locus_tag="ctg1_11"
                     /transl_table=11
                     /translation="MNIQFKKGALELLVLLIVKQEDQYGYSLSQIITNRIAISEGTIYP
                     LLRKLVREEYLESYYTPSKEGPSRKYYSITSKGNVRLNLLLREWNNFTEAINMFVKESG
                     LHE"
     CDS             7354..7923
                     /locus_tag="ctg1_12"
                     /transl_table=11
                     /translation="MNKEEYLRIIKKGIKKVDAKEKEDILNEYESHFISGYKDNKDDTE
                     IIKELGNPIKVAKEINAVNSIYKIEKEKSVKSIFSAAFSIMGLSIFNLFLIIISFFIFL
                     LLLPFVLAYFIAVPIMIFSPIILLVMGCINGFDTINTGDIFEVIKGVVLGIILAFIGYF
                     IAKYFLKLLVLYLNWNIDVYKKEKLK"
     CDS             7920..8453
                     /locus_tag="ctg1_13"
                     /transl_table=11
                     /translation="MKYIYIYLLLIFSIILVSCSNSIDNNNSKENSEDKIVEKPLPKKI
                     FDKNKDGQYITENEIRKSIKLYLDKNEELSEASEYYEDKIDSEESLSQNEIKKLKKLNN
                     LNQKNDENFKSYIKSNKLPKSYRKDTERISKYISHSNKYSQNLEKKIDKIIDKGINQKK
                     YQLKILEKSKMIVQ"
     CDS             complement(9094..9573)
                     /locus_tag="ctg1_14"
                     /transl_table=11
                     /translation="MIIGYARVSSIDQNLERQLENLKTFGAEKIFTEKQYGKSIENRPV
                     LQEALNFVRMGDRFIVESIDRLGRNYDEVINTVNYLKDKEVQLMITSLPMMNEVIGNPL
                     LDKFMKDLIIQILAMVSEQERNESKRRQAQGIQVAKEKGVYKGHLLLYSPNAKNP"
     CDS             complement(9913..10758)
                     /gene_functions="resistance (resist) PC1 (Score: 603.1;
                     E-value: 3.9e-184)"
                     /gene_kind="resistance"
                     /locus_tag="ctg1_15"
                     /transl_table=11
                     /translation="MKKLIFLIVIALVLSACNSNSSHTQELNDLEKKYNAHIGVYALDT
                     KSGKEVKFNSDKRFAYASTSKAINSAILLEQVPYNKLNKKIHINKDDIVAYSPILEKYV
                     GKDITLKELIEASMTYSDNTANNKIIKEIGGIKKVKQHLKELGDKVTNPVRYEIELNYY
                     SPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKNFLLDLMFNNKNGDTLIKDGVPKDYKV
                     ADKSGQAITYASRNDVAFVYPKGQSEPIVLVIFTNKDNKSDKPNDKLISETAKSVMKEF
                     "
     CDS             10961..12622
                     /locus_tag="ctg1_16"
                     /transl_table=11
                     /translation="MLNYKVWYLTLLAGLIPFIPIKFSFFKFNNVNNQAPTVESKSHDL
                     NHNINTTKPIQEFTTDIHKFNWDSIDNICTVIWIVLVIILSFKFLKALLYLKYLKKQSL
                     YLNENEKNKIDTILFNHQYKKNIVIRKAETIQSPITFWYGKYIILIPSSYFKSVIDKRL
                     KYIILHEYAHAKNRDTLHLIIFNIFSIIMSYNPLVHIVKRKIIHDNEVEADRFVLNNIN
                     KNEFKTYAESIMDSVLNVPFFNKNILSHSFNGKESLLKRRLINIKEANLKKQSKLILIF
                     ICIFTFLLMVIQSQFLMGQSITDYNYKKPLHNGYQILDKSKIFGSNSGSFVMYSMKKDK
                     YYIYNEKESRKRYSPNSTYKIYLAMFGLDRHIINDENSRMSWDHKHYPFDAWNKEQNLN
