LOCUS       NZ_CP033633.1          10885 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP033633.1 Escherichia coli isolate ECCNB12-2 plasmid pTB-nb2,
            complete sequence.
ACCESSION   NZ_CP033633
VERSION     NZ_CP033633.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-06-07 15:41:50
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 91570
            Orig. end    :: 102455
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10885
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:5885]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5885
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..10885
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10885
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             990..1442
                     /locus_tag="ctg1_109"
                     /transl_table=11
                     /translation="MKFMECAVRDVIYGTNVRLVKPVNIYECELGDNVFVGPFVEIQKG
                     CVIGSGSRIQSHTFICENVTLGEKCFIGHNVTFANDLFRSGAPDPSPDNWISITLGDSV
                     TVGSGAIILSPYICSGAVIGAGSVVVKPIENKGIYAGNPARLLRIL"
     CDS             complement(1474..1659)
                     /locus_tag="ctg1_110"
                     /transl_table=11
                     /translation="MMDSLFDFRIARIRILSGLGNDALGYLPKKGDITDAEYRAALEID
                     PRQSISVHLPYSQTYL"
     CDS             complement(1656..1838)
                     /locus_tag="ctg1_111"
                     /transl_table=11
                     /translation="MSRKTQRYSKEFKAEAVRTVLENQLSISEGASRLSLPEGTLGQWS
                     NLPIWPLLPHFRSMV"
     CDS             2820..3038
                     /locus_tag="ctg1_112"
                     /transl_table=11
                     /translation="MKQRITVTVDSDSYQFLKAYDVNISGLVSTTLQNEARRLRAERWQ
                     AENQEGMAEVARFIEMNGSFADENRDW"
     CDS             3040..3345
                     /locus_tag="ctg1_113"
                     /transl_table=11
                     /translation="MQFKVYTYKRESRYRLFVDVQSDIIDTPGRRMVIPLASARLLSDK
                     VSRELYPVVHVGDESWRMMTTDMASVPVSVIGEEVADLSHRENDIKNAINLMFWGI"
     CDS             3346..4155
                     /gene_functions="other (smcogs) SMCOG1077:phage integrase
                     family protein (Score: 94.8; E-value: 1.4e-28)"
                     /gene_kind="other"
                     /locus_tag="ctg1_114"
                     /transl_table=11
                     /translation="MSGSVIHSQSAAMVPAVYSAGQSAQLPVAIDYPAALALRQMSMVH
                     DELPKYLLAPEVSALLHYVPDLRRKMLLATLWNTGARINEALALTRGDFSLTPPYPFVQ
                     LATLKQRTEKAARRAGRMPAGQQTHRLVPLSDAWYVSQLQTMVATLKIPMERRNKRTGR
                     TEKARIWEVTDRTVRTWIGEAVAAAAADGVTFSVPVTPHTFRHSYAMHMLYAGIPLKVL
                     QSLMGHKSISSTEVYTKVFALDVAARHRVQFAMPESDAVTMLKNRHV"
     CDS             4293..4568
                     /locus_tag="ctg1_115"
                     /transl_table=11
                     /translation="MASVSISCPSCSATDGVVRNGKSTAGHQRYLCSHCRKTWQLQFTY
