LOCUS       NZ_CP021543.1          15271 bp    DNA              UNK 01-JAN-1980
DEFINITION  NZ_CP021543.1 Klebsiella pneumoniae strain AR_0047 plasmid
            tig00000004, complete sequence.
ACCESSION   NZ_CP021543
VERSION     NZ_CP021543.1
KEYWORDS    .
SOURCE      .
  ORGANISM  .
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-06-07 20:38:17
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             2..736
                     /locus_tag="ctg1_1"
                     /transl_table=11
                     /translation="MDAAHPEEGLKREYDKAKAELDAEDKNIATLNSRIASTEKAIPGA
                     RAAVQEADKKVKEAEANKDDFVTYNPPHEYGSGWQDQVRYLDKDIQNQNEKLKAAQTSL
                     NEMNESLSRDKAALSGAMESRKQKEKKAKDAENKLNEEKKKPRKGTKDYGHDYFPDPKT
                     EDIKGLGELKEGKPKTPKQGGGGKRARWYGDKKRKIYEWDSQHGELEGYRASDGEHLGA
                     FDPKTGKQVKGPDPKRNIKKYL"
     CDS             746..1003
                     /locus_tag="ctg1_2"
                     /transl_table=11
                     /translation="MGLKLHIHWFDKKTEEFKGGEYSKDFGDDGSVIESLGMPLKDNIN
                     NGWFDVEKSWVSILQPHFKNVIDISKFDYFVSFVYRDGNW"
     CDS             1878..2006
                     /locus_tag="ctg1_3"
                     /transl_table=11
                     /translation="MEKRHLRGLAVLPHMLVPCLFTESVGNFACVRSARRSLTAGA"
     CDS             2718..4682
                     /locus_tag="ctg1_4"
                     /transl_table=11
                     /translation="MFNTDSLAWKWHIPELARQIYPWVSWLYQEYYGLAGAFLVIGLFF
                     GLAELWAGRMRFVGLSHKERREYADRYKRDNKRPAPFSVLASLDSPGRMVRARRHVWNY
                     AYWLTGAAGLALLGGLVVAVFIESWGETVLRPDLYANADYYLLQPANLFGIAWCAGGLA
                     VGIVLARLLAFLLLDGHFAAADEAVNAKLNQESRRSSQRTGEMTDVRHLHFGEPVPVNA
                     LADFSSEQARQEQAVFLGKDEQGKPVLVPRDTWRKTNIQILGLPGSGKSVMATNALIRC
                     VRDFGDAVVYFDPKGDAWAPHVFRAHCPDFTLLDLRPGKPAQLNLFRDLDQYALKNLLI
                     AGLNLGETGDVADHYRISEQKAAKLIAEQFPQGANIQQVLAAAYALPEALKKDVKGLIT
                     RLENVADLSVLQTDSGIDVAGIINGGGCLYVIGSMDDEAVIRVQKMLFARCAQIIIARD
                     EFREWPHVSVMLDEIKYLLSKYVLNALGTLRSRDCNLLLAHQSLGDFGQCGQDLPAEFV
                     KTTVLDNTPIRWFYRAASLESAQWAAGQTGEIRVDVERRRASREAGNVEHISGDSFIQK
                     EARPLFDVNTLQHLPDGFAVMTGLGVARMAFSSPLRVERREIPLQRFPVLAKTDPLAEF
                     RPPADGGGPKADDDFAGIY"
     CDS             4682..5413
                     /locus_tag="ctg1_5"
                     /transl_table=11
                     /translation="MALELYNVSHAKRQARNAEKTRLTLRWLREELCSTAELVARRLGI
                     AAVQPVYRFLDSLVAKGLLVRTKYPVDGRQVSVWGLTPHGVAFSFDEDEPLADVIPFQP
                     SRVSAAHLPHRLAVQSLRLDMEARGATGWRILHRLSLKGMKVPDALAELDGKTVAFEVE
                     RTVKSRRRYQEVVSGYLFNRKANGIDEIWYICPDRATQVRVQRAILSVDEIVNPQTGEA
                     RKTAELDRERLFACFKFMTTE"
     CDS             5420..5950
                     /locus_tag="ctg1_6"
                     /transl_table=11
                     /translation="MALYMVFIEDAEDRNGERCIMPTSEHLEDMVVLAWQTGAYVFCFV
                     DRAQHLAMMKSIGMYDERLNSDEKATYFFTGKNPQWERNKPTGMKLCDYLYRKVERFAI
                     ENGVQVVDAGKCSPEQINAMIDVVSERHGESAVNEKLKAELMREYNSRYFNVPVPELPE
                     DKPARRWWPFGKK"
     CDS             complement(5978..6157)
                     /locus_tag="ctg1_7"
                     /transl_table=11
                     /translation="MTKQEKTALNMAKFIKEQSLLLLDKLNELDMDTPADMCERLHEDA
                     ETLWQVMRDKLGEE"
     CDS             6226..6603
                     /locus_tag="ctg1_8"
