LOCUS       NZ_CP032088.1          20666 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP032088.1 Escherichia coli strain ATCC 25922 plasmid pL25922_2,
            complete sequence.
ACCESSION   NZ_CP032088
VERSION     NZ_CP032088.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-06-07 14:12:20
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 7897
            Orig. end    :: 28563
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..20666
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:11053]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11053
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..20666
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..20666
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             189..1166
                     /locus_tag="ctg1_10"
                     /transl_table=11
                     /translation="MRYLTELICQLYRLTDHHKLTAATFKNLADIKLVEPTADADTILQ
                     LENIFSEYSLRYIDRDLAEILSNIITTDKNHSLDFDFNKIQSLTASKSFGCGWNKVING
                     SWFKNLYSWGEGMYPAKNLKAENISDWEDNIWHIEHEGFNPRDPINVKYYSWLDRYVAL
                     NSGGSHHAAMVVYQSVRDKLEYKREAVIEQLSINSNTVEILGQNYYSFIFQIKHPSNKT
                     ENYTSEYEFTDALKDFGQNRHTTLKPVNYVSNIKLAFIPKDALKTNSETFRNWFYSAIS
                     YGKIISLPDYLKNPAHYHTYHYSHELDSITLGNPSRKYKLRGDS"
     CDS             complement(1163..1519)
                     /locus_tag="ctg1_11"
                     /transl_table=11
                     /translation="MKYQVREFITDKYAKAVNILKDNLKENYHVFYGVRLSEILFPASE
                     YGTDAFFKEFELINSVILPLVIFDLTQRKPMMIISFDKIPDASLLEGTNIVVLECTTLA
                     DLLTNDNIGFLYKS"
     CDS             complement(1659..2102)
                     /locus_tag="ctg1_12"
                     /transl_table=11
                     /translation="MAKIYQFPQGDERGKFREEIARERKKRFAVKTGSTFVKWLGWTWF
                     YLRLLVASVLHFISVFVLAILGAFKWAVFWLGGILCVITWYHLDHQLWTPQNLTIPVIT
                     ATWIFGLLAEPLMELLNKTMPWHKLLVPEPAGESTENSSETSQ"
     CDS             complement(2106..2948)
                     /locus_tag="ctg1_13"
                     /transl_table=11
                     /translation="MEQIKLHKQGGAAVIIIPASMIENTGWEDGTLLDVLEINEALHIR
                     RKTGSGALATKSCPSLFSSTMRHVNYDKIIRYNSGLNLLVNELSFSARRVFFICLYYYF
                     ENKLESDKSLLIRADKYAEFVGVDRSVAYKQMKDAADFFSRNKKLITHCDYISNEGLLR
                     VMFSSKTINYITAIDARKYQVTELPLKSALSLQGRYSWPLYQLIKFSHLKSFTIGVDEL
                     KKEIGYIQNQKFSFFKRDGINIAIDEITERTDVKNIKCVNAERQGRRVSKVRFEIEMR"
     CDS             complement(2969..3454)
                     /locus_tag="ctg1_14"
                     /transl_table=11
                     /translation="MNLTAFCDYVESEGYIDIAFSHVIEPYITMLKDSYTTQVLISSVR
                     LADQNSNMLYQFIRKQYSSGKKTFFDIEVDVLKDELELFRIDNGEKVYLYQNFKDFNKV
                     FLQKNIEKINQYTEINHLEVKIIERVARRASKLRFSYKIDKESEGLDTRIPYGFRGA"
     CDS             complement(3451..3807)
                     /locus_tag="ctg1_15"
                     /transl_table=11
                     /translation="MNLLSVTKKTKIRHRNEINSTFSSLPLSARRILFMAMAQIDSREE
                     LSEGATFRITAREYAFIADIDVTGAYRQLKEGQKNFRLVLFAFLEINFSQLRAIKALDI
                     RRREVNYLLMQSGL"
     CDS             5029..5280
                     /locus_tag="ctg1_16"
                     /transl_table=11
                     /translation="MSYQILTTTAASITDLKKNPMGTVAEGEGDAVAILNRNEPAFYCV
                     PPKLYAYYRELAEDAELNAVADERMKNPEIVKVNLDDL"
     CDS             5270..5551
                     /locus_tag="ctg1_17"
                     /transl_table=11
                     /translation="MTYELAFDRRALKEWQKLGHTIREQFKKKLAERLENPRVPAARLH
                     GHADRYKIKLRASGYRLVYQVIDEKVVLLVIAVGRRESSEVYQIADLR"
     CDS             5697..6020
                     /locus_tag="ctg1_18"
                     /transl_table=11
                     /translation="MQNYAKSVATEILRQLGGNRFIVMTGAKSFSYFDENGECGLTFRL
                     PSNFAMKGINLVKIKLDFTDTYQVKFSRVRGAEVKDISRFDNIYCDQLARLFTQETGLH
                     TVL"
     CDS             6065..6310
                     /locus_tag="ctg1_19"
                     /transl_table=11
                     /translation="MDKDKIIKKNRGNYSYVIRTMDEDGDTVFHVLKYVKTIDKTKSRK
                     TVRKLIMDEKLNLASLMLLDNWVLCDCLTKGDENAE"
     CDS             6300..6515
                     /locus_tag="ctg1_20"
                     /transl_table=11
                     /translation="MQNKPTPEEVKNARVAAGLTLKEAADIFGYQLNSWQMKESAGKAS
                     RSLSIGEYQYLLLLANMHPSYRLVKK"
     CDS             6608..6937
                     /locus_tag="ctg1_21"
                     /transl_table=11
                     /translation="MKVLTFKNDTVSVGDIFVSSWGYEQTNVTFYQVLSVHGKKTVTVR
                     EIRANSEYTDSMVGFKTPVLNDFTGECFKRQIKDFGDELAIKIEDFETAYKTLPEEKHR
                     FSSYY"
     CDS             6979..7158
                     /locus_tag="ctg1_22"
                     /transl_table=11
                     /translation="MEREFSAKASLNRNIKFWFEQCGLSKERVIHCIDNWYDLAYPPSE