                     TASQPGTHQKIIDMAMNGVGCRATARIMGVGLNTIFRHLKNSGRSR"
     CDS             4613..4990
                     /locus_tag="ctg1_116"
                     /transl_table=11
                     /translation="MDEQWGYVGAKSRQRWLFYAYDRLRKTVVAHVFGERTMATLGRLM
                     SLLSPFDVVIWMTDGWPLYESRLKGKLHVISKRYTQRIERHNLNLRQHLARLGRKSLSF
                     SKSVELHDKVIGHYLNIKHYQ"
     CDS             complement(5001..5885)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Cloacin"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_117"
                     /sec_met_domain="Cloacin (E-value: 1.9e-90, bitscore:
                     295.4, seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDNEGSVPTEGIDYGDTMVVWPSTGRIPGGDVKPGGSSGLAPSM
                     PPGWGDYSPQGIALVQSVLFPGIIRRIILDKELEEGDWSGWSVSVHSPWGNEKVSAART
                     VLENGLRGGLPEPSRPAAVSFARLEPASGNEQKIIRLMVTQQLEQVTDIPASQLPAAGN
                     NVPVKYRLTDLMQNGTQYMAIIGGIPMTVPVVDAVPVPDRSRPGTNIKDVYSAPVSPNL
                     PDLVLSVGQMNTPVRSNPEIQEDGVISETGNYVEAGYTMSSNNHDVIVRFPEGSGVSPL
                     YISAVEILDSNSW"
     CDS             6113..6559
                     /gene_functions="other (smcogs) SMCOG1077:phage integrase
                     family protein (Score: 61.8; E-value: 1.7e-18)"
                     /gene_kind="other"
                     /locus_tag="ctg1_118"
                     /transl_table=11
                     /translation="MPAGQQTHRLVPLSDSWYVSQLQTIVATLKIPMERRNKRTGRTEK
                     ARIWEVTDRTVSTWIGEAVAAAAADGVTFSAPVTPHTFRHSYTMHMLYAGIPLKVLQSL
                     MGHKSISSTEVYTKVFALDVAARHRVQFSMPESDAVTMLKNRHA"
     CDS             complement(6696..6971)
                     /locus_tag="ctg1_119"
                     /transl_table=11
                     /translation="MVKKPSQQALNRAAVTVEQAEALAQRLADKPYGAPEKTEPEKQCR
                     TTISLGESMLVTIEDLALRNKRNGKDPKNVSAIVRVALEQYLKTLT"
     CDS             complement(6965..7609)
                     /gene_functions="other (smcogs) SMCOG1157:hypothetical
                     protein (Score: 48.9; E-value: 1e-14)"
                     /gene_kind="other"
                     /locus_tag="ctg1_120"
                     /transl_table=11
                     /translation="MITVVGGNKGGSGKTTIASNLAIALANKGREVCLLNGDLQRTAAK
                     HHAEREAAGLLPAITLVEKFDNLTQTLQALNEKFDDVIVDVAGRNSKEFITSGVVAHQI
                     IAPLQCSQPDLDTLTELEQQIDAMRNLNPELKVYCLQSMATTNPVLRGNERKEFLEYLE
                     EFPTIQVLDSVICFRKVYRDCMSNGTGVVETNNTAAKAEIEHLMNEVFGPW"
     CDS             7838..8809
                     /locus_tag="ctg1_121"
                     /transl_table=11
                     /translation="MNVYCDDGSTTIKLAWNDNGKISKSLSQNSFRHGWKVDGLGIRQT
                     FNYELDGKKYTYDEVSNQSILTTHIEYQYTDVNLLAVHHALLNSGLVPQPVSLTVTLPI
                     SEFYTKECQKNELNIQRKIENLMRPIRLNKGDVFTIEHVDVMPESLPAVFSRLVMDKVG
                     QFEKSLVVDIGGTTLDVGVIVGQFDSVSAIHGNSGIGVSSVTKAAMSALRMASSDTSFL
