LOCUS       NZ_CP020546.1          16257 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CP020546.1 Escherichia coli strain ZJ3920 plasmid pZJ3920-1,
            complete sequence.
ACCESSION   NZ_CP020546
VERSION     NZ_CP020546.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-06-07 19:54:51
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16257
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16257
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[532:2257]"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      533..2257
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
     cand_cluster    1..16257
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="IucA_IucC"
                     /kind="single"
                     /product="NI-siderophore"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..16257
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NI-siderophore"
                     /region_number="1"
                     /rules="IucA_IucC"
                     /tool="antismash"
     CDS             complement(2..532)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1203:putative siderophore biosynthesis protein (Score:
                     95; E-value: 1.1e-28)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1"
                     /transl_table=11
                     /translation="MSGANIVHSGYGLRCEKLDKPLNLGWGLDNSAVLHWPGELPTGWL
                     CDALDQIFIAAPQLSAVVLPWSEWYEEPQALTLFGQVQSDIIHRSAFWQLPLWLSSPAN
                     RASGEMVFDAEREIYFPQRPPRPQGEVYRRYDPRIRRMLSFRIADPVSDAERFTRWMND
                     PRVEYFWEQSGSLE"
     CDS             complement(533..2257)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2"
                     /sec_met_domain="IucA_IucC (E-value: 1.7e-62, bitscore:
                     204.3, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MILPSEKSATDVAAQCFLNALIRETKDWQLAEYPPDELIIPLDEQ
                     KSLHFRVAYFSPTQHHRFAFPAHLVTASGSYPVDFTTLSRLIIDKLRHQLFLPVPLCET
                     FHQRVLESYAHTQQTIDARHDWAILREKALNFGEAEQALLTGHAFHPAPKSHEPFNRQE
                     AERYLPDMAPHFPLRWFSVDKTQIAGESLHLNLQQRLTRFAAENAPQLLNELSDNQWLF
                     PLHPWQGEYLLQQVWCQALFAKGLIRDLGEAGTSWLPTTSSRSLYCATSRDMIKFSLSV
                     RLTNSVRTLSVKEVERGMRLARLAQTDGWQMLQARFPTFRVMQEDGWAGLRDLNGNIMQ
                     ESLFSLRENLLLEQPQSQTNVLVSLTQAAPDGGDSLLVSAVKRLSDRLGITVQQAAHAW
                     VDAYCQQVLKPLFTAEADYGLVLLAHQQNILVQMLGDLPVGFIYRDCQGSAFMPHATEW
                     LDTIDEAQAENIFTREQLLRYFPYYLLVNSTFAVTAALGAAGLDSEANLMARVRTLLAE
                     VRDQVTHKTCLNYVLESPYWNVKGNFFCYLNDHNENTIVDPSVIYFDFANPLQAQEV"
     CDS             2393..3586
                     /locus_tag="ctg1_3"
                     /transl_table=11
                     /translation="MSSKIEDTPQKTLSCWPLAFSAGLLGIGQNGLLVVLPVLVIQTNL
                     SLSVWAALLMLGSMLFLPSSPWWGKQISLTGSKTVVLWALGGYGVSFTLLGLGSVLMAT
                     GAVTTAVGLGILIIARIVYGLTVSAMVPACQVWALQRAGEGNRMAALATISSGLSCGRL
                     FGPLCAAAMLVIHPLAPVWMLMAAPVWAVVMLLRLPGTPPQPTPERKSVSLKRDCLPYL
                     LCAMLLAAAMSMMQLGLSPALTRQFDTDTTTISQQVAWLLGLSAIAALIAQFVVLRPQR
                     LTPVALLLSAGVLMSSGLAIMLTEQLWLFYLGCAVLSFGAALATPAYQLLLNDKLADGA
                     GAGWLAASHTLGYGLCALLVPLASKTGVSIALIVTALFAAVLFTIVSACIWHYRTIK"
     CDS             complement(3966..4346)
                     /locus_tag="ctg1_4"
                     /transl_table=11
                     /translation="MIKSLFAVIIGGSVGCTLRWLLSTRFNSLFPNLPPGTLVVNLLAG
                     LIIGTALAYFLRQPHLDPFWKLMITTGLCGGLSTFSTFSVEVFALLQAGNYIWALTSVL
                     VHVIGSLIMTALGFFIITILFA"
     CDS             complement(4418..4633)
                     /locus_tag="ctg1_5"
                     /transl_table=11
                     /translation="MKAHVFVISMLTGIVVTYAVLLLGCLFIDKTLPTVDVVILSLVVG
                     ASAQQLSRVLMSINRTFPYLACSQRI"