                     QEKVRTGESKKRSN"
     CDS             7196..7393
                     /locus_tag="ctg1_23"
                     /transl_table=11
                     /translation="MGQPDTVTPDSIARNKMSERILSAINDVEKGGRPVFPLMPFHVFP
                     EYMALLRKALEKKTQKRTDK"
     CDS             7406..7678
                     /locus_tag="ctg1_24"
                     /transl_table=11
                     /translation="MTKHDFVSFVSGELRQGAVRFSLAFNSKGEIVLHWTNKAGIRVWR
                     ILSGNRGKKPSKANLERMSNFRRWLFDARQGMEGYTQQPEQSNLS"
     CDS             complement(7544..7879)
                     /locus_tag="ctg1_25"
                     /transl_table=11
                     /translation="MLEHQQKCKKADVVMAEHTYVCDRKPDQCGKDSAVRFATRTVWQE
                     AQAQSRAIYQKAPPEIREGFGYSAKVALFRLLSVAFHALTGIKKPAPEVTHSFKVSFAW
                     FFATITT"
     CDS             7885..8262
                     /locus_tag="ctg1_26"
                     /transl_table=11
                     /translation="MSGARFTAMQEKLNVVIEERREDAEREAAERAERERKRQELLQLI
                     AGEGFSPEELLGITEDAPKTRKKTLPKAPPKYQFEENGETKYWSGRGRAPKPIAEALAG
                     GRSLDEFIIKKDASSSAGDEH"
     CDS             8317..8724
                     /locus_tag="ctg1_27"
                     /transl_table=11
                     /translation="MSLTLPLMYFQTGADLSKITHHEVHYQDGFVQQAWLQPEIQLFVV
                     CIARKKGSRREIKGGMAVLTSIPASNGAELAKALDNVMRQSDELRPLAGKDENVFIPAR
                     IGISGEEPPTEQELLSVFYQQCLKHGSWGSA"
     CDS             8981..9445
                     /locus_tag="ctg1_28"
                     /transl_table=11
                     /translation="MNMTARNAGLSFRSPDDDDSHRTRYSELQQAFDFYNQRLFDGELP
                     ECLITFQRVTQDLFQGKFALSWFDRFSVQVEQQKEMAAVIEQWRETIAQAHQNAEPGLI
                     LKRCCQCHRRTGAMITICLLRLLRTSQKGTKSNISVGVWCCCLGEVRTEY"
     CDS             10001..11053
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Pantocin_Microcin_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ThiF"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_29"
                     /sec_met_domain="Pantocin_Microcin_RRE (E-value: 8.1e-21,
                     bitscore: 65.6, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="ThiF (E-value: 1e-47, bitscore: 154.0,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYILGRYVKIARYGSGGLVGGGGKEQYVENLALWENIIKTAYCF
                     ITPSSYTAALETANIPEKDFSNCFRFLKENFFIIPGEYNNSTENNRYSRNFLHYQSYGA
                     NPVLVQDKLKNAKVVILGCGGIGNHVSVILATSGIGEIILIDNDQIENTNLTRQVLFSE
                     DDVGKNKTEVIKRELLKRNSEISVSEIALNINDYTDLHKVPEADIWVVSADHPFNLINW
                     VNKYCVRANQPYINAGYVNDIAVFGPLYVPGKTGCYECQKVVADLYGSEKENIDHKIKL
                     INSRFKPATFAPVNNVAAALCAADVIKFIGKYSEPLSLNKRIGIWSDEIKIHSQNMGRS
                     PVCSVCGNRM"
     CDS             11050..12264
                     /locus_tag="ctg1_30"
                     /transl_table=11
                     /translation="MNTANILSVNYGAYNAIRMLIGVYHAAFLISTGVTISQLAVLQIV
                     FSVTVLILDFPLSVIADRFYRKQVVVSGVFFTILFYPLCIQSPDMLALVFSEIFYAIGI
                     CCISGAIEGWVLSALDGRNEKFTLCAHLCERVSSFGSVITGAVGILVVYFYDSYKSGYI
                     VSFFLMFVVFIVFLCVKTNGSGGEKEARDSIIKQAKESIGLITGSYNGTYFLSITCMFT
                     IGIQVIYHFWQPIMLSGESIGSLSKRELITLLMCHIGAFSMQYIANYLMPKIDVRCKLY
                     ILVCTLCSFLSSIACILLFMLITDNKVVLGVAIFSIIHGMISTIPVGAQNIFISRLNGN
                     YKNIISGALGLVSLSCRVASISVLGVISVLPGNMPVTTYIFISAIACVLCGCLFLMWSF
                     KKEMV"
     CDS             12261..13064
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 60.7; E-value:
                     2.4e-18)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_31"
                     /transl_table=11
                     /translation="MTIKHAEELTEEVILNMNYPDFVALMQQDNTPPGAEYTIDYWIKH
                     GCINKKSHLLDLACSTGFSSRECFKKEGASAEGIDISESAVMVANEKAKKLKANNLLKY
                     YVADACDLPFEDNSFTHVLGGCNFAFIQNRLIALNETHRCLNHMGSMCISNFYYRRKIS
                     DKLINDVYNAINFRPNPLWTLEYWHQFFSERFTLVSEENHEMESQSEDELKADIYDYIF
                     NRNEFTKGLNGSLQNVFFERFLKIRRPLNIQRDYQGVTLQIWRKK"
     CDS             13049..14818
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_Arg_deC_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1264:diaminopimelate decarboxylase (Score: 134.4;
                     E-value: 5.8e-41)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_32"
                     /sec_met_domain="Orn_Arg_deC_N (E-value: 3.7e-21, bitscore:
                     67.0, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQKITPSKIVKHARELIIKGIESGENSFVIFDVDGALERLDHYR
                     CQLKSFFPNSSIAYSYKSNNLAQWCQIISGKGLYAEVCSVDEMNLAKRDGFKRIVFDGP
                     LKKTSELLKAIEIGALIEVDNIDECKRLNELCKLHKLTCRIHLRLSHYYDDNLSRFGLS
                     ESEAINLLEMLISKSEYLILDGFHLHVGSNLPNAEKICKAIIQYHELILRYMPDDGTLN
                     LGSGIPADSFSASSDNPTPCPEVFFSSIYDTIKNCFGTVCDKWNYIFEPGRHLVEDFGY
                     FIGKVISTKNRYGVKVAQTNIGINWIPSIRNWDHSFTLFHNHNHISDDKSDEYIIAGFN