                     VADELIKRRNDPDFVRQVINDETKTDLVLNTIEGAIASLGEQVVNELGDFHHVNRVYVV
                     GGGAPLIYDSIKTAWHHLGQKVVMMESPQTALVEAIAAFKEE"
     CDS             8814..9206
                     /locus_tag="ctg1_122"
                     /transl_table=11
                     /translation="MDDERKRKKFTLYLHPEKAADFQTLEAIESVPRSERGELFRNAFI
                     SGMALHQLDPRLPVLLTAILSEEFSADQVVTLLSQTTGWKPSQADIRAVLTELGASQSA
                     EKMPPSATDSVQEAMNDVRLKMQKLF"
     CDS             complement(9211..10482)
                     /locus_tag="ctg1_123"
                     /transl_table=11
                     /translation="MFALADINSFYASCEKVFRPDLRNEPVIVLSNNDGCVIARSPEAK
                     ALGIRMGQPWFQVRQMRLEKKIHVFSSNYALYHSMSQRVMAVLESLSPAVEPYSIDEMF
                     IDLRGINHCISPEFFGHQLREQVKSWTGLTMGVGIAPTKTLAKSAQWATKQWPQFSGVV
                     ALTAENRNRILKLLGLQPVGEVWGVGRRLTEKLNALGINTALQLAQANTAFIRKNFSVI
                     LERTVRELNGESCISLEEAPPAKQQIVCSRSFGERITDKDAMHQAVVQYAERAAEKLRG
                     ERQYCRQVTTFVRTSPFAVKEPCYSNAAVEKLPLPTQDSRDIIAAACRALNHVWREGYR
                     YMKAGVMLADFTPSGIAQPGLFDEIQPRKNSEKLMKTLDELNQSGKGKVWFAGRGTAPE
                     WQMKREMLSPSYTTQWTEIPIASF"
ORIGIN
        1 gtgttctccg gggtaaaaag gtccgcacta ccgtcagccg gaaagccgtt gccgcaggcg
       61 accgcgtaaa ccgtcagttt gtggcagaac gtcctgacca gttgtgggtg gctgatttta
      121 cttacgtcag cacatggcag ggggtcgtct atgtggcgtt catcattgat gtgtttgccg
      181 gatacatcgt ggggtggcgg gtctcatcgt ctatggaaac gacattcgtg ctggatgctc
      241 tggagcaggc gttatgggcc cgtcgaccgt ccggcacagt ccatcacagt gataaaggtt
      301 ctcagtatgt atcgctggcc tacacacagc ggcttaagga agccggatta ctggcatcaa
      361 caggaagtac tggtgactcg tatgacaacg cgatggcgga gagcatcaat ggcctttaca
      421 aagcggaggt aatacaccgt aagagctgga aaaaccggac agaagtggag ctggccacac
      481 tcacgtgggt ggactggtat aacaatcgac gattgctgga aaggctgggc catatcccac
      541 cggcagaagc agaaaaagct tattatgctt ccatcggaaa cgatgatctg gcagcctgag
      601 ttcacagata aaacactctc caggaaaccc ggggcggttc aaacaccctt tcttcatcca
      661 tcctgcgcgc tccatctgat aatgttctga caggtaaaaa tcaaattctg tatgattttt
      721 gtgttatcga tttatgataa tatcagatat tttttcatta cttatgatta aaatcatatc
      781 taatatgaat ttatgtgtat tgcttaatta tcatatcacc tgcccgtttc ccgccgcgca
      841 gatccggttt ccggctgaag tggatccaga cctgatttgt tgctgagtat cggtaaaagt
      901 gcggcttata agctattctg aaacatggca agtgaatctg ggctgtataa ttccggcaag
      961 tgtcatctgt atttaaagga cgtgtgagta tgaaatttat ggaatgtgct gtccgggatg
     1021 tgatttatgg gaccaatgtc cgtcttgtca aaccggtcaa catttatgaa tgtgaactcg
     1081 gggacaatgt gtttgtcggc cccttcgttg agatacagaa aggctgtgtc attggtagtg
     1141 gaagtcggat acagtcgcac acgtttattt gtgagaacgt aacactgggg gagaagtgct
     1201 tcattggtca taacgtgacg ttcgccaacg atctgtttcg ttcaggagca ccagatccgt
     1261 caccggataa ctggatcagc attaccctgg gggattcggt tactgttggc agtggagcca
     1321 ttattctgtc tccgtatata tgcagcggag ctgttattgg tgcgggttca gttgtggtaa
     1381 aaccgattga gaacaaaggc atttatgcag gaaacccggc aagactgctc agaatattat
