LOCUS       NZ_CP044277.1           7626 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP044277.1 Enterococcus faecium strain V2937 plasmid
            pHVH-V2937-3, complete sequence.
ACCESSION   NZ_CP044277
VERSION     NZ_CP044277.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-06-07 21:33:20
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 7626
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..7626
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2251:2626]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2252..2626
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..7626
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..7626
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             complement(138..1286)
                     /gene_functions="other (smcogs) SMCOG1192:transposase
                     (Score: 399.5; E-value: 2.4e-121)"
                     /gene_kind="other"
                     /locus_tag="ctg1_1"
                     /transl_table=11
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYEE
                     VKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRFKS
                     KKNPVQSYTTNNQNGTVALIDSKFIKVPKLKSLVRIKLHRQPKGIIKSATISRHSSGKY
                     YISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDNNKFTSKMEKKLKREQRKLS
                     RRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLNKLSTEMIKNHDIICIED
                     LNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIKVDKWFPSSQICSECGHKD
                     GKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLHSMGLA"
     CDS             complement(1303..1707)
                     /locus_tag="ctg1_2"
                     /transl_table=11
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERISE
                     SYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLWKEMF
                     WSKSFCLLTTGGAPIDVIKKYIQNQGNNHK"
     CDS             complement(1793..2119)
                     /gene_functions="other (smcogs) SMCOG1148:hypothetical
                     protein (Score: 63.7; E-value: 4.4e-19)"
                     /gene_kind="other"
                     /locus_tag="ctg1_3"
                     /transl_table=11
                     /translation="MEDLGSKLRELRVKKGYTQEYVARKFNVTRQTISKWENNKTTPDI
                     ETLKKICEFYSTNINSILNEDNSKNKKNNLLVLTAIIFNRIRQKSPILYRWVMNAVRYE
                     GYRW"
     CDS             2252..2626
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Lactococcin_972"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_4"
                     /sec_met_domain="Lactococcin_972 (E-value: 2.3e-09,
                     bitscore: 28.1, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKFLCLSALMGVLLTSGGIASATEALNLDVPEDHTAIYGGGMEA
                     TEEGFSSSKLRYAAGGGDFNCGVNGFKVYANYYHARAKHSATAKNGRGGQVRSVQKAGV
                     RAYATCNATLTGNTGWWNVY"
     CDS             2680..4566
                     /locus_tag="ctg1_5"
                     /transl_table=11
                     /translation="MLKKINAVLSLFVCITILFFSTNVINGIKTSEALYKNTAEIHMQY
                     KDDMDFNSYINALYEISTQENINISQYSFTAVNQLTILATNPNANKHWKFSKKNILARN