     CDS             complement(4687..5121)
                     /locus_tag="ctg1_6"
                     /transl_table=11
                     /translation="MIFLPLTVAEDDWAGWKILHGALGEQIELVGDDLFVTNVKYIQRG
                     IDENLANSALIKLNQIGSLSETFDAVQLCHDNNWGTFISHRSGETVDSFIADMTVAMRA
                     GHLKTGAPCRGERIEKYNQLMRIEDELGSSAQFAGKSAFK"
     CDS             complement(5589..6446)
                     /gene_functions="other (smcogs) SMCOG1245:ABC transporter
                     protein, integral membrane (Score: 293.7; E-value:
                     2.1e-89)"
                     /gene_kind="other"
                     /locus_tag="ctg1_7"
                     /transl_table=11
                     /translation="MMALLLEPLQFTFMSHALLISLVVSIPCALLSVFLVLKSWALMGD
                     AMSHAVFPGIVLAWILGLPLATGAFVAGVFCAVATGYLKDNSRIKQDTVMGIVFSGMFA
                     AGLILYIAVKPDVHLDHILFGDMLGITIGDIIQTVIIAGLVTLVISVKWRDFLLFSFDY
                     QQAQASGLHTRWLHYGLLCMVSLTIVATLKAVGIILSISLLIAPGAIAVLLTQRFHIAL
                     LLATGISILVSMTGVWLSFFIDSAPAPTIVVLFAVMFIMTFTVTSINARTKENAEPRDL
                     LSSD"
     CDS             complement(6443..7300)
                     /gene_functions="other (smcogs) SMCOG1245:ABC transporter
                     protein, integral membrane (Score: 302; E-value: 6.2e-92)"
                     /gene_kind="other"
                     /locus_tag="ctg1_8"
                     /transl_table=11
                     /translation="MNALLEPFSYEYMLNAMWVSAMVGGLCAFLSCYLMLKGWSLIGDA
                     LSHSIVPGVAGAYMLGLPFSLGAFFSGGLAAGSMLFLNQLTRLKEDAIIGLIFSSFFGL
                     GLFMVSLNPTSVNIQTIVLGNILAIDPADILQLTIIGILSIIVLFFKWKDLMVTFFDEN
                     HARAIGLHPGRLKILFFTLLSVSTVAALQTVGAFLVICLVVTPGATAWLLTDRFPRLLM
                     IAVTIGSVTSFLGAWVSYFLDGATGGIIVVAQTLLFLLAFVFAPTHGLLANRRRAHKAL
                     EDRS"
     CDS             complement(7297..8124)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 180.8; E-value:
                     5.5e-55)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_9"
                     /transl_table=11
                     /translation="MMQSAGIVVNDVTVTWRNGHTALRDASFTVPGGSIAALVGVNGSG
                     KSTLFKAIMGFVRLTSGKISVLGIPTRQALQKNLVAYVPQSEEVDWSFPVLVEDVVMMG
                     RYGHMGMLRIAKKRDRQIVTDALERVDMVDFRHRQIGELSGGQKKRVFLARAIAQQGDV
                     ILLDEPFTGVDVKTEAKIISLLRELRAEGKTMLVSTHNLGSVTTFCDYTVMVKGTVLAS
                     GPTDTTFTAENLELAFSGVLRHVTLNGSEESIITDDERPFVAHRPSAVQREER"
     CDS             complement(8124..9038)
                     /gene_functions="transport (smcogs) SMCOG1252:cation ABC
                     transporter, periplasmic (Score: 310.5; E-value: 1.8e-94)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_10"
                     /transl_table=11
                     /translation="MLSIKKVTMLLGCLVLTCSIAFQASAAEKFKVITTFTIIADMAKN
                     VAGDAAEVSSITKPGAEIHEYQPTPGDIKRAQGAQLILANGMNLELWFQRFYQHLNGVP
                     EVIVSSGVTPVGITEGPYEGKPNPHAWMSPDNALIYVDNIRDAFIKYDPANAQTYQRNA
                     DTYKAKITQTLAPLRKQIAELPENQRWMVTSEGAFSYLARDLGLKELYLWPINADQQGT
                     PQQVRKVVDIVKKNHIPAVFSESTISDKPARQVARETGAHYGGVLYVDSLSTENGPVPT
                     YIDLLKVTTSTLVQGIKAGKREK"
     CDS             9394..9669
                     /locus_tag="ctg1_11"
                     /transl_table=11
                     /translation="MASVSISCPSCSATDGVVRNGKSTAGHQRYLCSHCRKTWQLQFTY
                     TASQPGTHQKIIDMAMNGVGCRVTARIMGVGLNTILRHLKNSGRSR"
     CDS             9714..10091
                     /locus_tag="ctg1_12"
                     /transl_table=11
                     /translation="MDEQWGYVGAKSRQRWLFYAYDSLRKTVVAHVFGERTMATLGRLM
                     SLLSPFDVVIWMTDGWPLYESRLKGKLHVISKRYTQRIERHNLNLRQHLARLGRKSLSF
                     SKSVELHDKVIGHYLNIKHYQ"
     CDS             complement(10271..10522)
                     /locus_tag="ctg1_13"