                     /transl_table=11
                     /translation="MAWVTVRQATELTGKARSSLYRDMAKGRVSYRTEADGGRVVDTSE
                     LIRVYGELRQDETHERDELRLSGETEKMASDALIAEIKALREEVAGLRQEMQSMRLLEH
                     KPETAETPAGTPRRWWPWGKR"
     CDS             complement(6665..6964)
                     /locus_tag="ctg1_9"
                     /transl_table=11
                     /translation="MPYDVEWKQGAIEDVTTLFDYIAENSSLWDAQNVTDRVLAAADKL
                     ADFPRLYEVDSRYGEDVRRISLMGQHVLYDVDDQTRKVRVLAVVGQRQNPHIVL"
     CDS             complement(6954..7217)
                     /locus_tag="ctg1_10"
                     /transl_table=11
                     /translation="MSNTTHYENANFLRELAESLPRILPEGGPDKAALLQRLANEELAQ
                     AEYEDQVRAKVTAARADTRPGMTTEQLRQRLHGRYQELRDAV"
     CDS             complement(7523..7942)
                     /locus_tag="ctg1_11"
                     /transl_table=11
                     /translation="MRRSGSKLCLIAMITATATLTACAPKGSVEQHTRHYVYASDDGFD
                     PNFSTQKADTTRMMVPFFRQFWDMGAKDKATGKSRSDVQQRIQQFHSQEFLNSLQGTTQ
                     FAGTDYRSKDLTPKKSRLLADTISAVYLDGYEGRQ"
     CDS             complement(8019..11024)
                     /locus_tag="ctg1_12"
                     /transl_table=11
                     /translation="MPVDFLTTEQVESYGRFTGEPDELQLARYFHLDEADKEFIGKSRG
                     DHNRLGIALQIGCVRFLGTFLTDMNHIPSGVRHFTARQLGIRDITVLAEYGQRENTRRE
                     HAALIRQHYQYREFAWPWTFRLTRLLYTRSWISNERPGLLFDLATGWLMQHRIILPGAT
                     TLTRLISEVREKATLRLWNKLALIPSAEQRSQLEMLLGPTDCSRLSLLESLKKGPVTIS
                     GPAFNEAIERWKTLNDFGLHAENLSTLPAVRLKNLARYAGMTSVFNIARMSPQKRMAVL
                     VAFVLAWETLALDDALDVLDAMLAVIIRDARKIGQKKRLRSLKDLDKSALALASACSYL
                     LKEETPDESIRAEVFSYIPRQKLAEIITLVREIARPSDDNFHDEMVEQYGRVRRFLPHL
                     LNTVKFSSAPAGVTTLNACDYLSREFSSRRQFFDDAPTEIISQSWKRLVINKEKHITRR
                     GYTLCFLSKLQDSLRRRDVYVTGSNRWGDPRARLLQGADWQANRIKVYRSLGHPTDPQE
                     AIKSLGHQLDSRYRQVAARLGENEAVELDVSGPKPRLTISPLASLDEPDSLKRLSKMIS
                     DLLPPVDLTELLLEINAHTGFADEFFHASEASARVDDLPVSISAVLMAEACNIGLEPLI
                     RSNVPALTRHRLNWTKANYLRAETITSANARLVDFQATLPLAQIWGGGEVASADGMRFV
                     TPVRTINAGPNRKYFGNNRGITWYNFVSDQYSGFHGIVIPGTLRDSIFVLEGLLEQETG
                     LNPTEIMTDTAGASDLVFGLFWLLGYQFSPRLADAGASVFWRMDHDADYGVLNDIARGQ
                     SDPRKIVLQWDEMIRTAGSLKLGKVQASVLVRSLLKSERPSGLTQAIIEVGRINKTLYL
                     LNYIDDEDYRRRILTQLNRGESRHAVARAICHGQKGEIRKRYTDGQEDQLGALGLVTNA
                     VVLWNTIYMQAALDHLRAQGETLNDEDIARLSPLCHGHINMLGHYSFTLAELVTKGHLR
                     PLKEASEAENVA"
     protocluster    9322..15271
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[14321:15269]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      14322..15269
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    9322..15271
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          9322..15271
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             11186..11743
                     /locus_tag="ctg1_13"
                     /transl_table=11
                     /translation="MRIFGYARVSTSQQSLDIQIRALKDAGVKANRIFTDKASGSSTDR
                     EGLDLLRMKVEEGDVILVKKLDRLGRDTADMIQLIKEFDAQGVAVRFIDDGISTDGDMG
                     QMVVTILSAVAQAERRRILERTNEGRQEAKLKGIKFGRRRTVDRNVVLTLHQKGTGATE
                     IAHQLSIARSTVYKILEDERAS"
     CDS             11926..12531
                     /gene_functions="resistance (resist) AAC6-Ib (Score: 433;