     1441 gaaaaagaaa agggccgtta ctggcccttt ttatcagagg taggtctgtg aatacggcag
     1501 gtgtacagaa atcgactgcc ggggatcgat ttccagggcc gcccggtatt ctgcgtcagt
     1561 gatatcacct tttttcggta aataaccgag agcatcgttt cccagccctg acagtatgcg
     1621 tattctggcg atccggaaat caaacaggct gtccatcata ccatgctccg gaaatgcggg
     1681 aggagtggcc agataggcag gtttgaccat tgtcctaaag tgccttcagg aagagataat
     1741 cgggaagcgc cttcactgat cgaaagttga ttttcaagaa ccgttctgac agcttcggct
     1801 ttgaactctt tagagtaacg ttgggttttt ctgctcatta ttagctcctt ctgatgccat
     1861 tctatttcag gaaggagtgt ccgttaaacc caggctacct catagttcat tttctgttga
     1921 tgcgctgaag atcatttcat tcaaaatact gacatctttc ataaagacct ccattttatg
     1981 tcggggaaaa ataaagcaca gataaaccat attttcacat ttaatttaca aattagtggt
     2041 atcagtcaca aataacttac aggtccggta atatcggtct gttagtgata tttactgaaa
     2101 atgatggaaa gatattgata acgtggttgc cataaccaat gcttcaggga agccgatatg
     2161 gttaatgtca ttacaatcgt cgccacagtt gcctgtgtat ccggatattt gaaatggatc
     2221 ttccagaagc ggactcgggt agtatcttca tggtttggct ttcagcagat ctgtgactct
     2281 gctatttatt gatgaatatg acctttacaa ttccagttat tgttctgatt gcaataatca
     2341 cttcatcaca ataatccacc attttttgtg attatctggc aataattttc ttttctgctc
     2401 cagagatccg aaaactcctg gttccggatc cgcggatcct tcgctgccgc ccgctggtcc
     2461 gctttcacag gatgtggtgt cccgctccgc tgacatgaca ctgtatgttg tgtttcttcc
     2521 cgtgttcccg agccagtcat cagcggcaga aaagatcgct tcgcttattc actgatcctg
     2581 attcacttcc ggaaaatcct gaatccgata aaaatcggat catagaaaaa cagtcatcct
     2641 gtaatttatc atggttacta cattgcaggt tattattgtc atgattactt ttcaggtcag
     2701 ttattgatgg tggtgttaat aatagctgga taacaatatt ccgttgccgg aggcatgtta
     2761 tagcgtaata ctggtgtata cttaatggtg tacagagagt atgtaagatg aggtgcatta
     2821 tgaagcagcg cattacagtc accgtcgaca gtgacagcta tcagtttctc aaggcatatg
     2881 atgtcaatat ctccgggctg gtaagcacca ccctgcagaa tgaagcccgt cgtctgcgtg
     2941 ccgaacgctg gcaggcagaa aatcaggaag ggatggctga ggtcgcccgg tttattgaaa
     3001 tgaacggctc ttttgccgac gagaacaggg actggtgaaa tgcagtttaa ggtttacacc
     3061 tataaaagag agagccgtta tcgtctgttt gtggatgtcc agagtgacat tattgacacg
     3121 cccgggcgac ggatggtgat ccccctggcc agtgcacgtc tgttgtcaga taaggtctcc
     3181 cgtgagcttt acccggtggt gcatgtcggg gatgaaagct ggcgcatgat gaccaccgat
     3241 atggccagtg tgccggtctc cgttatcggg gaggaagtgg ctgatctcag ccaccgagaa
     3301 aatgacatca aaaatgccat taacctgatg ttctggggaa tataaatgtc aggctccgtt
     3361 atacacagcc agtctgcagc catggtaccg gcagtgtatt ctgccggaca gtctgcacaa
     3421 cttcctgttg ccattgatta tccggcagct ctggcactcc gccagatgtc gatggttcat
     3481 gatgaactgc cgaaatatct gctggctccc gaggtgagtg ccctgcttca ttatgtcccg
     3541 gatctgcgcc gcaagatgct gctggccact ctgtggaaca ccggcgcgcg tattaatgaa
     3601 gcactagcgc tgacgcgggg ggatttttcg ctcacgcctc cgtatccgtt tgtgcagctg
     3661 gccactctga agcagcggac agaaaaagcc gccaggaggg caggaaggat gcccgccggt
     3721 cagcagactc accgtctggt tccgctctcc gacgcctggt acgtcagcca gctgcagacg