                     /transl_table=11
                     /translation="MKAGVMLADFTPSGIAQPGLFDEIQPRKNSEKLMKTLDELNQSGK
                     GKVWFAGRGTAPEWQMKREMLSQCYTTKWRDIPLARLG"
     CDS             complement(10918..11274)
                     /locus_tag="ctg1_14"
                     /transl_table=11
                     /translation="MLSREDFYMIKQMRQQGAYIVDIAAQIGCSERTVRRYLKYPEPPA
                     RKTRHKMVKLKPFMDYIDMRLAENVWNSEVIFAEIKAMGYTGGRSMLRYYIQPKRKMRP
                     SKRTRRELPVKRET"
     CDS             11315..11611
                     /locus_tag="ctg1_15"
                     /transl_table=11
                     /translation="MLGGADNPNGELPSYITGADTCSLYTQSLALKHTYEVYFGYDRTL
                     RKYGRFRQKLPVKTDIRKNSARRRPVTGRSPRTGEEAQCICSYREQVRPEALS"
     CDS             12020..12997
                     /locus_tag="ctg1_16"
                     /transl_table=11
                     /translation="MDKSSGELVTLTPNNNNTVQPVALMRLGVFVPTLKSLKNSKKNTL
                     SRTDATEELTRLSLARAEGFDKVEITGPRLDMDNDFKTWVGIIHSFARHNVIGDKVELP
                     FVEFAKLCGIPSSQSSRRLRERISPSLKRIAGTVISFSRTDEKHTREYITHLVQSAYYD
                     TERDIVQLQADPRLFELYQFDRKVLLQLKAINALKRRESAQALYTFIESLPRDPAPISL
                     ARLRARLNLKSPVFSQNQTVRRAMEQLREIGYLDYTEIQRGRTKFFCIHYRRPRLKAPN
                     DESKENPLQPSPAEKVSPEMAEKLALLEKLGITLDDLEKLFKSR"
     CDS             complement(13073..13192)
                     /locus_tag="ctg1_17"
                     /transl_table=11
                     /translation="MFYEGSNASASGYGITYVRDRQMAAQLQTALQETEYKLQ"
     CDS             complement(13282..14022)
                     /gene_functions="other (smcogs) SMCOG1077:phage integrase
                     family protein (Score: 88.1; E-value: 1.5e-26)"
                     /gene_kind="other"
                     /locus_tag="ctg1_18"
                     /transl_table=11
                     /translation="MNNVIPLQNSPERVSLLPIAPGVDFATALSLRRMATSTGATPAYL
                     LAPEVSALLFYMPDQRHHMLFATLWNTGMRIGEARMLTPESFDLNGVRPFVRILSEKVR
                     ARRGRPPKDEVRLVPLTDISYVRQMESWMITTRPRRREPLWAVTDETMRNWLKQAVRRA
                     EADGVHFSIPVTPHTFRHSYIMHMLYHRQPRKVIQALAGHRDPRSMEVYTRVFALDMAA
                     TLAVPFTGDGRDAAEILRTLPPLR"
     CDS             complement(14705..15607)
                     /locus_tag="ctg1_19"
                     /transl_table=11
                     /translation="MSIKNIKRIITAWKPSTFETYKKTFEKYGGSVNMHPDVVSYFMIH
                     HDWKFDFFHYEKDGDIKGSYFLCNGKQIGIMARRSYPLSSDEVLIPFSPHARCFFPDKT
                     NKLSIINKQNIINATWKIARKKQNCIIKESFSPKFEKTRRNEIQRFIRNGGEIKCISKL
                     SDKEISSSYISLFHSRFGGTLPCYEYDNLLMFISHLRELMFGHVLFWDNKPCAIDIVLK
                     SESSCNVYYDVPNGAVLNDENCMKLSPGSVLMWLNIDKARRYCQDNNKKMIYSIGAFRP
                     EWKYKLLWSVPCKVGKCLC"
ORIGIN
        1 cctccagtga gccactttgc tcccagaaat actcaacgcg cggatcgttc atccagcgag
       61 tgaaacgttc tgcatcagaa acgggatcgg caatgcggaa actcagcatc ctgcgaatgc
      121 gtggatcgta acgacgataa acttcaccct gcggacgggg ggggcgctgc gggaaataaa
      181 tctcacgctc tgcatcaaaa accatttcac cggaggcccg gtttgccgga gaactcagcc
      241 ataacggtaa ctgccagaaa gcggaacgat ggataatgtc gctttgtacc tgtccgaaaa
      301 gcgtcagcgc ctgtggctcc tcataccatt cggaccaggg aagaaccact gctgaaagtt
      361 gtggtgcggc gataaatatc tgatccagcg cgtcgcacag ccaccctgtt ggcagctccc
      421 cgggccagtg caacaccgcg ctattgtcca gcccccagcc aagattcaga ggcttgtcga
      481 gtttttcaca gcgcagtcca tatccgctgt gaacaatgtt tgccccagac attcagacct
      541 cctgagcctg cagcgggtta gcgaaatcaa aatagatcac cgaagggtca acgatggtgt
      601 tctcgttatg atcgttcaga taacagaaaa agttaccttt tacgttccag tacggacttt
      661 ccagaacata gttgagacag gttttatgag tcacctggtc acgcacttca gccagcaatg
      721 ttcgtacacg agccatcaga ttcgcttcgc tgtccagccc ggcagcaccc agcgcagcag
      781 ttacggcaaa agtggagtta accagcaggt aataagggaa atagcgcagc aactgctcac