                     CFECDCLFPSVILPSNLSDYLFSVRGCGAYDMQTGNQWTRNLYAVYTITNDVVNISRIH
                     RRELDFRKYDVSLTPSGIKVNDEITLLYPALKYAEELYLLINQNKINFIKSMAWPAFVN
                     NISDSVSFIEQSMIDNQNEKALILFIKYKTKIAGVVSFNIIDHANKTAYIGYWLGANFQ
                     GKGIVTNAINKLIQEYGDSGVIKRFVIKCIVDNKKSNATALRCGFTLEGVLQKAEILNG
                     VSYDQNIYSKVIG"
     CDS             complement(14875..15219)
                     /locus_tag="ctg1_33"
                     /transl_table=11
                     /translation="MPEILNGDILFIEDSRKSIATIERLFSMLKLNRVFDKVSAIILGK
                     HELFDCAGSKRRPYEVLTEVLDGKQIPVLDGFDCSHTHPMLTLPLGVKLAIDFDNKNIS
                     ITEQYLSTEK"
     CDS             complement(15267..15908)
                     /locus_tag="ctg1_34"
                     /transl_table=11
                     /translation="MMIQSHPLLAAPLAVGDTIGFFSSSAPATVTAKNRFFRGVEFLQR
                     KGFKLVSGKLTGKTDFYRSGTIKERAQEFNELVYNPDITCIMSTIGGDNSNSLLPFLDY
                     DAIIANPKIIIGYSDTTALLAGIYAKTGLITFYGPALIPSFGEHPPLVDITYESFIKIL
                     TRKQSGIYTYTLPEKWSDESINWNENKILRPKKLYKNNCAFYGSGKVEGV"
     CDS             16834..17013
                     /locus_tag="ctg1_35"
                     /transl_table=11
                     /translation="MDFMSILGRCLLLPFPVAMFVGCLFLGIDDRFTGMFMSFIVGCLS
                     WYITKPKPQKAEVA"
     CDS             complement(17415..17687)
                     /locus_tag="ctg1_36"
                     /transl_table=11
                     /translation="METHPSWFIGGKSVDADDVIEPFKVQDNKKTNLLNFFLERCRVQP
                     ICGWISRWEKVFNVIDSALRDKSESITNKKRTEDTSGNTSDHQAA"
     CDS             complement(17741..17956)
                     /locus_tag="ctg1_37"
                     /transl_table=11
                     /translation="MAFLRSAKVDEFGGVSQLGGFLKGCYEFISKDVPVISVFDGDEAG
                     SKKEPDYKATLVKNKLDLSQIKTIFL"
     CDS             complement(18003..18671)
                     /locus_tag="ctg1_38"
                     /transl_table=11
                     /translation="MYIPSSKSIDDIYHNLLVPYVRSEVASAMKTSVQVIHDKLLEVSE
                     KITNEMILSGIDDCSFMIKAPPSLDELFGRFEVSIKDTIENVISSKGMGLQCLSLFSSF
                     KSISERKLTLGKKTIWMVEEPESFLHPSLGRSCNHIFKSLMDVAYVLITTHSLSFVSDE
                     PSKIIELYKDDAGVTKDKKHEKRFNAVASIRENLGVRFSDFFNISSSAVSLKVSPTNNI
                     "
     CDS             complement(18682..19314)
                     /locus_tag="ctg1_39"
                     /transl_table=11
                     /translation="MEIVSFKVSQYRSISGEISSDNFNGLTIVGQNNSGKTNLLKAMRV
                     FFEGKFNPDLYDYEKDKPHGVKQGQTSFAVRFTFSESELDDVSEDLSQDDDDDDDDSII
                     ELGVLGGQEEPSNSISFDDGSSKQQESKPTQSRGRKLSLRDRYLQLFNMIDDSRLSSPQ
                     NEVTVHLTISNKNNYFYTVFKGYKRKPEVTSSMYTSVERRFIEKNTF"
     CDS             complement(19420..19929)
                     /locus_tag="ctg1_40"
                     /transl_table=11
                     /translation="MATEWVDVADNAVKIGLGALITIVGGWITLKLTHCHEIRKDAIAQ
                     RLRDIDKKTDRYIDFLSSSQTLMQKYLYESCNPGSEDYTNYMRLHNIVSLTSSPELRIY
                     AFDTQSKVSQFILLRKPNEPEVIDSCRNAARNAVSVLQGAVSAELLQDKAALQDKQHAW
                     WAFWRK"
     CDS             complement(20021..20263)
                     /locus_tag="ctg1_41"
                     /transl_table=11
                     /translation="MDKSPVVATLKLVDEDHKHNPIVFDVVNDSTGTLPKQITLAKNLP
                     KFEENYKYLQSYCANSTEKMYEKMMPEIRNLNKGL"
     CDS             complement(20242..20439)
                     /locus_tag="ctg1_42"
                     /transl_table=11
                     /translation="MTIQLFVDKDGSIDGEFISEGLCDAMPLTWNITFNSDSPSLINFI
                     FARKFQIRQLVNGQWIKALL"
     CDS             complement(20457..20630)
                     /locus_tag="ctg1_43"
                     /transl_table=11
                     /translation="MSGRITTLCTAFGVVIAAVGLYLPYKNELNAALYQREFLTGKWST
                     DADILLIVGILD"
ORIGIN
        1 tgatgaactt cagactttca gcccattttg aggacatact ggaagctgaa gctatcagaa
       61 cagggcagag caaaacaacc gttctcaaag cagcgctggc gatgtacaac agccaggatg
      121 aaaacataaa gaatcactgg ttactggaat cggcaaaatt ctaaccatag aagtatggat
      181 gattatctat gagatattta accgaattaa tctgtcaact ctacaggttg acagatcacc
      241 ataaactgac cgctgcaacg tttaaaaatc ttgctgatat taagttagtt gaacctacag
      301 cggatgcaga caccatattg cagcttgaaa atatatttag cgaatactca ctaagatata
      361 ttgacaggga tctggctgaa attctgagta acataataac tacagataaa aaccactctc
      421 tggattttga ttttaacaag atacagtctc tgactgcctc gaaaagtttc ggttgtggat
      481 ggaacaaagt aataaatggt agttggttca aaaaccttta ttcatggggg gaagggatgt
      541 atcccgccaa aaacctgaaa gctgaaaaca tttcagactg ggaggataat atatggcaca
      601 ttgagcatga aggtttcaac cctcgcgatc ctattaatgt taaatattac tcttggcttg
      661 accgatatgt agctttaaac agtggtggtt cacatcatgc agcaatggtt gtatatcaat
      721 ctgtcagaga caaattagag tataaaagag aagcggttat tgaacaactg agcataaatt
      781 caaacaccgt tgaaatactt ggccagaact actattcatt catattccag ataaaacacc