                     TAMQNSVNWYFERISDQIPKNYTATQLKQLNYGNKNLGSYKSYWMEDSLKISNLEQVIV
                     FKNMMEQNNHFSKKAKNQLSSSLLIKKNEKYELYGKTGTGIVNGKYNNGWFVGYVITNH
                     DKYYFATHLSDGKPSGKNAELISEKILKEMGVLNGQ"
     CDS             12612..12992
                     /gene_functions="resistance (resist) blaI (Score: 275.2;
                     E-value: 3.8e-85)"
                     /gene_kind="resistance"
                     /locus_tag="ctg1_17"
                     /transl_table=11
                     /translation="MANKQVEISMAEWDVMNIIWGKKSVSANEIVVEIQKYKEVSDKTI
                     RTLITRLYKKEIIKRYKSENIYFYSSNIKEDDIKMKTAKTFLNKLYGGDMKSLVLNFAK
                     NEELNNKEIEELRDILNDISKK"
     CDS             13256..13849
                     /locus_tag="ctg1_18"
                     /transl_table=11
                     /translation="MKIGYARVSTGLQNLNLQEDRLNTHGCEKIFNDHMSGSKSKRPGL
                     DKAIEFARSGDTIVVWRLDRLGRNMEDLITLVNELNERGVSFHSLEENITMDKSSSTGQ
                     LLFHLFAAFAEFERNLILERSSAGRIAARARGRYGGRPEKLNKQDLNLLKTLYDNGTPI
                     KTIAEQWKVSRTTIYRYLNKLEDKEDEKQGEVSN"
ORIGIN
        1 cctatttaat gcaatcaatt aaagctgaac tagaagaaat acatacgttg aatatgcgcc
       61 gtcaaaatat gccgaaatac aatatattta atgaataatt caaataatct gataacaaca
      121 aagagaattc atcggttaaa tcatcaaaaa atagaagttt tgtaatatgt taagtgtgtt
      181 tatctttggg gttttaccta tatttgtttt gattgctatt ggtttcttga actcttttta
      241 ataaacattc ctgcgatata gttatcgatt aaaccacaaa atcctataat ttctgtgttt
      301 ttttcgtata cgataatttc tgccgttttg aaagattcta taacattatc gtaattatta
      361 acccaatatt cttcgttaat aaaattatgg gttgctatat tagaatttag ccagatactt
      421 cctaaagttt ttaaaatttc ttggtctttt ttatttaatt tacgtatcat tttttatcac
      481 cttgattttg aaacgagttg aaaacgagtt tcttcttgtc ttgatgactt tagccattgc
      541 gaccttcgtt gaaggtgcct gatctgtaat tatcttttga ggtttaccaa attgtttaat
      601 gagacgtttg ataaatgcat atcttagata gtagccaacg gctacaatga taacatcctt
      661 gttaaattgt ttatatctga aatagttcat agagaaaact cctttttgtt aaatttatac
      721 tataaattca actttgtaac agaaccttag taagcaaaca atttttaata acattaaacg
      781 actaatataa aaacgataaa gcaagaaaac tcttcatata tcaaagaaga tgccgacata
      841 gaaaaagtta ttcaaagagt aaatgcaaat aaaagaaata tggctttgaa agtacaacga
      901 gcactgaaaa aagcaatgat tcagataata ctaattctaa atttgaaaat tatattcaat
      961 taatagaaac acttaaaaat aaaatatcta ttttaaataa taaaattcaa aaacaggaaa
     1021 gttgtcacaa aatgacaata gaattttata ggaaagaatt acaggaaagg tcgaagctac
     1081 ttaaaaatca gcaaatattg actttagaaa gtaataaaaa aattcaaaat tggagtacaa
     1141 actagaagaa gaaaagtaac ttaactatac atctaagttt gatactagta ataaacagac
     1201 caataatgta caaaaagcta cttttaatga aaaagatgag aaaataaaaa acaaatagca
     1261 aaagaaaatg aattctttaa ggatgataat aaatatgaaa aaacaagtaa taattctgtg
     1321 aatagtttag taaaagaacg taaaaaagtt tttaaaaagt attttcggtc ttttagtgta