     3781 atggtggcca cactgaaaat ccccatggaa cggcgtaata aacgaacagg caggacagag
     3841 aaagcgcgga tctgggaagt gacggacaga acggtcagga cctggattgg ggaggcggtt
     3901 gccgccgctg ctgctgacgg tgtgacgttc tctgttccgg tcacaccaca tacgttccgc
     3961 cattcctatg cgatgcacat gctgtatgcc ggtataccgc tgaaagttct gcaaagcctg
     4021 atgggacata agtccatcag ttcaacggaa gtctacacga aggtttttgc gctggatgtg
     4081 gctgcccggc accgggtgca gtttgcgatg cctgagtccg atgcggtcac aatgctgaaa
     4141 aacagacatg tataataagt cacaattatg aattgtgatt tcttctataa aaaagagacc
     4201 actgcaatat gtgatctctt gtattatttc ataattgggt gatgctgcca acttactgat
     4261 ttagtgtatg atggtgtttt tgaggtgctc cagtggcttc tgtttctatc agctgtccct
     4321 cctgttcagc tactgacggg gtggtgcgta acggcaaaag caccgccgga catcagcgct
     4381 atctctgctc tcactgccgt aaaacatggc aactgcagtt cacttacacc gcttctcaac
     4441 ccggtacgca ccagaaaatc attgatatgg ccatgaatgg cgttggatgc cgggcaaccg
     4501 cccgcattat gggcgttggc ctcaacacga ttttccgcca tttaaaaaac tcaggccgca
     4561 gtcggtaacc tcgcgcatac agccgggcag tgacgtcatc gtctgtgcgg aaatggacga
     4621 acagtggggc tatgtcgggg ctaaatcgcg ccagcgctgg ctgttttacg cgtatgacag
     4681 gctccggaag acggttgttg cgcacgtatt cggtgaacgc acgatggcga cgctggggcg
     4741 tcttatgagc ctgctgtcac cctttgacgt ggtgatatgg atgacggatg gctggccgct
     4801 gtatgaatcc cgcctgaagg gaaagctgca cgtaatcagc aagcgatata cgcagcgaat
     4861 tgagcggcat aacctgaatc tgaggcagca cctggcacgg ctgggacgga agtcgctgtc
     4921 gttctcaaaa tcggtggagc tgcatgacaa agtcatcggg cattatctga acataaaaca
     4981 ctatcaataa gttggagtca ttaccaacta ttactgtcca gaatctccac ggctgaaata
     5041 tatagcggag aaactccact gccttcagga aaacggacaa tgacatcatg attattactg
     5101 gacatcgtat aaccagcctc aacataattc cctgtctcag aaataacgcc atcttcctgg
     5161 atttcgggat tagaccgaac tggagtattc atctgaccca cacttaatac caggtccggt
     5221 agatttggtg atacaggggc actgtaaaca tctttaatat tggttcccgg acgactccgg
     5281 tccggaactg gaacggcatc cactactggc actgtcatcg gaatacctcc gataatagcc
     5341 atatattgtg taccattctg cataaggtcc gtcagacgat attttaccgg tacattatta
     5401 cccgctgctg gtaactggct ggcagggata tccgttacct gctccagttg ctgtgtaacc
     5461 ataagacgaa taattttttg ctcatttccg gaagcaggct ccagacgggc aaaagaaaca
     5521 gcagccgggc gagacggttc tggcaaacca ccacgtaaac cattttcaag aactgttcgt
     5581 gcagcggaaa ctttctcgtt tccccagggg ctatgcacac tgacagacca tcccgaccag
     5641 tctccctctt caagttcctt atcaagaata atccggcgaa taattccagg aaaaagaaca
     5701 ctttgtacaa gtgcgatacc ttgtgggctg taatcccccc atcccggagg catggatgga
     5761 gcgagacctg atgagcctcc gggtttcaca tcaccgcccg gaattcgtcc tgttgacggc
     5821 cacacaacca ttgtgtcccc gtaatcaata ccttctgtcg gtacactacc ttcattatca
     5881 ctcatagaaa acctctttga ctttaaaaac aatcaattaa aattaaatac tgtacatata
     5941 accactggtt ttatgtacag atcaaaaatt acgccgctgt gttttctctg tcaagactgt
     6001 ggatttcaat ttttgtgaaa acgatcaaaa aacaggcact cacaccacgt gctattctcg
     6061 cctgatacca caaaaaactg cacaagcatt actggtcagg acggcaggaa gaatgcccgc
     6121 cggccagcag actcaccggc tggttccgct ctcggactcc tggtacgtca gccagctgca