      841 gggtgaaaat attttccgcc tgcgcctcgt caatggtatc gagccactct gtcgcgtgag
      901 gcataaacgc gctgccctgg cagtcacggt aaataaatcc gaccggcaga tccccaagca
      961 tctgcacaag aatattttgc tgatgcgcca gcagcaccag gccgtaatcc gcttcagccg
     1021 taaacagagg cttcagcacc tgctgacagt aagcatcgac ccatgcgtgg gcggcctgtt
     1081 gcacagtgat accgaggcga tcgctcaggc gttttaccgc cgaaaccagc agcgaatcac
     1141 cgccatccgg tgcggcctga gtcagggaaa ccagaacgtt ggtctggctt tgcggctgct
     1201 ccagcagcag gttttcacgc agggaaaaca aactttcctg catgatgttg ccgttaagat
     1261 cgcgcagccc ggcccagccg tcctcctgca ttacccggaa agtagggaag cgggcctgta
     1321 gcatctgcca gccgtcggtt tgcgccagac gtgccaggcg cattcctcgc tccacctctt
     1381 tcacagacag agtacggacg gagttggtca gccgaacgct cagggagaac ttgatcatat
     1441 cgcggctggt agcacagtag agggagcggg aagaggtggt cggcagccac gacgtgccgg
     1501 cctcgcctaa gtctctgata agtcctttag caaaaagtgc ctggcaccac acttgctgca
     1561 aaagatattc tccctgccac gggtgcagcg ggaacagcca ttgattgtca cttaattcgt
     1621 tgagtaactg gggcgcattt tctgcggcaa atcgcgtcaa ccgctgttga aggttaagat
     1681 gcagactttc accagcgatt tgcgttttat ccaccgaaaa ccaccgcagc gggaagtgag
     1741 gtgccatgtc aggcaggtat cgttcagctt cctggcggtt aaacggttca tgagacttag
     1801 gtgcagggtg gaaagcgtgt cctgtcagca gtgcctgctc agcctcgcca aaattcaacg
     1861 ctttttcacg caggatggcc cagtcatggc gggcatcaat tgtctgttgc gtatgggcgt
     1921 agctttccag cacgcgttgg tggaaagttt cgcagagggg aactggcaga aaaagttgat
     1981 gccggagctt atcaataata agccgggaga gagtggtaaa gtcgacagga taactgcctg
     2041 atgccgtgac cagatgagca ggaaatgcaa agcggtgatg ctgggttggg gagaaataag
     2101 ccactctgaa atggagcgac ttctgttcgt ccagcgggat aatcaattcg tctggcgggt
     2161 attccgccag ttgccagtct ttggtttcac gaatcaaggc attcaggaag cactgcgcag
     2221 ccacatctgt ggcggatttt tcagagggca ggatcataat caaacagctc ctacacagta
     2281 aaataataac aattatgtca ataatgattc tcattatcaa tgagaaatgt tattgtcaga
     2341 aaaattaatt ttacaaataa acacaattaa tacatggtgt tgaaacatta caatgtcatc
     2401 taagatcgaa gatacgcccc aaaaaaccct gtcctgctgg ccactggcgt tcagtgccgg
     2461 tcttctcggt atcggacaga acggtctgct ggttgtactc cctgttctgg tcatacagac
     2521 aaatctgagt ctgtctgtat gggctgccct gctgatgctg ggctcaatgc tgtttctgcc
     2581 atcttcccca tggtggggaa agcaaatttc ccttactggc agtaagactg tggtgctgtg
     2641 ggctctggga ggatatggcg taagctttac cctgcttggg ctgggaagcg tgctgatggc
     2701 taccggtgcc gtaacaacag cggtggggtt gggaatatta atcatcgccc ggatcgtcta
     2761 cggtctgacc gtgtcagcaa tggtgccagc ctgtcaggtc tgggcattgc agagagcggg
     2821 agaagggaat cgcatggccg ctctggcaac catcagctcc ggcctgagct gcggcaggct
     2881 attcgggccg ctgtgcgcgg cggcaatgtt ggtcattcac cctctggcgc cagtgtggat
     2941 gctgatggca gctccggtgt gggctgtggt gatgcttctg cggttgcccg gcacaccacc
     3001 acagcccaca ccggagcgca agagcgtcag cctgaagcgg gattgcctgc cttatctgct
     3061 ttgcgcaatg ttactggctg cggcaatgag catgatgcag cttggacttt cgccagccct
     3121 tactcgccag ttcgatactg ataccaccac tattagccaa caggtggcgt ggttgttggg
     3181 gctgtccgca atagctgcgc ttatcgcgca gttcgtggta ctccgtccac agcgcctgac
     3241 tccagtggct ctgctcctga gtgccggggt gttgatgagt agtggtctgg ctatcatgct
     3301 cactgaacag ctatggttgt tttacctggg ctgtgcagtg ctgtcatttg gggccgctct
     3361 ggcaacaccc gcttatcaac ttttactgaa tgataagctg gccgacggcg caggcgcggg
     3421 ctggcttgcg gccagtcaca cacttggcta tgggctgtgc gcattgttgg tgccactggc
     3481 gtcgaaaaca ggtgtctcaa tcgcgctgat tgtgacggca ttatttgccg ctgtattatt
     3541 taccatagtg tctgcatgta tttggcatta ccgtacaatc aagtaaggct atgatgttgt
     3601 actcacagcc ggcataacgt cctgtgcaat ttcgctgtcg aaaccgcctg tgctgaccgc
     3661 ccagtgcact cacctgaagc acatcgcagc atgccaccag gatgccagat cgtcttctga
     3721 aatgggtgga tacattggca acgttaaccg caacaatttt tcagagagaa ttttgggggg
     3781 tgagggccag tgatgtaaaa aatacgccaa gaggttaatt cattgtttat actgatatgt
     3841 caggtaatgc gtttgcagtc attacagtcg tcatggagac tgtaatgact gcaaacgcat