                     E-value: 5.6e-133)"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1203:putative siderophore biosynthesis protein (Score:
                     62.9; E-value: 6.5e-19)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_14"
                     /transl_table=11
                     /translation="MSIQHFQTKLGITKYSIVTNSNDSVTLRLMTEHDLAMLYEWLNRS
                     HIVEWWGGEEARPTLADVQEQYLPSVLAQESVTPYIAMLNGEPIGYAQSYVALGSGDGW
                     WEEETDPGVRGIDQLLANASQLGKGLGTKLVRALVELLFNDPEVTKIQTDPSPSNLRAI
                     RCYEKAGFERQGTVTTPDGPAVYMVQTRQAFERTRSVA"
     CDS             12613..12870
                     /locus_tag="ctg1_15"
                     /transl_table=11
                     /translation="MIAEVSTQLSEVVGVIERHLEPTLLAVHLYGSAVDGGLKPHSDID
                     LLVTVTVRLDETTRRALINDLLETALLQIVGGDKLIIPFC"
     CDS             12882..13586
                     /locus_tag="ctg1_16"
                     /transl_table=11
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTVDF
                     YLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDVEHR
                     QIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYYGDPL
                     GEMRLVSRVFEM"
     CDS             14322..15269
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Cloacin"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_17"
                     /sec_met_domain="Cloacin (E-value: 5.1e-114, bitscore:
                     369.2, seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGGDGRGPGNSGLGHNGGQASGNVNGTSGKGGPSSGGGTDPNSG
                     PGWGTTHTPNGDIHNYNPGEFGNGGSKPGGNGGNSGNHSGSSGGGQSSATAMAFGLPAL
                     ATPGAEGLALSVSGDALSAAVADVLAALKGPFKFGLWGIAIYGVLPSEIAKDDPKMMSK
                     IVTSLPADTVTETPVSSLPLDQATVSVTKRVADIVKDERQHIAVVTGRPMSVPVVDAKP
                     TKRPGVFSVSIPGLPSLQVSVPKGVPAAKAPPKGIIAEKGDSRPAGFTAGGNSREAVIR
                     FPKESGQKPVYVSVTDVLTPAQVKQRLEEEKRRQQ"
ORIGIN
        1 atgggacgct gctcacccgg aagaggggct gaaaagagag tatgataaag cgaaagctga
       61 gctggatgct gaagataaaa atattgcgac cttaaacagt cgcattgcat cgacagagaa
      121 ggcgatcccc ggtgcaaggg ctgctgttca ggaagccgat aaaaaggtaa aagaggcaga
      181 ggcaaataaa gatgattttg tgacttataa cccgcctcat gaatatggct ccgggtggca
      241 ggatcaggtt cgctatcttg ataaggatat tcagaatcag aatgagaaat taaaagctgc
      301 ccagacatct ttaaacgaaa tgaatgaatc cttatccagg gataaggctg cgctttccgg
      361 ggcgatggag agccggaaac aaaaggagaa aaaagcgaag gatgcagaaa ataaattaaa
      421 tgaggaaaag aaaaaacctc gtaagggaac taaagattac ggccatgatt attttcctga
      481 tcccaagact gaagatatta aggggttggg agagttgaaa gagggtaaac ctaaaacccc
      541 taaacaaggt ggtggtggta agcgggcccg atggtatggt gataaaaagc gtaaaattta
      601 tgaatgggat tcccagcacg gtgagcttga agggtaccgc gccagtgatg gcgaacacct
      661 cggggcattc gatccaaaaa cgggtaagca ggttaaaggg ccggatccaa aacgaaacat
      721 taaaaaatat ctttaagagg taaatatggg gcttaaatta catattcatt ggtttgataa
      781 gaaaaccgaa gagtttaaag gtggtgaata ctcaaaagac ttcggtgatg atggttctgt
      841 cattgaaagt ctggggatgc ctttaaagga taatattaat aatggttggt ttgatgttga
      901 aaaatcatgg gtttcgatat tacagccaca ctttaaaaat gtaatcgata ttagtaaatt
      961 tgattacttt gtatcctttg tttaccggga tggtaactgg taagcaaaag ttatcaagga
     1021 tgatttgaaa tacagacttc cggtgttcag ggatgaatac cggggttttt aaatacaggg
     1081 aaggtatatg aaaaaggtaa aggttgtttt tctttttata ttgatttttt caggctttct
     1141 tctggtcgca tgtcaggcaa actatatccg ggatgttcag ggtggaacgg tggcaccatc
     1201 gtcctcctct gaactgacgg ggatcgcggt tcagtagaaa agatcaaagg atcttcttga