     1381 atttttcatt ttggatggat attgaaaaaa gcaatgttta atgataattt aagatgttaa
     1441 tatataagta agggagaagt gttgaataat acatattaaa atataggtat tataaaagtt
     1501 caaatgaatg gtgaagagat ggtgtcaaac gcttctgttg ttttttggaa aaaaaacttc
     1561 taattattac agcagctcat agtgtttttg attggcatta taaaaaattc gcagaatcta
     1621 tatctttttt tgactatgaa ggaaatgagg ttaatatcaa cagaattgtt ctaagtaata
     1681 attgggttag tgaaggtatt ttggattttg atactgctat attaattcca gataaaacaa
     1741 atgactgcaa ttacaataag atatatccaa aattctttta tgataaagaa caaaaaataa
     1801 ctgttttata tttgaaggac aaattattta aaaaaaatta atgtgtcatg aggctaatac
     1861 tttcgaagac tatatatacg aatcgagtat gattggtgta aatctaaaag ctaaagaagg
     1921 ttactctgga tctccttggt actataaaga tgaaaaagga acatatcaaa taacaaatac
     1981 aagcctctct tttaaaaaat ataaaaaatt aacatttgct ccatactggg gtatgcatat
     2041 gaaagatatg tttctatttt ctgaaaatgt aaacaatgtt aatgaaaaat atattaatca
     2101 tatattatat taggaggtga aataatgaat aaaaatagtg tcctaaaatt acaaggtata
     2161 cgcacaaaaa aatctacaaa tagccaagca tcaaatgcca gtgttatgtg taaaaaacag
     2221 agtagtgtaa gtgttgtttt ctgtgtattt ccacaaggaa ataaataaca tttaattaaa
     2281 aagcatcaac tgaaacatca gttggtgcta atttggagtt gttaagtgtg gattatagat
     2341 atgtaaaata tataaataat agtcggtatt atacaaaacc ttcttatgaa aatgaaggca
     2401 ttataaattt gaaacaagtt cctcataatt ttgaaatagt ccaaggagaa cattggacaa
     2461 atgttttcaa taatacacaa catctaccta aacaaggatg gaaaatacat atatgtacac
     2521 aactgaaaga ggctagaaaa actttagata tagtttctaa tcttatgttc aaagaaaatg
     2581 tatcttttaa atatgtaaaa agtatgcacg aattgatgtt aaaagattca aaatatggag
     2641 atcggagttc ttcggggaag tttattacta tttatccatc ttcaaatgaa caattcatag
     2701 atttattaaa aaaattggaa catgagctat ctaatcttcc taaagggccg tacattttaa
     2761 atgataaaag atggtataaa agtaatgtct attttagata tggtggtttt atgcctagga
     2821 cttttagata taatggggag atattagatg ctatagaaga tccaaatgga aatcttatag
     2881 aagatcaaag aaagccctat tatgtattac ctgattttat tgaggaaccc gaagaaataa
     2941 aaaaaatgaa tttggaagtt gatcatgaat ataaaagaac tcctttagat aactacaaca
     3001 taaaagaggc tctgcatttt agtaatggtg gtggggttta tttagcggaa cataataaat
     3061 ggggtaatgt tgtgttaaaa gaaggtcgtc cacacacatc gacaggcttc gataatattg
     3121 atgcttttga aagagttgaa aacgaaggga aagtattgaa gaagcttatg aaagcaaatt
     3181 atccagccaa aatatatgat tctttttcag cttgggagca taaatttatt gtagaagaat
     3241 atatcgaagg agattctttg tcgatttgga tggttaacaa atatccattt tcatcagaat
     3301 ctaataatga aaattatgta aaatcttcaa ttaatatctt aaatcaatta attaaagcta
     3361 taaaagaact ccacaattta aatataggtt ttggagatct tcaaccagct aatattatag
     3421 taagtaagga agaaaaaata agattaatag attttgaaac tgcaggttct attaatgatt
     3481 cattatccag tgtaatgact cctggcttta taggtagtcc caaaatgaac aaaggccaag
     3541 gagactggtt tgctgtacta agaattgcta agcaaatgtt tattcctata ggaagcgtcc
     3601 aagatatttc tcataatttg gacagtgttc ataatagttg gattaaatca acttttggac