     3901 accatggagc gaaattctat cctaagcgtc acattagttg ataaacctgt aacgttaatg
     3961 aattctcatg cgaaaagtat ggttatgata aaaaagccta aagctgtcat gatgagggag
     4021 ccaatgacgt gaacaagtac agacgtcaaa gcccatatat aatttcccgc ctggagtaat
     4081 gcgaatactt caacagaaaa tgtagagaaa gtactcagac ctccacaaag tcccgttgtt
     4141 atcattaatt tccaaaaagg atcaaggtgt ggttgtcgta aaaagtacgc caacgcagta
     4201 ccaataatta acccggcaag gaggttcacc accagtgtac ctggaggtag atttggaaaa
     4261 agactgttaa agcgtgtgga cagtaaccag cgcagagtac atccaacaga accgccgata
     4321 atgacggcaa aaagtgattt aatcatgtac ccctcataaa ataatttttt atcgtaacaa
     4381 tatcagaata tgttctcatt tgactgatat tgttaattta tatcctttga ctacatgcaa
     4441 gataagggaa ggttctattt attgacatta ataccctcga caattgctga gcagaagccc
     4501 ccacgacaag tgacagaatg acaacatcta cagtggggag cgttttatcg atgaacaagc
     4561 aaccaagaag taacacggca taggtgacga caatgccagt aagcatagaa ataacaaaaa
     4621 cgtgagcttt catcattcct ccagaataac cccgacgtgt aagcctgggg gattggcaca
     4681 ataatgtcat ttaaaggcag actttccggc aaattgcgcc gatgaaccca gttcatcctc
     4741 aattctcata agctggttat atttttcaat acgctcaccc cggcatggag ctcccgtttt
     4801 gagatgacct gcgcgcattg caactgtcat atcggcgata aagctgtcca ctgtctcacc
     4861 actgcggtgt gagataaagg tgccccagtt gttgtcatgg caaagttgta ccgcatcaaa
     4921 ggtttcactc agggaaccaa tctggttgag tttaatcaat gctgaattgg caaggttttc
     4981 gtcaatgccg cgctgaatat actttacgtt ggtcacaaac agatcgtcgc caaccaattc
     5041 tatctgctct cccaatgcac catgcaggat tttccatcca gcccagtcat cttcagctac
     5101 cgttaagggc aggaagatca actaggtgct ctggggctgg tgaccaatgc ggttgtgctg
     5161 tgaaacacac tttacatgca ggaggcgttg tcacatcttc gcaaatcggg agaaactcct
     5221 gaggagtagc atccggcaag attatcgctg ctgatacata gccatataaa tatgctgggg
     5281 cattatacgt cttcgttacc ggaagatatt cttaagggtg agttaagatc attaaacttc
     5341 aatacaaaca attaattaaa ctcttagcgt ggttttttac atcactggcc ctcgcccccc
     5401 aattttctct atgttttgcc actacttccc tcattttact gcgctgtttg ctacccctga
     5461 gaatcgacat tacttgctat ccagtccgca gcaactctct ggcaacaaaa cttatcagaa
     5521 tcataagtct gtgcattatt cgttcaagcg catcgccaat aagcggatgt tgctggccga
     5581 gtgttctgct aatcggatga taacaaatcc cgtggttcgg cattttcctt tgtgcgtgcg
     5641 ttgatgctgg taacggtaaa cgtcatgatg aacatgaccg cgaataagac aacaattgtc
     5701 ggagctggcg cgctgtcgat aaaaaaggac agccagacac cagtcattga gaccaatatc
     5761 gatatgccag tcgccagcag gagcgcaata tgaaagcgtt gtgtcaggag taccgcaatg
     5821 gcaccaggcg caatgagaag agaaatagag agaatgatac ctaccgcttt cagcgtcgcc
     5881 acaatggtca gggagaccat gcacagcagc ccataatgca gccatctcgt atgcaaaccg
     5941 cttgcctgcg cctgttgata atcaaagctg aacagcaaaa aatcccgcca ttttacgcta
     6001 ataacaagtg taaccagtcc ggcaataatc accgtctgga ttatatcgcc gatggttatc
     6061 ccgagcatgt cgccgaaaag aatatgatca agatgtacgt ctggtttgac tgcaatatac
     6121 aagatcagac ctgcggcaaa catgccagaa aaaacaatcc ccatcactgt atcttgcttg
     6181 attcggctgt tgtctttcag gtatcccgtc gccaccgcac agaatactcc ggcgacgaat
     6241 gcccctgtag ccagaggtaa ccccagaatc caggcaagca cgatgccagg aaaaaccgca
     6301 tgactcatcg cgtcacccat cagtgcccaa cttttcagga ccagaaagac cgacagcagc
     6361 gcacagggta tggaaactac cagtgaaatc agcagtgcgt gactcataaa ggtgaactgc
     6421 agtggctcca gtaataatgc catcatgagc gatcctccag cgctttatgc gcacgccgac
     6481 gatttgccaa aagcccatgg gtgggcgcaa agacaaatgc taaaagaaac agcagtgtct
     6541 gcgccaccac gatgattcca cctgtcgcgc cgtccagaaa gtaactgacc cacgcgccga
     6601 ggaaactggt cacactgcca atagttacag caatcatgag caggcgggga aaacgatcgg
     6661 ttaacaacca tgctgttgca ccgggagtca ccaccagaca gatcaccaga aaggcaccaa
     6721 ccgtttgcag cgccgcaacg gtcgaaaccg acagcagggt gaagaagagg atttttaatc
     6781 tgcccggatg caatccaata gcacgggcgt gattctcgtc gaaaaaggtc accataagat
     6841 ctttccattt gaaaaaaagc acgatgatcg agagaatgcc aatgatagtg agttgcagga
     6901 tatccgccgg atcgattgcc agaatattgc ccaggacgat ggtctgaatg ttcacggatg
     6961 tcgggttcaa tgacaccata aacagcccca ggccaaaaaa ggacgagaag atcaggccga