      841 ctagtaataa gacagaaaat tatacatcag aatatgaatt tacagatgct ttaaaagact
      901 ttggacaaaa taggcatacc acacttaaac ctgttaatta cgtttctaac ataaaattag
      961 catttattcc caaagatgct ttaaaaacaa acagcgagac attccgcaac tggttttatt
     1021 ctgcaattag ctacgggaaa ataatatcac tccctgatta tctgaaaaat ccagcacatt
     1081 atcatacata tcattactca catgaactag actcgataac acttggcaac ccaagcagaa
     1141 aatataaact gagaggagat tcttagcttt tatataaaaa accaatgtta tcatttgtca
     1201 gaagatcggc gagggtagta cattcaagaa ccacaatatt tgttccttcc aacaaactgg
     1261 catcaggtat cttatcgaag ctgataatca tcattggctt gcgttgtgtt aaatcaaaga
     1321 ttactaatgg aagtattaca ctgttaatta attcaaactc tttaaagaaa gcatcagtgc
     1381 catactcact ggctggaaaa agaatctcac ttaatctcac accataaaaa acatggtagt
     1441 tttctttaag gttatccttt aaaatattaa cagccttcgc atatttatca gtaataaatt
     1501 ctctcacctg atatttcata aaattctccg acaagaaccg actgtaggtc accgggcaaa
     1561 cgttgcggaa tggcgtcaga gacgtcattt tgcggtgttt gccctatcct gcatcgcagt
     1621 gaaaaggcag gggctggcat aacgactaag tagcgtcatt actggctcgt ctcgctgctg
     1681 ttctctgtgc tttcgcccgc aggttcggga accagtaact tgtgccaggg catggttttg
     1741 ttgagcagct ccatcagcgg ttcagccaac agaccaaaaa tccaggttgc cgtaatcacc
     1801 ggtatagtca gattttgtgg cgtccataac tggtgatcga gatgatacca ggttatgaca
     1861 cacagaatgc cacccagcca gaacacagcc catttaaacg cgccaagaat ggctaacaca
     1921 aaaacagaga taaaatgtaa aacactggcg accagaagac gaagataaaa ccaggtccat
     1981 ccaagccact taacaaaagt gctccctgtt ttcaccgcaa aacgtttctt acgttctctg
     2041 gcgatttctt ccctgaattt accgcgttcg tccccttggg ggaattgata gattttagcc
     2101 atgagttacc tcatttcgat ctcaaaacgg actttgctga ctcttctacc ctgcctttca
     2161 gcattaacac atttaatgtt tttaacatct gtcctttctg ttatttcatc aatagctata
     2221 ttgattccat ctcttttaaa gaaagaaaac ttttgatttt gaatataacc tatttctttc
     2281 ttaagttcat ctacacctat agtgaaagat ttaagatggc taaattttat cagttgatat
     2341 aaaggccatg agtatcttcc ttgaagagac aaagcagatt ttagaggaag ctcggtaacc
     2401 tgatatttac gggcgtctat cgctgtaata taatttatcg tcttagacga aaacataaca
     2461 cgaagcaatc cctcattcga aatatagtca caatgtgtaa ttaatttttt atttcttgaa
     2521 aagaaatctg ctgcatcctt catttgctta tatgcgacag aacgatcaac accaacaaat
     2581 tctgcatact tatcagcccg gatcaatagc gacttatccg attcaagttt attttcaaag
     2641 taataatata aacaaataaa aaagaccctt cttgccgaaa atgacagttc attaactaac
     2701 agatttaatc cgctattata tctaatgatt ttatcgtagt taacatgcct catagtagat
     2761 gaaaaaagag aaggacaaga tttagtagct aaagctcctg atcctgtctt tcttcttata
     2821 tgaagagcct catttatttc tagtacatcc aataaggttc catcttccca tccggtattt
     2881 tctatcatac tggcaggaat gataattact gccgcaccac cttgtttatg taattttatt
     2941 tgctccatag tgtatttacc tttatatatt aagcacctct gaaaccatac ggtattctgg
     3001 tatcaagtcc ttcgctttct ttatctattt tatacgaaaa tcttagcttt gatgctcttc
     3061 ttgcgactct ctcaataatt ttaacttcga gatgattaat ctctgtatat tgatttattt
     3121 tttcaatgtt tttttgcaga aaaaccttat taaaatcctt aaaattctga taaaggtaaa
     3181 ctttttcgcc attatctatt ctgaataatt caagttcatc ctttaataca tctacttcaa
     3241 tgtcgaaaaa tgtcttttta ccactgctgt attgtttcct gataaactga taaagcatat
     3301 ttgaattttg atcagcgagt cttacagacg atatcaaaac ctgagtagtg taagaatcct
     3361 ttaacatcgt gatatatggc tcaatgacat gtgaaaaagc aatatcaata tatccttcac
     3421 tttcaacata atcacaaaac gcagtcaggt tcataagcct gactgcatca gaaggtaatt
     3481 tacctctctt cttcgtatgt ccagagcttt gattgccctg agctgtgaga agttgatttc
     3541 gaggaatgcg aataacacta gcctgaagtt cttctgcccc tcttttaact gccggtaagc
     3601 acctgttaca tcaatatcag cgataaatgc atattcccga gccgtaatac gaaaggttgc
     3661 tccctcagat aactcttcac gtgaatcaat ctgcgccata gccataaaca aaattcttct
     3721 ggcagacaaa ggcaacgatg agaatgtgct gttaatttca tttctgtggc gaatttttgt
     3781 tttctttgta acgctcagta agttcataca ttacctgtgt tttttaagtc ctgatggtga
     3841 aatcataacc acaaaagcgg aaatgtgtaa agtggtttat ccaccttata catttccacc
     3901 aaaacacaga tcacatgaaa gaatttttat catttatatt caatatgata gaaatgcgca
     3961 ggtatccacc ttttaacttt taccgttgga ttggaacgct ataaagaact aaagaaatga
     4021 agatgcaaag agatgaatat ctgaataaaa acagtaaaat gcgtacccat ccacctttca
     4081 gtgcgtaccc atccaccttt cagtgcgcag ccatccacct ttcatgaaaa ttacagtgcg
     4141 tacccatcca cctttcagtg cgtacccatc cacctttcat tttgaggcga caaaaaacaa
     4201 cacctatctt aatgaaatta ttgataaaaa agctggcaca atgtttgcag aataagttaa
     4261 agtaagttaa agatcttaaa gtagatctac cgatctacat ttaagatctt aaaaacaaga
     4321 agtttaataa gcaaaaaaac acaaaaaatc tgtggataac tctgctcaaa acaaaaaatt
     4381 cacagtgcct gtggataact ttgcgtaaac ccagaggaca gatcactctg aaccaggaca
     4441 accacacata aaaacaatat gctcgctttt taaccactgt gcgtaattgc ctgatgttat
     4501 ccctgtgctg ttccgcttcc tcgctcacta actcgctacg ctcggtcgtt cggctgcggc
     4561 gagcggtgtc tcctttctca aaaccagaag agttcagatc atacgatccg ttgattgatc
     4621 ctttttggat cttccactga gaagccctga atcgctttct gcagcttcgt tcagtacaac
     4681 cataagaaaa tccatgtgaa atcgaaaaaa tcgctcagaa tgcgatacag cgcgttttag
     4741 agggtattta caaaacagtc gttgccttga ggaaattttg atcaagattg aactcctatc