     3661 aagaagcttt acatattata aaaaaaatag aaaatatatg caaatatcaa aattctagac
     3721 caatgaaaga atttatcact tctcaaaata aaacagtcag aaattttaat ttactatctg
     3781 ttaaagaaaa acttataaat tgtataaaga atgatctaag agatgaagaa ttgcttatgc
     3841 atggagatat aagacagtat gaaatgaatt ctggtaagtg gaatgttttg actggtggat
     3901 ttggtgtgat tatggcggtt aaaagatctg gagaatggga tgaaaaattt gataaatgga
     3961 ttaagagtat agattactcc aatttggggt atttagaaaa tgggttatat actgggaaaa
     4021 taggtatagc aaatgtacta atagaatctg gatatataaa agaagcagca acaataatta
     4081 aaactattaa tattgaagat agcaaccaag atatttcatt ggcatcaggt ttaagcggtt
     4141 taggtttttt aagtatatat tatgagctta aagaaaatat ttatttagat gaaagtaaaa
     4201 aaataggtga aatgcttgag aataacttcc aagataatac acctgtgtat acttttgatt
     4261 atgatatagt tgataaagga ttcctaactg gttggtcagg tgcttcttta tttatgtcat
     4321 gtttatatag agcaactaat aacgaaaaat ggttacatct ttctcgtaaa atgttgaaca
     4381 aagagttaga aaagacatta tttgatgata ctggattatt tcaagtagat gacgattttc
     4441 gtatactgcc ttatctatct agtggtggcg ctggtttagc aatacctatg attgcatatg
     4501 aaagtatagt aaatgaatcg atatggagaa aagagttaga aggtatatca aaaatagcta
     4561 aaagtaaaac atttttcaat ggaggattat ttcaaggtac taccggtata gtagctataa
     4621 gtaatttatt agataactat ttaaataaag aagatttgac taagtcttct ttatttacat
     4681 taaatttaca tttaattgaa acagaaaatt gtatttattt accaggagat tcatgtttta
     4741 gggtttcatc tgaccttatg tcaggaactg caggattgtt aacagttgtt gacgatatta
     4801 ttaataatag ttatttttca tggttacctt tacttaatat agacaagctt ataaatttag
     4861 ataaaattac aaggaggtga agttggtata tgaaaaatgt attggattta cagcaaatga
     4921 gaagcaaagc tggtaaaaag aagccaacaa gaaaacaatc tagtactagt tggggatgtg
     4981 ctccttctag taacactagt tggtttttct gttaattttg tgtgatattc ctgattaagg
     5041 aggtgagtta actatgaaca aagtattatc tttgcaacaa gaaacagttt caaaagaagt
     5101 acaattaaaa gctaaatctt caaaaagtca aaactgtaag aatagtagtc attctagctg
     5161 gtttatttgc tagaaattaa aagaggcaat aagatcgtat taaaaatact atcttattgt
     5221 ctcaattttt atggagttgt ttaatttgaa cgtatacaat attttaaaaa tagctattga
     5281 taataaaagc aagaaaattt atttggcagt tataattatc atttctttaa ttttcacatt
     5341 agcttcttta tatttccctt taataataaa aaatattata acagaacttg aaaaaaataa
     5401 agtgagtgtt tttattattt gctatttaat tttgttttta atattaaggt cagttatgga
     5461 atctataaat gagtatttaa tagctaaact tggaaatata gttataaaag acttacaaca
     5521 aaatatttat gatcgaatag taaactatcc aatatcattt ttcgatgaat ataatagtgg
     5581 agacttatca agtagactag taaacgatac agaagtaatt aaagatttaa taacatttca
     5641 tattcctaaa gttattaatg gattagttat gattgttggg gctgtttgtt taatagtgtt
     5701 attagactgg aaattgacag tactaatttt acttatatct cctgtaatat ttggaattat
     5761 atttccatta atgaaaaaat tagaaaatac aggagagata caacaaaatg aaatctccaa
     5821 ttttatatca aaaactcaag aaacatttaa aaatattagg atggtaaaag cttctactgc