                     DSKVHYTNNKNSKYQLKLPNNFLNINIYPFSHVENIGLSEILYVQGNSNKLIPVLKKYG
                     TPTISNINQSDTFQINTNIVLVICYLSIFIVITTIIFAFSKMKEITLKKMLGYNSFDTI
                     KDSIKELNLLFCSLIITFILSIFLSIYYSNENFFLSFLLCSIFHFIISFLFIIVTLSIY
                     HLSSIKNYLKNSRPLKLNLCILNICLFLSMILLLIASTKVINTHNEAENNSLKYWERTT
                     NLYKTNITNQLNRNNTVEENNYLKKASKFVYKIQKNYKTFIIAPYNYATIQENNKEFFI
                     GQKVYPNFEDYVSQPAGAGICVDLNYLKYYNPISFEESTDLNLINSDPLTTYILVPKKY
                     KEYAKMIEKNYLEDIQFRLEDSPPQAPYKNPNLKNLKIKLIFVNNNQKYFSFNTLYGKA
                     KDNYTITDPIVRVINPEITESLFWGNILTSDGGLFFDQKHTSNQNFFNQINPYIKEFNL
                     ENIINFSYSVFQETGELLSQKKVNKLNAYLQVKSRLLCKMLYNVFTISTYQN"
     CDS             complement(4550..5722)
                     /gene_functions="other (smcogs) SMCOG1130:transposase
                     (Score: 402.6; E-value: 2.3e-122)"
                     /gene_kind="other"
                     /locus_tag="ctg1_6"
                     /transl_table=11
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTEY
                     IQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKALM
                     ASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKNYPY
                     LMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEYLKER
                     GLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNIFTTIPKKNSKSFREAVKGI
                     FKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDGFEDAFQYTVQGNSHNRLKSTNLI
                     ERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK"
     CDS             5785..6138
                     /locus_tag="ctg1_7"
                     /transl_table=11
                     /translation="MAFLLLHNYTDFIYLQYLLILGLFIIINFQMIFVSFTINSKKIAL
                     KKIFGYSPISQVLDLCLLPFTIELFATMCFQLIFSKNTYLYFIIFMIFLINLITSIIIY
                     KKNSFKYFKENIL"
     CDS             6135..6755
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 136.7; E-value:
                     1.7e-41)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_8"
                     /transl_table=11
                     /translation="MILSVENFTLSINKKKIKQNWNFSISEKDFIIVTGKSGSGKTTLL
                     NNLSLIDKQYTGNLFYFEKKVSKHDIQRLRRNHISYLFQNYALLENQTVQYNFELAKKF
                     NSNISNDHIYNLLTDFSLPKDILKEKIFLLSGGEQQRIALIRNMLKPFDILFADEPTGN
                     LDKENSTFIMNFLKNLTEKEKKAVVLVTHDLNVLNYGTNIIEL"
     CDS             6869..7006
                     /locus_tag="ctg1_9"
                     /transl_table=11
                     /translation="MILLKKEYEKFYDRLIYSLQLPKKLNRQLQKTYETKSTEEWESYC
                     "
     CDS             6966..7127
                     /locus_tag="ctg1_10"
                     /transl_table=11
                     /translation="MKLNQLKNGRVIARFLVEVTKSGHIIIMTRRKSDKKLAKNIAECL
                     IKLSVLAK"
ORIGIN
        1 aacctgacgg ttcttaacgc ttgaagtggg agcttcttgg gaatagagca tacttgatag
       61 cgtatttctt tactaacagc ggtgtctctt atttaccaag ctatccccgt agttcctacg
      121 gttcttgatg attggatcta agccaatccc atagaatgta gtcttagacc ttcggtcaga