     4801 cggatcatag caacaaggcc gctaaaaagc gttgagcggc gttaaaagcc gttaaaccgt
     4861 agctgactac aacgaaacgg gaaaaaacgc tcagaacgcg ttacagagcg ttttaaggcg
     4921 atgtcggaaa gagccatatc tcacctgttc tgatgttttt ctcaacataa gcacttttaa
     4981 gagtgctttt aaagatgcta ttatgccaat gagacaagcg gagggcttat gagctatcaa
     5041 attctgacaa ccacagcggc cagtattact gacctgaaaa aaaatcctat gggaaccgta
     5101 gctgaaggtg aaggggacgc tgttgcgatc ctgaaccgaa acgaaccggc gttctattgc
     5161 gttccaccaa aactttacgc ctactatcgg gaactcgctg aagatgctga gttaaacgct
     5221 gttgctgatg agcgcatgaa aaacccggaa attgtgaagg ttaacctgga tgacctatga
     5281 actggctttt gaccgtagag cactgaagga atggcagaaa ctcggccaca ccatccgtga
     5341 acaattcaaa aagaaactgg cagaacggct ggaaaatcca cgcgtacccg cagcccggtt
     5401 acatggtcat gctgatcgct ataaaattaa acttcgtgca tctggctaca gacttgtata
     5461 tcaagtcatt gatgagaaag tcgttttact cgttattgcc gttggaagaa gggaaagcag
     5521 cgaagtctat cagatcgcag atttgcgcta agattaatca tcaaatgatt gactgtttac
     5581 agtcagagcg agagcattaa aaatttgcaa tacctgcaaa tgcaggtata ataaaacaca
     5641 agaaagggaa acaggttctc tttcatccag agcccaaagt gggcgggagg ttaaaaatgc
     5701 aaaactacgc taaatctgta gccacagaga ttttacgtca acttggtggt aatcgtttta
     5761 ttgttatgac tggtgctaaa agtttttctt actttgatga aaacggtgag tgtgggttaa
     5821 ctttccgttt gccgtcaaat tttgcaatga aaggcatcaa cttagtaaaa attaaactgg
     5881 attttactga tacgtaccag gtgaaatttt ctcgtgtacg tggtgctgaa gttaaagata
     5941 tttcaagatt cgataatatc tattgtgatc agttagcgcg tttatttaca caggaaacag
     6001 ggttacatac cgtgttatag ataaaaaggg gcattaagcc ccttttttag ttatgaggaa
     6061 taatatggat aaagataaga taattaagaa aaacagaggt aattactcct atgtaatcag
     6121 aacgatggat gaagatgggg atacggtttt tcacgtctta aaatatgtta agacgattga
     6181 taaaactaaa agcaggaaaa cagtaagaaa attgataatg gacgaaaaac tcaacctggc
     6241 atcattgatg cttctggata attgggtttt gtgtgattgt ctgacaaaag gggatgaaaa
     6301 tgcagaataa acctacacct gaagaagtaa agaatgcgcg ggttgcggca ggtcttactc
     6361 ttaaagaagc tgctgatatt tttggttatc aactgaattc ctggcagatg aaagaaagtg
     6421 caggtaaggc cagtcgttct ttatctattg gtgaatatca gtatttattg ttattagcaa
     6481 atatgcatcc gtcttacagg ctggtaaaaa aataacttgc catacctgca aatgcaggta
     6541 taataaaaca caggaaaggg aaacaggttc tctttcatcc agagcccaag ctgggcggga
     6601 gctaaaaatg aaagtattaa cttttaaaaa tgatactgtc tctgttggtg atatctttgt
     6661 atcatcatgg ggctatgagc aaaccaatgt aaccttctac caggttcttt ctgttcacgg
     6721 taaaaaaacc gtcaccgttc gcgagattcg cgccaattca gaatataccg attcaatggt
     6781 cggctttaaa actcccgttt taaatgattt tactggtgaa tgttttaagc gtcagataaa
     6841 agattttggt gatgagctgg caatcaaaat cgaagatttt gaaactgcgt ataaaactct
     6901 accggaagaa aaacatcgat tttcttctta ctactaatta atcaggggga tattccccct
     6961 tttagtaaag gtctgaaaat ggaaagagag tttagcgcaa aagcatcatt aaaccgaaat
     7021 ataaaatttt ggtttgagca atgtggatta tctaaagaaa gagttattca ttgtattgat
     7081 aactggtatg accttgcata cccaccatca gaacaggaga aagttagaac aggagaaagc
     7141 aaaaaaagaa gcaattgaga agttaataaa gtaaagataa agatggtatc aggttgtggg
     7201 gcaacctgat accgtgacac ctgattctat tgcgaggaat aaaatgtcgg aacgcatatt
     7261 atcagcaata aatgacgttg aaaagggtgg gcgtccggtt ttccctttga tgccattcca
     7321 tgtctttcct gagtatatgg cattactcag aaaagcactg gaaaaaaaga cacaaaagag
     7381 aacagataaa taaaccggag gctttatgac aaaacatgat tttgtgtcct ttgtcagtgg
     7441 agaattgcgg caaggcgctg tacgcttttc tcttgctttt aacagcaaag gagaaattgt
     7501 tctgcactgg actaataaag caggaatacg agtctggcgg atattaagtg gtaatcgtgg
     7561 caaaaaacca agcaaagcta accttgaaag aatgagtaac ttccggcgct ggctttttga
     7621 tgcccgtcag ggcatggaag gctacactca gcaacctgaa cagagcaacc ttagctgaat
     7681 agccgaagcc ctcccgtatt tcgggaggtg ctttctgata tattgcgcgg gactgcgctt
     7741 gcgcttcctg ccagaccgtt cgcgtagcga acctgacggc actgtcctta ccgcattgat
     7801 cgggtttccg gtcgcagacg tacgtatgtt cagccatgac aacatcagcc tttttgcatt
     7861 tttgttgatg ctcaagcact atttatgagc ggcgccagat tcacggcgat gcaggaaaag
     7921 ctcaacgttg ttattgaaga acgtcgtgaa gatgctgaac gtgaagcggc tgaacgagca
     7981 gagcgtgaac ggaaacgtca ggaactgctt cagttaatcg ccggagaggg tttctcaccg
     8041 gaagaactgc ttggcattac cgaagatgcg ccaaaaacac gtaaaaaaac gttaccaaaa
     8101 gcgccgccca agtatcaatt tgaagaaaat ggtgaaacga aatactggtc tggtcgtggg
     8161 cgtgcaccaa aaccgattgc tgaagcactg gcaggcggtc gctctcttga tgagtttatc
     8221 atcaaaaaag atgcttccag ctctgctggc gacgaacatt aatataataa gcctctggtt
     8281 tacgcaggag acttttttga taaacaggag gatgttttga gtctgacatt accattaatg
     8341 tatttccaga caggtgcaga tctcagcaaa atcacacatc atgaagtgca ctatcaggac
     8401 ggctttgttc agcaggcatg gttgcaacct gaaatacaac tatttgttgt gtgtatcgcc
     8461 aggaaaaaag gctcccgtcg cgagattaaa ggtggaatgg ccgttctgac cagtattccg
     8521 gccagcaatg gagcggagtt ggcaaaagcg ttggataacg ttatgcgcca gtctgatgaa
     8581 ttgcggccac tggcagggaa agacgaaaac gtatttatcc cagccagaat tggaatttct
     8641 ggcgaagaac cgccaacaga gcaagagctt ctaagtgtct tttaccagca atgcctgaaa
     8701 catggctcat ggggcagtgc ttgatttctg ttacataaag cagggatacc ccctgcttac