     7021 tgatggcatc ttcttttaag cgagtgagtt ggttaagaaa cagcatgctg cccgctgcca
     7081 gtccgccgga aaagaaggct cccagagaaa acggaagccc cagcatatat gcccccgcaa
     7141 cacccgggac aatagagtgc gacagcgcat cgccaatcag cgaccagcct tttagcatca
     7201 gatagcatga caggaaagcg cagagaccgc cgaccatcgc cgagacccac atcgcattga
     7261 gcatatattc atagctgaag ggttccagta gcgcgttcat ctttcttccc tctgcaccgc
     7321 tgacggtcga tgtgccacaa aagggcgttc atcgtcagta ataatgcttt cttccgagcc
     7381 gttaagtgtg acatggcgca gtacgccgct aaaagccagc tccaggttct cggctgtaaa
     7441 agtggtgtct gtcggcccgc ttgccaggac ggtgcctttg accatgaccg tataatcgca
     7501 aaatgtcgtg acggatccga gattgtgcgt tgagacaagc atcgttttgc cttccgcgcg
     7561 taactccctc aacaggctga tgattttcgc ttcggttttc acatcaacgc cggtaaaagg
     7621 ttcatccagc aggatcacat caccctgctg tgcaatcgct ctcgccagaa agacgcgttt
     7681 cttttgtcca ccggaaagct cgccgatttg tcgatggcga aaatccacca tatcgacacg
     7741 ttccagcgca tcggtgacaa tctgacgatc cctctttttg gcgatacgca acatacccat
     7801 atgcccatag cggcccatca tcaccacatc ttccaccagt acaggaaatg accagtcaac
     7861 ctcttctgac tgagggacgt aggcaaccag gtttttctgt agcgcctgtc gtgtgggaat
     7921 acccagaaca gatatcttcc cgctggtcag acgcacaaat cccataatcg ctttaaacaa
     7981 cgtcgatttt ccggaaccgt ttaccccaac cagagcggca atagatccgc ctggtactgt
     8041 gaaggatgca tcgcgcagtg ctgtgtgccc gttacgccag gtgacagtaa catcattaac
     8101 gacaatgcct gcagattgca tcattatttc tccctttttc cggctttaat tccctgtacc
     8161 agcgtactgg tagtaacctt cagaaggtcg atatacgtag gtaccgggcc gttttctgtg
     8221 ctcagggaat cgacatagag cacaccaccg tagtgcgcgc cggtttcacg cgcaacctga
     8281 cgcgctggtt tatcggaaat cgtactctcg ctaaagactg ccgggatatg atttttctta
     8341 actatatcaa caaccttacg tacctgctgc ggtgttcctt gttgatcggc attaatcggc
     8401 cacagataaa gctcttttag ccccaaatcg cgtgcgagat aagaaaaagc cccttcactg
     8461 gtgaccatcc atcgctgatt ctcagggagt tccgcaatct gcttacgcag gggggcaagg
     8521 gtttgggtaa tcttggcttt ataagtatcg gcattacgtt ggtaggtttg tgcatttgcc
     8581 ggatcgtatt ttataaacgc atcacgaata ttatcgacgt aaatcagagc attatctggc
     8641 gacatccagg catgggggtt aggtttgccc tcatagggcc cttcggtgat ccctactggc
     8701 gtcacacccg aagagacaat tacttctgga accccattga gatgctggta aaagcgttgg
     8761 aaccacaatt ccagattcat accattggcg agaatcagtt gtgccccctg cgcacgttta
     8821 atatcgccag gggtaggctg atactcatga atttctgcac caggcttggt tatggatgag
     8881 acttctgcag catctccagc cacgtttttg gccatatctg cgatgatggt aaaagttgta
     8941 atgaccttga atttttcagc tgcactcgcc tgaaatgcta tcgagcaggt gaggactagg
     9001 caccccaaga gcatggttac tttttttatt gagagcatga tttagtacct atagtgagca
     9061 aaattagaat aaacatagca actactatgt tttatagcag aagctataaa atgtaaataa
     9121 ttatcattag cgattataag atcccaacac agggattagg ttatttcctg ctgacgatgt
     9181 ggtattgagg ataaaagttg ggcagcgctt tggctttaaa atgaacttgt tcaggacgat
     9241 tggtaatggc aaagcaaaaa taatgtaggt tattggcaag ttctctagga cgcaggagag
     9301 catgaaaaac ccaggggcag tcactaaatg aagggatcgg tgatgctgcc aacttactga
     9361 tttagtgtat gatggtgttt ttgaggtgct ccagtggctt ctgtttctat cagctgtccc
     9421 tcctgttcag ctactgacgg ggtggtgcgt aacggcaaaa gcaccgccgg acatcagcgc
     9481 tatctctgct ctcactgccg taaaacatgg caactgcagt tcacttacac cgcttctcaa
     9541 cccggtacgc accagaaaat cattgatatg gccatgaatg gcgttggatg ccgggtaact
     9601 gcccgcatta tgggcgttgg cctcaacacg attttacgtc acttaaaaaa ctcaggccgc
     9661 agtcggtaac ctcgcgcata cagccgggca gtgatgtgat tgtctgcgcg gaaatggacg
     9721 aacagtgggg ctatgtcggg gctaaatcgc gccagcgctg gctgttttac gcgtatgaca
     9781 gtctccggaa gacggttgtt gcgcacgtat tcggtgaacg cactatggcg acgctggggc
     9841 gtcttatgag cctgctgtca ccctttgacg tggtgatatg gatgacggat ggctggccgc
     9901 tgtatgaatc ccgcctgaag ggaaagctgc acgtaatcag caagcgatat acgcagcgaa
     9961 ttgagcggca taacctgaat ctgaggcagc acctggcacg gctgggacgg aagtcgctgt
    10021 cgttttcaaa atcggtggag ctgcatgaca aagtcatcgg gcattatctg aacataaaac