     5881 agaacaatct gagagtaaaa gcatttctag atacataaat aatttattta aagtaaattt
     5941 atatgaaagt aaggttatgt ctttagtatc tcctttagtg aaccttttac ttatttttgg
     6001 cttactaatt atagctggat atggcgcata tcgaattcaa aatgatactt taactttaag
     6061 tactcttatt gcatttataa tttactcatt ccagttaatg agtcctataa gttcaataag
     6121 tagttttata ggagaatatc ataaatctaa tggagctttt aaaagcttaa ctgttatcct
     6181 tagtaaggat attgaaaatg ctaaaaatac atataaatat aattttaagt tagaggataa
     6241 attaatattt gataatgtaa gtttagaatt taaagaaaaa aaaatccttg ataatatctc
     6301 ttttaaatta aataaagggg agtctcttac aattataggt ccttcaggat ctggaaaaac
     6361 aacattatta aatgtaatag aaaaatttta ttatataaac agtggaagta taactataga
     6421 tggtatagac attaatgata tcaacactca aaatttaaga tacaatatag gattagttag
     6481 ccaagatata cctattataa gtggtacaat aaaagataat ttactatatg gattgaataa
     6541 tgtaagtatt accaattttg aaattaaaga tattttaaaa tctactatgc taaaggatct
     6601 tgttattaat caaattgatg gtattaatag ttatgttgga gaaagtggta atcgtctttc
     6661 aggcggcgaa aaacaaagaa ttaatatagg gagagtactt ttaaaaaatc ctaatattat
     6721 tttattagat gaagcaactt caaatctaga taatgaatcc aaatctgaaa ttattaactc
     6781 tatatctgaa ataacacaag ataaaactgt tttaaaaata acacacaata tgcatgagtt
     6841 aaaagaagac gaacaaatat tatttataga aaatgggaaa attattttta aaggaaaaca
     6901 tggtgagttg ctgaaaaaca atgaaagata taaaaaattc attaaaaatg aggcttagta
     6961 ctttacctat agtttaaaat aaggtattat actatataca gtagttagta taacttatat
     7021 gagaggggca ttatttaatg aatattcaat ttaaaaaagg cgccttggaa ttattagttt
     7081 tattaattgt aaaacaggaa gatcaatatg ggtactcatt aagtcaaatt ataactaata
     7141 ggatagctat atctgagggt actatatatc ctttgctacg taagcttgta agagaagaat
     7201 atttggaaag ttactatacc ccctctaaag aggggccttc gagaaaatat tatagtataa
     7261 ctagtaaagg taatgtacgt ttaaatttac tactcagaga atggaacaac tttactgaag
     7321 caataaatat gtttgtgaaa gagagtggtc ttcatgaata aagaagagta tttaagaata
     7381 attaaaaaag gaattaagaa agtagatgct aaggaaaaag aagatatttt aaatgaatat
     7441 gaatcgcatt ttattagtgg atataaagat aataaggatg atacggaaat tattaaagag
     7501 ttaggtaatc ctataaaggt agctaaagag ataaatgctg taaattcaat atataaaata
     7561 gaaaaggaaa aaagtgttaa aagcatattt tctgcagcat tttctattat gggacttagt
     7621 atcttcaact tatttttaat aataattagt ttttttattt ttttattact cttacctttt
     7681 gtactagctt actttattgc agttccaata atgatttttt caccaataat attattagta
     7741 atgggttgta taaatggctt tgacactatt aatacaggag acattttcga agttattaaa
     7801 ggggtagttt taggaattat attagccttt attggttatt ttattgctaa atatttcttg
     7861 aaacttttgg ttctttattt gaattggaat atagatgtat ataaaaagga gaaattaaag
     7921 tgaaatatat atatatatat ttattattga ttttttcaat tattttagtg agttgctcta
     7981 attctataga taataataat tctaaggaaa atagcgaaga taaaatagta gaaaaaccat
     8041 tacctaaaaa aatatttgat aagaataaag atggacaata tataacagaa aatgaaatta
     8101 gaaaatcaat aaaactgtat ttagataaaa atgaagaatt atctgaagct agtgaatact