     6181 gacgatagtg gccacactga aaatccccat ggaacggcgt aataaacgaa caggcaggac
     6241 agagaaagcg cggatctggg aagtgacgga cagaacggtc agtacctgga ttggggaagc
     6301 ggttgccgcc gctgccgctg atggtgtgac gttctctgcc ccggtcacgc cacatacgtt
     6361 ccgccattcc tatacgatgc acatgctgta tgccggtata ccgctgaagg tcctgcagag
     6421 cctgatgggg cataagtcca tcagctcaac ggaagtctac acgaaggtgt ttgcgctgga
     6481 tgtggctgcc cggcaccggg tgcagttttc gatgcctgag tccgatgcgg tcacaatgct
     6541 gaaaaacaga cacgcataat tcataaatca taattatgaa ttgtgattta ttctgtaaaa
     6601 aagagaccac tgcaatatgt gatctcttgt atgcaagggg gcttaaacag tatgaattca
     6661 caagtgtgat ttcataagta ataacttttt gattattatg ttagtgtttt taagtattgc
     6721 tcaagggcta ctctgacgat ggcacttaca ttttttggat ctttaccatt gcgtttattc
     6781 ctcaatgcca gatcttctat tgtgacaagc atgctttcac caagagagat tgtcgtccga
     6841 cattgttttt ctggttcggt tttttccggc gcgccgtatg gtttatccgc aaggcgctga
     6901 gccagagcct ctgcttgttc taccgtaact gcagctctgt ttaatgcttg ctggctgggt
     6961 ttcttcacca tgggccaaat acctcattca ttaaatgttc aatttctgct ttggctgctg
     7021 tattgttcgt ttctactaca ccggtgccgt tgctcatgca atcgcgatag acttttctga
     7081 aacaaataac tgaatccaga acttgaattg ttgggaattc ttcaagatat tcaaggaatt
     7141 cttttctctc atttcccctc aaaaccggat tggttgttgc catactttgt aaacaataaa
     7201 ccttaagttc cgggttaagg ttacgcattg cgtctatctg ttgttctagt tctgtaagag
     7261 tatccagatc tggttgagaa cactgtagtg gcgcaattat ttgatgtgcg acaactccac
     7321 tcgttatgaa ttcctttgag tttcttcctg cgacatccac tattacatca tcgaactttt
     7381 cattcagagc ctgtagtgtt tgtgtcagat tatcaaattt ctcaacaaga gttattgctg
     7441 gtaaaagtcc tgcagcttct cgttccgcat gatgttttgc ggctgttcgt tgtagatctc
     7501 cgtttaacag gcagacttcc cttcctttat ttgcgagagc aatagccagg tttgatgcaa
     7561 tggtagtttt ccctgaacca cctttgttcc caccaactac agtaatcatt gcaacctcat
     7621 aaatgtgatg tgtgaagtat gatgatattt tgacacggta acctgaggtg tcaatatgcg
     7681 ttcatattta tgaagtatga aacatgaagt gtttcatatg atgtaataaa taatacttgt
     7741 gttttgtgat ttcataacta tgatagtact caaattgagt attaccttgc aaccagaaac
     7801 agtgatttac tcagattgag tatttaaggg gctatagatg aacgtatact gcgatgatgg
     7861 ttcaacaaca atcaagttgg catggaatga caatgggaaa atcagtaagt cgttgtcgca
     7921 aaactcattt cgtcatggat ggaaggttga cgggttaggg attcgccaga catttaacta
     7981 tgaactggat ggtaaaaaat acacgtatga tgaagttagc aaccaatcta ttcttacgac
     8041 tcatattgag tatcaatata cggatgttaa cctgttagct gtgcatcacg ctttactgaa
     8101 tagtggatta gtgcctcagc ctgtatcatt gactgtgact ttgcctatca gtgagttcta
     8161 cacgaaagag tgtcaaaaaa atgaactcaa cattcagcgt aaaattgaga atttaatgag
     8221 gccgattcgt cttaataaag gcgatgtttt caccattgaa cacgttgatg tgatgcctga
     8281 atcattgcca gctgtgtttt ctcgtctggt catggataaa gttggtcagt tcgaaaaatc
     8341 gctggtagtt gatattggcg gcactacgct tgatgttggt gttatcgttg gtcaatttga
     8401 ctctgtaagt gccattcatg gtaattctgg cattggtgtg tcttcagtta cgaaagctgc
     8461 aatgagtgca ttgcgcatgg catccagtga taccagtttc ctcgttgcag atgaattgat