    10081 actatcaata agttggagtc attacctgct ttttcggttg aaaagaaatt gattgaatta
    10141 ctggaaaaac aatctggtct ccatacgtct gtggattgca gtactcccct tacagagcag
    10201 agtctgtcga gaaatgacgg tgaagaccag accagaagaa acgctgaaaa tatgttcgga
    10261 gatgactgaa ctaacccagc ctggccaggg gaatatctcg ccatttagtt gtataacact
    10321 gactcaacat ttcccgtttc atttgccatt caggggcggt tcctcgcccc gcaaaccaca
    10381 ctttcccttt tcccgactgg ttcagttcat cgagtgtttt cattaacttt tcactgtttt
    10441 tacggggctg gatttcatca aataatcccg gctgcgctat acccgatggt gtgaaatcag
    10501 ccagcatgac tcctgccttc atatagcggt acccttcacg ccagacatgg tttaaggctc
    10561 tgcatgcggc ggcaataatg tcccggctgt cctgtgtggg taatgaaagc ttttccacag
    10621 cggcattgct gtaacagggt tcagggggat gtccgtacaa atgtcgtcac ctgccggcaa
    10681 tactgacgct ccccacgtag tttctctgcg gcccgctctg catactgaac aacagcctgg
    10741 tgcatggcat ctttgtctgt gattcgttca ccaaaactgc gactatgtca acgccacgat
    10801 gtttgaccgt tatttgccat tttcatgccc gctaaatact ttcgttactg atgctgtccg
    10861 ctttgcacca tttcatcatc actgattggc gttgtgtttt tggtcagcac tccagcttta
    10921 cgtttctctt ttaaccggta actctctcct tgttcttttt gacggacgca ttttacgttt
    10981 gggctggatg tagtaacgca gcatggaacg tccgcccgta taacccattg ccttaatctc
    11041 cgcgaagata acctcgctat tccagacatt ctctgccagg cgcatgtcga tgtaatccat
    11101 aaacggtttc agcttaacca ttttgtggcg ggtctttctg gctggcggtt cagggtattt
    11161 gaggtagcgt ctgaccgtcc gttcagagca accaatctga gccgcaatat cgacaatgta
    11221 cgcgccctgc tggcgcattt gctttatcat gtaaaagtcc tctctgctca gcatgttgat
    11281 gtcctttctg gtgtgagaac cttaaggaaa caacatgttg ggtggagcgg acaatccaaa
    11341 tggtgaatta ccgtcttata tcactggcgc tgacacctgt agtttgtata cacaatccct
    11401 ggcattgaaa cacacatatg aagtgtactt cggatatgac cgtacgctca ggaagtacgg
    11461 cagattccgt caaaaattac ctgtaaagac agacatcaga aaaaacagtg ctcgccgcag
    11521 accggtgacc gggcgaagcc cgcgaaccgg cgaggaagcg caatgtatct gtagttacag
    11581 ggagcaggta cgccctgaag ccctttcata aaacggttgt gtgcgctgtc cttctggaat
    11641 gatttatcca catatccgga ggcccgatcc agtaaacaga tccatgaatg atcaacaaag
    11701 gatccattaa agatccccat atcgctgcaa accttgtcac tcatgggccg ggaccacgat
    11761 cacataagct gtggcatgtt actgataaac tgtaacatgc taatgataag ctgtattcag
    11821 taatccatat actgaagtaa gttaatgaca taaactatgg tcagtatgcc agactcagtt
    11881 gttaaataca ggctgcaggt ttttcttcag tcagttagcg gagttctgac acacgatttt
    11941 ctgtttattc ttttactgtc cacaggctgg aggctttctg gaaaacgaaa attcagacat
    12001 caaaaaactg ttcggcgagg tggataagtc ctccggtgag ctggtgacac tgacaccaaa
    12061 caataacaac accgtacaac ctgtggcgct gatgcgtctg ggcgtttttg taccgaccct
    12121 taaatcactg aagaacagta aaaaaaatac actgtcacgt actgatgcca cggaagagct
    12181 gacacgtctt tccctggccc gtgctgaggg attcgataag gttgagatca ccggcccccg
    12241 cctggatatg gataatgatt tcaagacctg ggtggggatc attcattcct ttgcccgcca
    12301 taacgtgatt ggtgacaaag ttgaactgcc ttttgttgag tttgcaaaac tgtgtggtat
    12361 accttcaagc cagtcatccc gcaggctgcg tgagcgcatc agcccttccc tgaagcgcat
    12421 tgccggtacc gtgatttcgt tttcccgtac cgatgagaag cacacccggg aatatatcac
    12481 ccatctggta cagtcagctt actacgatac tgagcgggat attgtgcagt tacaggccga
    12541 tccccgcctg tttgaactgt accagtttga cagaaaagtc cttctccagc ttaaggcgat
    12601 taatgccctg aagcgacggg agtccgccca ggcactctac acctttatag agagcctgcc
    12661 ccgggatccg gcaccgatat cgctggcgcg gctgcgtgca cgcctcaatc tgaagtctcc
    12721 tgtattttcc cagaaccaga cggtcagacg ggcaatggag cagttgcgcg agattggata
    12781 tcttgattac acggagatcc agcgggggcg gacaaaattc ttctgtattc actaccggcg
    12841 tccccggtta aaagcgccga atgacgagag taaggaaaat ccgttgcaac cttcacctgc
    12901 ggaaaaagtc agtccggaga tggcggagaa gcttgccctg cttgagaaac tgggcatcac
    12961 gctggatgac ctggaaaaac tcttcaaatc ccgctgaaca taaactgtag tcagtgaaga
    13021 gcgctccttt actgactaca gcttatatta accggtgcag tgagtggtct gctcactgca
    13081 gtttatattc tgtttcctgc agtgctgtct gtagctgagc tgccatctgc ctgtccctta
    13141 cgtaagtgat cccgtaacct gatgctgagg cattgctccc ttcataaaac atgacttact