      181 atattgatac tagcattgat atcacgatca tgatgagtat gacaaacagg acaagtccat
      241 tctcgaattt caagagattt cttgccatct ttatgtccgc actctgaaca aatctgacta
      301 gacggaaacc atttatctac tttgatgatt tttcgtccat accagtcagc cttgtattgt
      361 aatttagtca caaactttga ccaagaaaca tcagaaatac ttttagctaa tttatgattt
      421 cgcaacatac cttttgtgtt taagtcttca atacagataa tatcgtgatt tttgatcatt
      481 tctgtactca acttattcag aaaatcagta cgttgattca ttactttttc atgcaatcta
      541 gctactttgc gtttttgttt ttgataattt ttagcttcaa atagattggt acctttattt
      601 ttagccaata aagcacgcct agacaatttg cgttgttcac gctttagttt cttttccatt
      661 ttggacgtga atttattatt atcaattttt tgtccatcag aaagaatcgc aaagtccata
      721 atacctaagt caataccaat tgtggaatta gttttaggta attcgataat ttcttcttta
      781 cacaacaaag aaatatagta tttaccgcta gaatgacgtg atattgtagc agatttgata
      841 atcccttttg gttgtctatg aagcttaatt cttactaatg acttcaattt aggaactttg
      901 atgaatttac tatcaatcaa agcaactgta ccattttgat tattcgttgt ataactctga
      961 acaggatttt tcttactttt gaaacgtgga aatccaacgg atttatcccg aaaaaaattc
     1021 ttgtatgctt tatctaaatt aagttgggca ttggctaaag caaggctatc aatttctttc
     1081 aaaaacggaa attctttctt gtatttagct ggtgtcggaa aagtcatttt tttagaagaa
     1141 tcatttttaa cttcttcata cgcctttttt cggtcatcaa gcattagatt gtagacctta
     1201 cggacacaac caaaagattt ggcaaagaag atttcttgtt cctctgttgg atagattctg
     1261 aatttgtatg cttttagttg ttccataaag ttcacctact ttctatttat gattgtttcc
     1321 ttgattttgg atatacttct taatcacatc aattggtgcg ccaccagttg tcagaagaca
     1381 aaaactttta gaccagaaca tttctttcca aagaaattgt ttgactcttg gaaagtcacg
     1441 ttttatcaat cttgagctgg cacttttata ggcattgatg aattttgtca attctgtttt
     1501 aggttgagct ttgaacataa tatgaacgtg gtctttatca tgattccact ccactaaagt
     1561 aatgtgatac gattctgaaa ttctttcaaa agtagttttg gcataatcag atatttcatc
     1621 atcaatcact tgtctacgat atttcgttac taaaacaagg tggtaataaa gaagaaatac
     1681 tgaatgatta tttgtatcta attccatgtt atatcaactc atttcttgta tagactgatt
     1741 gtaacatgga acaaaataaa aaggcaatac gccttagttg tcggtcttcg agttaccaac
     1801 ggtaaccctc ataccgaacg gcattcatca cccacctata gaggatgggc gacttctgcc
     1861 taattctgtt aaaaataata gctgtcaata ccagtaaatt atttttttta ttttttgaat
     1921 tatcttcatt taaaatagaa tttatgttag tactataaaa ttcacaaatt ttttttagtg
     1981 tctctatatc tggtgttgtt ttgttatttt cccactttga aatagtttga cgtgtaacgt
     2041 taaattttct tgccacatat tcttgagtat accctttttt cactcttaat tctcttagct
     2101 tagatcctaa atcctccatt ttttctccta tgtaaacgat tatttacata aaattttatc
     2161 ataaaaatac taacgcgcca aaaaagttct ttattttata aaacacacta aaataaaata
     2221 attctagtaa aaaagatagg agaaataagt tatgaaaaaa tttttatgtc tttctgcttt
     2281 aatgggtgtc ttattaacta gtggaggaat agctagtgcc acagaagctt taaatctaga
     2341 tgtacccgaa gaccataccg ccatttacgg aggaggaatg gaagctacag aagaaggatt
     2401 ttcttctagt aaattgagat atgctgctgg cggcggggat ttcaactgtg gggttaatgg
     2461 atttaaagtt tatgcaaatt actaccatgc tagagctaaa catagtgcaa cagctaaaaa
     2521 tggacgaggc ggtcaagtac gatcagttca gaaagctgga gtaagagctt atgcaacatg
     2581 caatgccaca cttactggaa atactggttg gtggaatgtt tattaaaaaa gagagtttaa