     8521 taaacgtcgt aatgacccgg actttgttcg gcaggttata aatgacgaaa caaaaactga
     8581 tctggtcctt aataccattg agggggctat tgccagtctg ggggagcaag tagtcaatga
     8641 gctcggtgat tttcatcatg tgaatcgtgt ttatgttgtc ggtggtgggg caccgttgat
     8701 ctatgattcg ataaaaacgg catggcacca tcttgggcaa aaagtagtga tgatggagtc
     8761 gccacagaca gcactggttg aagctatcgc ggctttcaaa gaggagtaat attgtggacg
     8821 atgaacggaa aaggaaaaaa ttcacacttt atctgcatcc ggaaaaagct gcagactttc
     8881 aaactttgga agcgatagag tccgttccgc gttctgagcg tggtgagctg ttccggaatg
     8941 catttatttc tggaatggcg ttacaccaac ttgatcctcg cctgcctgta ttgctgactg
     9001 ccattttgag cgaggagttt tcagcagatc aggttgtaac cttactcagt cagacgactg
     9061 gatggaagcc ttctcaggcc gatatcagag ctgtgttgac tgaactcggt gcttcgcaat
     9121 ctgctgaaaa aatgcctcct tctgctactg attcggtgca ggaggcaatg aatgatgtgc
     9181 gccttaaaat gcaaaaatta ttctgatata tcagaatgaa gcaatgggga tctcagtcca
     9241 ttgtgttgta tacgaaggcg agagcatttc ccgtttcatt tgccattcag gggcggttcc
     9301 tcgccccgca aaccacactt tcccttttcc cgactggttc agttcatcga gtgttttcat
     9361 taacttttca ctgtttttac ggggctggat ttcatcaaat aatcccggct gcgctatacc
     9421 cgatggtgtg aaatcagcca gcatgactcc tgccttcata tagcggtacc cttcacgcca
     9481 gacatggttt aaggctctgc atgcggcggc aataatgtcc cggctgtcct gtgtgggcaa
     9541 tggaagcttt tccacagcgg cattgctgta acagggttct tttactgcaa agggggatgt
     9601 ccgtacaaat gtcgtcacct gccggcaata ctgacgctcc ccacgtagtt tctctgcggc
     9661 ccgctctgca tactgaacaa cagcctggtg catggcatct ttgtctgtga ttcgttcacc
     9721 aaaactgcga ctacagacaa tctgctgttt tgccggtggt gcttcttcca gggatatgca
     9781 ggactcgccg ttgagttcgc gtaccgtacg ctcaagaatg acgctgaagt ttttccggat
     9841 gaatgccgtg ttagcctgcg ccagctgcag tgctgtgtta atacccagcg cattcagctt
     9901 ttccgtcagt ctgcgtccta ctccccagac ctcaccaact ggctgcagtc ccagtagctt
     9961 caagatccga ttacggtttt ctgccgtcag cgcgaccaca ccggaaaact gtggccattg
    10021 ctttgttgcc cactgtgcac ttttagccag cgtttttgta ggcgcaatgc ccacccccat
    10081 ggtgagtcct gtccagctct ttacctgttc cctgagctga tgaccaaaaa actccggaga
    10141 gatgcaatga tttatccccc gcaaatcaat aaacatttca tcaattgagt agggctcaac
    10201 tgcgggagaa agcgactcca gaacagccat gacccgttgg ctcatgctgt ggtacagcgc
    10261 ataattgctg gaaaatacat gtattttctt ctccaggcgc atctgtctca cctgaaacca
    10321 gggctgcccc attctgatgc caagggcttt tgcctccggg ctgcgcgcga tcacacagcc
    10381 atcgttattg ctgagtacga tgaccggttc gttgcgaagg tccgggcgga aaactttttc
    10441 acatgaggcg tagaaactgt tgatatcagc cagtgcaaac atcagcgtaa ctcccgcgtc
    10501 ctgtgtatca cgtgagtgac aacaccaaaa atacagatgt tttccggata cagtgtgcgg
    10561 aactccgggc tgtctgaaac cggctccagt gccgggcgtg ggcgcaacag cagtcgtttg
    10621 acggtgaact caccgtcgat ctcagcgata acgatgtccc cgtgttgtgg tttttcggcc
    10681 ctgtccacta ccagcagatc accattctgc acgccagcct ggttcatcga ttcaccgctg
    10741 gcgcgcagaa agaaggtggc tgcaggtctg ctgatgcaat agctgttcag atccagttcc
    10801 tgctcagcat aatcagtggc aggcgaagga aaaccggcct ggcaacgatc ggcaaacaac
    10861 ggtcgcacgt aactgtcatc gcctg
//