     8161 atgaagataa aatagattct gaagaatcgc tgagtcaaaa tgaaattaaa aaacttaaga
     8221 agttaaataa tttaaatcaa aaaaatgatg aaaattttaa aagctatata aaaagcaaca
     8281 aattacctaa aagttacaga aaagacacag aaagaataag taaatacatt tctcattcta
     8341 ataaatattc ccaaaatttg gaaaagaaaa ttgataaaat aatagacaaa ggtataaatc
     8401 aaaaaaagta tcaattaaag atattggaaa aatcgaaaat gatagtacaa tagtgaatgg
     8461 aagagagcaa tctaaaatag aaaaattctt aaatgaaaaa aatattaaaa ctaaagcctt
     8521 taaaaagtaa ttacttattc atcaactttt tatttttaca gttagaatca caataattta
     8581 aatcacaaac cacccgtgtg aacgggtggt ttgttctacg tttataaacc tcttttattg
     8641 gccagcccaa aaggacactg acaggtcagt caactgcact actttcccat cacaccccct
     8701 aaaagggtac tatttttttc gtcttttttt aatttcttct cctgtaaatg gacctatgta
     8761 ttcttctatt gaaatttgat ctgcaacgat attctcttgt aattgattac gaatgtaatt
     8821 ttcaattacc tttttattgc tacctactgt atctacataa aatcttttac accaaaacta
     8881 tctatttcca tatctatatt ttaaattgac ttgtctatca aaaattatta aaatactttc
     8941 accttttaaa tatccaacaa ataatgatgc tcttcattta ggtggaatac tcactaacat
     9001 atgaatatga tttttacatg cttctcctta tattatttct atgccttttc cttcttctaa
     9061 catttctgca actcgataat agataatacg tttttatgga tttttagcgt taggagaata
     9121 caataaaagg tgccctttat atacaccttt ttctttcgca acttgaatac cttgtgcttg
     9181 tctacgttta ctttcatttc gttcttgttc tgaaaccatt gctagtattt gaatgattag
     9241 gtctttcata aatttatcta ataatggatt accgatcact tcattcatca taggtaagct
     9301 agtaatcatc aattgaactt ctttatcttt taaataatta actgtgttaa tcacctcatc
     9361 ataattacga cctaaacgat caatggattc tactataaat cgatccccca ttctcacaaa
     9421 gttaagtgct tcttgaagta ccggtctatt ttcaatagat ttcccatact gtttttctgt
     9481 aaatattttt tcagcaccaa acgtctttaa attttcaagt tgcctttcta aattttgatc
     9541 gattgatgac actctcgcat aaccaataat cattgatttc acctcataat taatatacac
     9601 cctaatcata cgtttaagtt acttgtcact ttgcttgata tatgagaatt atttaacctt
     9661 ataaatgaga aaaaagcaac gcactttaaa taagatacgt tgctttttcg attgatgaac
     9721 acctataatt aaactattca tctattattt atgatttttt gtatatacaa tatttctagt
     9781 ttgttaaaga gaattaagaa aataaatctc gaaaataata gagggaaaat cagtttttga
     9841 tataaaaatt atacatgtca acaataatac aaactataag atgatatcag tatttattat
     9901 gcatttagaa tattaaaatt ccttcattac actcttggcg gtttcactta tcaacttatc
     9961 atttggctta tcacttttat tgtctttatt cgtaaaaatg actaaaacaa taggttcaga
    10021 ttggccctta ggataaacaa aagcaacatc atttctagaa gcatatgtta ttgcttgacc
    10081 acttttatca gcaaccttat agtcttttgg aacaccatct ttaattaaag tgtctccgtt
    10141 tttattatta aacattaaat caagtaagaa atttttattt tttttgctta attttccatt
    10201 tgcgataagt ttatttaaag tcttgccgaa agcagcaggc gttgaagtat cttttttgct
    10261 ctttggtgaa tagtaattta attctatctc atatctaact ggatttgtta ctttatctcc
    10321 tagttctttt agatgttgtt taactttttt gattccaccg atttctttta taattttatt