     8761 ctttcttgcc agcaatatta cgcgctcgat gctctccctg ggcttgatat tgccagggga
     8821 tggcgtcagc acaacccggg gcacgctgat tcgggtgtga ttctgatttg ggacggagag
     8881 gtgtattgct ggaaaaatat tcaccgcgcc cctcagcatg agcgccccag agtgatagcg
     8941 gtagatactg aagataacgt gtttattgca gaaagtggca atgaatatga cggcgcgaaa
     9001 tgctgggttg tctttcagga gtcctgatga tgacgatagc cacagaacgc gctacagcga
     9061 gctacaacag gcgtttgatt tctataacca gcgccttttt gacggtgaac tccccgagtg
     9121 tctgattacg ttccagcgcg tcacacagga tctgtttcag gggaaatttg ctttgagctg
     9181 gtttgatcgc ttctctgtcc aggttgaaca acaaaaagag atggccgccg tcatcgaaca
     9241 atggcgggaa actattgctc aggcacatca aaatgctgaa ccgggattga tattgaagcg
     9301 gtgctgtcag tgtcaccgta gaacgggagc aatgataacg atctgtttgt tgcggctttt
     9361 gagaacaagc caaaaaggaa caaagtcaaa tatcagtgtc ggggtgtggt gctgctgtct
     9421 gggagaagtc cggactgaat attgaatgcg gcgattgcga gctgcctttc atcgaaaatt
     9481 aatctctatt ttcattgtat ttcctgatgc tttctcataa gttctcgtgt ccaatcccac
     9541 ccgaaaaaac tcagatttca cgtagcgcac caccgctcat tgagcggctt ctcaacgtga
     9601 ctggtaatca ggattattgg tttccaatgt aatgaacgat ggatgtatca aattctttta
     9661 ttgcataata gcatatttat tacaaaatga tttaaacgca gatgattata ttctgtatgg
     9721 ttatttatgt ctaaatatat aaattaataa attttagaat aaaaatgtag aatcgcaaat
     9781 aatatgattg tgctgttctt tttttgtgaa ataaatctat gtttgtatat ttttataagg
     9841 aatattgttt tttatagtga taaaaacact tgtgaattaa tcacagtaat aggaggcgta
     9901 aaatgcgtac tggtaatgca aactaatgga aaaatataaa tgtccattaa atgccaccct
     9961 gtacagggtg gcatacaaaa gttatctgcg aggtttattt atggattata tattgggtcg
    10021 ctatgtcaaa attgctcgat acgggagcgg tggattagtt ggtggaggcg gaaaggagca
    10081 atatgttgag aatttagcgc tttgggaaaa tattataaaa accgcatatt gtttcataac
    10141 cccatcgagt tatactgcag cgttggaaac ggccaatata cctgaaaaag atttctctaa
    10201 ttgctttagg ttccttaagg aaaatttctt tattatacct ggcgagtata ataactctac
    10261 tgagaataat cgttactctc gtaacttttt acattatcaa agttatggtg ctaatcctgt
    10321 tcttgtgcaa gataaactaa aaaatgctaa ggtagtaatt cttggttgtg ggggtatagg
    10381 aaatcatgtg tctgttatac tcgcaacgtc tggtattggc gaaattatac taattgataa
    10441 tgatcaaata gaaaatacaa atttgacaag gcaggtttta ttttcagagg atgatgtcgg
    10501 taaaaataaa acagaagtta taaaacgcga gttattaaaa agaaactctg aaatttcggt
    10561 gtctgaaatc gctttgaata taaacgatta cactgatctt cataaggtac cagaagctga
    10621 tatatgggtt gtttctgcag atcatccatt taatctgatt aactgggtta ataaatattg
    10681 cgttagagca aatcagccct atataaatgc tgggtatgtt aatgatattg cagtctttgg
    10741 tccattatat gttcctggta aaacaggatg ttatgagtgc caaaaagtcg tggcagatct
    10801 atatggttca gaaaaggaaa acattgatca taagattaag ctaatcaata gcagatttaa
    10861 accggcaaca tttgcacctg tgaataatgt tgccgctgca ttatgtgcgg cagacgtaat
    10921 taagttcatt ggaaaatact ccgagccatt atcacttaat aaaagaatag gcatctggtc
    10981 agatgaaata aaaatacatt cccaaaatat gggccgttcg cctgtttgct ctgtgtgtgg
    11041 aaatagaatg tgaatactgc aaatatttta tctgtgaact atggagctta taatgctata
    11101 cgtatgttaa ttggtgtcta ccatgcagca tttcttatat ctacaggtgt cactatatct
    11161 caacttgctg ttttacagat cgttttttct gtgacagtgc tgattcttga ttttccttta
    11221 tctgtcattg cagacagatt ttacaggaaa caggttgtag ttagtggcgt attttttact
    11281 atattatttt accctctttg tattcagtct cctgatatgc tggcattggt tttttctgaa
    11341 atattttatg ccattggtat ttgttgtata tctggggcta tagagggatg ggtgttaagt
    11401 gctctggatg gtagaaatga aaagtttacc ttatgtgctc atttatgcga aagggtatct
    11461 tcctttggga gtgtgataac tggtgctgtt ggaatattag ttgtctactt ctatgattct
    11521 tataaatctg gctatatagt atcgttcttc ttgatgtttg ttgtctttat cgttttttta
    11581 tgtgtgaaaa ctaatggcag tggaggtgaa aaagaagcac gagatagtat tattaaacag
    11641 gcaaaagaga gtattggatt gataacagga agttataatg ggacatattt tttatctata
    11701 acatgtatgt ttacaattgg tatacaggta atttatcatt tttggcagcc aattatgcta
    11761 tctggggaaa gtattggctc attatcaaaa agagagctta taactttact gatgtgtcat
    11821 attggtgcat tttcaatgca atatatagca aactatctta tgccaaagat agatgtaagg
    11881 tgtaaacttt atatacttgt ttgtacatta tgttcatttc ttagttcaat cgcctgtatt
    11941 ttactattta tgttaataac agataataag gttgttctcg gcgtagctat tttctctata
    12001 atccatggga tgatttcaac aatacctgtt ggagcacaga atatattcat aagcagactt
    12061 aatggcaatt ataagaatat tatttcggga gctcttggtc ttgtttctct ttcatgtcgt
    12121 gttgcttcca tttctgtgtt gggagttata tctgtattac caggtaatat gcctgtcacc
    12181 acttatatat ttatctctgc aattgcatgt gtactgtgcg gttgtttgtt cttaatgtgg
    12241 tcctttaaaa aggagatggt atgacgatta aacatgctga agaattgacg gaagaagtta
    12301 ttttaaatat gaattaccct gattttgttg ctctgatgca acaggataac actcctcctg
    12361 gagcagagta caccatagac tactggatca agcatggatg tattaacaaa aagtctcacc
    12421 tattagattt agcatgttcc acgggtttta gttcacgtga atgcttcaaa aaagaaggtg
    12481 catctgcaga gggtattgat atatctgaat cagctgtaat ggtcgcaaat gaaaaggcaa
    12541 aaaagcttaa ggctaataat ttattgaaat attatgtagc tgatgcttgt gatttaccat
    12601 ttgaagataa ctcttttaca catgttctcg gtggatgtaa ttttgcattt atacaaaatc
    12661 ggttaatagc tttgaatgaa actcatcgat gtttaaacca catgggaagc atgtgcattt