     1261 gatccttttt ttctgcgcgt aatcttttgc cctgtaaacg aaaaaaccac ctggggaggt
     1321 ggtttgatcg aaggttaagt cagttgggga actgcttaac cgtggtaact ggctttcgca
     1381 gagcacagca accaaatctg tccttccagt gtagccggac tttggcgcac acttcaagag
     1441 caaccgcgtg tttagctaaa caaatcctct gcgaactccc agttaccaat ggctgctgcc
     1501 agtggcgttt tgcgtgcttt tccgggttgg actcaagtga acagttaccg gataaggcgc
     1561 agcagtcggg ctgaacgggg ggttcttgct tacagcccag cttggagcga acgacctaca
     1621 ccgagccgag ataccagagt gtgagctatg agaaagcgcc acacttcccg caagggagaa
     1681 aggcggaaca ggtatccggg aaacggcagg gttggaacag gagagcgcaa gagggagcga
     1741 ttcatcggaa acggtgatga tctttaagtc ctgtcgggtt tcgccactcc tgactgattc
     1801 atggttgagc caccggctcc cacagatgca ccgaaaaagc gtctgtttat gtgaactcag
     1861 tcaggagggc ggagcctatg gaaaaacgcc acctgcgtgg ccttgccgtt ttgcctcaca
     1921 tgttagtccc ctgcttattc acggaatctg tgggtaactt tgcatgtgtc cgcagcgccc
     1981 gccgcagtct cacggccgga gcgtagcgac cgagtgagcg aggaggcgca atttccccgg
     2041 cacctacaag acggacaccg gacgcgctga tgtggcatat tgtcccctga ttaagtcttt
     2101 atattccctg ataataaatt accaggatag gtgaatcata tcggtttttc gctgaacatt
     2161 ttacgttaac ctatctctgt tgcttttttc tccttacgga gaaatacagg tcatccccgc
     2221 gagggcgtgg ctgacctcag ggggatatcc cctgcttacg ctggctggac gccaccgacg
     2281 cacggtctct ccccctcttt ctggctccgt ccggctggac gccggccacg ccagaaattc
     2341 acccggcccc cgtcaggctc acgcctgacc acccacaaaa atccacggtg ctggacgcac
     2401 ctggcgaagc agcaaagctg ctcctgattt tgcgggtggt cagccgctcg ctatggcgaa
     2461 ctctgacggg ggccggaaca ccggaaaaga ccgcactggg gtgccgcctt ttcctctcac
     2521 acgctggggc gtgctcgttg ttcctccggg gctgcgcctt ttccgcatgg ggcggaaaga
     2581 ggctggcctc cgtggtgaaa gctgaacgca atcaccacgg acgtgaccgc cgccgccatg
     2641 ccttggggca tgtccgcggc ttgtgcagcg ggggctgcac atcacgccgg caaaccatcg
     2701 tctgaaggag agagaacatg tttaatacgg attcgcttgc ctggaagtgg cacattccgg
     2761 agctggcccg gcagatttat ccgtgggtca gctggctgta ccaggagtat tacggtctgg
     2821 ccggggcttt cctagttatc ggcctgtttt tcggtctggc tgaactttgg gccggacgga
     2881 tgcgttttgt ggggctgagt cataaggagc gacgggagta tgccgatcgc tataagcgcg
     2941 ataataaacg gccagcgcca ttttcggtgc tggcctcgct ggattcgccc gggcggatgg
     3001 tcagggcacg tcgacatgtc tggaactacg cgtactggct gaccggcgcg gccggtctgg
     3061 cccttctggg ggggctggtt gtcgccgtgt ttatcgagag ctggggagaa accgtcctgc
     3121 gtccggacct ctacgcaaac gcagattatt acctgctgca gccggctaac ctgttcggga
     3181 ttgcctggtg cgcgggcggg ctggctgtcg ggattgtgtt ggcgcggctg ctggcgttcc
     3241 tgctgcttga cggtcatttt gcggctgctg acgaggcggt gaacgcgaaa ctgaatcagg
     3301 agagccggcg cagcagccag cggacaggag agatgaccga cgtgcgccac ctgcatttcg
     3361 gggagccggt accggttaat gcgctggccg atttttcctc ggagcaggcc cggcaggagc
     3421 aggcggtgtt tctgggtaag gatgagcagg gcaagccggt gctggttccg cgtgatacct
     3481 ggcgcaagac caacattcag atcctcggcc tgcccgggag cggcaagagc gtgatggcca
     3541 ccaacgcgct cattcgctgc gtacgcgatt tcggggacgc ggtggtgtac ttcgacccca
     3601 aaggggacgc atgggcgccg cacgtcttcc gggcgcactg tccggacttc accctgctgg
     3661 atctgcggcc ggggaaaccg gcgcagctga atctgttccg cgatctcgac cagtacgcgc
     3721 tgaaaaacct gctgattgcc gggcttaacc tgggcgagac cggcgacgtg gcggaccact
     3781 accgcatcag cgagcagaaa gcggcgaagc tgattgcgga gcagtttccg cagggggcaa
     3841 acattcagca ggtgctggcg gcggcgtacg cgctgccgga ggccctgaaa aaggacgtga
     3901 aggggttgat cactaggctg gaaaacgtcg ctgacctgag cgtcctgcag acggacagtg
     3961 gcatcgatgt ggcggggatt atcaacggcg gcggctgcct gtacgttatc ggctcgatgg
     4021 acgacgaggc ggtgatccgt gtgcaaaaaa tgctgtttgc ccgctgcgcg caaatcatca