     2641 actctctttt ttatttacat ttgaaaggaa attcaaaata tgttaaaaaa aataaacgct
     2701 gttttatcac tttttgtctg cattacaata ctattttttt ctactaatgt tataaatggt
     2761 ataaagactt ctgaagcgct atataaaaat accgctgaaa ttcatatgca atataaagat
     2821 gatatggact ttaacagtta tataaacgct ttgtatgaaa tatctacaca agaaaatatt
     2881 aatatttctc aatatagttt tactgctgtt aaccaactaa ctattcttgc tacaaaccct
     2941 aacgctaaca aacactggaa attttctaaa aaaaatatat tagcaagaaa cgattctaaa
     3001 gtccattata ctaataacaa aaattctaag taccaattaa aacttccaaa taatttttta
     3061 aatataaata tttatccttt ttctcatgtg gaaaatattg gattaagtga aatattatat
     3121 gtacaaggaa actcaaacaa attaattcct gtactgaaaa aatatggaac acctactatt
     3181 tccaatatca atcaatcaga tacttttcaa attaatacta atattgttct tgttatctgc
     3241 tatcttagta tatttattgt aattactaca attatatttg ctttttcaaa aatgaaagaa
     3301 atcactctaa aaaaaatgtt aggctataac tcttttgata ctataaaaga ttctattaaa
     3361 gagttaaacc tcttattttg ttctttgatt ataactttca ttttatctat ttttttgagc
     3421 atatattaca gtaacgaaaa ttttttccta tcatttcttc tatgtagtat ttttcatttt
     3481 ataattagtt ttttatttat catagttact ctaagtatct atcatttatc tagtataaaa
     3541 aattatctaa aaaattcacg accacttaag ttaaatcttt gtatattaaa tatctgtcta
     3601 ttcttaagca tgatccttct gttaatagct tctacaaaag taataaatac ccataatgaa
     3661 gccgaaaata attctcttaa atattgggaa agaactacta atttatacaa aacaaatatt
     3721 actaatcaat taaatagaaa caacaccgta gaagaaaata actacttgaa aaaagctagt
     3781 aaatttgttt ataaaataca gaagaattat aaaactttta ttatcgcgcc atacaattac
     3841 gcaactatcc aagagaataa taaagaattt tttattggac aaaaagttta tccaaatttt
     3901 gaagactatg ttagtcaacc tgctggtgca ggaatatgtg ttgatttaaa ctatctaaaa
     3961 tattacaatc ctatttcttt tgaagaatct actgacttaa atttaataaa ctctgatcca
     4021 ctaactactt acattctagt acctaaaaaa tataaagaat atgcaaaaat gattgaaaaa
     4081 aattatttag aagacataca gtttagactt gaggactctc ctcctcaagc tccttataaa
     4141 aatcctaatt tgaaaaattt aaaaataaaa ctaatatttg ttaataataa ccaaaagtat
     4201 tttagtttta ataccttata tggaaaggca aaagataact atacaataac tgatcccata
     4261 gttagagtta ttaatccaga aataacagaa tcattatttt ggggaaatat attgactagt
     4321 gatggtggat tattttttga tcagaaacat acttcaaacc aaaacttttt taatcaaatt
     4381 aatccgtata taaaagaatt taacctagaa aatatcataa atttttctta ttctgttttt
     4441 caagaaactg gtgaattatt atctcaaaaa aaagtaaata aattaaatgc atatctacaa
     4501 gtcaagtcca gactcctgtg taaaatgcta tacaatgttt ttaccatttc tacttatcaa
     4561 aattgatgta ttttcttgaa gaataaatcc attcatcatg taggtccata agaacggctc
     4621 caattaagcg attggctgat gtttgattgg ggaagatgcg aataatcttt tctcttctgc
     4681 gtacttcttg attcagtcgt tcaattagat tggtactctt tagtcgattg tgggaatttc
     4741 cttgtacggt atattgaaag gcgtcttcga atccatcatc caatgatgcg caagcttttg
     4801 aatattttgg ttgatcgata taatcatgaa tcaatcgatt tttagcctca cgcgctaagt
     4861 taatatctgt gaacttaaaa attcctttaa cagcttctct gaaagatttt gaattttttt
     4921 taggaatggt ggtaaagata tttcttagga agtgaacttg gcatctttgc caacttacgt
     4981 tggtgaagga ttttctaatg gcagagacta atcctttgtg cgcatcagaa ataacgagtt
     5041 ccgtaccttg taaaccgcgt tcttttaggt attcaaaaaa tgttgtccag gtctcttcgc
     5101 tttcgccact ttgaatcatg aagccgataa tttcacggtc gccatctttg gttattccaa