    12721 caaattttta ttacaggcgt aaaatatcag ataaacttat caatgatgta tataatgcaa
    12781 taaatttcag acccaatcct ttgtggactt tggaatactg gcatcagttt ttttctgaaa
    12841 gatttactct tgtttcagaa gaaaaccatg agatggaatc tcaaagtgaa gatgagttaa
    12901 aagccgatat ttatgattac attttcaata gaaatgagtt tacaaaaggt ttgaatggtt
    12961 cacttcagaa tgtatttttt gaaagatttt taaaaatacg cagaccatta aatatccaaa
    13021 gagattatca gggagttaca ttgcaaatat ggcgcaaaaa ataacaccat ctaaaattgt
    13081 taaacatgcc cgggagttaa ttattaaggg gattgaatcg ggcgaaaact catttgtcat
    13141 ttttgatgta gatggagctc tggagcgtct ggatcattac aggtgtcaac ttaagagttt
    13201 tttccccaac agtagtatcg catattcata taagtcaaat aatctggcac aatggtgcca
    13261 gattatctca ggtaaaggtt tgtatgcaga ggtgtgctct gttgatgaaa tgaacctcgc
    13321 caaaagagac ggttttaagc ggattgtttt tgatggccct ttaaaaaaaa cgagtgaact
    13381 attaaaggca atagagattg gggcattaat tgaagttgac aatattgatg aatgtaaaag
    13441 acttaatgaa ctatgtaagt tgcataagct gacatgtaga attcatttga gattatcgca
    13501 ttactatgat gataatttat caagatttgg cttatctgaa agtgaggcta ttaatttact
    13561 ggagatgttg atcagtaagt cagagtatct cattttagac gggttccatt tacatgttgg
    13621 ctctaatcta cccaatgcgg aaaaaatatg taaagctatt atacagtatc atgagttgat
    13681 tcttaggtat atgccagatg atggcactct taatcttggt agtgggatac ctgcagattc
    13741 tttctcagca tccagtgata acccaactcc atgtccggag gtatttttct catcgatata
    13801 tgatacaata aaaaattgct tcggtactgt atgtgataaa tggaactata tttttgaacc
    13861 agggagacat ctggtcgaag actttggcta ctttataggg aaagttatta gtactaaaaa
    13921 caggtatggt gttaaagttg ctcaaactaa cattggtata aactggatac cttcgatcag
    13981 aaattgggac cattcattta cattgtttca taatcataac catatttcag atgataaatc
    14041 tgatgagtat attattgctg gattcaattg ctttgaatgt gattgcttgt ttccttcagt
    14101 tattcttccc agtaacttat ctgattattt attttctgtt cgagggtgtg gtgcttatga
    14161 tatgcaaaca ggaaaccagt ggacgcgtaa tctttatgct gtatatacca taacaaatga
    14221 tgttgttaat atatcaagga ttcacagaag agaacttgat ttccggaagt atgatgtatc
    14281 tcttacgcca tcaggaataa aagtaaatga tgaaattaca ttattgtatc cagcgttaaa
    14341 atacgctgaa gagttatatt tgctcattaa tcaaaacaaa ataaatttca ttaaaagcat
    14401 ggcatggcca gcgtttgtta ataacatttc tgattctgtt tctttcattg agcaatcaat
    14461 gattgataac cagaatgaaa aagcattaat cctctttatt aaatacaaaa ctaagatagc
    14521 tggcgttgta tcgtttaata ttattgacca tgccaataaa acagcatata ttggctattg
    14581 gttaggtgct aactttcagg ggaaggggat tgtaaccaat gctataaata aactgataca
    14641 ggagtatggg gattcgggcg ttataaaaag atttgttata aaatgtattg ttgataataa
    14701 aaaaagtaat gccacggcat tgaggtgtgg cttcacctta gaaggtgttc tgcaaaaagc
    14761 agaaatactc aacggtgtat catacgatca aaatatttat tcaaaagtaa ttggttaata
    14821 ctgtatggcg tagtattcta cgccattttg tttatgtctg tgagatgata atatttattt
    14881 ctcggtagat agatattgtt ctgttataga tatatttttg ttgtcaaagt caatagctaa
    14941 ttttacacca agtggaagag ttagcattgg atgtgtatgt gaacaatcaa atccatccag
    15001 tacaggaatc tgtttcccat ctaatacctc tgttaatact tcatatggtc tgcgtttact
    15061 tcctgcacaa tcaaaaagct catgtttccc gagtattatt gcactaactt tatcaaacac
    15121 gcgattaagc tttagcatag agaataatcg ttcaattgtt gcaatgcttt tccgactgtc
    15181 ctcaataaac aatatatctc cattaagaat ttcaggcatc cattcactcc cccatatacc
    15241 tgtcaaagta tttagatttc ctccaattac acgccctcaa cttttccgga accataaaag
    15301 gcacagttgt ttttatatag cttcttaggc cttaatatct tgttttcatt ccagtttatg
    15361 ctctcatcac tccacttttc aggtaatgtg taggtatata ttcctgattg ttttcttgtt
    15421 agtattttaa taaatgattc atatgttata tccacaagag gtggatgttc accaaacgaa
    15481 ggaataagag ctggtccata gaatgttatt aaccctgttt ttgcatatat tcctgctaat
    15541 aaagcagttg tatctgagta acctatgata attttggggt ttgcaatgat agcatcatag
    15601 tccagaaacg gtagtagtga attactgtta tctccaccga tcgttgacat tatacaggta
    15661 atatcaggat tgtagactaa ctcattaaat tcttgagctc tttctttaat agtacctgaa
    15721 cgataaaaat ctgttttacc ggtaagcttc cctgatacca gcttaaatcc ctttctctga
    15781 agaaactcaa ctccccgaaa aaaacgattt tttgcagtaa ctgttgccgg agcagatgat
    15841 gaaaagaaac caattgtatc tcctactgcc aggggagcgg ccagtagtgg atgagattgt
    15901 atcatcatga ggatttttcc tttccattta gtgtcaaaat gaacccgttt tgagatatgt
    15961 cagtagcact ttcagtttat gggctttttt gaaaatcgca gtgttctctc gtaaattttc
    16021 tcgtccaatc ccccccgaaa agcctcagat ttcacgtagc gcaccgccac tactgtatcc
    16081 atcaaaaaaa ctgatagctt ttttaatcat ctgttgtgct gcaacttact gaaaaaaatg
    16141 gattcatgaa aacgccgata acggtattga tctgttggcc aacgcgatca gcagtattgg
    16201 tcgcaacaaa aaatgaaaga aaaatccctc aaatgaaggg gaaaaaacgg aagtacagct
    16261 gaacgacagg cacaaaaaaa cccgactggt aatcgggctt ttttgtgttt tccagccctg
    16321 agttggtggc tctgactgga gaaggttact ctacacctaa cgtttacatt ttattcacta
    16381 tggtgctgta aagcaactaa atgtggttaa ggaaccacat ttagtggtgt aacgggtgtt
    16441 ttgtgtagcg tataatcagt cagttagtca tgtagttgac ttgcaatcct gctcttcccg
    16501 tatctgcggg tatgaacgat tttaaagtcc tggctggata aacaggtggt gctgtattcg
    16561 gtgctctggc aggaggaggt cactctacac ctaacaatgc gagagagccg ttgtgacagg
    16621 cagtgtatga gtaagcaacg gtgatttcct ccagttttac tggagaaacg gatgattaat