    10381 gtttgctgta ttatcactat atgtcattga agcctcaata agttctttta aagtgatatc
    10441 ttttcctaca tatttttcta aaataggaga ataagcaact atatcatctt tgttaatatg
    10501 tattttttta tttaacttat tataaggtac ttgttctaac aaaatagcac tatttatcgc
    10561 ttttgaagtc gaagcatagg caaatctctt atctgaatta aattttactt ccttaccact
    10621 tttagtatct aaagcataaa caccaatatg agcattatat tttttttcta aatcatttaa
    10681 ctcttgggta tgtgaactgt ttgaattaca tgcacttaaa actaaagcaa ttacaattaa
    10741 aaatattaac tttttcaaaa taaaccctcc gatattacag ttgtaatttt tataaatcaa
    10801 taatattaca attgtaatat cggtgtcaat agtttattat aaatatttga aagaaggtgt
    10861 tgaaatggct aagttattaa taatgagcat agtaagcttt tgttttatat ttctattgtt
    10921 attatttttt aggtacatat taaaacgcta ttttaattat atgttaaatt ataaagtttg
    10981 gtatctaact cttcttgcag gattaattcc tttcattcct attaaattct ctttttttaa
    11041 atttaataat gtgaataatc aagcgcccac agttgaaagt aagtcacacg acttgaacca
    11101 taacataaat accaccaaac ctattcaaga gttcacaaca gatatccata agtttaattg
    11161 ggattcaatt gataatatct gcacagttat ttggatagtt ttagttatta ttttaagttt
    11221 taaatttttg aaagccttat tatatcttaa atatttaaag aaacagtcac tttatctaaa
    11281 cgaaaatgaa aaaaataaaa tagatacgat acttttcaac catcaatata aaaaaaatat
    11341 tgtgattcga aaagcagaga ctattcaatc tccaataact ttttggtatg ggaaatatat
    11401 tattttgatt cctagttcat attttaaaag tgtaattgac aaaagactaa aatatataat
    11461 attgcatgaa tatgctcatg ctaaaaatag agatacttta catttaatta tctttaatat
    11521 cttctctatt attatgagtt acaatccatt agtacatatt gtaaaaagaa agataattca
    11581 tgacaatgaa gtagaagccg atagatttgt ccttaataat attaacaaaa atgaatttaa
    11641 aacttatgcg gaatctatta tggactccgt attaaatgtt ccatttttta ataaaaatat
    11701 attaagccat tcatttaatg gtaaagagtc attactcaaa agaagattaa ttaatataaa
    11761 agaagccaat ctgaaaaaac agtccaaatt aattctaatt tttatttgta tttttacttt
    11821 tttgctcatg gtaattcaaa gccagttttt gatggggcaa tccataactg attataatta
    11881 taaaaagccc ttacacaacg gttaccaaat tttagataaa agtaaaattt ttggttcaaa
    11941 tagtggatct ttcgtcatgt acagcatgaa gaaagacaaa tactatattt ataacgaaaa
    12001 agaaagtaga aaaaggtatt ctcctaattc aacttataaa atttatttag ctatgtttgg
    12061 acttgaccga catattataa atgatgaaaa ttcacgtatg tcatgggatc ataagcatta
    12121 cccttttgat gcttggaata aggaacaaaa tttaaataca gcaatgcaaa attcagttaa
    12181 ttggtacttc gaacgtatta gcgatcaaat accaaagaac tatactgcga ctcaactcaa
    12241 gcaattaaat tatggtaata aaaatttggg aagttataaa agctattgga tggaagatag
    12301 tttgaaaata tctaatcttg aacaagtaat agtttttaaa aatatgatgg aacaaaataa
    12361 ccattttagt aaaaaagcaa agaatcaatt atcttcttca ttattgatta agaaaaatga
    12421 aaagtatgaa ctgtatggga aaacaggtac aggtatagta aacgggaagt ataataatgg
    12481 gtggtttgta ggttacgtaa ttacaaatca tgataagtat tattttgcta cacatttatc
    12541 agatggaaag ccatctggga aaaatgctga attaatcagt gaaaaaatat taaaagaaat
    12601 gggtgtttta aatggccaat aagcaagttg aaatatctat ggctgaatgg gatgttatga