     5161 tcgctatatg acagcttttt gagagtactc gattttcttc tcgtactttt atatagagta
     5221 catcggtcat taagtaagga taattttttt ctgataataa acgattctgc cactcgttaa
     5281 ccataggttc tagctgttct gttaagctag aaacgaagga cttagagacg gatttaccac
     5341 aaagttcttc cacaattttt gatactttac gagttgaaac gcctgataca tacatttcca
     5401 acattgaagc catgagggct ttttcgtttc gttgataacg ttcaaacact gtgggtgaaa
     5461 aatggccatc acgtgttctg ggtactttta attctagcgt gcctacacgt gtcgtaaagc
     5521 tgcgctcata atagccattt cgttgacttt gtcggttttc tgttcgttca tattcttttg
     5581 cttgaatata ttctgttcgt tgattttcca ttagttgatt aaataccgtt gttaaaatat
     5641 ttttagaaac gtcatccttt acagaatatt caataatgct ttgaatctct tcgcttttca
     5701 gtgtaaaatg tacttgggtc atgtaaaagt cctcctgggt atgtttttgt cgttaaaaac
     5761 attgtaccgt aaaaggactg ttatatggcc tttttacttt tacacaatta tacggacttt
     5821 atctatctac aatatctttt aatattagga ttatttataa taattaattt tcaaatgatt
     5881 tttgttagtt ttactataaa ttcaaaaaaa atagctttaa aaaaaatatt tggatattca
     5941 ccaataagtc aagttttaga tttatgttta ctccctttta caatagagtt atttgctact
     6001 atgtgttttc aattgatatt ttcaaaaaac acttacttgt attttataat ttttatgatc
     6061 tttttaataa atctaattac ttctattatt atttataaaa aaaatagttt taaatatttt
     6121 aaggagaata ttttatgata ttatcagttg agaatttcac cctgtcaatt aataaaaaaa
     6181 agatcaaaca aaattggaac ttttcaatat cagaaaaaga ttttattata gtaacaggaa
     6241 aaagtggtag tggaaaaact actctgttaa ataatttaag cctaatagat aaacaatata
     6301 ccggtaactt attctatttt gaaaagaaag tttctaaaca tgatatacaa cgtctacgaa
     6361 gaaatcatat tagctattta tttcaaaact atgctcttct tgaaaatcaa acagtacaat
     6421 acaatttcga attagcaaaa aagtttaaca gtaatatttc caatgatcat atttataatt
     6481 tattaacaga tttttctttg ccaaaagata tcttaaaaga aaaaatcttt ctcttaagcg
     6541 gtggagaaca acaaagaata gcattaatta gaaatatgtt aaaaccattt gatatattat
     6601 ttgcagatga acctacagga aatttagata aagaaaactc aacttttata atgaactttc
     6661 tgaaaaattt aacagaaaaa gaaaaaaaag ccgttgtact agtaacacat gacttaaatg
     6721 ttctaaacta tggaactaat attatagaat tataattttt acccgtgatg ctagctgatt
     6781 taaaactagc accacgggta tttattttat attccatctc tcctatccca aaatttaaat
     6841 aatcacttaa taaaaaggag gcaccctagt gattttattg aaaaaagagt atgaaaaatt
     6901 ttatgataga cttatttatt ctttgcaatt gccaaaaaaa ttaaaccgtc aattacaaaa
     6961 gacttatgaa actaaatcaa ctgaagaatg ggagagttat tgctagattt ttggtagaag
     7021 taacaaaaag tggacatatt atcataatga ctcgccgaaa gtctgataaa aaattggcta
     7081 aaaatattgc tgaatgttta ataaaactat cagttttagc taaatagtta gtagtttaca
     7141 caaaaaagca tttatgtttt ttgttgcaaa gtaacaattt catcttcggt gaaataagcg
     7201 aaactttaca aaaagtggct agcatttgct agcttttttt gtattgtgga gcgtggcttt
     7261 tgagggggat tcaaggggga gcttgcgccc ctttgacaag cggttatttg cactaaatac
     7321 gtaggtattt ggctagcaaa tatagagctt gccaaaccct tttagtgagc tttactcatt
     7381 gtaccttttt aggtacaatg gtattgcgaa cgatacgtcc gtaggacgta ctgaaagggt
     7441 gggacttatg agcgaacaaa atcaaaattt ggctagcaat tcttctaaaa aatataccta
     7501 tcgatccgag ccaaaacaaa tcagttttcg agtgagcgaa tccgaatttg caactctgaa
     7561 gctttgcaaa tgagtgtgcc ggctttcgtg aaagccaagg cacaaaacgc gcgtctggtg
     7621 acaccg
//