    16681 ttgttaatca tcgttctcag ggctgtggtc gccgttgcaa acgcgctgat tgcaattctg
    16741 gaactgattc gccagttcat cgactgatga cagcggaaac gtaactaagg gcaggaagtg
    16801 aaccgcttcc tgccctttaa caaaggagga tttatggatt ttatgagcat tttggggcgc
    16861 tgtttacttc ttcctttccc tgttgcgatg tttgtcggtt gcctgtttct aggcattgat
    16921 gatcgtttta ctggaatgtt catgagtttt attgtcggtt gtctatcgtg gtatatcacc
    16981 aagccaaaac cgcaaaaggc tgaggtcgcg taagcggctt ttttacgccc ctcgtttaat
    17041 tcctcgcccg acttggatat acactcattc tgtccagaaa tagtattgcg gctaatcaag
    17101 ccaattccta cgtcttttcg ctgttgcacg atctaaaaga aaatatggga aaatttcatg
    17161 aaagtatggt actaaagggt ctttaattcc tttatcttgt tccttcaact gcacagtatc
    17221 tcgtaaaaac caacaagccg gttgtttaaa aaacgctctt agcgtaggat gttttccatt
    17281 ttccaagtga aacccaagta cgatgcccgc gaaaagacag ccctttatga agagggctgt
    17341 tatctgatat aggcttgtta tggtctcact cttgattaat caggtgtatg tacaaccttg
    17401 gtgtacacaa tcgattatgc agcttgatga tctgaagtgt taccggaagt atcttcggtt
    17461 cgttttttgt ttgtgatgga ttcactttta tctcgcaagg ctgagtctat gacgttaaac
    17521 accttttccc accgagaaat ccaaccgcat ataggttgaa cacgacatct ttccaggaag
    17581 aaatttaata agttagtttt tttattatct tgcactttga atggttcaat tacatcatcg
    17641 gcatcaacag attttcctcc gataaaccac gacggatggg tttccattgc gtcagaaatg
    17701 aaatcgtcag ggaagaggcc ttcaatagca aaaccacttc ttacagaaat atagtcttta
    17761 tttgactcaa atctaatttg ttttttacca aagtagcttt gtaatctggt tctttctttg
    17821 acccagcttc atcaccgtca aaaacagata ttacggggac atctttagaa ataaactcgt
    17881 agcacccttt caagaatcct ccaagttgac tgactccacc aaactcatca actttagcac
    17941 tcctcaaaaa ggccatctgt tcttaaactc atcatgttca gatgtcaatt tcaatattga
    18001 ttctatatat tgtttgtcgg tgataccttc aacgaaactg cactacttga tatgttaaag
    18061 aaatcagaaa atctgacccc aagattttct cttatgcttg caactgcatt aaatcttttt
    18121 tcatgctttt tatcttttgt aacaccggcg tcatctttat ataactcaat gatcttactt
    18181 ggctcatcac tgacaaatga taaggaatga gttgtaataa gaacataagc aacatccatc
    18241 agtgatttga aaatgtgatt acatgaccgg cctaatgagg gatgcaagaa agactcaggc
    18301 tcctcaacca tccaaatcgt tttcttacct agagtaagtt ttctctctga aatagattta
    18361 aatgaagaaa ataaagataa gcattgtagc cccatacctt tactcgatat cacattctca
    18421 atagtatctt ttattgaaac ctcaaagcga ccaaataact catcaagaga tggcggagct
    18481 ttaatcataa agctacagtc atctataccg cttagaatca tttcatttgt tatcttttca
    18541 gacacttcca acagtttatc atgaatcact tgaaccgatg ttttcatggc tgaagctact
    18601 tcactcctaa catatggaac taatagatta tgatatatat catcaatact ttttgacgat
    18661 ggtatataca cacactcaaa actagaaagt atttttttct atgaaccttc tttcaacaga
    18721 tgtatacatg gaggaagtta cttcaggttt cctcttgtaa cctttaaaga cagtgtagaa
    18781 gtaattgttt ttattagata ttgtcagatg tacggtcact tcgttttgag gtgaacttaa
    18841 cctggagtca tcaatcatgt taaatagctg caaatatcta tctctcaaac ttagctttct
    18901 gcctcttgat tgagttggtt ttgattcttg ttgtttagag ctgccatcat caaatgaaat
    18961 agaattacta ggttcttctt gcccccctaa aacaccaagt tcaataatcg agtcatcatc
    19021 gtcatcatca tcgtcttggc tcaaatcctc agagacatca tctagctcac tttcagaaaa
    19081 agtaaatctt acagcaaaac tagtttgtcc ttgcttaaca ccatgtggct tatctttttc
    19141 atagtcatat aagtcaggat taaattttcc ttcaaaaaaa accctcatag cttttaatag
    19201 gtttgtttta ccactgttgt tttgcccaac aatggttaat ccattaaagt tatcagagga
    19261 tatctcccct gaaatagacc tatactgaga aactttaaat gatactattt ccatttttct
    19321 tcctacgata gaatgttgct cggattatcg acattttttc ccaaggcttt aactgtcctt
    19381 cgctacttgg agaaatggct cttcctccac tgttctgctt tattttcgcc agaaagccca
    19441 ccatgcatgt tgtttgtcct gaagtgctgc tttatcctga agcaattcag cactcactgc
    19501 cccctgaagc acagaaacgg cgtttctcgc ggcattgcga caggaatcaa taacctctgg
    19561 ttcgttgggc tttctgagca ggataaattg cgatactttg gactgagtat caaaagcata
    19621 gattcgcaat tcaggggagg atgtcaggct tacaatatta tgtaaccgca tataattggt
    19681 gtagtcctcg ctacctggat tacatgattc ataaagatat ttctgcatta gcgtttgcga
    19741 tgaagaaaga aaatctatat agcggtcagt ttttttatct atatcccgca gtcgctgagc
    19801 tattgcatct tttcttattt cgtggcagtg tgttaatttc agtgtaatcc agccaccaac
    19861 aatggtgatt aatgcaccca gcccaatttt aacggcatta tcagccacat ctacccactc
    19921 agttgccatc tgttacacgt tcttcctgtg atgatcatgg tcgctagtat aattctccgg
    19981 ctgactggac atacagcatt ttctgtctag caccgaaacg ttataaacct ttgttcaaat
    20041 tcctgatctc tggcatcatc ttttcgtaca tcttttcagt tgagttagcg caataactct
    20101 gtaggtattt atagttttct tcgaatttcg gaaggttttt agctaaagtg atctgtttag
    20161 gtaaggttcc ggtagaatcg ttgaccacat caaacactat cggattatgt ttatgatctt
    20221 catcaactaa ttttaatgta gctacaacag ggcttttatc cattgcccgt taactagttg
    20281 tctaatttgg aattttctcg caaaaataaa attaattaga gatggactgt cactattaaa
    20341 agttatattc cacgtcaaag gcattgcatc acataatcct tctgagataa attcaccatc
    20401 aatagaacca tctttatcaa caaataattg tatagtcata attgattgcg gtttatctag
    20461 tccaagatcc ccactattaa taatatatca gcatctgttg accattttcc ggtaaggaat
    20521 tctctttgat aaagagcagc attcaattca tttttatatg gtaggtaaag tcccactgct
    20581 gcgataacca ccccaaatgc agtgcataag gttgtgattc gtccactcat ttttttccct
    20641 tatcttcata tgtaaaattt ataacc
//