     4081 ttgcgcggga cgagttccgg gagtggccac acgtcagcgt gatgctcgat gaaattaaat
     4141 atctgctgtc gaagtatgta ctgaacgcac tggggacgct gcgcagccgg gactgcaatc
     4201 tgttgctcgc gcaccagtcg ctgggcgatt tcgggcagtg cgggcaggat ctgcccgctg
     4261 aatttgtgaa aaccacggta ctggataaca cgccgatccg ctggttttac cgggcggcca
     4321 gcctggagtc cgcgcagtgg gcggcggggc agaccgggga aatcagggtg gacgtggagc
     4381 gccgccgtgc cagccgggag gcggggaacg tggagcatat cagcggggac agcttcatcc
     4441 agaaggaggc gcggccgctg tttgacgtga acaccctgca acacctgccg gacgggttcg
     4501 cggtcatgac cgggctgggt gtggcccgga tggcgttcag cagtccgctg cgggttgagc
     4561 gccgggaaat cccgttgcag cgtttcccgg tgctggcgaa aaccgatccc ctggcggagt
     4621 tccggccccc ggccgacggc ggcgggccga aagcggatga tgattttgcg gggatttact
     4681 gatggcgctg gagctgtaca acgtcagcca cgcgaaacga caggcgcgga acgcggagaa
     4741 aacccggctg accctgcgct ggttgcggga agagctgtgt tccacggcgg agctggttgc
     4801 gcggcggctg gggattgcgg cggtgcagcc ggtctaccgc ttcctcgaca gcctggtggc
     4861 gaaagggctg ctggtccgga ccaaatatcc ggtggacggc cgtcaggtca gcgtgtgggg
     4921 gctgacgccg catggcgtgg cgttctcgtt cgacgaggac gaaccgctgg cggatgttat
     4981 tccgtttcag ccgtcaaggg tgtcggcagc acatctgccg caccggctgg ccgtgcaatc
     5041 cctgcgcctt gatatggaag ccagaggggc caccggctgg cgcattctgc accgtctgag
     5101 tcttaaaggc atgaaagtgc cggacgccct ggcggagctg gacggtaaaa cggtggcgtt
     5161 tgaggtggag cgcaccgtca agagccgtcg ccggtatcag gaagtggtgt ccgggtatct
     5221 gttcaaccgc aaagctaacg gcatcgatga aatctggtac atctgcccgg accgggcgac
     5281 gcaggtcagg gtgcagcggg caatcctgtc ggtggatgaa atcgtgaacc cacagaccgg
     5341 cgaggcccgc aaaacggcag agctggatcg tgaacggttg tttgcgtgct ttaaatttat
     5401 gacaacggag tgagggatta tggcgctgta catggtattt attgaagacg cggaggaccg
     5461 gaacggcgag cgctgcatca tgccgaccag cgagcatctg gaagatatgg tggtgctcgc
     5521 ctggcagacc ggggcgtatg ttttctgttt tgtcgaccgg gcccagcatc tggcgatgat
     5581 gaaatccatc gggatgtatg acgagcggct caacagcgac gaaaaagcca cgtacttttt
     5641 cactggtaaa aatccgcaat gggaacggaa caaacccaca ggaatgaagc tgtgtgatta
     5701 cctctatcgc aaggtggagc ggttcgccat cgagaacggt gtgcaggtgg ttgatgccgg
     5761 gaagtgctca ccggagcaga ttaacgcgat gattgacgtg gtgagtgagc ggcacgggga
     5821 aagcgcggtg aacgagaagc tgaaagcgga gctgatgcgg gaatataaca gccgctattt
     5881 taacgtgccg gtacctgaac tgccggagga caaacctgcc cgccggtggt ggccgttcgg
     5941 caaaaaataa atgccagcac cggccatgcc ggtgctgtta ttcctccccg agcttatccc
     6001 gcatcacctg ccagagtgtt tccgcatcct cgtgtagccg ctcgcacatg tcggccgggg
     6061 tatccatatc cagctcattc agtttatcga gcaatagcag cgactgctcc ttaataaatt
     6121 tagccatatt gagggctgtt ttttcctgtt ttgtcatgat tctttccttc cgggcatggt
     6181 gtgcgcctgt caggtatact gtctcaaaaa tagcggggtg agacaatggc gtgggtgacg
     6241 gtgagacagg cgacggaact gacgggtaaa gcccgaagtt ccctgtatcg ggatatggcg
     6301 aaaggccgcg tatcataccg tacggaagct gatggcggcc gggtggtgga taccagcgag
     6361 cttatccggg tgtacggtga gttaagacag gatgagactc acgagcggga cgagttgaga
     6421 ctgtcgggtg agactgaaaa aatggcctcc gacgcgttga tcgcggagat aaaagcactc
     6481 agggaggagg tggccgggct acggcaggaa atgcagtcca tgagactgct ggaacacaaa
     6541 ccggagacag cagagacccc ggccggaaca ccgcgccggt ggtggccgtg gggaaaacgc
     6601 tgacgcgctg tgcttgtcca accggcgacg gccacgcaat gaattgcgtc cccgtcaccg
     6661 gttattagag aacaatatgg ggattctggc gctggccgac cacggccaga acccggactt
     6721 ttctggtctg gtcatcaaca tcatagagga catgctgtcc catcagactg atccggcgaa
     6781 cgtcctcgcc atagcgtgag tccacttcat agagtcgcgg gaagtcggcc agtttgtccg