    12661 atataatatg gggtaaaaaa tcagtatcag ctaatgaaat tgtagttgaa attcaaaaat
    12721 ataaagaagt tagcgataaa acgattagaa cattaatcac aagactatat aaaaaagaga
    12781 ttataaaacg atacaaatca gagaatattt atttttactc atcaaatatt aaagaagacg
    12841 atattaaaat gaaaactgct aaaacttttc ttaataaact gtatggaggg gacatgaaaa
    12901 gtttagtgct gaattttgcg aaaaatgaag aattaaataa caaagaaatt gaagaattgc
    12961 gagacatttt aaatgatatt agtaaaaagt aattagagat atgtttcaaa cataatacat
    13021 atgtaaacta tgcttgactc ttattaaatt agttttgtta ataacattta aaatatatta
    13081 ttaaagatga gagtgtacag aaaataacca ttttctgtac actcgttttt tatgtctaaa
    13141 taagtatgta ttacatagaa ttatgtgttc aaaaacccaa caaaaaatct atgttcacaa
    13201 aagaccttgt gattaagtta tggtacactg aaggtgtata taggaggttt gtattttgaa
    13261 aataggttat gcaagagttt caactggatt acaaaattta aatttacagg aagatcgatt
    13321 aaatacacat ggttgtgaaa agatatttaa tgaccatatg agtggttcaa aaagtaaaag
    13381 acctggttta gataaagcaa ttgaatttgc gaggtcagga gataccattg ttgtttggag
    13441 actagataga ctaggacgta acatggagga tttaatcaca ttagttaatg aacttaacga
    13501 acgaggcgtg agttttcata gtttagaaga aaatataacg atggataaat caagttctac
    13561 aggacaatta ttatttcatt tattcgcagc atttgcagaa tttgaacgta atttaatttt
    13621 agaacgttct tcagctggcc gaattgcggc acgtgcaaga ggaagatatg gagggaggcc
    13681 tgaaaaatta aataaacaag atttgaattt acttaagacg ctttatgata atggcacacc
    13741 cattaaaaca atagcagaac aatggaaagt ttcacgtaca actatttatc gttacctcaa
    13801 taaattggag gacaaggaag atgaaaaaca aggagaagta tctaactaat ttttctgaag
    13861 ccaaacgtaa agaagctact caaaagtaca atataataaa accttttatc ttgggaaatc
    13921 aatctttatc aagtatttct aaaaataagg acattgcatt aagtacactt tataggtgga
    13981 ataaattata taaggaagaa gggcttactg gtctaattca taatacaaga gttgataaag
    14041 gtgatcataa attagaacaa aacataattg acgagattaa acgcctttca ctcaagaata
    14101 aaagaaatag tattgctaca attcatagga aaatcgttaa ttattgtata gaaaataatt
    14161 ttgataaacc aagctacaaa caagtttata gtattattaa agcaatgcct aagtctgtta
    14221 ttgatttctc tcaccaaggt gaaaaatact atcaaaataa gtacgattta atacaaataa
    14281 gagaatcctc aagacccaat gaaatatggc aagccgacca tactttgcta gatatttata
    14341 tattagatca aacaggtaat attaatagac cctggctaac cattattatg gatgactata
    14401 gtcgcgcaat tgcaggatac tttataagtt ttgaagctcc taatgctcaa aatacagcat
    14461 taacactaca ccaagcaata tggaataaga ataataccaa ttggccagta tgtggtatac
    14521 ccgaaaaatt ctacacagat cacgggagtg actttacctc gcatcacatg gaacaagtcg
    14581 ctattgattt gaaaattaac ttgatgtttt caaaagttgg tgtccctcgt ggtcgcggga
    14641 aaatagaacg tttttttcag acagttaacc aaactttctt agagcaactt cctggatata
    14701 taaacaataa tgatactcct agcgatttaa tagattttca aaatttcgaa gaaaaattac
    14761 gatacttttt aattgaagat tataatcaaa aagagcatag tgctatccag agcactccta
    14821 tcaatcggtg gaacagtaat cattttttcc ctaatatgcc aagcagttta gaacaacttg
//