    13201 cactacagct tatatacatg ctccagctta tgttatgtct gttctgctga ccacagctta
    13261 tataaggaag cgcgtatgcc gtcacctcag gggaggcagt gtacgcagga tctccgcagc
    13321 atcccgcccg tcacctgtga aaggcactgc cagcgtggca gccatatcca gtgcaaacac
    13381 tctggtataa acctccatcg aacgtggatc cctgtgacca gccagtgcct ggatgacttt
    13441 ccggggctgg cggtgataga gcatgtgcat gatatagctg tgccggaagg tgtgtggtgt
    13501 gaccggaatc gaaaagtgta ctccgtcagc ttcggcccgt ctgacagcct gcttcagcca
    13561 gttgcgcatg gtttcgtcgg tcacggccca taatggttca cgacgacggg gccgggtggt
    13621 gatcatccag ctttccatct gcctgacata gcttatatct gtcagcggaa ccaggcgcac
    13681 ttcatctttt ggcgggcgtc cgcgtcgcgc acgcactttt tcggacagga tccgcacaaa
    13741 cggtcttact ccattcaggt caaatgattc cggcgtcagc atccgggctt cgccaatacg
    13801 cattccggta ttccagaggg tggcgaacag catatggtga cgctgatccg gcatatagaa
    13861 aagaagggca ctcacttccg gggccagcag gtaggccggt gtggcccccg tggaagtggc
    13921 cattcttctc agggagagcg ctgttgcaaa atccaccccc ggcgcaatgg gtaacaggga
    13981 gacgcgttct ggtgaattct gcaggggaat gacattgttc atgagttatt tttcacgtag
    14041 cacacgcact gtttatggat acaggtattc tgacctgaac gcccggatcc ttccacgaca
    14101 ataaatcgca gcgcgcggat ccttttgttt gattatcacg cattattgcg ggtaaaacca
    14161 aatacgtaaa ggcgcatttt gccgctggga tcccgtctta agccagtcat ggtgcgggct
    14221 gagggctggt ttactgtttt tgggagaatt ggggtaatgc caggacaggc agaaacggag
    14281 aaaaaatcct gcagacgccc ttaaaagaca actgaaaatt tctgactcca tattcctctg
    14341 gtttcagact gcttaatcac atcatcaacc tgatacataa caaacagatt ctgttcacag
    14401 aatgaacaat taagtaaatg gttagattat gcgaaaaagt acagatattt ctcaccatcg
    14461 ttattgaata atatgtcttc acacaaacaa tattaatatt ttgagtgtaa gccctgactc
    14521 aaagaaagaa atgtctgttt tcggaatcaa aaatatatag ttatcaaaat acattaattt
    14581 caaatttgaa attaatgtaa aacgatttag taaatgttat gatattataa atctactcct
    14641 ccatgtttag aggagtattt gcagactgga cgctcttata tagttactta cctttataca
    14701 tattctaaca taagcattta ccaaccttac agggaacaga ccatagtagt ttatatttcc
    14761 attcaggtct gaatgcaccg atagaatata tcatcttttt attattatcc tgacaatacc
    14821 ttcgcgcttt atctatattc agccacataa ggacacttcc cggacttagt ttcatgcaat
    14881 tctcatcatt cagaactgca ccatttggaa cgtcataata aacattacat gagctttcag
    14941 atttcagtac tatatcaata gcacacggtt tattatccca gaatagcaca tggccaaaca
    15001 taagttctcg taagtgagaa ataaacatta acagattatc atattcgtag caaggtaggg
    15061 tacctccaaa ccgggaatga aaaagtgata tataagagct ggatatttct ttatcggata
    15121 acttgcttat acacttaatc tctccgccat tcctgataaa tcgctggatt tcatttcggc
    15181 gagttttttc aaatttaggt gaaaaagatt cctttataat acaattttgt ttttttctgg
    15241 ctattttcca tgttgcattg ataatatttt gtttatttat aattgataat ttattagttt
    15301 tatccggaaa aaaacatctt gcatgtgggg aaaaaggaat taatacctca tcagatgaaa
    15361 gaggataaga ccttcttgcc attatcccaa tttgttttcc attgcacaga aaatatgagc
    15421 ctttgatatc accatctttt tcatagtgaa aaaaatcaaa cttccagtca tgatgtatca
    15481 taaagtatga aacaacatcc ggatgcatgt ttacactacc accgtatttt tcaaaagttt
    15541 ttttgtacgt ttcgaatgta gatggtttcc aggccgtaat aatgcgcttt atatttttaa
    15601 ttgacaaagt catatcctcg gcgtttttat atattatgag tgcaacacca acaataattc
    15661 tgattatgat aaatattatt taaaatcaac ttccatttgt tgttgaattg aaaggtgttt
    15721 tgtcgtttct atacagtatt taatataatc agtaaacttt ggcggtttag gcattccgat
    15781 actcagtagc ttgtcgttac tgaaacaaac attgagcata ctgaacgctc catataaacg
    15841 aatggctttt aacataaggc gttcgttaca gggaccaaaa atatttttaa aatcatgacg
    15901 gctcattgcc agtatgtcat aactgacttt agtatatctg tctccaacag gatcacagtt
    15961 caaagcacgg gctacagctt cgtcaatagc agagaacgtc acactacttt ctttacctgc
    16021 tgatatatga acaatctcac cattaattaa cgagctttca agcaacatta gcaatgcatc
    16081 agcacaataa tctacaggga taacatctat tttatcatcc agagagcaca taaatttttg
    16141 caacattaac cccattctga atacccagaa aatactggtt gaaggtaagc accctaaacg
    16201 actgtggcca acaataattg atggtcgggc aaccaacaaa ggtaaatcag gacactg
//