     6841 ccgcagcgag aacccggtcg gtaacgttct gcgcatccca cagggatgaa ttttccgcga
     6901 tatagtcaaa cagcgtcgtt acatcctcga tggctccctg cttccattcc acgtcatacg
     6961 gcatcgcgca gttcctgata acggccatgc aggcgctggc ggagttgttc cgtggtcata
     7021 cccggacgcg tgtcagcacg ggcggcggtc actttggcgc gaacctgatc ttcatactct
     7081 gcctgggcca gttcttcgtt agccagtcgc tgcaacagcg cagctttgtc cgggccacct
     7141 tccggcagta tgcggggcag gctttcagcc agttcccgaa gaaagttggc gttttcgtag
     7201 tgtgtagtgt tgctcattgc ggagcctccc gggttaatgc ggcaatatga aggaagttta
     7261 gcagggggcg gtctgaaaga atatggtcgt gtcagtcagg ctgatgaagc agaaagtcgg
     7321 taaaaaaggg cttacggcat ccattttacg tcaaaacata tgccatgcag ttgcgtgcat
     7381 aggcatgcat taggataaaa tttatcgggc gcgtttccgg cagttttccg ggggggttgt
     7441 tgcctgtttt atcccgtagc cgccggaaac gccctgagcc cgtctgagcg gtgcgcgtaa
     7501 tgacgcgtta tggtaaatcc acttactgtc tgccttcata gccatcgaga taaacagctg
     7561 aaatggtgtc agccagtagc cttgattttt tcggtgtgag gtctttgctg cggtaatcgg
     7621 tacccgcaaa ttgtgttgtg ccttggagtg agtttaaaaa ttcctgactg tgaaactgct
     7681 gaatgcgttg ctgcacatca ctccgtgatt ttccggtcgc tttatccttt gcgcccatat
     7741 cccagaactg ccggaaaaaa ggcaccatca ttcgtgttgt gtcagctttc tgggtggaaa
     7801 aattgggatc aaaaccgtca tctgaagcat atacgtaatg ccgggtatgc tgttccacgc
     7861 tgccctttgg agcacaggca gtgagagttg ctgtcgctgt tatcatggcg ataagacaca
     7921 gtttgctgcc ggaacgtctc atgagcgtct ccttaccttt aattcttttt tctcattgag
     7981 ttataggggt ctgacgctca gtggaacgaa aactcacgtt aagcaacgtt ttctgcctct
     8041 gacgcctctt ttaatggtct cagatgacct ttggtcacca gttctgccag cgtgaaggaa
     8101 taatggccga gcatattgat atgtccgtgg caaagcgggg agaggcgtgc gatatcttca
     8161 tcattcagtg tttcaccctg cgcccggaga tgatccagag ctgcctgcat ataaatagtg
     8221 ttccataaca cgacggcgtt agtgaccagc cccagagctc ccaactgatc ttcctgaccg
     8281 tcggtatatc gttttcttat ctcacctttt tgaccgtgac agatggctct ggcaactgca
     8341 tgacggcttt ctccccgatt aagctgggtc agaatgcgcc ggcggtaatc ttcatcatca
     8401 atataattaa gcagatacag cgttttgttg atgcgcccca cttcaatgat tgcctgagtc
     8461 agtccggagg gacgttcact tttcagcaat gaacggacca gcactgaggc ctgtactttg
     8521 cccagcttca gggagcctgc ggtccggatc atttcgtccc actgaaggac tatttttcgg
     8581 ggatctgatt gccctctggc aatatcattc agcacgccat agtcggcatc atggtccatt
     8641 cgccagaaaa ccgaagcacc ggcatcagcc aggcgtggag aaaactggta tcccagcagc
     8701 cagaaaaggc caaagacaag atcgctggca cctgccgtat cggtcataat ttcggttgga
     8761 ttcagcccgg tctcctgttc cagaaggcct tccagcacaa agatagagtc cctcagcgtc
     8821 cccggtataa cgatgccatg aaagccggaa tactgatcgg acacaaagtt gtaccaggtg
     8881 atccctctgt tattaccaaa gtatttgcgg ttcggtccgg cattgattgt tctgactggc
     8941 gtaacaaagc gcattccatc tgcagatgcc acttctcctc caccccatat ctgtgccagt
     9001 ggcagcgttg cctgaaaatc aaccagtctg gcattagcgc tggtgatagt ttcagcccgc
     9061 agatagttcg cttttgtcca gttcagccgg tgtcgggtca gtgcaggaac atttgatctg
     9121 atcagtggtt ccagaccgat attgcaggct tcagccatca gcacggcgct gatgctgacg
     9181 ggcagatcat caactctggc actggcttca ctggcatgga aaaactcatc agcaaatccg
     9241 gtatgggcgt taatttcgag cagcaactcc gttaaatcca ccggagggag cagatcactg
     9301 atcattttgc tcagtcgttt cagactgtcc ggctcatcaa gactggcgag gggagaaatt
     9361 gtcaaccggg gcttcgggcc agaaacatcg agttcgacag cctcattttc gccaagacgt
     9421 gcagcaacct gtctgtaacg actatcaagc tgatggccca gagattttat tgcttcctgc
     9481 gggtctgtcg ggtgccccaa agaacgataa accttaatcc gatttgcctg ccagtcagca
     9541 ccctgtagta atcttgcacg aggatctccc caccggttac tgccggtaac gtagacatcc
     9601 ctccgtctca gactatcctg cagtttactg agaaagcaga gcgtgtatcc ccttcgggtg
     9661 atatgttttt ccttgttaat caccagccgt ttccatgact gactgatgat ttccgttggt
     9721 gcgtcgtcaa aaaactgccg ccgtgagctg aactcccggc tgaggtagtc acaggcattc
     9781 agagtggtaa ccccggcagg tgcggatgaa aatttaacgg tattcagcag atggggcagg
     9841 aaacgacgaa cgcgcccgta ctgctccacc atttcgtcat gaaaattatc gtctgagggc
     9901 cgggcaattt cacggacaag cgtgatgatt tcagccagct tttgcctagg gatgtagctg
     9961 aacacctcag cacgaatcga ttcgtccggt gtttcttctt tcagcaagta cgaacatgcg
    10021 ctggcgagcg ccaatgcaga tttatccaga tccttcagcg agcggagccg ttttttctgc
    10081 ccaatctttc tggcgtcacg gatgataacg gccagcatgg cgtccagaac gtccagtgca
    10141 tcatccagcg ccagcgtttc ccatgcaagg acaaaggcaa ccagaaccgc catccttttc
    10201 tgcggtgaca tcctggcaat attgaacacc gaagtcatac cagcataacg tgcgagattt
    10261 ttcaggcgca cagccgggag tgtactcagg ttttcagcat gcaggccaaa atcgttcaga
    10321 gttttccagc gttcaattgc ttcattaaac gccggaccac tgatggtcac agggcctttt
    10381 ttcagtgatt ccagtaaaga caggcggctg caatcagttg gccccagcag catctccagc
    10441 tgtgaacgct gttcggctga cggtatcagt gccagtttgt tccacaggcg caacgtcgcc
    10501 ttttccctta cctctgaaat caaccgggtc agcgtggtgg ctccggggag aataatacga
    10561 tgttgcataa gccaccctgt cgccaggtcg aaaagcaggc caggacgttc gttgcttatc
    10621 cagctccggg tatataaaag acgggtaagg cgaaatgtcc agggccaggc aaattcacga
    10681 tactgatagt gctgacgtat cagcgctgca tgctcacggc gggtattttc cctctgaccg
    10741 tattctgcaa gaacggtgat atcacgaatc ccgagctgtc tggcggtaaa atgccggacg
    10801 ccggaaggaa tatgattcat gtcagtaaga aaagtgccca gaaaacgcac acacccgatt
    10861 tgcagggcaa taccaagtcg attgtgatca ccccggcttt tcccgataaa ttctttatcc
    10921 gcttcatcaa gatgaaaata acgcgccagc tgaagttcat cgggttcgcc agtgaacctg
    10981 ccataactct caacctgctc agtggtcaaa aaatcaacgg gcatatcggc ctccctgcct
    11041 gacggctttt ttaacacaac tgcaaccgtt cgaaatatta taaattatca gacatagtaa
    11101 aacggcttcg tttgagtgtc cattaaatcg tcattttggc ataatagaca catcgtgtct
    11161 gatattcgat ttaaggtaca tttttatgcg aatttttggt tatgcgcggg tctcaaccag
    11221 ccagcagtcc ctcgatattc agatcagagc gctcaaagat gcaggggtaa aagctaaccg
    11281 catctttacc gacaaggcat ccggcagttc aacagatcgg gaagggctgg atttgctgag
    11341 gatgaaggtg gaggaaggtg atgtcattct ggtgaagaag ctcgaccgtc ttggccgcga
    11401 caccgccgac atgatccaac tgataaaaga gtttgatgct cagggtgtag cggttcggtt
    11461 tattgacgac gggatcagta ccgacggtga tatggggcaa atggtggtca ccatcctgtc
    11521 ggctgtggca caggctgaac gccggaggat cctagagcgc acgaatgagg gccgacagga
    11581 agcaaagctg aaaggaatca aatttggccg caggcgtacc gtggacagga acgtcgtgct
    11641 gacgcttcat cagaagggca ctggtgcaac ggaaattgct catcagctca gtattgcccg
    11701 ctccacggtt tataaaattc ttgaagacga aagggcctcg tgatacgcct atttttatag
    11761 gttaatgtca tgataataat ggtttcttag acgtcaggtg gcacttttcg gggaaaagtg
    11821 cgcggaaccc ctatttgttt atttttctaa atacattcaa atatgtatcc gctcatgaga
    11881 caataaccct gataaatgct tcaataatat tgaaaaagga agagtatgag tattcaacat
    11941 ttccaaacaa agttaggcat cacaaagtac agcatcgtga ccaacagcaa cgattccgtc
    12001 acactgcgcc tcatgactga gcatgacctt gcgatgctct atgagtggct aaatcgatct
    12061 catatcgtcg agtggtgggg cggagaagaa gcacgcccga cacttgctga cgtacaggaa
    12121 cagtacttgc caagcgtttt agcgcaagag tccgtcactc catacattgc aatgctgaat
    12181 ggagagccga ttgggtatgc ccagtcgtac gttgctcttg gaagcgggga cggatggtgg
    12241 gaagaagaaa ccgatccagg agtacgcgga atagaccagt tactggcgaa tgcatcacaa
    12301 ctgggcaaag gcttgggaac caagctggtt cgagctctgg ttgagttgct gttcaatgat
    12361 cccgaggtca ccaagatcca aacggacccg tcgccgagca acttgcgagc gatccgatgc
    12421 tacgagaaag cggggtttga gaggcaaggt accgtaacca ccccagatgg tccagccgtg
    12481 tacatggttc aaacacgcca ggcattcgag cgaacacgca gtgttgccta acccttccat
    12541 cgagggggac gtccaagggc tggcgccctt ggccgcccct catgtcaaac gttaaacatc
    12601 atgagggaag cggtgatcgc cgaagtatcg actcaactat cagaggtagt tggcgtcatc
    12661 gagcgccatc tcgaaccgac gttgctggcc gtacatttgt acggctccgc agtggatggc
    12721 ggcctgaagc cacacagtga tattgatttg ctggttacgg tgaccgtaag gcttgatgaa
    12781 acaacgcggc gagctttgat caacgacctt ttggaaacgg cactgttgca aatagtcggt
    12841 ggtgataaac ttatcatccc cttttgctga tggagctgca catgaaccca ttcaaaggcc
    12901 ggcattttca gcgtgacatc attctgtggg ccgtacgctg gtactgcaaa tacggcatca
    12961 gttaccgtga gctgcaggag atgctggctg aacgcggagt gaatgtcgat cactccacga
    13021 tttaccgctg ggttcagcgt tatgcgcctg aaatggaaaa acggctgcgc tggtactggc
    13081 gtaacccttc cgatctttgc ccgtggcaca tggatgaaac ctacgtgaag gtcaatggcc
    13141 gctgggcgta tctgtaccgg gccgtcgaca gccggggccg cactgtcgat ttttatctct
    13201 cctcccgtcg taacagcaaa gctgcatacc ggtttctggg taaaatcctc aacaacgtga
    13261 agaagtggca gatcccgcga ttcatcaaca cggataaagc gcccgcctat ggtcgcgcgc
    13321 ttgctctgct caaacgcgaa ggccggtgcc cgtctgacgt tgaacaccga cagattaagt
    13381 accggaacaa cgtgattgaa tgcgatcatg gcaaactgaa acggataatc ggcgccacgc
    13441 tgggatttaa atccatgaag acggcttacg ccaccatcaa aggtattgag gtgatgcgtg
    13501 cactacgcaa aggccaggcc tcagcatttt attatggtga tcccctgggc gaaatgcgcc
    13561 tggtaagcag agtttttgaa atgtaaggcc tttgaataag acaaaaggct gcctcatcgc
    13621 taactttgca acagtgccct gataaatctg gagccggtga gcgtgggtct cgcggtatca
    13681 ttgcagcact ggggccagat ggtaagccct cccgtatcgt agttatctac acgacgggga
    13741 gtcaggcaac tatggatgaa cgaaatagac agatcgctga gataggtgcc tcactgatta
    13801 agcattggta actgtcagac caagtttact catatatact ttagattgat ttaaaacttc
    13861 atttttaatt taaaaggatc taggtgaaga tcctttttga taatctcatg accaaaatcc
    13921 cttaacgtga gttttcgttc cactgagcgt cagacccctt atatatccgc aggctatctt
    13981 atcatcagtt tctgaccgtg ttcagtgacc gaacaacccg aaccagaccc ccgtttcttt
    14041 tcctgtcccg gagggggctt tctggtatct catataatga tttcagtaaa acatactgag
    14101 gccggagaac ggcgccgttt gtgctggttt ttgttgcatc tggaggggat tgcgcatggt
    14161 gtgagtggct gtttttttga tcattttcac aaaaacgcaa atttacagac ttgacatgaa
    14221 aaacaaggca gcgtaatttt tatactgtat ataaaaccag tggttatatg tacagtattt
    14281 tattttagtt tattgtttta aaagtcaaag aggaaaagta tatgagtggc ggagacggac
    14341 gaggtccggg taattcaggt ctgggacaca atggtggtca ggccagtggg aatgtgaacg
    14401 gtacatcagg taaaggtggc ccttcatcag gtggtggtac ggatccaaac agcgggccgg
    14461 gctggggtac gacgcataca cctaacgggg atattcataa ctataacccg ggggagtttg
    14521 gtaacggcgg gagtaaaccc ggtggtaatg gcggtaacag cggcaatcat agcgggagct
    14581 ctggtggcgg acagtcttcg gccaccgcga tggccttcgg tctgcctgcc ttggccactc
    14641 cgggggctga aggactggct ttatccgttt ccggcgatgc gttgtcggcc gctgttgctg
    14701 atgtgctggc tgccctgaaa ggtccgttta agtttggtct gtgggggatt gcgatttacg
    14761 gagtgctgcc ttctgagata gcaaaagatg atccgaaaat gatgtcaaaa atcgtgacgt
    14821 cattgccggc agacacggta acggagacgc cggtcagctc cctgccgctg gaccaggcga
    14881 cggtcagcgt cactaaacgt gtggcggata ttgtgaagga cgagcggcag catattgcgg
    14941 ttgtcaccgg ccggccaatg agtgttcctg tggtggatgc gaaaccgaca aaacgtccgg
    15001 gggtattcag tgtgtcgatt ccgggtctcc cgtctctgca ggtgagcgta cctaaaggtg
    15061 ttccggccgc gaaagccccg ccaaaaggca ttattgctga aaaaggtgat tcacgtccgg
    15121 ctggttttac ggccggtggt aactcccgtg aagccgttat tcgtttcccg aaagagagcg
    15181 gacagaaacc ggtctatgtg tcggtgacgg atgttcttac tccggcacag gtaaaacagc
    15241 gtctggagga agaaaagcgt cgccagcagg c
//
